FSTL5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of chromatin binding (GO:0035561)7.27316265
2sensory perception of chemical stimulus (GO:0007606)7.26116876
3neuron cell-cell adhesion (GO:0007158)6.67238022
4adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)6.42233964
5protein localization to cilium (GO:0061512)5.53456059
6atrial cardiac muscle cell action potential (GO:0086014)5.46111490
7protein insertion into membrane (GO:0051205)5.31163609
8regulation of cilium movement (GO:0003352)5.07586707
9protein polyglutamylation (GO:0018095)5.07032126
10membrane depolarization during cardiac muscle cell action potential (GO:0086012)5.05189513
11axonal fasciculation (GO:0007413)5.03503234
12mating behavior (GO:0007617)4.54430278
13synaptic vesicle maturation (GO:0016188)4.52989715
14nucleobase catabolic process (GO:0046113)4.46752803
15intraciliary transport (GO:0042073)4.41341747
16presynaptic membrane organization (GO:0097090)4.35292652
17regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)4.32104618
18dendritic spine morphogenesis (GO:0060997)4.31059528
19neuron recognition (GO:0008038)4.28653481
20ganglion development (GO:0061548)4.27190101
21presynaptic membrane assembly (GO:0097105)4.26644959
22behavioral response to cocaine (GO:0048148)4.26229354
23regulation of heart rate by cardiac conduction (GO:0086091)4.22706760
24axoneme assembly (GO:0035082)4.16516683
25regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.10974104
26negative regulation of microtubule polymerization (GO:0031115)4.09679276
27ionotropic glutamate receptor signaling pathway (GO:0035235)4.05667086
28gamma-aminobutyric acid transport (GO:0015812)3.96448142
29synaptic vesicle docking involved in exocytosis (GO:0016081)3.95711257
30calcium-mediated signaling using intracellular calcium source (GO:0035584)3.88163776
31transmission of nerve impulse (GO:0019226)3.80951317
32epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.79773313
33cilium movement (GO:0003341)3.76215892
34neurotransmitter secretion (GO:0007269)3.71388232
35glutamate receptor signaling pathway (GO:0007215)3.68557773
36postsynaptic membrane organization (GO:0001941)3.67838222
37inositol phosphate catabolic process (GO:0071545)3.66860380
38auditory behavior (GO:0031223)3.66611584
39synaptic transmission, glutamatergic (GO:0035249)3.65164980
40membrane depolarization during action potential (GO:0086010)3.64570024
41G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.63229743
42neuronal action potential propagation (GO:0019227)3.60214261
43ER overload response (GO:0006983)3.59097195
44dopamine receptor signaling pathway (GO:0007212)3.58306572
45cellular response to prostaglandin stimulus (GO:0071379)3.57417454
46cilium morphogenesis (GO:0060271)3.54149007
47cardiac conduction (GO:0061337)3.53951719
48snRNA transcription (GO:0009301)3.53839484
49phosphorelay signal transduction system (GO:0000160)3.48448695
50synaptic vesicle exocytosis (GO:0016079)3.47852281
51response to auditory stimulus (GO:0010996)3.46890257
52negative regulation of axon extension involved in axon guidance (GO:0048843)3.46460575
53facial nerve structural organization (GO:0021612)3.44182976
54G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.44057676
55regulation of synapse structural plasticity (GO:0051823)3.44047055
56negative regulation of dendrite development (GO:2000171)3.43471282
57proline transport (GO:0015824)3.42032740
58neuron-neuron synaptic transmission (GO:0007270)3.42004650
59cellular response to glucagon stimulus (GO:0071377)3.41620624
60vocalization behavior (GO:0071625)3.40915753
61mitochondrion transport along microtubule (GO:0047497)3.39773410
62establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.39773410
63photoreceptor cell maintenance (GO:0045494)3.38527140
64auditory receptor cell differentiation (GO:0042491)3.38336254
65cellular copper ion homeostasis (GO:0006878)3.36445657
66brain morphogenesis (GO:0048854)3.33080131
67negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.31086883
68regulation of synaptic vesicle transport (GO:1902803)3.30974570
69negative regulation of cytosolic calcium ion concentration (GO:0051481)3.30896395
70neuronal ion channel clustering (GO:0045161)3.29914567
71retinal ganglion cell axon guidance (GO:0031290)3.29061660
72microtubule bundle formation (GO:0001578)3.29015309
73sensory perception of taste (GO:0050909)3.27452468
74inositol phosphate dephosphorylation (GO:0046855)3.27430877
75phosphorylated carbohydrate dephosphorylation (GO:0046838)3.27430877
76detection of calcium ion (GO:0005513)3.26556297
77axon extension (GO:0048675)3.23637219
78neuronal action potential (GO:0019228)3.23439587
79natural killer cell mediated cytotoxicity (GO:0042267)3.23169761
80natural killer cell mediated immunity (GO:0002228)3.23169761
81short-term memory (GO:0007614)3.22048949
82regulation of synaptic vesicle exocytosis (GO:2000300)3.20283249
83epithelial cilium movement (GO:0003351)3.20199686
84glutamate secretion (GO:0014047)3.19688185
85nonmotile primary cilium assembly (GO:0035058)3.15681301
86neurotransmitter-gated ion channel clustering (GO:0072578)3.14189695
