FSBP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein localization to kinetochore (GO:0034501)5.90828945
2mitotic metaphase plate congression (GO:0007080)5.56187878
3protein localization to chromosome, centromeric region (GO:0071459)5.30501251
4kinetochore organization (GO:0051383)5.24252741
5mitotic chromosome condensation (GO:0007076)5.18090619
6DNA replication checkpoint (GO:0000076)5.17206971
7DNA strand elongation involved in DNA replication (GO:0006271)5.16693763
8telomere maintenance via semi-conservative replication (GO:0032201)5.03328088
9DNA unwinding involved in DNA replication (GO:0006268)5.02989640
10attachment of spindle microtubules to kinetochore (GO:0008608)5.01808060
11mitotic recombination (GO:0006312)4.96350587
12metaphase plate congression (GO:0051310)4.91698816
13CENP-A containing nucleosome assembly (GO:0034080)4.88053826
14regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.87691550
15DNA strand elongation (GO:0022616)4.86816764
16chromatin remodeling at centromere (GO:0031055)4.78277870
17regulation of spindle organization (GO:0090224)4.77362184
18telomere maintenance via recombination (GO:0000722)4.76663133
19kinetochore assembly (GO:0051382)4.65086675
20mitotic sister chromatid segregation (GO:0000070)4.47429597
21establishment of chromosome localization (GO:0051303)4.43884060
22DNA replication initiation (GO:0006270)4.40041460
23regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)4.33253277
24otic vesicle formation (GO:0030916)4.31824263
25sister chromatid segregation (GO:0000819)4.31171539
26meiotic chromosome segregation (GO:0045132)4.29611300
27DNA replication-independent nucleosome assembly (GO:0006336)4.22806993
28DNA replication-independent nucleosome organization (GO:0034724)4.22806993
29regulation of nuclear cell cycle DNA replication (GO:0033262)4.19569027
30regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.12141566
31histone exchange (GO:0043486)4.09388800
32telomere maintenance via telomere lengthening (GO:0010833)4.02904052
33nuclear pore organization (GO:0006999)4.01677411
34regulation of double-strand break repair via homologous recombination (GO:0010569)3.92187776
35mitotic sister chromatid cohesion (GO:0007064)3.91542251
36spindle checkpoint (GO:0031577)3.82890946
37regulation of mitotic spindle organization (GO:0060236)3.78915842
38mitotic nuclear envelope disassembly (GO:0007077)3.77303438
39DNA topological change (GO:0006265)3.76401627
40limb bud formation (GO:0060174)3.74683558
41nucleotide-excision repair, DNA gap filling (GO:0006297)3.74417506
42DNA replication-dependent nucleosome assembly (GO:0006335)3.70964989
43DNA replication-dependent nucleosome organization (GO:0034723)3.70964989
44presynaptic membrane assembly (GO:0097105)3.70106677
45nucleobase biosynthetic process (GO:0046112)3.69677256
46protein localization to chromosome (GO:0034502)3.66553143
47somatic hypermutation of immunoglobulin genes (GO:0016446)3.65451967
48somatic diversification of immune receptors via somatic mutation (GO:0002566)3.65451967
49positive regulation of chromosome segregation (GO:0051984)3.61804433
50nuclear pore complex assembly (GO:0051292)3.58846923
51regulation of centriole replication (GO:0046599)3.57258111
52negative regulation of translation, ncRNA-mediated (GO:0040033)3.55565114
53regulation of translation, ncRNA-mediated (GO:0045974)3.55565114
54negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.55565114
55translesion synthesis (GO:0019985)3.52250179
56purine nucleobase biosynthetic process (GO:0009113)3.50603462
57mismatch repair (GO:0006298)3.49888866
58chromosome segregation (GO:0007059)3.49399682
59regulation of mitotic metaphase/anaphase transition (GO:0030071)3.48188261
60regulation of chromosome segregation (GO:0051983)3.47430682
61spindle assembly checkpoint (GO:0071173)3.46244272
62membrane disassembly (GO:0030397)3.45144800
63nuclear envelope disassembly (GO:0051081)3.45144800
64negative regulation of chromosome segregation (GO:0051985)3.43947293
65regulation of mitotic spindle checkpoint (GO:1903504)3.40955955
66regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.40955955
67negative regulation of mitotic sister chromatid separation (GO:2000816)3.40329009
68negative regulation of mitotic sister chromatid segregation (GO:0033048)3.40329009
69negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.40329009
70negative regulation of sister chromatid segregation (GO:0033046)3.40329009
71maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.39786479
72regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.39174176
73regulation of centrosome cycle (GO:0046605)3.39044053
74DNA geometric change (GO:0032392)3.38535360
75DNA duplex unwinding (GO:0032508)3.36844610
76chromosome condensation (GO:0030261)3.30944225
77chromatin assembly or disassembly (GO:0006333)3.30108934
78negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.28894876
79microtubule depolymerization (GO:0007019)3.28541978
80mitotic spindle assembly checkpoint (GO:0007094)3.27558071
81ATP-dependent chromatin remodeling (GO:0043044)3.26765226
82mitotic spindle checkpoint (GO:0071174)3.24904529
83regulation of sister chromatid segregation (GO:0033045)3.22481243
84regulation of mitotic sister chromatid separation (GO:0010965)3.22481243
85regulation of mitotic sister chromatid segregation (GO:0033047)3.22481243
86regulation of helicase activity (GO:0051095)3.20267890
87negative regulation of histone methylation (GO:0031061)3.18653815
88replication fork processing (GO:0031297)3.17971369
89DNA double-strand break processing (GO:0000729)3.17650625
90regulation of sister chromatid cohesion (GO:0007063)3.15490384
91telomere maintenance (GO:0000723)3.14538349
92histone-serine phosphorylation (GO:0035404)3.13099805
93resolution of meiotic recombination intermediates (GO:0000712)3.11578266
