GOLGA2P11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to pheromone (GO:0019236)5.23120537
2protein K11-linked deubiquitination (GO:0035871)5.12304262
3sperm motility (GO:0030317)5.01156510
4cilium or flagellum-dependent cell motility (GO:0001539)4.78280427
5piRNA metabolic process (GO:0034587)4.76546186
6acrosome reaction (GO:0007340)4.67897646
7tryptophan catabolic process (GO:0006569)4.55564485
8indole-containing compound catabolic process (GO:0042436)4.55564485
9indolalkylamine catabolic process (GO:0046218)4.55564485
10multicellular organism reproduction (GO:0032504)4.54785580
11tachykinin receptor signaling pathway (GO:0007217)4.33570486
12detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)4.18575627
13establishment of protein localization to Golgi (GO:0072600)4.17489927
14male meiosis (GO:0007140)4.10428085
15indolalkylamine metabolic process (GO:0006586)4.07323438
16DNA methylation involved in gamete generation (GO:0043046)3.99453403
17DNA double-strand break processing (GO:0000729)3.95670402
18signal peptide processing (GO:0006465)3.91166354
19fucose catabolic process (GO:0019317)3.88899082
20L-fucose metabolic process (GO:0042354)3.88899082
21L-fucose catabolic process (GO:0042355)3.88899082
22synapsis (GO:0007129)3.87813141
23tryptophan metabolic process (GO:0006568)3.78801939
24kynurenine metabolic process (GO:0070189)3.76667554
25sperm-egg recognition (GO:0035036)3.71193645
26epithelial cilium movement (GO:0003351)3.65359826
27fusion of sperm to egg plasma membrane (GO:0007342)3.64048219
28spermatid development (GO:0007286)3.55648049
29detection of light stimulus involved in sensory perception (GO:0050962)3.54462627
30detection of light stimulus involved in visual perception (GO:0050908)3.54462627
31protein targeting to Golgi (GO:0000042)3.52023798
32regulation of meiosis I (GO:0060631)3.51020138
33epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.50308256
34negative regulation of calcium ion transport into cytosol (GO:0010523)3.50170462
35protein polyglutamylation (GO:0018095)3.50006282
36male meiosis I (GO:0007141)3.47471974
37cellular ketone body metabolic process (GO:0046950)3.46873486
38photoreceptor cell maintenance (GO:0045494)3.46609597
39behavioral response to nicotine (GO:0035095)3.28364282
40centriole replication (GO:0007099)3.24861215
41cellular biogenic amine catabolic process (GO:0042402)3.23302043
42amine catabolic process (GO:0009310)3.23302043
43regulation of hippo signaling (GO:0035330)3.22410951
44cell-cell recognition (GO:0009988)3.21938101
45axoneme assembly (GO:0035082)3.21301181
46protein K48-linked deubiquitination (GO:0071108)3.20238098
47reproduction (GO:0000003)3.20097589
48reflex (GO:0060004)3.18945599
49NAD biosynthetic process (GO:0009435)3.18723981
50behavioral response to ethanol (GO:0048149)3.17661238
51cilium movement (GO:0003341)3.16694560
52reciprocal meiotic recombination (GO:0007131)3.15471915
53reciprocal DNA recombination (GO:0035825)3.15471915
54retrograde transport, vesicle recycling within Golgi (GO:0000301)3.14871617
55retinal cone cell development (GO:0046549)3.12283303
56ketone body metabolic process (GO:1902224)3.09189578
57detection of mechanical stimulus involved in sensory perception (GO:0050974)3.07556955
58phosphatidylethanolamine metabolic process (GO:0046337)3.02941334
59neural tube formation (GO:0001841)3.01652305
60microtubule polymerization or depolymerization (GO:0031109)3.00748189
61adaptation of signaling pathway (GO:0023058)2.99071806
62sulfation (GO:0051923)2.94401340