87cerebellar Purkinje cell layer development (GO:0021680)3.13926651
88establishment of nucleus localization (GO:0040023)3.13037881
89adult walking behavior (GO:0007628)3.12729058
90layer formation in cerebral cortex (GO:0021819)3.12028630
91negative regulation of axon guidance (GO:1902668)3.11572706
92locomotory exploration behavior (GO:0035641)3.11408987
93cranial nerve structural organization (GO:0021604)3.09508999
94establishment of mitochondrion localization (GO:0051654)3.09472012
95positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.09022379
96neuron projection extension involved in neuron projection guidance (GO:1902284)3.07992875
97axon extension involved in axon guidance (GO:0048846)3.07992875
98regulation of microtubule-based movement (GO:0060632)3.07964619
99protein localization to synapse (GO:0035418)3.07193464
100synaptic vesicle endocytosis (GO:0048488)3.06390007
101regulation of postsynaptic membrane potential (GO:0060078)3.05412732
102gamma-aminobutyric acid signaling pathway (GO:0007214)3.05027672
103pyrimidine nucleobase catabolic process (GO:0006208)3.04993266
104central nervous system projection neuron axonogenesis (GO:0021952)3.04021702
105positive regulation of synapse maturation (GO:0090129)3.02702602
106exploration behavior (GO:0035640)3.02391814
107regulation of excitatory postsynaptic membrane potential (GO:0060079)3.01780283
108negative regulation of synaptic transmission, GABAergic (GO:0032229)3.00790125
109synapse organization (GO:0050808)2.99932712
110cilium assembly (GO:0042384)2.99657141
111regulation of cell communication by electrical coupling (GO:0010649)2.98760867
112dendrite morphogenesis (GO:0048813)2.98625063
113cellular potassium ion homeostasis (GO:0030007)2.98177003
114positive regulation of amino acid transport (GO:0051957)2.97639966
115positive regulation of membrane potential (GO:0045838)2.97239300
116membrane hyperpolarization (GO:0060081)2.95593598
117regulation of rhodopsin mediated signaling pathway (GO:0022400)2.95510207
118axonemal dynein complex assembly (GO:0070286)2.95414247
119neurotransmitter transport (GO:0006836)2.93303698
120regulation of sodium ion transmembrane transporter activity (GO:2000649)2.93010555
121regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.92998959
122regulation of short-term neuronal synaptic plasticity (GO:0048172)2.92288679
123regulation of neuronal synaptic plasticity (GO:0048168)2.91994667
124regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.90606341
125female mating behavior (GO:0060180)2.89838341
126positive regulation of dendritic spine morphogenesis (GO:0061003)2.88020401
127histone H2B ubiquitination (GO:0033523)2.87529009
128mechanosensory behavior (GO:0007638)2.87287878
129regulation of female receptivity (GO:0045924)2.86941268
130cerebellar Purkinje cell differentiation (GO:0021702)2.86891124
131regulation of synaptic transmission, glutamatergic (GO:0051966)2.85964270
132response to pheromone (GO:0019236)2.84711558
133multicellular organismal signaling (GO:0035637)2.84368899
134olfactory bulb development (GO:0021772)2.84308604
135negative regulation of transcription regulatory region DNA binding (GO:2000678)2.84305170
136positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.83659643
137hippocampus development (GO:0021766)2.83488950
138glycerophospholipid catabolic process (GO:0046475)2.82721377
139neurofilament cytoskeleton organization (GO:0060052)2.82530017
140neuron projection extension (GO:1990138)2.81494891
141adipose tissue development (GO:0060612)2.81447900
142regulation of neurotransmitter levels (GO:0001505)2.81378447
143calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.81048438
144cilium organization (GO:0044782)2.80566333
145regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.78576040
146glycosphingolipid biosynthetic process (GO:0006688)2.78359726
147regulation of neurotransmitter secretion (GO:0046928)2.76794461
148synapse assembly (GO:0007416)2.76198103
149dendrite development (GO:0016358)2.75714010
150rhodopsin mediated signaling pathway (GO:0016056)2.75686746
151regulation of long-term neuronal synaptic plasticity (GO:0048169)2.75333718
152calcium ion-dependent exocytosis (GO:0017156)2.75156671
153regulation of neurotransmitter transport (GO:0051588)2.75012635
154potassium ion homeostasis (GO:0055075)2.74900190
155membrane depolarization (GO:0051899)2.74735142
156regulation of vesicle fusion (GO:0031338)2.74579880
157adult behavior (GO:0030534)2.73150751
158positive regulation of synapse assembly (GO:0051965)2.73137210
159positive regulation of neurotransmitter transport (GO:0051590)2.73018061
160startle response (GO:0001964)2.72974191
161retinal cone cell development (GO:0046549)2.69976421
162behavioral fear response (GO:0001662)2.68567173
163behavioral defense response (GO:0002209)2.68567173
164central nervous system neuron axonogenesis (GO:0021955)2.68356183
165organelle transport along microtubule (GO:0072384)2.67720583
166negative regulation of axon extension (GO:0030517)2.64487333
167alanine transport (GO:0032328)2.63365985
168establishment of synaptic vesicle localization (GO:0097480)2.62804907