94telomere organization (GO:0032200)3.10156831
95negative regulation of DNA-dependent DNA replication (GO:2000104)3.09607674
96DNA conformation change (GO:0071103)3.09532065
97regulation of cilium movement (GO:0003352)3.07589558
98postreplication repair (GO:0006301)3.05958789
99prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060523.05264624
100IMP biosynthetic process (GO:0006188)3.03357973
101positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.03333674
102positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.03333674
103positive regulation of mitotic sister chromatid separation (GO:1901970)3.03333674
104ribosome assembly (GO:0042255)3.03176221
105regulation of double-strand break repair (GO:2000779)3.02217459
106mitotic cell cycle (GO:0000278)3.01056573
107regulation of telomere maintenance via telomerase (GO:0032210)2.99743007
108pore complex assembly (GO:0046931)2.99657006
109protein prenylation (GO:0018342)2.99603176
110prenylation (GO:0097354)2.99603176
111base-excision repair (GO:0006284)2.98693497
112protein K6-linked ubiquitination (GO:0085020)2.98279743
113presynaptic membrane organization (GO:0097090)2.97858236
114RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.94613784
115retinal cone cell development (GO:0046549)2.93784087
116establishment of integrated proviral latency (GO:0075713)2.91253110
117DNA damage response, detection of DNA damage (GO:0042769)2.88415971
118DNA ligation (GO:0006266)2.88149267
119cullin deneddylation (GO:0010388)2.87876275
120exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.83029552
121nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.82244587
122histone mRNA metabolic process (GO:0008334)2.80066536
123protein deneddylation (GO:0000338)2.76538189
124lactate metabolic process (GO:0006089)2.74563139
125L-serine metabolic process (GO:0006563)2.74285016
126pre-miRNA processing (GO:0031054)2.70035782
127lung-associated mesenchyme development (GO:0060484)2.68761287
128termination of RNA polymerase III transcription (GO:0006386)2.64079185
129transcription elongation from RNA polymerase III promoter (GO:0006385)2.64079185
130negative regulation of DNA recombination (GO:0045910)2.63818257
131dorsal/ventral axis specification (GO:0009950)2.63628364
132branched-chain amino acid catabolic process (GO:0009083)2.60479674
133double-strand break repair via nonhomologous end joining (GO:0006303)2.60154632
134non-recombinational repair (GO:0000726)2.60154632
135somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.59887537
136somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.59887537
137isotype switching (GO:0045190)2.59887537
138response to pheromone (GO:0019236)2.59712254
139digestive tract morphogenesis (GO:0048546)2.59122203
140DNA catabolic process, exonucleolytic (GO:0000738)2.58567565
141response to X-ray (GO:0010165)2.58249928
142retinal rod cell development (GO:0046548)2.58001474
143protein neddylation (GO:0045116)2.56714195
144intraciliary transport (GO:0042073)2.56575871
145organelle disassembly (GO:1903008)2.53973297
146peptidyl-histidine modification (GO:0018202)2.52809746
147reciprocal DNA recombination (GO:0035825)2.51225815
148reciprocal meiotic recombination (GO:0007131)2.51225815
149transcription elongation from RNA polymerase I promoter (GO:0006362)2.50329668
150spliceosomal snRNP assembly (GO:0000387)2.50287786
151recombinational repair (GO:0000725)2.47717653
152mitochondrial RNA metabolic process (GO:0000959)2.47102934
153C4-dicarboxylate transport (GO:0015740)2.47067335
154mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.46414853
155mitochondrial respiratory chain complex I assembly (GO:0032981)2.46414853
156NADH dehydrogenase complex assembly (GO:0010257)2.46414853
157double-strand break repair via homologous recombination (GO:0000724)2.45933516
158cilium morphogenesis (GO:0060271)2.45528878
1597-methylguanosine mRNA capping (GO:0006370)2.44755878
160eye photoreceptor cell development (GO:0042462)2.43585580

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human6.24449784
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.81484875
3FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.88234322
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.76138892
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.94553422
6FUS_26573619_Chip-Seq_HEK293_Human2.71726419
7MYC_19079543_ChIP-ChIP_MESCs_Mouse2.71277583
8AR_21909140_ChIP-Seq_LNCAP_Human2.69838730
9POU3F2_20337985_ChIP-ChIP_501MEL_Human2.64953819
10EGR1_19374776_ChIP-ChIP_THP-1_Human2.63385267
11MYC_19030024_ChIP-ChIP_MESCs_Mouse2.55431088
12EWS_26573619_Chip-Seq_HEK293_Human2.53746257
13EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.47080368
14TAF15_26573619_Chip-Seq_HEK293_Human2.45162273
15EST1_17652178_ChIP-ChIP_JURKAT_Human2.43234015
16GBX2_23144817_ChIP-Seq_PC3_Human2.43151330
17ZNF274_21170338_ChIP-Seq_K562_Hela2.37622156
18MYC_18358816_ChIP-ChIP_MESCs_Mouse2.34282483
19E2F1_21310950_ChIP-Seq_MCF-7_Human2.33476619
20KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.32196666
21GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.30857619
22CREB1_15753290_ChIP-ChIP_HEK293T_Human2.30474011
23CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.27805506
24MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.25572673
25VDR_22108803_ChIP-Seq_LS180_Human2.25062325
26NELFA_20434984_ChIP-Seq_ESCs_Mouse2.17668415
27E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.16835230
28IGF1R_20145208_ChIP-Seq_DFB_Human2.16346847
29ZFP57_27257070_Chip-Seq_ESCs_Mouse2.15209388
30ETS1_20019798_ChIP-Seq_JURKAT_Human2.14023691
31FLI1_27457419_Chip-Seq_LIVER_Mouse2.10173899
32P300_19829295_ChIP-Seq_ESCs_Human2.08821610
33CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.08034803
34GABP_17652178_ChIP-ChIP_JURKAT_Human2.06669198
