GALNTL5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement (GO:0003351)9.54978186
2axonemal dynein complex assembly (GO:0070286)9.45104523
3motile cilium assembly (GO:0044458)8.56471085
4cilium movement (GO:0003341)8.17849332
5sperm capacitation (GO:0048240)8.06897090
6single fertilization (GO:0007338)8.01118120
7spermatid nucleus differentiation (GO:0007289)7.98814036
8* spermatid development (GO:0007286)7.79287756
9male meiosis (GO:0007140)7.74262277
10epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.33482868
11regulation of cilium movement (GO:0003352)7.14559283
12synaptonemal complex assembly (GO:0007130)7.00640573
13synaptonemal complex organization (GO:0070193)6.84957859
14response to pheromone (GO:0019236)6.74701736
15fertilization (GO:0009566)6.21813085
16piRNA metabolic process (GO:0034587)5.89331538
17cell recognition (GO:0008037)5.56224936
18spermatogenesis (GO:0007283)5.36706509
19male gamete generation (GO:0048232)5.34577475
20microtubule depolymerization (GO:0007019)5.31696274
21calcium ion-dependent exocytosis (GO:0017156)5.31109268
22ventricular system development (GO:0021591)5.28466405
23organic cation transport (GO:0015695)5.20752780
24microtubule severing (GO:0051013)5.09530110
25negative regulation of inclusion body assembly (GO:0090084)4.97780563
26gamete generation (GO:0007276)4.92759734
27chromosome organization involved in meiosis (GO:0070192)4.86656879
28* cellular process involved in reproduction in multicellular organism (GO:0022412)4.78746500
29cellular ketone body metabolic process (GO:0046950)4.66402811
30sexual reproduction (GO:0019953)4.65464471
31monoubiquitinated protein deubiquitination (GO:0035520)4.57047925
32single strand break repair (GO:0000012)4.39158522
33establishment of protein localization to Golgi (GO:0072600)4.38832673
34regulation of inclusion body assembly (GO:0090083)4.37379767
35* germ cell development (GO:0007281)4.27297580
36ketone body metabolic process (GO:1902224)4.21715197
37meiotic nuclear division (GO:0007126)4.20779582
38protein K11-linked deubiquitination (GO:0035871)4.17726260
39protein targeting to Golgi (GO:0000042)4.17670828
40regulation of microtubule-based movement (GO:0060632)4.11664267
41glycerol ether metabolic process (GO:0006662)4.01314628
42multicellular organismal reproductive process (GO:0048609)3.86618900
43rRNA methylation (GO:0031167)3.84572033
44protein polyglutamylation (GO:0018095)3.83460594
45DNA methylation involved in gamete generation (GO:0043046)3.82261247
46retrograde transport, vesicle recycling within Golgi (GO:0000301)3.79930472
47phosphatidylethanolamine biosynthetic process (GO:0006646)3.72842567
48ether metabolic process (GO:0018904)3.70560915
49male meiosis I (GO:0007141)3.66715422
50phosphatidylethanolamine metabolic process (GO:0046337)3.59488831
51detection of light stimulus involved in sensory perception (GO:0050962)3.53737486
52detection of light stimulus involved in visual perception (GO:0050908)3.53737486
53centriole assembly (GO:0098534)3.51720708
54centriole replication (GO:0007099)3.43502288
55rRNA modification (GO:0000154)3.41328293
56photoreceptor cell maintenance (GO:0045494)3.33777979
57protein localization to Golgi apparatus (GO:0034067)3.33637080
58positive regulation of macrophage activation (GO:0043032)3.27396194
59detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.26836277
60DNA double-strand break processing (GO:0000729)3.23253243
61genitalia morphogenesis (GO:0035112)3.22351126
62chaperone-mediated protein complex assembly (GO:0051131)3.18876203
63RNA destabilization (GO:0050779)3.17846024
64positive regulation of guanylate cyclase activity (GO:0031284)3.12552474
65axoneme assembly (GO:0035082)3.10452158
66retinal cone cell development (GO:0046549)3.09141204
67multicellular organismal development (GO:0007275)3.08171113
68regulation of meiosis I (GO:0060631)3.07793318
69coenzyme catabolic process (GO:0009109)2.98242220
70synapsis (GO:0007129)2.98057257
71carnitine transport (GO:0015879)2.95452927
72amino-acid betaine transport (GO:0015838)2.95452927
73chromosome condensation (GO:0030261)2.94133647
74cilium organization (GO:0044782)2.93586820
75indolalkylamine metabolic process (GO:0006586)2.92522461
76cellular component assembly involved in morphogenesis (GO:0010927)2.88241810
77left/right pattern formation (GO:0060972)2.88040247
78microtubule polymerization or depolymerization (GO:0031109)2.87896955
79carnitine transmembrane transport (GO:1902603)2.86225888
80meiosis I (GO:0007127)2.84833903
81seminiferous tubule development (GO:0072520)2.84701989
82C4-dicarboxylate transport (GO:0015740)2.84312734
83intraciliary transport (GO:0042073)2.83713813
84cilium assembly (GO:0042384)2.82685854
85microtubule-based movement (GO:0007018)2.81576456
86peptidyl-lysine dimethylation (GO:0018027)2.81561484
87proline transport (GO:0015824)2.80882255
88transmission of nerve impulse (GO:0019226)2.80499132
89regulation of guanylate cyclase activity (GO:0031282)2.79428300
90negative regulation of cytosolic calcium ion concentration (GO:0051481)2.78259881
91behavioral response to nicotine (GO:0035095)2.77961586
92limb bud formation (GO:0060174)2.77778090
93arginine catabolic process (GO:0006527)2.75700541
94G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.74944964
95cornea development in camera-type eye (GO:0061303)2.72308067
96nucleus organization (GO:0006997)2.71962686
97regulation of centriole replication (GO:0046599)2.71441837
98protein localization to cilium (GO:0061512)2.70251388
99calcium ion import (GO:0070509)2.69906984
