GNAL

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a stimulatory G protein alpha subunit which mediates odorant signaling in the olfactory epithelium. This protein couples dopamine type 1 receptors and adenosine A2A receptors and is widely expressed in the central nervous system. Mutations in this gene have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)5.67391548
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.59406651
3positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.46014321
4regulation of synapse structural plasticity (GO:0051823)5.45463656
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.31086112
6locomotory exploration behavior (GO:0035641)5.28563139
7vocalization behavior (GO:0071625)5.01776972
8prepulse inhibition (GO:0060134)4.85514651
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.84311703
10pyrimidine nucleobase catabolic process (GO:0006208)4.81742777
11synaptic vesicle exocytosis (GO:0016079)4.80944539
12regulation of glutamate receptor signaling pathway (GO:1900449)4.67671491
13postsynaptic membrane organization (GO:0001941)4.66228653
14regulation of synaptic vesicle exocytosis (GO:2000300)4.63935135
15regulation of long-term neuronal synaptic plasticity (GO:0048169)4.61341952
16* sensory perception of smell (GO:0007608)4.55223392
17glutamate secretion (GO:0014047)4.48246120
18synaptic vesicle docking involved in exocytosis (GO:0016081)4.46591049
19membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.45722045
20regulation of neuronal synaptic plasticity (GO:0048168)4.39685379
21protein localization to synapse (GO:0035418)4.26489067
22positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.26186507
23neurotransmitter secretion (GO:0007269)4.22300946
24synaptic transmission, dopaminergic (GO:0001963)4.22221107
25striatum development (GO:0021756)4.21522788
26neuron cell-cell adhesion (GO:0007158)4.19399165
27auditory behavior (GO:0031223)4.17927587
28ionotropic glutamate receptor signaling pathway (GO:0035235)4.16729881
29layer formation in cerebral cortex (GO:0021819)4.14726925
30regulation of synaptic vesicle transport (GO:1902803)4.14405944
31activation of protein kinase A activity (GO:0034199)4.13714109
32neurotransmitter-gated ion channel clustering (GO:0072578)4.12242040
33positive regulation of synaptic transmission, GABAergic (GO:0032230)4.07230794
34exploration behavior (GO:0035640)4.00176562
35behavioral response to cocaine (GO:0048148)3.99158593
36nucleobase catabolic process (GO:0046113)3.98690821
37neuronal action potential propagation (GO:0019227)3.96332232
38gamma-aminobutyric acid transport (GO:0015812)3.91547280
39behavioral response to nicotine (GO:0035095)3.91501629
40neuron-neuron synaptic transmission (GO:0007270)3.88094926
41dendritic spine morphogenesis (GO:0060997)3.87129028
42negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.86846506
43presynaptic membrane assembly (GO:0097105)3.84050266
44response to auditory stimulus (GO:0010996)3.83056205
45regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.82863332
46negative regulation of cytosolic calcium ion concentration (GO:0051481)3.81305903
47positive regulation of neurotransmitter transport (GO:0051590)3.81034762
48positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.79937692
49synaptic transmission, glutamatergic (GO:0035249)3.78207469
50* dopamine receptor signaling pathway (GO:0007212)3.77464430
51positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.77439911
52neurofilament cytoskeleton organization (GO:0060052)3.74767586
53long-term memory (GO:0007616)3.73108735
54neuromuscular process controlling balance (GO:0050885)3.72517608
55regulation of excitatory postsynaptic membrane potential (GO:0060079)3.71602431
56positive regulation of membrane potential (GO:0045838)3.68835511
57establishment of mitochondrion localization (GO:0051654)3.66970830
58regulation of dendritic spine morphogenesis (GO:0061001)3.65717632
59presynaptic membrane organization (GO:0097090)3.65460820
60glutamate receptor signaling pathway (GO:0007215)3.63815947
61transmission of nerve impulse (GO:0019226)3.59865848
62regulation of synaptic transmission, glutamatergic (GO:0051966)3.57308329
63regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.56430025
64* adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.53760108
65regulation of female receptivity (GO:0045924)3.51884057
66regulation of synaptic plasticity (GO:0048167)3.50819932
67cellular potassium ion homeostasis (GO:0030007)3.49802286
68regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.49022027
69membrane depolarization during action potential (GO:0086010)3.47722504
70regulation of postsynaptic membrane potential (GO:0060078)3.46006827
71mitochondrion transport along microtubule (GO:0047497)3.41017818
72establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.41017818
73proline transport (GO:0015824)3.39566615
74neuronal ion channel clustering (GO:0045161)3.39159954
75positive regulation of neurotransmitter secretion (GO:0001956)3.38077261
76mating behavior (GO:0007617)3.36606123
77regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.35454728
78regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.35454728
79G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.34990418
80neuromuscular synaptic transmission (GO:0007274)3.34701421
81neurotransmitter transport (GO:0006836)3.32877807
82cell migration in hindbrain (GO:0021535)3.31557229
83* response to amphetamine (GO:0001975)3.30892264
84neuronal action potential (GO:0019228)3.29517711
85glycine transport (GO:0015816)3.28592338
86regulation of neurotransmitter secretion (GO:0046928)3.26132436
87membrane hyperpolarization (GO:0060081)3.25307165
88mechanosensory behavior (GO:0007638)3.24812166
89regulation of neurotransmitter transport (GO:0051588)3.24782719
90regulation of protein kinase A signaling (GO:0010738)3.24557591
91adenosine receptor signaling pathway (GO:0001973)3.24478967
92cAMP catabolic process (GO:0006198)3.22883098
93startle response (GO:0001964)3.22437686
94long-term synaptic potentiation (GO:0060291)3.21706194
95vesicle transport along microtubule (GO:0047496)3.21384650
96regulation of neurotransmitter levels (GO:0001505)3.20477353
97membrane depolarization (GO:0051899)3.20113318
98regulation of voltage-gated calcium channel activity (GO:1901385)3.19778737
99female mating behavior (GO:0060180)3.18229450
100negative regulation of dendrite development (GO:2000171)3.17961871
101response to histamine (GO:0034776)3.14646747
102behavioral defense response (GO:0002209)3.14628363
103behavioral fear response (GO:0001662)3.14628363
104positive regulation of synapse maturation (GO:0090129)3.14462233
105regulation of synaptic transmission, GABAergic (GO:0032228)3.11544313
106negative regulation of dendrite morphogenesis (GO:0050774)3.11407243
107sodium ion export (GO:0071436)3.11374764
108regulation of neurotransmitter uptake (GO:0051580)3.10422818
109cerebellar Purkinje cell differentiation (GO:0021702)3.10231621
110neuron recognition (GO:0008038)3.10173528
111regulation of vesicle fusion (GO:0031338)3.09360515
112synapse assembly (GO:0007416)3.08963253
113visual learning (GO:0008542)3.07578893
114regulation of glutamate secretion (GO:0014048)3.06981317
115dendrite morphogenesis (GO:0048813)3.06858847
116substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.04274004
117substrate-independent telencephalic tangential migration (GO:0021826)3.04274004
118neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)3.04169370
119atrial cardiac muscle cell action potential (GO:0086014)3.02305681
120G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.93540132
121negative regulation of synaptic transmission, GABAergic (GO:0032229)2.93290166
122regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.91368035
123potassium ion homeostasis (GO:0055075)2.91322325
124axonal fasciculation (GO:0007413)2.90591877
125positive regulation of potassium ion transmembrane transport (GO:1901381)2.87712522
126cerebellar granule cell differentiation (GO:0021707)2.86850678
127synapse organization (GO:0050808)2.86813116
128cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.85968327
129potassium ion import (GO:0010107)2.82569606
130adult walking behavior (GO:0007628)2.82343925
131gamma-aminobutyric acid signaling pathway (GO:0007214)2.81367872
132positive regulation of dendritic spine development (GO:0060999)2.79195660
133innervation (GO:0060384)2.78041577
134synaptic vesicle endocytosis (GO:0048488)2.77956995
135serotonin metabolic process (GO:0042428)2.77662082
136* synaptic transmission (GO:0007268)2.75587398
137cell communication involved in cardiac conduction (GO:0086065)2.72153729
138glycosphingolipid biosynthetic process (GO:0006688)2.71951900
139positive regulation of dendritic spine morphogenesis (GO:0061003)2.70614250
140detection of calcium ion (GO:0005513)2.70475927
141action potential (GO:0001508)2.66278987

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.95426747
2GBX2_23144817_ChIP-Seq_PC3_Human3.27417173
3* RARB_27405468_Chip-Seq_BRAIN_Mouse3.19556243
4* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.02222559
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.93997517
6* JARID2_20064375_ChIP-Seq_MESCs_Mouse2.90031531
7DROSHA_22980978_ChIP-Seq_HELA_Human2.83265008
8REST_21632747_ChIP-Seq_MESCs_Mouse2.78861016
9* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.65927514
10* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.65927514
11* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.58392631
12* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.56882674
13* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.53295504
14* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.51074388
15MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.42064851
16* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.38293898
17* EZH2_27304074_Chip-Seq_ESCs_Mouse2.28989926
18SUZ12_27294783_Chip-Seq_ESCs_Mouse2.28919857
19* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.26080312
20IKZF1_21737484_ChIP-ChIP_HCT116_Human2.26041999
21REST_18959480_ChIP-ChIP_MESCs_Mouse2.25659337
22EZH2_27294783_Chip-Seq_ESCs_Mouse2.22565639
23* RNF2_27304074_Chip-Seq_ESCs_Mouse2.06165781
24EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.05301972
25CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.03370287
26* EED_16625203_ChIP-ChIP_MESCs_Mouse1.99533296
27NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.94106827
28AR_21572438_ChIP-Seq_LNCaP_Human1.80199439
29ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.79703323
30TAF15_26573619_Chip-Seq_HEK293_Human1.74516506
31ERG_21242973_ChIP-ChIP_JURKAT_Human1.71232867
32* SMAD4_21799915_ChIP-Seq_A2780_Human1.52677790
33* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.50837907
34FUS_26573619_Chip-Seq_HEK293_Human1.46252741
35IGF1R_20145208_ChIP-Seq_DFB_Human1.44229842
36CTBP2_25329375_ChIP-Seq_LNCAP_Human1.42378708
37RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.38952986
38* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.38213789
39VDR_22108803_ChIP-Seq_LS180_Human1.37350178
40GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.34706962
41* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.30266140
42* KDM2B_26808549_Chip-Seq_K562_Human1.29340320
43* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.29176435
44TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.28841286
45RING1B_27294783_Chip-Seq_ESCs_Mouse1.28278921
46DNAJC2_21179169_ChIP-ChIP_NT2_Human1.26600802
47GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26215670
48* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.25883839
49* SOX2_21211035_ChIP-Seq_LN229_Gbm1.25172000
50SMAD3_21741376_ChIP-Seq_EPCs_Human1.24746932
51CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.24139099
52P53_22127205_ChIP-Seq_FIBROBLAST_Human1.23503446
53WT1_25993318_ChIP-Seq_PODOCYTE_Human1.23368270
54TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.21452261
55STAT3_23295773_ChIP-Seq_U87_Human1.20876176
56MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.19735024
57ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.19304218
58NR3C1_23031785_ChIP-Seq_PC12_Mouse1.17168169
59* AR_19668381_ChIP-Seq_PC3_Human1.16721518
60* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.16438507
61PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.16377289
62TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.14903376
63* P300_19829295_ChIP-Seq_ESCs_Human1.14473695
64TOP2B_26459242_ChIP-Seq_MCF-7_Human1.12645934
65AHR_22903824_ChIP-Seq_MCF-7_Human1.11981276
66UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.11146859
67* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.11011854
68TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.10574287
69SMAD_19615063_ChIP-ChIP_OVARY_Human1.10275387
70RING1B_27294783_Chip-Seq_NPCs_Mouse1.09954439
71CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.09944745
72BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.08316576
73KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.08189448
74LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07229826
75* FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.06559122
76GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.06087675
77TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.05943600
78* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.04718271
79MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.04460343
80CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.03566345
81ZFP281_18757296_ChIP-ChIP_E14_Mouse1.03495328
82* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.03035404
83WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.02456031
84ARNT_22903824_ChIP-Seq_MCF-7_Human1.02246715
85VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.01957258
86* JUN_21703547_ChIP-Seq_K562_Human1.01383571
87* PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.01250090
88OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.01213437
89CBP_20019798_ChIP-Seq_JUKART_Human1.01109176
90IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.01109176
91AR_25329375_ChIP-Seq_VCAP_Human1.00833796
92FLI1_27457419_Chip-Seq_LIVER_Mouse1.00441500
93BCAT_22108803_ChIP-Seq_LS180_Human1.00437199
94STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.99487109