35XRN2_22483619_ChIP-Seq_HELA_Human2.03530717
36SALL1_21062744_ChIP-ChIP_HESCs_Human2.03465123
37MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.02305529
38E2F7_22180533_ChIP-Seq_HELA_Human11.5484954
39HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.99265691
40VDR_23849224_ChIP-Seq_CD4+_Human1.94267991
41JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.94215477
42MYCN_18555785_ChIP-Seq_MESCs_Mouse1.82036582
43FOXP3_21729870_ChIP-Seq_TREG_Human1.80269714
44POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.78963567
45DCP1A_22483619_ChIP-Seq_HELA_Human1.78585784
46NANOG_18555785_ChIP-Seq_MESCs_Mouse1.74375030
47MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.73652207
48HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.73524969
49SOX2_16153702_ChIP-ChIP_HESCs_Human1.67393545
50PCGF2_27294783_Chip-Seq_ESCs_Mouse1.67209976
51E2F1_18555785_ChIP-Seq_MESCs_Mouse1.66789593
52FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.62037775
53PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.60493618
54AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.59002526
55YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.58278078
56CIITA_25753668_ChIP-Seq_RAJI_Human1.57156168
57ELK1_19687146_ChIP-ChIP_HELA_Human1.56306677
58GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.54652022
59TP63_19390658_ChIP-ChIP_HaCaT_Human1.54466919
60SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.53726661
61TTF2_22483619_ChIP-Seq_HELA_Human1.53494900
62CTBP1_25329375_ChIP-Seq_LNCAP_Human1.53489689
63SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.52510347
64OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.52350914
65CTBP2_25329375_ChIP-Seq_LNCAP_Human1.50330463
66KDM5A_27292631_Chip-Seq_BREAST_Human1.49760080
67HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.49597844
68MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.47889190
69GABP_19822575_ChIP-Seq_HepG2_Human1.46822434
70SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.46707158
71HOXB4_20404135_ChIP-ChIP_EML_Mouse1.46597698
72THAP11_20581084_ChIP-Seq_MESCs_Mouse1.46515606
73FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.43636774
74PIAS1_25552417_ChIP-Seq_VCAP_Human1.40906026
75NANOG_16153702_ChIP-ChIP_HESCs_Human1.37359174
76SMAD4_21799915_ChIP-Seq_A2780_Human1.36657310
77ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.36414427
78ELF1_17652178_ChIP-ChIP_JURKAT_Human1.32503899
79EZH2_27294783_Chip-Seq_NPCs_Mouse1.31666218
80RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.29624224
81ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.26763293
82SOX2_18555785_ChIP-Seq_MESCs_Mouse1.25563517
83SMAD3_21741376_ChIP-Seq_EPCs_Human1.25253335
84PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.24216234
85ZFX_18555785_ChIP-Seq_MESCs_Mouse1.24042505
86SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.23454282
87SUZ12_27294783_Chip-Seq_NPCs_Mouse1.22476589
88PADI4_21655091_ChIP-ChIP_MCF-7_Human1.21061568
89UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.20608629
90E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.20186751
91MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.18879285
92SOX9_26525672_Chip-Seq_HEART_Mouse1.18621690
93MYC_22102868_ChIP-Seq_BL_Human1.17783234
94POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.16368192
95YY1_21170310_ChIP-Seq_MESCs_Mouse1.15336346
96SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.14851651
97POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.14522795
98SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.13224238
99TOP2B_26459242_ChIP-Seq_MCF-7_Human1.12847550
100IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.12845197
101CBP_20019798_ChIP-Seq_JUKART_Human1.12845197
102CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.12696329
103SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.12451389
104STAT3_23295773_ChIP-Seq_U87_Human1.12371012
105NANOG_18555785_Chip-Seq_ESCs_Mouse1.10993140
106SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.10817769
107HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.10376512
108PCGF2_27294783_Chip-Seq_NPCs_Mouse1.10287599
109KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.10069196
110TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.10037922
111BCAT_22108803_ChIP-Seq_LS180_Human1.10018826
112ER_23166858_ChIP-Seq_MCF-7_Human1.09893413
113TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.09017067
114SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.08402352
115NFE2_27457419_Chip-Seq_LIVER_Mouse1.07452735
116ERG_20887958_ChIP-Seq_HPC-7_Mouse1.07403460
117TCF4_22108803_ChIP-Seq_LS180_Human1.04494143
118AR_25329375_ChIP-Seq_VCAP_Human1.03805481
119EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.02424588
120RNF2_27304074_Chip-Seq_NSC_Mouse1.00678780
121FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.00630963
122KLF4_18555785_ChIP-Seq_MESCs_Mouse0.99262846
123KLF5_20875108_ChIP-Seq_MESCs_Mouse0.98467403
124TCF4_23295773_ChIP-Seq_U87_Human0.98380408
125SRF_21415370_ChIP-Seq_HL-1_Mouse0.98110343
126TBX3_20139965_ChIP-Seq_ESCs_Mouse0.97252678
127NANOG_21062744_ChIP-ChIP_HESCs_Human0.97167067
128RBPJ_22232070_ChIP-Seq_NCS_Mouse0.96831255
129IRF8_21731497_ChIP-ChIP_J774_Mouse0.96815844
130MYC_18940864_ChIP-ChIP_HL60_Human0.96661179
131TBX3_20139965_ChIP-Seq_MESCs_Mouse0.96319750
132TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.95980215
133SPI1_23547873_ChIP-Seq_NB4_Human0.94817872
134CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.94742481
135TFEB_21752829_ChIP-Seq_HELA_Human0.94410946
136NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.94290579
137ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.92900843
138TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92802618
139POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.92802618
140NOTCH1_21737748_ChIP-Seq_TLL_Human0.88286568
141DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.88024193
142GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.87982944
143FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.86473011
144ESR1_15608294_ChIP-ChIP_MCF-7_Human0.84703827
145CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.83238631
146TCF3_18692474_ChIP-Seq_MEFs_Mouse0.81395464
147DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.80917080
148IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.80338897
149NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.79055014
150VDR_21846776_ChIP-Seq_THP-1_Human0.78317066
151IRF1_19129219_ChIP-ChIP_H3396_Human0.77021978
152CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.76234560
153KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.76205533
154CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.76202236
155PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.75488506
156RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.75208168
157CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.74568913
158POU5F1_16153702_ChIP-ChIP_HESCs_Human0.69329707
159NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.67899744
160STAT3_1855785_ChIP-Seq_MESCs_Mouse0.66993790

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.51207527
2MP0008057_abnormal_DNA_replication5.17536710
3MP0010094_abnormal_chromosome_stability5.07821206
4MP0003111_abnormal_nucleus_morphology4.80797336
5MP0003077_abnormal_cell_cycle4.17311167
6MP0004957_abnormal_blastocyst_morpholog4.03616834
7MP0008058_abnormal_DNA_repair3.45278768
8MP0003136_yellow_coat_color2.86215382
9MP0008007_abnormal_cellular_replicative2.76572374
10MP0008932_abnormal_embryonic_tissue2.60718884
11MP0010307_abnormal_tumor_latency2.53835246
12MP0003941_abnormal_skin_development2.53728861
13MP0003890_abnormal_embryonic-extraembry2.43451201
14MP0000350_abnormal_cell_proliferation2.13346448
15MP0001730_embryonic_growth_arrest2.12312591
16MP0001984_abnormal_olfaction2.10394247
17MP0002396_abnormal_hematopoietic_system2.04397073
18MP0001529_abnormal_vocalization2.03971960
19MP0005380_embryogenesis_phenotype1.82974630
20MP0001672_abnormal_embryogenesis/_devel1.82974630
21MP0003880_abnormal_central_pattern1.78526899
22MP0003718_maternal_effect1.76615224
23MP0006292_abnormal_olfactory_placode1.73588750
24MP0003786_premature_aging1.68076722
25MP0002233_abnormal_nose_morphology1.67277455
26MP0008877_abnormal_DNA_methylation1.63950028
27MP0004133_heterotaxia1.63120882
28MP0002751_abnormal_autonomic_nervous1.62472014
29MP0001697_abnormal_embryo_size1.62299129
30MP0000490_abnormal_crypts_of1.61729300
31MP0003567_abnormal_fetal_cardiomyocyte1.60970389
32MP0002736_abnormal_nociception_after1.57380031
33MP0003984_embryonic_growth_retardation1.57182343
34MP0003122_maternal_imprinting1.56734346
35MP0002088_abnormal_embryonic_growth/wei1.55675750
36MP0009697_abnormal_copulation1.55578207
37MP0010352_gastrointestinal_tract_polyps1.54399842
38MP0005645_abnormal_hypothalamus_physiol1.52723082
39MP0006054_spinal_hemorrhage1.49261451
40MP0002638_abnormal_pupillary_reflex1.47992091
41MP0003119_abnormal_digestive_system1.46332215
42MP0003123_paternal_imprinting1.46019499
43MP0010030_abnormal_orbit_morphology1.41820185
44MP0004808_abnormal_hematopoietic_stem1.40046343
45MP0003195_calcinosis1.39144830
46MP0002080_prenatal_lethality1.38122459
47MP0002085_abnormal_embryonic_tissue1.37571689
48MP0000631_abnormal_neuroendocrine_gland1.36998506
49MP0002086_abnormal_extraembryonic_tissu1.36518279
50MP0003011_delayed_dark_adaptation1.34705714
51MP0001299_abnormal_eye_distance/1.32902027
52MP0003121_genomic_imprinting1.31301367
53MP0004197_abnormal_fetal_growth/weight/1.30495801
54MP0001293_anophthalmia1.28496382
55MP0000313_abnormal_cell_death1.27979881
56MP0006072_abnormal_retinal_apoptosis1.27320013
57MP0005076_abnormal_cell_differentiation1.24223586
58MP0005075_abnormal_melanosome_morpholog1.23193654
59MP0003283_abnormal_digestive_organ1.22975498
60MP0002084_abnormal_developmental_patter1.22676685
61MP0001177_atelectasis1.22632230
62MP0002019_abnormal_tumor_incidence1.19318980
63MP0004145_abnormal_muscle_electrophysio1.18987826
64MP0006035_abnormal_mitochondrial_morpho1.16412257
65MP0001346_abnormal_lacrimal_gland1.15492576
66MP0002938_white_spotting1.15074710
67MP0005253_abnormal_eye_physiology1.14601654
68MP0000566_synostosis1.13090723
69MP0003937_abnormal_limbs/digits/tail_de1.10158085
70MP0006276_abnormal_autonomic_nervous1.09276610
71MP0002210_abnormal_sex_determination1.09193857
72MP0000462_abnormal_digestive_system1.09167469
73MP0002254_reproductive_system_inflammat1.09030489
74MP0005391_vision/eye_phenotype1.06154408
75MP0005551_abnormal_eye_electrophysiolog1.06000431
76MP0000049_abnormal_middle_ear1.04571276
77MP0000537_abnormal_urethra_morphology1.01184876
78MP0009672_abnormal_birth_weight0.98878202
79MP0000703_abnormal_thymus_morphology0.98488638
80MP0005248_abnormal_Harderian_gland0.98097479
81MP0001486_abnormal_startle_reflex0.97159353
82MP0009333_abnormal_splenocyte_physiolog0.95567183
83MP0002398_abnormal_bone_marrow0.94383365
84MP0001119_abnormal_female_reproductive0.94175610
85MP0004215_abnormal_myocardial_fiber0.94015520
86MP0002090_abnormal_vision0.93916101
87MP0004142_abnormal_muscle_tone0.93188182
88MP0002722_abnormal_immune_system0.92661816
89MP0009703_decreased_birth_body0.91969355
90MP0001145_abnormal_male_reproductive0.91384300
91MP0002163_abnormal_gland_morphology0.90217206
92MP0008789_abnormal_olfactory_epithelium0.89705506
93MP0002184_abnormal_innervation0.89552279
94MP0000778_abnormal_nervous_system0.89279999
95MP0004272_abnormal_basement_membrane0.89027559
96MP0000647_abnormal_sebaceous_gland0.87938484
97MP0009046_muscle_twitch0.85835435
