GADL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1lung lobe morphogenesis (GO:0060463)9.60751629
2lung vasculature development (GO:0060426)8.74487261
3polarized epithelial cell differentiation (GO:0030859)8.39992956
4endocardial cushion development (GO:0003197)8.23265876
5establishment of apical/basal cell polarity (GO:0035089)7.71496985
6establishment of monopolar cell polarity (GO:0061162)7.06145583
7establishment or maintenance of monopolar cell polarity (GO:0061339)7.06145583
8embryonic foregut morphogenesis (GO:0048617)6.87115620
9midgut development (GO:0007494)6.80329136
10cardiac left ventricle morphogenesis (GO:0003214)6.40059985
11positive regulation of macroautophagy (GO:0016239)6.01258725
12establishment of epithelial cell polarity (GO:0090162)5.27923069
13indolalkylamine catabolic process (GO:0046218)5.14774353
14tryptophan catabolic process (GO:0006569)5.14774353
15indole-containing compound catabolic process (GO:0042436)5.14774353
16lung morphogenesis (GO:0060425)4.74989615
17axon ensheathment in central nervous system (GO:0032291)4.72958325
18central nervous system myelination (GO:0022010)4.72958325
19auditory receptor cell stereocilium organization (GO:0060088)4.67631157
20sensory perception of smell (GO:0007608)4.62457288
21negative regulation of viral release from host cell (GO:1902187)4.61714734
22kynurenine metabolic process (GO:0070189)4.46157478
23indolalkylamine metabolic process (GO:0006586)4.43749628
24signal peptide processing (GO:0006465)4.40087819
25positive regulation of response to extracellular stimulus (GO:0032106)4.34372244
26positive regulation of response to nutrient levels (GO:0032109)4.34372244
27tryptophan metabolic process (GO:0006568)4.29554719
28pancreas development (GO:0031016)4.23699197
29renal system development (GO:0072001)4.21933285
30regulation of smooth muscle cell differentiation (GO:0051150)4.15902657
31inner ear receptor stereocilium organization (GO:0060122)4.14365084
32neuron remodeling (GO:0016322)4.13958509
33mesodermal cell differentiation (GO:0048333)4.13524809
34regulation of timing of cell differentiation (GO:0048505)3.89719930
35long-chain fatty acid biosynthetic process (GO:0042759)3.78424693
36negative regulation of exocytosis (GO:0045920)3.76134101
37detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.75833551
38cellular copper ion homeostasis (GO:0006878)3.71041959
39limb bud formation (GO:0060174)3.69754298
40L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.62636972
41embryonic digestive tract morphogenesis (GO:0048557)3.51312034
42regulation of development, heterochronic (GO:0040034)3.48198172
43UDP-N-acetylglucosamine metabolic process (GO:0006047)3.44704241
44establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)3.43912348
45presynaptic membrane organization (GO:0097090)3.42306022
46tachykinin receptor signaling pathway (GO:0007217)3.42300528
47cerebral cortex radially oriented cell migration (GO:0021799)3.40976539
48regulation of skeletal muscle contraction (GO:0014819)3.38438704
49negative regulation of viral transcription (GO:0032897)3.38027175
50neuron cell-cell adhesion (GO:0007158)3.37282061
51response to gamma radiation (GO:0010332)3.35900374
52magnesium ion transport (GO:0015693)3.32336108
53NAD biosynthetic process (GO:0009435)3.32028604
54cilium or flagellum-dependent cell motility (GO:0001539)3.31022918
55photoreceptor cell maintenance (GO:0045494)3.29436898
56presynaptic membrane assembly (GO:0097105)3.25173048
57aromatic amino acid family catabolic process (GO:0009074)3.24990787
58indole-containing compound metabolic process (GO:0042430)3.24872235
59amino acid salvage (GO:0043102)3.24842929
60L-methionine salvage (GO:0071267)3.24842929
61L-methionine biosynthetic process (GO:0071265)3.24842929
62methionine biosynthetic process (GO:0009086)3.24418084
63benzene-containing compound metabolic process (GO:0042537)3.20542314
64monoubiquitinated protein deubiquitination (GO:0035520)3.16532722
65mammary gland epithelial cell differentiation (GO:0060644)3.15058399
66negative regulation of execution phase of apoptosis (GO:1900118)3.14340400
67forebrain neuron differentiation (GO:0021879)3.11443924
68replicative senescence (GO:0090399)3.09012313
69amine catabolic process (GO:0009310)3.08715574
70cellular biogenic amine catabolic process (GO:0042402)3.08715574
71regulation of mast cell activation involved in immune response (GO:0033006)3.08622659
72sensory perception of chemical stimulus (GO:0007606)3.07017765
73mesenchymal cell differentiation involved in kidney development (GO:0072161)3.03946816
74mesenchymal cell differentiation involved in renal system development (GO:2001012)3.03946816
75positive regulation of action potential (GO:0045760)3.03843408
76detection of bacterium (GO:0016045)3.03735827
77regulation of hippo signaling (GO:0035330)3.00358111
78negative regulation of synaptic transmission, GABAergic (GO:0032229)3.00019585
79negative regulation of cytosolic calcium ion concentration (GO:0051481)2.94471292
80ganglion development (GO:0061548)2.91437681
81regulation of sarcomere organization (GO:0060297)2.89060564
82regulation of pigment cell differentiation (GO:0050932)2.88745090
83superoxide anion generation (GO:0042554)2.88657336
84cellular ketone body metabolic process (GO:0046950)2.88236138
85copper ion homeostasis (GO:0055070)2.87776128
86protein localization to cilium (GO:0061512)2.87182861
87neural tube formation (GO:0001841)2.86353512
88meiotic chromosome segregation (GO:0045132)2.85944514
89cellular response to interleukin-15 (GO:0071350)2.82925885
90keratinocyte development (GO:0003334)2.82607023
91sympathetic nervous system development (GO:0048485)2.82382698
92detection of light stimulus involved in sensory perception (GO:0050962)2.81963123
93detection of light stimulus involved in visual perception (GO:0050908)2.81963123
94detection of other organism (GO:0098543)2.80923106
95regulation of platelet aggregation (GO:0090330)2.78199495
