FOXM1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein localization to kinetochore (GO:0034501)5.80612289
2protein localization to chromosome, centromeric region (GO:0071459)5.37544826
3mitotic sister chromatid segregation (GO:0000070)5.26401009
4sister chromatid segregation (GO:0000819)5.13530000
5DNA unwinding involved in DNA replication (GO:0006268)4.99353566
6mitotic chromosome condensation (GO:0007076)4.95104115
7regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.80363724
8nuclear pore complex assembly (GO:0051292)4.54734687
9nuclear pore organization (GO:0006999)4.49741251
10mitotic sister chromatid cohesion (GO:0007064)4.45273760
11mitotic metaphase plate congression (GO:0007080)4.44515659
12kinetochore organization (GO:0051383)4.43941199
13regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.28130267
14mitotic nuclear envelope disassembly (GO:0007077)4.25890544
15attachment of spindle microtubules to kinetochore (GO:0008608)4.20535360
16regulation of spindle organization (GO:0090224)4.10720829
17establishment of integrated proviral latency (GO:0075713)4.04312921
18metaphase plate congression (GO:0051310)3.99460716
19nuclear envelope disassembly (GO:0051081)3.96440192
20membrane disassembly (GO:0030397)3.96440192
21protein localization to chromosome (GO:0034502)3.93457145
22positive regulation of chromosome segregation (GO:0051984)3.92314205
23DNA replication-dependent nucleosome organization (GO:0034723)3.91729937
24DNA replication-dependent nucleosome assembly (GO:0006335)3.91729937
25chromosome condensation (GO:0030261)3.91307194
26regulation of sister chromatid cohesion (GO:0007063)3.89927385
27DNA strand elongation involved in DNA replication (GO:0006271)3.88693902
28heterochromatin organization (GO:0070828)3.88186474
29meiotic chromosome segregation (GO:0045132)3.87610529
30establishment of chromosome localization (GO:0051303)3.79401037
31DNA replication initiation (GO:0006270)3.75947968
32positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.75920634
33positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.75920634
34positive regulation of mitotic sister chromatid separation (GO:1901970)3.75920634
35kinetochore assembly (GO:0051382)3.74312211
36regulation of chromosome segregation (GO:0051983)3.70613717
37DNA strand elongation (GO:0022616)3.68717766
38regulation of mitotic spindle organization (GO:0060236)3.64791503
39microtubule depolymerization (GO:0007019)3.64662761
40chromosome segregation (GO:0007059)3.54134242
41protein complex localization (GO:0031503)3.53799640
42chromatin remodeling at centromere (GO:0031055)3.52584916
43regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.52405666
44DNA replication checkpoint (GO:0000076)3.51167978
45DNA packaging (GO:0006323)3.48082131
46DNA replication-independent nucleosome organization (GO:0034724)3.47933376
47DNA replication-independent nucleosome assembly (GO:0006336)3.47933376
48telomere maintenance via semi-conservative replication (GO:0032201)3.47411288
49CENP-A containing nucleosome assembly (GO:0034080)3.46443623
50pore complex assembly (GO:0046931)3.44524055
51regulation of mammary gland epithelial cell proliferation (GO:0033599)3.43553200
52chromatin assembly or disassembly (GO:0006333)3.42749468
53mitotic recombination (GO:0006312)3.42074744
54DNA duplex unwinding (GO:0032508)3.41232751
55DNA geometric change (GO:0032392)3.40343640
56spindle checkpoint (GO:0031577)3.40275251
57positive regulation of DNA-dependent DNA replication (GO:2000105)3.36353647
58pre-miRNA processing (GO:0031054)3.34192521
59regulation of histone H3-K9 methylation (GO:0051570)3.30955162
60negative regulation of chromosome segregation (GO:0051985)3.30575897
61regulation of mitotic metaphase/anaphase transition (GO:0030071)3.29088804
62negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.28973641
63telomere maintenance via recombination (GO:0000722)3.27954214
64histone exchange (GO:0043486)3.26659462
65DNA conformation change (GO:0071103)3.26394048
66DNA strand renaturation (GO:0000733)3.22900730
67spindle assembly checkpoint (GO:0071173)3.22856480
68regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.22076480
69chromatin assembly (GO:0031497)3.21768258
70DNA topological change (GO:0006265)3.20466567
71negative regulation of mitotic sister chromatid separation (GO:2000816)3.19681185
72negative regulation of mitotic sister chromatid segregation (GO:0033048)3.19681185
73negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.19681185
74negative regulation of sister chromatid segregation (GO:0033046)3.19681185
75nuclear envelope organization (GO:0006998)3.17382756
76ATP-dependent chromatin remodeling (GO:0043044)3.15049558
77regulation of mitotic sister chromatid separation (GO:0010965)3.13782347
78regulation of mitotic sister chromatid segregation (GO:0033047)3.13782347
