GLT8D2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle docking involved in exocytosis (GO:0016081)7.90299555
2peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)6.04281958
3regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)5.73723860
4protein heterotrimerization (GO:0070208)5.63518179
5metanephric mesenchyme development (GO:0072075)5.44779993
6kidney mesenchyme development (GO:0072074)5.44666848
7cell migration involved in heart development (GO:0060973)5.32445220
8vocalization behavior (GO:0071625)5.19330054
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.11892861
10presynaptic membrane assembly (GO:0097105)5.11485674
11keratan sulfate catabolic process (GO:0042340)4.93826741
12regulation of glutamate receptor signaling pathway (GO:1900449)4.76571251
13dermatan sulfate biosynthetic process (GO:0030208)4.71104081
14postsynaptic membrane organization (GO:0001941)4.60564393
15presynaptic membrane organization (GO:0097090)4.59178569
16mesenchymal-epithelial cell signaling (GO:0060638)4.58670362
17positive regulation of neurotransmitter secretion (GO:0001956)4.51542350
18glutamate secretion (GO:0014047)4.51219141
19dermatan sulfate metabolic process (GO:0030205)4.49783157
20positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.47053829
21protein localization to synapse (GO:0035418)4.36175016
22regulation of synaptic vesicle exocytosis (GO:2000300)4.22680714
23regulation of branching involved in salivary gland morphogenesis (GO:0060693)4.22566201
24synaptic vesicle exocytosis (GO:0016079)4.20690005
25glomerular basement membrane development (GO:0032836)4.19527593
26neuron cell-cell adhesion (GO:0007158)4.18019281
27regulation of type B pancreatic cell apoptotic process (GO:2000674)4.15324177
28long-term synaptic potentiation (GO:0060291)4.07141980
29neurotransmitter-gated ion channel clustering (GO:0072578)4.05883941
30gamma-aminobutyric acid signaling pathway (GO:0007214)3.99192140
31ionotropic glutamate receptor signaling pathway (GO:0035235)3.97250572
32skin morphogenesis (GO:0043589)3.96812437
33bone trabecula formation (GO:0060346)3.87498233
34chondrocyte proliferation (GO:0035988)3.87207048
35type B pancreatic cell proliferation (GO:0044342)3.84074244
36regulation of short-term neuronal synaptic plasticity (GO:0048172)3.82533695
37synaptic transmission, glutamatergic (GO:0035249)3.81286597
38glutamate receptor signaling pathway (GO:0007215)3.79661085
39negative regulation of synaptic transmission, GABAergic (GO:0032229)3.79200283
40regulation of synaptic vesicle transport (GO:1902803)3.77645520
41smooth muscle tissue development (GO:0048745)3.76021262
42positive regulation of synapse maturation (GO:0090129)3.72665182
43regulation of excitatory postsynaptic membrane potential (GO:0060079)3.66686215
44neuron-neuron synaptic transmission (GO:0007270)3.63870942
45extracellular fibril organization (GO:0043206)3.63733670
46endodermal cell differentiation (GO:0035987)3.63581640
47collagen metabolic process (GO:0032963)3.59384607
48cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.59062983
49regulation of pigment cell differentiation (GO:0050932)3.58998512
50collagen catabolic process (GO:0030574)3.56688928
51regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)3.54525279
52chondroitin sulfate catabolic process (GO:0030207)3.53794127
53extracellular matrix assembly (GO:0085029)3.47359187
54wound healing, spreading of epidermal cells (GO:0035313)3.47108776
55cellular response to vitamin (GO:0071295)3.46098659
56regulation of postsynaptic membrane potential (GO:0060078)3.43985346
57positive regulation of cardiac muscle cell differentiation (GO:2000727)3.43901442
58neuronal action potential propagation (GO:0019227)3.40094538
59tooth mineralization (GO:0034505)3.39053919
60positive regulation of neurotransmitter transport (GO:0051590)3.37396083
61middle ear morphogenesis (GO:0042474)3.36623050
62endocardial cushion development (GO:0003197)3.35251282
63locomotory exploration behavior (GO:0035641)3.32175111
64cellular response to vitamin D (GO:0071305)3.31844399
65sequestering of extracellular ligand from receptor (GO:0035581)3.31215304
66regulation of long-term neuronal synaptic plasticity (GO:0048169)3.30303291
67multicellular organismal macromolecule metabolic process (GO:0044259)3.30140008
68mesenchymal cell differentiation involved in kidney development (GO:0072161)3.29890158
69mesenchymal cell differentiation involved in renal system development (GO:2001012)3.29890158
70negative regulation of hormone biosynthetic process (GO:0032353)3.29418551
71exploration behavior (GO:0035640)3.28637645
72fibril organization (GO:0097435)3.28136475
73positive regulation of fatty acid oxidation (GO:0046321)3.27715889
74pericardium development (GO:0060039)3.26043591
75embryonic forelimb morphogenesis (GO:0035115)3.24671263
76head development (GO:0060322)3.24469493
77multicellular organismal catabolic process (GO:0044243)3.24155123
78embryonic cranial skeleton morphogenesis (GO:0048701)3.17951130
79regulation of glutamate secretion (GO:0014048)3.17824320
80startle response (GO:0001964)3.17507177
81regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.16792088
82positive regulation of synapse assembly (GO:0051965)3.13819321
83multicellular organismal metabolic process (GO:0044236)3.12935130
84regulation of synaptic plasticity (GO:0048167)3.12473642
85negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037)3.12053749
86collagen fibril organization (GO:0030199)3.10243636
87regulation of synapse maturation (GO:0090128)3.09371040
88regulation of neurotransmitter secretion (GO:0046928)3.08707405
89negative regulation of axon extension involved in axon guidance (GO:0048843)3.08662955
90regulation of Rac GTPase activity (GO:0032314)3.08649412
91organ induction (GO:0001759)3.07904454
92positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-3.07419761
93regulation of organ formation (GO:0003156)3.04776727
94positive regulation of gastrulation (GO:2000543)3.04685739
95trabecula formation (GO:0060343)3.04215017
96mesenchyme morphogenesis (GO:0072132)3.04114256
97protein localization to cell surface (GO:0034394)3.03955450
98planar cell polarity pathway involved in neural tube closure (GO:0090179)3.02935711
99negative regulation of BMP signaling pathway (GO:0030514)3.02086907
100regulation of phospholipase A2 activity (GO:0032429)3.00890683
101blood vessel maturation (GO:0001955)3.00014181
102neuron recognition (GO:0008038)2.98792364
103cerebellar granule cell differentiation (GO:0021707)2.97688518
104embryonic skeletal joint morphogenesis (GO:0060272)2.97349950
105axonal fasciculation (GO:0007413)2.96323966
106regulation of neuronal synaptic plasticity (GO:0048168)2.96310649
107negative regulation of embryonic development (GO:0045992)2.96170196
108cell differentiation involved in metanephros development (GO:0072202)2.95444511
109regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.95257505
110G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.94885611
111adhesion of symbiont to host cell (GO:0044650)2.94742225
112virion attachment to host cell (GO:0019062)2.94742225
113regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.94307168
114serotonin metabolic process (GO:0042428)2.94126226
115extracellular matrix disassembly (GO:0022617)2.93525946
116positive regulation of synaptic transmission (GO:0050806)2.93154668
117regulation of cardioblast proliferation (GO:0003264)2.93027774
118regulation of secondary heart field cardioblast proliferation (GO:0003266)2.93027774
119forelimb morphogenesis (GO:0035136)2.92594653
120positive regulation of membrane potential (GO:0045838)2.88985175
121response to histamine (GO:0034776)2.88934007
122regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.88373384
123positive regulation of fibroblast migration (GO:0010763)2.87578589
124innervation (GO:0060384)2.86594131
125regulation of synapse assembly (GO:0051963)2.84105447
126outer ear morphogenesis (GO:0042473)2.83093337
127urinary tract smooth muscle contraction (GO:0014848)2.82165342
128negative regulation of chondrocyte differentiation (GO:0032331)2.81314680
129positive regulation of vesicle fusion (GO:0031340)2.81231605
130anterior/posterior axis specification, embryo (GO:0008595)2.81170782
131cellular response to amino acid stimulus (GO:0071230)2.80840077
132regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.78998269
133axon extension involved in axon guidance (GO:0048846)2.78531401
134neuron projection extension involved in neuron projection guidance (GO:1902284)2.78531401
135mechanosensory behavior (GO:0007638)2.78386187
136negative regulation of hormone metabolic process (GO:0032351)2.78211248
137negative regulation of smooth muscle cell migration (GO:0014912)2.78076038
138regulation of voltage-gated calcium channel activity (GO:1901385)2.77550466
139regulation of synaptic transmission, glutamatergic (GO:0051966)2.77412516
140regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.77283538
141chondrocyte development (GO:0002063)2.77103885
142regulation of female receptivity (GO:0045924)2.76828166
143behavioral response to cocaine (GO:0048148)2.76628143
144extracellular negative regulation of signal transduction (GO:1900116)2.76430809
145extracellular regulation of signal transduction (GO:1900115)2.76430809
146sleep (GO:0030431)2.75537731
147membrane assembly (GO:0071709)2.75509379
148long term synaptic depression (GO:0060292)2.75460002
149regulation of heart morphogenesis (GO:2000826)2.73749470
150face morphogenesis (GO:0060325)2.72615431
151regulation of vesicle fusion (GO:0031338)2.72467236
152positive regulation of mesenchymal cell proliferation (GO:0002053)2.71986977
153regulation of cardiac muscle cell differentiation (GO:2000725)2.71402993
154gonadal mesoderm development (GO:0007506)2.71029434
155negative regulation of neurotransmitter transport (GO:0051589)2.70786955
156outflow tract septum morphogenesis (GO:0003148)2.70569055
157regulation of respiratory system process (GO:0044065)2.69511315
158negative regulation of activin receptor signaling pathway (GO:0032926)2.68257440
159regulation of dendritic spine development (GO:0060998)2.67582401
160fibroblast migration (GO:0010761)2.67505635
161substrate adhesion-dependent cell spreading (GO:0034446)2.67372751
162extracellular matrix organization (GO:0030198)2.66410267
163extracellular structure organization (GO:0043062)2.65533319
164non-canonical Wnt signaling pathway (GO:0035567)2.65320091
165positive regulation of cardiac muscle hypertrophy (GO:0010613)2.65296810
166positive regulation of muscle hypertrophy (GO:0014742)2.65296810
167membrane depolarization (GO:0051899)2.63424747
168endocardial cushion morphogenesis (GO:0003203)2.62899034
169response to gravity (GO:0009629)2.61910303
170G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.61672206
171female mating behavior (GO:0060180)2.61379018
172regulation of neurotransmitter transport (GO:0051588)2.61016030
173endothelial cell morphogenesis (GO:0001886)2.59355086
174opioid receptor signaling pathway (GO:0038003)2.58650938
175regulation of dendritic spine morphogenesis (GO:0061001)2.58421650
176type B pancreatic cell development (GO:0003323)2.57491583
177cochlea development (GO:0090102)2.57202709
178inner ear receptor cell development (GO:0060119)2.53837731
179cell migration involved in sprouting angiogenesis (GO:0002042)2.53614734
180regulation of inositol phosphate biosynthetic process (GO:0010919)2.53404419
181negative regulation of amino acid transport (GO:0051956)2.53262130
182regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.53261061
183neurotransmitter secretion (GO:0007269)2.53168726
