GPR149

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of action potential (GO:0045760)9.21440835
2positive regulation of synaptic transmission, GABAergic (GO:0032230)9.03381980
3regulation of glucocorticoid secretion (GO:2000849)8.14203185
4negative regulation of heart rate (GO:0010459)7.24023957
5positive regulation of digestive system process (GO:0060456)7.19951124
6regulation of corticosteroid hormone secretion (GO:2000846)7.05268601
7pyrimidine nucleobase catabolic process (GO:0006208)7.02244409
8positive regulation of steroid hormone secretion (GO:2000833)6.37212926
9short-term memory (GO:0007614)5.63416416
10positive regulation of renal sodium excretion (GO:0035815)5.57152872
11nucleobase catabolic process (GO:0046113)5.52453793
12dendritic spine morphogenesis (GO:0060997)5.46908481
13regulation of action potential (GO:0098900)5.39237303
14regulation of steroid hormone secretion (GO:2000831)5.36278646
15negative regulation of axon guidance (GO:1902668)5.29904724
16neurotransmitter-gated ion channel clustering (GO:0072578)5.28446987
17negative regulation of Ras GTPase activity (GO:0034261)5.08664453
18regulation of synaptic transmission, GABAergic (GO:0032228)4.98745417
19neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)4.97558052
20negative regulation of calcium ion transport into cytosol (GO:0010523)4.95544801
21protein localization to synapse (GO:0035418)4.64411084
22retinal ganglion cell axon guidance (GO:0031290)4.62864595
23detection of temperature stimulus involved in sensory perception of pain (GO:0050965)4.56452245
24detection of temperature stimulus involved in sensory perception (GO:0050961)4.56452245
25positive regulation of growth hormone secretion (GO:0060124)4.45294634
26G-protein coupled receptor internalization (GO:0002031)4.44495220
27neurofilament cytoskeleton organization (GO:0060052)4.44292868
28long-term memory (GO:0007616)4.42436951
29negative regulation of amino acid transport (GO:0051956)4.40528868
30ribonucleoprotein complex disassembly (GO:0032988)4.35523172
31establishment of mitochondrion localization (GO:0051654)4.30855885
32regulation of collateral sprouting (GO:0048670)4.28874327
33regulation of feeding behavior (GO:0060259)4.26712459
34behavioral response to nicotine (GO:0035095)4.16025768
35regulation of protein kinase A signaling (GO:0010738)4.14514891
36central nervous system projection neuron axonogenesis (GO:0021952)4.13820765
37histamine secretion (GO:0001821)4.13802606
38cellular response to ATP (GO:0071318)4.13227071
39behavioral fear response (GO:0001662)4.12626354
40behavioral defense response (GO:0002209)4.12626354
41regulation of integrin activation (GO:0033623)4.09998415
42positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.09320400
43regulation of growth hormone secretion (GO:0060123)4.06354825
44axonal fasciculation (GO:0007413)4.00070617
45peristalsis (GO:0030432)3.99362628
46establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.98753108
47mitochondrion transport along microtubule (GO:0047497)3.98753108
48positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.98446178
49response to morphine (GO:0043278)3.96002033
50response to pain (GO:0048265)3.94467484
51detection of temperature stimulus (GO:0016048)3.91795799
52positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.91610126
53positive regulation of dendritic spine morphogenesis (GO:0061003)3.87046698
54regulation of short-term neuronal synaptic plasticity (GO:0048172)3.78916354
55negative regulation of neurotransmitter secretion (GO:0046929)3.77627241
56regulation of acute inflammatory response to antigenic stimulus (GO:0002864)3.76955180
57response to isoquinoline alkaloid (GO:0014072)3.74823065
58organelle disassembly (GO:1903008)3.71921823
59hindbrain development (GO:0030902)3.71742150
60negative regulation of axon extension involved in axon guidance (GO:0048843)3.69855562
61multicellular organismal response to stress (GO:0033555)3.66744534
62behavioral response to ethanol (GO:0048149)3.66315430
63dendritic spine organization (GO:0097061)3.65925847
64establishment of nucleus localization (GO:0040023)3.65281729
65regulation of glutamate secretion (GO:0014048)3.62098329
66transmission of nerve impulse (GO:0019226)3.61945048
67regulation of renal sodium excretion (GO:0035813)3.57600601
68sensory perception of pain (GO:0019233)3.54224599
69epithelial cell differentiation involved in kidney development (GO:0035850)3.50852066
70central nervous system neuron axonogenesis (GO:0021955)3.50722114
71organelle transport along microtubule (GO:0072384)3.49998091
72positive regulation of heat generation (GO:0031652)3.48042388
73positive regulation of gastrulation (GO:2000543)3.47808131
74negative regulation of glial cell proliferation (GO:0060253)3.46833738
75negative regulation of amine transport (GO:0051953)3.44877506
76fear response (GO:0042596)3.42900773
77positive regulation of neurological system process (GO:0031646)3.42715192
78negative regulation of heart contraction (GO:0045822)3.42405356
79synapse assembly (GO:0007416)3.41962753
80regulation of axon guidance (GO:1902667)3.39350652
81neuron recognition (GO:0008038)3.38949721
82mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)3.37110037
83positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021103.37110037
84aggressive behavior (GO:0002118)3.32553759
85synaptic vesicle endocytosis (GO:0048488)3.30029420
86regulation of synapse structural plasticity (GO:0051823)3.28581388
87positive regulation of amino acid transport (GO:0051957)3.25527510
88regulation of fever generation (GO:0031620)3.24833881
89protein targeting to Golgi (GO:0000042)3.23508002
90activation of adenylate cyclase activity (GO:0007190)3.21313400