79regulation of sister chromatid segregation (GO:0033045)3.13782347
80regulation of centrosome cycle (GO:0046605)3.13274961
81mitotic spindle assembly checkpoint (GO:0007094)3.11143723
82negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.10883108
83mitotic spindle checkpoint (GO:0071174)3.08802067
84spliceosomal tri-snRNP complex assembly (GO:0000244)3.08158300
85mRNA stabilization (GO:0048255)3.08104850
86RNA stabilization (GO:0043489)3.08104850
87formation of translation preinitiation complex (GO:0001731)3.06734615
88negative regulation of RNA splicing (GO:0033119)3.05140408
89translesion synthesis (GO:0019985)3.03226082
90regulation of RNA export from nucleus (GO:0046831)3.02271420
91dosage compensation (GO:0007549)3.00536327
92L-serine metabolic process (GO:0006563)2.99592222
93negative regulation of histone methylation (GO:0031061)2.98451501
94proline biosynthetic process (GO:0006561)2.98093584
95establishment of viral latency (GO:0019043)2.97469451
96nucleosome disassembly (GO:0006337)2.95433695
97protein-DNA complex disassembly (GO:0032986)2.95433695
98spindle assembly involved in mitosis (GO:0090307)2.95344606
99folic acid-containing compound biosynthetic process (GO:0009396)2.94954809
100histone-serine phosphorylation (GO:0035404)2.94025686
101negative regulation of mRNA processing (GO:0050686)2.93076208
102cellular protein complex localization (GO:0034629)2.92839332
103telomere maintenance via telomere lengthening (GO:0010833)2.92794368
104regulation of DNA endoreduplication (GO:0032875)2.92137855
105regulation of centriole replication (GO:0046599)2.91504127
106nucleotide-excision repair, DNA gap filling (GO:0006297)2.91473020
107DNA ligation (GO:0006266)2.90977363
108DNA synthesis involved in DNA repair (GO:0000731)2.88670649
109protein K6-linked ubiquitination (GO:0085020)2.87095152
110spindle organization (GO:0007051)2.87047080
111peptidyl-arginine omega-N-methylation (GO:0035247)2.85312468
112mitotic cytokinesis (GO:0000281)2.85168530
113histone phosphorylation (GO:0016572)2.83617372
114folic acid metabolic process (GO:0046655)2.82032509
115nucleobase-containing small molecule interconversion (GO:0015949)2.79452398
116regulation of translational termination (GO:0006449)2.79086671
1173-UTR-mediated mRNA stabilization (GO:0070935)2.79003287
118regulation of telomere maintenance via telomerase (GO:0032210)2.78454396
119double-strand break repair via nonhomologous end joining (GO:0006303)2.78114925
120non-recombinational repair (GO:0000726)2.78114925
121Golgi transport vesicle coating (GO:0048200)2.78083346
122COPI coating of Golgi vesicle (GO:0048205)2.78083346
123chromosome organization (GO:0051276)2.77606735
124negative regulation of mRNA metabolic process (GO:1903312)2.75228156
125spindle assembly (GO:0051225)2.74644118
126paraxial mesoderm development (GO:0048339)2.74155023
127mitotic G1 DNA damage checkpoint (GO:0031571)2.73676176
128regulation of translational fidelity (GO:0006450)2.70131338
129* mitotic cell cycle (GO:0000278)2.68901108
130microtubule cytoskeleton organization involved in mitosis (GO:1902850)2.65592176

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human7.59357236
2* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.49291953
3* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human4.27418471
4MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.36512976
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.25573528
6EGR1_19374776_ChIP-ChIP_THP-1_Human2.99143346
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.88980087
8AR_21909140_ChIP-Seq_LNCAP_Human2.75787165
9MYC_22102868_ChIP-Seq_BL_Human2.49721673
10MYC_19079543_ChIP-ChIP_MESCs_Mouse2.49678612
11E2F1_21310950_ChIP-Seq_MCF-7_Human2.39302979
12MYC_19030024_ChIP-ChIP_MESCs_Mouse2.17940971
13KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.12895785
14XRN2_22483619_ChIP-Seq_HELA_Human2.00327903
15E2F7_22180533_ChIP-Seq_HELA_Human10.4214806
16NELFA_20434984_ChIP-Seq_ESCs_Mouse1.92204475
17MYC_18358816_ChIP-ChIP_MESCs_Mouse1.91615969
18* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.88767970
19VDR_21846776_ChIP-Seq_THP-1_Human1.70180712
20* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.69734363
21* TP63_19390658_ChIP-ChIP_HaCaT_Human1.67845677
22CIITA_25753668_ChIP-Seq_RAJI_Human1.67247782
23NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.64967043
24EST1_17652178_ChIP-ChIP_JURKAT_Human1.62368881
25ZNF263_19887448_ChIP-Seq_K562_Human1.62343453
26CREB1_15753290_ChIP-ChIP_HEK293T_Human1.60577603
27ESR1_15608294_ChIP-ChIP_MCF-7_Human1.55390393
28KDM5A_27292631_Chip-Seq_BREAST_Human1.47566522
29ETS1_20019798_ChIP-Seq_JURKAT_Human1.46848590
30CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.45529515
31TTF2_22483619_ChIP-Seq_HELA_Human1.44381507
32NANOG_18555785_ChIP-Seq_MESCs_Mouse1.42017199
33ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.41513673
34KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.39753346
35CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.38026166
36POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.37998592
37HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.37713950
38FOXP3_21729870_ChIP-Seq_TREG_Human1.35656585
39DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.30239864
40VDR_23849224_ChIP-Seq_CD4+_Human1.30213106
41DCP1A_22483619_ChIP-Seq_HELA_Human1.30162864
42* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.27911661
43* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.25997648
44TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.25277703
45* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.25180275
46SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.25045289
47RACK7_27058665_Chip-Seq_MCF-7_Human1.24665816
48STAT6_21828071_ChIP-Seq_BEAS2B_Human1.24013797
49CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.23355128
50TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.23043519
51GABP_19822575_ChIP-Seq_HepG2_Human1.22579614
52* MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.22414536
53YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.21700759
54PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.21155986
55CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.18383893
56SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.18343780
57PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.18102909
58E2F1_18555785_ChIP-Seq_MESCs_Mouse1.17801317
59SALL1_21062744_ChIP-ChIP_HESCs_Human1.15331216
60DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.14922362
61TCF7_22412390_ChIP-Seq_EML_Mouse1.13979220
62SOX2_18555785_ChIP-Seq_MESCs_Mouse1.11624687
63HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.11154107
64NANOG_21062744_ChIP-ChIP_HESCs_Human1.10930951
65NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.06946032
66UTX_26944678_Chip-Seq_JUKART_Human1.06780288
67TP63_17297297_ChIP-ChIP_HaCaT_Human1.06597148
68ELK1_19687146_ChIP-ChIP_HELA_Human1.05621476
69THAP11_20581084_ChIP-Seq_MESCs_Mouse1.04091114
70KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.03743335
71GABP_17652178_ChIP-ChIP_JURKAT_Human1.02746570
72STAT3_1855785_ChIP-Seq_MESCs_Mouse1.02287322
73ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.01825597
74TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.00885121
75RBPJ_22232070_ChIP-Seq_NCS_Mouse1.00774679
76LXR_22292898_ChIP-Seq_THP-1_Human1.00617313
77YY1_21170310_ChIP-Seq_MESCs_Mouse1.00528343
78POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.97638819
79KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.96628051
80* TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.96434778
81HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.95731136
82JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.95183204
83KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.94981509
84TET1_21451524_ChIP-Seq_MESCs_Mouse0.94599154
85RARG_19884340_ChIP-ChIP_MEFs_Mouse0.94409206
86SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.94352519
87HOXB4_20404135_ChIP-ChIP_EML_Mouse0.93759208
88P300_27058665_Chip-Seq_ZR-75-30cells_Human0.93323643
89SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.93310176
90CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.93034656
91* TFEB_21752829_ChIP-Seq_HELA_Human0.92686562
92KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.92336069
93ELK3_25401928_ChIP-Seq_HUVEC_Human0.92168251
94ELF1_17652178_ChIP-ChIP_JURKAT_Human0.91130943
95ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.91035627
96MAF_26560356_Chip-Seq_TH1_Human0.90545524
97PADI4_21655091_ChIP-ChIP_MCF-7_Human0.89868950
98CHD1_26751641_Chip-Seq_LNCaP_Human0.88533679
99EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.87978084
100SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.87068722
101RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.85822834
102PKCTHETA_26484144_Chip-Seq_BREAST_Human0.85796843
103SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.85615247
104HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.85346200
105ZFP281_18757296_ChIP-ChIP_E14_Mouse0.85274599
106SOX17_20123909_ChIP-Seq_XEN_Mouse0.85050046
107KDM2B_26808549_Chip-Seq_DND41_Human0.84781628
108ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.84698028
109HIF1A_21447827_ChIP-Seq_MCF-7_Human0.84349106
110SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.83619280
111P68_20966046_ChIP-Seq_HELA_Human0.83171359
112* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.83136247
113POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.83095078
114KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.82298539
115CLOCK_20551151_ChIP-Seq_293T_Human0.81804178
116MYB_26560356_Chip-Seq_TH1_Human0.81215951
117FOXP1_21924763_ChIP-Seq_HESCs_Human0.81106853
118KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.81050745
119ATF3_27146783_Chip-Seq_COLON_Human0.80895204
120NCOR1_26117541_ChIP-Seq_K562_Human0.80527687
121* TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.80297092
122FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.79976371
123TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.77743900
124* BRD4_27068464_Chip-Seq_AML-cells_Mouse0.76989373
125MYB_26560356_Chip-Seq_TH2_Human0.75774474
126VDR_24763502_ChIP-Seq_THP-1_Human0.75389650
127CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.74783931
128ERG_20887958_ChIP-Seq_HPC-7_Mouse0.74304011
129TCF3_18692474_ChIP-Seq_MEFs_Mouse0.74259004

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003111_abnormal_nucleus_morphology4.09480761
2MP0003693_abnormal_embryo_hatching4.00593363
3MP0010094_abnormal_chromosome_stability4.00233048
4* MP0003077_abnormal_cell_cycle3.41100991
5MP0004957_abnormal_blastocyst_morpholog3.39164197
6MP0008057_abnormal_DNA_replication3.06698004
7MP0010352_gastrointestinal_tract_polyps2.39174978
8MP0008007_abnormal_cellular_replicative2.37148770
9MP0003705_abnormal_hypodermis_morpholog2.30490046
10MP0005076_abnormal_cell_differentiation2.25833198
11MP0001730_embryonic_growth_arrest2.25566332
12MP0003123_paternal_imprinting2.23309522
13MP0010307_abnormal_tumor_latency2.18102607
14MP0000350_abnormal_cell_proliferation2.17628801
15MP0008932_abnormal_embryonic_tissue2.15795904
16MP0008877_abnormal_DNA_methylation2.07058032
17MP0010030_abnormal_orbit_morphology2.01176060
18MP0008058_abnormal_DNA_repair1.99160611
19MP0002396_abnormal_hematopoietic_system1.96863480
20MP0005380_embryogenesis_phenotype1.84887261
21MP0001672_abnormal_embryogenesis/_devel1.84887261
22MP0004808_abnormal_hematopoietic_stem1.79718476
23MP0001697_abnormal_embryo_size1.78532496
24MP0004197_abnormal_fetal_growth/weight/1.76963881
25MP0002085_abnormal_embryonic_tissue1.75740359
26MP0005171_absent_coat_pigmentation1.70366354
27MP0009278_abnormal_bone_marrow1.70024276
28MP0003984_embryonic_growth_retardation1.69487766
29MP0002084_abnormal_developmental_patter1.69346340
30MP0004185_abnormal_adipocyte_glucose1.68058357
31MP0003121_genomic_imprinting1.66939796
32MP0002088_abnormal_embryonic_growth/wei1.66011893
33MP0002086_abnormal_extraembryonic_tissu1.54979091
34MP0009053_abnormal_anal_canal1.54136048
35* MP0002080_prenatal_lethality1.51789548
36MP0010234_abnormal_vibrissa_follicle1.47219923
37MP0001346_abnormal_lacrimal_gland1.46508083
38MP0000537_abnormal_urethra_morphology1.45159341
39MP0000490_abnormal_crypts_of1.41445204
40MP0005501_abnormal_skin_physiology1.34086267
41MP0003567_abnormal_fetal_cardiomyocyte1.30281538
42MP0000733_abnormal_muscle_development1.28082874
43MP0002210_abnormal_sex_determination1.25128174
44MP0000313_abnormal_cell_death1.23350545
45* MP0002019_abnormal_tumor_incidence1.22938198
46MP0003937_abnormal_limbs/digits/tail_de1.22667424
47MP0001849_ear_inflammation1.18995672
48MP0001661_extended_life_span1.18411460
49MP0003786_premature_aging1.17603561
50MP0000003_abnormal_adipose_tissue1.17037219
51MP0001293_anophthalmia1.16386243
52MP0001545_abnormal_hematopoietic_system1.16294242
53MP0005397_hematopoietic_system_phenotyp1.16294242
54MP0005409_darkened_coat_color1.15397811
55MP0003566_abnormal_cell_adhesion1.15379466
56MP0000428_abnormal_craniofacial_morphol1.14964716
57MP0003890_abnormal_embryonic-extraembry1.14874280
58MP0006054_spinal_hemorrhage1.14462551
59MP0001929_abnormal_gametogenesis1.14366075
60MP0000703_abnormal_thymus_morphology1.12005905
61MP0009672_abnormal_birth_weight1.09895910
62MP0003718_maternal_effect1.08733401
63MP0000569_abnormal_digit_pigmentation1.08655112
64MP0000566_synostosis1.08480614
65MP0002653_abnormal_ependyma_morphology1.08294030
66MP0003136_yellow_coat_color1.08192376
67MP0009697_abnormal_copulation1.08056254
68MP0001145_abnormal_male_reproductive1.07955258
69MP0001915_intracranial_hemorrhage1.05429884
70MP0008438_abnormal_cutaneous_collagen1.05166923
71MP0001348_abnormal_lacrimal_gland1.03919765
72MP0005023_abnormal_wound_healing1.02783575
73MP0002060_abnormal_skin_morphology1.02413051
74MP0003935_abnormal_craniofacial_develop0.99664379
75MP0009703_decreased_birth_body0.99451350
76MP0000432_abnormal_head_morphology0.99385915
77MP0002796_impaired_skin_barrier0.99307411
78MP0005623_abnormal_meninges_morphology0.97504475
79MP0004272_abnormal_basement_membrane0.95648804
80MP0003119_abnormal_digestive_system0.95578705
81MP0002111_abnormal_tail_morphology0.95423222
82* MP0003115_abnormal_respiratory_system0.94342902
83MP0000534_abnormal_ureter_morphology0.94076022
84MP0002092_abnormal_eye_morphology0.94013633
85MP0004858_abnormal_nervous_system0.92879024
86MP0003941_abnormal_skin_development0.92297883
87MP0003950_abnormal_plasma_membrane0.91552791
88MP0002697_abnormal_eye_size0.91171430