96ketone body metabolic process (GO:1902224)2.74959354
97developmental pigmentation (GO:0048066)2.74444124
98behavioral response to ethanol (GO:0048149)2.74304053
99regulation of mast cell degranulation (GO:0043304)2.72561048
100aromatic amino acid family metabolic process (GO:0009072)2.72180225
101regulation of viral release from host cell (GO:1902186)2.70910629
102negative regulation of homotypic cell-cell adhesion (GO:0034111)2.70819150
103positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.69473685
104DNA demethylation (GO:0080111)2.67379279
105oligodendrocyte differentiation (GO:0048709)2.66368052
106reflex (GO:0060004)2.65265430
107cranial nerve structural organization (GO:0021604)2.64579134
108positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568)2.64076732
109adenosine metabolic process (GO:0046085)2.63277070
110retina layer formation (GO:0010842)2.63119169
111methionine metabolic process (GO:0006555)2.62370332
112inner ear receptor cell differentiation (GO:0060113)2.61189032
113protein K63-linked deubiquitination (GO:0070536)2.59885330
114detection of mechanical stimulus involved in sensory perception (GO:0050974)2.59675571
115regulation of mast cell activation (GO:0033003)2.58398078
116cell differentiation involved in metanephros development (GO:0072202)2.57397476
117oxidative demethylation (GO:0070989)2.56886509
118protein autoubiquitination (GO:0051865)2.56803549
119synapsis (GO:0007129)2.55441360
120regulation of mitochondrial translation (GO:0070129)2.55321988
121fucose catabolic process (GO:0019317)2.54792562
122L-fucose metabolic process (GO:0042354)2.54792562
123L-fucose catabolic process (GO:0042355)2.54792562
124cardiac ventricle morphogenesis (GO:0003208)2.54537089
125regulation of collateral sprouting (GO:0048670)2.53468124
126facial nerve structural organization (GO:0021612)2.50494421
127nonmotile primary cilium assembly (GO:0035058)2.50059570
128regulation of macroautophagy (GO:0016241)2.49623470
129postsynaptic membrane organization (GO:0001941)2.49488060
130behavioral response to nicotine (GO:0035095)2.45930154
131pyridine nucleotide biosynthetic process (GO:0019363)2.45553801
132nicotinamide nucleotide biosynthetic process (GO:0019359)2.45553801
133phasic smooth muscle contraction (GO:0014821)2.45463905
134mechanoreceptor differentiation (GO:0042490)2.44041507
135DNA double-strand break processing (GO:0000729)2.42667417
136G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.42573696
137neutrophil activation (GO:0042119)2.41394612
138respiratory chain complex IV assembly (GO:0008535)2.40340481
139calcium ion import (GO:0070509)2.39939870
140serotonin receptor signaling pathway (GO:0007210)2.39555603
141auditory receptor cell differentiation (GO:0042491)2.39492679
142cranial nerve morphogenesis (GO:0021602)2.39403938
143import into cell (GO:0098657)2.38583902
144cell proliferation in forebrain (GO:0021846)2.38456138
145polyketide metabolic process (GO:0030638)2.37881971
146doxorubicin metabolic process (GO:0044598)2.37881971
147daunorubicin metabolic process (GO:0044597)2.37881971
148neuronal action potential (GO:0019228)2.37771448
149negative regulation of myoblast differentiation (GO:0045662)2.37558762
150serotonin metabolic process (GO:0042428)2.37539699
151establishment of protein localization to Golgi (GO:0072600)2.36863248
152negative regulation of protein localization to cell surface (GO:2000009)2.36053488
153response to pheromone (GO:0019236)2.35942138
154kidney morphogenesis (GO:0060993)2.34162089
155positive regulation of uterine smooth muscle contraction (GO:0070474)2.34100909
156gamma-aminobutyric acid transport (GO:0015812)2.32613475
157aspartate family amino acid biosynthetic process (GO:0009067)2.31963229
158mesonephros development (GO:0001823)2.31778127
159cellular response to sterol (GO:0036315)2.30717303
160protein K48-linked deubiquitination (GO:0071108)2.30329253
161negative regulation of neurotransmitter transport (GO:0051589)2.29843054
162spinal cord association neuron differentiation (GO:0021527)2.29186097
163negative regulation of mast cell activation (GO:0033004)2.28660643
164glycerophospholipid catabolic process (GO:0046475)2.27953304
165mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.27599724
166mitochondrial respiratory chain complex I assembly (GO:0032981)2.27599724
167NADH dehydrogenase complex assembly (GO:0010257)2.27599724
168regulation of somitogenesis (GO:0014807)2.27534440
169startle response (GO:0001964)2.27389430
170positive regulation of interleukin-10 production (GO:0032733)2.26845544
171negative regulation of leukocyte chemotaxis (GO:0002689)2.26636489
172GPI anchor metabolic process (GO:0006505)2.25681529
173left/right axis specification (GO:0070986)2.24302627
174forebrain neuron development (GO:0021884)2.24023631
175GPI anchor biosynthetic process (GO:0006506)2.23915018
176G-protein coupled receptor internalization (GO:0002031)2.23622258
177neuron recognition (GO:0008038)2.23306382
178dendritic cell chemotaxis (GO:0002407)2.23250748
179cytochrome complex assembly (GO:0017004)2.22994445
180spinal cord motor neuron differentiation (GO:0021522)2.22965046
181response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.22575000
182interferon-gamma production (GO:0032609)2.22548316
183regulation of inositol phosphate biosynthetic process (GO:0010919)2.21944773
184positive regulation of cellular amide metabolic process (GO:0034250)2.19949385
185histone H2B ubiquitination (GO:0033523)2.19798852
186polyol transport (GO:0015791)2.19613272
187cilium movement (GO:0003341)2.19370853
188detection of calcium ion (GO:0005513)2.18162235
189cell differentiation in spinal cord (GO:0021515)2.17317768
190cardiac ventricle formation (GO:0003211)2.17110967
191centriole assembly (GO:0098534)2.14723356
192preassembly of GPI anchor in ER membrane (GO:0016254)2.12944962
193cornea development in camera-type eye (GO:0061303)2.12588693
194respiratory tube development (GO:0030323)10.0460225