63auditory receptor cell stereocilium organization (GO:0060088)2.90577743
64negative regulation of mast cell activation (GO:0033004)2.90169302
65chromosome organization involved in meiosis (GO:0070192)2.89995508
66phosphatidylethanolamine biosynthetic process (GO:0006646)2.88294816
67double-strand break repair via homologous recombination (GO:0000724)2.85258377
68DNA integration (GO:0015074)2.85128031
69indole-containing compound metabolic process (GO:0042430)2.82598924
70recombinational repair (GO:0000725)2.82571923
71cilium organization (GO:0044782)2.78660521
72cilium assembly (GO:0042384)2.77814280
73plasma membrane fusion (GO:0045026)2.76797185
74detection of chemical stimulus involved in sensory perception of smell (GO:0050911)2.76734261
75regulation of cilium movement (GO:0003352)2.76303286
76single strand break repair (GO:0000012)2.75585592
77axonemal dynein complex assembly (GO:0070286)2.72515240
78male gamete generation (GO:0048232)2.71704496
79spermatogenesis (GO:0007283)2.71658213
80prenylation (GO:0097354)2.70621010
81protein prenylation (GO:0018342)2.70621010
82microtubule depolymerization (GO:0007019)2.70499369
83cilium morphogenesis (GO:0060271)2.70182384
84benzene-containing compound metabolic process (GO:0042537)2.68891245
85L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.65320597
86single fertilization (GO:0007338)2.62253968
87monoubiquitinated protein deubiquitination (GO:0035520)2.62031822
88dopamine transport (GO:0015872)2.61643273
89binding of sperm to zona pellucida (GO:0007339)2.61641404
90meiotic nuclear division (GO:0007126)2.61026380
91regulation of acrosome reaction (GO:0060046)2.60274588
92rRNA methylation (GO:0031167)2.59634495
93meiosis I (GO:0007127)2.59270553
94protein K63-linked deubiquitination (GO:0070536)2.58423098
95gene silencing by RNA (GO:0031047)2.57790507
96fertilization (GO:0009566)2.53200167
97gamete generation (GO:0007276)2.52313269
98centriole assembly (GO:0098534)2.52048289
99positive regulation of developmental pigmentation (GO:0048087)2.49889345
100cellular response to sterol (GO:0036315)2.49803031

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.37117250
2ZNF274_21170338_ChIP-Seq_K562_Hela3.17543663
3VDR_22108803_ChIP-Seq_LS180_Human2.91794429
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.83188346
5GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.80409708
6IGF1R_20145208_ChIP-Seq_DFB_Human2.75851346
7TAF15_26573619_Chip-Seq_HEK293_Human2.59680835
8CTBP2_25329375_ChIP-Seq_LNCAP_Human2.47584109
9ZFP57_27257070_Chip-Seq_ESCs_Mouse2.41979792
10POU3F2_20337985_ChIP-ChIP_501MEL_Human2.38396857
11FLI1_27457419_Chip-Seq_LIVER_Mouse2.36935421
12CTBP1_25329375_ChIP-Seq_LNCAP_Human2.16952080
13P300_19829295_ChIP-Seq_ESCs_Human2.16413661
14ER_23166858_ChIP-Seq_MCF-7_Human2.14520469
15EZH2_22144423_ChIP-Seq_EOC_Human2.12865369
16FUS_26573619_Chip-Seq_HEK293_Human2.11704617
17AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.00556978
18CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.98534246
19SALL1_21062744_ChIP-ChIP_HESCs_Human1.97813637
20PCGF2_27294783_Chip-Seq_ESCs_Mouse1.93194698
21CBP_20019798_ChIP-Seq_JUKART_Human1.91739617
22IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.91739617
23UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.91661669
24MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.89764634
25STAT3_23295773_ChIP-Seq_U87_Human1.89622023
26SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.81214122
27EWS_26573619_Chip-Seq_HEK293_Human1.79290240
28SMAD4_21799915_ChIP-Seq_A2780_Human1.77751644
29TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.76882490
30POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.76882490
31BCAT_22108803_ChIP-Seq_LS180_Human1.74025554
32AR_21572438_ChIP-Seq_LNCaP_Human1.73402507
33TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.68317600
34TCF4_23295773_ChIP-Seq_U87_Human1.66365163
35AR_25329375_ChIP-Seq_VCAP_Human1.65327097
36PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.59175649
37SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.57838211
38EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.56846807
39NR3C1_21868756_ChIP-Seq_MCF10A_Human1.56814223
40PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.56484481
41KLF5_20875108_ChIP-Seq_MESCs_Mouse1.48634658
42EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.45243706
43FOXA1_21572438_ChIP-Seq_LNCaP_Human1.45188783
44SMAD3_21741376_ChIP-Seq_EPCs_Human1.44606576
45PCGF2_27294783_Chip-Seq_NPCs_Mouse1.44351348
46RUNX2_22187159_ChIP-Seq_PCA_Human1.43459733
47TCF4_22108803_ChIP-Seq_LS180_Human1.43353534
48TOP2B_26459242_ChIP-Seq_MCF-7_Human1.42633974
49PRDM14_20953172_ChIP-Seq_ESCs_Human1.40154352
50SUZ12_27294783_Chip-Seq_NPCs_Mouse1.39517890
51EZH2_27294783_Chip-Seq_NPCs_Mouse1.39517363
52SOX2_19829295_ChIP-Seq_ESCs_Human1.39441578
53NANOG_19829295_ChIP-Seq_ESCs_Human1.39441578
54E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.39145093
55PIAS1_25552417_ChIP-Seq_VCAP_Human1.38066846
56SMAD_19615063_ChIP-ChIP_OVARY_Human1.34930168
57MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.34865469
58SMAD4_21741376_ChIP-Seq_EPCs_Human1.34680910
59HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.33500521
60IRF1_19129219_ChIP-ChIP_H3396_Human1.32706207
61NFE2_27457419_Chip-Seq_LIVER_Mouse1.30612274
62FOXA1_25329375_ChIP-Seq_VCAP_Human1.27190715
63FOXA1_27270436_Chip-Seq_PROSTATE_Human1.27190715
64CDX2_22108803_ChIP-Seq_LS180_Human1.23604586
65FLI1_21867929_ChIP-Seq_TH2_Mouse1.21951895
66BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.21860134
67CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.20444830
68TP53_22573176_ChIP-Seq_HFKS_Human1.20369229
69NANOG_18555785_Chip-Seq_ESCs_Mouse1.17199672
70MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.14904490
71IRF8_22096565_ChIP-ChIP_GC-B_Human1.14540529
72EGR1_23403033_ChIP-Seq_LIVER_Mouse1.14009255
73CRX_20693478_ChIP-Seq_RETINA_Mouse1.13207224
74GATA3_21878914_ChIP-Seq_MCF-7_Human1.11323401
75TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.11273104
76AUTS2_25519132_ChIP-Seq_293T-REX_Human1.08477557
77SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08095148
78TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08036599
79NOTCH1_21737748_ChIP-Seq_TLL_Human1.07673946
80OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07660530
81OCT4_21477851_ChIP-Seq_ESCs_Mouse1.06334318
82TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.04239973
83GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.04096971
84KDM2B_26808549_Chip-Seq_REH_Human1.01367391
85TP53_16413492_ChIP-PET_HCT116_Human1.01179566
86DROSHA_22980978_ChIP-Seq_HELA_Human1.01036276
87FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.00557676
88SOX2_21211035_ChIP-Seq_LN229_Gbm1.00032800
89CDX2_19796622_ChIP-Seq_MESCs_Mouse0.99570960
90ARNT_22903824_ChIP-Seq_MCF-7_Human0.99416861
91EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.98691684
92TBL1_22424771_ChIP-Seq_293T_Human0.98495776
93SMRT_27268052_Chip-Seq_Bcells_Human0.98438804
94SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.98110283
95TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.97941194