89MP0002932_abnormal_joint_morphology0.90653121
90MP0000653_abnormal_sex_gland0.90624492
91MP0000762_abnormal_tongue_morphology0.88678603
92* MP0002925_abnormal_cardiovascular_devel0.88612617
93MP0000358_abnormal_cell_content/0.88568100
94MP0003385_abnormal_body_wall0.87875505
95MP0003453_abnormal_keratinocyte_physiol0.86916290
96MP0003755_abnormal_palate_morphology0.86815900
97MP0002009_preneoplasia0.84394595
98MP0002398_abnormal_bone_marrow0.83994205
99MP0002877_abnormal_melanocyte_morpholog0.83939027
100MP0009333_abnormal_splenocyte_physiolog0.83443122
101MP0002089_abnormal_postnatal_growth/wei0.83427400
102MP0000858_altered_metastatic_potential0.83359402
103MP0003315_abnormal_perineum_morphology0.82733060
104MP0005451_abnormal_body_composition0.81044803
105MP0000678_abnormal_parathyroid_gland0.80098463
106MP0002282_abnormal_trachea_morphology0.79956378
107MP0003300_gastrointestinal_ulcer0.79774413
108MP0005621_abnormal_cell_physiology0.78336894
109MP0002722_abnormal_immune_system0.77977823
110MP0000579_abnormal_nail_morphology0.77789470
111MP0003942_abnormal_urinary_system0.77615135
112MP0001286_abnormal_eye_development0.76246290
113MP0000049_abnormal_middle_ear0.75850517
114MP0003861_abnormal_nervous_system0.73388218
115MP0009250_abnormal_appendicular_skeleto0.73109564
116MP0005257_abnormal_intraocular_pressure0.72472951
117MP0004233_abnormal_muscle_weight0.71415732
118MP0002116_abnormal_craniofacial_bone0.70954664
119MP0005410_abnormal_fertilization0.70869359
120MP0003698_abnormal_male_reproductive0.70447346
121MP0005384_cellular_phenotype0.70186517
122MP0002098_abnormal_vibrissa_morphology0.69735074
123MP0005197_abnormal_uvea_morphology0.69149973
124MP0002114_abnormal_axial_skeleton0.67962735
125MP0008770_decreased_survivor_rate0.66703698
126MP0001216_abnormal_epidermal_layer0.66284573
127MP0002249_abnormal_larynx_morphology0.66284549
128MP0000689_abnormal_spleen_morphology0.65646961
129MP0000467_abnormal_esophagus_morphology0.65611309
130MP0003763_abnormal_thymus_physiology0.65396463
131MP0001119_abnormal_female_reproductive0.64317784
132MP0000383_abnormal_hair_follicle0.63605501
133MP0003091_abnormal_cell_migration0.63556755
134MP0000477_abnormal_intestine_morphology0.63429718

Predicted human phenotypes

RankGene SetZ-score
1Short 4th metacarpal (HP:0010044)3.73114507
2Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.73114507
3Chromsome breakage (HP:0040012)3.63136373
4Chromosomal breakage induced by crosslinking agents (HP:0003221)3.37903756
5Increased nuchal translucency (HP:0010880)3.32286867
6Selective tooth agenesis (HP:0001592)3.16834256
7Ectopic kidney (HP:0000086)2.87613189
8Volvulus (HP:0002580)2.86547797
9Reticulocytopenia (HP:0001896)2.83140234
10Deviation of the thumb (HP:0009603)2.72907313
11Abnormality of the 4th metacarpal (HP:0010012)2.68646352
12Proximal placement of thumb (HP:0009623)2.68165875
13Impulsivity (HP:0100710)2.66492029
14Abnormality of chromosome stability (HP:0003220)2.65025419
15Medulloblastoma (HP:0002885)2.63152268
16Meckel diverticulum (HP:0002245)2.60383872
17Patellar aplasia (HP:0006443)2.52738295
18Ependymoma (HP:0002888)2.52159058
19Renal duplication (HP:0000075)2.50371862
20Colon cancer (HP:0003003)2.46040833
21Abnormality of the ileum (HP:0001549)2.45717197
22Poikiloderma (HP:0001029)2.42492423
23Insomnia (HP:0100785)2.39829797
24Aplasia/Hypoplasia of the uvula (HP:0010293)2.38637298
25Small intestinal stenosis (HP:0012848)2.36374608
26Duodenal stenosis (HP:0100867)2.36374608
27Aplasia/Hypoplasia of the patella (HP:0006498)2.36203519
28High pitched voice (HP:0001620)2.35520656
29Asymmetry of the thorax (HP:0001555)2.34757923
30Premature rupture of membranes (HP:0001788)2.33301259
31Hyperacusis (HP:0010780)2.33203067
32Abnormal number of incisors (HP:0011064)2.32374203
33High anterior hairline (HP:0009890)2.32038174
34Broad distal phalanx of finger (HP:0009836)2.29035464
35Atresia of the external auditory canal (HP:0000413)2.25319376
36Abnormality of the preputium (HP:0100587)2.23826193
37Abnormality of the fingertips (HP:0001211)2.22650523
38Facial hemangioma (HP:0000329)2.19929933
39Trismus (HP:0000211)2.17193045
40Long eyelashes (HP:0000527)2.15140512
41Abnormality of the carotid arteries (HP:0005344)2.14987991
42Myelodysplasia (HP:0002863)2.13426281
43Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.12558082
44Absent epiphyses (HP:0010577)2.12558082
45Shallow orbits (HP:0000586)2.11671934
46Trigonocephaly (HP:0000243)2.11412233
47Basal cell carcinoma (HP:0002671)2.09488560
48Abnormality of the umbilical cord (HP:0010881)2.07153827
49Overlapping toe (HP:0001845)2.06775638
50Abnormal lung lobation (HP:0002101)2.06235614
51Rhabdomyosarcoma (HP:0002859)2.04875270
52Birth length less than 3rd percentile (HP:0003561)2.03319314
53Ankle contracture (HP:0006466)2.02240495
54Cafe-au-lait spot (HP:0000957)2.01948282
