GPN3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1purine nucleobase biosynthetic process (GO:0009113)5.59760072
2nucleobase biosynthetic process (GO:0046112)5.38028483
3mitotic metaphase plate congression (GO:0007080)4.72832755
4mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.67833113
5formation of translation preinitiation complex (GO:0001731)4.53827300
6ribosome assembly (GO:0042255)4.48371505
7DNA replication checkpoint (GO:0000076)4.45172817
8ribosome biogenesis (GO:0042254)4.43800851
9establishment of integrated proviral latency (GO:0075713)4.42594504
10maturation of SSU-rRNA (GO:0030490)4.42247978
11DNA deamination (GO:0045006)4.29827053
12establishment of protein localization to mitochondrial membrane (GO:0090151)4.25653678
13proteasome assembly (GO:0043248)4.25528378
14DNA strand elongation involved in DNA replication (GO:0006271)4.21313682
15DNA replication initiation (GO:0006270)4.19032271
16ribonucleoprotein complex biogenesis (GO:0022613)4.08391192
17DNA strand elongation (GO:0022616)4.00638392
18rRNA modification (GO:0000154)4.00593057
19energy coupled proton transport, down electrochemical gradient (GO:0015985)4.00531814
20ATP synthesis coupled proton transport (GO:0015986)4.00531814
21transcription elongation from RNA polymerase III promoter (GO:0006385)3.97799529
22termination of RNA polymerase III transcription (GO:0006386)3.97799529
23protein localization to kinetochore (GO:0034501)3.97374624
24metaphase plate congression (GO:0051310)3.96163723
25telomere maintenance via semi-conservative replication (GO:0032201)3.93242172
26chaperone-mediated protein transport (GO:0072321)3.93084704
27cullin deneddylation (GO:0010388)3.92908880
28CENP-A containing nucleosome assembly (GO:0034080)3.88008797
29ribosomal small subunit assembly (GO:0000028)3.86528255
30ribosomal large subunit biogenesis (GO:0042273)3.82941231
31chromatin remodeling at centromere (GO:0031055)3.79310300
32folic acid metabolic process (GO:0046655)3.74886250
33anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.72354216
34rRNA processing (GO:0006364)3.72310956
35regulation of mitochondrial translation (GO:0070129)3.72120378
36protein deneddylation (GO:0000338)3.69902662
37regulation of spindle organization (GO:0090224)3.68334767
38regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.68042476
39negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.67522435
40spliceosomal snRNP assembly (GO:0000387)3.67469823
41DNA double-strand break processing (GO:0000729)3.66986065
42regulation of cellular amino acid metabolic process (GO:0006521)3.66909327
43regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.65344287
44exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.65286359
45mitotic nuclear envelope disassembly (GO:0007077)3.64053637
46positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.63088782
477-methylguanosine mRNA capping (GO:0006370)3.61506060
48ribosomal small subunit biogenesis (GO:0042274)3.60695590
49nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.60595599
50rRNA metabolic process (GO:0016072)3.59957716
51mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.57256970
52DNA replication-dependent nucleosome organization (GO:0034723)3.57199115
53DNA replication-dependent nucleosome assembly (GO:0006335)3.57199115
54RNA capping (GO:0036260)3.55998277
557-methylguanosine RNA capping (GO:0009452)3.55998277
56DNA replication-independent nucleosome organization (GO:0034724)3.55981571
57DNA replication-independent nucleosome assembly (GO:0006336)3.55981571
58telomere maintenance via recombination (GO:0000722)3.55950579
59establishment of viral latency (GO:0019043)3.52300904
60termination of RNA polymerase I transcription (GO:0006363)3.51710133
61protein localization to chromosome, centromeric region (GO:0071459)3.50880709
62pseudouridine synthesis (GO:0001522)3.50515627
63transcription elongation from RNA polymerase I promoter (GO:0006362)3.49328324
64regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.48735151
65transcription from RNA polymerase I promoter (GO:0006360)3.44445109
66DNA ligation (GO:0006266)3.44045101
67kinetochore assembly (GO:0051382)3.43104408
68signal transduction involved in cell cycle checkpoint (GO:0072395)3.41910527
69oxidative phosphorylation (GO:0006119)3.41711419
70kinetochore organization (GO:0051383)3.41071032
71DNA catabolic process, exonucleolytic (GO:0000738)3.38385717
72regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.36797652
73regulation of mitotic spindle checkpoint (GO:1903504)3.36797652
74regulation of ubiquitin-protein transferase activity (GO:0051438)3.36042695
75mitochondrial respiratory chain complex assembly (GO:0033108)3.35880323
76respiratory electron transport chain (GO:0022904)3.35763286
77establishment of chromosome localization (GO:0051303)3.35740670
78protein targeting to mitochondrion (GO:0006626)3.35537669
79negative regulation of ligase activity (GO:0051352)3.34846392
80negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.34846392
81mitotic recombination (GO:0006312)3.34290446
82membrane disassembly (GO:0030397)3.34165499
83nuclear envelope disassembly (GO:0051081)3.34165499
84protein complex biogenesis (GO:0070271)3.34117748
85mitochondrial respiratory chain complex I assembly (GO:0032981)3.32843755
86NADH dehydrogenase complex assembly (GO:0010257)3.32843755
87mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.32843755
88attachment of spindle microtubules to kinetochore (GO:0008608)3.32288033
89transcription-coupled nucleotide-excision repair (GO:0006283)3.30933473
90histone exchange (GO:0043486)3.30888541
91respiratory chain complex IV assembly (GO:0008535)3.30229609
92protein neddylation (GO:0045116)3.28958409
93translational initiation (GO:0006413)3.27458517
94telomere maintenance via telomere lengthening (GO:0010833)3.26847931
95electron transport chain (GO:0022900)3.26044325
96positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.25976903
97regulation of ligase activity (GO:0051340)3.25295166
98IMP biosynthetic process (GO:0006188)3.25128415
99nucleotide-excision repair, DNA gap filling (GO:0006297)3.23142141
100translational termination (GO:0006415)3.21742465
101rRNA methylation (GO:0031167)3.21297618
102mitotic sister chromatid segregation (GO:0000070)3.21158146
103spindle checkpoint (GO:0031577)3.20496949
104cellular component biogenesis (GO:0044085)3.20246940
105viral transcription (GO:0019083)3.19922981
106DNA unwinding involved in DNA replication (GO:0006268)3.18685231
107G1/S transition of mitotic cell cycle (GO:0000082)3.16607315
108cell cycle G1/S phase transition (GO:0044843)3.16607315
109non-recombinational repair (GO:0000726)3.15066770
110double-strand break repair via nonhomologous end joining (GO:0006303)3.15066770
111transcription initiation from RNA polymerase I promoter (GO:0006361)3.14801514
112maturation of 5.8S rRNA (GO:0000460)3.12662812
113negative regulation of chromosome segregation (GO:0051985)3.12335927
114regulation of mitotic spindle organization (GO:0060236)3.10457251
115negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.10271997
116negative regulation of sister chromatid segregation (GO:0033046)3.10271997
117negative regulation of mitotic sister chromatid separation (GO:2000816)3.10271997
118negative regulation of mitotic sister chromatid segregation (GO:0033048)3.10271997
119positive regulation of ligase activity (GO:0051351)3.09888215
120protein localization to mitochondrion (GO:0070585)3.09126389
121nuclear pore organization (GO:0006999)3.08177599
122DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.07047400
123establishment of protein localization to mitochondrion (GO:0072655)3.05880620
124mitotic spindle assembly checkpoint (GO:0007094)3.05764921
125spindle assembly checkpoint (GO:0071173)3.05126407
126signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.04916154
127signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.04916154
128signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.04916154
129mitotic spindle checkpoint (GO:0071174)3.04130292
130regulation of nuclear cell cycle DNA replication (GO:0033262)3.03565383
131spliceosomal complex assembly (GO:0000245)3.03417195
132signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.03196797
133intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.03196797
134signal transduction involved in DNA damage checkpoint (GO:0072422)3.02909626
135signal transduction involved in DNA integrity checkpoint (GO:0072401)3.02909626
136regulation of double-strand break repair via homologous recombination (GO:0010569)3.01786221
137positive regulation of chromosome segregation (GO:0051984)3.01486654
138negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.01297204
139translational elongation (GO:0006414)3.01254493
140IMP metabolic process (GO:0046040)3.00266456

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.80015666
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.29253741
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.77191106
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.58418114
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.41563948
6* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.40726810
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.38302330
8GABP_17652178_ChIP-ChIP_JURKAT_Human3.33654420
9E2F4_17652178_ChIP-ChIP_JURKAT_Human3.29986751
10ETS1_20019798_ChIP-Seq_JURKAT_Human3.24960220
11CREB1_15753290_ChIP-ChIP_HEK293T_Human3.19393917
12E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.19206558
13MYC_19079543_ChIP-ChIP_MESCs_Mouse3.07945265
14MYC_18358816_ChIP-ChIP_MESCs_Mouse3.00508390
15MYC_19030024_ChIP-ChIP_MESCs_Mouse2.91963941
16FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.84382611
17NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.58298857
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.55860637
19VDR_23849224_ChIP-Seq_CD4+_Human2.48271995
20NELFA_20434984_ChIP-Seq_ESCs_Mouse2.45682730
21HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.45439014
22MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.42166665
23* XRN2_22483619_ChIP-Seq_HELA_Human2.33454429
24E2F1_18555785_ChIP-Seq_MESCs_Mouse2.19663111
25HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.14379228
26DCP1A_22483619_ChIP-Seq_HELA_Human2.08550468
27CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.08003572
28* FOXP3_21729870_ChIP-Seq_TREG_Human2.06386100
29AR_21909140_ChIP-Seq_LNCAP_Human2.02698663
30GABP_19822575_ChIP-Seq_HepG2_Human2.02250963
31THAP11_20581084_ChIP-Seq_MESCs_Mouse2.00378365
32ELF1_17652178_ChIP-ChIP_JURKAT_Human2.00212746
33POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.97332601
34MYCN_18555785_ChIP-Seq_MESCs_Mouse1.94802310
35MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.93712857
36NANOG_18555785_ChIP-Seq_MESCs_Mouse1.92755776
37YY1_21170310_ChIP-Seq_MESCs_Mouse1.85658553
38PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.78772811
39TTF2_22483619_ChIP-Seq_HELA_Human1.77879798
40SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.69806369
41ELK1_19687146_ChIP-ChIP_HELA_Human1.69577211
42YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.67127686
43* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.65984881
44E2F1_21310950_ChIP-Seq_MCF-7_Human1.65839412
45SRF_21415370_ChIP-Seq_HL-1_Mouse1.64927533
46SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.64689876
47ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.60959033
48KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.54111129
49KDM5A_27292631_Chip-Seq_BREAST_Human1.50524135
50ZFX_18555785_ChIP-Seq_MESCs_Mouse1.48635822
51CIITA_25753668_ChIP-Seq_RAJI_Human1.47001308
52MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.46889624
53CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.46366609
54POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.45076345
55PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.44720778
56HOXB4_20404135_ChIP-ChIP_EML_Mouse1.42537825
57TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.37279577
58POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.32444947
59KLF4_18555785_ChIP-Seq_MESCs_Mouse1.26493169
60SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.26310346
61STAT3_1855785_ChIP-Seq_MESCs_Mouse1.25536875
62SALL1_21062744_ChIP-ChIP_HESCs_Human1.24742159
63HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.24319517
64NOTCH1_21737748_ChIP-Seq_TLL_Human1.24165529
65SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.23197793
66PADI4_21655091_ChIP-ChIP_MCF-7_Human1.22046070
67CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.20207099
68BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.17145326
69EWS_26573619_Chip-Seq_HEK293_Human1.16845743
70ERG_20887958_ChIP-Seq_HPC-7_Mouse1.16481074
71FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.16437710
72TFEB_21752829_ChIP-Seq_HELA_Human1.13096655
73VDR_22108803_ChIP-Seq_LS180_Human1.12700447
74ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.10169559
75ELK1_22589737_ChIP-Seq_MCF10A_Human1.09871748
76NANOG_16153702_ChIP-ChIP_HESCs_Human1.09081529
77SOX2_18555785_ChIP-Seq_MESCs_Mouse1.08494883
78EGR1_19374776_ChIP-ChIP_THP-1_Human1.08424323
79TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.06349034
80* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.05064188
81KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.02375221
82DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.01597727
83PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.01360703
84CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.99175774
85KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.99070718
86NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.97603853
87SOX17_20123909_ChIP-Seq_XEN_Mouse0.97555235
88CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.97224664
89KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.96974338
90KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.96974338
91KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.96974338
92ZNF274_21170338_ChIP-Seq_K562_Hela0.95868707
93CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95672840
94TP63_19390658_ChIP-ChIP_HaCaT_Human0.95486352
95ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.95016825
96* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.94543552
97MYC_22102868_ChIP-Seq_BL_Human0.94005733
98MYC_18940864_ChIP-ChIP_HL60_Human0.92860652
99SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.90342251
100FUS_26573619_Chip-Seq_HEK293_Human0.88905859
101SOX2_16153702_ChIP-ChIP_HESCs_Human0.88084359
102NANOG_21062744_ChIP-ChIP_HESCs_Human0.86626842
103OCT4_18692474_ChIP-Seq_MEFs_Mouse0.86486876
104SOX2_18692474_ChIP-Seq_MEFs_Mouse0.86233058
105TCF3_18692474_ChIP-Seq_MEFs_Mouse0.85921479
106NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.85303607
107HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.84668928
108CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.84282702
109SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.82651018
110NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.82198887
111POU5F1_16153702_ChIP-ChIP_HESCs_Human0.81575080
112DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.81278265
113CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.80269598
114IRF1_19129219_ChIP-ChIP_H3396_Human0.79411442
115CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.78992673
116ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.76174323
117FLI1_27457419_Chip-Seq_LIVER_Mouse0.75731852
118GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.73762716
119SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.69287694
120ELF5_23300383_ChIP-Seq_T47D_Human0.69054502
121RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.65351620
122IGF1R_20145208_ChIP-Seq_DFB_Human0.62613017
123TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.61663609

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching6.54603778
2MP0004957_abnormal_blastocyst_morpholog5.00425349
3MP0003111_abnormal_nucleus_morphology4.97185099
4MP0010094_abnormal_chromosome_stability4.73308290
5MP0003077_abnormal_cell_cycle4.19436275
6MP0008057_abnormal_DNA_replication4.13489040
7MP0008058_abnormal_DNA_repair3.76441240
8MP0009697_abnormal_copulation3.07861132
9MP0003718_maternal_effect2.89854412
10MP0008932_abnormal_embryonic_tissue2.83905687
11MP0008007_abnormal_cellular_replicative2.70215095
12MP0003786_premature_aging2.52121541
13MP0001730_embryonic_growth_arrest2.50956129
14MP0003806_abnormal_nucleotide_metabolis2.39617641
15MP0003123_paternal_imprinting2.39076442
16MP0002396_abnormal_hematopoietic_system2.22399808
17MP0000350_abnormal_cell_proliferation2.21851516
18MP0008877_abnormal_DNA_methylation2.16947875
19MP0000372_irregular_coat_pigmentation2.14043818
20MP0010307_abnormal_tumor_latency1.83769079
21MP0005380_embryogenesis_phenotype1.77689917
22MP0001672_abnormal_embryogenesis/_devel1.77689917
23MP0001697_abnormal_embryo_size1.69889380
24MP0008260_abnormal_autophagy1.68215330
25MP0006072_abnormal_retinal_apoptosis1.63839896
26MP0009333_abnormal_splenocyte_physiolog1.63716082
27MP0002080_prenatal_lethality1.61726439
28MP0001529_abnormal_vocalization1.60071905
29MP0000490_abnormal_crypts_of1.54956559
30MP0003984_embryonic_growth_retardation1.54410914
31MP0002088_abnormal_embryonic_growth/wei1.50235841
32MP0000313_abnormal_cell_death1.47402000
33MP0002102_abnormal_ear_morphology1.44925162
34MP0002938_white_spotting1.42429035
35MP0010352_gastrointestinal_tract_polyps1.38464567
36MP0003186_abnormal_redox_activity1.37812758
37MP0002210_abnormal_sex_determination1.37054352
38MP0002085_abnormal_embryonic_tissue1.36054077
39MP0002132_abnormal_respiratory_system1.34981730
40MP0003567_abnormal_fetal_cardiomyocyte1.33964444
41MP0002019_abnormal_tumor_incidence1.31610920
42MP0000749_muscle_degeneration1.31291874
43MP0003195_calcinosis1.29736338
44MP0006035_abnormal_mitochondrial_morpho1.29074127
45MP0000358_abnormal_cell_content/1.27057497
46MP0006036_abnormal_mitochondrial_physio1.26929938
47MP0006292_abnormal_olfactory_placode1.25078677
48MP0001145_abnormal_male_reproductive1.22859230
49MP0005397_hematopoietic_system_phenotyp1.22763568
50MP0001545_abnormal_hematopoietic_system1.22763568
51MP0002086_abnormal_extraembryonic_tissu1.22074592
52MP0008789_abnormal_olfactory_epithelium1.20231200
53MP0002084_abnormal_developmental_patter1.18229979
54MP0001929_abnormal_gametogenesis1.17013075
55MP0003315_abnormal_perineum_morphology1.15838343
56MP0003221_abnormal_cardiomyocyte_apopto1.15624356
57MP0005084_abnormal_gallbladder_morpholo1.11419892
58MP0004215_abnormal_myocardial_fiber1.11106352
59MP0004147_increased_porphyrin_level1.08302992
60MP0002837_dystrophic_cardiac_calcinosis1.07470582
61MP0000653_abnormal_sex_gland1.06098947
62MP0004197_abnormal_fetal_growth/weight/1.05958531
63MP0005075_abnormal_melanosome_morpholog1.02181353
64MP0005367_renal/urinary_system_phenotyp1.01018120
65MP0000516_abnormal_urinary_system1.01018120
66MP0004808_abnormal_hematopoietic_stem1.00973514
67MP0003937_abnormal_limbs/digits/tail_de0.99487775
68MP0002090_abnormal_vision0.98863890
69MP0001293_anophthalmia0.98548329
70MP0002736_abnormal_nociception_after0.98172902
71MP0002160_abnormal_reproductive_system0.97220906
72MP0002163_abnormal_gland_morphology0.95875644
73MP0009840_abnormal_foam_cell0.95475891
74MP0001764_abnormal_homeostasis0.92330767
75MP0001542_abnormal_bone_strength0.90317886
76MP0005389_reproductive_system_phenotype0.90182610
77MP0005377_hearing/vestibular/ear_phenot0.88990457
78MP0003878_abnormal_ear_physiology0.88990457
79MP0005384_cellular_phenotype0.88915973
80MP0005253_abnormal_eye_physiology0.88286658
81MP0002722_abnormal_immune_system0.87682650
82MP0003656_abnormal_erythrocyte_physiolo0.86222272
83MP0005330_cardiomyopathy0.85322683
84MP0005266_abnormal_metabolism0.84774245
85MP0002653_abnormal_ependyma_morphology0.84418421