91nonmotile primary cilium assembly (GO:0035058)3.21238804
92regulation of cell maturation (GO:1903429)3.20243361
93establishment of protein localization to Golgi (GO:0072600)3.19090239
94calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.18900367
95regulation of synaptic transmission, glutamatergic (GO:0051966)3.18545250
96neuronal ion channel clustering (GO:0045161)3.18426135
97layer formation in cerebral cortex (GO:0021819)3.17781643
98vesicle transport along microtubule (GO:0047496)3.17547213
99negative regulation of hormone metabolic process (GO:0032351)3.16485722
100negative regulation of hormone biosynthetic process (GO:0032353)3.16485722
101presynaptic membrane assembly (GO:0097105)3.14129722
102positive regulation of synapse maturation (GO:0090129)3.13609480
103synaptic vesicle docking involved in exocytosis (GO:0016081)3.12104672
104positive regulation of membrane potential (GO:0045838)3.11516415
105spinal cord development (GO:0021510)3.09331240
106myelin assembly (GO:0032288)3.08213108
107histamine transport (GO:0051608)3.07446474
108regulation of voltage-gated calcium channel activity (GO:1901385)3.05018035
109cell migration in hindbrain (GO:0021535)3.03646584
110regulation of female gonad development (GO:2000194)3.03261510
111negative regulation of catecholamine secretion (GO:0033604)3.02306356
112postsynaptic membrane organization (GO:0001941)3.02014399
113negative regulation of microtubule polymerization (GO:0031115)3.00906709
114ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.97778779
115regulation of excretion (GO:0044062)2.97607877
116positive regulation of adenylate cyclase activity (GO:0045762)2.96734533
117negative regulation of homotypic cell-cell adhesion (GO:0034111)2.96653973
118cranial nerve morphogenesis (GO:0021602)2.96190329
119axoneme assembly (GO:0035082)2.95796198
120retinal cone cell development (GO:0046549)2.94177843
121establishment of melanosome localization (GO:0032401)2.92025771
122positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.91389327
123dendrite development (GO:0016358)2.91347330
124regulation of heat generation (GO:0031650)2.90848640
125neuron projection extension involved in neuron projection guidance (GO:1902284)2.90443963
126axon extension involved in axon guidance (GO:0048846)2.90443963
127negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.90047133
128regulation of mitochondrial fission (GO:0090140)2.89531468
129protein polyglutamylation (GO:0018095)2.89363150
130melanosome transport (GO:0032402)2.88798627
131retrograde transport, vesicle recycling within Golgi (GO:0000301)2.88705947
132membrane hyperpolarization (GO:0060081)2.87870754
133vesicle localization (GO:0051648)2.87826491
134axon extension (GO:0048675)2.87233714
135auditory behavior (GO:0031223)2.86580681
136positive regulation of mitochondrial fission (GO:0090141)2.85916743
137piRNA metabolic process (GO:0034587)2.85380009
138response to pheromone (GO:0019236)2.85350604
139presynaptic membrane organization (GO:0097090)2.84872267
140negative regulation of axonogenesis (GO:0050771)2.84178546
141establishment of pigment granule localization (GO:0051905)2.83356872
142neuronal action potential (GO:0019228)2.83334334
143neuropeptide signaling pathway (GO:0007218)2.82570898
144proline transport (GO:0015824)2.80326441
145pigment granule transport (GO:0051904)2.79882375
146glycosphingolipid biosynthetic process (GO:0006688)2.78308090
147synaptic vesicle maturation (GO:0016188)2.77268055
148neuronal action potential propagation (GO:0019227)2.77076639
149regulation of meiosis (GO:0040020)2.76694314
150negative regulation of blood circulation (GO:1903523)2.76673930
151phasic smooth muscle contraction (GO:0014821)2.75961828
152positive regulation of Rap GTPase activity (GO:0032854)2.75415320
153glutamate secretion (GO:0014047)2.74558192
154positive regulation of synaptic transmission (GO:0050806)2.73643583
155negative regulation of potassium ion transport (GO:0043267)2.71351407
156positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-2.68018333
157regulation of dopamine secretion (GO:0014059)2.67134500
158microtubule polymerization or depolymerization (GO:0031109)2.66716809
159positive regulation of actin filament depolymerization (GO:0030836)2.66386429
160cAMP-mediated signaling (GO:0019933)2.65325668
161negative regulation of smooth muscle contraction (GO:0045986)2.65131882
162negative regulation of smooth muscle cell differentiation (GO:0051151)2.63049442
163positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.62720611
164regulation of endocrine process (GO:0044060)2.62028413
165regulation of Rap GTPase activity (GO:0032317)2.59499071
166innervation (GO:0060384)2.56678809
167neuron projection extension (GO:1990138)2.55696071
168chemosensory behavior (GO:0007635)2.47624427
169activation of protein kinase A activity (GO:0034199)2.47431370
170negative regulation of acute inflammatory response (GO:0002674)2.46696872
171regulation of synaptic vesicle exocytosis (GO:2000300)2.46457157
172sequestering of actin monomers (GO:0042989)2.45362456
173positive regulation of acute inflammatory response (GO:0002675)2.45173018
174regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.42946974
175positive regulation of vasodilation (GO:0045909)2.42321852
176chondrocyte proliferation (GO:0035988)2.41465010
177positive regulation of cyclase activity (GO:0031281)2.41000534
178negative regulation of GTPase activity (GO:0034260)2.40932606
179negative regulation of GTP catabolic process (GO:0033125)2.40932606
180ovulation cycle (GO:0042698)2.40041757
181regulation of synaptic vesicle transport (GO:1902803)2.39190531
182regulation of neuronal synaptic plasticity (GO:0048168)2.39087457