169sensory perception of smell (GO:0007608)10.9718407

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human7.91614291
2GBX2_23144817_ChIP-Seq_PC3_Human3.95408773
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.89062089
4ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.55641650
5BMI1_23680149_ChIP-Seq_NPCS_Mouse2.38852900
6* TAF15_26573619_Chip-Seq_HEK293_Human2.36471875
7FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.36378911
8JARID2_20064375_ChIP-Seq_MESCs_Mouse2.35919553
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.30537252
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.30537252
11SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.25628243
12PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human2.14157822
13EED_16625203_ChIP-ChIP_MESCs_Mouse2.10297080
14DROSHA_22980978_ChIP-Seq_HELA_Human2.07996061
15SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.05963959
16EZH2_27304074_Chip-Seq_ESCs_Mouse2.01717264
17SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.01610326
18JARID2_20075857_ChIP-Seq_MESCs_Mouse2.00237088
19SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.95522114
20AHR_22903824_ChIP-Seq_MCF-7_Human1.92868687
21SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.92091103
22* REST_21632747_ChIP-Seq_MESCs_Mouse1.89992436
23ZNF274_21170338_ChIP-Seq_K562_Hela1.84214938
24CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.82628305
25RBPJ_22232070_ChIP-Seq_NCS_Mouse1.81627104
26RNF2_27304074_Chip-Seq_ESCs_Mouse1.79336352
27MTF2_20144788_ChIP-Seq_MESCs_Mouse1.79102897
28BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.75382227
29P300_19829295_ChIP-Seq_ESCs_Human1.74139631
30SUZ12_27294783_Chip-Seq_ESCs_Mouse1.72737121
31* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.70866887
32TOP2B_26459242_ChIP-Seq_MCF-7_Human1.70318240
33SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.68568255
34EZH2_27294783_Chip-Seq_ESCs_Mouse1.66448652
35NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.66267575
36FUS_26573619_Chip-Seq_HEK293_Human1.65711397
37* SMAD4_21799915_ChIP-Seq_A2780_Human1.62119889
38* RNF2_27304074_Chip-Seq_NSC_Mouse1.61848505
39GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.61098689
40CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.59077108
41IKZF1_21737484_ChIP-ChIP_HCT116_Human1.55342641
42ARNT_22903824_ChIP-Seq_MCF-7_Human1.53609411
43CBX2_27304074_Chip-Seq_ESCs_Mouse1.52303554
44CTBP1_25329375_ChIP-Seq_LNCAP_Human1.51961289
45POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.46990140
46TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.46990140
47* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.46394997
48* REST_18959480_ChIP-ChIP_MESCs_Mouse1.45821633
49RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.42255325
50* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.41950445
51PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.40859511
52* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.39976005
53RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.34753412
54CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.34502512
55RARB_27405468_Chip-Seq_BRAIN_Mouse1.33573347
56EWS_26573619_Chip-Seq_HEK293_Human1.32356068
57SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.31581521
58AR_21572438_ChIP-Seq_LNCaP_Human1.31149769
59OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.30304617
60* RUNX2_22187159_ChIP-Seq_PCA_Human1.29578394
61ZNF263_19887448_ChIP-Seq_K562_Human1.27843605
62* SMAD3_21741376_ChIP-Seq_EPCs_Human1.27577278
63* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.26043024
64CTBP2_25329375_ChIP-Seq_LNCAP_Human1.23729022
65NANOG_18555785_Chip-Seq_ESCs_Mouse1.23165650
66TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.22114027
67* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.21661322
68SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21606197
69GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21185563
70PIAS1_25552417_ChIP-Seq_VCAP_Human1.20677857
71ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.19637182
72P53_22127205_ChIP-Seq_FIBROBLAST_Human1.17805504
73IGF1R_20145208_ChIP-Seq_DFB_Human1.15767284
74SMAD_19615063_ChIP-ChIP_OVARY_Human1.14750103
75RING1B_27294783_Chip-Seq_ESCs_Mouse1.13622079
76* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.13334028
77GATA1_26923725_Chip-Seq_HPCs_Mouse1.13215797
78* BCAT_22108803_ChIP-Seq_LS180_Human1.12951870
79* STAT3_23295773_ChIP-Seq_U87_Human1.08572538
80* SOX2_21211035_ChIP-Seq_LN229_Gbm1.07297548
81PRDM14_20953172_ChIP-Seq_ESCs_Human1.06806416
82LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06238569
83CBP_20019798_ChIP-Seq_JUKART_Human1.05755022
84IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.05755022
85YAP1_20516196_ChIP-Seq_MESCs_Mouse1.05532031
86NR3C1_23031785_ChIP-Seq_PC12_Mouse1.05395935
87TP53_18474530_ChIP-ChIP_U2OS_Human1.05334319
88MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.03665612
89* TCF4_23295773_ChIP-Seq_U87_Human1.03511408
90KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.03243513
91HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.00144336
92FLI1_21867929_ChIP-Seq_TH2_Mouse0.99226379