86MP0001661_extended_life_span0.83945107
87MP0000703_abnormal_thymus_morphology0.83052909
88MP0000689_abnormal_spleen_morphology0.82927005
89MP0000647_abnormal_sebaceous_gland0.82497765
90MP0005395_other_phenotype0.81153896
91MP0005621_abnormal_cell_physiology0.80835362
92MP0000750_abnormal_muscle_regeneration0.80001086
93MP0004133_heterotaxia0.79440681
94MP0005408_hypopigmentation0.77396646
95MP0001119_abnormal_female_reproductive0.77240553
96MP0002398_abnormal_bone_marrow0.76821917
97MP0003763_abnormal_thymus_physiology0.76697877
98MP0009672_abnormal_birth_weight0.75651070
99MP0002234_abnormal_pharynx_morphology0.74039033
100MP0003941_abnormal_skin_development0.71962075
101MP0002233_abnormal_nose_morphology0.71959459
102MP0003136_yellow_coat_color0.70314674
103MP0003119_abnormal_digestive_system0.69300260
104MP0003121_genomic_imprinting0.67762980
105MP0005394_taste/olfaction_phenotype0.67726854
106MP0005499_abnormal_olfactory_system0.67726854
107MP0008995_early_reproductive_senescence0.67633662
108MP0005332_abnormal_amino_acid0.67107434
109MP0002429_abnormal_blood_cell0.65496412
110MP0001919_abnormal_reproductive_system0.65245178
111MP0005410_abnormal_fertilization0.64597840
112MP0003646_muscle_fatigue0.64280151
113MP0001286_abnormal_eye_development0.63811541
114MP0003890_abnormal_embryonic-extraembry0.63456826
115MP0001346_abnormal_lacrimal_gland0.63363387
116MP0005379_endocrine/exocrine_gland_phen0.62527286
117MP0003698_abnormal_male_reproductive0.61038190
118MP0003011_delayed_dark_adaptation0.59808846
119MP0008873_increased_physiological_sensi0.59564406
120MP0002161_abnormal_fertility/fecundity0.57573029
121MP0002111_abnormal_tail_morphology0.56739956
122MP0008872_abnormal_physiological_respon0.56658947
123MP0004084_abnormal_cardiac_muscle0.56632946
124MP0002095_abnormal_skin_pigmentation0.56021493
125MP0004145_abnormal_muscle_electrophysio0.55736664
126MP0003699_abnormal_female_reproductive0.55536414
127MP0004264_abnormal_extraembryonic_tissu0.54733661
128MP0003936_abnormal_reproductive_system0.54660923
129MP0003938_abnormal_ear_development0.54250426
130MP0001853_heart_inflammation0.53682763
131MP0010030_abnormal_orbit_morphology0.53513474
132MP0009703_decreased_birth_body0.53369617
133MP0001849_ear_inflammation0.50683236
134MP0004381_abnormal_hair_follicle0.50335692
135MP0000477_abnormal_intestine_morphology0.49291821
136MP0001727_abnormal_embryo_implantation0.48895172
137MP0002269_muscular_atrophy0.48166043

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)6.03219288
2Breast hypoplasia (HP:0003187)5.03617313
3Acute necrotizing encephalopathy (HP:0006965)4.86961749
4Acute encephalopathy (HP:0006846)4.55659974
5Abnormal mitochondria in muscle tissue (HP:0008316)4.49501207
6Mitochondrial inheritance (HP:0001427)4.31351711
7Cerebral hypomyelination (HP:0006808)4.19689151
8Progressive macrocephaly (HP:0004481)4.16210212
9Abnormality of cells of the erythroid lineage (HP:0012130)4.09123369
10Abnormal number of erythroid precursors (HP:0012131)4.02668479
11Carpal bone hypoplasia (HP:0001498)4.02624914
12Increased hepatocellular lipid droplets (HP:0006565)3.95468833
13Rough bone trabeculation (HP:0100670)3.93234039
14Hepatic necrosis (HP:0002605)3.85612272
15Lipid accumulation in hepatocytes (HP:0006561)3.71208554
16Cerebral edema (HP:0002181)3.51371549
17Oral leukoplakia (HP:0002745)3.51300105
18Reticulocytopenia (HP:0001896)3.48019342
19Patellar aplasia (HP:0006443)3.47952547
20Aplasia/Hypoplasia of the patella (HP:0006498)3.35601688
21Abnormality of the anterior horn cell (HP:0006802)3.31238095
22Degeneration of anterior horn cells (HP:0002398)3.31238095
23Renal Fanconi syndrome (HP:0001994)3.27879735
24Impulsivity (HP:0100710)3.26736219
25Macrocytic anemia (HP:0001972)3.10104548
26Multiple enchondromatosis (HP:0005701)2.99368049
27Lactic acidosis (HP:0003128)2.97809194
28Abnormal trabecular bone morphology (HP:0100671)2.97004922
29Meckel diverticulum (HP:0002245)2.94362600
30Chromsome breakage (HP:0040012)2.93660758
31Abnormality of the preputium (HP:0100587)2.93297894
32Abnormality of the labia minora (HP:0012880)2.91974611
33Chromosomal breakage induced by crosslinking agents (HP:0003221)2.90678601
34Abnormality of methionine metabolism (HP:0010901)2.89810908
35Absent radius (HP:0003974)2.87912177
36Colon cancer (HP:0003003)2.85983890
37Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.85347072
38Increased intramyocellular lipid droplets (HP:0012240)2.82691944
39Abnormality of the ileum (HP:0001549)2.82075062
40Premature ovarian failure (HP:0008209)2.81217305
41Aplastic anemia (HP:0001915)2.77912326
42Progressive muscle weakness (HP:0003323)2.76002316
43Selective tooth agenesis (HP:0001592)2.74730602
44Exercise intolerance (HP:0003546)2.74381382
45Secondary amenorrhea (HP:0000869)2.71993972
46Respiratory failure (HP:0002878)2.70512602
47Abnormality of chromosome stability (HP:0003220)2.70345050
48Aplasia involving forearm bones (HP:0009822)2.66022790