183learning (GO:0007612)2.38783581
184tachykinin receptor signaling pathway (GO:0007217)11.5928180

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse4.97460601
2EZH2_22144423_ChIP-Seq_EOC_Human4.11142813
3GBX2_23144817_ChIP-Seq_PC3_Human3.76115565
4SMAD_19615063_ChIP-ChIP_OVARY_Human3.38140034
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.66602334
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.43952734
7SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.37978558
8* BMI1_23680149_ChIP-Seq_NPCS_Mouse2.27613795
9JARID2_20064375_ChIP-Seq_MESCs_Mouse2.23256553
10GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.22158681
11* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.12695225
12NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.10337108
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.10167089
14IRF1_19129219_ChIP-ChIP_H3396_Human2.09779092
15RNF2_18974828_ChIP-Seq_MESCs_Mouse2.05741676
16EZH2_18974828_ChIP-Seq_MESCs_Mouse2.05741676
17* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.01326770
18TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.01087113
19TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.00629473
20* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.00455288
21AR_21572438_ChIP-Seq_LNCaP_Human1.99724062
22* EED_16625203_ChIP-ChIP_MESCs_Mouse1.98603183
23* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.98482864
24* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.97648572
25NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.96830116
26JARID2_20075857_ChIP-Seq_MESCs_Mouse1.94069632
27P300_19829295_ChIP-Seq_ESCs_Human1.90774070
28SMAD4_21799915_ChIP-Seq_A2780_Human1.88324221
29* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.86590711
30EZH2_27304074_Chip-Seq_ESCs_Mouse1.81669208
31IGF1R_20145208_ChIP-Seq_DFB_Human1.80276909
32SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.78496428
33CDX2_19796622_ChIP-Seq_MESCs_Mouse1.77101152
34ESR1_20079471_ChIP-ChIP_T-47D_Human1.71185371
35TOP2B_26459242_ChIP-Seq_MCF-7_Human1.70569610
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.67847125
37MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.67356072
38NR3C1_23031785_ChIP-Seq_PC12_Mouse1.62422789
39POU3F2_20337985_ChIP-ChIP_501MEL_Human1.61889261
40TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.56555955
41POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.56555955
42* REST_21632747_ChIP-Seq_MESCs_Mouse1.56457046
43EZH2_27294783_Chip-Seq_ESCs_Mouse1.55983100
44RNF2_27304074_Chip-Seq_ESCs_Mouse1.54912405
45CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.54652178
46EP300_21415370_ChIP-Seq_HL-1_Mouse1.51455826
47RNF2_27304074_Chip-Seq_NSC_Mouse1.51310726
48* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.50443823
49CTBP1_25329375_ChIP-Seq_LNCAP_Human1.48996645
50STAT3_23295773_ChIP-Seq_U87_Human1.44984225
51STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.44669222
52AR_25329375_ChIP-Seq_VCAP_Human1.42438441
53FUS_26573619_Chip-Seq_HEK293_Human1.41913462
54TAF15_26573619_Chip-Seq_HEK293_Human1.41499663
55CBX2_27304074_Chip-Seq_ESCs_Mouse1.40344901
56SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40282652
57CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.39684933
58IKZF1_21737484_ChIP-ChIP_HCT116_Human1.39519373
59ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.39047505
60SUZ12_27294783_Chip-Seq_ESCs_Mouse1.36718891
61MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.35374616
62DROSHA_22980978_ChIP-Seq_HELA_Human1.35240470
63RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.27833094
64* PIAS1_25552417_ChIP-Seq_VCAP_Human1.27038151
65TP53_16413492_ChIP-PET_HCT116_Human1.26723588
66PRDM14_20953172_ChIP-Seq_ESCs_Human1.25938452
67YAP1_20516196_ChIP-Seq_MESCs_Mouse1.25367634
68* SOX2_21211035_ChIP-Seq_LN229_Gbm1.24756612
69NANOG_18555785_Chip-Seq_ESCs_Mouse1.23585188
70TP53_18474530_ChIP-ChIP_U2OS_Human1.23058813
71ZNF274_21170338_ChIP-Seq_K562_Hela1.21985180
72UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.20950938
73FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.20318409
74* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.18613292
75JUN_21703547_ChIP-Seq_K562_Human1.17661762
76* P53_22127205_ChIP-Seq_FIBROBLAST_Human1.16841301
77* REST_18959480_ChIP-ChIP_MESCs_Mouse1.16686110
78MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.15784276
79* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.15025634
80RUNX2_22187159_ChIP-Seq_PCA_Human1.14728642
81KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.14311499
82FLI1_27457419_Chip-Seq_LIVER_Mouse1.14138097
83* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.13383924
84ETV2_25802403_ChIP-Seq_MESCs_Mouse1.12464539
85RARB_27405468_Chip-Seq_BRAIN_Mouse1.12048988
86PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.11839549
87TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.10971426
88SMAD3_21741376_ChIP-Seq_EPCs_Human1.09319966
89GATA1_26923725_Chip-Seq_HPCs_Mouse1.09111524
90* KDM2B_26808549_Chip-Seq_REH_Human1.08916883
91TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08628604
92RBPJ_22232070_ChIP-Seq_NCS_Mouse1.08577566
93KLF5_20875108_ChIP-Seq_MESCs_Mouse1.07472128
94RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.07447759
95NR3C1_21868756_ChIP-Seq_MCF10A_Human1.07412944
96RXR_22108803_ChIP-Seq_LS180_Human1.06153787
97LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06114693
98NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.05664501
99NRF2_20460467_ChIP-Seq_MEFs_Mouse1.05664501
100ZNF217_24962896_ChIP-Seq_MCF-7_Human1.05274360
101SALL1_21062744_ChIP-ChIP_HESCs_Human1.04529915
102OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.03970312