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.25387615
2GBX2_23144817_ChIP-Seq_PC3_Human3.76289876
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.89856865
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.57541334
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.57022830
6ZNF274_21170338_ChIP-Seq_K562_Hela2.57005547
7ZFP57_27257070_Chip-Seq_ESCs_Mouse2.53554173
8BMI1_23680149_ChIP-Seq_NPCS_Mouse2.51522861
9VDR_22108803_ChIP-Seq_LS180_Human2.48672308
10EED_16625203_ChIP-ChIP_MESCs_Mouse2.48343875
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.43412620
12IGF1R_20145208_ChIP-Seq_DFB_Human2.42589550
13GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.37113019
14SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.35653620
15CBX2_27304074_Chip-Seq_ESCs_Mouse2.28899677
16EWS_26573619_Chip-Seq_HEK293_Human2.25039166
17SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.21207910
18SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.20983741
19EZH2_18974828_ChIP-Seq_MESCs_Mouse2.18396775
20RNF2_18974828_ChIP-Seq_MESCs_Mouse2.18396775
21SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.16443842
22SALL1_21062744_ChIP-ChIP_HESCs_Human2.15596475
23AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.12014203
24TAF15_26573619_Chip-Seq_HEK293_Human2.04296136
25JARID2_20075857_ChIP-Seq_MESCs_Mouse2.03998049
26SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.00479245
27RNF2_27304074_Chip-Seq_NSC_Mouse1.91305034
28EZH2_27294783_Chip-Seq_ESCs_Mouse1.91294136
29RNF2_27304074_Chip-Seq_ESCs_Mouse1.90557437
30SUZ12_27294783_Chip-Seq_ESCs_Mouse1.86412910
31* STAT3_23295773_ChIP-Seq_U87_Human1.81133210
32RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.79448343
33BCAT_22108803_ChIP-Seq_LS180_Human1.78260334
34PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.77862449
35GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.74848464
36PCGF2_27294783_Chip-Seq_ESCs_Mouse1.74337215
37* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.72116988
38GATA1_22025678_ChIP-Seq_K562_Human1.71937869
39SUZ12_27294783_Chip-Seq_NPCs_Mouse1.70651891
40SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.67466631
41* P300_19829295_ChIP-Seq_ESCs_Human1.67352133
42POU3F2_20337985_ChIP-ChIP_501MEL_Human1.62415961
43MTF2_20144788_ChIP-Seq_MESCs_Mouse1.61607250
44EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.61102201
45TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.60587609
46SMAD_19615063_ChIP-ChIP_OVARY_Human1.59285519
47NANOG_18555785_Chip-Seq_ESCs_Mouse1.58347319
48PCGF2_27294783_Chip-Seq_NPCs_Mouse1.58283735
49POU5F1_16153702_ChIP-ChIP_HESCs_Human1.57852302
50NFE2_27457419_Chip-Seq_LIVER_Mouse1.57131318
51FLI1_27457419_Chip-Seq_LIVER_Mouse1.56446233
52SUZ12_18555785_Chip-Seq_ESCs_Mouse1.55930336
53TCF4_23295773_ChIP-Seq_U87_Human1.53982689
54E2F1_18555785_Chip-Seq_ESCs_Mouse1.50470334
55RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.50023492
56CTBP1_25329375_ChIP-Seq_LNCAP_Human1.45778985
57P53_22387025_ChIP-Seq_ESCs_Mouse1.44658822
58AR_25329375_ChIP-Seq_VCAP_Human1.44631364
59* SMAD3_21741376_ChIP-Seq_EPCs_Human1.43981363
60EGR1_23403033_ChIP-Seq_LIVER_Mouse1.43620027
61STAT3_18555785_Chip-Seq_ESCs_Mouse1.43269847
62BP1_19119308_ChIP-ChIP_Hs578T_Human1.42934209
63EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.42136488
64CMYC_18555785_Chip-Seq_ESCs_Mouse1.41789883
65* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.40848388
66* CBP_20019798_ChIP-Seq_JUKART_Human1.40848388
67NANOG_19829295_ChIP-Seq_ESCs_Human1.40845259
68SOX2_19829295_ChIP-Seq_ESCs_Human1.40845259
69CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.40320027
70CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.39658284
71TP53_22573176_ChIP-Seq_HFKS_Human1.39488307
72CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39164755
73CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.39007930
74P300_18555785_Chip-Seq_ESCs_Mouse1.38452116
75DROSHA_22980978_ChIP-Seq_HELA_Human1.38117513
76EZH2_27294783_Chip-Seq_NPCs_Mouse1.37447812
77AR_21572438_ChIP-Seq_LNCaP_Human1.35460777
78SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.34608385
79SMAD4_21799915_ChIP-Seq_A2780_Human1.34252153
80RUNX1_27457419_Chip-Seq_LIVER_Mouse1.34108666
81STAT6_21828071_ChIP-Seq_BEAS2B_Human1.33580438
82POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.33490307
83TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.33490307
84TCF4_22108803_ChIP-Seq_LS180_Human1.33144103
85PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.32324393
86PIAS1_25552417_ChIP-Seq_VCAP_Human1.31384575
87NMYC_18555785_Chip-Seq_ESCs_Mouse1.30557793
88SMAD4_21741376_ChIP-Seq_EPCs_Human1.30402724
89SOX2_18555785_Chip-Seq_ESCs_Mouse1.29679574
90MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.29432495
91* EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.29322885
92NOTCH1_21737748_ChIP-Seq_TLL_Human1.28402298
93CDX2_22108803_ChIP-Seq_LS180_Human1.28221459
94EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.28210721
95CTBP2_25329375_ChIP-Seq_LNCAP_Human1.27897005
96ER_23166858_ChIP-Seq_MCF-7_Human1.27756820
97HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.27632106
98TAL1_26923725_Chip-Seq_HPCs_Mouse1.27565747
99FUS_26573619_Chip-Seq_HEK293_Human1.26710028
100OCT4_18555785_Chip-Seq_ESCs_Mouse1.26629289
101* PRDM14_20953172_ChIP-Seq_ESCs_Human1.26000338
102ZFX_18555785_Chip-Seq_ESCs_Mouse1.25137493
103PU1_27457419_Chip-Seq_LIVER_Mouse1.23306605
104REST_21632747_ChIP-Seq_MESCs_Mouse1.23272223
105OCT4_21477851_ChIP-Seq_ESCs_Mouse1.22844700
106TOP2B_26459242_ChIP-Seq_MCF-7_Human1.22693104
107KLF5_20875108_ChIP-Seq_MESCs_Mouse1.20839982
108KLF4_18555785_Chip-Seq_ESCs_Mouse1.20288717
109TP53_16413492_ChIP-PET_HCT116_Human1.20161240
110TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.20007231
111SMAD1_18555785_Chip-Seq_ESCs_Mouse1.17231539
112MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.16075120
113CTCF_18555785_Chip-Seq_ESCs_Mouse1.15703053