100nonmotile primary cilium assembly (GO:0035058)2.67057931
101DNA packaging (GO:0006323)2.64332624
102regulation of acrosome reaction (GO:0060046)2.61947860
103glycolytic process (GO:0006096)2.61591234
104regulation of rhodopsin mediated signaling pathway (GO:0022400)2.61317815
105rhodopsin mediated signaling pathway (GO:0016056)2.60623974
106dopamine transport (GO:0015872)2.59166618
107double-strand break repair via homologous recombination (GO:0000724)2.57773584
108behavioral response to ethanol (GO:0048149)2.57326772
109negative regulation of cAMP-mediated signaling (GO:0043951)2.57176532
110recombinational repair (GO:0000725)2.57074809
111tryptophan catabolic process (GO:0006569)2.55704606
112indole-containing compound catabolic process (GO:0042436)2.55704606
113indolalkylamine catabolic process (GO:0046218)2.55704606
114detection of chemical stimulus involved in sensory perception of smell (GO:0050911)2.55702828
115microtubule nucleation (GO:0007020)2.55466865
116single-organism membrane fusion (GO:0044801)2.52788957
117brain morphogenesis (GO:0048854)2.52061698
118peptidyl-threonine dephosphorylation (GO:0035970)2.51656995
119regulation of spindle checkpoint (GO:0090231)2.51496949
120cilium morphogenesis (GO:0060271)2.50215087
121polyol catabolic process (GO:0046174)2.49960820
122regulation of cytokine production involved in inflammatory response (GO:1900015)2.48480705
123lactate metabolic process (GO:0006089)2.47308281
124meiotic cell cycle process (GO:1903046)2.46370586
125alditol metabolic process (GO:0019400)2.42461728
126negative regulation of organelle assembly (GO:1902116)2.41279980
127macroautophagy (GO:0016236)2.39935344
128peptidyl-glutamic acid modification (GO:0018200)2.39179732
129membrane depolarization during action potential (GO:0086010)2.36180821
130meiotic cell cycle (GO:0051321)2.33998688
131protein refolding (GO:0042026)2.33421434
132histone H3-K9 methylation (GO:0051567)2.30197206
133histone exchange (GO:0043486)2.28169146
134nucleoside diphosphate phosphorylation (GO:0006165)2.26728104
135positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.26659387
136cell wall macromolecule catabolic process (GO:0016998)18.4813093
137cell wall macromolecule metabolic process (GO:0044036)18.4813093
138fusion of sperm to egg plasma membrane (GO:0007342)15.1697337
139acrosome assembly (GO:0001675)13.8053131
140multicellular organism reproduction (GO:0032504)13.5619431
141sperm-egg recognition (GO:0035036)12.4831163
142sperm motility (GO:0030317)12.1244810
143plasma membrane fusion (GO:0045026)11.6040554
144reproduction (GO:0000003)11.5825434
145cilium or flagellum-dependent cell motility (GO:0001539)11.4964026
146cell-cell recognition (GO:0009988)11.2326580
147binding of sperm to zona pellucida (GO:0007339)10.3922678
148acrosome reaction (GO:0007340)10.1281233

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.32815455
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse5.36284705
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.08796262
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.34421654
5GBX2_23144817_ChIP-Seq_PC3_Human3.21624486
6CBX2_27304074_Chip-Seq_ESCs_Mouse2.86047883
7ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.80571294
8FLI1_27457419_Chip-Seq_LIVER_Mouse2.79476374
9PCGF2_27294783_Chip-Seq_ESCs_Mouse2.75805250
10FUS_26573619_Chip-Seq_HEK293_Human2.62490622
11PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.57567073
12KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse2.37279362
13ZFP57_27257070_Chip-Seq_ESCs_Mouse2.34185940
14KAP1_22055183_ChIP-Seq_ESCs_Mouse2.32818833
15* CTBP1_25329375_ChIP-Seq_LNCAP_Human2.31272801
16RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse2.28016765
17POU3F2_20337985_ChIP-ChIP_501MEL_Human2.27330571
18ZNF652_21678463_ChIP-ChIP_ZR75-1_Human2.26424288
19P300_19829295_ChIP-Seq_ESCs_Human2.24513398
20EZH2_22144423_ChIP-Seq_EOC_Human2.13099526
21PCGF2_27294783_Chip-Seq_NPCs_Mouse2.11152776
22TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse2.08037583
23GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.05738730
24* ER_23166858_ChIP-Seq_MCF-7_Human1.95694937
25VDR_22108803_ChIP-Seq_LS180_Human1.94630007
26KDM2B_26808549_Chip-Seq_REH_Human1.92887243
27CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.90072523
28AR_25329375_ChIP-Seq_VCAP_Human1.88195637
29SMAD4_21799915_ChIP-Seq_A2780_Human1.88049218
30IGF1R_20145208_ChIP-Seq_DFB_Human1.87495452
31ZNF274_21170338_ChIP-Seq_K562_Hela1.86014974
32TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.83827662
33CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.83748327
34SUZ12_27294783_Chip-Seq_NPCs_Mouse1.83434262
35GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.83247383
36NFE2_27457419_Chip-Seq_LIVER_Mouse1.80684383
37EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.80463394
38* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.79987459
39SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.78649703
40TAL1_26923725_Chip-Seq_HPCs_Mouse1.78097866
41* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.76993349
42STAT6_21828071_ChIP-Seq_BEAS2B_Human1.75938413
43FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.73881477
44EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.69558656
45SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.69517185
46CMYC_18555785_Chip-Seq_ESCs_Mouse1.69329365
47OCT4_18555785_Chip-Seq_ESCs_Mouse1.67044778
48NANOG_18555785_Chip-Seq_ESCs_Mouse1.66520698
49* STAT3_23295773_ChIP-Seq_U87_Human1.65831801
50FLI1_21867929_ChIP-Seq_TH2_Mouse1.64317603