95* TCF4_23295773_ChIP-Seq_U87_Human0.97333846
96* RNF2_27304074_Chip-Seq_NSC_Mouse0.97315095
97ZNF274_21170338_ChIP-Seq_K562_Hela0.96804545
98NR3C1_21868756_ChIP-Seq_MCF10A_Human0.96649280
99* SMAD3_21741376_ChIP-Seq_ESCs_Human0.95562378
100GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.95532458
101* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.94954368
102AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.94420628
103CTCF_27219007_Chip-Seq_Bcells_Human0.93718092
104* SMAD4_21741376_ChIP-Seq_HESCs_Human0.93597255
105SOX9_26525672_Chip-Seq_HEART_Mouse0.93463332
106SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.93266069
107* RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.93034170
108PIAS1_25552417_ChIP-Seq_VCAP_Human0.92557563
109FLI1_21867929_ChIP-Seq_TH2_Mouse0.92472403
110* RUNX2_22187159_ChIP-Seq_PCA_Human0.92068154
111CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90772394
112CBX2_27304074_Chip-Seq_ESCs_Mouse0.90643239
113* PRDM14_20953172_ChIP-Seq_ESCs_Human0.89971617
114TET1_21490601_ChIP-Seq_MESCs_Mouse0.89721139
115ESR1_20079471_ChIP-ChIP_T-47D_Human0.89503629
116SMAD3_21741376_ChIP-Seq_HESCs_Human0.89346791
117GATA1_26923725_Chip-Seq_HPCs_Mouse0.87285021
118RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.87104353
119TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86636809
120POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.86636809
121* SMAD4_21741376_ChIP-Seq_EPCs_Human0.86597976
122CDX2_19796622_ChIP-Seq_MESCs_Mouse0.86522184

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.11868192
2MP0002822_catalepsy5.99306232
3MP0003880_abnormal_central_pattern4.21914972
4MP0003635_abnormal_synaptic_transmissio4.09744568
5MP0004270_analgesia3.66184138
6* MP0001984_abnormal_olfaction3.61855639
7MP0009745_abnormal_behavioral_response3.44989401
8MP0002063_abnormal_learning/memory/cond3.33535799
9MP0001968_abnormal_touch/_nociception3.21931882
10MP0002064_seizures2.99262068
11MP0009046_muscle_twitch2.98150567
12MP0005423_abnormal_somatic_nervous2.86978983
13MP0002734_abnormal_mechanical_nocicepti2.83272074
14* MP0002572_abnormal_emotion/affect_behav2.68676816
15MP0002272_abnormal_nervous_system2.67290610
16MP0001486_abnormal_startle_reflex2.66413001
17MP0002736_abnormal_nociception_after2.38303449
18MP0002735_abnormal_chemical_nociception2.35652382
19MP0002733_abnormal_thermal_nociception2.20016664
20MP0001970_abnormal_pain_threshold2.19813600
21MP0002909_abnormal_adrenal_gland2.17844545
22MP0001501_abnormal_sleep_pattern2.04054984
23MP0005646_abnormal_pituitary_gland2.01981233
24MP0001529_abnormal_vocalization1.98002745
25MP0002184_abnormal_innervation1.94358656
26MP0004811_abnormal_neuron_physiology1.86425145
27MP0002067_abnormal_sensory_capabilities1.85592260
28MP0005386_behavior/neurological_phenoty1.85341548
29MP0004924_abnormal_behavior1.85341548
30MP0003123_paternal_imprinting1.83511349
31* MP0002557_abnormal_social/conspecific_i1.76478374
32MP0008569_lethality_at_weaning1.75276591
33MP0003121_genomic_imprinting1.71385124
34MP0001440_abnormal_grooming_behavior1.70314699
35MP0008877_abnormal_DNA_methylation1.66193671
36MP0004858_abnormal_nervous_system1.65321084
37MP0003890_abnormal_embryonic-extraembry1.57847754
38MP0006276_abnormal_autonomic_nervous1.54956973
39MP0001188_hyperpigmentation1.51929899
40MP0000778_abnormal_nervous_system1.50867360
41MP0005499_abnormal_olfactory_system1.47903319
42MP0005394_taste/olfaction_phenotype1.47903319
43MP0003329_amyloid_beta_deposits1.47258612
44MP0003879_abnormal_hair_cell1.45939830
45MP0005645_abnormal_hypothalamus_physiol1.44772016
46MP0003646_muscle_fatigue1.43258523
47MP0000955_abnormal_spinal_cord1.42931809
48MP0009780_abnormal_chondrocyte_physiolo1.41716143
49MP0002882_abnormal_neuron_morphology1.40003935
50MP0003633_abnormal_nervous_system1.33128350
51* MP0002066_abnormal_motor_capabilities/c1.32491958
52MP0000579_abnormal_nail_morphology1.29319757
53MP0001905_abnormal_dopamine_level1.25225463
54MP0002102_abnormal_ear_morphology1.24793321
55MP0004885_abnormal_endolymph1.23610166
56MP0005409_darkened_coat_color1.23221808
57MP0004133_heterotaxia1.17088055
58MP0008874_decreased_physiological_sensi1.15061129
59MP0005187_abnormal_penis_morphology1.13261409
60MP0001986_abnormal_taste_sensitivity1.11053946
61MP0008872_abnormal_physiological_respon1.10636201
62MP0004130_abnormal_muscle_cell1.07184789
63MP0003631_nervous_system_phenotype1.05647957
64MP0002152_abnormal_brain_morphology1.05370217
65MP0004142_abnormal_muscle_tone1.05157820
66MP0003075_altered_response_to1.04632696
67MP0002876_abnormal_thyroid_physiology1.03649147
68MP0001177_atelectasis0.96693018
69MP0001502_abnormal_circadian_rhythm0.95529769
70MP0000013_abnormal_adipose_tissue0.94284592