114ESRRB_18555785_Chip-Seq_ESCs_Mouse1.15571542
115ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.15550867
116FLI1_21867929_ChIP-Seq_TH2_Mouse1.15178820
117VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.15026696
118SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.14888437
119SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.14588700
120LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.13351270
121IKZF1_21737484_ChIP-ChIP_HCT116_Human1.12313026
122SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.12196606
123* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.12102111
124OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12031093
125TP53_18474530_ChIP-ChIP_U2OS_Human1.11607789
126* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08024965
127BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.07874310
128FOXA1_21572438_ChIP-Seq_LNCaP_Human1.07498497
129KDM2B_26808549_Chip-Seq_REH_Human1.07364111
130HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.07208742
131NRF2_20460467_ChIP-Seq_MEFs_Mouse1.06970403
132NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.06970403
133MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.06624961
134CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.04815750
135CRX_20693478_ChIP-Seq_RETINA_Mouse1.04742136
136CDX2_19796622_ChIP-Seq_MESCs_Mouse1.04269593
137RUNX2_22187159_ChIP-Seq_PCA_Human1.02603299
138ARNT_22903824_ChIP-Seq_MCF-7_Human1.01778088
139NR3C1_21868756_ChIP-Seq_MCF10A_Human1.01642986
140AHR_22903824_ChIP-Seq_MCF-7_Human1.00798394
141* SOX2_21211035_ChIP-Seq_LN229_Gbm0.97108069
142FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.96193415

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.19553089
2MP0000566_synostosis4.07105509
3MP0001984_abnormal_olfaction4.00179575
4MP0003646_muscle_fatigue3.84483800
5MP0003195_calcinosis3.63530604
6MP0006292_abnormal_olfactory_placode3.46777872
7MP0002277_abnormal_respiratory_mucosa3.29041017
8MP0003136_yellow_coat_color3.27783029
9MP0000569_abnormal_digit_pigmentation3.16344738
10MP0001188_hyperpigmentation3.13654790
11MP0004145_abnormal_muscle_electrophysio2.98487375
12MP0002102_abnormal_ear_morphology2.91656765
13MP0004742_abnormal_vestibular_system2.90380683
14MP0003880_abnormal_central_pattern2.82370565
15MP0004381_abnormal_hair_follicle2.67478667
16MP0004043_abnormal_pH_regulation2.64071836
17MP0005645_abnormal_hypothalamus_physiol2.50475751
18MP0005171_absent_coat_pigmentation2.40661738
19MP0001486_abnormal_startle_reflex2.38104126
20MP0000427_abnormal_hair_cycle2.19027664
21MP0005409_darkened_coat_color2.07887543
22MP0008789_abnormal_olfactory_epithelium2.03572259
23MP0002837_dystrophic_cardiac_calcinosis1.99770852
24MP0008058_abnormal_DNA_repair1.81008551
25MP0010094_abnormal_chromosome_stability1.80277323
26MP0008872_abnormal_physiological_respon1.79272386
27MP0008877_abnormal_DNA_methylation1.78999010
28MP0005423_abnormal_somatic_nervous1.77413485
29MP0004036_abnormal_muscle_relaxation1.76246437
30MP0001485_abnormal_pinna_reflex1.73208383
31MP0005174_abnormal_tail_pigmentation1.68437630
32MP0001346_abnormal_lacrimal_gland1.66065935
33MP0000015_abnormal_ear_pigmentation1.65973151
34MP0005394_taste/olfaction_phenotype1.65644845
35MP0005499_abnormal_olfactory_system1.65644845
36MP0005310_abnormal_salivary_gland1.63546362
37MP0000026_abnormal_inner_ear1.61888326
38MP0002138_abnormal_hepatobiliary_system1.61228240
39MP0008260_abnormal_autophagy1.53846125
40MP0004147_increased_porphyrin_level1.53836766
41MP0000749_muscle_degeneration1.53768861
42MP0001963_abnormal_hearing_physiology1.53184922
43MP0003252_abnormal_bile_duct1.52247318
44MP0005646_abnormal_pituitary_gland1.51671289
45MP0004215_abnormal_myocardial_fiber1.50312320
46MP0002272_abnormal_nervous_system1.48603733
47MP0003045_fibrosis1.48170384
48MP0006276_abnormal_autonomic_nervous1.47045841
49MP0006054_spinal_hemorrhage1.45994908
50MP0000778_abnormal_nervous_system1.43273439
51MP0002557_abnormal_social/conspecific_i1.43233155
52MP0002184_abnormal_innervation1.43057030
53MP0002735_abnormal_chemical_nociception1.42536203
54MP0003718_maternal_effect1.41160953
55MP0003938_abnormal_ear_development1.38149330
56MP0000920_abnormal_myelination1.37427025
57MP0001968_abnormal_touch/_nociception1.36665245
58MP0005266_abnormal_metabolism1.36653837
59MP0002098_abnormal_vibrissa_morphology1.35915467
60MP0005379_endocrine/exocrine_gland_phen1.35727518
61MP0002572_abnormal_emotion/affect_behav1.35657674
62MP0009379_abnormal_foot_pigmentation1.34129354
63MP0006036_abnormal_mitochondrial_physio1.30166949
64MP0009745_abnormal_behavioral_response1.29360293
65MP0003941_abnormal_skin_development1.29349161
66MP0002938_white_spotting1.28264973
67MP0005551_abnormal_eye_electrophysiolog1.28226476
68MP0000371_diluted_coat_color1.27792900
69MP0004142_abnormal_muscle_tone1.26267562
70MP0002752_abnormal_somatic_nervous1.26156155
71MP0001986_abnormal_taste_sensitivity1.26087417
72MP0002638_abnormal_pupillary_reflex1.21900750
73MP0000049_abnormal_middle_ear1.21500282
74MP0000372_irregular_coat_pigmentation1.20737591
75MP0000631_abnormal_neuroendocrine_gland1.18035840
76MP0000538_abnormal_urinary_bladder1.16101958
77MP0004859_abnormal_synaptic_plasticity1.15352543
78MP0002928_abnormal_bile_duct1.15300486
79MP0002132_abnormal_respiratory_system1.15251633
80MP0002734_abnormal_mechanical_nocicepti1.15087756
81MP0002736_abnormal_nociception_after1.14016735
82MP0005377_hearing/vestibular/ear_phenot1.13716880
83MP0003878_abnormal_ear_physiology1.13716880
84MP0002067_abnormal_sensory_capabilities1.13489035
85MP0005620_abnormal_muscle_contractility1.11455629
86MP0009046_muscle_twitch1.10307008
87MP0001348_abnormal_lacrimal_gland1.09656410
88MP0005670_abnormal_white_adipose1.09321766
89MP0002249_abnormal_larynx_morphology1.09073480
90MP0002064_seizures1.08454588
91MP0004484_altered_response_of1.07896128
92MP0005085_abnormal_gallbladder_physiolo1.07196541
93MP0005075_abnormal_melanosome_morpholog1.06359702