96SMAD3_21741376_ChIP-Seq_ESCs_Human0.97662128
97RXR_22108803_ChIP-Seq_LS180_Human0.97183991
98ETV1_20927104_ChIP-Seq_GIST48_Human0.96056941
99PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.95649531
100REST_21632747_ChIP-Seq_MESCs_Mouse0.95254204

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization3.84846151
2MP0000569_abnormal_digit_pigmentation3.60792599
3MP0003195_calcinosis3.11528644
4MP0008877_abnormal_DNA_methylation2.88315707
5MP0001968_abnormal_touch/_nociception2.76932906
6MP0002736_abnormal_nociception_after2.67047955
7MP0005551_abnormal_eye_electrophysiolog2.49501577
8MP0000372_irregular_coat_pigmentation2.46526472
9MP0003646_muscle_fatigue2.42392131
10MP0008057_abnormal_DNA_replication2.40805703
11MP0005075_abnormal_melanosome_morpholog2.22733177
12MP0003698_abnormal_male_reproductive2.17687998
13MP0001501_abnormal_sleep_pattern2.11845610
14MP0001929_abnormal_gametogenesis1.92081925
15MP0003878_abnormal_ear_physiology1.91941455
16MP0005377_hearing/vestibular/ear_phenot1.91941455
17MP0003718_maternal_effect1.89515518
18MP0005253_abnormal_eye_physiology1.81795173
19MP0002138_abnormal_hepatobiliary_system1.79732648
20MP0005174_abnormal_tail_pigmentation1.79493356
21MP0001486_abnormal_startle_reflex1.72029473
22MP0005310_abnormal_salivary_gland1.71598322
23MP0002102_abnormal_ear_morphology1.70188198
24MP0005645_abnormal_hypothalamus_physiol1.69192718
25MP0000015_abnormal_ear_pigmentation1.68011013
26MP0005646_abnormal_pituitary_gland1.65931018
27MP0009046_muscle_twitch1.62423494
28MP0003011_delayed_dark_adaptation1.60181912
29MP0008872_abnormal_physiological_respon1.60038546
30MP0001984_abnormal_olfaction1.59959622
31MP0005670_abnormal_white_adipose1.58057407
32MP0006292_abnormal_olfactory_placode1.45557706
33MP0009745_abnormal_behavioral_response1.44932034
34MP0002735_abnormal_chemical_nociception1.42304639
35MP0001986_abnormal_taste_sensitivity1.41435172
36MP0005167_abnormal_blood-brain_barrier1.40247401
37MP0002210_abnormal_sex_determination1.39883847
38MP0008058_abnormal_DNA_repair1.38483961
39MP0006276_abnormal_autonomic_nervous1.38455329
40MP0004043_abnormal_pH_regulation1.37537802
41MP0004145_abnormal_muscle_electrophysio1.37149623
42MP0003045_fibrosis1.34978481
43MP0001485_abnormal_pinna_reflex1.31008152
44MP0003950_abnormal_plasma_membrane1.30745067
45MP0002095_abnormal_skin_pigmentation1.27774625
46MP0005395_other_phenotype1.27444399
47MP0009697_abnormal_copulation1.26193672
48MP0005408_hypopigmentation1.26148795
49MP0002876_abnormal_thyroid_physiology1.24610971
50MP0002067_abnormal_sensory_capabilities1.23907349
51MP0000383_abnormal_hair_follicle1.23107516
52MP0004742_abnormal_vestibular_system1.22946574
53MP0000427_abnormal_hair_cycle1.22411355
54MP0002272_abnormal_nervous_system1.21846587
55MP0003136_yellow_coat_color1.21411286
56MP0002229_neurodegeneration1.20200411
57MP0008875_abnormal_xenobiotic_pharmacok1.19206507
58MP0000371_diluted_coat_color1.17100742
59MP0002653_abnormal_ependyma_morphology1.17018028
60MP0002168_other_aberrant_phenotype1.15932760
61MP0000653_abnormal_sex_gland1.14658882
62MP0002234_abnormal_pharynx_morphology1.14517245
63MP0005647_abnormal_sex_gland1.13130284
64MP0001529_abnormal_vocalization1.10662645
65MP0001145_abnormal_male_reproductive1.10559917
66MP0000631_abnormal_neuroendocrine_gland1.07743483
67MP0003183_abnormal_peptide_metabolism1.07364888
68MP0002638_abnormal_pupillary_reflex1.06836305
69MP0004147_increased_porphyrin_level1.06598278
70MP0002928_abnormal_bile_duct1.02382602
71MP0006072_abnormal_retinal_apoptosis0.95600881