103CJUN_26792858_Chip-Seq_BT549_Human1.03245410
104RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.03097485
105* E2F1_18555785_Chip-Seq_ESCs_Mouse1.02391268
106TAL1_26923725_Chip-Seq_HPCs_Mouse1.01739660
107PCGF2_27294783_Chip-Seq_ESCs_Mouse1.00921316
108* ER_23166858_ChIP-Seq_MCF-7_Human1.00835453
109SMAD3_21741376_ChIP-Seq_ESCs_Human1.00785155
110EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.00690199
111PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.00232199
112AR_19668381_ChIP-Seq_PC3_Human0.99968296
113* TCF4_23295773_ChIP-Seq_U87_Human0.99755342
114VDR_22108803_ChIP-Seq_LS180_Human0.99223341
115ERG_21242973_ChIP-ChIP_JURKAT_Human0.99110799
116TP53_22573176_ChIP-Seq_HFKS_Human0.98468847
117EWS_26573619_Chip-Seq_HEK293_Human0.96601368
118CMYC_18555785_Chip-Seq_ESCs_Mouse0.95255110
119WT1_25993318_ChIP-Seq_PODOCYTE_Human0.94957005
120CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94669266
121* REST_19997604_ChIP-ChIP_NEURONS_Mouse0.94526102
122WDR5_24793694_ChIP-Seq_LNCAP_Human0.92023293
123SOX2_18555785_ChIP-Seq_MESCs_Mouse0.91562086
124EGR1_19032775_ChIP-ChIP_M12_Human0.89183894
125STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.88998937
126IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.87046062
127CBP_20019798_ChIP-Seq_JUKART_Human0.87046062

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010386_abnormal_urinary_bladder6.81205430
2MP0002735_abnormal_chemical_nociception5.61045224
3MP0001968_abnormal_touch/_nociception3.76910138
4MP0006276_abnormal_autonomic_nervous3.45870366
5MP0004270_analgesia3.24175947
6MP0002736_abnormal_nociception_after3.23633900
7MP0004859_abnormal_synaptic_plasticity3.10847467
8MP0001986_abnormal_taste_sensitivity2.98182243
9MP0005499_abnormal_olfactory_system2.77557954
10MP0005394_taste/olfaction_phenotype2.77557954
11MP0001970_abnormal_pain_threshold2.72900751
12MP0002734_abnormal_mechanical_nocicepti2.60131078
13MP0003011_delayed_dark_adaptation2.54381028
14MP0002638_abnormal_pupillary_reflex2.51304829
15MP0004858_abnormal_nervous_system2.33869598
16MP0004145_abnormal_muscle_electrophysio2.33112051
17MP0001188_hyperpigmentation2.30549474
18MP0002572_abnormal_emotion/affect_behav2.25255007
19MP0002733_abnormal_thermal_nociception2.23189818
20MP0003880_abnormal_central_pattern2.15223789
21MP0002160_abnormal_reproductive_system2.13324842
22MP0002063_abnormal_learning/memory/cond2.07889392
23MP0003635_abnormal_synaptic_transmissio2.07293065
24MP0003890_abnormal_embryonic-extraembry2.06598888
25MP0008789_abnormal_olfactory_epithelium2.06588111
26MP0009745_abnormal_behavioral_response2.02511221
27MP0001440_abnormal_grooming_behavior1.99518409
28MP0002653_abnormal_ependyma_morphology1.95843807
29MP0003941_abnormal_skin_development1.95028414
30MP0005451_abnormal_body_composition1.87268556
31MP0003646_muscle_fatigue1.77213061
32MP0003718_maternal_effect1.76780295
33MP0005551_abnormal_eye_electrophysiolog1.74894078
34MP0002184_abnormal_innervation1.74574085
35MP0002102_abnormal_ear_morphology1.65982620
36MP0005253_abnormal_eye_physiology1.57962132
37MP0001905_abnormal_dopamine_level1.56399558
38MP0001984_abnormal_olfaction1.52775968
39MP0005386_behavior/neurological_phenoty1.47243952
40MP0004924_abnormal_behavior1.47243952
41MP0002272_abnormal_nervous_system1.45580860
42MP0001529_abnormal_vocalization1.44978646
43MP0005623_abnormal_meninges_morphology1.40896171
44MP0008775_abnormal_heart_ventricle1.37384365
45MP0009046_muscle_twitch1.36910498
46MP0001485_abnormal_pinna_reflex1.36462470
47MP0004133_heterotaxia1.35769965
48MP0002928_abnormal_bile_duct1.34358519
49MP0004484_altered_response_of1.32969940
50MP0002254_reproductive_system_inflammat1.31447616
51MP0009250_abnormal_appendicular_skeleto1.31256962
52MP0002064_seizures1.31190540
53MP0005423_abnormal_somatic_nervous1.29100433
54MP0000749_muscle_degeneration1.27890320
55MP0002067_abnormal_sensory_capabilities1.27654828
56MP0004142_abnormal_muscle_tone1.27033606
57MP0001299_abnormal_eye_distance/1.22180940
58MP0002229_neurodegeneration1.21869073
59MP0003329_amyloid_beta_deposits1.20789406
60MP0002152_abnormal_brain_morphology1.20245716
61MP0000751_myopathy1.19593978
62MP0005195_abnormal_posterior_eye1.19247106
63MP0001486_abnormal_startle_reflex1.18413131
64MP0003091_abnormal_cell_migration1.17859178
65MP0002822_catalepsy1.17662005
66MP0003122_maternal_imprinting1.13709107
67MP0003121_genomic_imprinting1.10049779
68MP0003315_abnormal_perineum_morphology1.09976743
69MP0001919_abnormal_reproductive_system1.07437758
70MP0001727_abnormal_embryo_implantation1.07076128
71MP0005389_reproductive_system_phenotype1.06902670
72MP0003221_abnormal_cardiomyocyte_apopto1.06761584
73MP0005187_abnormal_penis_morphology1.06650566
74MP0000534_abnormal_ureter_morphology1.06560013
75MP0005646_abnormal_pituitary_gland1.05333927
76MP0005645_abnormal_hypothalamus_physiol1.05099287
77MP0001542_abnormal_bone_strength1.04160582
78MP0005171_absent_coat_pigmentation1.03814116
79MP0000569_abnormal_digit_pigmentation1.03272076
80MP0002557_abnormal_social/conspecific_i1.03213562
81MP0005391_vision/eye_phenotype0.99859984
82MP0000427_abnormal_hair_cycle0.99843509
83MP0000631_abnormal_neuroendocrine_gland0.99660562
84MP0008004_abnormal_stomach_pH0.98800893
85MP0001502_abnormal_circadian_rhythm0.97714824
86MP0002972_abnormal_cardiac_muscle0.95961628
87MP0004036_abnormal_muscle_relaxation0.95956854
88MP0003861_abnormal_nervous_system0.93799027
89MP0004085_abnormal_heartbeat0.93395296
90MP0002882_abnormal_neuron_morphology0.92697930
91MP0000604_amyloidosis0.91904969
92MP0003123_paternal_imprinting0.91848582
93MP0008569_lethality_at_weaning0.90423447
94MP0000579_abnormal_nail_morphology0.89762876