98MP0001286_abnormal_eye_development0.84275567
99MP0003315_abnormal_perineum_morphology0.84122422
100MP0010678_abnormal_skin_adnexa0.82718882
101MP0001727_abnormal_embryo_implantation0.81633902
102MP0002092_abnormal_eye_morphology0.80923787
103MP0003755_abnormal_palate_morphology0.80803967
104MP0003861_abnormal_nervous_system0.80469524
105MP0005423_abnormal_somatic_nervous0.79547239
106MP0002752_abnormal_somatic_nervous0.79343286
107MP0002272_abnormal_nervous_system0.79019085
108MP0009250_abnormal_appendicular_skeleto0.78562282
109MP0001485_abnormal_pinna_reflex0.76792128
110MP0001919_abnormal_reproductive_system0.76461290
111MP0000689_abnormal_spleen_morphology0.76023850
112MP0003938_abnormal_ear_development0.75484993
113MP0000653_abnormal_sex_gland0.75270119
114MP0002111_abnormal_tail_morphology0.74505188
115MP0001968_abnormal_touch/_nociception0.74453572
116MP0003221_abnormal_cardiomyocyte_apopto0.74150733
117MP0001835_abnormal_antigen_presentation0.73940036
118MP0002095_abnormal_skin_pigmentation0.73536600
119MP0002277_abnormal_respiratory_mucosa0.73216187
120MP0005389_reproductive_system_phenotype0.71778528
121MP0001324_abnormal_eye_pigmentation0.71441915
122MP0001929_abnormal_gametogenesis0.70620095
123MP0002429_abnormal_blood_cell0.69364006
124MP0000428_abnormal_craniofacial_morphol0.69345313
125MP0005621_abnormal_cell_physiology0.68472042
126MP0003436_decreased_susceptibility_to0.67038334
127MP0008260_abnormal_autophagy0.65622160
128MP0001800_abnormal_humoral_immune0.64176273
129MP0001188_hyperpigmentation0.63673593
130MP0003950_abnormal_plasma_membrane0.63048061
131MP0002697_abnormal_eye_size0.62943403
132MP0005384_cellular_phenotype0.62155867
133MP0005195_abnormal_posterior_eye0.61831195
134MP0000716_abnormal_immune_system0.61637625
135MP0003787_abnormal_imprinting0.61282276
136MP0002006_tumorigenesis0.61218883
137MP0000432_abnormal_head_morphology0.60258587
138MP0003935_abnormal_craniofacial_develop0.60225137
139MP0002009_preneoplasia0.59987968
140MP0002075_abnormal_coat/hair_pigmentati0.59672161
141MP0002452_abnormal_antigen_presenting0.59551538
142MP0003705_abnormal_hypodermis_morpholog0.57532603
143MP0002102_abnormal_ear_morphology0.56909358
144MP0002282_abnormal_trachea_morphology0.56419261
145MP0000383_abnormal_hair_follicle0.56075780
146MP0005499_abnormal_olfactory_system0.56052781
147MP0005394_taste/olfaction_phenotype0.56052781

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)5.44965933
2Chromsome breakage (HP:0040012)5.31740341
3Birth length less than 3rd percentile (HP:0003561)4.87297889
4Agnosia (HP:0010524)4.74776768
5Abnormality of chromosome stability (HP:0003220)4.21821474
6Reticulocytopenia (HP:0001896)4.15247694
7Meckel diverticulum (HP:0002245)3.88197429
8Aplasia/Hypoplasia of the uvula (HP:0010293)3.82613215
9Abnormality of the preputium (HP:0100587)3.75430551
10Abnormality of the ileum (HP:0001549)3.74755687
11Colon cancer (HP:0003003)3.68967822
12Impulsivity (HP:0100710)3.68108483
13Ependymoma (HP:0002888)3.56986171
14Medulloblastoma (HP:0002885)3.56457002
15Breast hypoplasia (HP:0003187)3.24752780
16Rhabdomyosarcoma (HP:0002859)3.21316211
17Duodenal stenosis (HP:0100867)3.18277619
18Small intestinal stenosis (HP:0012848)3.18277619
19Myelodysplasia (HP:0002863)3.13061921
20Pancreatic fibrosis (HP:0100732)3.11976722
21Ectopic kidney (HP:0000086)3.10580546
22Patellar aplasia (HP:0006443)3.05592289
23Intestinal atresia (HP:0011100)3.05445814
24Congenital stationary night blindness (HP:0007642)3.02062989
25Abnormality of the carotid arteries (HP:0005344)3.01037336
26True hermaphroditism (HP:0010459)2.99305888
27Stenosis of the external auditory canal (HP:0000402)2.91105073
28Duplicated collecting system (HP:0000081)2.88588856
29Genital tract atresia (HP:0001827)2.87487378
30Aplasia/Hypoplasia of the patella (HP:0006498)2.87221719
31Hyperinsulinemic hypoglycemia (HP:0000825)2.84645699
32Absent radius (HP:0003974)2.75502715
33Abnormality of the duodenum (HP:0002246)2.72106375
34Astrocytoma (HP:0009592)2.70253639
35Abnormality of the astrocytes (HP:0100707)2.70253639
36Vaginal atresia (HP:0000148)2.69020956
37Degeneration of anterior horn cells (HP:0002398)2.65098054
38Abnormality of the anterior horn cell (HP:0006802)2.65098054
39Gastrointestinal atresia (HP:0002589)2.63266355
40Glioma (HP:0009733)2.62163253
41Clubbing of toes (HP:0100760)2.62102912
42Bone marrow hypocellularity (HP:0005528)2.60956008
43Hypoglycemic seizures (HP:0002173)2.60172736
44Pancreatic cysts (HP:0001737)2.57338061
45Medial flaring of the eyebrow (HP:0010747)2.55138812
46Abnormal lung lobation (HP:0002101)2.54625146
47Absent forearm bone (HP:0003953)2.52815450
48Aplasia involving forearm bones (HP:0009822)2.52815450
49Cafe-au-lait spot (HP:0000957)2.52780161
50Sloping forehead (HP:0000340)2.49601426
51Pendular nystagmus (HP:0012043)2.49599102
52Abnormal number of incisors (HP:0011064)2.49399862
53Hyperglycinemia (HP:0002154)2.47693141
54Abnormality of the renal collecting system (HP:0004742)2.44018178
55Nephroblastoma (Wilms tumor) (HP:0002667)2.43218002
56Septo-optic dysplasia (HP:0100842)2.41475608
57Triphalangeal thumb (HP:0001199)2.40468306
58Abnormality of methionine metabolism (HP:0010901)2.39993151
59Absent thumb (HP:0009777)2.34725859
60Gonadotropin excess (HP:0000837)2.34362503
61Chronic hepatic failure (HP:0100626)2.34268589
62Increased nuchal translucency (HP:0010880)2.33790415
63Methylmalonic acidemia (HP:0002912)2.31796697
64Increased hepatocellular lipid droplets (HP:0006565)2.31574398
65Congenital primary aphakia (HP:0007707)2.31564306
66Pallor (HP:0000980)2.28079678
67Nephrogenic diabetes insipidus (HP:0009806)2.27858115
68Abdominal situs inversus (HP:0003363)2.27254686
69Abnormality of abdominal situs (HP:0011620)2.27254686
70Decreased lacrimation (HP:0000633)2.26960885