71MP0002229_neurodegeneration0.93880745
72MP0000569_abnormal_digit_pigmentation0.92656303
73MP0003119_abnormal_digestive_system0.90865020
74MP0004085_abnormal_heartbeat0.88416196
75MP0003787_abnormal_imprinting0.88009294
76MP0003136_yellow_coat_color0.85069822
77* MP0002069_abnormal_eating/drinking_beha0.84973472
78MP0010234_abnormal_vibrissa_follicle0.84840252
79MP0003634_abnormal_glial_cell0.83169228
80MP0001485_abnormal_pinna_reflex0.82706663
81MP0002837_dystrophic_cardiac_calcinosis0.80827849
82MP0005535_abnormal_body_temperature0.80567205
83MP0002752_abnormal_somatic_nervous0.79628644
84MP0000566_synostosis0.79626171
85MP0005167_abnormal_blood-brain_barrier0.78572498
86MP0006292_abnormal_olfactory_placode0.78050063
87MP0008789_abnormal_olfactory_epithelium0.77734829
88MP0004742_abnormal_vestibular_system0.74657237
89MP0003283_abnormal_digestive_organ0.74263315
90MP0004043_abnormal_pH_regulation0.73781088
91MP0003690_abnormal_glial_cell0.73076111
92MP0000631_abnormal_neuroendocrine_gland0.72329149
93MP0000920_abnormal_myelination0.72265150
94MP0005253_abnormal_eye_physiology0.71283189
95MP0008961_abnormal_basal_metabolism0.70528191
96MP0000751_myopathy0.69520469
97MP0005551_abnormal_eye_electrophysiolog0.68745127
98MP0003122_maternal_imprinting0.67846719
99MP0006072_abnormal_retinal_apoptosis0.65419135
100MP0002090_abnormal_vision0.64422198
101MP0003938_abnormal_ear_development0.64045844
102MP0001963_abnormal_hearing_physiology0.62272200
103MP0000604_amyloidosis0.61260735
104MP0000026_abnormal_inner_ear0.60677497
105MP0010386_abnormal_urinary_bladder0.60589851
106MP0005377_hearing/vestibular/ear_phenot0.60341052
107MP0003878_abnormal_ear_physiology0.60341052
108MP0003137_abnormal_impulse_conducting0.60081385
109MP0003632_abnormal_nervous_system0.59770502
110MP0001664_abnormal_digestion0.56737772
111MP0004145_abnormal_muscle_electrophysio0.54845178
112MP0002638_abnormal_pupillary_reflex0.52704244
113MP0005623_abnormal_meninges_morphology0.49307458
114MP0001299_abnormal_eye_distance/0.48442229
115* MP0003956_abnormal_body_size0.47857640
116MP0001943_abnormal_respiration0.47844182
117* MP0010769_abnormal_survival0.46100564
118MP0003861_abnormal_nervous_system0.45913522
119* MP0010770_preweaning_lethality0.45314095
120* MP0002082_postnatal_lethality0.45314095
121MP0004215_abnormal_myocardial_fiber0.43667961
122MP0002653_abnormal_ependyma_morphology0.43555929
123MP0005166_decreased_susceptibility_to0.42765525
124* MP0010768_mortality/aging0.42741597

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)8.34164339
2Focal motor seizures (HP:0011153)7.17988721
3Focal seizures (HP:0007359)5.84195307
4Visual hallucinations (HP:0002367)4.72271959
5Febrile seizures (HP:0002373)4.34168062
6Atonic seizures (HP:0010819)4.22385270
7Action tremor (HP:0002345)4.16965708
8Epileptic encephalopathy (HP:0200134)4.09026476
9Ankle clonus (HP:0011448)3.97024063
10Absence seizures (HP:0002121)3.90841635
11Generalized tonic-clonic seizures (HP:0002069)3.73533562
12Poor eye contact (HP:0000817)3.61888945
13Progressive cerebellar ataxia (HP:0002073)3.59645391
14Dialeptic seizures (HP:0011146)3.53117540
15* Limb dystonia (HP:0002451)3.50038607
16Depression (HP:0000716)3.49771289
17Broad-based gait (HP:0002136)3.43979623
18Anxiety (HP:0000739)3.43263930
19Polyphagia (HP:0002591)3.42340144
20Supranuclear gaze palsy (HP:0000605)3.35406610
21Papilledema (HP:0001085)3.29218033
22Abnormal social behavior (HP:0012433)3.27958327
23Impaired social interactions (HP:0000735)3.27958327
24Annular pancreas (HP:0001734)3.25407584
25Impaired vibration sensation in the lower limbs (HP:0002166)3.21716341
26Mutism (HP:0002300)3.18855159
27Gaze-evoked nystagmus (HP:0000640)3.12731666
28Urinary bladder sphincter dysfunction (HP:0002839)3.12298944
29* Torticollis (HP:0000473)3.07874662
30Truncal ataxia (HP:0002078)2.94498311
31Dysdiadochokinesis (HP:0002075)2.94203571
32Postural instability (HP:0002172)2.89543355
33Urinary urgency (HP:0000012)2.87469205
34Progressive inability to walk (HP:0002505)2.82106160
35Abnormal eating behavior (HP:0100738)2.81193878
36Resting tremor (HP:0002322)2.80203116
37Dysmetria (HP:0001310)2.78444486
38Stereotypic behavior (HP:0000733)2.77371113
39Insidious onset (HP:0003587)2.71278916
40Termporal pattern (HP:0011008)2.71278916
41* Focal dystonia (HP:0004373)2.70506619
42Scanning speech (HP:0002168)2.64426540
43Akinesia (HP:0002304)2.63716566
44Spastic gait (HP:0002064)2.58355703
45* Craniofacial dystonia (HP:0012179)2.56206003
46Abnormal respiratory motile cilium physiology (HP:0012261)2.56120411
47Retinal dysplasia (HP:0007973)2.55812724
48Prolonged QT interval (HP:0001657)2.55448773
49Amblyopia (HP:0000646)2.55020796
50Abnormal ciliary motility (HP:0012262)2.53339824
51Hyperventilation (HP:0002883)2.52429082