95MP0002751_abnormal_autonomic_nervous0.86721029
96MP0001324_abnormal_eye_pigmentation0.85857228
97MP0005395_other_phenotype0.85248006
98MP0000537_abnormal_urethra_morphology0.84668676
99MP0002332_abnormal_exercise_endurance0.84418313
100MP0004510_myositis0.82310461
101MP0004742_abnormal_vestibular_system0.82116698
102MP0000778_abnormal_nervous_system0.81755478
103MP0002752_abnormal_somatic_nervous0.81525081
104MP0002066_abnormal_motor_capabilities/c0.81399604
105MP0004084_abnormal_cardiac_muscle0.81020013
106MP0008877_abnormal_DNA_methylation0.80926242
107MP0006292_abnormal_olfactory_placode0.79481452
108MP0001756_abnormal_urination0.79147794
109MP0004811_abnormal_neuron_physiology0.78456944
110MP0008961_abnormal_basal_metabolism0.78010257
111MP0000639_abnormal_adrenal_gland0.75801310
112MP0001293_anophthalmia0.75703978
113MP0002090_abnormal_vision0.75693787
114MP0005257_abnormal_intraocular_pressure0.74587786
115MP0003787_abnormal_imprinting0.73566274
116MP0005620_abnormal_muscle_contractility0.73288001
117MP0000372_irregular_coat_pigmentation0.72284515
118MP0001501_abnormal_sleep_pattern0.71791987
119MP0003879_abnormal_hair_cell0.71573537
120MP0003942_abnormal_urinary_system0.70887136
121MP0005084_abnormal_gallbladder_morpholo0.70716060
122MP0003632_abnormal_nervous_system0.70134410
123MP0009697_abnormal_copulation0.69510595
124MP0003633_abnormal_nervous_system0.68560553
125MP0001177_atelectasis0.68377684
126MP0002069_abnormal_eating/drinking_beha0.67721434
127MP0004043_abnormal_pH_regulation0.67422669
128MP0002909_abnormal_adrenal_gland0.67288592
129MP0004883_abnormal_blood_vessel0.66502266
130MP0002233_abnormal_nose_morphology0.66332239
131MP0004233_abnormal_muscle_weight0.66230646
132MP0000955_abnormal_spinal_cord0.65878534
133MP0003631_nervous_system_phenotype0.65464216
134MP0004134_abnormal_chest_morphology0.65248439
135MP0008872_abnormal_physiological_respon0.64538803
136MP0000759_abnormal_skeletal_muscle0.63989653
137MP0009384_cardiac_valve_regurgitation0.63688398
138MP0000538_abnormal_urinary_bladder0.62654319
139MP0010030_abnormal_orbit_morphology0.62255896
140MP0008874_decreased_physiological_sensi0.62199684
141MP0003385_abnormal_body_wall0.61258289
142MP0003755_abnormal_palate_morphology0.60942872
143MP0003698_abnormal_male_reproductive0.60878257
144* MP0003699_abnormal_female_reproductive0.60807042
145MP0006072_abnormal_retinal_apoptosis0.60078545
146MP0002269_muscular_atrophy0.60038340
147MP0001963_abnormal_hearing_physiology0.57868511
148MP0002177_abnormal_outer_ear0.57730686
149MP0002249_abnormal_larynx_morphology0.57418866
150MP0005197_abnormal_uvea_morphology0.57348775
151MP0006138_congestive_heart_failure0.56795816

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)6.01525435
2Cortical dysplasia (HP:0002539)4.58596845
3Polyphagia (HP:0002591)4.31446580
4Amyotrophic lateral sclerosis (HP:0007354)4.25762984
5Aplasia/Hypoplasia of the brainstem (HP:0007362)3.92189788
6Hypoplasia of the brainstem (HP:0002365)3.92189788
7Drooling (HP:0002307)3.79200272
8Abnormal gallbladder physiology (HP:0012438)3.62070869
9Cholecystitis (HP:0001082)3.62070869
10Abnormality of the corticospinal tract (HP:0002492)3.58315469
11Excessive salivation (HP:0003781)3.52619646
12Medial flaring of the eyebrow (HP:0010747)3.44302102
13Obstructive sleep apnea (HP:0002870)3.37634497
14Megalencephaly (HP:0001355)3.34041947
15Limb dystonia (HP:0002451)3.30710129
16Genetic anticipation (HP:0003743)3.28225819
17Amblyopia (HP:0000646)3.28187170
18Short nail (HP:0001799)3.26839492
19Specific learning disability (HP:0001328)3.24545099
20Exotropia (HP:0000577)3.20610032
21Aplasia involving bones of the extremities (HP:0009825)3.12992321
22Aplasia involving bones of the upper limbs (HP:0009823)3.12992321
23Aplasia of the phalanges of the hand (HP:0009802)3.12992321
24Impaired vibration sensation in the lower limbs (HP:0002166)3.11352165
25Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.09180208
26Degeneration of the lateral corticospinal tracts (HP:0002314)3.09180208
27Agitation (HP:0000713)3.06251480
28Male infertility (HP:0003251)3.03931877
29Abnormality of dentin (HP:0010299)3.02393648
30Focal motor seizures (HP:0011153)2.99474063
31Lissencephaly (HP:0001339)2.96965901
32Dialeptic seizures (HP:0011146)2.93344172
33Sudden death (HP:0001699)2.89767387
34Febrile seizures (HP:0002373)2.79879564
35Wrist flexion contracture (HP:0001239)2.79452488
36Pachygyria (HP:0001302)2.78090990
37Abnormality of the lower motor neuron (HP:0002366)2.77003846
38Adrenal hypoplasia (HP:0000835)2.76074569
39Broad-based gait (HP:0002136)2.74307818
40Spastic tetraplegia (HP:0002510)2.72982766
41Atonic seizures (HP:0010819)2.71981678
42Myotonia (HP:0002486)2.70625085
43Impaired pain sensation (HP:0007328)2.70149057
44Abnormality of pain sensation (HP:0010832)2.70149057
45Curly hair (HP:0002212)2.69154712
46Abnormal hair whorl (HP:0010721)2.68195669
47True hermaphroditism (HP:0010459)2.66719585
48Epileptic encephalopathy (HP:0200134)2.64833934
49Hypothermia (HP:0002045)2.61491093
50Protrusio acetabuli (HP:0003179)2.60655815
51Polymicrogyria (HP:0002126)2.60634714
52Progressive inability to walk (HP:0002505)2.57541320
53Overgrowth (HP:0001548)2.55142905
54Tubulointerstitial fibrosis (HP:0005576)2.54606992
55Urinary urgency (HP:0000012)2.53187892
56Urinary bladder sphincter dysfunction (HP:0002839)2.52161062
57Tubulointerstitial abnormality (HP:0001969)2.51034962
58Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.50121268
59Hypoventilation (HP:0002791)2.49516364
60Premature rupture of membranes (HP:0001788)2.49166472
61Peripheral hypomyelination (HP:0007182)2.47046340
62Papilledema (HP:0001085)2.46183309
63Hand muscle atrophy (HP:0009130)2.41246500