184negative regulation of catenin import into nucleus (GO:0035414)2.53162779
185muscle cell migration (GO:0014812)2.53061364
186negative regulation of axon guidance (GO:1902668)2.52368530
187membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.52112823
188positive regulation of meiosis (GO:0045836)2.52048261
189cardiac epithelial to mesenchymal transition (GO:0060317)2.51945160
190positive regulation of protein autophosphorylation (GO:0031954)2.51050749
191regulation of gastrulation (GO:0010470)2.50568918

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.96904227
2GBX2_23144817_ChIP-Seq_PC3_Human4.88318314
3PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse4.09048293
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.08042118
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.03415827
6SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.92772714
7EED_16625203_ChIP-ChIP_MESCs_Mouse2.73962801
8SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.73498730
9JARID2_20064375_ChIP-Seq_MESCs_Mouse2.72256507
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.65412099
11EZH2_18974828_ChIP-Seq_MESCs_Mouse2.65412099
12RARG_19884340_ChIP-ChIP_MEFs_Mouse2.58352160
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.49816607
14BRD4_25478319_ChIP-Seq_HGPS_Human2.44657509
15SMAD_19615063_ChIP-ChIP_OVARY_Human2.43191498
16ZFP57_27257070_Chip-Seq_ESCs_Mouse2.41165006
17JARID2_20075857_ChIP-Seq_MESCs_Mouse2.41154083
18AR_21572438_ChIP-Seq_LNCaP_Human2.30637530
19CJUN_26792858_Chip-Seq_BT549_Human2.28876710
20FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.28452345
21EZH2_27304074_Chip-Seq_ESCs_Mouse2.23711277
22CTBP2_25329375_ChIP-Seq_LNCAP_Human2.22249882
23MTF2_20144788_ChIP-Seq_MESCs_Mouse2.22189560
24TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.16084017
25TAF15_26573619_Chip-Seq_HEK293_Human2.14821174
26* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.07398883
27CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.03487495
28P300_19829295_ChIP-Seq_ESCs_Human2.02634654
29POU3F2_20337985_ChIP-ChIP_501MEL_Human2.01621539
30CTBP1_25329375_ChIP-Seq_LNCAP_Human2.01033637
31RNF2_27304074_Chip-Seq_ESCs_Mouse1.98502517
32HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.97525180
33SMAD4_21799915_ChIP-Seq_A2780_Human1.91478142
34TRIM28_21343339_ChIP-Seq_HEK293_Human1.91084406
35DROSHA_22980978_ChIP-Seq_HELA_Human1.90243785
36TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.88998104
37FUS_26573619_Chip-Seq_HEK293_Human1.88785413
38GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.87716297
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.87239836
40SUZ12_27294783_Chip-Seq_ESCs_Mouse1.82821471
41RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.80994323
42EZH2_27294783_Chip-Seq_ESCs_Mouse1.75215883
43TP53_18474530_ChIP-ChIP_U2OS_Human1.72533944
44SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.71300636
45PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.70007556
46REST_21632747_ChIP-Seq_MESCs_Mouse1.65205529
47VDR_22108803_ChIP-Seq_LS180_Human1.62537987
48PIAS1_25552417_ChIP-Seq_VCAP_Human1.59667154
49SMAD3_21741376_ChIP-Seq_EPCs_Human1.58934180
50SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.56679454
51AR_25329375_ChIP-Seq_VCAP_Human1.55442765
52TOP2B_26459242_ChIP-Seq_MCF-7_Human1.53971102
53* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.49616289
54BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.48260982
55TP53_16413492_ChIP-PET_HCT116_Human1.46879553
56IKZF1_21737484_ChIP-ChIP_HCT116_Human1.43050396
57OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.41784207
58CBX2_27304074_Chip-Seq_ESCs_Mouse1.41756160
59BMI1_23680149_ChIP-Seq_NPCS_Mouse1.41253037
60* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.41098261
61GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.37725696
62UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.34618140
63BCAT_22108803_ChIP-Seq_LS180_Human1.32767621
64NR3C1_23031785_ChIP-Seq_PC12_Mouse1.32746583
65SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.32659974
66FLI1_27457419_Chip-Seq_LIVER_Mouse1.32590320
67NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.30116429
68NRF2_20460467_ChIP-Seq_MEFs_Mouse1.30116429
69PCGF2_27294783_Chip-Seq_ESCs_Mouse1.29839686
70NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.28266736
71RARB_27405468_Chip-Seq_BRAIN_Mouse1.28226064
72ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.27648260
73ZNF217_24962896_ChIP-Seq_MCF-7_Human1.26758561
74ER_23166858_ChIP-Seq_MCF-7_Human1.26518458
75TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.26454283
76SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25586275
77NANOG_18555785_Chip-Seq_ESCs_Mouse1.24624994
78TBX3_20139965_ChIP-Seq_MESCs_Mouse1.24019047
79TBX3_20139965_ChIP-Seq_ESCs_Mouse1.23921052
80* SOX2_21211035_ChIP-Seq_LN229_Gbm1.23543587
81AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.23363373
82CDX2_19796622_ChIP-Seq_MESCs_Mouse1.23258377
83PCGF2_27294783_Chip-Seq_NPCs_Mouse1.22388525
84MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.22188632
85TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.20773368
86REST_18959480_ChIP-ChIP_MESCs_Mouse1.19040945
87WT1_19549856_ChIP-ChIP_CCG9911_Human1.19026431
88EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.18804670
89PRDM14_20953172_ChIP-Seq_ESCs_Human1.18670721
90ARNT_22903824_ChIP-Seq_MCF-7_Human1.18549419
91IGF1R_20145208_ChIP-Seq_DFB_Human1.17054390
92EWS_26573619_Chip-Seq_HEK293_Human1.16539471
93TCF4_23295773_ChIP-Seq_U87_Human1.16411133
94EZH2_27294783_Chip-Seq_NPCs_Mouse1.14200006
95JUN_21703547_ChIP-Seq_K562_Human1.13719405
96PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.12763936
97STAT3_23295773_ChIP-Seq_U87_Human1.12521598
98TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.12448997
99CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.11748248
100SA1_22415368_ChIP-Seq_MEFs_Mouse1.11571512
101E2F1_18555785_Chip-Seq_ESCs_Mouse1.11102206
102P53_22387025_ChIP-Seq_ESCs_Mouse1.10740004
103NR3C1_21868756_ChIP-Seq_MCF10A_Human1.10481962
104EP300_21415370_ChIP-Seq_HL-1_Mouse1.10108653
105RING1B_27294783_Chip-Seq_ESCs_Mouse1.08617993
106SUZ12_27294783_Chip-Seq_NPCs_Mouse1.06649836
107AHR_22903824_ChIP-Seq_MCF-7_Human1.05974406
108ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.05903417
109RBPJ_22232070_ChIP-Seq_NCS_Mouse1.05436493
110CLOCK_20551151_ChIP-Seq_293T_Human1.05295194
111KDM2B_26808549_Chip-Seq_REH_Human1.05194733
112SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.04864732
113TP53_20018659_ChIP-ChIP_R1E_Mouse1.04615872
114RXR_22108803_ChIP-Seq_LS180_Human1.04009268
115RUNX2_22187159_ChIP-Seq_PCA_Human1.03983066
116TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03487091
117POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.03487091
118WT1_25993318_ChIP-Seq_PODOCYTE_Human1.02834508
119WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.02680373
120CMYC_18555785_Chip-Seq_ESCs_Mouse1.02244231
121ISL1_27105846_Chip-Seq_CPCs_Mouse1.00653964
122POU5F1_16153702_ChIP-ChIP_HESCs_Human0.99608537
123SOX2_20726797_ChIP-Seq_SW620_Human0.98787246
124CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98474647
125MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.97775775
126MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.97535277
127SALL4_18804426_ChIP-ChIP_XEN_Mouse0.96171977
128RING1B_27294783_Chip-Seq_NPCs_Mouse0.95753570
129SMC1_22415368_ChIP-Seq_MEFs_Mouse0.95213800
130* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.92914532
131JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.92775103
132FOXM1_26456572_ChIP-Seq_MCF-7_Human0.92524808
133KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.90935132
134PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.89440874
135* CRX_20693478_ChIP-Seq_RETINA_Mouse0.88965259

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005503_abnormal_tendon_morphology5.89624539
2MP0008438_abnormal_cutaneous_collagen5.58259902
3MP0003880_abnormal_central_pattern5.10201128
4MP0004859_abnormal_synaptic_plasticity4.80842034
5MP0005275_abnormal_skin_tensile4.18769881
6MP0006054_spinal_hemorrhage3.17363192
7MP0003879_abnormal_hair_cell2.99489690
8MP0002736_abnormal_nociception_after2.93800880
9MP0001968_abnormal_touch/_nociception2.84835229
10MP0003635_abnormal_synaptic_transmissio2.82092138
11MP0003705_abnormal_hypodermis_morpholog2.49762514
12MP0010030_abnormal_orbit_morphology2.44456955
13MP0009745_abnormal_behavioral_response2.39324481
14MP0002063_abnormal_learning/memory/cond2.38637818
15MP0009384_cardiac_valve_regurgitation2.19935286
16MP0009780_abnormal_chondrocyte_physiolo2.06730154
17MP0002064_seizures2.06150594
18MP0002572_abnormal_emotion/affect_behav2.03466458
19MP0009046_muscle_twitch2.00819894
20MP0010368_abnormal_lymphatic_system1.91059344
21MP0001188_hyperpigmentation1.86057606
22MP0002876_abnormal_thyroid_physiology1.84584271
23MP0005171_absent_coat_pigmentation1.81671200
24MP0001501_abnormal_sleep_pattern1.81420289
25MP0002837_dystrophic_cardiac_calcinosis1.77156494
26MP0002108_abnormal_muscle_morphology1.74760879
27MP0004270_analgesia1.74668338
28MP0002272_abnormal_nervous_system1.73912389
29MP0003941_abnormal_skin_development1.72122883
30MP0000767_abnormal_smooth_muscle1.69099408
31MP0001486_abnormal_startle_reflex1.64883809
32MP0003942_abnormal_urinary_system1.61683458
33MP0005646_abnormal_pituitary_gland1.58685674
34MP0003950_abnormal_plasma_membrane1.58591519
35MP0003283_abnormal_digestive_organ1.58391863
36MP0003122_maternal_imprinting1.53044493
37MP0004484_altered_response_of1.52007251
38MP0005508_abnormal_skeleton_morphology1.50542016
39MP0000751_myopathy1.48660690
40MP0000569_abnormal_digit_pigmentation1.47146182
41MP0002896_abnormal_bone_mineralization1.43563279
42MP0002735_abnormal_chemical_nociception1.41678100
43MP0002067_abnormal_sensory_capabilities1.41204140
44MP0003566_abnormal_cell_adhesion1.38237444
45MP0003787_abnormal_imprinting1.34759425
46MP0001661_extended_life_span1.34645963
47MP0003136_yellow_coat_color1.34341692
48MP0003646_muscle_fatigue1.33812452
49MP0001958_emphysema1.29278838
50MP0006276_abnormal_autonomic_nervous1.27452306
51MP0002734_abnormal_mechanical_nocicepti1.24695919
52MP0004233_abnormal_muscle_weight1.19350018
53MP0001440_abnormal_grooming_behavior1.19149749
54MP0000428_abnormal_craniofacial_morphol1.18750785
55MP0005623_abnormal_meninges_morphology1.16758547
56MP0003279_aneurysm1.16067429
57MP0005023_abnormal_wound_healing1.14572683
58MP0000681_abnormal_thyroid_gland1.12884841
59MP0010386_abnormal_urinary_bladder1.12663421
60MP0010352_gastrointestinal_tract_polyps1.12559158
61MP0009379_abnormal_foot_pigmentation1.11606033
62MP0002060_abnormal_skin_morphology1.09422952
63MP0000013_abnormal_adipose_tissue1.09208708
64MP0002184_abnormal_innervation1.07560162
65MP0001879_abnormal_lymphatic_vessel1.07524680
66MP0003385_abnormal_body_wall1.06965761
67MP0000678_abnormal_parathyroid_gland1.06909876
68MP0000762_abnormal_tongue_morphology1.06036048
69MP0008004_abnormal_stomach_pH1.05371194
70MP0004145_abnormal_muscle_electrophysio1.04997710
71MP0008569_lethality_at_weaning1.04904815
72MP0003755_abnormal_palate_morphology1.04403187
73MP0000462_abnormal_digestive_system1.03878540
74MP0002102_abnormal_ear_morphology1.01625419
75MP0004272_abnormal_basement_membrane1.01616725
76MP0009250_abnormal_appendicular_skeleto1.00648477
77MP0001963_abnormal_hearing_physiology0.99566561
78MP0002932_abnormal_joint_morphology0.98875232
79MP0005595_abnormal_vascular_smooth0.98090669
80MP0005386_behavior/neurological_phenoty0.97736507
81MP0004924_abnormal_behavior0.97736507