93AR_19668381_ChIP-Seq_PC3_Human0.97593725
94CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.96976254
95* P53_22387025_ChIP-Seq_ESCs_Mouse0.96852263
96SMAD4_21741376_ChIP-Seq_EPCs_Human0.96403407
97WT1_25993318_ChIP-Seq_PODOCYTE_Human0.96123141
98RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.95940339
99FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.94850038
100HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.94727146
101UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.94488287
102TAL1_26923725_Chip-Seq_HPCs_Mouse0.93324568
103RING1B_27294783_Chip-Seq_NPCs_Mouse0.92168378
104SOX9_26525672_Chip-Seq_HEART_Mouse0.92120462
105MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.91514875
106TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.91252787
107BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.90955124
108ER_23166858_ChIP-Seq_MCF-7_Human0.90920911
109EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.90405337
110AR_25329375_ChIP-Seq_VCAP_Human0.88874909
111TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88127390
112KDM2B_26808549_Chip-Seq_REH_Human0.87920466
113SMAD3_21741376_ChIP-Seq_ESCs_Human0.87358909
114* JUN_21703547_ChIP-Seq_K562_Human0.87089709
115CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.87065371
116RUNX1_27457419_Chip-Seq_LIVER_Mouse0.87012615
117* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.86581371
118CDX2_19796622_ChIP-Seq_MESCs_Mouse0.85720487
119VDR_22108803_ChIP-Seq_LS180_Human0.85425041
120RUNX1_26923725_Chip-Seq_HPCs_Mouse0.85087400

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001984_abnormal_olfaction8.61898371
2MP0008789_abnormal_olfactory_epithelium5.44425629
3MP0005499_abnormal_olfactory_system5.03827516
4MP0005394_taste/olfaction_phenotype5.03827516
5MP0005645_abnormal_hypothalamus_physiol3.97038380
6MP0004270_analgesia2.81721318
7MP0003122_maternal_imprinting2.63265920
8MP0002184_abnormal_innervation2.55698517
9MP0006276_abnormal_autonomic_nervous2.52606967
10MP0000372_irregular_coat_pigmentation2.38380902
11MP0002734_abnormal_mechanical_nocicepti2.36052904
12MP0003635_abnormal_synaptic_transmissio2.30497868
13MP0002160_abnormal_reproductive_system2.29362513
14MP0004859_abnormal_synaptic_plasticity2.12072157
15MP0002102_abnormal_ear_morphology2.10971923
16MP0003880_abnormal_central_pattern2.09622211
17MP0001485_abnormal_pinna_reflex2.02078401
18MP0009780_abnormal_chondrocyte_physiolo2.01393811
19MP0004858_abnormal_nervous_system1.99191459
20MP0002638_abnormal_pupillary_reflex1.96690111
21MP0000778_abnormal_nervous_system1.96672626
22MP0002557_abnormal_social/conspecific_i1.94511348
23MP0004742_abnormal_vestibular_system1.90883658
24MP0001486_abnormal_startle_reflex1.89751683
25MP0002063_abnormal_learning/memory/cond1.89006621
26MP0002272_abnormal_nervous_system1.87896553
27MP0005423_abnormal_somatic_nervous1.78840290
28MP0002822_catalepsy1.71932465
29MP0005551_abnormal_eye_electrophysiolog1.70529057
30MP0001542_abnormal_bone_strength1.64660155
31MP0002064_seizures1.64038485
32MP0002572_abnormal_emotion/affect_behav1.61918699
33MP0003121_genomic_imprinting1.61211890
34MP0009745_abnormal_behavioral_response1.57364270
35MP0002882_abnormal_neuron_morphology1.51296002
36MP0002067_abnormal_sensory_capabilities1.48307873
37MP0002752_abnormal_somatic_nervous1.47286465
38MP0001188_hyperpigmentation1.47007615
39MP0005646_abnormal_pituitary_gland1.46335623
40MP0003329_amyloid_beta_deposits1.44469457
41MP0002233_abnormal_nose_morphology1.42757230
42MP0009046_muscle_twitch1.40931171
43MP0001501_abnormal_sleep_pattern1.35582251
44MP0002837_dystrophic_cardiac_calcinosis1.34721388
45MP0001502_abnormal_circadian_rhythm1.33272428
46MP0002735_abnormal_chemical_nociception1.29698180
47MP0006072_abnormal_retinal_apoptosis1.23429781
48MP0005248_abnormal_Harderian_gland1.22266986
49MP0001529_abnormal_vocalization1.20994674
50MP0001968_abnormal_touch/_nociception1.20019840
51MP0004811_abnormal_neuron_physiology1.17757416
52MP0005174_abnormal_tail_pigmentation1.17614319
53MP0005389_reproductive_system_phenotype1.16827894
54MP0008877_abnormal_DNA_methylation1.16819088
55MP0002938_white_spotting1.15288122
56MP0003878_abnormal_ear_physiology1.13954685
57MP0005377_hearing/vestibular/ear_phenot1.13954685
58MP0002653_abnormal_ependyma_morphology1.11983597
59MP0000003_abnormal_adipose_tissue1.11145680
60MP0002152_abnormal_brain_morphology1.10367589
61MP0001970_abnormal_pain_threshold1.09151498
62MP0001963_abnormal_hearing_physiology1.06369714
63MP0003631_nervous_system_phenotype1.06292995
64MP0003787_abnormal_imprinting1.06034843
65MP0004133_heterotaxia1.05258977
66MP0002736_abnormal_nociception_after1.04252897
67MP0002229_neurodegeneration1.01368886
68MP0003136_yellow_coat_color1.01197614
69MP0005379_endocrine/exocrine_gland_phen1.00540528
70MP0003879_abnormal_hair_cell0.98684549
71MP0010386_abnormal_urinary_bladder0.98070780
72MP0000026_abnormal_inner_ear0.96273121
73MP0001944_abnormal_pancreas_morphology0.96237157
74MP0001293_anophthalmia0.95235651
75MP0002751_abnormal_autonomic_nervous0.93239665
76MP0004145_abnormal_muscle_electrophysio0.92131575