71Aplasia/Hypoplasia of the tongue (HP:0010295)2.26341637
72Tracheoesophageal fistula (HP:0002575)2.26129351
73Embryonal renal neoplasm (HP:0011794)2.23853939
74Hypoglycemic coma (HP:0001325)2.23660640
75Cortical dysplasia (HP:0002539)2.23594349
76Gait imbalance (HP:0002141)2.22117432
77Abnormality of homocysteine metabolism (HP:0010919)2.20571862
78Homocystinuria (HP:0002156)2.20571862
79Cupped ear (HP:0000378)2.20132456
80Short tibia (HP:0005736)2.19849597
81Ureteral duplication (HP:0000073)2.18995766
82Neoplasm of striated muscle (HP:0009728)2.18820346
83Spinal muscular atrophy (HP:0007269)2.18611595
84Abnormality of DNA repair (HP:0003254)2.18166494
85Aplasia/Hypoplasia of the tibia (HP:0005772)2.17984164
86Prostate neoplasm (HP:0100787)2.17658377
87Lipid accumulation in hepatocytes (HP:0006561)2.16660144
88Spastic diplegia (HP:0001264)2.15519144
89Volvulus (HP:0002580)2.15028949
90Oral leukoplakia (HP:0002745)2.14917433
91Postaxial foot polydactyly (HP:0001830)2.14625663
92Nephronophthisis (HP:0000090)2.14305071
93Chorioretinal atrophy (HP:0000533)2.13487347
94Optic nerve coloboma (HP:0000588)2.11489188
95Bony spicule pigmentary retinopathy (HP:0007737)2.10307084
96Abnormality of aspartate family amino acid metabolism (HP:0010899)2.09764525
97Leukopenia (HP:0001882)2.09075169
98Carpal bone hypoplasia (HP:0001498)2.06226881
99Horseshoe kidney (HP:0000085)2.06139265
100Bifid tongue (HP:0010297)2.05350036
101Short thumb (HP:0009778)2.03732789
102Renal hypoplasia (HP:0000089)2.03674442
103Alacrima (HP:0000522)2.02973885
104Abnormality of pyrimidine metabolism (HP:0004353)2.02479101
105High anterior hairline (HP:0009890)2.01299402
106Anophthalmia (HP:0000528)2.00164514
107Neoplasm of the oral cavity (HP:0100649)1.99996083
108Acute lymphatic leukemia (HP:0006721)1.99543966
109Hyperglycinuria (HP:0003108)1.98972578
110Abnormality of the labia minora (HP:0012880)1.98391470
111Abnormal biliary tract physiology (HP:0012439)1.98261923
112Bile duct proliferation (HP:0001408)1.98261923
113Preaxial hand polydactyly (HP:0001177)1.97173836
114Cutaneous finger syndactyly (HP:0010554)1.94600469
115Abnormality of the metopic suture (HP:0005556)1.93496928
116Supernumerary spleens (HP:0009799)1.93128930
117Lymphoma (HP:0002665)1.92597336
118Atresia of the external auditory canal (HP:0000413)1.92347564
119Hypoplasia of the capital femoral epiphysis (HP:0003090)1.91949952
120Macrocytic anemia (HP:0001972)1.91502558
121Postaxial hand polydactyly (HP:0001162)1.91376801
122Abolished electroretinogram (ERG) (HP:0000550)1.90516540
123Neoplasm of the adrenal cortex (HP:0100641)1.90168176
124Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.89964936
125Pancreatic islet-cell hyperplasia (HP:0004510)1.89118938
126Abnormality of cells of the erythroid lineage (HP:0012130)1.89079189
127Malignant gastrointestinal tract tumors (HP:0006749)1.88568797
128Gastrointestinal carcinoma (HP:0002672)1.88568797
129Progressive inability to walk (HP:0002505)1.88138329
130Esophageal atresia (HP:0002032)1.87627977
131Abnormality of the fingertips (HP:0001211)1.85797396
132Optic nerve hypoplasia (HP:0000609)1.85203843
133Poor coordination (HP:0002370)1.84395337
134Amaurosis fugax (HP:0100576)1.84352244
135Arteriovenous malformation (HP:0100026)1.83795143
136Acute necrotizing encephalopathy (HP:0006965)1.83541378
137Renal cortical cysts (HP:0000803)1.83327473
13811 pairs of ribs (HP:0000878)1.83247418
139Preaxial foot polydactyly (HP:0001841)1.82556811
140Neoplasm of the pancreas (HP:0002894)1.82517863
141Prominent metopic ridge (HP:0005487)1.82197856
142Abnormality of the phalanges of the 2nd finger (HP:0009541)1.81841479
143Abnormal number of erythroid precursors (HP:0012131)1.80999326
144Prominent nose (HP:0000448)1.80470493
145Bilateral microphthalmos (HP:0007633)1.80304545
146Abnormality of serine family amino acid metabolism (HP:0010894)1.80156557
147Abnormality of glycine metabolism (HP:0010895)1.80156557
148Abnormality of the pancreatic islet cells (HP:0006476)1.80125877
149Abnormality of endocrine pancreas physiology (HP:0012093)1.80125877
150Proximal placement of thumb (HP:0009623)1.79682625
151Aplastic anemia (HP:0001915)1.78245178
152Acute encephalopathy (HP:0006846)1.78202182
153Neoplasm of the colon (HP:0100273)1.78108654
154Abnormality of the renal medulla (HP:0100957)1.77939433
155Abnormality of the septum pellucidum (HP:0007375)1.77624148
156Progressive macrocephaly (HP:0004481)1.76495784
157Deviation of the thumb (HP:0009603)1.75911696
158Hepatoblastoma (HP:0002884)1.74458785
159Abnormality of midbrain morphology (HP:0002418)1.73909054
160Molar tooth sign on MRI (HP:0002419)1.73909054
161Facial hemangioma (HP:0000329)1.72921689
162Anencephaly (HP:0002323)1.72880858
163Abnormality of incisor morphology (HP:0011063)1.72624080
164Abnormality of serum amino acid levels (HP:0003112)1.72519157
165Glossoptosis (HP:0000162)1.71636994
166Premature graying of hair (HP:0002216)1.71262749
167Choanal atresia (HP:0000453)1.70769729
168Freckling (HP:0001480)1.70712710
169Transitional cell carcinoma of the bladder (HP:0006740)1.70598605
170Aqueductal stenosis (HP:0002410)1.70558586
171Dandy-Walker malformation (HP:0001305)1.68835689
172Aplasia/Hypoplasia of the earlobes (HP:0009906)1.68725497
173Selective tooth agenesis (HP:0001592)1.68018548
174Deep philtrum (HP:0002002)1.67730669
175Capillary hemangiomas (HP:0005306)1.67148193
176Biliary tract neoplasm (HP:0100574)1.66998076
177Basal cell carcinoma (HP:0002671)1.66761580
178Absent eyebrow (HP:0002223)1.66622313
179Increased CSF lactate (HP:0002490)1.66222812
180Aplasia/Hypoplasia of the sternum (HP:0006714)1.65714057
181Rough bone trabeculation (HP:0100670)1.65524885

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.74770755
2CDC74.69196308
3WEE14.53773784
4CCNB12.78772466
5NEK22.76858882
6SRPK12.74615657
7EIF2AK12.60166530