55Protrusio acetabuli (HP:0003179)2.01679757
56Absent radius (HP:0003974)2.01509846
57Progressive muscle weakness (HP:0003323)2.01020672
58Duplication of thumb phalanx (HP:0009942)2.00730107
59Sloping forehead (HP:0000340)1.99505326
60Abnormality of the astrocytes (HP:0100707)1.97439963
61Astrocytoma (HP:0009592)1.97439963
62Neoplasm of striated muscle (HP:0009728)1.95846707
63Breast hypoplasia (HP:0003187)1.95482230
64Increased density of long bones (HP:0006392)1.93977697
65Prominent nose (HP:0000448)1.91171767
66Nephroblastoma (Wilms tumor) (HP:0002667)1.91031094
67Heterotopia (HP:0002282)1.90606736
68Abnormality of the duodenum (HP:0002246)1.90009516
69Absent thumb (HP:0009777)1.89302064
70Broad thumb (HP:0011304)1.88764933
71Testicular atrophy (HP:0000029)1.88520261
72Abnormality of the calcaneus (HP:0008364)1.88248047
73Absent forearm bone (HP:0003953)1.88067915
74Aplasia involving forearm bones (HP:0009822)1.88067915
75Tracheoesophageal fistula (HP:0002575)1.87813910
76Short thumb (HP:0009778)1.87475552
77Cortical dysplasia (HP:0002539)1.87228947
78Aplasia/Hypoplasia of the sacrum (HP:0008517)1.86652945
79Elfin facies (HP:0004428)1.85643265
80Abnormality of the phalanges of the hallux (HP:0010057)1.84898656
81Urethral obstruction (HP:0000796)1.84848700
82Renovascular hypertension (HP:0100817)1.84678980
83Squamous cell carcinoma (HP:0002860)1.84660981
84Coronal craniosynostosis (HP:0004440)1.83415681
85Duplicated collecting system (HP:0000081)1.82961050
86Capillary hemangiomas (HP:0005306)1.81368724
87Missing ribs (HP:0000921)1.81134149
88Skin tags (HP:0010609)1.80964495
89Intestinal fistula (HP:0100819)1.80717668
90Abnormality of the distal phalanx of the thumb (HP:0009617)1.79884671
91Neoplasm of the oral cavity (HP:0100649)1.79675805
92Disproportionate tall stature (HP:0001519)1.79519833
93Abnormality of the labia minora (HP:0012880)1.78763665
94Deep philtrum (HP:0002002)1.78532818
95Embryonal renal neoplasm (HP:0011794)1.78436339
96Broad palm (HP:0001169)1.78352972
97Choanal atresia (HP:0000453)1.78328012
98Turricephaly (HP:0000262)1.77752085
99Supernumerary ribs (HP:0005815)1.77603938
100Long palpebral fissure (HP:0000637)1.77042726
101Broad phalanges of the hand (HP:0009768)1.76132267
102Neoplasm of the pancreas (HP:0002894)1.75763152
103Aplasia/Hypoplasia of the sternum (HP:0006714)1.75710669
104Small epiphyses (HP:0010585)1.75652063
105Skull defect (HP:0001362)1.73612895
106Carpal bone hypoplasia (HP:0001498)1.73078253
107Malignant gastrointestinal tract tumors (HP:0006749)1.71482213
108Gastrointestinal carcinoma (HP:0002672)1.71482213
109Hypoplasia of the capital femoral epiphysis (HP:0003090)1.71129872
110Rectal prolapse (HP:0002035)1.70549027
111Microvesicular hepatic steatosis (HP:0001414)1.70291216
112Rib fusion (HP:0000902)1.70008580
113Ulnar bowing (HP:0003031)1.69965681
114Abnormality of the anterior horn cell (HP:0006802)1.69518851
115Degeneration of anterior horn cells (HP:0002398)1.69518851
116Abnormality of abdominal situs (HP:0011620)1.69349864
117Abdominal situs inversus (HP:0003363)1.69349864
118Bowel diverticulosis (HP:0005222)1.68912007
119Glossoptosis (HP:0000162)1.68390442
120Genu recurvatum (HP:0002816)1.68373679
121Vaginal fistula (HP:0004320)1.68026438
122Rectal fistula (HP:0100590)1.68010045
123Rectovaginal fistula (HP:0000143)1.68010045
124Multiple enchondromatosis (HP:0005701)1.67634534
125Abnormality of the fetal cardiovascular system (HP:0010948)1.67590517
126Abnormal umbilical cord blood vessels (HP:0011403)1.67590517
127Single umbilical artery (HP:0001195)1.67590517
128Pterygium (HP:0001059)1.67173144
129Abnormality of chromosome segregation (HP:0002916)1.66493192
130Broad face (HP:0000283)1.66402886
131Abnormality of cells of the erythroid lineage (HP:0012130)1.66049439
13211 pairs of ribs (HP:0000878)1.66012265
133Cutis marmorata (HP:0000965)1.65973202
134Septate vagina (HP:0001153)1.65792657
135Achilles tendon contracture (HP:0001771)1.65767891
136Glioma (HP:0009733)1.65717276
137Overriding aorta (HP:0002623)1.65587670
138Supernumerary bones of the axial skeleton (HP:0009144)1.64649643
139Preauricular skin tag (HP:0000384)1.63199204
140Horseshoe kidney (HP:0000085)1.62574145
141Unilateral renal agenesis (HP:0000122)1.62232623
142Back pain (HP:0003418)1.62048594
143Microglossia (HP:0000171)1.61487805
144Bowed forearm bones (HP:0003956)1.61198596
145Bowing of the arm (HP:0006488)1.61198596
146Hypopigmentation of the fundus (HP:0007894)1.60794382
147Patellar dislocation (HP:0002999)1.59487992
148Flared metaphyses (HP:0003015)1.59411848

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.58424044
2NEK23.92199732
3CDK123.74714298
4BUB13.37720571
5SMG13.29227069
6MAP3K103.17290131
7WEE13.10154360
8EEF2K3.01905588
9TTK2.57859656
10VRK22.42679569
11IRAK32.22723899
12PBK2.06384299
13PKN22.02979372
14MST1R1.94858220
15TRIB31.89095784