82MP0002254_reproductive_system_inflammat0.97132175
83MP0002295_abnormal_pulmonary_circulatio0.95905678
84MP0005197_abnormal_uvea_morphology0.95520607
85MP0000516_abnormal_urinary_system0.93417545
86MP0005367_renal/urinary_system_phenotyp0.93417545
87MP0000538_abnormal_urinary_bladder0.92981412
88MP0009697_abnormal_copulation0.92133560
89MP0002557_abnormal_social/conspecific_i0.91092710
90MP0001177_atelectasis0.88471032
91MP0005084_abnormal_gallbladder_morpholo0.88278296
92MP0005423_abnormal_somatic_nervous0.87904841
93MP0000749_muscle_degeneration0.86976690
94MP0003935_abnormal_craniofacial_develop0.86712158
95MP0000778_abnormal_nervous_system0.86403383
96MP0001502_abnormal_circadian_rhythm0.86280292
97MP0002177_abnormal_outer_ear0.85988686
98MP0005257_abnormal_intraocular_pressure0.85084875
99MP0002109_abnormal_limb_morphology0.84892756
100MP0002938_white_spotting0.84588560
101MP0003091_abnormal_cell_migration0.82999597
102MP0003937_abnormal_limbs/digits/tail_de0.82882838
103MP0000049_abnormal_middle_ear0.82062499
104MP0000432_abnormal_head_morphology0.81902148
105MP0000026_abnormal_inner_ear0.81752195
106MP0002116_abnormal_craniofacial_bone0.81462820
107MP0000733_abnormal_muscle_development0.80997963
108MP0000015_abnormal_ear_pigmentation0.80075407
109MP0001970_abnormal_pain_threshold0.79538593
110MP0001756_abnormal_urination0.78773002
111MP0005390_skeleton_phenotype0.78421477
112MP0002160_abnormal_reproductive_system0.77230507
113MP0001905_abnormal_dopamine_level0.76832616
114MP0005193_abnormal_anterior_eye0.76392457
115MP0002249_abnormal_larynx_morphology0.76330604
116MP0001243_abnormal_dermal_layer0.76226727
117MP0002933_joint_inflammation0.75456909
118MP0002128_abnormal_blood_circulation0.74771926
119MP0001542_abnormal_bone_strength0.74172429
120MP0000534_abnormal_ureter_morphology0.73957353
121MP0002114_abnormal_axial_skeleton0.73584307
122MP0003075_altered_response_to0.72797745
123MP0002233_abnormal_nose_morphology0.72786851
124MP0002009_preneoplasia0.72426490
125MP0004811_abnormal_neuron_physiology0.72011003
126MP0000759_abnormal_skeletal_muscle0.71805269
127MP0002115_abnormal_skeleton_extremities0.70751342
128MP0004858_abnormal_nervous_system0.69930936
129MP0006072_abnormal_retinal_apoptosis0.69847717
130MP0000613_abnormal_salivary_gland0.69803639
131MP0000163_abnormal_cartilage_morphology0.69563352
132MP0002733_abnormal_thermal_nociception0.68289155
133MP0005620_abnormal_muscle_contractility0.66750439
134MP0002066_abnormal_motor_capabilities/c0.66505502
135MP0000003_abnormal_adipose_tissue0.65496875
136MP0002163_abnormal_gland_morphology0.64379829
137MP0010771_integument_phenotype0.64345673
138MP0002089_abnormal_postnatal_growth/wei0.63731719
139MP0004134_abnormal_chest_morphology0.63642210
140MP0001529_abnormal_vocalization0.62392318
141MP0002882_abnormal_neuron_morphology0.61792972
142MP0001664_abnormal_digestion0.60917607
143MP0005164_abnormal_response_to0.60861550
144MP0001299_abnormal_eye_distance/0.60325545
145MP0000631_abnormal_neuroendocrine_gland0.59705321
146MP0005369_muscle_phenotype0.59606665
147MP0002998_abnormal_bone_remodeling0.59583217
148MP0002113_abnormal_skeleton_development0.59431929
149MP0009053_abnormal_anal_canal0.59275876
150MP0001614_abnormal_blood_vessel0.58960701
151MP0003115_abnormal_respiratory_system0.58403272
152MP0002168_other_aberrant_phenotype0.57356087
153MP0002282_abnormal_trachea_morphology0.57232109
154MP0001175_abnormal_lung_morphology0.56231262
155MP0004084_abnormal_cardiac_muscle0.55234607
156MP0004885_abnormal_endolymph0.53419596
157MP0002090_abnormal_vision0.51994307
158MP0003186_abnormal_redox_activity0.51920312
159MP0003119_abnormal_digestive_system0.51850490
160MP0003795_abnormal_bone_structure0.51477854
161MP0001270_distended_abdomen0.50953375
162MP0005220_abnormal_exocrine_pancreas0.49860908
163MP0004036_abnormal_muscle_relaxation0.49437696
164MP0000639_abnormal_adrenal_gland0.49317579

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.99117672
2Protrusio acetabuli (HP:0003179)6.33526940
3Epileptic encephalopathy (HP:0200134)4.80700996
4Cervical subluxation (HP:0003308)4.65137890
5Hyperventilation (HP:0002883)4.62652258
6Bladder diverticulum (HP:0000015)4.50296756
7Ankle contracture (HP:0006466)4.42365113
8Atonic seizures (HP:0010819)4.20662856
9Focal seizures (HP:0007359)4.06872193
10Broad metatarsal (HP:0001783)4.01672281
11Follicular hyperkeratosis (HP:0007502)3.86475171
12Febrile seizures (HP:0002373)3.66084246
13Wrist flexion contracture (HP:0001239)3.59626663
14Peritonitis (HP:0002586)3.48280143
15Shallow orbits (HP:0000586)3.46230481
16Dilatation of the ascending aorta (HP:0005111)3.46189567
17Premature rupture of membranes (HP:0001788)3.41959005
18Bowel diverticulosis (HP:0005222)3.40709298
19Narrow nasal bridge (HP:0000446)3.39861302
20Vertebral compression fractures (HP:0002953)3.22219553
21Broad-based gait (HP:0002136)3.20494632
22Absent frontal sinuses (HP:0002688)3.18827985
23Visual hallucinations (HP:0002367)3.02746230
24Slender build (HP:0001533)3.01654456
25Bell-shaped thorax (HP:0001591)2.96334807
26Absence seizures (HP:0002121)2.95575605
27Spondylolisthesis (HP:0003302)2.93476719
28Round ear (HP:0100830)2.88760471
29Blue sclerae (HP:0000592)2.79872804
30Coronal craniosynostosis (HP:0004440)2.76042779
31Infantile muscular hypotonia (HP:0008947)2.74891435
32Deformed tarsal bones (HP:0008119)2.68973812
33Calcaneovalgus deformity (HP:0001848)2.67873437
34Protruding tongue (HP:0010808)2.67012641
35Dialeptic seizures (HP:0011146)2.66719704
36Keratoconus (HP:0000563)2.65195825
37Increased corneal curvature (HP:0100692)2.65195825
38Type 1 muscle fiber predominance (HP:0003803)2.65082600
39Abnormal delivery (HP:0001787)2.64825001
40Gaze-evoked nystagmus (HP:0000640)2.60520855
41Amblyopia (HP:0000646)2.59032731
42Neonatal short-limb short stature (HP:0008921)2.58599754