94MP0003950_abnormal_plasma_membrane1.05492816
95MP0004084_abnormal_cardiac_muscle1.04482956
96MP0003635_abnormal_synaptic_transmissio1.03755055
97MP0002233_abnormal_nose_morphology1.02922845
98MP0002163_abnormal_gland_morphology1.02627891
99MP0001970_abnormal_pain_threshold1.01816543
100MP0004270_analgesia1.01426272
101MP0005408_hypopigmentation1.00667705
102MP0010386_abnormal_urinary_bladder0.99676175
103MP0005395_other_phenotype0.98138209
104MP0004134_abnormal_chest_morphology0.97422495
105MP0000762_abnormal_tongue_morphology0.95267151
106MP0002168_other_aberrant_phenotype0.95108624
107MP0002095_abnormal_skin_pigmentation0.94850088
108MP0000230_abnormal_systemic_arterial0.93220767
109MP0002063_abnormal_learning/memory/cond0.92535025
110MP0008995_early_reproductive_senescence0.92431996
111MP0009697_abnormal_copulation0.91749866
112MP0008004_abnormal_stomach_pH0.90730405
113MP0003137_abnormal_impulse_conducting0.90618883
114MP0005410_abnormal_fertilization0.89857120
115MP0002882_abnormal_neuron_morphology0.89428370
116MP0006072_abnormal_retinal_apoptosis0.89156756
117MP0005451_abnormal_body_composition0.89027518
118MP0001186_pigmentation_phenotype0.87042918
119MP0001905_abnormal_dopamine_level0.86822186
120MP0002148_abnormal_hypersensitivity_rea0.86657772
121MP0000579_abnormal_nail_morphology0.86576577
122MP0001440_abnormal_grooming_behavior0.86424460
123MP0000613_abnormal_salivary_gland0.86088492
124MP0009250_abnormal_appendicular_skeleto0.85862067
125MP0005167_abnormal_blood-brain_barrier0.85483759
126MP0002693_abnormal_pancreas_physiology0.84258365
127MP0005253_abnormal_eye_physiology0.83964182
128MP0002332_abnormal_exercise_endurance0.83284858
129MP0001529_abnormal_vocalization0.83232931
130MP0002234_abnormal_pharynx_morphology0.83112087
131MP0001790_abnormal_immune_system0.82281846
132MP0005387_immune_system_phenotype0.82281846
133MP0003806_abnormal_nucleotide_metabolis0.80853666
134MP0004924_abnormal_behavior0.79556244
135MP0005386_behavior/neurological_phenoty0.79556244
136MP0002751_abnormal_autonomic_nervous0.79195639
137MP0004130_abnormal_muscle_cell0.78877612
138MP0002106_abnormal_muscle_physiology0.78640916
139MP0000462_abnormal_digestive_system0.78528017
140MP0002177_abnormal_outer_ear0.77613841
141MP0000383_abnormal_hair_follicle0.75443029
142MP0005257_abnormal_intraocular_pressure0.73667884
143MP0003698_abnormal_male_reproductive0.72736119
144MP0003786_premature_aging0.72159990
145MP0001501_abnormal_sleep_pattern0.71665021
146MP0002876_abnormal_thyroid_physiology0.70888554
147MP0005084_abnormal_gallbladder_morpholo0.69896283
148MP0005647_abnormal_sex_gland0.69835365
149MP0008775_abnormal_heart_ventricle0.68475648
150MP0005195_abnormal_posterior_eye0.68330196
151MP0003693_abnormal_embryo_hatching0.67141418
152MP0001664_abnormal_digestion0.66867037
153MP0001502_abnormal_circadian_rhythm0.66691093
154MP0002733_abnormal_thermal_nociception0.64672196
155MP0003879_abnormal_hair_cell0.64111953
156MP0002229_neurodegeneration0.63690886

Predicted human phenotypes

RankGene SetZ-score
1Intestinal atresia (HP:0011100)9.46408028
2Annular pancreas (HP:0001734)5.93201525
3Abnormality of the fetal cardiovascular system (HP:0010948)5.03171503
4Abnormal umbilical cord blood vessels (HP:0011403)5.03171503
5Single umbilical artery (HP:0001195)5.03171503
6Absent rod-and cone-mediated responses on ERG (HP:0007688)4.80506442
7Hydroureter (HP:0000072)4.79836013
8Parakeratosis (HP:0001036)4.67677101
9Meckel diverticulum (HP:0002245)4.53788260
10Abnormality of the ileum (HP:0001549)4.44961859
11Gastrointestinal atresia (HP:0002589)4.39025079
12Septo-optic dysplasia (HP:0100842)4.11856103
13Decreased central vision (HP:0007663)4.07246091
14Neonatal death (HP:0003811)3.90884834
15Abnormal lung lobation (HP:0002101)3.83287610
16Hypoplastic left heart (HP:0004383)3.79128687
17Abnormal rod and cone electroretinograms (HP:0008323)3.58440338
18Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.58340549
19Nemaline bodies (HP:0003798)3.41914830
20Absent/shortened dynein arms (HP:0200106)3.41587447
21Dynein arm defect of respiratory motile cilia (HP:0012255)3.41587447
22Pancreatic cysts (HP:0001737)3.40222148
23Abnormal ciliary motility (HP:0012262)3.36334595
24Hypoplastic heart (HP:0001961)3.33589520
25Bony spicule pigmentary retinopathy (HP:0007737)3.26482323
26Febrile seizures (HP:0002373)3.22219309
27Chromosomal breakage induced by crosslinking agents (HP:0003221)3.17972650
28Gaze-evoked nystagmus (HP:0000640)3.16533621
29Attenuation of retinal blood vessels (HP:0007843)3.15139644
30Small intestinal stenosis (HP:0012848)3.14425337
31Duodenal stenosis (HP:0100867)3.14425337
32White forelock (HP:0002211)3.12386295
33Central scotoma (HP:0000603)3.11802323
34Patchy hypopigmentation of hair (HP:0011365)3.11500537
35Absent septum pellucidum (HP:0001331)3.09988024
36Muscle fiber inclusion bodies (HP:0100299)3.03857410
37Abnormality of the umbilical cord (HP:0010881)3.03383991
38Abnormal respiratory motile cilium physiology (HP:0012261)3.01940842
39Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.99870516
40Abnormal respiratory epithelium morphology (HP:0012253)2.97188402
41Abnormal respiratory motile cilium morphology (HP:0005938)2.97188402
42Focal motor seizures (HP:0011153)2.90946022
43Complete atrioventricular canal defect (HP:0001674)2.89826839
44Pancreatic fibrosis (HP:0100732)2.77261843
45Tubulointerstitial nephritis (HP:0001970)2.76608291
46Aplasia cutis congenita (HP:0001057)2.74647628
47Abnormality of the septum pellucidum (HP:0007375)2.72151023
48Duplicated collecting system (HP:0000081)2.71848021
49Genetic anticipation (HP:0003743)2.71084637
50Abnormality of the duodenum (HP:0002246)2.68424591
51Abnormality of incisor morphology (HP:0011063)2.67053795
52Hypothermia (HP:0002045)2.65867648
53Conical tooth (HP:0000698)2.65125321
54Chromsome breakage (HP:0040012)2.59099409
55Optic nerve hypoplasia (HP:0000609)2.54549697
56Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.48502496
57Abnormality of the renal collecting system (HP:0004742)2.48249157
58Progressive cerebellar ataxia (HP:0002073)2.45800960
59Facial diplegia (HP:0001349)2.43192398
60Decreased electroretinogram (ERG) amplitude (HP:0000654)2.41261153
61Congenital sensorineural hearing impairment (HP:0008527)2.38229921
62Xerostomia (HP:0000217)2.28154774
63Duplication of thumb phalanx (HP:0009942)2.26998223
64Abnormality of the axillary hair (HP:0100134)2.25445534
65Abnormality of secondary sexual hair (HP:0009888)2.25445534
66Abnormality of the renal cortex (HP:0011035)2.25190038
67Colon cancer (HP:0003003)2.24862475
68Medial flaring of the eyebrow (HP:0010747)2.22636690
69Nasolacrimal duct obstruction (HP:0000579)2.22522418
70Fair hair (HP:0002286)2.18462329
71Atrioventricular canal defect (HP:0006695)2.14878126
72Muscle hypertrophy of the lower extremities (HP:0008968)2.14352915
73Congenital stationary night blindness (HP:0007642)2.13102387
74Distal arthrogryposis (HP:0005684)2.12967773
75Abnormality of the lacrimal duct (HP:0011481)2.12906070
76Calf muscle hypertrophy (HP:0008981)2.12767466
77Tubulointerstitial abnormality (HP:0001969)2.11820232
78Popliteal pterygium (HP:0009756)2.08904989
79Optic neuritis (HP:0100653)2.08652032
80Retrobulbar optic neuritis (HP:0100654)2.08652032
81Hypoproteinemia (HP:0003075)2.08142040
82Abnormality of alanine metabolism (HP:0010916)2.08067578
83Hyperalaninemia (HP:0003348)2.08067578
84Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.08067578
85Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.06845738
86Constricted visual fields (HP:0001133)2.05520896
87Aplasia/Hypoplasia of the tibia (HP:0005772)2.05174519
88Nephrogenic diabetes insipidus (HP:0009806)2.04035907
89Cystic liver disease (HP:0006706)2.03801353
90Decreased lacrimation (HP:0000633)2.03527110
91Reduced antithrombin III activity (HP:0001976)2.01192820
92Osteomalacia (HP:0002749)2.00461812
93Absent eyebrow (HP:0002223)2.00317316
94Neoplasm of the adrenal cortex (HP:0100641)1.99600217
95Agammaglobulinemia (HP:0004432)1.98275181
96Vaginal atresia (HP:0000148)1.97911472
97Abnormal hair whorl (HP:0010721)1.97705213
98Rhinitis (HP:0012384)1.97369162
99Cheilitis (HP:0100825)1.97204672
100Sex reversal (HP:0012245)1.95059150
101Abnormal sex determination (HP:0012244)1.95059150
102Type II lissencephaly (HP:0007260)1.94838371
103Hyperventilation (HP:0002883)1.93539704
104True hermaphroditism (HP:0010459)1.93006370
105Scotoma (HP:0000575)1.92583471
106Methylmalonic acidemia (HP:0002912)1.92486351
107Gait imbalance (HP:0002141)1.92011195
108Lip pit (HP:0100267)1.91805787
109Cupped ear (HP:0000378)1.90008904
110Protruding tongue (HP:0010808)1.89748367
111Genital tract atresia (HP:0001827)1.89627399
112Recurrent pneumonia (HP:0006532)1.89240979
113Abnormal finger flexion creases (HP:0006143)1.88323824
114Increased corneal curvature (HP:0100692)1.87924841
115Keratoconus (HP:0000563)1.87924841
116Aplasia/Hypoplasia of the fovea (HP:0008060)1.87711547
117Hypoplasia of the fovea (HP:0007750)1.87711547
118Recurrent sinusitis (HP:0011108)1.87210147
119Abnormality of the nasolacrimal system (HP:0000614)1.86652662
120Limb dystonia (HP:0002451)1.84889909
121Renal agenesis (HP:0000104)1.84739225
122Abnormality of molar morphology (HP:0011070)1.84640936
123Abnormality of molar (HP:0011077)1.84640936
124Aplasia/Hypoplasia of the lens (HP:0008063)1.83029456
125Prostate neoplasm (HP:0100787)1.82971908
126Congenital primary aphakia (HP:0007707)1.82659472
127Myelomeningocele (HP:0002475)1.82184269
128Renal tubular acidosis (HP:0001947)1.81944815
129Abnormality of the fovea (HP:0000493)1.81943362
130Astigmatism (HP:0000483)1.81777961
131Submucous cleft hard palate (HP:0000176)1.81484827
132Alacrima (HP:0000522)1.81112058
133Methylmalonic aciduria (HP:0012120)1.80939894
134Renal cortical cysts (HP:0000803)1.80709709
135Molar tooth sign on MRI (HP:0002419)1.80031543
136Abnormality of midbrain morphology (HP:0002418)1.80031543
137Abnormality of the pulmonary veins (HP:0011718)1.79541794
138Preaxial hand polydactyly (HP:0001177)1.79361480
139Nephronophthisis (HP:0000090)1.78936226
140Furrowed tongue (HP:0000221)1.77946823
141Clumsiness (HP:0002312)1.76593583
142Inability to walk (HP:0002540)1.76210991
143Ileus (HP:0002595)1.76099386
144Anomalous pulmonary venous return (HP:0010772)1.75962124
145Degeneration of the lateral corticospinal tracts (HP:0002314)1.75336124
146Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.75336124
147Upper limb muscle weakness (HP:0003484)1.74888519
148Aplasia/Hypoplasia of the uvula (HP:0010293)1.74391967
149Peripheral hypomyelination (HP:0007182)1.74369349
150Increased CSF lactate (HP:0002490)1.73837038
151Poor speech (HP:0002465)1.73413151
152Ketoacidosis (HP:0001993)1.71549440
153Hyperglycinemia (HP:0002154)1.71335627
154Chronic hepatic failure (HP:0100626)1.70474646
155Retinal dysplasia (HP:0007973)1.70420117
156Abolished electroretinogram (ERG) (HP:0000550)1.70209822
157Type I transferrin isoform profile (HP:0003642)1.69898589
158Morphological abnormality of the middle ear (HP:0008609)1.69876899
159Abnormality of macular pigmentation (HP:0008002)1.69794172
160Abnormality of the dental root (HP:0006486)1.68740323
161Taurodontia (HP:0000679)1.68740323
162Abnormality of permanent molar morphology (HP:0011071)1.68740323
163Corneal dystrophy (HP:0001131)1.68228713
164Aganglionic megacolon (HP:0002251)1.68209789
165Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.67935133
166Abnormal protein N-linked glycosylation (HP:0012347)1.67935133
167Abnormal protein glycosylation (HP:0012346)1.67935133
168Abnormal glycosylation (HP:0012345)1.67935133
169Abnormality of the renal medulla (HP:0100957)1.67808412
170Dialeptic seizures (HP:0011146)1.67489249
171Increased neuronal autofluorescent lipopigment (HP:0002074)1.67076646
172Midline defect of the nose (HP:0004122)1.66756580
173Hypoplastic ischia (HP:0003175)1.65852262