8BRSK22.59089991
9NUAK12.56764471
10FGFR22.44683924
11NEK12.42909659
12TTK2.25719302
13TRIM282.24955523
14TLK12.22619962
15FRK2.20737479
16MAP3K42.15555227
17PLK12.12843072
18MKNK12.07515615
19BMPR1B2.04000910
20WNK32.03570591
21MST42.00851105
22ACVR1B1.98498625
23CASK1.97827748
24PLK41.85896399
25AURKB1.85092403
26TNIK1.80834305
27PLK31.75286323
28BRSK11.75033500
29MAP4K21.72745155
30VRK11.66649373
31CDK71.64310109
32ATR1.63079237
33AKT31.59307762
34CDK41.58853859
35MAP2K71.56033425
36CHEK21.55208182
37STK161.53757037
38CDK121.49032303
39ZAK1.45841336
40BCR1.45075801
41MKNK21.42363474
42DYRK31.40395890
43MELK1.39091258
44PLK21.37473137
45EPHA31.35440446
46OBSCN1.34593403
47BRD41.34469655
48CSNK1G11.32083072
49YES11.31285993
50CDK81.26077593
51CLK11.25699469
52RPS6KB21.25411180
53AURKA1.24899044
54SCYL21.24036944
55PINK11.23177966
56PASK1.21570827
57BCKDK1.20569406
58TAF11.15543304
59CHEK11.12444153
60CDK61.12441817
61STK391.11867696
62VRK21.10162846
63CSNK1G31.08543946
64RPS6KA41.08138302
65FGFR11.07689201
66EIF2AK21.05822572
67LATS11.04414285
68STK41.03151355
69TIE11.01013265
70CSNK1G21.00545763
71EPHA21.00190454
72BRAF0.97591254
73EIF2AK30.97489229
74MAP3K80.97160209
75ERBB40.96551071
76TSSK60.96074192
77TGFBR10.95952679
78ATM0.86812484
79PBK0.86279802
80KIT0.83651050
81MAP3K100.81730282
82CDK20.80584961
83GRK10.80246817
84ERBB30.79607815
85EPHA40.77040099
86MAPK130.76385518
87FLT30.76339955
88RAF10.75620177
89CSNK1A1L0.75340446
90PNCK0.70569211
91STK30.68260936
92CDK10.65594777
93NME20.64665034
94TGFBR20.64528285
95PIM10.64291795
96INSRR0.64232574
97OXSR10.63940095
98CSF1R0.61261331
99TAOK20.60865568
100ADRBK20.58032156
101STK240.57064885
102PRKCE0.55923982
103NME10.55265306
104NLK0.53428282
105NEK60.52229579
106BTK0.52062693
107ITK0.51398886
108IRAK40.48954364
109TAOK30.48517864
110RPS6KA50.48145660
111TEC0.46495275
112CDK30.46417294
113KSR10.45428726
114CSNK2A10.45327658
115PIK3CA0.43207220
116PKN10.42352634
117CSNK2A20.42314422
118IRAK20.41994230
119STK100.40989922
120MARK30.39864366
121MAP2K40.38089284
122MARK10.37047614
123PRKCG0.37044383
124MAP4K10.36508341
125MAP3K60.35269247
126FGFR30.34738483
127SGK20.33660704
128LRRK20.33530356
129PRKDC0.32389448
130CAMK1D0.31907990
131PAK30.31720920
132MAPK140.31401745
133FER0.29830815
134CSNK1A10.29502542
135PAK10.29077518
136DYRK20.27717897
137STK38L0.27282137
138TRPM70.26835227
139LYN0.25882905
140AKT10.24938355
141RPS6KC10.24632736
142RPS6KL10.24632736
143PIK3CG0.24045717
144ALK0.24028976
145NEK90.21355949
146MATK0.20526548
147RPS6KA60.19148061
148CDK90.18567546
149ARAF0.18245729
150PIM20.18192175
151PAK40.17884063
152MAPKAPK20.17699991

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.50970531
2Mismatch repair_Homo sapiens_hsa034305.02645888
3Homologous recombination_Homo sapiens_hsa034403.61704904
4Base excision repair_Homo sapiens_hsa034103.43180020
5Cell cycle_Homo sapiens_hsa041103.30917498
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.26037672
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.25038604
8Fanconi anemia pathway_Homo sapiens_hsa034603.22409080
9Spliceosome_Homo sapiens_hsa030403.07464728
10Nucleotide excision repair_Homo sapiens_hsa034203.05166445
11Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.97286883
12RNA polymerase_Homo sapiens_hsa030202.87731419
13RNA transport_Homo sapiens_hsa030132.83751946
14Propanoate metabolism_Homo sapiens_hsa006402.69393316
15One carbon pool by folate_Homo sapiens_hsa006702.47350040
16Ribosome_Homo sapiens_hsa030102.46351888
17Steroid biosynthesis_Homo sapiens_hsa001002.38296530
18Pyrimidine metabolism_Homo sapiens_hsa002402.25307836
19Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.01957410
20Non-homologous end-joining_Homo sapiens_hsa034501.97699654
21Phototransduction_Homo sapiens_hsa047441.92508666
22Basal transcription factors_Homo sapiens_hsa030221.84892561
23Butanoate metabolism_Homo sapiens_hsa006501.81162358
24p53 signaling pathway_Homo sapiens_hsa041151.77982873
25Proteasome_Homo sapiens_hsa030501.76566531
26Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.75280704
27Oxidative phosphorylation_Homo sapiens_hsa001901.74508443
28Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.71415800
29mRNA surveillance pathway_Homo sapiens_hsa030151.69399245
30Parkinsons disease_Homo sapiens_hsa050121.65303539
31RNA degradation_Homo sapiens_hsa030181.64409960
32Nitrogen metabolism_Homo sapiens_hsa009101.56896206
33Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.33008479
34Systemic lupus erythematosus_Homo sapiens_hsa053221.31035931
35Pyruvate metabolism_Homo sapiens_hsa006201.29630397
36Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.27359165
37Huntingtons disease_Homo sapiens_hsa050161.27235650
38Vitamin B6 metabolism_Homo sapiens_hsa007501.25950578
39Epstein-Barr virus infection_Homo sapiens_hsa051691.23680865
40Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.22242629
41Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.22076330
42Fatty acid elongation_Homo sapiens_hsa000621.21076048
43Purine metabolism_Homo sapiens_hsa002301.19853622
44Peroxisome_Homo sapiens_hsa041461.19077410
45Folate biosynthesis_Homo sapiens_hsa007901.18252981
46Herpes simplex infection_Homo sapiens_hsa051681.14120827
47Primary bile acid biosynthesis_Homo sapiens_hsa001201.12303300
48Maturity onset diabetes of the young_Homo sapiens_hsa049501.09928321
49Oocyte meiosis_Homo sapiens_hsa041141.03893829
50Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.00548738
51Fatty acid metabolism_Homo sapiens_hsa012120.96956951
52Viral carcinogenesis_Homo sapiens_hsa052030.93912487
53Alzheimers disease_Homo sapiens_hsa050100.91208169
54MicroRNAs in cancer_Homo sapiens_hsa052060.89304827
55HTLV-I infection_Homo sapiens_hsa051660.87875182
56Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.85423594