64Atrophy/Degeneration involving motor neurons (HP:0007373)2.40558114
65Dysdiadochokinesis (HP:0002075)2.40213457
66Bradycardia (HP:0001662)2.37442241
67Morphological abnormality of the pyramidal tract (HP:0002062)2.37392453
68Inability to walk (HP:0002540)2.34701305
69Atrial fibrillation (HP:0005110)2.32260666
70Pancreatic fibrosis (HP:0100732)2.31396215
71Nuclear cataract (HP:0100018)2.26435817
72Rimmed vacuoles (HP:0003805)2.25196869
73Hypsarrhythmia (HP:0002521)2.23561727
74Papillary thyroid carcinoma (HP:0002895)2.23200803
75Severe Myopia (HP:0011003)2.23018193
76Focal seizures (HP:0007359)2.23000734
77Abnormality of the labia minora (HP:0012880)2.21563504
78Abnormality of salivation (HP:0100755)2.21501047
79Fibular aplasia (HP:0002990)2.20604850
80Primary atrial arrhythmia (HP:0001692)2.19788157
81Action tremor (HP:0002345)2.19530419
82Breast aplasia (HP:0100783)2.19245980
83Vascular tortuosity (HP:0004948)2.19067229
84EEG with generalized epileptiform discharges (HP:0011198)2.17952672
85Arterial tortuosity (HP:0005116)2.17934765
86Gait imbalance (HP:0002141)2.17196066
87Thyroid carcinoma (HP:0002890)2.10819276
88Epileptiform EEG discharges (HP:0011182)2.10163201
89Autoamputation (HP:0001218)2.09929263
90Torticollis (HP:0000473)2.09576956
91Shallow orbits (HP:0000586)2.08689236
92Progressive cerebellar ataxia (HP:0002073)2.08454854
93Spastic gait (HP:0002064)2.08323807
94Sleep apnea (HP:0010535)2.07810945
95Fetal akinesia sequence (HP:0001989)2.07616762
96Intention tremor (HP:0002080)2.06954914
97Prostate neoplasm (HP:0100787)2.02749943
98Hyperventilation (HP:0002883)2.01375464
99Hemiparesis (HP:0001269)1.99640097
100Lower limb muscle weakness (HP:0007340)1.99613737
101Inappropriate behavior (HP:0000719)1.99455004
102Abnormality of incisor morphology (HP:0011063)1.99304602
103Congenital primary aphakia (HP:0007707)1.99113104
104Aplasia/Hypoplasia of the breasts (HP:0010311)1.96626366
105Supraventricular tachycardia (HP:0004755)1.96521154
106Abnormal eating behavior (HP:0100738)1.95104043
107Neoplasm of the heart (HP:0100544)1.93203717
108Supranuclear gaze palsy (HP:0000605)1.92707642
109Bronchomalacia (HP:0002780)1.91350910
110Flat capital femoral epiphysis (HP:0003370)1.90106770
111Abnormal pancreas size (HP:0012094)1.90026186
112Abnormality of the motor neurons (HP:0002450)1.89936057
113Abnormal neuron morphology (HP:0012757)1.89936057
114Abnormality of the aortic arch (HP:0012303)1.89577085
115Supraventricular arrhythmia (HP:0005115)1.89546455
116Broad distal phalanx of finger (HP:0009836)1.88763753
117Generalized tonic-clonic seizures (HP:0002069)1.87027512
118Delusions (HP:0000746)1.85796573
119Hypoplasia of the corpus callosum (HP:0002079)1.85374308
120Increased connective tissue (HP:0009025)1.85348554
121Broad face (HP:0000283)1.84140614
122Bony spicule pigmentary retinopathy (HP:0007737)1.82718282
123Postaxial foot polydactyly (HP:0001830)1.81578047
124Neoplasm of the peripheral nervous system (HP:0100007)1.81261578
125Erectile abnormalities (HP:0100639)1.80920536
126Pulmonic stenosis (HP:0001642)1.80714081
127Anosmia (HP:0000458)1.80624304
128Genital tract atresia (HP:0001827)1.80004064
129Foot dorsiflexor weakness (HP:0009027)1.79375295
130Hypophosphatemic rickets (HP:0004912)1.78695236
131Impaired vibratory sensation (HP:0002495)1.78397307
132Prolonged QT interval (HP:0001657)1.76971573
133Gaze-evoked nystagmus (HP:0000640)1.76623756
134Narrow nasal bridge (HP:0000446)1.76501059
135Vaginal atresia (HP:0000148)1.75261208
136Barrel-shaped chest (HP:0001552)1.75069071
137Muscular hypotonia of the trunk (HP:0008936)1.74338307
138Bicornuate uterus (HP:0000813)1.74288691
139Pancreatic cysts (HP:0001737)1.74285188
140Male pseudohermaphroditism (HP:0000037)1.73858001
141Ulnar claw (HP:0001178)1.73226422
142Poor coordination (HP:0002370)1.72808609
143Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.72748885
144Micropenis (HP:0000054)1.72382585
145Genu recurvatum (HP:0002816)1.71968997
146Pheochromocytoma (HP:0002666)1.71580460
147Microglossia (HP:0000171)1.71507753
148Achilles tendon contracture (HP:0001771)1.71151597
149Abnormal respiratory motile cilium morphology (HP:0005938)1.70960985
150Abnormal respiratory epithelium morphology (HP:0012253)1.70960985
151Insidious onset (HP:0003587)1.70901930
152Termporal pattern (HP:0011008)1.70901930
153Intestinal atresia (HP:0011100)1.70410379
154Chromosomal breakage induced by crosslinking agents (HP:0003221)1.70351923
155Broad finger (HP:0001500)1.70019284
156Ankle contracture (HP:0006466)1.69456450
157Broad long bones (HP:0005622)1.69437046
158Steppage gait (HP:0003376)1.67570042
159Failure to thrive in infancy (HP:0001531)1.67480410
160Retinal dysplasia (HP:0007973)1.67385495
161Tracheomalacia (HP:0002779)1.67171166
162Nephrogenic diabetes insipidus (HP:0009806)1.66408934
163Left ventricular hypertrophy (HP:0001712)1.65747860
164Primary amenorrhea (HP:0000786)1.63151212
165Craniofacial dystonia (HP:0012179)1.61999416
166Chromsome breakage (HP:0040012)1.61152367
167Anxiety (HP:0000739)1.60643387
168Tubulointerstitial nephritis (HP:0001970)1.60106653
169Broad thumb (HP:0011304)1.59321206
170Focal dystonia (HP:0004373)1.58875848
171Broad foot (HP:0001769)1.58197714
172Absence seizures (HP:0002121)1.57680012
173Spondylolisthesis (HP:0003302)1.55509947
174Mitral regurgitation (HP:0001653)1.55446866
175Abnormality of the foot musculature (HP:0001436)1.54514955

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHB14.06361760
2STK38L3.69646527
3KSR23.64189285
4LATS23.63454295
5NTRK13.16195741
6DYRK33.04304771
7TRIM282.99449787
8BCR2.85448458
9EPHA32.78544195
10NTRK32.64274187
11ADRBK22.62352293
12LIMK12.43723244
13MAP3K122.33478837