52Megalencephaly (HP:0001355)2.49647747
53Ventricular fibrillation (HP:0001663)2.49599389
54Impaired smooth pursuit (HP:0007772)2.46269129
55Genetic anticipation (HP:0003743)2.44870994
56Pointed chin (HP:0000307)2.44312438
57Abnormal EKG (HP:0003115)2.43711544
58Abnormality of the labia minora (HP:0012880)2.41075116
59Bradykinesia (HP:0002067)2.41061222
60Intention tremor (HP:0002080)2.40770434
61Ankyloglossia (HP:0010296)2.35669121
62Abnormality of the lower motor neuron (HP:0002366)2.23680641
63Dysmetric saccades (HP:0000641)2.22516038
64Pheochromocytoma (HP:0002666)2.22348101
65Sleep apnea (HP:0010535)2.19684168
66Lower limb muscle weakness (HP:0007340)2.19425221
67Excessive salivation (HP:0003781)2.19004370
68Drooling (HP:0002307)2.19004370
69Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.18860814
70Impaired vibratory sensation (HP:0002495)2.18073577
71Hemiplegia (HP:0002301)2.17605377
72Morphological abnormality of the pyramidal tract (HP:0002062)2.17346820
73Lower limb amyotrophy (HP:0007210)2.12103464
74Clonus (HP:0002169)2.11817443
75Hemiparesis (HP:0001269)2.11094213
76Impaired pain sensation (HP:0007328)2.10538107
77Abnormality of pain sensation (HP:0010832)2.10538107
78Abnormality of ocular smooth pursuit (HP:0000617)2.09998275
79Diplopia (HP:0000651)2.08939998
80Abnormality of binocular vision (HP:0011514)2.08939998
81Gait imbalance (HP:0002141)2.08861911
82Abnormality of the corticospinal tract (HP:0002492)2.05585283
83Molar tooth sign on MRI (HP:0002419)2.04341808
84Abnormality of midbrain morphology (HP:0002418)2.04341808
85Epileptiform EEG discharges (HP:0011182)2.03715895
86Status epilepticus (HP:0002133)2.03133008
87EEG with generalized epileptiform discharges (HP:0011198)2.02863749
88Inability to walk (HP:0002540)2.01921336
89Insomnia (HP:0100785)2.01474437
90Neuroendocrine neoplasm (HP:0100634)2.00900438
91Nephronophthisis (HP:0000090)2.00291380
92Absent speech (HP:0001344)1.99434896
93Incomplete penetrance (HP:0003829)1.98391784
94Agitation (HP:0000713)1.97217262
95Rhinitis (HP:0012384)1.96984600
96Hypsarrhythmia (HP:0002521)1.96415737
97Neuronal loss in central nervous system (HP:0002529)1.96279310
98Lower limb asymmetry (HP:0100559)1.93428043
99Fetal akinesia sequence (HP:0001989)1.93368111
100Pancreatic fibrosis (HP:0100732)1.92149575
101Neurofibrillary tangles (HP:0002185)1.91973623
102Lissencephaly (HP:0001339)1.91494154
103Inappropriate behavior (HP:0000719)1.87892368
104Specific learning disability (HP:0001328)1.86466946
105Cerebral inclusion bodies (HP:0100314)1.84724286
106Bundle branch block (HP:0011710)1.84127881
107Apathy (HP:0000741)1.83294082
108Spastic tetraplegia (HP:0002510)1.82918538
109Neoplasm of the peripheral nervous system (HP:0100007)1.82840966
110Abnormal respiratory epithelium morphology (HP:0012253)1.82663805
111Abnormal respiratory motile cilium morphology (HP:0005938)1.82663805
112Restlessness (HP:0000711)1.82162873
113Amyotrophic lateral sclerosis (HP:0007354)1.80320820
114Obstructive sleep apnea (HP:0002870)1.80065320
115Protruding tongue (HP:0010808)1.78922788
116Pachygyria (HP:0001302)1.78609566
117Hepatoblastoma (HP:0002884)1.75685011
118Poor suck (HP:0002033)1.74274787
119Optic nerve hypoplasia (HP:0000609)1.70344461
120Pancreatic cysts (HP:0001737)1.69290284
121Generalized myoclonic seizures (HP:0002123)1.66379517
122Spastic tetraparesis (HP:0001285)1.65550340
123Myotonia (HP:0002486)1.65430658
124Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.65019826
125Degeneration of the lateral corticospinal tracts (HP:0002314)1.65019826
126Aqueductal stenosis (HP:0002410)1.64042541
127Labial hypoplasia (HP:0000066)1.63740916
128Congenital stationary night blindness (HP:0007642)1.63377242
129Abnormal pancreas size (HP:0012094)1.62748670
130Anosmia (HP:0000458)1.62436999
131Abnormality of salivation (HP:0100755)1.57771691
132Syncope (HP:0001279)1.57426642
133Paraplegia (HP:0010550)1.56367174
134Failure to thrive in infancy (HP:0001531)1.56047835
135Absent/shortened dynein arms (HP:0200106)1.55558916
136Dynein arm defect of respiratory motile cilia (HP:0012255)1.55558916
137Abnormality of the renal medulla (HP:0100957)1.55445115
138Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.54766033

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA45.37408511
2NTRK34.17137053
3MAP3K93.80738977
4MARK13.04237199
5DAPK22.78233190
6MINK12.65414580
7MAP3K42.52257561
8KSR22.45785912
9CAMKK12.21328149
10RIPK42.14628490
11ARAF2.11847336
12MAP2K72.11658349
13PRKD32.06867413
14NTRK22.05508579
15NTRK12.05383888
16DYRK21.96857345
17FRK1.96612447
18PAK61.87109131
19CAMKK21.68887911
20TNIK1.64125056
21CDK51.59482599
22MAP2K41.55032035
23WNK31.54121543
24KSR11.53953860
25MAP3K21.53568434
26DAPK11.52064663
27PHKG11.50132606
28PHKG21.50132606