49Absent forearm bone (HP:0003953)2.66022790
50Ependymoma (HP:0002888)2.60180913
51CNS hypomyelination (HP:0003429)2.58743404
52Microretrognathia (HP:0000308)2.56605548
53Methylmalonic acidemia (HP:0002912)2.53720528
54Bone marrow hypocellularity (HP:0005528)2.53022633
55Supernumerary spleens (HP:0009799)2.50918247
56Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.47654053
57Abnormal protein N-linked glycosylation (HP:0012347)2.47654053
58Abnormal protein glycosylation (HP:0012346)2.47654053
59Abnormal glycosylation (HP:0012345)2.47654053
60Reduced antithrombin III activity (HP:0001976)2.45265411
61Pallor (HP:0000980)2.44695849
62Hyperglycinemia (HP:0002154)2.43217902
63Increased serum lactate (HP:0002151)2.42392619
64Trismus (HP:0000211)2.42308756
65Hypoplasia of the capital femoral epiphysis (HP:0003090)2.40999664
66Increased serum pyruvate (HP:0003542)2.40023866
67Abnormality of glycolysis (HP:0004366)2.40023866
68Agnosia (HP:0010524)2.39436982
69Abnormality of the umbilical cord (HP:0010881)2.38815541
70Absent thumb (HP:0009777)2.38691946
71Exertional dyspnea (HP:0002875)2.38197476
72Irregular epiphyses (HP:0010582)2.37797326
73Increased muscle lipid content (HP:0009058)2.37180641
74Aplasia/Hypoplasia of the uvula (HP:0010293)2.35985725
75Abnormality of aspartate family amino acid metabolism (HP:0010899)2.35963674
763-Methylglutaconic aciduria (HP:0003535)2.34358490
77Premature graying of hair (HP:0002216)2.33838666
78Sparse eyelashes (HP:0000653)2.33381515
79Duodenal stenosis (HP:0100867)2.32009352
80Small intestinal stenosis (HP:0012848)2.32009352
81Horseshoe kidney (HP:0000085)2.31967146
82Abnormal spermatogenesis (HP:0008669)2.30891132
83Megaloblastic anemia (HP:0001889)2.30779657
84Ureteral duplication (HP:0000073)2.30414328
85Abnormality of the heme biosynthetic pathway (HP:0010472)2.28752017
86Leukodystrophy (HP:0002415)2.28059219
87Neoplasm of the pancreas (HP:0002894)2.26345555
88Methylmalonic aciduria (HP:0012120)2.23507485
89Myelodysplasia (HP:0002863)2.23419701
90Lethargy (HP:0001254)2.22758959
91Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.18727221
92Abnormality of alanine metabolism (HP:0010916)2.18727221
93Hyperalaninemia (HP:0003348)2.18727221
94Decreased activity of mitochondrial respiratory chain (HP:0008972)2.16525920
95Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.16525920
96Cellular immunodeficiency (HP:0005374)2.14603177
97Abnormality of serum amino acid levels (HP:0003112)2.13647531
98Microvesicular hepatic steatosis (HP:0001414)2.09458135
99Glossoptosis (HP:0000162)2.08822513
100Optic disc pallor (HP:0000543)2.07975879
101Neoplasm of the adrenal gland (HP:0100631)2.06212280
102Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.05658549
103Medulloblastoma (HP:0002885)2.04084751
104Death in infancy (HP:0001522)2.04052231
105Sloping forehead (HP:0000340)2.03746537
106Atrophy/Degeneration involving motor neurons (HP:0007373)2.01313194
107Increased CSF lactate (HP:0002490)1.99540387
108Pancytopenia (HP:0001876)1.98378198
109Cleft eyelid (HP:0000625)1.97772931
110Hepatocellular necrosis (HP:0001404)1.94533275
111Entropion (HP:0000621)1.94249847
112Nephroblastoma (Wilms tumor) (HP:0002667)1.93405650
113Postnatal microcephaly (HP:0005484)1.92371505
114Areflexia of lower limbs (HP:0002522)1.92076554
115Triphalangeal thumb (HP:0001199)1.90915065
116Respiratory difficulties (HP:0002880)1.90766210
117Aplasia/Hypoplasia of the sacrum (HP:0008517)1.90160065
118Embryonal renal neoplasm (HP:0011794)1.89516827
119Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.89224730
120Abnormality of renal resorption (HP:0011038)1.89026745
121Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.88151577
122Absent epiphyses (HP:0010577)1.88151577
123Muscle fiber atrophy (HP:0100295)1.87939988
124Hypoplasia of the radius (HP:0002984)1.87934100
125CNS demyelination (HP:0007305)1.87617396
126Rhabdomyosarcoma (HP:0002859)1.87063712
12711 pairs of ribs (HP:0000878)1.86945591
128Abnormality of the duodenum (HP:0002246)1.85092135
129Type I transferrin isoform profile (HP:0003642)1.84967072
130Aplasia/Hypoplasia involving the musculature (HP:0001460)1.83332440
131Neoplasm of the colon (HP:0100273)1.82878633
132Abnormal lung lobation (HP:0002101)1.82575652
133Delusions (HP:0000746)1.81897317
134Atresia of the external auditory canal (HP:0000413)1.80828681
135Amniotic constriction ring (HP:0009775)1.78780171
136Abnormality of placental membranes (HP:0011409)1.78780171
137Clubbing of toes (HP:0100760)1.73702812
138Abnormality of sulfur amino acid metabolism (HP:0004339)1.73421664
139Emotional lability (HP:0000712)1.72510954
140Hypoplastic pelvis (HP:0008839)1.69303340
141Hyperglycinuria (HP:0003108)1.69136833
142Abnormality of the carotid arteries (HP:0005344)1.66287868
143Nausea (HP:0002018)1.65944056
144Congenital, generalized hypertrichosis (HP:0004540)1.65573475
145Abnormality of serine family amino acid metabolism (HP:0010894)1.65431995