72MP0002161_abnormal_fertility/fecundity0.95474875
73MP0004142_abnormal_muscle_tone0.94415564
74MP0003252_abnormal_bile_duct0.93169511
75MP0001324_abnormal_eye_pigmentation0.93020816
76MP0003880_abnormal_central_pattern0.91616769
77MP0002572_abnormal_emotion/affect_behav0.91224996
78MP0002938_white_spotting0.91026691
79MP0001970_abnormal_pain_threshold0.90733604
80MP0002733_abnormal_thermal_nociception0.89180603
81MP0005671_abnormal_response_to0.87169110
82MP0005389_reproductive_system_phenotype0.86654730
83MP0001963_abnormal_hearing_physiology0.84317664
84MP0005171_absent_coat_pigmentation0.84281909
85MP0002557_abnormal_social/conspecific_i0.83233333
86MP0008789_abnormal_olfactory_epithelium0.77762587
87MP0003635_abnormal_synaptic_transmissio0.77115747
88MP0005379_endocrine/exocrine_gland_phen0.76893871
89MP0001119_abnormal_female_reproductive0.76649816
90MP0001764_abnormal_homeostasis0.75845049
91MP0000230_abnormal_systemic_arterial0.75056067
92MP0003763_abnormal_thymus_physiology0.75044369
93MP0010386_abnormal_urinary_bladder0.74060870
94MP0002064_seizures0.73655394
95MP0004924_abnormal_behavior0.73419833
96MP0005386_behavior/neurological_phenoty0.73419833
97MP0009764_decreased_sensitivity_to0.73257950
98MP0005195_abnormal_posterior_eye0.72292331
99MP0000026_abnormal_inner_ear0.70807964
100MP0001348_abnormal_lacrimal_gland0.70732302

Predicted human phenotypes

RankGene SetZ-score
1Attenuation of retinal blood vessels (HP:0007843)4.34508871
2Pancreatic cysts (HP:0001737)4.28970456
3Pancreatic fibrosis (HP:0100732)3.66509875
4True hermaphroditism (HP:0010459)3.63834231
5Nephronophthisis (HP:0000090)3.56687774
6Severe visual impairment (HP:0001141)3.47089843
7Molar tooth sign on MRI (HP:0002419)3.39498983
8Abnormality of midbrain morphology (HP:0002418)3.39498983
9Congenital stationary night blindness (HP:0007642)3.28776625
10Chronic hepatic failure (HP:0100626)3.25667253
11Abnormality of the renal medulla (HP:0100957)3.23283605
12Abnormality of macular pigmentation (HP:0008002)3.20466198
13Bony spicule pigmentary retinopathy (HP:0007737)3.13462763
14Decreased central vision (HP:0007663)3.12315085
15Abnormality of the renal cortex (HP:0011035)3.11509580
16Abolished electroretinogram (ERG) (HP:0000550)3.08928714
17Congenital sensorineural hearing impairment (HP:0008527)3.02420486
18Abnormal rod and cone electroretinograms (HP:0008323)3.02068268
19Abnormal biliary tract physiology (HP:0012439)2.98309639
20Bile duct proliferation (HP:0001408)2.98309639
21Increased corneal curvature (HP:0100692)2.79518592
22Keratoconus (HP:0000563)2.79518592
23Gaze-evoked nystagmus (HP:0000640)2.77526987
24Absent/shortened dynein arms (HP:0200106)2.75742619
25Dynein arm defect of respiratory motile cilia (HP:0012255)2.75742619
26Cystic liver disease (HP:0006706)2.66850609
27Hyperventilation (HP:0002883)2.66176270
28Tubulointerstitial nephritis (HP:0001970)2.54609672
29Absent rod-and cone-mediated responses on ERG (HP:0007688)2.53349662
30Pendular nystagmus (HP:0012043)2.53163490
31Cerebellar dysplasia (HP:0007033)2.47028216
32Medial flaring of the eyebrow (HP:0010747)2.41010638
33IgG deficiency (HP:0004315)2.39746641
34Type II lissencephaly (HP:0007260)2.37846791
35Aplasia/Hypoplasia of the tongue (HP:0010295)2.36677453
36Febrile seizures (HP:0002373)2.31978975
37Absent speech (HP:0001344)2.31430077
38Abnormality of B cell number (HP:0010975)2.30091893
39Polydipsia (HP:0001959)2.29821555
40Abnormal drinking behavior (HP:0030082)2.29821555
41Renal cortical cysts (HP:0000803)2.29653726