29MAP3K121.45485305
30TAOK11.44428019
31FES1.42259565
32SIK21.41206396
33STK381.31486927
34PRPF4B1.31202666
35OBSCN1.30474442
36MAPK131.26511256
37MAP3K131.23167878
38GRK51.18657623
39TYRO31.18085559
40PRKCG1.14700036
41SGK4941.02885917
42SGK2231.02885917
43RAF11.00759437
44BMPR1B0.99276925
45WNK40.97151813
46PINK10.95754848
47CASK0.94172462
48CAMK2B0.93609127
49SGK20.92321304
50CAMK1D0.91246843
51RET0.89773263
52PLK20.88343558
53STK110.86844462
54CSNK1G10.86830840
55LMTK20.86130657
56PRKCH0.86045315
57MKNK20.85804040
58CAMK2A0.85456257
59PKN10.85444872
60RIPK10.84234631
61UHMK10.83999598
62CDK140.83467666
63CDK180.83201932
64FGFR20.82695741
65SGK30.82511092
66CDK150.81024132
67CAMK10.79452885
68MARK20.79108838
69PAK30.78841438
70CSNK1G20.78120964
71BMPR20.76735674
72PNCK0.76483137
73CSNK1A1L0.76474044
74ERBB30.75990333
75ACVR1B0.75489171
76ADRBK20.75253453
77TNK20.74018842
78ALK0.71823078
79CDK11A0.70615170
80STK390.70512016
81PDK10.65586678
82PDPK10.65485288
83CDK190.63916385
84RPS6KA20.63744676
85SGK10.63717243
86MAPK120.63033711
87NEK10.62526254
88CAMK2G0.62225787
89MAP3K10.61752130
90LATS20.61191056
91CAMK2D0.61037321
92CSNK1E0.60274534
93TRIM280.58917764
94PRKCZ0.57688506
95DYRK1A0.54383180
96GRK10.53470760
97FYN0.52795887
98STK38L0.50979312
99BRAF0.49728410
100WNK10.49396442
101PRKG10.48629237
102ZAK0.48519948
103MAP2K10.48441062
104PTK2B0.47556329
105RPS6KA30.47126894
106MAPK100.44721123
107CSNK1D0.43995410
108CAMK40.43257137
109AKT30.43135171
110PRKAA10.41929702
111PRKCE0.41520435
112MAP3K110.39961594
113CDC42BPA0.39215634
114ADRBK10.39115719
115RPS6KB10.37830774
116BCR0.37422178
117SCYL20.37353619
118TAF10.36545614
119DAPK30.36045958
120CAMK1G0.34148105
121PRKACB0.33695570
122PRKCB0.33341973
123NEK60.32495415
124PRKCI0.32495321
125INSRR0.31982215
126PRKDC0.31495423
127GSK3B0.31463926
128BRSK10.31257486
129PRKACA0.27921915
130PRKACG0.27313802
131CSNK1G30.27302640
132OXSR10.25782038
133PRKCA0.25744522
134MUSK0.25415800
135MAPK80.24913780

Predicted pathways (KEGG)

RankGene SetZ-score
1* Olfactory transduction_Homo sapiens_hsa047404.60198872
2Synaptic vesicle cycle_Homo sapiens_hsa047213.02475414
3Nicotine addiction_Homo sapiens_hsa050332.96955910
4Morphine addiction_Homo sapiens_hsa050322.76699552
5Circadian entrainment_Homo sapiens_hsa047132.74354650
6GABAergic synapse_Homo sapiens_hsa047272.72667357
7Glutamatergic synapse_Homo sapiens_hsa047242.49481625
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.46502605
9Long-term potentiation_Homo sapiens_hsa047202.45853960
10Amphetamine addiction_Homo sapiens_hsa050312.44667041
11* Dopaminergic synapse_Homo sapiens_hsa047282.26777097
12Cholinergic synapse_Homo sapiens_hsa047252.14054984
13Salivary secretion_Homo sapiens_hsa049702.09341511
14Cocaine addiction_Homo sapiens_hsa050302.05972474
15Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.98153923
16Insulin secretion_Homo sapiens_hsa049111.93753175
17Aldosterone synthesis and secretion_Homo sapiens_hsa049251.87935000
18Gastric acid secretion_Homo sapiens_hsa049711.85783903
19Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.77777376
20Renin secretion_Homo sapiens_hsa049241.74013251
21Taste transduction_Homo sapiens_hsa047421.72437467
22Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.68451011
23Oxytocin signaling pathway_Homo sapiens_hsa049211.60503479
24Serotonergic synapse_Homo sapiens_hsa047261.57081498
25* Calcium signaling pathway_Homo sapiens_hsa040201.49301671
26Gap junction_Homo sapiens_hsa045401.48016176
27GnRH signaling pathway_Homo sapiens_hsa049121.47428392
28cAMP signaling pathway_Homo sapiens_hsa040241.41736773
29Long-term depression_Homo sapiens_hsa047301.41714170
30Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.41416593
31Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.27304796
32Phototransduction_Homo sapiens_hsa047441.16793184
33Estrogen signaling pathway_Homo sapiens_hsa049151.15978126
34Phosphatidylinositol signaling system_Homo sapiens_hsa040701.12989602
35Glioma_Homo sapiens_hsa052141.12861972
36Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.10578672
37Collecting duct acid secretion_Homo sapiens_hsa049661.09686275
38cGMP-PKG signaling pathway_Homo sapiens_hsa040221.06781640
39Alzheimers disease_Homo sapiens_hsa050101.03915857
40Type II diabetes mellitus_Homo sapiens_hsa049301.02602166
41Oxidative phosphorylation_Homo sapiens_hsa001901.01467031
42Melanogenesis_Homo sapiens_hsa049161.00573059
43Vitamin B6 metabolism_Homo sapiens_hsa007500.97971057
44Nitrogen metabolism_Homo sapiens_hsa009100.95953981
45Vascular smooth muscle contraction_Homo sapiens_hsa042700.94111147
46Axon guidance_Homo sapiens_hsa043600.91698333
47Oocyte meiosis_Homo sapiens_hsa041140.91445651
48ErbB signaling pathway_Homo sapiens_hsa040120.90722485