146Abnormality of glycine metabolism (HP:0010895)1.65431995

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB16.21640290
2WEE14.95979087
3VRK23.53776344
4EIF2AK13.23463541
5TSSK63.07781107
6CDC72.80162598
7STK162.77951806
8SRPK12.75615883
9BRSK22.75061245
10PLK42.74097171
11NME22.58539796
12NEK22.58116457
13ACVR1B2.17920193
14NEK12.14332776
15TTK2.12480149
16TRIM282.09404221
17VRK12.06866159
18PLK12.06617997
19EIF2AK32.04474767
20EPHA21.98570147
21PLK31.94553450
22NUAK11.90252632
23DYRK31.79537234
24AKT31.75796140
25BRSK11.73659837
26CCNB11.58351641
27AURKB1.58310257
28TESK21.58062169
29ERBB31.51683906
30CDK71.47401484
31ZAK1.44828856
32CHEK21.38215369
33AURKA1.34604092
34MKNK11.33279319
35TLK11.26767852
36ATR1.24724444
37PIM21.22420179
38RPS6KB21.13096416
39WNK31.11164061
40TAF11.10370346
41MAP3K121.09244255
42RPS6KA41.05829012
43CHEK11.05041501
44BRAF1.04821029
45BMPR1B1.00580765
46MAP3K80.99889736
47NME10.99219944
48PDK40.98486299
49PDK30.98486299
50CDK40.98042965
51MKNK20.96904404
52MAP4K20.96660261
53PASK0.95756647
54PLK20.91147467
55PNCK0.85793364
56LIMK10.85344543
57TNIK0.84581413
58DAPK10.80326979
59STK40.80109010
60SCYL20.79992502
61STK100.79303634
62PAK40.78721981
63PIM10.77815014
64BCR0.77547448
65BCKDK0.76067486
66EIF2AK20.75650416
67PBK0.74618602
68CSNK2A20.73993994
69CSNK2A10.71535072
70PDK20.71292994
71CDK20.70996495
72OBSCN0.67529624
73PAK10.67409412
74PRKCI0.65160926
75CSNK1G20.64364557
76ATM0.63503533
77OXSR10.61043397
78MAP2K30.61014508
79KDR0.55540807
80STK38L0.55463608
81ARAF0.54803640
82FRK0.54649407
83RPS6KA50.54287494
84STK30.52530386
85CDK10.51604677
86CSNK1A1L0.51557827
87STK240.50884954
88DYRK20.49740643
89ERBB40.49278900
90MAP2K70.48206161
91TGFBR10.48146271
92MST40.46923660
93MAP3K110.46463093
94CDK120.45298211
95CDK80.45256698
96ALK0.42301024
97GRK10.42232481
98MARK30.41806564
99MAP3K30.40186798
100MAPKAPK50.39084915
101STK390.37919021
102CSNK1G30.36951941
103MAP4K10.36187014
104ABL20.35415859
105PINK10.35133168
106CSNK1E0.34429066
107MELK0.33473238
108CDK190.29920345
109MYLK0.27721996
110IRAK30.27413578
111TESK10.27088240
112PHKG10.27047107
113PHKG20.27047107
114MINK10.26867844
115MAP3K40.25971663
116TAOK20.24514468
117MAPKAPK30.22344439
118AKT20.22174935
119FLT30.20768756
120PRKDC0.17247937
121CDK30.16481630
122CDK60.16175525
123LRRK20.16138077
124RAF10.15436844
125CSNK1G10.12253265
126MAP2K20.11002186
127BRD40.10724191
128LATS20.10069520
129ILK0.09997302

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.27114920
2RNA polymerase_Homo sapiens_hsa030204.22694177
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.13378491
4Proteasome_Homo sapiens_hsa030503.99368048
5Mismatch repair_Homo sapiens_hsa034303.67292891
6Ribosome_Homo sapiens_hsa030103.49119305
7RNA transport_Homo sapiens_hsa030133.19843159
8Spliceosome_Homo sapiens_hsa030403.10112281
9Vitamin B6 metabolism_Homo sapiens_hsa007502.93784252
10Homologous recombination_Homo sapiens_hsa034402.78725878
11Pyrimidine metabolism_Homo sapiens_hsa002402.70852652
12Base excision repair_Homo sapiens_hsa034102.67586496
13Nucleotide excision repair_Homo sapiens_hsa034202.65843457
14Cell cycle_Homo sapiens_hsa041102.50047923
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.31392535
16Basal transcription factors_Homo sapiens_hsa030222.17519473
17One carbon pool by folate_Homo sapiens_hsa006702.07574909
18Fanconi anemia pathway_Homo sapiens_hsa034601.98848137
19Non-homologous end-joining_Homo sapiens_hsa034501.77522058
20Propanoate metabolism_Homo sapiens_hsa006401.67269224
21RNA degradation_Homo sapiens_hsa030181.65529921
22Fatty acid elongation_Homo sapiens_hsa000621.64034641
23Folate biosynthesis_Homo sapiens_hsa007901.63038682
24p53 signaling pathway_Homo sapiens_hsa041151.59674746
25Purine metabolism_Homo sapiens_hsa002301.56756786
26Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.41050118
27mRNA surveillance pathway_Homo sapiens_hsa030151.37597977
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.27011229
29Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.25302529
30Pentose phosphate pathway_Homo sapiens_hsa000301.24556105
31Epstein-Barr virus infection_Homo sapiens_hsa051691.21322284
32Cysteine and methionine metabolism_Homo sapiens_hsa002701.15413277
33Drug metabolism - other enzymes_Homo sapiens_hsa009831.07259952
34Biosynthesis of amino acids_Homo sapiens_hsa012301.05874214
35Regulation of autophagy_Homo sapiens_hsa041401.03314754
36Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.01677188
37Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.01642720
38Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.00937627
39Huntingtons disease_Homo sapiens_hsa050160.99529600
40Protein export_Homo sapiens_hsa030600.98970855
41Sulfur metabolism_Homo sapiens_hsa009200.98513545
42Parkinsons disease_Homo sapiens_hsa050120.94907460
43Oocyte meiosis_Homo sapiens_hsa041140.94865726
44Oxidative phosphorylation_Homo sapiens_hsa001900.92249980
45Sulfur relay system_Homo sapiens_hsa041220.90397423
46Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.88547071
47Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.84311111
48Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.82302406
49Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.77305783
50Selenocompound metabolism_Homo sapiens_hsa004500.77253951
51Peroxisome_Homo sapiens_hsa041460.77194899
52Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.76649653
53Carbon metabolism_Homo sapiens_hsa012000.74660229
542-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.74530369
55Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.72091110
56Systemic lupus erythematosus_Homo sapiens_hsa053220.71530764
57Steroid biosynthesis_Homo sapiens_hsa001000.70943515
58Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.68751518
59Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.68597999
60Glutathione metabolism_Homo sapiens_hsa004800.68585886
61Fructose and mannose metabolism_Homo sapiens_hsa000510.66580716
62Antigen processing and presentation_Homo sapiens_hsa046120.64952413
63Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.62904901
64Viral carcinogenesis_Homo sapiens_hsa052030.62134042
65Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.59688653
66Fatty acid metabolism_Homo sapiens_hsa012120.57417221
67Herpes simplex infection_Homo sapiens_hsa051680.55494775
68Cyanoamino acid metabolism_Homo sapiens_hsa004600.52284531
69Metabolic pathways_Homo sapiens_hsa011000.51983672
70Butanoate metabolism_Homo sapiens_hsa006500.49285072
71Fatty acid degradation_Homo sapiens_hsa000710.44677727
72Pentose and glucuronate interconversions_Homo sapiens_hsa000400.43733524
73Vitamin digestion and absorption_Homo sapiens_hsa049770.40913495
74Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.39863868
75Phototransduction_Homo sapiens_hsa047440.38618469
76beta-Alanine metabolism_Homo sapiens_hsa004100.34843122
77HTLV-I infection_Homo sapiens_hsa051660.33965522
78Glycerophospholipid metabolism_Homo sapiens_hsa005640.33814421
79Tryptophan metabolism_Homo sapiens_hsa003800.33604935
80Galactose metabolism_Homo sapiens_hsa000520.33127105
81Collecting duct acid secretion_Homo sapiens_hsa049660.32637159
82Primary bile acid biosynthesis_Homo sapiens_hsa001200.30248837
83Alzheimers disease_Homo sapiens_hsa050100.29201031
84Legionellosis_Homo sapiens_hsa051340.27991613
85Primary immunodeficiency_Homo sapiens_hsa053400.27545471
86Thyroid cancer_Homo sapiens_hsa052160.27396484
87Arginine and proline metabolism_Homo sapiens_hsa003300.27003709
88Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.26234449
89Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.24768202
90Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.24416769
91SNARE interactions in vesicular transport_Homo sapiens_hsa041300.23268060
92Renin-angiotensin system_Homo sapiens_hsa046140.21890217
93Tyrosine metabolism_Homo sapiens_hsa003500.20638181
94Arachidonic acid metabolism_Homo sapiens_hsa005900.20250814
95Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.18913694
96Apoptosis_Homo sapiens_hsa042100.15535176
97Pyruvate metabolism_Homo sapiens_hsa006200.14893307
98Linoleic acid metabolism_Homo sapiens_hsa005910.14088285
99Small cell lung cancer_Homo sapiens_hsa052220.13971705
100Caffeine metabolism_Homo sapiens_hsa002320.11597310
101Chemical carcinogenesis_Homo sapiens_hsa052040.10226777
102N-Glycan biosynthesis_Homo sapiens_hsa005100.09308987
103Alcoholism_Homo sapiens_hsa050340.07892709
104Nitrogen metabolism_Homo sapiens_hsa009100.07890639
105Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.07862664
106Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.07074761
107HIF-1 signaling pathway_Homo sapiens_hsa040660.05586558
108MicroRNAs in cancer_Homo sapiens_hsa052060.05582003
109Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.05532640
110Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.05206882
111Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.05191156
112Hippo signaling pathway_Homo sapiens_hsa043900.04586865
113Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.03664421
114Phenylalanine metabolism_Homo sapiens_hsa003600.03260875
115TGF-beta signaling pathway_Homo sapiens_hsa043500.02290223
116NOD-like receptor signaling pathway_Homo sapiens_hsa046210.01842984
117Asthma_Homo sapiens_hsa053100.01788969
118Shigellosis_Homo sapiens_hsa051310.01549551
119Cardiac muscle contraction_Homo sapiens_hsa04260-0.0392529
120NF-kappa B signaling pathway_Homo sapiens_hsa04064-0.0377171
121Bladder cancer_Homo sapiens_hsa05219-0.0352897
122Circadian rhythm_Homo sapiens_hsa04710-0.0346377
123Retinol metabolism_Homo sapiens_hsa00830-0.0240228
124Hepatitis B_Homo sapiens_hsa05161-0.0223879
125Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980-0.0152939
126Transcriptional misregulation in cancer_Homo sapiens_hsa05202-0.0120915
127Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524-0.0039960

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