174Sclerocornea (HP:0000647)1.64103525

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK8.14622141
2CDK197.98871043
3CASK3.90530403
4SIK32.33330081
5ACVR1B2.29354357
6TAF12.18885568
7BMPR1B2.10484983
8EIF2AK32.10114167
9BLK2.09421751
10TNIK2.04403299
11PKN12.02023051
12PINK11.91728070
13NME11.80284639
14VRK21.72843901
15INSRR1.71980970
16ADRBK21.69803271
17PRPF4B1.68962159
18MAP4K21.67720322
19BMPR21.65789561
20NEK61.62819371
21CCNB11.58620333
22STK161.56256064
23MUSK1.52627669
24MKNK21.49341757
25IRAK31.44802251
26TLK11.40263569
27TXK1.39567266
28IRAK41.38378186
29IRAK11.38237806
30SIK21.37548931
31MAP3K141.36854432
32GRK11.36648151
33WNK31.34414772
34MAPK131.32080127
35EPHA31.31445717
36STK38L1.30850423
37OXSR11.30400159
38MAP3K101.28809829
39TAOK31.28665004
40YES11.28417697
41STK391.27214592
42GRK71.26252530
43CSNK1A1L1.25578611
44MAP3K41.17759247
45BCR1.17490819
46PHKG21.16197026
47PHKG11.16197026
48KIT1.12117516
49EIF2AK21.05109073
50MAP2K71.03276835
51CSNK1G30.99663256
52CDK80.98243687
53MAPK150.94491714
54MAP4K10.92836501
55LATS10.92095177
56STK30.91748545
57MELK0.89957698
58FER0.89589143
59MAP3K130.87844159
60ZAK0.87466892
61CLK10.85458541
62CDK30.84349593
63PLK30.83769545
64TNK20.83422007
65VRK10.82933471
66AKT30.82887068
67FGR0.82398640
68STK240.79113294
69MKNK10.78567782
70EPHB20.78418401
71CSNK1G10.76882726
72RIPK40.76857679
73MAP3K70.76561297
74CAMK2B0.73582015
75IRAK20.72794736
76DYRK20.71247061
77PIK3CA0.71201276
78PLK20.70871401
79MARK10.70515926
80TRPM70.69820003
81NLK0.69148321
82MAPK120.68424062
83BUB10.68019740
84PRKCE0.67952849
85TIE10.66214259
86MST40.65405523
87CSNK1G20.64505187
88NUAK10.64459651
89LIMK10.62903949
90NTRK30.62516744
91MAP2K60.61701644
92MAPKAPK50.61668722
93PDK20.60802751
94MARK30.60658246
95EPHA40.60518562
96IKBKB0.60177409
97WNK10.58984316
98FES0.58707690
99NTRK20.58460444
100CAMK2A0.57608941
101PTK2B0.57518357
102BRD40.56671372
103SRPK10.55959015
104PRKD20.55534300
105CAMK2D0.55524802
106ERBB30.54781978
107PAK30.54192241
108ATR0.53910434
109BRSK20.53603216
110PRKCQ0.53428235
111DYRK1A0.51351347
112RPS6KA40.51283113
113OBSCN0.50038017
114DAPK20.49984798
115ROCK20.49556100
116SGK4940.49179898
117SGK2230.49179898
118PRKAA10.48108120
119WEE10.47919190
120TGFBR10.47510202
121LYN0.42136738
122DAPK10.42038626
123PRKG10.41851197
124MAPKAPK30.41618911
125CAMK2G0.41187883
126ITK0.40662675
127PRKACA0.40526441
128MAPK70.40013733
129PRKCG0.39456522
130SYK0.39258079
131EIF2AK10.38820575
132TTK0.38722166
133MARK20.37537541
134GRK50.36923227
135ATM0.36621390
136STK40.35759956
137CAMK10.35249456
138MAP3K120.34392774
139TEC0.33840380
140PRKAA20.33287284
141CSNK1A10.32699808
142PIK3CG0.32067584
143TRIM280.31672317
144PRKACB0.31078910
145ADRBK10.30937377
146CHEK20.30533550
147EPHB10.29968493
148IKBKE0.28967974
149RPS6KA50.28890585

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047403.35066387
2Butanoate metabolism_Homo sapiens_hsa006503.16690438
3Tryptophan metabolism_Homo sapiens_hsa003802.73547999
4Phototransduction_Homo sapiens_hsa047442.52522632
5Nicotine addiction_Homo sapiens_hsa050332.29136766
6One carbon pool by folate_Homo sapiens_hsa006702.19151590
7Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.19107420
8Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.11501345
9Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.09486896
10Propanoate metabolism_Homo sapiens_hsa006402.07900177
11African trypanosomiasis_Homo sapiens_hsa051432.05964530
12Taste transduction_Homo sapiens_hsa047422.00821876
13Serotonergic synapse_Homo sapiens_hsa047261.95914716
14Sphingolipid metabolism_Homo sapiens_hsa006001.90835167
15Morphine addiction_Homo sapiens_hsa050321.83939572
16Axon guidance_Homo sapiens_hsa043601.82252163
17Arachidonic acid metabolism_Homo sapiens_hsa005901.79875043
18RNA polymerase_Homo sapiens_hsa030201.79820204
19Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.79711335
20Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.76808051
21Primary bile acid biosynthesis_Homo sapiens_hsa001201.70082370
22Nitrogen metabolism_Homo sapiens_hsa009101.65784419
23Autoimmune thyroid disease_Homo sapiens_hsa053201.65411158
24Ether lipid metabolism_Homo sapiens_hsa005651.59655336
25Non-homologous end-joining_Homo sapiens_hsa034501.55056663
26Glutamatergic synapse_Homo sapiens_hsa047241.51555034
27Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.50399729
28Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.47165287
29Mineral absorption_Homo sapiens_hsa049781.46033133
30Oxidative phosphorylation_Homo sapiens_hsa001901.44262588
31Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.42038146
32Rheumatoid arthritis_Homo sapiens_hsa053231.41108382
33Collecting duct acid secretion_Homo sapiens_hsa049661.40196603
34Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.34095926
35Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.31457232
36Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.30606522
37Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.26425608
38Calcium signaling pathway_Homo sapiens_hsa040201.23152791
39GABAergic synapse_Homo sapiens_hsa047271.21945907
40Graft-versus-host disease_Homo sapiens_hsa053321.21833488
41Fanconi anemia pathway_Homo sapiens_hsa034601.21414356
42Linoleic acid metabolism_Homo sapiens_hsa005911.21338533
43Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.20270181
44Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.19039693
45SNARE interactions in vesicular transport_Homo sapiens_hsa041301.18842686
46Allograft rejection_Homo sapiens_hsa053301.17882888
47Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.16644890
48Circadian entrainment_Homo sapiens_hsa047131.13620708
49Peroxisome_Homo sapiens_hsa041461.13225823
50Steroid biosynthesis_Homo sapiens_hsa001001.11925624
51Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.11859041
52Ovarian steroidogenesis_Homo sapiens_hsa049131.11035701
53NF-kappa B signaling pathway_Homo sapiens_hsa040641.07462877