16PLK11.87503811
17STK101.83231189
18BRSK21.82617171
19AURKB1.74242237
20LATS11.71743114
21CDK71.70267090
22NEK11.63261591
23ATR1.59721011
24STK31.56798759
25MAP3K81.55276298
26RPS6KB21.54933990
27TESK21.51022368
28RPS6KA41.49127470
29STK41.45429399
30PASK1.42975357
31BRD41.42814622
32SRPK11.42334978
33* CDK41.41770090
34MET1.41544709
35TAF11.41335364
36CHEK11.40890976
37MKNK11.38294457
38BRSK11.33050444
39SIK11.32077537
40TESK11.28712321
41PLK41.28453679
42ICK1.25211411
43* CHEK21.23166858
44PAK41.21702949
45EIF2AK11.21405385
46TTN1.14286682
47PLK31.12835365
48LATS21.10397777
49MELK1.10060053
50PTK21.08667181
51MTOR1.06213341
52ATM1.04401037
53ACVR1B1.03104406
54DYRK31.02834093
55MKNK21.02198792
56AURKA0.96420841
57LRRK20.95789739
58* CDK20.93235307
59ERBB40.92674997
60BRAF0.90952443
61TLK10.86451897
62ALK0.81937165
63PTK60.76589773
64PAK20.76419255
65MAP4K10.76352435
66* CDK10.74825258
67TGFBR10.74714236
68EPHA20.71843935
69CLK10.71685707
70SCYL20.71057953
71BMX0.70429494
72TSSK60.69813421
73MAP3K90.68757436
74PIM10.68619252
75CCNB10.66976680
76PNCK0.66058294
77PRKD30.65925831
78PAK10.65359974
79CDK90.65047583
80PRPF4B0.65020072
81PDGFRA0.64461777
82CDK80.64059138
83CDK150.63764956
84CDK180.63108033
85IRAK20.57439333
86VRK10.56835904
87EIF2AK20.54724175
88TAOK10.54538801
89ZAK0.54194829
90FGFR40.51924097
91* CDK60.51866028
92GRK60.51843982
93PRKCI0.51159761
94ILK0.50642564
95CAMK1D0.50394010
96CDK140.50075571
97STK38L0.49893473
98NME20.49247603
99LIMK10.48517365
100SIK30.45763329
101MAP2K30.43756685
102PRKDC0.43567616
103LMTK20.43278065
104FGFR10.43186112
105AKT20.42805150
106DMPK0.40815186
107ARAF0.40271938
108DYRK1B0.40086002
109TAOK20.38699025
110FLT30.38279185
111KSR20.37883265
112NTRK10.36436170
113CSNK1D0.36389562
114* MAPK140.36360947
115CSNK2A20.34733815
116MAPK10.33019191
117AKT10.32861785
118CSNK2A10.32107258
119CAMK1G0.29849355
120DAPK10.29204423
121MARK30.28820642
122MAPK110.28803028
123MAPKAPK20.28784766
124BTK0.28696866
125CSNK1E0.28392337
126PDGFRB0.27628195
127CSF1R0.26653665
128CDK11A0.26538903
129TYRO30.26368883
130RPS6KA10.25499540

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.45190335
2Mismatch repair_Homo sapiens_hsa034303.67624137
3Cell cycle_Homo sapiens_hsa041103.46130942
4RNA transport_Homo sapiens_hsa030132.94039363
5Spliceosome_Homo sapiens_hsa030402.93744848
6Base excision repair_Homo sapiens_hsa034102.83376389
7Homologous recombination_Homo sapiens_hsa034402.80467333
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.45366977
9Fanconi anemia pathway_Homo sapiens_hsa034602.42116272
10Nucleotide excision repair_Homo sapiens_hsa034202.35174162
11One carbon pool by folate_Homo sapiens_hsa006702.26671900
12mRNA surveillance pathway_Homo sapiens_hsa030152.18941601
13Non-homologous end-joining_Homo sapiens_hsa034501.92186395
14p53 signaling pathway_Homo sapiens_hsa041151.90723924
15Ribosome_Homo sapiens_hsa030101.84766934
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.73245990
17RNA degradation_Homo sapiens_hsa030181.64561642
18MicroRNAs in cancer_Homo sapiens_hsa052061.56029595
19Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.53508965
20Sulfur relay system_Homo sapiens_hsa041221.49522507
21Basal transcription factors_Homo sapiens_hsa030221.45666131
22Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.42736389
23Oocyte meiosis_Homo sapiens_hsa041141.42376732
24RNA polymerase_Homo sapiens_hsa030201.41528833
25Small cell lung cancer_Homo sapiens_hsa052221.41441305
26Pyrimidine metabolism_Homo sapiens_hsa002401.39719192
27Viral carcinogenesis_Homo sapiens_hsa052031.37885559
28Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.35581580
29Chronic myeloid leukemia_Homo sapiens_hsa052201.32614530
302-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.31153895
31HTLV-I infection_Homo sapiens_hsa051661.30869449
32Basal cell carcinoma_Homo sapiens_hsa052171.25152803
33Systemic lupus erythematosus_Homo sapiens_hsa053221.24651418
34Vitamin B6 metabolism_Homo sapiens_hsa007501.15462757
35Epstein-Barr virus infection_Homo sapiens_hsa051691.12979442
36Herpes simplex infection_Homo sapiens_hsa051681.12362666
37Cysteine and methionine metabolism_Homo sapiens_hsa002701.10938425
38N-Glycan biosynthesis_Homo sapiens_hsa005101.10158171
39Carbon metabolism_Homo sapiens_hsa012001.08724377
40Fructose and mannose metabolism_Homo sapiens_hsa000511.08419649
41Hippo signaling pathway_Homo sapiens_hsa043901.07709428
42Adherens junction_Homo sapiens_hsa045201.07110679
43Colorectal cancer_Homo sapiens_hsa052101.05216910
44Notch signaling pathway_Homo sapiens_hsa043300.97748240
45Bladder cancer_Homo sapiens_hsa052190.97491322
46Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.94827002
47Hedgehog signaling pathway_Homo sapiens_hsa043400.92758849
48Transcriptional misregulation in cancer_Homo sapiens_hsa052020.92647193