49Butanoate metabolism_Homo sapiens_hsa006500.89487825
50Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.89234688
51Parkinsons disease_Homo sapiens_hsa050120.89050937
52Phospholipase D signaling pathway_Homo sapiens_hsa040720.85871117
53Dorso-ventral axis formation_Homo sapiens_hsa043200.85733013
54Thyroid hormone synthesis_Homo sapiens_hsa049180.85561986
55Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.84937065
56Alcoholism_Homo sapiens_hsa050340.83903041
57Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.83381373
58Vibrio cholerae infection_Homo sapiens_hsa051100.80748924
59Cardiac muscle contraction_Homo sapiens_hsa042600.80042586
60Pancreatic secretion_Homo sapiens_hsa049720.77082724
61Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.76022488
62Neurotrophin signaling pathway_Homo sapiens_hsa047220.75974988
63Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.75648887
64Hippo signaling pathway_Homo sapiens_hsa043900.73031668
65Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.71427292
66Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.68243456
67Rap1 signaling pathway_Homo sapiens_hsa040150.67254147
68Ether lipid metabolism_Homo sapiens_hsa005650.67096317
69Dilated cardiomyopathy_Homo sapiens_hsa054140.66460134
70Huntingtons disease_Homo sapiens_hsa050160.66161619
71Non-small cell lung cancer_Homo sapiens_hsa052230.65603915
72Hedgehog signaling pathway_Homo sapiens_hsa043400.65227405
73MAPK signaling pathway_Homo sapiens_hsa040100.63912917
74beta-Alanine metabolism_Homo sapiens_hsa004100.63796657
75Choline metabolism in cancer_Homo sapiens_hsa052310.61847252
76Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.61822302
77VEGF signaling pathway_Homo sapiens_hsa043700.61006772
78Endometrial cancer_Homo sapiens_hsa052130.60511351
79Bile secretion_Homo sapiens_hsa049760.59810223
80Ras signaling pathway_Homo sapiens_hsa040140.57911608
81Carbohydrate digestion and absorption_Homo sapiens_hsa049730.57428755
82Thyroid hormone signaling pathway_Homo sapiens_hsa049190.56231893
83Sphingolipid signaling pathway_Homo sapiens_hsa040710.54510262
84Type I diabetes mellitus_Homo sapiens_hsa049400.54379740
85Basal cell carcinoma_Homo sapiens_hsa052170.54156459
86Tight junction_Homo sapiens_hsa045300.54023069
87Longevity regulating pathway - mammal_Homo sapiens_hsa042110.53691665
88Chemokine signaling pathway_Homo sapiens_hsa040620.53147397
89mTOR signaling pathway_Homo sapiens_hsa041500.53115724
90Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.52099106
91Glucagon signaling pathway_Homo sapiens_hsa049220.50650834
92Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.50417319
93Linoleic acid metabolism_Homo sapiens_hsa005910.50387430
94Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.50105139
95Regulation of autophagy_Homo sapiens_hsa041400.49771980
96Insulin signaling pathway_Homo sapiens_hsa049100.48676035
97Ovarian steroidogenesis_Homo sapiens_hsa049130.48365755
98Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.48269726
99Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.48071139
100Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.47815887
101Fatty acid biosynthesis_Homo sapiens_hsa000610.47161778
102Histidine metabolism_Homo sapiens_hsa003400.46669253
103alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.46644599
104Endocytosis_Homo sapiens_hsa041440.46630118
105Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.42972161
106Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.42946243
107Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.41973362
108SNARE interactions in vesicular transport_Homo sapiens_hsa041300.39025131
109Prion diseases_Homo sapiens_hsa050200.38915904
110Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.38457529
111Inositol phosphate metabolism_Homo sapiens_hsa005620.36666151
112Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.35538463
113Propanoate metabolism_Homo sapiens_hsa006400.33787707
114Arginine biosynthesis_Homo sapiens_hsa002200.33748405
115Renal cell carcinoma_Homo sapiens_hsa052110.32112323
116Platelet activation_Homo sapiens_hsa046110.31348321
117Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.29474047
118Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.28483105
119AMPK signaling pathway_Homo sapiens_hsa041520.27649812
120Circadian rhythm_Homo sapiens_hsa047100.27320496
121Glycerophospholipid metabolism_Homo sapiens_hsa005640.27289085
122Colorectal cancer_Homo sapiens_hsa052100.26717039
123Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.24154050
124Prolactin signaling pathway_Homo sapiens_hsa049170.23247569
125Wnt signaling pathway_Homo sapiens_hsa043100.23025581
126African trypanosomiasis_Homo sapiens_hsa051430.22119748

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