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.59431015
52CRX_20693478_ChIP-Seq_RETINA_Mouse1.59052689
53P300_18555785_Chip-Seq_ESCs_Mouse1.58980307
54NR3C1_21868756_ChIP-Seq_MCF10A_Human1.58222498
55EWS_26573619_Chip-Seq_HEK293_Human1.55302345
56P53_22387025_ChIP-Seq_ESCs_Mouse1.55276785
57SMAD4_21741376_ChIP-Seq_EPCs_Human1.54226623
58PIAS1_25552417_ChIP-Seq_VCAP_Human1.54141724
59SUZ12_18555785_Chip-Seq_ESCs_Mouse1.52805925
60KLF4_18555785_Chip-Seq_ESCs_Mouse1.52291655
61EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.52189869
62NANOG_19829295_ChIP-Seq_ESCs_Human1.51730602
63SOX2_19829295_ChIP-Seq_ESCs_Human1.51730602
64* STAT1_17558387_ChIP-Seq_HELA_Human1.51402047
65* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.50989269
66ESRRB_18555785_Chip-Seq_ESCs_Mouse1.50978819
67KLF5_20875108_ChIP-Seq_MESCs_Mouse1.50869191
68EZH2_27294783_Chip-Seq_NPCs_Mouse1.50264770
69GATA1_26923725_Chip-Seq_HPCs_Mouse1.49944760
70MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.48018833
71* TCF4_23295773_ChIP-Seq_U87_Human1.47963414
72PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.47603889
73TOP2B_26459242_ChIP-Seq_MCF-7_Human1.46998861
74ELK4_26923725_Chip-Seq_MESODERM_Mouse1.46413517
75RNF2_27304074_Chip-Seq_NSC_Mouse1.46410380
76GATA3_21867929_ChIP-Seq_CD8_Mouse1.46116396
77BCAT_22108803_ChIP-Seq_LS180_Human1.44950938
78CTCF_18555785_Chip-Seq_ESCs_Mouse1.44384388
79SOX2_18555785_Chip-Seq_ESCs_Mouse1.43428444
80GATA3_21867929_ChIP-Seq_TH1_Mouse1.42924594
81STAT3_18555785_Chip-Seq_ESCs_Mouse1.42724400
82RUNX2_22187159_ChIP-Seq_PCA_Human1.42184353
83RUNX1_27457419_Chip-Seq_LIVER_Mouse1.38659472
84TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38021995
85LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.37878321
86CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.37829491
87WDR5_24793694_ChIP-Seq_LNCAP_Human1.37380540
88MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.36422149
89OCT4_21477851_ChIP-Seq_ESCs_Mouse1.34792255
90AR_21572438_ChIP-Seq_LNCaP_Human1.34339290
91* TCF4_22108803_ChIP-Seq_LS180_Human1.33968422
92SMAD1_18555785_Chip-Seq_ESCs_Mouse1.33593860
93NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.33224152
94E2F1_18555785_Chip-Seq_ESCs_Mouse1.32507184
95* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.31134501
96* CBP_20019798_ChIP-Seq_JUKART_Human1.31134501
97NMYC_18555785_Chip-Seq_ESCs_Mouse1.26481086
98MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.25158769
99CDX2_22108803_ChIP-Seq_LS180_Human1.24928092
100MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.24525550
101DROSHA_22980978_ChIP-Seq_HELA_Human1.24482717
102* AUTS2_25519132_ChIP-Seq_293T-REX_Human1.24084820
103FOXA1_21572438_ChIP-Seq_LNCaP_Human1.23171230
104GF1_26923725_Chip-Seq_HPCs_Mouse1.22514933
105TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.21731636
106PU1_27457419_Chip-Seq_LIVER_Mouse1.21428699
107SOX2_22085726_ChIP-Seq_NPCs_Mouse1.21232668
108FOXA1_27270436_Chip-Seq_PROSTATE_Human1.20549851
109FOXA1_25329375_ChIP-Seq_VCAP_Human1.20549851
110PRDM14_20953172_ChIP-Seq_ESCs_Human1.20415004
111* FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.19779382
112TP53_22573176_ChIP-Seq_HFKS_Human1.19712037
113ZFX_18555785_Chip-Seq_ESCs_Mouse1.18453594
114KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.18258791
115REST_21632747_ChIP-Seq_MESCs_Mouse1.15540449
116PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.14822586
117GATA3_21878914_ChIP-Seq_MCF-7_Human1.14383207
118MYC_19829295_ChIP-Seq_ESCs_Human1.13464262
119* ETV2_25802403_ChIP-Seq_MESCs_Mouse1.12378485
120ARNT_22903824_ChIP-Seq_MCF-7_Human1.11536685
121SMAD3_21741376_ChIP-Seq_ESCs_Human1.11349588
122SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.11324663
123TAF15_26573619_Chip-Seq_HEK293_Human1.11312345
124GF1B_26923725_Chip-Seq_HPCs_Mouse1.11092990
125NCOR_22424771_ChIP-Seq_293T_Human1.10950531
126SOX9_26525672_Chip-Seq_HEART_Mouse1.09023999
127CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.08803093
128* RUNX1_26923725_Chip-Seq_HPCs_Mouse1.08292167
129OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08177724
130SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.06646813
131TP53_18474530_ChIP-ChIP_U2OS_Human1.06407734
132SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.05581316
133NFYB_21822215_ChIP-Seq_K562_Human1.04629833
134SOX2_21211035_ChIP-Seq_LN229_Gbm1.04595954
135PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.03954769
136HOXB7_26014856_ChIP-Seq_BT474_Human1.03880627
137NANOG_20526341_ChIP-Seq_ESCs_Human1.02898157
138TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02889273
139POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.02889273
140* GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.02838828
141ESET_19884257_ChIP-Seq_ESCs_Mouse1.02681793
142TBL1_22424771_ChIP-Seq_293T_Human1.02594481
143ETV1_20927104_ChIP-Seq_GIST48_Human1.01798915
144PHF8_20622853_ChIP-Seq_HELA_Human1.01540997
145EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.00503356
146P53_21459846_ChIP-Seq_SAOS-2_Human0.99943683
147EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.99523962
148* SPI1_26923725_Chip-Seq_HPCs_Mouse0.99055967
149E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.99019016
150SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.98252284
151HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.97489932
152CDX2_19796622_ChIP-Seq_MESCs_Mouse0.96764697
153NFIB_24661679_ChIP-Seq_LUNG_Mouse0.92935241
154STAT3_18555785_ChIP-Seq_MESCs_Mouse0.91468720
155LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.91361797
156CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.89753936
157SALL1_21062744_ChIP-ChIP_HESCs_Human0.87747120
158RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.87508227
159UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.87359353
160EP300_21415370_ChIP-Seq_HL-1_Mouse0.87253192
161GATA1_19941827_ChIP-Seq_MEL86_Mouse0.85557541

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive6.13177542
2MP0001929_abnormal_gametogenesis5.51517089
3MP0008877_abnormal_DNA_methylation4.55634264
4MP0002653_abnormal_ependyma_morphology4.01336189
5MP0002210_abnormal_sex_determination3.54625942
6MP0002161_abnormal_fertility/fecundity3.28779185
7MP0001145_abnormal_male_reproductive3.07168481
8MP0005623_abnormal_meninges_morphology2.95240001
9MP0000653_abnormal_sex_gland2.71168715
10MP0009046_muscle_twitch2.52059318
11MP0001486_abnormal_startle_reflex2.18994500
12MP0000372_irregular_coat_pigmentation2.01729694
13MP0003880_abnormal_central_pattern2.01352839
14MP0005410_abnormal_fertilization15.3618758
15MP0002138_abnormal_hepatobiliary_system1.85427954
16MP0005670_abnormal_white_adipose1.83695167
17MP0005646_abnormal_pituitary_gland1.82959008
18MP0003195_calcinosis1.80601590
19MP0008058_abnormal_DNA_repair1.77688740
20MP0004233_abnormal_muscle_weight1.75561803
21MP0001501_abnormal_sleep_pattern1.75390974
22MP0003718_maternal_effect1.72660125
23MP0001485_abnormal_pinna_reflex1.67609239
24MP0006276_abnormal_autonomic_nervous1.65205944
25MP0002282_abnormal_trachea_morphology1.61902395
26MP0009780_abnormal_chondrocyte_physiolo1.57752596
27MP0002272_abnormal_nervous_system1.52819585
28MP0006292_abnormal_olfactory_placode1.46422270
29MP0005645_abnormal_hypothalamus_physiol1.45692434
30MP0004742_abnormal_vestibular_system1.45225955
31MP0002876_abnormal_thyroid_physiology1.42864856
32MP0000516_abnormal_urinary_system1.30912015
33MP0005367_renal/urinary_system_phenotyp1.30912015
34MP0003787_abnormal_imprinting1.29336279
35MP0001765_abnormal_ion_homeostasis1.26184327
36MP0002735_abnormal_chemical_nociception1.25383902
37MP0005379_endocrine/exocrine_gland_phen1.23254437
38MP0001984_abnormal_olfaction1.23127487
39MP0002557_abnormal_social/conspecific_i1.20812556
40MP0002102_abnormal_ear_morphology1.16148305
41MP0002733_abnormal_thermal_nociception1.14729871
42MP0000631_abnormal_neuroendocrine_gland1.12609552
43MP0003136_yellow_coat_color1.12020512
44MP0005084_abnormal_gallbladder_morpholo1.11462939
45MP0005310_abnormal_salivary_gland1.10658790
46MP0002067_abnormal_sensory_capabilities1.10389867
47MP0004085_abnormal_heartbeat1.09448342
48MP0001970_abnormal_pain_threshold1.09377894
49MP0001963_abnormal_hearing_physiology1.08623985
50MP0000569_abnormal_digit_pigmentation1.08256579
51MP0001986_abnormal_taste_sensitivity1.07514235
52MP0006072_abnormal_retinal_apoptosis1.07118036
53MP0004215_abnormal_myocardial_fiber1.01499027
54MP0005647_abnormal_sex_gland0.99446035
55MP0005395_other_phenotype0.98996854
56MP0004859_abnormal_synaptic_plasticity0.98261187
57MP0001905_abnormal_dopamine_level0.97811281
58MP0003646_muscle_fatigue0.95144967
59MP0000026_abnormal_inner_ear0.94860319
60MP0002063_abnormal_learning/memory/cond0.93202462
61MP0002734_abnormal_mechanical_nocicepti0.92064982
62MP0002160_abnormal_reproductive_system0.90540458
63MP0001348_abnormal_lacrimal_gland0.89992799
64MP0003283_abnormal_digestive_organ0.89471142
65MP0008789_abnormal_olfactory_epithelium0.88201180
66MP0000778_abnormal_nervous_system0.87846942
67MP0000230_abnormal_systemic_arterial0.87736728
68MP0003183_abnormal_peptide_metabolism0.87703366
69MP0008995_early_reproductive_senescence0.85297203
70MP0002928_abnormal_bile_duct0.84759105
71MP0000678_abnormal_parathyroid_gland0.81628158
72MP0002254_reproductive_system_inflammat0.81535622
73MP0002234_abnormal_pharynx_morphology0.81306218
74MP0003137_abnormal_impulse_conducting0.81075666
75MP0001529_abnormal_vocalization0.79400095
76MP0004043_abnormal_pH_regulation0.77632470
77MP0008057_abnormal_DNA_replication0.77338094
78MP0000383_abnormal_hair_follicle0.76232220
79MP0005171_absent_coat_pigmentation0.75997050
80MP0000015_abnormal_ear_pigmentation0.75965988
81MP0005423_abnormal_somatic_nervous0.75892922
82MP0005386_behavior/neurological_phenoty0.75634646
83MP0004924_abnormal_behavior0.75634646
84MP0002837_dystrophic_cardiac_calcinosis0.70546688
85MP0010094_abnormal_chromosome_stability0.67493349
86MP0003633_abnormal_nervous_system0.67379351
87MP0004036_abnormal_muscle_relaxation0.65634060
88MP0004084_abnormal_cardiac_muscle0.65275057
89MP0005636_abnormal_mineral_homeostasis0.64621383
90MP0003950_abnormal_plasma_membrane0.63027923
91MP0002139_abnormal_hepatobiliary_system0.62303267
92MP0003699_abnormal_female_reproductive0.58220450
93MP0004019_abnormal_vitamin_homeostasis0.55891260
94MP0009697_abnormal_copulation0.54961250
95MP0005551_abnormal_eye_electrophysiolog0.54362549
96MP0002132_abnormal_respiratory_system0.54082211
97MP0008875_abnormal_xenobiotic_pharmacok0.51735747
98MP0001324_abnormal_eye_pigmentation0.50397796
99MP0005389_reproductive_system_phenotype0.50320743
100MP0001119_abnormal_female_reproductive0.49990015
101MP0001293_anophthalmia0.47489552
102MP0004133_heterotaxia0.46496726
103MP0002269_muscular_atrophy0.44391301
104MP0010307_abnormal_tumor_latency0.44120761
105MP0003631_nervous_system_phenotype0.43001028
106MP0005365_abnormal_bile_salt0.40407056
107MP0002971_abnormal_brown_adipose0.39948108
108MP0000427_abnormal_hair_cycle0.39565839
109MP0005253_abnormal_eye_physiology0.37887041
110MP0004145_abnormal_muscle_electrophysio0.35968791