77MP0001986_abnormal_taste_sensitivity0.91110429
78MP0005171_absent_coat_pigmentation0.90477794
79MP0003890_abnormal_embryonic-extraembry0.90381403
80MP0003861_abnormal_nervous_system0.90116790
81MP0001299_abnormal_eye_distance/0.90106906
82MP0005386_behavior/neurological_phenoty0.88763898
83MP0004924_abnormal_behavior0.88763898
84MP0003632_abnormal_nervous_system0.85796961
85MP0000631_abnormal_neuroendocrine_gland0.85204990
86MP0002928_abnormal_bile_duct0.84634917
87MP0004885_abnormal_endolymph0.84549167
88MP0005195_abnormal_posterior_eye0.84191873
89MP0002090_abnormal_vision0.83239995
90MP0000566_synostosis0.81919809
91MP0002066_abnormal_motor_capabilities/c0.81335453
92MP0000955_abnormal_spinal_cord0.80945718
93MP0008995_early_reproductive_senescence0.80583857
94MP0003690_abnormal_glial_cell0.80361523
95MP0008569_lethality_at_weaning0.78552769
96MP0003806_abnormal_nucleotide_metabolis0.77517856
97MP0005535_abnormal_body_temperature0.73845474
98MP0000647_abnormal_sebaceous_gland0.73793511
99MP0005367_renal/urinary_system_phenotyp0.72726242
100MP0000516_abnormal_urinary_system0.72726242
101MP0003634_abnormal_glial_cell0.71997287
102MP0001440_abnormal_grooming_behavior0.71907793
103MP0003123_paternal_imprinting0.71434912
104MP0005084_abnormal_gallbladder_morpholo0.69341417
105MP0001905_abnormal_dopamine_level0.68957645
106MP0006292_abnormal_olfactory_placode0.67470977
107MP0002733_abnormal_thermal_nociception0.66979891
108MP0003183_abnormal_peptide_metabolism0.66567516
109MP0005623_abnormal_meninges_morphology0.66400091
110MP0000013_abnormal_adipose_tissue0.65610848
111MP0005410_abnormal_fertilization0.64988944
112MP0004085_abnormal_heartbeat0.64245543
113MP0002069_abnormal_eating/drinking_beha0.58713556
114MP0001324_abnormal_eye_pigmentation0.58434407
115MP0002909_abnormal_adrenal_gland0.58034257
116MP0005187_abnormal_penis_morphology0.54396755
117MP0008874_decreased_physiological_sensi0.53091672
118MP0000751_myopathy0.51346056
119MP0002132_abnormal_respiratory_system0.51332961
120MP0009703_decreased_birth_body0.49824914
121MP0002081_perinatal_lethality0.49766586
122MP0004142_abnormal_muscle_tone0.48814031
123MP0004134_abnormal_chest_morphology0.48239288
124MP0002082_postnatal_lethality0.47242657
125MP0010770_preweaning_lethality0.47242657
126MP0003633_abnormal_nervous_system0.46223518
127MP0003137_abnormal_impulse_conducting0.46106343
128MP0000569_abnormal_digit_pigmentation0.45865291
129MP0005253_abnormal_eye_physiology0.45799633
130MP0002896_abnormal_bone_mineralization0.45523707

Predicted human phenotypes

RankGene SetZ-score
1Hypothermia (HP:0002045)6.50010543
2Atonic seizures (HP:0010819)5.96419708
3Febrile seizures (HP:0002373)5.95563774
4Respiratory insufficiency due to defective ciliary clearance (HP:0200073)5.32498682
5Abnormal respiratory motile cilium physiology (HP:0012261)4.92206558
6Gait imbalance (HP:0002141)4.64258634
7Pancreatic fibrosis (HP:0100732)4.50282059
8Abnormal ciliary motility (HP:0012262)4.49514564
9Congenital primary aphakia (HP:0007707)4.39822220
10Nephrogenic diabetes insipidus (HP:0009806)4.21817917
11Abnormality of macular pigmentation (HP:0008002)4.20601072
12Medial flaring of the eyebrow (HP:0010747)4.17314507
13Absence seizures (HP:0002121)4.05941570
14Palpitations (HP:0001962)3.95127243
15Polyphagia (HP:0002591)3.94031798
16Molar tooth sign on MRI (HP:0002419)3.91835294
17Abnormality of midbrain morphology (HP:0002418)3.91835294
18Rhinitis (HP:0012384)3.81239196
19Focal seizures (HP:0007359)3.78426618
20Abnormal respiratory epithelium morphology (HP:0012253)3.78091297
21Abnormal respiratory motile cilium morphology (HP:0005938)3.78091297
22Retinal dysplasia (HP:0007973)3.73324132
23Limb dystonia (HP:0002451)3.69891383
24Anosmia (HP:0000458)3.68992897
25Hemiparesis (HP:0001269)3.67872709
26Poor coordination (HP:0002370)3.63815912
27Genital tract atresia (HP:0001827)3.60820220
28Abnormality of the corticospinal tract (HP:0002492)3.55680057
29Intestinal atresia (HP:0011100)3.50843803
30Dialeptic seizures (HP:0011146)3.45166751
31Vaginal atresia (HP:0000148)3.38054208
32Chronic hepatic failure (HP:0100626)3.34274802
33Abnormal eating behavior (HP:0100738)3.24334173
34Degeneration of the lateral corticospinal tracts (HP:0002314)3.17052465
35Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.17052465
36Aqueductal stenosis (HP:0002410)3.12789015
37Postaxial hand polydactyly (HP:0001162)3.09851045
38True hermaphroditism (HP:0010459)3.09746015
39Drooling (HP:0002307)3.04553643
40Generalized tonic-clonic seizures (HP:0002069)2.99155766
41Central scotoma (HP:0000603)2.96481868
42Nephronophthisis (HP:0000090)2.88076846
43Congenital malformation of the right heart (HP:0011723)2.88028765
44Double outlet right ventricle (HP:0001719)2.88028765
45Bradycardia (HP:0001662)2.83917057
46Excessive salivation (HP:0003781)2.78914461
47Aplasia/Hypoplasia of the lens (HP:0008063)2.78857112
48Xerostomia (HP:0000217)2.76272785
49Agitation (HP:0000713)2.75605416
50Broad-based gait (HP:0002136)2.75056933
51Chronic bronchitis (HP:0004469)2.69788865
52Urinary urgency (HP:0000012)2.68200806
53Spastic gait (HP:0002064)2.64424107