42Congenital hepatic fibrosis (HP:0002612)2.29314627
43Abnormal ciliary motility (HP:0012262)2.24898910
44Anencephaly (HP:0002323)2.22362570
45Inability to walk (HP:0002540)2.20734911
46Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.20234939
47Aplasia/Hypoplasia of the uvula (HP:0010293)2.15150097
48Retinal dysplasia (HP:0007973)2.15058351
49Progressive cerebellar ataxia (HP:0002073)2.12957539
50Sclerocornea (HP:0000647)2.11651951
51Aplasia/Hypoplasia of the tibia (HP:0005772)2.10011146
52Genetic anticipation (HP:0003743)2.09492496
53Tubular atrophy (HP:0000092)2.09210708
54Central scotoma (HP:0000603)2.08894637
55Thyroiditis (HP:0100646)2.07441279
56Progressive inability to walk (HP:0002505)2.06559082
57Azoospermia (HP:0000027)2.04966973
58Postaxial foot polydactyly (HP:0001830)2.04493158
59Abnormal respiratory motile cilium physiology (HP:0012261)2.03242977
60Stomatitis (HP:0010280)2.03049651
61Abnormal spermatogenesis (HP:0008669)2.02697953
62Decreased electroretinogram (ERG) amplitude (HP:0000654)2.01784193
63B lymphocytopenia (HP:0010976)1.98849453
64Thyroid-stimulating hormone excess (HP:0002925)1.97339400
65Hyperalaninemia (HP:0003348)1.97277265
66Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.97277265
67Abnormality of alanine metabolism (HP:0010916)1.97277265
68Stomach cancer (HP:0012126)1.97191677
69Astigmatism (HP:0000483)1.94862404
70Abnormal respiratory epithelium morphology (HP:0012253)1.94034602
71Abnormal respiratory motile cilium morphology (HP:0005938)1.94034602
72Abnormality of the ileum (HP:0001549)1.93982333
73Clubbing of toes (HP:0100760)1.93269099
74Protruding tongue (HP:0010808)1.92098037
75Macular degeneration (HP:0000608)1.91626108
76Albinism (HP:0001022)1.90911153
77Clumsiness (HP:0002312)1.90611416
78Congenital primary aphakia (HP:0007707)1.90278436
79Abnormality of T cell physiology (HP:0011840)1.88192564
80Gait imbalance (HP:0002141)1.85592097
81Oligodactyly (hands) (HP:0001180)1.85499566
82Polyuria (HP:0000103)1.83458948
83Sloping forehead (HP:0000340)1.81663634
84Photophobia (HP:0000613)1.79492475
85Scotoma (HP:0000575)1.79406186
86Gonadotropin excess (HP:0000837)1.78183946
87Male pseudohermaphroditism (HP:0000037)1.77559966
88Abnormality of the pubic bones (HP:0003172)1.77554050
89Meckel diverticulum (HP:0002245)1.76643139
90Increased neuronal autofluorescent lipopigment (HP:0002074)1.75718366
91Facial diplegia (HP:0001349)1.75451517
92Tubulointerstitial abnormality (HP:0001969)1.74587912
93Widely spaced teeth (HP:0000687)1.74393044
94Hypoplastic ischia (HP:0003175)1.73833594
95Genital tract atresia (HP:0001827)1.69033577
96Dialeptic seizures (HP:0011146)1.68952139
97Submucous cleft hard palate (HP:0000176)1.68461493
98Nephrogenic diabetes insipidus (HP:0009806)1.67758779
99Hypoplasia of the fovea (HP:0007750)1.67053466
100Aplasia/Hypoplasia of the fovea (HP:0008060)1.67053466

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK6.78225473
2NUAK13.17801697
3MAP4K23.09846378
4ACVR1B2.86656278
5PINK12.70785764
6ADRBK22.67364207
7BMPR1B2.60400036
8ZAK2.58354096
9WNK32.57354283
10INSRR2.36670777
11LATS12.30852342
12TAOK32.28384773
13PLK42.24981156
14TXK2.06881583
15MAPK131.87542998
16GRK11.83579148
17MAP3K41.77869269
18STK38L1.61156994
19MUSK1.59718567
20PLK21.37650272
21PIK3CG1.36154829
22EIF2AK31.33955929
23TRIM281.30827932
24CASK1.24586780
25OXSR11.24533606
26PTK2B1.16782555
27NTRK31.14497171
28STK31.02359908
29TEC1.00828719
30TNIK1.00652114
31AKT30.97061277
32STK390.95120045
33ADRBK10.83134129
34SIK20.83110816
35CSNK1G10.80669328
36MARK30.79851607