111MP0006036_abnormal_mitochondrial_physio0.35362875
112MP0003011_delayed_dark_adaptation0.35341191
113MP0001764_abnormal_homeostasis0.34968690
114MP0008872_abnormal_physiological_respon0.34914231
115MP0002736_abnormal_nociception_after0.31115380
116MP0000358_abnormal_cell_content/0.30862808
117MP0005319_abnormal_enzyme/_coenzyme0.30855835
118MP0005360_urolithiasis0.28526202
119MP0004811_abnormal_neuron_physiology0.28182918
120MP0001968_abnormal_touch/_nociception0.26961585
121MP0003115_abnormal_respiratory_system0.26890599
122MP0002133_abnormal_respiratory_system0.26643258
123MP0005388_respiratory_system_phenotype0.26643258
124MP0002572_abnormal_emotion/affect_behav0.26126651
125MP0009115_abnormal_fat_cell0.25694518
126MP0002152_abnormal_brain_morphology0.25657914
127MP0000432_abnormal_head_morphology0.23183100
128MP0004130_abnormal_muscle_cell0.23090768
129MP0005391_vision/eye_phenotype0.23069340
130MP0003861_abnormal_nervous_system0.23019434
131MP0005535_abnormal_body_temperature0.22872125
132MP0002163_abnormal_gland_morphology0.21625010
133MP0000647_abnormal_sebaceous_gland0.21240380
134MP0009745_abnormal_behavioral_response0.21179454
135MP0002229_neurodegeneration0.21155825
136MP0002064_seizures0.21063476
137MP0005195_abnormal_posterior_eye0.20618060
138MP0003329_amyloid_beta_deposits0.20555572
139MP0009250_abnormal_appendicular_skeleto0.20534786
140MP0000313_abnormal_cell_death0.20141732
141MP0002009_preneoplasia0.19500543
142MP0003635_abnormal_synaptic_transmissio0.18554607
143MP0002118_abnormal_lipid_homeostasis0.17804229
144MP0002405_respiratory_system_inflammati0.17143727
145MP0006035_abnormal_mitochondrial_morpho0.16105705
146MP0002084_abnormal_developmental_patter0.15549213
147MP0002693_abnormal_pancreas_physiology0.15443002
148MP0002752_abnormal_somatic_nervous0.15218128
149MP0003705_abnormal_hypodermis_morpholog0.15030926
150MP0008569_lethality_at_weaning0.14524979
151MP0005409_darkened_coat_color0.14236555
152MP0001730_embryonic_growth_arrest0.14210115
153MP0005666_abnormal_adipose_tissue0.14196139
154MP0003943_abnormal_hepatobiliary_system0.13721082
155MP0002169_no_abnormal_phenotype0.13674370
156MP0005085_abnormal_gallbladder_physiolo0.13621203
157MP0002873_normal_phenotype0.13507764
158MP0003878_abnormal_ear_physiology0.13468012
159MP0005377_hearing/vestibular/ear_phenot0.13468012

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.43068387
2Abnormal respiratory motile cilium morphology (HP:0005938)8.46113567
3Abnormal respiratory epithelium morphology (HP:0012253)8.46113567
4Abnormal ciliary motility (HP:0012262)8.16036157
5Rhinitis (HP:0012384)7.61406227
6Chronic bronchitis (HP:0004469)7.12444241
7Nasal polyposis (HP:0100582)6.32766873
8Severe visual impairment (HP:0001141)5.50799986
9Infertility (HP:0000789)5.28515792
10Abnormality of the nasal mucosa (HP:0000433)5.21215480
11Bronchitis (HP:0012387)4.61427096
12Attenuation of retinal blood vessels (HP:0007843)4.51828315
13Bronchiectasis (HP:0002110)4.49625192
14Abnormal rod and cone electroretinograms (HP:0008323)4.26944566
15Tongue fasciculations (HP:0001308)4.20031313
16Male infertility (HP:0003251)3.99058597
17Bony spicule pigmentary retinopathy (HP:0007737)3.96742990
18Abnormality of macular pigmentation (HP:0008002)3.95661392
19Muscle fibrillation (HP:0010546)3.86867306
20Nephronophthisis (HP:0000090)3.85551810
21Medial flaring of the eyebrow (HP:0010747)3.83051074
22Recurrent sinusitis (HP:0011108)3.80658636
23Abnormal spermatogenesis (HP:0008669)3.62287240
24Congenital stationary night blindness (HP:0007642)3.49139534
25Recurrent otitis media (HP:0000403)3.25785786
26Abnormality of midbrain morphology (HP:0002418)3.02705872
27Molar tooth sign on MRI (HP:0002419)3.02705872
28Pendular nystagmus (HP:0012043)3.00334169
29Recurrent bronchitis (HP:0002837)2.94082334
30Abnormality of the renal medulla (HP:0100957)2.88928104
31Progressive cerebellar ataxia (HP:0002073)2.82503036
32Gait imbalance (HP:0002141)2.81241749
33Azoospermia (HP:0000027)2.80982769
34Congenital primary aphakia (HP:0007707)2.79347883
35Absent rod-and cone-mediated responses on ERG (HP:0007688)2.71181149
36Congenital sensorineural hearing impairment (HP:0008527)2.70108009
37Abnormality of the labia minora (HP:0012880)2.61681104
38Type II lissencephaly (HP:0007260)2.60136668
39Abnormality of saccadic eye movements (HP:0000570)2.56441845
40Tubulointerstitial nephritis (HP:0001970)2.52666248
41Generalized aminoaciduria (HP:0002909)2.51260751
42Gaze-evoked nystagmus (HP:0000640)2.51146562
43Tubular atrophy (HP:0000092)2.49198836
44Chronic sinusitis (HP:0011109)2.43297235
45Pancreatic fibrosis (HP:0100732)2.41808008
46Slow saccadic eye movements (HP:0000514)2.40601698
47Hyperventilation (HP:0002883)2.39090251
48Nephrogenic diabetes insipidus (HP:0009806)2.38930775
49Febrile seizures (HP:0002373)2.31119071
50Intestinal atresia (HP:0011100)2.29926863
51Focal seizures (HP:0007359)2.29190097
52Impaired smooth pursuit (HP:0007772)2.27827186
53Increased corneal curvature (HP:0100692)2.27695670
54Keratoconus (HP:0000563)2.27695670
55Polyuria (HP:0000103)2.26959102
56Tubulointerstitial abnormality (HP:0001969)2.23263428
57Genital tract atresia (HP:0001827)2.22859595
58Microglossia (HP:0000171)2.20515509
59Abolished electroretinogram (ERG) (HP:0000550)2.15542061
60Volvulus (HP:0002580)2.13193856
61Sclerocornea (HP:0000647)2.10107295
62Poor coordination (HP:0002370)2.08983380
63Vaginal atresia (HP:0000148)2.07775591
64Hyperkalemia (HP:0002153)2.07310594
65Small hand (HP:0200055)2.03568244
66Congenital hepatic fibrosis (HP:0002612)2.03141098