49Lysine degradation_Homo sapiens_hsa003100.91948271
50Pancreatic cancer_Homo sapiens_hsa052120.91308579
51Antigen processing and presentation_Homo sapiens_hsa046120.90703068
52Non-small cell lung cancer_Homo sapiens_hsa052230.89819475
53Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.88495627
54TGF-beta signaling pathway_Homo sapiens_hsa043500.87562710
55Thyroid cancer_Homo sapiens_hsa052160.86836955
56Hepatitis B_Homo sapiens_hsa051610.85456781
57Viral myocarditis_Homo sapiens_hsa054160.83337249
58Proteoglycans in cancer_Homo sapiens_hsa052050.83073757
59Prostate cancer_Homo sapiens_hsa052150.82755183
60Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.81780707
61Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.81618106
62Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.81606562
63Folate biosynthesis_Homo sapiens_hsa007900.76361333
64Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.73940202
65Pyruvate metabolism_Homo sapiens_hsa006200.73585821
66mTOR signaling pathway_Homo sapiens_hsa041500.73079192
67Apoptosis_Homo sapiens_hsa042100.72980385
68Proteasome_Homo sapiens_hsa030500.71928142
69Pathways in cancer_Homo sapiens_hsa052000.70950233
70Endometrial cancer_Homo sapiens_hsa052130.70502717
71Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.69986375
72Shigellosis_Homo sapiens_hsa051310.69841219
73Primary immunodeficiency_Homo sapiens_hsa053400.67944515
74Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.67821314
75Central carbon metabolism in cancer_Homo sapiens_hsa052300.66032077
76Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.64048575
77Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.63801380
78Focal adhesion_Homo sapiens_hsa045100.62626346
79Galactose metabolism_Homo sapiens_hsa000520.62491146
80Acute myeloid leukemia_Homo sapiens_hsa052210.61143497
81Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.59887376
82Wnt signaling pathway_Homo sapiens_hsa043100.59873679
83Leukocyte transendothelial migration_Homo sapiens_hsa046700.59705946
84Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.59665800
85Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.59537459
86B cell receptor signaling pathway_Homo sapiens_hsa046620.58521719
87Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.57935678
88Thyroid hormone signaling pathway_Homo sapiens_hsa049190.57651294
89Purine metabolism_Homo sapiens_hsa002300.56179755
90Measles_Homo sapiens_hsa051620.55515764
91Glioma_Homo sapiens_hsa052140.54771146
92Melanoma_Homo sapiens_hsa052180.54373538
93Selenocompound metabolism_Homo sapiens_hsa004500.51436416
94Pentose phosphate pathway_Homo sapiens_hsa000300.51203072
95Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.50992319
96FoxO signaling pathway_Homo sapiens_hsa040680.50417328
97Alcoholism_Homo sapiens_hsa050340.50305460
98HIF-1 signaling pathway_Homo sapiens_hsa040660.49907767
99Longevity regulating pathway - mammal_Homo sapiens_hsa042110.49891819
100Regulation of actin cytoskeleton_Homo sapiens_hsa048100.49713731
101ECM-receptor interaction_Homo sapiens_hsa045120.49032547
102Steroid biosynthesis_Homo sapiens_hsa001000.48383836
103AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.47794824
104Neurotrophin signaling pathway_Homo sapiens_hsa047220.47695859
105NF-kappa B signaling pathway_Homo sapiens_hsa040640.47005544
106VEGF signaling pathway_Homo sapiens_hsa043700.44715243
107Influenza A_Homo sapiens_hsa051640.44015493
108Legionellosis_Homo sapiens_hsa051340.43449565
109Tight junction_Homo sapiens_hsa045300.43190014
110Renal cell carcinoma_Homo sapiens_hsa052110.42663587
111Toxoplasmosis_Homo sapiens_hsa051450.42194607
112ErbB signaling pathway_Homo sapiens_hsa040120.41272211
113Biosynthesis of amino acids_Homo sapiens_hsa012300.41155869
114Melanogenesis_Homo sapiens_hsa049160.39715172
115PI3K-Akt signaling pathway_Homo sapiens_hsa041510.38728041
116Insulin signaling pathway_Homo sapiens_hsa049100.38449316
117Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.38014111
118Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.37040082
119Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.34926875
120T cell receptor signaling pathway_Homo sapiens_hsa046600.34843653
121Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.34328769
122Prion diseases_Homo sapiens_hsa050200.33882452
123Platelet activation_Homo sapiens_hsa046110.33170962
124Dorso-ventral axis formation_Homo sapiens_hsa043200.30647222
125NOD-like receptor signaling pathway_Homo sapiens_hsa046210.30543192
126Cyanoamino acid metabolism_Homo sapiens_hsa004600.30116335
127AMPK signaling pathway_Homo sapiens_hsa041520.29835485
128Leishmaniasis_Homo sapiens_hsa051400.29644041
129Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.28724532
130Hematopoietic cell lineage_Homo sapiens_hsa046400.27617863

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