14CAMKK22.33424276
15ERBB32.15984677
16ERBB42.04456139
17MOS2.02743742
18AKT32.01680943
19MAP3K91.99444257
20STK381.97126555
21UHMK11.96331445
22CASK1.96107020
23TAOK11.88401716
24WNK31.84841694
25MAPK131.82049699
26EPHB21.74898548
27ARAF1.73392991
28PAK61.71113013
29MAP2K71.69773754
30TRPM71.68709591
31LATS11.67565797
32PRKD31.67063834
33MUSK1.66861499
34EPHA41.66134393
35DYRK1B1.64277252
36DAPK21.61622772
37SIK31.57864927
38BRAF1.56314956
39TNK21.55238936
40MAP3K41.55154820
41MAP3K61.49008227
42MAPK151.42874700
43MINK11.41833079
44BMPR21.39882542
45FER1.37675900
46CDK191.35416161
47LMTK21.34243298
48MAP2K41.28121885
49MST41.26456899
50KSR11.25569661
51RPS6KA41.24559730
52PLK21.22486107
53SIK21.19631041
54CSNK1A1L1.18009890
55CSNK1G21.17543518
56TESK11.15425586
57EEF2K1.13507110
58GRK51.13233619
59RAF11.12870939
60MAP4K21.12514913
61RET1.12276211
62PNCK1.11094995
63OBSCN1.08378559
64CSNK1G31.06522008
65CAMK40.99741339
66MAP3K130.99642143
67DYRK1A0.96261302
68MATK0.96094920
69STK240.93454857
70MYLK0.91602850
71MAP3K20.91126758
72DDR20.90690161
73ROCK20.87295032
74NTRK20.86414098
75PAK30.86179186
76RIPK40.84855795
77WNK40.84606746
78CAMK1D0.83826010
79CDK80.82923109
80PLK40.82337683
81MARK10.81452181
82ROCK10.81199548
83PIK3CA0.80424328
84PTK2B0.80410477
85CSNK1G10.79364605
86CDK50.77735428
87MAP2K10.77178039
88SGK2230.77008080
89SGK4940.77008080
90MAP3K10.76109936
91LRRK20.76003058
92CAMK1G0.74755922
93CAMK2A0.74221946
94MARK20.72734138
95TAOK20.72703048
96TNIK0.70508249
97BMPR1B0.69113965
98PRKCG0.68660027
99CDK180.68468093
100FGR0.67180572
101PHKG20.66842790
102PHKG10.66842790
103CDK140.66707975
104PRKCE0.65947464
105CDK150.64416283
106PDGFRA0.63044937
107MAP3K80.60798214
108CAMK10.60629453
109DYRK20.59642333
110PRPF4B0.59174188
111PKN10.59108821
112PRKD20.58881063
113PRKAA10.58250914
114TTK0.55982748
115OXSR10.55605287
116SGK20.55393152
117AURKA0.55069323
118ADRBK10.53913191
119NEK10.53439919
120MAP3K50.53144987
121ABL20.51974600
122PIM20.50906247
123ILK0.50753611
124TAOK30.50665449
125PINK10.50044350
126STK30.49924995
127STK100.49744039
128CDK11A0.48091852
129SGK30.47483758
130MAPK90.46687845
131DAPK30.46217247
132INSRR0.43601873
133MELK0.43190167
134PRKG10.41872493
135VRK10.41351093
136MAP2K30.40244378
137PRKCZ0.39095229
138CHEK20.38819950
139CAMK2D0.37973697
140RIPK10.37924174
141TYRO30.36130550
142CAMKK10.36103046
143MAPKAPK50.35981299
144CDC42BPA0.35950232
145STK110.32693381
146PKN20.32247731
147RPS6KA20.31708316
148PRKACA0.30213718
149TESK20.29156867
150YES10.28188452
151RPS6KA50.28002553
152CSNK1A10.26797240
153EGFR0.26716708
154ERBB20.25033507
155SRPK10.24185296
156FYN0.23319155
157BCKDK0.22370010

Predicted pathways (KEGG)

RankGene SetZ-score
1Steroid biosynthesis_Homo sapiens_hsa001003.07093990
2Phototransduction_Homo sapiens_hsa047442.49817660
3Nicotine addiction_Homo sapiens_hsa050332.47225245
4Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.29386943
5GnRH signaling pathway_Homo sapiens_hsa049122.24387599
6Olfactory transduction_Homo sapiens_hsa047402.12833969
7Fatty acid elongation_Homo sapiens_hsa000622.12302448
8Pathogenic Escherichia coli infection_Homo sapiens_hsa051302.11812767
9Synaptic vesicle cycle_Homo sapiens_hsa047212.03339297
10Ovarian steroidogenesis_Homo sapiens_hsa049132.03041660
11Long-term depression_Homo sapiens_hsa047302.02438238
12Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.98905081
13Glutamatergic synapse_Homo sapiens_hsa047241.97774184
14Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.94365626
15Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.85878776
16Circadian entrainment_Homo sapiens_hsa047131.83379524
17Long-term potentiation_Homo sapiens_hsa047201.80882255
18GABAergic synapse_Homo sapiens_hsa047271.78115430
19Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.77050772
20Insulin secretion_Homo sapiens_hsa049111.77008582
21Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.75910027
22Serotonergic synapse_Homo sapiens_hsa047261.74950110
23Morphine addiction_Homo sapiens_hsa050321.69697675
24Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.68870080
25Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.67273646
26Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.67164462
27Oocyte meiosis_Homo sapiens_hsa041141.64312081
28Renin secretion_Homo sapiens_hsa049241.63754481
29Cholinergic synapse_Homo sapiens_hsa047251.61565329
30Dilated cardiomyopathy_Homo sapiens_hsa054141.60545630
31Gap junction_Homo sapiens_hsa045401.49956287
32Oxytocin signaling pathway_Homo sapiens_hsa049211.48361190
33Melanoma_Homo sapiens_hsa052181.47115069
34Thyroid cancer_Homo sapiens_hsa052161.46778756
35Cardiac muscle contraction_Homo sapiens_hsa042601.40371057
36Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.39676388
37Glioma_Homo sapiens_hsa052141.39613281
38Estrogen signaling pathway_Homo sapiens_hsa049151.39248839
39Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.38948348
40Dopaminergic synapse_Homo sapiens_hsa047281.37292643
41Gastric acid secretion_Homo sapiens_hsa049711.32469621
42Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.32016716
43Endometrial cancer_Homo sapiens_hsa052131.31774743
44Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.28774173
45Regulation of autophagy_Homo sapiens_hsa041401.28597893
46Phospholipase D signaling pathway_Homo sapiens_hsa040721.27429054
47Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.27074776
48Bladder cancer_Homo sapiens_hsa052191.26698141
49Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.20884118
50Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.19497685
51Type II diabetes mellitus_Homo sapiens_hsa049301.18457197
52VEGF signaling pathway_Homo sapiens_hsa043701.15616892