67Aplasia/Hypoplasia of the fovea (HP:0008060)2.01454500
68Hypoplasia of the fovea (HP:0007750)2.01454500
69Renal cortical cysts (HP:0000803)2.00808048
70Glycosuria (HP:0003076)2.00627009
71Abnormality of urine glucose concentration (HP:0011016)2.00627009
72Abnormality of ocular smooth pursuit (HP:0000617)2.00316586
73Respiratory insufficiency due to defective ciliary clearance (HP:0200073)14.0322130
74Dynein arm defect of respiratory motile cilia (HP:0012255)12.0792449
75Absent/shortened dynein arms (HP:0200106)12.0792449
76Postaxial foot polydactyly (HP:0001830)1.99144610
77Aplasia/Hypoplasia of the uvula (HP:0010293)1.98887081
78Abnormality of dental color (HP:0011073)1.98618934
79Anencephaly (HP:0002323)1.96931987
80Amelogenesis imperfecta (HP:0000705)1.91171689
81Focal motor seizures (HP:0011153)1.91050035
82Hypoplastic ischia (HP:0003175)1.91022089
83Photophobia (HP:0000613)1.90437969
84Chronic hepatic failure (HP:0100626)1.89521264
85Aplasia/Hypoplasia of the tongue (HP:0010295)1.89097243
86Sloping forehead (HP:0000340)1.87698074
87Absent speech (HP:0001344)1.85457678
88Inability to walk (HP:0002540)1.84490703
89Facial cleft (HP:0002006)1.84476591
90Tubulointerstitial fibrosis (HP:0005576)1.84291613
91Astigmatism (HP:0000483)1.83469809
92Decreased central vision (HP:0007663)1.82164053
93Postaxial hand polydactyly (HP:0001162)1.82113717
94Lissencephaly (HP:0001339)1.81576177
95Aplasia/Hypoplasia of the lens (HP:0008063)1.81540232
96Retinal dysplasia (HP:0007973)1.78682871
97Abnormality of the ileum (HP:0001549)1.78377930
98Gastrointestinal atresia (HP:0002589)1.77307168
99Aplasia/Hypoplasia of the earlobes (HP:0009906)1.77159936
100Hyperglycinemia (HP:0002154)1.76931562
101Limb ataxia (HP:0002070)1.75998098
102Median cleft lip (HP:0000161)1.75382035
103Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.74737759
104Atonic seizures (HP:0010819)1.73869161
105Amblyopia (HP:0000646)1.73494957
106Abnormality of the fovea (HP:0000493)1.72859183
107Hypoplastic iliac wings (HP:0002866)1.71519550
108Abnormal drinking behavior (HP:0030082)1.70417897
109Polydipsia (HP:0001959)1.70417897
110Asymmetric septal hypertrophy (HP:0001670)1.70221286
111Type II diabetes mellitus (HP:0005978)1.67394330
112Potter facies (HP:0002009)1.66761079
113Facial shape deformation (HP:0011334)1.66761079
114Ketosis (HP:0001946)1.66544782
115Hemiparesis (HP:0001269)1.66170394
116Bile duct proliferation (HP:0001408)1.64236987
117Abnormal biliary tract physiology (HP:0012439)1.64236987
118Impulsivity (HP:0100710)1.64168491
119Spontaneous abortion (HP:0005268)1.61626027
120Stage 5 chronic kidney disease (HP:0003774)1.59217643
121Abnormality of the renal cortex (HP:0011035)1.59118405
122Absent frontal sinuses (HP:0002688)1.58820623
123Short ribs (HP:0000773)1.58697188
124Abnormality of renal excretion (HP:0011036)1.58551004
125Cystic liver disease (HP:0006706)1.55025090
126True hermaphroditism (HP:0010459)1.52183090
127Renal dysplasia (HP:0000110)1.51441224
128Fibular hypoplasia (HP:0003038)1.51377863
129Oculomotor apraxia (HP:0000657)1.49546880
130Abnormality of the dental root (HP:0006486)1.47271796
131Taurodontia (HP:0000679)1.47271796
132Abnormality of permanent molar morphology (HP:0011071)1.47271796
133Pancreatic cysts (HP:0001737)1.46297051
134Papillary thyroid carcinoma (HP:0002895)1.45721703
135J-shaped sella turcica (HP:0002680)1.44785754
136Chronic otitis media (HP:0000389)1.44029736
137Abnormality of molar morphology (HP:0011070)1.40700851
138Abnormality of molar (HP:0011077)1.40700851
139Bundle branch block (HP:0011710)1.39225153
140Abnormality of the dental pulp (HP:0006479)1.33783263
141Vascular calcification (HP:0004934)1.32785281
142Heterotopia (HP:0002282)1.31826749
143Dyschromatopsia (HP:0007641)1.31647739
144Abnormality of lateral ventricle (HP:0030047)1.30459368
145Broad foot (HP:0001769)1.28650706
146Cone-rod dystrophy (HP:0000548)1.27658818
147Supernumerary spleens (HP:0009799)1.27047304
148Renovascular hypertension (HP:0100817)1.26912972
149Constricted visual fields (HP:0001133)1.26755234
150Cerebellar dysplasia (HP:0007033)1.26703562
151Occipital encephalocele (HP:0002085)1.25819800
152Dental crowding (HP:0000678)1.25767382
153Cardiovascular calcification (HP:0011915)1.21165772
154Nephroblastoma (Wilms tumor) (HP:0002667)1.20224607
155Abnormal gallbladder physiology (HP:0012438)1.19084211
156Cholecystitis (HP:0001082)1.19084211
157Abnormality of the lower motor neuron (HP:0002366)1.18337514
158Abnormal urine output (HP:0012590)1.16388297

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK39.86469966
2PDK49.86469966
3PDK26.42830481
4FRK6.06923459
5MAP4K24.24735588
6INSRR3.27052178
7TESK12.97348218
8WNK32.47409241
9PRKD32.42847097
10PLK22.42005052
11ADRBK22.27826058
12PTK2B2.20401717
13BMPR1B2.14099905
14STK392.11381326
15WNK42.07873184
16ICK2.06800375
17CASK1.84970964
18NUAK11.80237636
19LMTK21.65049704
20MAPK131.64482476
21NTRK31.57891720
22ZAK1.57365117
23TAOK31.45991964
24GRK11.40308119
25EPHA41.26203840
26TRIM281.24734833
27FGFR21.20458424
28STK381.19411059
29PDK11.16795175
30BRSK21.13228598
31PAK31.06770422
32BRD41.04944545
33PNCK1.02711745
34PLK40.95439011
35MAP2K70.95408201
36BCKDK0.95067156
37WEE10.94848471
38STK38L0.93887619
39PRKCE0.93118737
40MKNK20.91701739
41TNIK0.89593366
42DDR20.84236203
43IRAK10.83279798
44NEK20.82419731
45DAPK20.81786054
46EIF2AK30.79101881
47CSNK1G30.78408897
48DYRK20.78306547
49CSNK1G20.78294128
50FER0.77582598
51ERBB30.75004670
52CHEK20.73505151
53TYRO30.71023401
54CSNK1G10.68765481
55BUB10.63222886