43Aortic valve stenosis (HP:0001650)2.57014628
44Abnormality of dentin (HP:0010299)2.54691994
45Wide anterior fontanel (HP:0000260)2.42101085
46Action tremor (HP:0002345)2.40236159
47Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.38895506
48Aortic regurgitation (HP:0001659)2.38645933
49Aortic dissection (HP:0002647)2.38204224
50Corneal dystrophy (HP:0001131)2.36878070
51Generalized tonic-clonic seizures (HP:0002069)2.33569311
52Vascular tortuosity (HP:0004948)2.32105065
53Biconcave vertebral bodies (HP:0004586)2.30888717
54Deviation of the hallux (HP:0010051)2.30627481
55Joint stiffness (HP:0001387)2.30103868
56Cardiovascular calcification (HP:0011915)2.26542506
57Spinal canal stenosis (HP:0003416)2.22665126
58Osteoarthritis (HP:0002758)2.22622422
59Bulbous nose (HP:0000414)2.22568304
60Delayed gross motor development (HP:0002194)2.19836994
61Hydroureter (HP:0000072)2.19401966
62Poor eye contact (HP:0000817)2.17167766
63Ankyloglossia (HP:0010296)2.15912481
64Progressive cerebellar ataxia (HP:0002073)2.15437583
65Obstructive sleep apnea (HP:0002870)2.14489118
66Breech presentation (HP:0001623)2.13086576
67Genu recurvatum (HP:0002816)2.12464775
68Broad ribs (HP:0000885)2.12403768
69Cerebral aneurysm (HP:0004944)2.11461071
70Mitral stenosis (HP:0001718)2.10389249
71Mild short stature (HP:0003502)2.09506380
72Conical tooth (HP:0000698)2.09404446
73Abnormality of the acetabulum (HP:0003170)2.09193742
74Hallux valgus (HP:0001822)2.08465741
75Abnormality of the frontal sinuses (HP:0002687)2.07928650
76Ectopia lentis (HP:0001083)2.07800689
77Short hallux (HP:0010109)2.07263649
78Soft skin (HP:0000977)2.06203189
79Increased variability in muscle fiber diameter (HP:0003557)2.06031622
80Stereotypic behavior (HP:0000733)2.05753762
81Turricephaly (HP:0000262)2.04636600
82Hypoventilation (HP:0002791)2.03764442
83Mitral valve prolapse (HP:0001634)2.00386740
84Osteolytic defects of the phalanges of the hand (HP:0009771)1.99761288
85Osteolytic defects of the hand bones (HP:0009699)1.99761288
86Spinal rigidity (HP:0003306)1.98071135
87Drooling (HP:0002307)1.96834143
88Excessive salivation (HP:0003781)1.96834143
89Impaired smooth pursuit (HP:0007772)1.96019765
90Limited hip movement (HP:0008800)1.95587132
91J-shaped sella turcica (HP:0002680)1.95525326
92Congenital glaucoma (HP:0001087)1.94735931
93Abnormality of the parietal bone (HP:0002696)1.94513382
94Mesomelia (HP:0003027)1.93816074
95Aplasia/Hypoplasia of the hallux (HP:0008362)1.93426119
96Deeply set eye (HP:0000490)1.91825165
97Atrophic scars (HP:0001075)1.91450990
98Mildly elevated creatine phosphokinase (HP:0008180)1.91037368
99Fragile skin (HP:0001030)1.90845494
100Hypoplastic ischia (HP:0003175)1.90768434
101Delusions (HP:0000746)1.89869417
102Abnormal eating behavior (HP:0100738)1.89865525
103Palpebral edema (HP:0100540)1.89277789
104Redundant skin (HP:0001582)1.88851164
105Hyperextensible skin (HP:0000974)1.88577061
106Heterochromia iridis (HP:0001100)1.88032325
107Testicular atrophy (HP:0000029)1.87516328
108Elbow flexion contracture (HP:0002987)1.86422549
109Buphthalmos (HP:0000557)1.84926001
110Spinal cord lesions (HP:0100561)1.84827464
111Syringomyelia (HP:0003396)1.84827464
112Flat cornea (HP:0007720)1.84223547
113Striae distensae (HP:0001065)1.84159144
114Ulnar bowing (HP:0003031)1.83992052
115Epileptiform EEG discharges (HP:0011182)1.83816220
116Absent phalangeal crease (HP:0006109)1.83485578
117Gingival overgrowth (HP:0000212)1.82649970
118Inguinal hernia (HP:0000023)1.82145916
119Abnormality of oral frenula (HP:0000190)1.81591102
120Aneurysm (HP:0002617)1.81235074
121Ulnar deviation of the wrist (HP:0003049)1.80379058
122Arterial tortuosity (HP:0005116)1.80184118
123Pulmonary artery stenosis (HP:0004415)1.80075569
124Ovoid vertebral bodies (HP:0003300)1.80032970
125Mitral regurgitation (HP:0001653)1.79605668
126Joint laxity (HP:0001388)1.79151313
127Nonimmune hydrops fetalis (HP:0001790)1.78342917
128Wormian bones (HP:0002645)1.78220729
129Choroideremia (HP:0001139)1.77935828
130Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.76873260
131Anxiety (HP:0000739)1.76577927
132Unilateral renal agenesis (HP:0000122)1.76311285
133Partial duplication of the phalanx of hand (HP:0009999)1.75734069
134Aplasia of the musculature (HP:0100854)1.75480786
135Abnormality of ocular smooth pursuit (HP:0000617)1.73923117
136Protruding ear (HP:0000411)1.73602530
137Absent speech (HP:0001344)1.73151805
138Venous insufficiency (HP:0005293)1.71430954
139Hip contracture (HP:0003273)1.71331536
140Distal arthrogryposis (HP:0005684)1.69521303
141Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.69406379
142Hypoplasia of the odontoid process (HP:0003311)1.69120780
143Abnormality of skeletal muscle fiber size (HP:0012084)1.68636708
144Delayed closure of the anterior fontanelle (HP:0001476)1.68390881
145Camptodactyly of toe (HP:0001836)1.67405100
146Long toe (HP:0010511)1.67138947
147Dysdiadochokinesis (HP:0002075)1.67122102
148Absent/shortened dynein arms (HP:0200106)1.66468074
149Dynein arm defect of respiratory motile cilia (HP:0012255)1.66468074
150Overgrowth (HP:0001548)1.66088408
151Bulbar palsy (HP:0001283)1.65726816
152Abnormality of molar morphology (HP:0011070)1.65275676
153Abnormality of molar (HP:0011077)1.65275676
154Myokymia (HP:0002411)1.65064532
155Aortic aneurysm (HP:0004942)1.64396452
156Nuclear cataract (HP:0100018)1.64110225
157Distal lower limb amyotrophy (HP:0008944)1.63705972
158Impaired vibratory sensation (HP:0002495)1.63644525
159Limb-girdle muscle weakness (HP:0003325)1.63528618
160Hypoglycemic seizures (HP:0002173)1.63443168
161Dysmetric saccades (HP:0000641)1.62988202
162Osteopenia (HP:0000938)1.61861479

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.80134033
2EPHA45.24808347
3MAP2K73.91188763
4NTRK33.85368186