54Bony spicule pigmentary retinopathy (HP:0007737)2.63150090
55Absent/shortened dynein arms (HP:0200106)2.63103682
56Dynein arm defect of respiratory motile cilia (HP:0012255)2.63103682
57Gaze-evoked nystagmus (HP:0000640)2.62444232
58Progressive cerebellar ataxia (HP:0002073)2.60970722
59Focal motor seizures (HP:0011153)2.60068305
60Aplasia/Hypoplasia of the tongue (HP:0010295)2.59484145
61Impaired vibration sensation in the lower limbs (HP:0002166)2.58112120
62Occipital encephalocele (HP:0002085)2.56672354
63Epileptiform EEG discharges (HP:0011182)2.56444193
64Intention tremor (HP:0002080)2.56307459
65EEG with generalized epileptiform discharges (HP:0011198)2.50035322
66Amblyopia (HP:0000646)2.49516472
67Bifid tongue (HP:0010297)2.48669157
68Complete atrioventricular canal defect (HP:0001674)2.48547884
69Abnormality of dentin (HP:0010299)2.47572105
70Visual hallucinations (HP:0002367)2.46850768
71Median cleft lip (HP:0000161)2.46848727
72Morphological abnormality of the pyramidal tract (HP:0002062)2.46700388
73Hyperventilation (HP:0002883)2.45771006
74Postaxial foot polydactyly (HP:0001830)2.45256131
75Hypsarrhythmia (HP:0002521)2.44973100
76Myokymia (HP:0002411)2.44896203
77Urinary bladder sphincter dysfunction (HP:0002839)2.34823288
78Impaired pain sensation (HP:0007328)2.34582258
79Abnormality of pain sensation (HP:0010832)2.34582258
80Sleep apnea (HP:0010535)2.34376617
81Specific learning disability (HP:0001328)2.33695001
82Syncope (HP:0001279)2.33619438
83Supranuclear gaze palsy (HP:0000605)2.31883575
84Abnormal EKG (HP:0003115)2.31843639
85Pheochromocytoma (HP:0002666)2.30707795
86Epileptic encephalopathy (HP:0200134)2.30448674
87Oligodactyly (hands) (HP:0001180)2.29218781
88Pancreatic cysts (HP:0001737)2.27763014
89Fetal akinesia sequence (HP:0001989)2.26710002
90Oculomotor apraxia (HP:0000657)2.25164186
91Amyotrophic lateral sclerosis (HP:0007354)2.23755689
92Abnormality of the renal medulla (HP:0100957)2.23711443
93Spastic tetraplegia (HP:0002510)2.22406755
94Hypochromic microcytic anemia (HP:0004840)2.20547454
95Ankle clonus (HP:0011448)2.20336227
96Dysdiadochokinesis (HP:0002075)2.19802041
97Failure to thrive in infancy (HP:0001531)2.19112603
98Congenital stationary night blindness (HP:0007642)2.18426306
99Gastrointestinal atresia (HP:0002589)2.17556060
100Abolished electroretinogram (ERG) (HP:0000550)2.16090070
101Prolonged QT interval (HP:0001657)2.15361683
102Short tibia (HP:0005736)2.14548217
103Akinesia (HP:0002304)2.14325110
104Cystic liver disease (HP:0006706)2.13164036
105Pachygyria (HP:0001302)2.12685645
106Action tremor (HP:0002345)2.11273962
107Absent speech (HP:0001344)2.10572557
108Exotropia (HP:0000577)2.10241185
109Labial hypoplasia (HP:0000066)2.08633151
110Tubulointerstitial nephritis (HP:0001970)2.08285792
111Lissencephaly (HP:0001339)2.07743513
112Abnormality of the labia minora (HP:0012880)2.07344907
113Poor suck (HP:0002033)2.06119323
114Primary atrial arrhythmia (HP:0001692)2.02645294
115Aplasia/Hypoplasia of the brainstem (HP:0007362)2.01275970
116Hypoplasia of the brainstem (HP:0002365)2.01275970
117Abnormal rod and cone electroretinograms (HP:0008323)2.01272345
118Genetic anticipation (HP:0003743)2.00147316
119Intellectual disability, moderate (HP:0002342)1.98779889
120Ulnar claw (HP:0001178)1.97468058
121Retinitis pigmentosa (HP:0000510)1.97415337
122Abnormality of binocular vision (HP:0011514)1.97156603
123Diplopia (HP:0000651)1.97156603
124Abnormality of salivation (HP:0100755)1.97047677
125Aplasia/Hypoplasia of the tibia (HP:0005772)1.95575526
126Atrioventricular canal defect (HP:0006695)1.94216219
127Left ventricular hypertrophy (HP:0001712)1.93093605
128Status epilepticus (HP:0002133)1.92564140
129Muscular hypotonia of the trunk (HP:0008936)1.92218886
130Megalencephaly (HP:0001355)1.92030726
131Abnormality of the lower motor neuron (HP:0002366)1.91652557
132Decreased central vision (HP:0007663)1.89919662
133Neuroendocrine neoplasm (HP:0100634)1.89072245
134Supraventricular tachycardia (HP:0004755)1.88671571
135Postural tremor (HP:0002174)1.88662087
136Decreased testicular size (HP:0008734)1.87765055
137Truncal ataxia (HP:0002078)1.87281748
138Anxiety (HP:0000739)1.87202102
139Congenital hepatic fibrosis (HP:0002612)1.87145852
140Lower limb muscle weakness (HP:0007340)1.86699944
141Dyschromatopsia (HP:0007641)1.85942627
142Severe visual impairment (HP:0001141)1.84980521
143Dysphonia (HP:0001618)1.83849340
144Esophageal atresia (HP:0002032)1.83657554
145Paraplegia (HP:0010550)1.82159472
146Hypoplastic female external genitalia (HP:0012815)1.81866956
147Supraventricular arrhythmia (HP:0005115)1.80363776
148Abnormal hair whorl (HP:0010721)1.79358059
149Constricted visual fields (HP:0001133)1.78972550
150Depression (HP:0000716)1.77819074
151Neurofibrillary tangles (HP:0002185)1.76971464
152Mutism (HP:0002300)1.76138590
153Scotoma (HP:0000575)1.75797660
154Impaired vibratory sensation (HP:0002495)1.75492576
155Postural instability (HP:0002172)1.74458491
156Sclerocornea (HP:0000647)1.73526984
157Bronchiectasis (HP:0002110)1.73391229
158Abnormality of the parathyroid morphology (HP:0011766)1.72496617
159Aganglionic megacolon (HP:0002251)1.72433689