53Salivary secretion_Homo sapiens_hsa049701.15298259
54cAMP signaling pathway_Homo sapiens_hsa040241.12828879
55Parkinsons disease_Homo sapiens_hsa050121.10070840
56ErbB signaling pathway_Homo sapiens_hsa040121.09878845
57Vascular smooth muscle contraction_Homo sapiens_hsa042701.09486414
58Axon guidance_Homo sapiens_hsa043601.09116676
59Amphetamine addiction_Homo sapiens_hsa050311.08373948
60Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.08305178
61Alcoholism_Homo sapiens_hsa050341.07832016
62Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.07520243
63Cocaine addiction_Homo sapiens_hsa050301.07315887
64Taste transduction_Homo sapiens_hsa047421.05103298
65Aldosterone synthesis and secretion_Homo sapiens_hsa049251.03607115
66Oxidative phosphorylation_Homo sapiens_hsa001901.03419032
67Melanogenesis_Homo sapiens_hsa049161.02736252
68MAPK signaling pathway_Homo sapiens_hsa040101.01850410
69Choline metabolism in cancer_Homo sapiens_hsa052311.00124519
70Ras signaling pathway_Homo sapiens_hsa040140.99671185
71Sphingolipid signaling pathway_Homo sapiens_hsa040710.99035541
72Rap1 signaling pathway_Homo sapiens_hsa040150.98742148
73Prolactin signaling pathway_Homo sapiens_hsa049170.96101752
74Circadian rhythm_Homo sapiens_hsa047100.95460064
75Fatty acid biosynthesis_Homo sapiens_hsa000610.93085029
76Calcium signaling pathway_Homo sapiens_hsa040200.90972086
77Regulation of actin cytoskeleton_Homo sapiens_hsa048100.89936569
78Colorectal cancer_Homo sapiens_hsa052100.89331793
79Cell cycle_Homo sapiens_hsa041100.89155776
80Fatty acid metabolism_Homo sapiens_hsa012120.86588286
81RNA degradation_Homo sapiens_hsa030180.86285036
82Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.86189821
83Central carbon metabolism in cancer_Homo sapiens_hsa052300.85363893
84Pancreatic cancer_Homo sapiens_hsa052120.85101015
85Non-small cell lung cancer_Homo sapiens_hsa052230.84289782
86Phagosome_Homo sapiens_hsa041450.83166212
87Neurotrophin signaling pathway_Homo sapiens_hsa047220.82314972
88Dorso-ventral axis formation_Homo sapiens_hsa043200.80904585
89Maturity onset diabetes of the young_Homo sapiens_hsa049500.79080719
90Collecting duct acid secretion_Homo sapiens_hsa049660.77429428
91TGF-beta signaling pathway_Homo sapiens_hsa043500.76063967
92Protein export_Homo sapiens_hsa030600.75849118
93Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.75750084
94FoxO signaling pathway_Homo sapiens_hsa040680.75363929
95cGMP-PKG signaling pathway_Homo sapiens_hsa040220.74850199
96Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.74523650
97Renal cell carcinoma_Homo sapiens_hsa052110.74503375
98Hippo signaling pathway_Homo sapiens_hsa043900.73805302
99Sphingolipid metabolism_Homo sapiens_hsa006000.73600478
100Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.71388571
101Huntingtons disease_Homo sapiens_hsa050160.68425955
102Vibrio cholerae infection_Homo sapiens_hsa051100.67458767
103MicroRNAs in cancer_Homo sapiens_hsa052060.66132482
104Renin-angiotensin system_Homo sapiens_hsa046140.66036793
105Tight junction_Homo sapiens_hsa045300.65725176
106Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.60718615
107Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.60624118
108Ether lipid metabolism_Homo sapiens_hsa005650.57697315
109Alzheimers disease_Homo sapiens_hsa050100.57688831
110Endocytosis_Homo sapiens_hsa041440.56705576
111Basal transcription factors_Homo sapiens_hsa030220.55706517
112Shigellosis_Homo sapiens_hsa051310.54420142
113Proteoglycans in cancer_Homo sapiens_hsa052050.54149929
114Focal adhesion_Homo sapiens_hsa045100.53774056
115Platelet activation_Homo sapiens_hsa046110.53315257
116Hedgehog signaling pathway_Homo sapiens_hsa043400.52025312
117Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.51932867
118AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.51623538
119Adherens junction_Homo sapiens_hsa045200.51552301
120Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.51496822
121Salmonella infection_Homo sapiens_hsa051320.49949652
122Glucagon signaling pathway_Homo sapiens_hsa049220.49107627
123Steroid hormone biosynthesis_Homo sapiens_hsa001400.49101476
124Butanoate metabolism_Homo sapiens_hsa006500.49051362
125Insulin signaling pathway_Homo sapiens_hsa049100.49003050
126mTOR signaling pathway_Homo sapiens_hsa041500.48791270
127Chronic myeloid leukemia_Homo sapiens_hsa052200.47876930
128Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.45861231
129Primary bile acid biosynthesis_Homo sapiens_hsa001200.43985968
130ABC transporters_Homo sapiens_hsa020100.43872044
131Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.43123927
132Thyroid hormone signaling pathway_Homo sapiens_hsa049190.43074239
133Phosphatidylinositol signaling system_Homo sapiens_hsa040700.42776634
134Longevity regulating pathway - mammal_Homo sapiens_hsa042110.42560701
135Pertussis_Homo sapiens_hsa051330.42474635
136Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.42210277
137Inositol phosphate metabolism_Homo sapiens_hsa005620.38992134
138Tryptophan metabolism_Homo sapiens_hsa003800.37499054
139Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.37449717
140Linoleic acid metabolism_Homo sapiens_hsa005910.34728706
141Basal cell carcinoma_Homo sapiens_hsa052170.34596861
142Thyroid hormone synthesis_Homo sapiens_hsa049180.30692763
143Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.30337376
144Propanoate metabolism_Homo sapiens_hsa006400.29808773
145AMPK signaling pathway_Homo sapiens_hsa041520.27388979
146Wnt signaling pathway_Homo sapiens_hsa043100.26771773
147SNARE interactions in vesicular transport_Homo sapiens_hsa041300.24558090

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