54Chemical carcinogenesis_Homo sapiens_hsa052041.06422274
55Proteasome_Homo sapiens_hsa030501.06310912
56Renin-angiotensin system_Homo sapiens_hsa046141.05143823
57alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.04781475
58* Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.04380000
59Primary immunodeficiency_Homo sapiens_hsa053401.03885873
60Type I diabetes mellitus_Homo sapiens_hsa049401.02167438
61Glycerolipid metabolism_Homo sapiens_hsa005611.01023744
62Intestinal immune network for IgA production_Homo sapiens_hsa046720.98701456
63Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.96623851
64Alzheimers disease_Homo sapiens_hsa050100.93976209
65Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.93721472
66Cysteine and methionine metabolism_Homo sapiens_hsa002700.92671229
67* Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.92318760
68Fatty acid elongation_Homo sapiens_hsa000620.91893721
69Hematopoietic cell lineage_Homo sapiens_hsa046400.91051974
70Fatty acid degradation_Homo sapiens_hsa000710.90593387
71Maturity onset diabetes of the young_Homo sapiens_hsa049500.88944834
72Circadian rhythm_Homo sapiens_hsa047100.88678530
73Salivary secretion_Homo sapiens_hsa049700.86270121
74Purine metabolism_Homo sapiens_hsa002300.85437204
75Homologous recombination_Homo sapiens_hsa034400.84187461
76Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.81367155
77Cardiac muscle contraction_Homo sapiens_hsa042600.81303747
78MAPK signaling pathway_Homo sapiens_hsa040100.78923047
79Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.78595018
80Lysine degradation_Homo sapiens_hsa003100.77268561
81Insulin secretion_Homo sapiens_hsa049110.77056348
82Caffeine metabolism_Homo sapiens_hsa002320.76994654
83Histidine metabolism_Homo sapiens_hsa003400.76952051
84Other glycan degradation_Homo sapiens_hsa005110.76516658
85Steroid hormone biosynthesis_Homo sapiens_hsa001400.75972581
86Ras signaling pathway_Homo sapiens_hsa040140.75472023
87Malaria_Homo sapiens_hsa051440.75402798
88Chemokine signaling pathway_Homo sapiens_hsa040620.73938951
89Long-term depression_Homo sapiens_hsa047300.73355446
90RNA degradation_Homo sapiens_hsa030180.73233983
91Parkinsons disease_Homo sapiens_hsa050120.73153815
92Retinol metabolism_Homo sapiens_hsa008300.73047168
93Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.72341409
94p53 signaling pathway_Homo sapiens_hsa041150.72260874
95Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.72201417
96Cholinergic synapse_Homo sapiens_hsa047250.71281629
97* beta-Alanine metabolism_Homo sapiens_hsa004100.70929617
98Asthma_Homo sapiens_hsa053100.69925655
99Synaptic vesicle cycle_Homo sapiens_hsa047210.69382546
100Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.68815149
101Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.67964656
102Selenocompound metabolism_Homo sapiens_hsa004500.66283369
103Vibrio cholerae infection_Homo sapiens_hsa051100.66101794
104Phagosome_Homo sapiens_hsa041450.66019966
105cAMP signaling pathway_Homo sapiens_hsa040240.65388367
106Toll-like receptor signaling pathway_Homo sapiens_hsa046200.65277074
107NOD-like receptor signaling pathway_Homo sapiens_hsa046210.64214547
108Renin secretion_Homo sapiens_hsa049240.61794298
109Vitamin digestion and absorption_Homo sapiens_hsa049770.60738286
110Dopaminergic synapse_Homo sapiens_hsa047280.59541647
111Pancreatic secretion_Homo sapiens_hsa049720.59423220
112B cell receptor signaling pathway_Homo sapiens_hsa046620.58653278
113Ribosome_Homo sapiens_hsa030100.57291136
114Basal transcription factors_Homo sapiens_hsa030220.57208393
115Starch and sucrose metabolism_Homo sapiens_hsa005000.57079466
116Vascular smooth muscle contraction_Homo sapiens_hsa042700.56476870
117Jak-STAT signaling pathway_Homo sapiens_hsa046300.56473444
118RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.55483941
119Fat digestion and absorption_Homo sapiens_hsa049750.55397706
120Hedgehog signaling pathway_Homo sapiens_hsa043400.54783150
121Dorso-ventral axis formation_Homo sapiens_hsa043200.52445208
122Regulation of autophagy_Homo sapiens_hsa041400.51833992
123Huntingtons disease_Homo sapiens_hsa050160.51448934
124Cocaine addiction_Homo sapiens_hsa050300.51349519
125Melanoma_Homo sapiens_hsa052180.51296700
126Oxytocin signaling pathway_Homo sapiens_hsa049210.51131687
127Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.50653838
128Dilated cardiomyopathy_Homo sapiens_hsa054140.49907191
129Wnt signaling pathway_Homo sapiens_hsa043100.49671372
130Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.48937883
131Nucleotide excision repair_Homo sapiens_hsa034200.48930259
132* Metabolic pathways_Homo sapiens_hsa011000.48838480
133Staphylococcus aureus infection_Homo sapiens_hsa051500.48228011
134Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.46658234
135Vitamin B6 metabolism_Homo sapiens_hsa007500.46055477
136Transcriptional misregulation in cancer_Homo sapiens_hsa052020.45742410
137Phosphatidylinositol signaling system_Homo sapiens_hsa040700.45715180
138Mismatch repair_Homo sapiens_hsa034300.44980875
139Measles_Homo sapiens_hsa051620.44737787
140ABC transporters_Homo sapiens_hsa020100.44603620
141Amphetamine addiction_Homo sapiens_hsa050310.44551348
142N-Glycan biosynthesis_Homo sapiens_hsa005100.44506405
143Glutathione metabolism_Homo sapiens_hsa004800.44234079
144cGMP-PKG signaling pathway_Homo sapiens_hsa040220.43222031
145Glycerophospholipid metabolism_Homo sapiens_hsa005640.42215648
146Tuberculosis_Homo sapiens_hsa051520.42068677
147Pyrimidine metabolism_Homo sapiens_hsa002400.40891520
148Protein export_Homo sapiens_hsa030600.40094023
149Gastric acid secretion_Homo sapiens_hsa049710.39335004
150T cell receptor signaling pathway_Homo sapiens_hsa046600.39032329
151Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.37574189
152Aldosterone synthesis and secretion_Homo sapiens_hsa049250.36677524
153Pyruvate metabolism_Homo sapiens_hsa006200.35847479

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