160Asthma (HP:0002099)1.72297407
161Preaxial hand polydactyly (HP:0001177)1.72236216
162Optic nerve hypoplasia (HP:0000609)1.71651655
163Cortical dysplasia (HP:0002539)1.71419638
164Male pseudohermaphroditism (HP:0000037)1.71173770
165Broad foot (HP:0001769)1.70497246
166Absent eyebrow (HP:0002223)1.70441018
167Torticollis (HP:0000473)1.69615910

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERBB34.01804384
2CASK3.26879221
3MARK13.23109879
4PRPF4B3.18583701
5WNK33.12012850
6MAP2K72.96359621
7NTRK22.89837197
8MAPK132.85535570
9PINK12.84824767
10PHKG22.82323161
11PHKG12.82323161
12DAPK22.66527252
13MINK12.41666052
14ARAF2.32429389
15MAP3K42.30303533
16BMPR22.18370120
17AKT32.06814856
18EEF2K1.93948644
19MAPK151.91536715
20TRIM281.83784310
21EPHA31.79877435
22SRPK11.79052775
23FGFR21.78414364
24STK241.76415712
25MAP2K41.75078408
26MAPKAPK31.72598267
27MAP3K121.55477061
28CAMK2B1.50568471
29CSNK1A1L1.45668702
30NTRK31.43066019
31SGK4941.39596872
32SGK2231.39596872
33CAMK2D1.38008922
34TAOK11.37394211
35SIK31.36367040
36SIK21.34153535
37SGK21.30671668
38DAPK11.25754629
39BRAF1.24629962
40STK38L1.23738095
41PLK21.22467574
42DYRK31.21782277
43CSNK1G31.15885275
44DYRK1A1.14303574
45PAK31.13906309
46CSNK1G21.12674059
47PRKCG1.11788745
48RIPK11.08970199
49UHMK11.05050103
50CDK191.00941563
51CAMK2G0.99024065
52RPS6KA20.94669424
53MAP4K20.92535235
54STK390.90630436
55MAP3K60.89554248
56HIPK20.88690799
57DYRK20.83121915
58TNIK0.81538399
59CDK50.80579205
60SGK30.80170979
61CAMKK10.80043060
62CSNK1G10.79606022
63CAMK2A0.75522126
64TNK20.74616430
65GRK50.73029122
66CAMK1G0.73026039
67CAMKK20.69409961
68LIMK10.67702111
69GRK10.67048884
70ADRBK20.66541306
71PRKCZ0.66148343
72INSRR0.65780624
73PRKD30.64127532
74STK110.63676081
75PIM20.63293386
76PRKCE0.62308242
77PNCK0.60880414
78STK160.60115583
79ICK0.56789265
80PAK60.54557440
81WNK10.53823569
82MAPKAPK50.52318267
83PKN10.51946991
84CDK150.50098304
85CSNK1D0.49677309
86RPS6KB10.49360832
87EPHA40.49139087
88SGK10.48985007
89CAMK40.48339927
90PRKAA10.47845675
91CAMK10.45880870
92CSNK1A10.45730109
93FER0.45392891
94GRK70.44019582
95PLK40.43821587
96CSNK1E0.43779749
97PRKCB0.42512121
98YES10.42081363
99MARK20.42066924
100ROCK20.41994957
101CDK11A0.41822825
102RPS6KA30.41007391
103ERBB20.38362667
104FRK0.37545312
105LMTK20.37498220
106CAMK1D0.37183426
107DAPK30.36526909
108BCR0.35316168
109PRKACB0.35206520
110TRPM70.35124552
111MAP3K20.35024665
112MAPK90.34624917
113MAPK80.34606668
114MAP3K90.32975597
115WNK40.32890855
116PRKG10.32776069
117PRKCA0.31077680
118TYRO30.31062328
119CDK30.30510538
120NUAK10.30263533
121PRKCH0.29968180
122TESK10.29826015
123AURKA0.29818425
124ADRBK10.28839468
125OXSR10.28527030
126CDK180.27979889
127STK380.27874847
128MAPK100.26924804
129PRKACA0.26820318
130KSR10.26583777
131FYN0.26212798
132MKNK20.26212096
133DYRK1B0.26121619
134NTRK10.26093172
135CDK140.24656388

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047408.18257081
2Phototransduction_Homo sapiens_hsa047443.73811317
3Synaptic vesicle cycle_Homo sapiens_hsa047213.01498539
4Morphine addiction_Homo sapiens_hsa050322.72187944
5GABAergic synapse_Homo sapiens_hsa047272.68334517
6Taste transduction_Homo sapiens_hsa047422.59076544
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.56542028
8Circadian entrainment_Homo sapiens_hsa047132.49760636
9Dopaminergic synapse_Homo sapiens_hsa047282.32505357
10Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.26053064
11Maturity onset diabetes of the young_Homo sapiens_hsa049502.24540227
12Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.21451589
13Nicotine addiction_Homo sapiens_hsa050332.21441131
14Glutamatergic synapse_Homo sapiens_hsa047242.21352853
15Serotonergic synapse_Homo sapiens_hsa047262.08614649
16Cholinergic synapse_Homo sapiens_hsa047251.93502613
17Insulin secretion_Homo sapiens_hsa049111.79062541
18Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.77056933
19Collecting duct acid secretion_Homo sapiens_hsa049661.76656180
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.60038753
21Amphetamine addiction_Homo sapiens_hsa050311.46983364
22Vibrio cholerae infection_Homo sapiens_hsa051101.36355001
23Salivary secretion_Homo sapiens_hsa049701.34121804
24Long-term potentiation_Homo sapiens_hsa047201.32681202
25Aldosterone synthesis and secretion_Homo sapiens_hsa049251.28891103
26Alcoholism_Homo sapiens_hsa050341.23655160
27Gastric acid secretion_Homo sapiens_hsa049711.23431335
28Vitamin B6 metabolism_Homo sapiens_hsa007501.22506433
29Renin secretion_Homo sapiens_hsa049241.15646449
30Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.11327868
31Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.10212829
32Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.10071940
33Axon guidance_Homo sapiens_hsa043601.09096377
34Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.07971582
35Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.07031519
36Calcium signaling pathway_Homo sapiens_hsa040201.06485727
37Circadian rhythm_Homo sapiens_hsa047101.05125896
38SNARE interactions in vesicular transport_Homo sapiens_hsa041301.02558413