5RIPK43.02145052
6LIMK12.76907490
7TIE12.73728374
8BMPR22.65544127
9DAPK22.63448642
10PLK22.61378644
11CDK192.60172621
12MAP3K122.43533928
13PRPF4B2.36843890
14DAPK12.20511847
15PIK3CG2.18545996
16CCNB12.16566915
17PTK2B2.15502480
18TGFBR22.08888019
19FGFR22.07658719
20MAP3K42.03503391
21PTK21.98112717
22PAK21.96965854
23NME11.84277669
24NLK1.70450372
25AKT31.69499198
26DDR21.68451711
27NEK91.66426291
28PAK31.66311974
29GRK11.62597448
30ERBB31.45304865
31EPHB21.44053484
32LATS11.43914366
33PAK61.42450673
34TAF11.37987049
35MAP2K41.36540809
36TNIK1.35517042
37FLT31.31572720
38GRK51.31452297
39MAPKAPK31.30400292
40CAMKK21.28633967
41MET1.27490146
42STK31.23748029
43SIK11.23587804
44PRKD21.22450698
45TGFBR11.15298727
46MINK11.14124381
47TNK21.13832639
48STK381.13327962
49MAP3K21.07302775
50CAMK2A1.06673294
51TESK11.06128031
52SIK31.05600184
53MKNK21.02796184
54CDC42BPA0.99596546
55PDGFRB0.96295856
56ERBB40.94791969
57CAMKK10.94108380
58DAPK30.93789938
59PRKCG0.92413523
60CAMK2B0.92199831
61DMPK0.92184991
62MAPK130.91713096
63KSR10.91217542
64OXSR10.90882366
65CAMK10.90533704
66FER0.89604877
67NUAK10.87889774
68CDK50.86641313
69RIPK10.85670128
70MAPK70.85440787
71MOS0.84672868
72GSK3A0.81023160
73FGR0.79318647
74PRKD30.79278902
75BMPR1B0.78914965
76FRK0.78333262
77MELK0.75742966
78STK38L0.75050550
79CDK80.74510506
80SGK20.73165754
81RAF10.72951722
82ABL20.72765737
83PAK40.71031778
84PIK3CA0.70285532
85INSRR0.68718550
86FES0.67256175
87NTRK10.66013976
88ROCK20.65858048
89PRKCE0.65067957
90ACVR1B0.63850167
91MYLK0.63806133
92CDK180.62266694
93WNK10.62232681
94ADRBK10.60039927
95PRKG20.59142516
96MAP2K10.59100468
97MAP3K70.57685716
98MAPKAPK50.55933700
99TRPM70.55846121
100CDK150.55635832
101EEF2K0.55132862
102PINK10.54360012
103ERN10.54176864
104TSSK60.51901696
105CAMK2D0.51731053
106CSNK1G10.51712011
107DYRK1A0.51388038
108NEK60.50981461
109PASK0.48254112
110MAP2K60.48100381
111FGFR10.47916298
112JAK10.47401162
113ADRBK20.47394510
114CAMK40.46318597
115PDK40.45665703
116PDK30.45665703
117CDK11A0.45581705
118SGK2230.45424893
119SGK4940.45424893
120STK160.45139647
121LATS20.44943158
122CDK140.43595823
123PLK30.43376308
124PRKD10.42160062
125SGK10.41069510
126RPS6KA20.40125109
127MKNK10.39818865
128YES10.38238484
129STK240.37404066
130CDK30.37214706
131PRKCH0.36757149
132RPS6KB10.36374996
133PRKAA10.36236841
134TYK20.35734096
135MAP3K90.35716552
136MAPK120.35578504
137PDGFRA0.35572574
138PRKG10.34307817
139CAMK1G0.33307292
140SGK30.33220675
141FGFR30.32742711
142TTN0.32660087
143PIM20.32334134
144PRKAA20.31755055
145ARAF0.31448676
146BRAF0.30754826
147KIT0.30101029
148SYK0.29787041
149ROCK10.29741616
150EPHB10.29576939
151RPS6KL10.28887055
152RPS6KC10.28887055
153BRSK20.28831977
154NTRK20.28394884
155CAMK2G0.27321606
156MAP3K60.26096401
157ILK0.24092783
158PRKACA0.24090938
159GRK70.22485278
160PRKCA0.21891341

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.91384823
2Long-term potentiation_Homo sapiens_hsa047202.91121563
3Amphetamine addiction_Homo sapiens_hsa050312.79794430
4Synaptic vesicle cycle_Homo sapiens_hsa047212.75946760
5Maturity onset diabetes of the young_Homo sapiens_hsa049502.75195839
6Circadian entrainment_Homo sapiens_hsa047132.69490738
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.67909436
8Morphine addiction_Homo sapiens_hsa050322.42012726
9Sulfur metabolism_Homo sapiens_hsa009202.37995005
10Glutamatergic synapse_Homo sapiens_hsa047242.26519826
11Protein export_Homo sapiens_hsa030602.25102642
12Olfactory transduction_Homo sapiens_hsa047402.23183237
13Salivary secretion_Homo sapiens_hsa049702.20009396
14Basal cell carcinoma_Homo sapiens_hsa052172.07882382
15Hedgehog signaling pathway_Homo sapiens_hsa043402.01549996
16Dopaminergic synapse_Homo sapiens_hsa047281.96341930
17Taste transduction_Homo sapiens_hsa047421.93892209
18Calcium signaling pathway_Homo sapiens_hsa040201.91424827
19Renin secretion_Homo sapiens_hsa049241.90344403
20GABAergic synapse_Homo sapiens_hsa047271.87701757
21Selenocompound metabolism_Homo sapiens_hsa004501.83350461
22Collecting duct acid secretion_Homo sapiens_hsa049661.81471916
23Oxytocin signaling pathway_Homo sapiens_hsa049211.70276922
24Serotonergic synapse_Homo sapiens_hsa047261.68209919
25Cholinergic synapse_Homo sapiens_hsa047251.64947874
26Aldosterone synthesis and secretion_Homo sapiens_hsa049251.63479147
27Long-term depression_Homo sapiens_hsa047301.57683800
28Insulin secretion_Homo sapiens_hsa049111.55014163
29Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.54742928
30Glycosaminoglycan degradation_Homo sapiens_hsa005311.53068866
31Gastric acid secretion_Homo sapiens_hsa049711.48679448
32Fatty acid elongation_Homo sapiens_hsa000621.44671521
33Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.43188845
34Renin-angiotensin system_Homo sapiens_hsa046141.42384086
35Hippo signaling pathway_Homo sapiens_hsa043901.39908463
36Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.37136113
37ECM-receptor interaction_Homo sapiens_hsa045121.32302323
38cAMP signaling pathway_Homo sapiens_hsa040241.29730857
39Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.28734864
40GnRH signaling pathway_Homo sapiens_hsa049121.28225990
41Vibrio cholerae infection_Homo sapiens_hsa051101.26016869
42N-Glycan biosynthesis_Homo sapiens_hsa005101.21432347
43Glioma_Homo sapiens_hsa052141.21428535
44cGMP-PKG signaling pathway_Homo sapiens_hsa040221.17375968
45Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.16330597
46Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.13659913
47Regulation of autophagy_Homo sapiens_hsa041401.11863772
48Cocaine addiction_Homo sapiens_hsa050301.11124122
49Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.10690076
50Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.09718355
51Estrogen signaling pathway_Homo sapiens_hsa049151.08548291
52Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.07374007
53Axon guidance_Homo sapiens_hsa043601.06503113
54Dilated cardiomyopathy_Homo sapiens_hsa054141.04482051
55African trypanosomiasis_Homo sapiens_hsa051431.04399091
56Gap junction_Homo sapiens_hsa045401.04158970
57Rheumatoid arthritis_Homo sapiens_hsa053231.03116872
58Vascular smooth muscle contraction_Homo sapiens_hsa042701.01990641
59Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.98763715
60Melanogenesis_Homo sapiens_hsa049160.97936240
61Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.97749547
62Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.97131855
63ErbB signaling pathway_Homo sapiens_hsa040120.96257033
64Mineral absorption_Homo sapiens_hsa049780.95042005
65Focal adhesion_Homo sapiens_hsa045100.93879799
66Phosphatidylinositol signaling system_Homo sapiens_hsa040700.88298479
67SNARE interactions in vesicular transport_Homo sapiens_hsa041300.88233305
68MAPK signaling pathway_Homo sapiens_hsa040100.87516454
69Small cell lung cancer_Homo sapiens_hsa052220.87087827
70Pathways in cancer_Homo sapiens_hsa052000.87078341
71Ras signaling pathway_Homo sapiens_hsa040140.86805580
72Alzheimers disease_Homo sapiens_hsa050100.86576402
73Adherens junction_Homo sapiens_hsa045200.86368576
74Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.85444127
75Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.83302843
76AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.83016453
77Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.82618880
78Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.82305885
79Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.81671807
80Vitamin B6 metabolism_Homo sapiens_hsa007500.80559209
81Complement and coagulation cascades_Homo sapiens_hsa046100.80065797
82Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.79470986
83Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.78795803
84Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.77545153
85Phototransduction_Homo sapiens_hsa047440.77014185
86Rap1 signaling pathway_Homo sapiens_hsa040150.73802072
87One carbon pool by folate_Homo sapiens_hsa006700.71057251
88Cardiac muscle contraction_Homo sapiens_hsa042600.70699274
89Neurotrophin signaling pathway_Homo sapiens_hsa047220.70274588
90Protein digestion and absorption_Homo sapiens_hsa049740.68708115
91Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.68569819
92Glucagon signaling pathway_Homo sapiens_hsa049220.67220432
93Propanoate metabolism_Homo sapiens_hsa006400.66731256
94Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.65390921
95Glutathione metabolism_Homo sapiens_hsa004800.63479012
96Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.63144636
97Phagosome_Homo sapiens_hsa041450.62804465
98Oxidative phosphorylation_Homo sapiens_hsa001900.62544166
99Tryptophan metabolism_Homo sapiens_hsa003800.61763815
100Tight junction_Homo sapiens_hsa045300.59745071
101Amoebiasis_Homo sapiens_hsa051460.59055357
102Lysosome_Homo sapiens_hsa041420.58993402
103Melanoma_Homo sapiens_hsa052180.58463332
104Tuberculosis_Homo sapiens_hsa051520.58216718
105mTOR signaling pathway_Homo sapiens_hsa041500.58022987
106Folate biosynthesis_Homo sapiens_hsa007900.56972222
107Thyroid hormone synthesis_Homo sapiens_hsa049180.56598331
108Regulation of actin cytoskeleton_Homo sapiens_hsa048100.56339717
109Pancreatic secretion_Homo sapiens_hsa049720.56230750
110Butanoate metabolism_Homo sapiens_hsa006500.54996381
111TGF-beta signaling pathway_Homo sapiens_hsa043500.54657996
112Shigellosis_Homo sapiens_hsa051310.54494481
113Type II diabetes mellitus_Homo sapiens_hsa049300.54118117
114Primary bile acid biosynthesis_Homo sapiens_hsa001200.53835990
115Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.52934842
116Wnt signaling pathway_Homo sapiens_hsa043100.52793779
117Sphingolipid metabolism_Homo sapiens_hsa006000.52342126
118Prostate cancer_Homo sapiens_hsa052150.51707051
119Choline metabolism in cancer_Homo sapiens_hsa052310.51520257
120Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.51345080
121Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.51242292
122Circadian rhythm_Homo sapiens_hsa047100.51068271
123Proteoglycans in cancer_Homo sapiens_hsa052050.50875879
124Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.49850456
125Lysine degradation_Homo sapiens_hsa003100.49583090
126Phospholipase D signaling pathway_Homo sapiens_hsa040720.49207688
127Ovarian steroidogenesis_Homo sapiens_hsa049130.46526273
128Malaria_Homo sapiens_hsa051440.44959513
129AMPK signaling pathway_Homo sapiens_hsa041520.44843572
130PI3K-Akt signaling pathway_Homo sapiens_hsa041510.44763877
131Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.44096958
132Oocyte meiosis_Homo sapiens_hsa041140.43846571
133MicroRNAs in cancer_Homo sapiens_hsa052060.43247662
134p53 signaling pathway_Homo sapiens_hsa041150.40630688
135Insulin resistance_Homo sapiens_hsa049310.40201901
136Basal transcription factors_Homo sapiens_hsa030220.40156196
137Longevity regulating pathway - mammal_Homo sapiens_hsa042110.39233237
138Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.38527511
139Insulin signaling pathway_Homo sapiens_hsa049100.36470777
140Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.35825312
141Dorso-ventral axis formation_Homo sapiens_hsa043200.35453284
142VEGF signaling pathway_Homo sapiens_hsa043700.35429288
143Platelet activation_Homo sapiens_hsa046110.35382289
144Fatty acid degradation_Homo sapiens_hsa000710.35379271
145Retinol metabolism_Homo sapiens_hsa008300.35090118
146TNF signaling pathway_Homo sapiens_hsa046680.33175410
147Chemokine signaling pathway_Homo sapiens_hsa040620.32418331
148Alcoholism_Homo sapiens_hsa050340.31246068
149Salmonella infection_Homo sapiens_hsa051320.30636337

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