57Colorectal cancer_Homo sapiens_hsa052100.83870382
58Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.80806317
59Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.80439143
60Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.79959888
61Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.69969069
62Nicotine addiction_Homo sapiens_hsa050330.68354800
63Antigen processing and presentation_Homo sapiens_hsa046120.67287977
64Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.66880204
65Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.66578386
66Selenocompound metabolism_Homo sapiens_hsa004500.66258093
67Small cell lung cancer_Homo sapiens_hsa052220.65795877
68Carbon metabolism_Homo sapiens_hsa012000.65461367
69Transcriptional misregulation in cancer_Homo sapiens_hsa052020.63011988
70NF-kappa B signaling pathway_Homo sapiens_hsa040640.62791176
71Metabolic pathways_Homo sapiens_hsa011000.62152574
72Taste transduction_Homo sapiens_hsa047420.60765219
73Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.58269700
74Hepatitis B_Homo sapiens_hsa051610.57760137
75Fatty acid degradation_Homo sapiens_hsa000710.55021830
76Fatty acid biosynthesis_Homo sapiens_hsa000610.54822385
77Drug metabolism - other enzymes_Homo sapiens_hsa009830.52070567
78Chronic myeloid leukemia_Homo sapiens_hsa052200.51922950
79Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.49679662
80Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.49540582
81Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.49516727
82Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.48932005
83Legionellosis_Homo sapiens_hsa051340.48055857
84Retinol metabolism_Homo sapiens_hsa008300.47443939
85Vitamin digestion and absorption_Homo sapiens_hsa049770.46931794
86Pentose phosphate pathway_Homo sapiens_hsa000300.46912903
87mTOR signaling pathway_Homo sapiens_hsa041500.46419026
88Primary immunodeficiency_Homo sapiens_hsa053400.46323871
89Apoptosis_Homo sapiens_hsa042100.46148848
90Thyroid cancer_Homo sapiens_hsa052160.45913097
91Cysteine and methionine metabolism_Homo sapiens_hsa002700.44785761
92Prostate cancer_Homo sapiens_hsa052150.43260063
93Cardiac muscle contraction_Homo sapiens_hsa042600.42908433
94Alcoholism_Homo sapiens_hsa050340.42277204
95Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.41678230
96Pancreatic cancer_Homo sapiens_hsa052120.41158809
97TGF-beta signaling pathway_Homo sapiens_hsa043500.40796327
98B cell receptor signaling pathway_Homo sapiens_hsa046620.40202394
99Notch signaling pathway_Homo sapiens_hsa043300.40113963
100Sulfur metabolism_Homo sapiens_hsa009200.39903706
101Measles_Homo sapiens_hsa051620.38650470
102Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.37698724
103Pentose and glucuronate interconversions_Homo sapiens_hsa000400.36868859
104Hippo signaling pathway_Homo sapiens_hsa043900.36347951
105FoxO signaling pathway_Homo sapiens_hsa040680.35599501
106Lysine degradation_Homo sapiens_hsa003100.35435864
107N-Glycan biosynthesis_Homo sapiens_hsa005100.35270187
108Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.34364031
109NOD-like receptor signaling pathway_Homo sapiens_hsa046210.34238006
110Tryptophan metabolism_Homo sapiens_hsa003800.34115530
111Biosynthesis of amino acids_Homo sapiens_hsa012300.33169650
112Basal cell carcinoma_Homo sapiens_hsa052170.33130561
113Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.32536734
114Glutamatergic synapse_Homo sapiens_hsa047240.31063516
115GABAergic synapse_Homo sapiens_hsa047270.30987947
116Long-term depression_Homo sapiens_hsa047300.29449573
117Influenza A_Homo sapiens_hsa051640.28836373
118Pathways in cancer_Homo sapiens_hsa052000.28200867
119Circadian rhythm_Homo sapiens_hsa047100.28047434
120Olfactory transduction_Homo sapiens_hsa047400.27992701
121Caffeine metabolism_Homo sapiens_hsa002320.26895210
122HIF-1 signaling pathway_Homo sapiens_hsa040660.26886386
123Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.26833823
124Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.26501031
125Intestinal immune network for IgA production_Homo sapiens_hsa046720.26027432
126Non-small cell lung cancer_Homo sapiens_hsa052230.25946418
127Tight junction_Homo sapiens_hsa045300.25642360
128Galactose metabolism_Homo sapiens_hsa000520.25374946
129Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.25035502
130Renin-angiotensin system_Homo sapiens_hsa046140.24980139
131Melanoma_Homo sapiens_hsa052180.22267189
132Glycerolipid metabolism_Homo sapiens_hsa005610.22106791
133Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.21383236
134Glutathione metabolism_Homo sapiens_hsa004800.21368804
135Hedgehog signaling pathway_Homo sapiens_hsa043400.20198208
136Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.19836382
137Thyroid hormone signaling pathway_Homo sapiens_hsa049190.18683673
138Acute myeloid leukemia_Homo sapiens_hsa052210.16443193
139Central carbon metabolism in cancer_Homo sapiens_hsa052300.15769031
140Protein export_Homo sapiens_hsa030600.15084000
141Type I diabetes mellitus_Homo sapiens_hsa049400.14138349
142Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.13757629
143Endometrial cancer_Homo sapiens_hsa052130.12528926
144Leishmaniasis_Homo sapiens_hsa051400.11804721
145Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.11385446
146Fructose and mannose metabolism_Homo sapiens_hsa000510.10499262
147Adherens junction_Homo sapiens_hsa045200.09880093
148Viral myocarditis_Homo sapiens_hsa054160.09169976
149Bladder cancer_Homo sapiens_hsa052190.08345050
150Shigellosis_Homo sapiens_hsa051310.07603762
151Graft-versus-host disease_Homo sapiens_hsa053320.07093545
152Wnt signaling pathway_Homo sapiens_hsa043100.06887594
153Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.06542910

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