39Butanoate metabolism_Homo sapiens_hsa006501.02090798
40cAMP signaling pathway_Homo sapiens_hsa040241.01890528
41Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.01774705
42Protein export_Homo sapiens_hsa030601.01104791
43GnRH signaling pathway_Homo sapiens_hsa049120.95907096
44cGMP-PKG signaling pathway_Homo sapiens_hsa040220.89191386
45Alzheimers disease_Homo sapiens_hsa050100.89154403
46Oxytocin signaling pathway_Homo sapiens_hsa049210.87842811
47Phosphatidylinositol signaling system_Homo sapiens_hsa040700.85575571
48Steroid biosynthesis_Homo sapiens_hsa001000.83629849
49Oxidative phosphorylation_Homo sapiens_hsa001900.83220293
50Parkinsons disease_Homo sapiens_hsa050120.83183586
51Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.80400127
52Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.79775133
53Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.79119347
54Gap junction_Homo sapiens_hsa045400.77597839
55Fatty acid elongation_Homo sapiens_hsa000620.74562405
56Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.74073921
57Ovarian steroidogenesis_Homo sapiens_hsa049130.73780805
58Melanogenesis_Homo sapiens_hsa049160.72150938
59Fatty acid biosynthesis_Homo sapiens_hsa000610.70426146
60Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.68037989
61Carbohydrate digestion and absorption_Homo sapiens_hsa049730.67504511
62Estrogen signaling pathway_Homo sapiens_hsa049150.66886769
63ErbB signaling pathway_Homo sapiens_hsa040120.66882385
64Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.66656706
65Cardiac muscle contraction_Homo sapiens_hsa042600.64491493
66Endometrial cancer_Homo sapiens_hsa052130.63994284
67Cocaine addiction_Homo sapiens_hsa050300.63925299
68Glioma_Homo sapiens_hsa052140.62036808
69Ras signaling pathway_Homo sapiens_hsa040140.61794371
70Glucagon signaling pathway_Homo sapiens_hsa049220.60905629
71Long-term depression_Homo sapiens_hsa047300.60219014
72Oocyte meiosis_Homo sapiens_hsa041140.56330789
73Prion diseases_Homo sapiens_hsa050200.56050480
74Thyroid hormone synthesis_Homo sapiens_hsa049180.54662674
75Vascular smooth muscle contraction_Homo sapiens_hsa042700.54116074
76Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.51817639
77Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.51389897
78Huntingtons disease_Homo sapiens_hsa050160.51240608
79beta-Alanine metabolism_Homo sapiens_hsa004100.50622827
80Colorectal cancer_Homo sapiens_hsa052100.50489449
81Dorso-ventral axis formation_Homo sapiens_hsa043200.48567327
82Insulin signaling pathway_Homo sapiens_hsa049100.47954087
83Type II diabetes mellitus_Homo sapiens_hsa049300.46547679
84Neurotrophin signaling pathway_Homo sapiens_hsa047220.45519885
85Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.42550420
86Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.42106688
87MAPK signaling pathway_Homo sapiens_hsa040100.41495867
88Sphingolipid metabolism_Homo sapiens_hsa006000.40958593
89Dilated cardiomyopathy_Homo sapiens_hsa054140.40273286
90Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.39621738
91Chemokine signaling pathway_Homo sapiens_hsa040620.39428030
92Folate biosynthesis_Homo sapiens_hsa007900.39319953
93Bile secretion_Homo sapiens_hsa049760.38990433
94Histidine metabolism_Homo sapiens_hsa003400.38888917
95Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.37749950
96Regulation of autophagy_Homo sapiens_hsa041400.37142949
97Hedgehog signaling pathway_Homo sapiens_hsa043400.36779949
98Pyruvate metabolism_Homo sapiens_hsa006200.34903503
99Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.33044927
100Propanoate metabolism_Homo sapiens_hsa006400.32508896
101Hepatitis C_Homo sapiens_hsa051600.32305201
102Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.31490229
103Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.31052640
104Fatty acid metabolism_Homo sapiens_hsa012120.30923305
105Peroxisome_Homo sapiens_hsa041460.30908376
106Pancreatic secretion_Homo sapiens_hsa049720.29140451
107Hippo signaling pathway_Homo sapiens_hsa043900.29135768
108Linoleic acid metabolism_Homo sapiens_hsa005910.28127460
109Inositol phosphate metabolism_Homo sapiens_hsa005620.28107560
110Tight junction_Homo sapiens_hsa045300.28005944
111Phagosome_Homo sapiens_hsa041450.26827894
112Arginine and proline metabolism_Homo sapiens_hsa003300.26745024
113ABC transporters_Homo sapiens_hsa020100.25145710
114Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.23671986
115Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.23597779
116Rheumatoid arthritis_Homo sapiens_hsa053230.22725446
117Steroid hormone biosynthesis_Homo sapiens_hsa001400.22030387
118Melanoma_Homo sapiens_hsa052180.21088840
119Ether lipid metabolism_Homo sapiens_hsa005650.20700191
120Sphingolipid signaling pathway_Homo sapiens_hsa040710.19253673
121Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.17606286
122Rap1 signaling pathway_Homo sapiens_hsa040150.17123838
123Sulfur relay system_Homo sapiens_hsa041220.16965093
124Longevity regulating pathway - mammal_Homo sapiens_hsa042110.15923195
125Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.15194645

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