56DYRK1B0.62786882
57CSNK1A1L0.61709641
58CCNB10.60511664
59CDK120.57441302
60PIK3CG0.56792384
61WNK10.56696824
62MAP2K60.54744442
63BCR0.54614586
64PLK30.53750550
65CAMK10.53575486
66PDPK10.53384854
67ZAP700.50785799
68RIPK40.49605726
69ADRBK10.49101944
70NEK10.47376206
71ROCK10.46830045
72TTK0.46689319
73CAMK1D0.46667578
74BRSK10.45882410
75MAP3K40.45364706
76STK30.45314778
77DYRK30.43880610
78MST40.43175816
79RIPK10.43161968
80CDK190.42616112
81CHEK10.42585789
82PASK0.38277044
83CSNK1A10.38245191
84GRK50.38233992
85IRAK20.34675362
86TXK0.34142596
87PRKACA0.33991019
88PRKAA20.33905866
89TGFBR10.33680578
90CDK30.33259158
91MET0.32981687
92TNK20.32739568
93SGK20.32719610
94PDGFRB0.31825430
95TIE10.31323528
96NEK60.31053763
97MKNK10.30429491
98MARK30.29913709
99PKN10.29277543
100PRKCI0.29013110
101CAMK40.28876087
102UHMK10.28809473
103CSNK1D0.28681680
104PHKG20.28604746
105PHKG10.28604746
106KDR0.28396971
107PRKG20.28148580
108PRKCG0.27758588
109YES10.27250439
110ATM0.23555404
111OXSR10.22880573
112PAK10.22099716
113MAPK150.21765184
114PLK10.20554092
115ATR0.20254501
116MUSK0.19816769
117CDC70.19764052
118TESK20.18541537
119EEF2K0.18264714
120CSNK2A20.15349886
121PRKCQ0.14346458
122MAP2K40.13282660
123STK100.12800589
124CAMK1G0.12411890
125PRKG10.11684339
126AKT30.11465761
127PRKCZ0.11411349
128MAPKAPK50.09984061
129MINK10.09463333
130EGFR0.09092713
131RPS6KB10.08928868
132CSNK2A10.08478447
133PRKAA10.08455724
134ACVR1B0.08203402
135CDK150.08177555
136STK110.07993753
137GSK3A0.07836693
138CAMK2A0.07405601
139NTRK20.07395915
140MAPK100.07339355
141PRKACG0.07338636
142PINK10.06417152
143MARK10.06173888
144GSK3B0.05972618
145TTN0.05853919
146CDK180.05530115
147CDK20.05068153
148CDK10.04942729
149PAK20.04810052
150MAPK80.04490659
151PRKCD0.04222875
152CDK11A0.04027456
153MAP3K50.03540180
154PRKDC0.03443956
155CDK50.03262904
156MTOR0.03036777
157CDK140.02775101
158PRKCA0.02763312
159CAMKK10.02207492
160PRKCB0.01650736
161LATS10.00999091
162CDK60.00524235
163AURKA0.00309712

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000725.02855984
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.13262769
3Pentose phosphate pathway_Homo sapiens_hsa000303.84204763
4Vitamin B6 metabolism_Homo sapiens_hsa007503.65972301
5Pyruvate metabolism_Homo sapiens_hsa006203.65672330
6Phototransduction_Homo sapiens_hsa047443.32062967
7Butanoate metabolism_Homo sapiens_hsa006503.28281627
8Propanoate metabolism_Homo sapiens_hsa006403.10276275
9Glycosaminoglycan degradation_Homo sapiens_hsa005313.09876567
10Fatty acid biosynthesis_Homo sapiens_hsa000613.04598591
11Basal transcription factors_Homo sapiens_hsa030222.97445412
12Renin-angiotensin system_Homo sapiens_hsa046142.40418192
13Glucagon signaling pathway_Homo sapiens_hsa049222.39196896
14Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.35947995
15Nicotine addiction_Homo sapiens_hsa050332.28021690
16alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.24495884
17Linoleic acid metabolism_Homo sapiens_hsa005912.22524778
18Oocyte meiosis_Homo sapiens_hsa041142.02864734
19Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.99078840
20Carbon metabolism_Homo sapiens_hsa012001.97167729
21Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.87120810
22Glycerolipid metabolism_Homo sapiens_hsa005611.86999847
23Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.86883699
24Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.82882241
25Tryptophan metabolism_Homo sapiens_hsa003801.79658590
26Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.77933226
27Biosynthesis of amino acids_Homo sapiens_hsa012301.71159674
28Selenocompound metabolism_Homo sapiens_hsa004501.68964184
29Fanconi anemia pathway_Homo sapiens_hsa034601.65199667
30Carbohydrate digestion and absorption_Homo sapiens_hsa049731.60451631
31Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.59425642
32PPAR signaling pathway_Homo sapiens_hsa033201.58523671
33Mineral absorption_Homo sapiens_hsa049781.56680696
34Protein export_Homo sapiens_hsa030601.56653085
35Morphine addiction_Homo sapiens_hsa050321.54760897
36Huntingtons disease_Homo sapiens_hsa050161.54085342
37Caffeine metabolism_Homo sapiens_hsa002321.49249999
38Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.47117833
39Nitrogen metabolism_Homo sapiens_hsa009101.46083267
40Glycerophospholipid metabolism_Homo sapiens_hsa005641.45981854
41Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.43653312
42Maturity onset diabetes of the young_Homo sapiens_hsa049501.29904738
43Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.28524740
44Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.26432974
45Cardiac muscle contraction_Homo sapiens_hsa042601.24918021
46Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.21958202
47Non-homologous end-joining_Homo sapiens_hsa034501.21482671
48Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.18883016
49Fat digestion and absorption_Homo sapiens_hsa049751.17090294
50Lysine degradation_Homo sapiens_hsa003101.13791586
51Amphetamine addiction_Homo sapiens_hsa050311.12965061
52Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.09394173
53Ether lipid metabolism_Homo sapiens_hsa005651.07492200
54Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.06428007
55Serotonergic synapse_Homo sapiens_hsa047261.05467423
56Renin secretion_Homo sapiens_hsa049241.04324095
57Glutamatergic synapse_Homo sapiens_hsa047241.04273422
58GABAergic synapse_Homo sapiens_hsa047271.04030535
59Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.03889237
60Retinol metabolism_Homo sapiens_hsa008301.03865125
61Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.03195742
62Fructose and mannose metabolism_Homo sapiens_hsa000511.00869929
63Purine metabolism_Homo sapiens_hsa002301.00820818
64Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.00492674
65Fatty acid degradation_Homo sapiens_hsa000710.97638344
66Dorso-ventral axis formation_Homo sapiens_hsa043200.96339343
67Cysteine and methionine metabolism_Homo sapiens_hsa002700.95188339
68* Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.93594349
69Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.92548481
70Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.91593070
71Proteasome_Homo sapiens_hsa030500.91228473
72Bile secretion_Homo sapiens_hsa049760.90815282
73Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.90318264
74Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.89621224
75Fatty acid metabolism_Homo sapiens_hsa012120.88850284
76Glutathione metabolism_Homo sapiens_hsa004800.86802660
77Systemic lupus erythematosus_Homo sapiens_hsa053220.85495372
78Inositol phosphate metabolism_Homo sapiens_hsa005620.85277659
79Insulin secretion_Homo sapiens_hsa049110.84175179
80Hedgehog signaling pathway_Homo sapiens_hsa043400.84072667
81RNA transport_Homo sapiens_hsa030130.81021072
82Sulfur metabolism_Homo sapiens_hsa009200.80587805
83Phosphatidylinositol signaling system_Homo sapiens_hsa040700.79783621
84Antigen processing and presentation_Homo sapiens_hsa046120.79427640
85Chemical carcinogenesis_Homo sapiens_hsa052040.79097040
86Thyroid hormone synthesis_Homo sapiens_hsa049180.76281226
87Taste transduction_Homo sapiens_hsa047420.75871832
88mRNA surveillance pathway_Homo sapiens_hsa030150.75430185
89Synaptic vesicle cycle_Homo sapiens_hsa047210.71585601
90Collecting duct acid secretion_Homo sapiens_hsa049660.69764480
91beta-Alanine metabolism_Homo sapiens_hsa004100.69619577
92Calcium signaling pathway_Homo sapiens_hsa040200.68977487
93Arginine and proline metabolism_Homo sapiens_hsa003300.67788143
94Peroxisome_Homo sapiens_hsa041460.64214282
95Oxidative phosphorylation_Homo sapiens_hsa001900.64077697
96Circadian rhythm_Homo sapiens_hsa047100.63175552
97Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.63137221
98RNA polymerase_Homo sapiens_hsa030200.62236749
99Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.59609684
100Protein digestion and absorption_Homo sapiens_hsa049740.59419428
101Pancreatic secretion_Homo sapiens_hsa049720.58989446
102Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.58908028
103Estrogen signaling pathway_Homo sapiens_hsa049150.58618231
104Long-term depression_Homo sapiens_hsa047300.56223133
105N-Glycan biosynthesis_Homo sapiens_hsa005100.54781188
106ABC transporters_Homo sapiens_hsa020100.53753853
107Homologous recombination_Homo sapiens_hsa034400.53663320
108Sphingolipid metabolism_Homo sapiens_hsa006000.51781395
109Parkinsons disease_Homo sapiens_hsa050120.51142365
110Salivary secretion_Homo sapiens_hsa049700.50765224
111Cyanoamino acid metabolism_Homo sapiens_hsa004600.50650228
112Gastric acid secretion_Homo sapiens_hsa049710.49603356
113Long-term potentiation_Homo sapiens_hsa047200.49095158
114Steroid biosynthesis_Homo sapiens_hsa001000.46494226
115Thyroid hormone signaling pathway_Homo sapiens_hsa049190.46307232
116Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.45650318
117Dopaminergic synapse_Homo sapiens_hsa047280.44288608
118Fatty acid elongation_Homo sapiens_hsa000620.43527980
119Endocytosis_Homo sapiens_hsa041440.43464640
120Adipocytokine signaling pathway_Homo sapiens_hsa049200.43159637
121Ovarian steroidogenesis_Homo sapiens_hsa049130.42471178
122Tyrosine metabolism_Homo sapiens_hsa003500.42050400
123* Metabolic pathways_Homo sapiens_hsa011000.41800262
124Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.41415082
125Histidine metabolism_Homo sapiens_hsa003400.41378482
126cGMP-PKG signaling pathway_Homo sapiens_hsa040220.40997657
127RNA degradation_Homo sapiens_hsa030180.40535472
128Central carbon metabolism in cancer_Homo sapiens_hsa052300.39028102
129Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.38189268
130Circadian entrainment_Homo sapiens_hsa047130.37952256
131Cholinergic synapse_Homo sapiens_hsa047250.37144483
132Arachidonic acid metabolism_Homo sapiens_hsa005900.35780612
133Oxytocin signaling pathway_Homo sapiens_hsa049210.35451279
134Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.34842391
135One carbon pool by folate_Homo sapiens_hsa006700.33908953
136AMPK signaling pathway_Homo sapiens_hsa041520.31592834
137Regulation of autophagy_Homo sapiens_hsa041400.29959878
138cAMP signaling pathway_Homo sapiens_hsa040240.29490237
139Complement and coagulation cascades_Homo sapiens_hsa046100.28947297
140Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.28763707
141Salmonella infection_Homo sapiens_hsa051320.28483645
142Legionellosis_Homo sapiens_hsa051340.27849548
143Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.27489817
144Olfactory transduction_Homo sapiens_hsa047400.22209486
145Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.20310281
146Vascular smooth muscle contraction_Homo sapiens_hsa042700.18359014
147Pentose and glucuronate interconversions_Homo sapiens_hsa000400.17575251
148Cocaine addiction_Homo sapiens_hsa050300.16555419
149Cell cycle_Homo sapiens_hsa041100.15627846
150Tight junction_Homo sapiens_hsa045300.14311571
151Primary bile acid biosynthesis_Homo sapiens_hsa001200.14200269
152Steroid hormone biosynthesis_Homo sapiens_hsa001400.13470430

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