37CSNK1A1L0.79388796
38MKNK20.79248611
39PNCK0.77507950
40MAP2K70.76114392
41PAK30.74370446
42PRKCE0.73662810
43BCR0.72636578
44STK380.69298737
45CSNK1G30.68836292
46ERBB30.66662013
47CSNK1G20.66208413
48MAPK110.65549580
49IRAK10.65375045
50CDK190.64158985
51TIE10.63661120
52BRD40.63395415
53PRKCQ0.62405372
54TNK20.60615739
55FER0.60342949
56PKN10.60267066
57IKBKB0.60239501
58NEK60.59754343
59TLK10.57680002
60MST40.57614132
61FLT30.57371139
62WNK40.57216922
63KIT0.53827564
64BCKDK0.52934651
65PRKCG0.52680502
66TGFBR10.51873896
67SYK0.50427749
68CAMK1G0.49881504
69MKNK10.48655981
70DYRK20.47726931
71BLK0.46134660
72BRSK20.45455871
73MARK10.43826709
74DAPK20.43591156
75BMPR20.42853614
76PRKAA20.42812247
77OBSCN0.42725969
78SGK20.40318035
79PRKG10.40274381
80CSNK1D0.37574513
81PDK10.37571175
82DDR20.37310094
83CAMK10.36769566
84PBK0.36671479
85CSNK1A10.34535386
86NME10.33747717
87ITK0.33244727
88MAP2K10.32976182
89PRKCI0.32792247
90ATM0.32621468
91CAMK2A0.31823128
92IGF1R0.30529707
93PRKACA0.30332086
94NLK0.30247415
95PRKCZ0.28642608
96CDK30.28500385
97CHEK20.28249586
98PRKCA0.27227221
99CAMKK20.26424421
100PRKACB0.25928222

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.98857920
2Butanoate metabolism_Homo sapiens_hsa006502.66189600
3Phototransduction_Homo sapiens_hsa047442.62723181
4Primary immunodeficiency_Homo sapiens_hsa053402.48789910
5Homologous recombination_Homo sapiens_hsa034402.34160335
6Nitrogen metabolism_Homo sapiens_hsa009102.21976431
7Olfactory transduction_Homo sapiens_hsa047402.21642152
8Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.13565858
9Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.13117773
10Linoleic acid metabolism_Homo sapiens_hsa005912.05861952
11Nicotine addiction_Homo sapiens_hsa050332.05086496
12Selenocompound metabolism_Homo sapiens_hsa004502.01891849
13alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.98798198
14Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.95654058
15Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.93962800
16Fanconi anemia pathway_Homo sapiens_hsa034601.88800294
17ABC transporters_Homo sapiens_hsa020101.84234237
18Taste transduction_Homo sapiens_hsa047421.83379854
19Tryptophan metabolism_Homo sapiens_hsa003801.82954588
20Propanoate metabolism_Homo sapiens_hsa006401.77737618
21Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.75618998
22Basal transcription factors_Homo sapiens_hsa030221.64805217
23Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.63913654
24Intestinal immune network for IgA production_Homo sapiens_hsa046721.61837620
25Primary bile acid biosynthesis_Homo sapiens_hsa001201.60424508
26Ether lipid metabolism_Homo sapiens_hsa005651.60338951
27Caffeine metabolism_Homo sapiens_hsa002321.55588349
28Steroid hormone biosynthesis_Homo sapiens_hsa001401.52450656
29Glycerolipid metabolism_Homo sapiens_hsa005611.39458870
30Morphine addiction_Homo sapiens_hsa050321.35124075
31Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.28830145
32Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.27420915
33Fatty acid biosynthesis_Homo sapiens_hsa000611.21429020
34Retinol metabolism_Homo sapiens_hsa008301.16053232
35Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.14337557
36Graft-versus-host disease_Homo sapiens_hsa053321.10474823
37Dorso-ventral axis formation_Homo sapiens_hsa043201.09057343
38Glycerophospholipid metabolism_Homo sapiens_hsa005641.08926628
39Arachidonic acid metabolism_Homo sapiens_hsa005901.08451113
40Serotonergic synapse_Homo sapiens_hsa047261.08310719
41Chemical carcinogenesis_Homo sapiens_hsa052041.06261019
42Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.06027731
43Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.05706550
44Calcium signaling pathway_Homo sapiens_hsa040201.04478191
45Salivary secretion_Homo sapiens_hsa049701.04200063
46One carbon pool by folate_Homo sapiens_hsa006700.96315567
47Allograft rejection_Homo sapiens_hsa053300.93395169
48Non-homologous end-joining_Homo sapiens_hsa034500.93291907
49Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.93225594
50Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.92969290
51Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.92876876
52RNA polymerase_Homo sapiens_hsa030200.92697934
53beta-Alanine metabolism_Homo sapiens_hsa004100.90408840
54Autoimmune thyroid disease_Homo sapiens_hsa053200.89667347
55Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.87141792
56Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.86366881
57RNA degradation_Homo sapiens_hsa030180.83479978
58Purine metabolism_Homo sapiens_hsa002300.83049955
59Asthma_Homo sapiens_hsa053100.81347798
60Cysteine and methionine metabolism_Homo sapiens_hsa002700.80763613
61Peroxisome_Homo sapiens_hsa041460.79744940
62GABAergic synapse_Homo sapiens_hsa047270.77409950
63Fatty acid degradation_Homo sapiens_hsa000710.76880337
64Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.74141831
65Lysine degradation_Homo sapiens_hsa003100.69691681
66Glutamatergic synapse_Homo sapiens_hsa047240.69114692
67Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.67286026
68Ovarian steroidogenesis_Homo sapiens_hsa049130.67200537
69Histidine metabolism_Homo sapiens_hsa003400.66011567
70Circadian entrainment_Homo sapiens_hsa047130.64000174
71Vascular smooth muscle contraction_Homo sapiens_hsa042700.62302574
72Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.62224499
73Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.61502936
74Fatty acid metabolism_Homo sapiens_hsa012120.59230605
75Type I diabetes mellitus_Homo sapiens_hsa049400.58290807
76RNA transport_Homo sapiens_hsa030130.53915117
77Circadian rhythm_Homo sapiens_hsa047100.52624026
78Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.50209386
79Metabolic pathways_Homo sapiens_hsa011000.45455681
80Maturity onset diabetes of the young_Homo sapiens_hsa049500.44360200
81Fat digestion and absorption_Homo sapiens_hsa049750.43294420
82NF-kappa B signaling pathway_Homo sapiens_hsa040640.43016551
83Jak-STAT signaling pathway_Homo sapiens_hsa046300.41293888
84Long-term depression_Homo sapiens_hsa047300.39786171
85cAMP signaling pathway_Homo sapiens_hsa040240.38643293
86Pentose and glucuronate interconversions_Homo sapiens_hsa000400.38032654
87Base excision repair_Homo sapiens_hsa034100.37972385
88Mismatch repair_Homo sapiens_hsa034300.36922408
89Sphingolipid metabolism_Homo sapiens_hsa006000.34753503
90Pyrimidine metabolism_Homo sapiens_hsa002400.34742367
91Regulation of autophagy_Homo sapiens_hsa041400.33851329
92SNARE interactions in vesicular transport_Homo sapiens_hsa041300.33511783
93Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.32882699
94Protein export_Homo sapiens_hsa030600.31012037
95Hedgehog signaling pathway_Homo sapiens_hsa043400.29900434
96Cholinergic synapse_Homo sapiens_hsa047250.28948327
97Glutathione metabolism_Homo sapiens_hsa004800.28748572
98Oxytocin signaling pathway_Homo sapiens_hsa049210.28477348
99Insulin secretion_Homo sapiens_hsa049110.28009138
100Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.27888748

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