FOXK1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cytoplasmic mRNA processing body assembly (GO:0033962)4.06605767
2positive regulation of histone deacetylation (GO:0031065)3.91184096
3positive thymic T cell selection (GO:0045059)3.59380695
4negative regulation of cell killing (GO:0031342)3.55365825
5negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.55365825
6thymic T cell selection (GO:0045061)3.45656154
7positive regulation of gamma-delta T cell activation (GO:0046645)3.42321272
8antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.41203422
9antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.41203422
10regulation of hippo signaling (GO:0035330)3.30900265
11positive regulation of CREB transcription factor activity (GO:0032793)3.28351514
12regulation of gamma-delta T cell differentiation (GO:0045586)3.26334817
13antigen processing and presentation of endogenous antigen (GO:0019883)3.21535764
14negative thymic T cell selection (GO:0045060)3.20952742
15regulation of interleukin-12 biosynthetic process (GO:0045075)3.15896522
16negative T cell selection (GO:0043383)3.14700185
17insulin-like growth factor receptor signaling pathway (GO:0048009)3.14399795
18T cell selection (GO:0045058)3.07945997
19positive T cell selection (GO:0043368)3.07758250
20negative regulation of cell size (GO:0045792)3.00873647
21regulation of gamma-delta T cell activation (GO:0046643)2.95564790
22regulation of axon extension involved in axon guidance (GO:0048841)2.85404156
23plasma membrane repair (GO:0001778)2.82328816
24semaphorin-plexin signaling pathway (GO:0071526)2.79559559
25NLS-bearing protein import into nucleus (GO:0006607)2.76623322
26myoblast fusion (GO:0007520)2.73055983
27neural tube development (GO:0021915)2.72180192
28growth hormone receptor signaling pathway (GO:0060396)2.72032129
29endothelial cell chemotaxis (GO:0035767)2.70563620
30regulation of T cell tolerance induction (GO:0002664)2.68702206
31syncytium formation by plasma membrane fusion (GO:0000768)2.67258698
32positive regulation of tolerance induction (GO:0002645)2.66903345
33negative regulation of myotube differentiation (GO:0010832)2.64983598
34interkinetic nuclear migration (GO:0022027)2.62294386
35JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.60874427
36regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.59003082
37regulation of endothelial cell chemotaxis (GO:2001026)2.58843407
38histone H3-K36 demethylation (GO:0070544)2.58322218
39positive regulation of fatty acid oxidation (GO:0046321)2.57260589
40pre-miRNA processing (GO:0031054)2.55731175
41receptor catabolic process (GO:0032801)2.55034241
42striated muscle atrophy (GO:0014891)2.54661592
43nucleus localization (GO:0051647)2.54472568
44hemidesmosome assembly (GO:0031581)2.53679349
45cytoskeletal anchoring at plasma membrane (GO:0007016)2.53506681
46regulation of axon guidance (GO:1902667)2.51667676
47regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.51640579
48embryonic camera-type eye morphogenesis (GO:0048596)2.51334166
49histone H3-K4 trimethylation (GO:0080182)2.50902098
50regulation of ARF protein signal transduction (GO:0032012)2.50824615
51negative regulation of fatty acid transport (GO:2000192)2.49912132
52positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.48483860
53histone H3-K4 methylation (GO:0051568)2.47368623
54positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.46308272
55positive regulation of protein deacetylation (GO:0090312)2.46123997
56tolerance induction (GO:0002507)2.45967853
57pericardium development (GO:0060039)2.44940084
58synaptic vesicle docking involved in exocytosis (GO:0016081)2.43959670
59histone H3-K9 methylation (GO:0051567)2.41695089
60glucocorticoid receptor signaling pathway (GO:0042921)2.41646589
61response to interleukin-15 (GO:0070672)2.41463463
62regulation of histone deacetylation (GO:0031063)2.38396602
63camera-type eye morphogenesis (GO:0048593)2.37768519
64histone H3-K9 modification (GO:0061647)2.37688120
65regulation of somitogenesis (GO:0014807)2.34032500
66positive regulation of Rap GTPase activity (GO:0032854)2.32585511
67positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.31837277
68cell-substrate junction assembly (GO:0007044)2.31728343
69mannose metabolic process (GO:0006013)2.29905496
70peptidyl-lysine methylation (GO:0018022)2.29705020
71cellular response to growth hormone stimulus (GO:0071378)2.29453047
72regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.29227859
73regulation of tolerance induction (GO:0002643)2.29109370
74positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.28538853
75regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.28538853
76embryonic retina morphogenesis in camera-type eye (GO:0060059)2.27791716
77ear development (GO:0043583)2.27526428
78corticosteroid receptor signaling pathway (GO:0031958)2.27361870
79natural killer cell differentiation (GO:0001779)2.26213664
80morphogenesis of an epithelial sheet (GO:0002011)2.25129000
81positive regulation of glycogen metabolic process (GO:0070875)2.24453105
82embryonic eye morphogenesis (GO:0048048)2.23984952
83negative regulation of cytosolic calcium ion concentration (GO:0051481)2.23918188
84negative regulation of viral release from host cell (GO:1902187)2.23885248
85adherens junction assembly (GO:0034333)2.23302497
86positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.23300472
87stress fiber assembly (GO:0043149)2.22899904
88sodium ion export (GO:0071436)2.22729399
89histone H3-K9 demethylation (GO:0033169)2.22229801
90osteoblast development (GO:0002076)2.21930605
91regulation of ARF GTPase activity (GO:0032312)2.21848888
92protein localization to endosome (GO:0036010)2.21704904
93phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.21645255
94desmosome organization (GO:0002934)2.21382273
95peptidyl-lysine dimethylation (GO:0018027)2.21356543
96snRNA transcription (GO:0009301)2.20989265
97negative regulation of erythrocyte differentiation (GO:0045647)2.20275580
98syncytium formation (GO:0006949)2.20038565
99collecting duct development (GO:0072044)2.19996850
100regulation of p38MAPK cascade (GO:1900744)2.19804586
101cell-substrate adherens junction assembly (GO:0007045)2.19038903
102focal adhesion assembly (GO:0048041)2.19038903
103signal complex assembly (GO:0007172)2.18537740
104response to laminar fluid shear stress (GO:0034616)2.18213567
105regulation of fatty acid beta-oxidation (GO:0031998)2.18206910
106peptidyl-threonine phosphorylation (GO:0018107)2.17720643
107regulation of NFAT protein import into nucleus (GO:0051532)2.17523849
108leukocyte aggregation (GO:0070486)2.16696048
109activation of JUN kinase activity (GO:0007257)2.16241634
110response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.15853005
111peptidyl-threonine modification (GO:0018210)2.15730798
112cortical actin cytoskeleton organization (GO:0030866)2.15522910
113establishment of nucleus localization (GO:0040023)2.15162622
114atrioventricular valve morphogenesis (GO:0003181)2.13480681
115Notch signaling involved in heart development (GO:0061314)2.13078111
116heart valve formation (GO:0003188)2.13027015
117regulation of protein deacetylation (GO:0090311)2.12809511
118intracellular estrogen receptor signaling pathway (GO:0030520)2.12591164
119activation of Rac GTPase activity (GO:0032863)2.12430156
120fibroblast migration (GO:0010761)2.11607278
121negative regulation of cardiac muscle tissue growth (GO:0055022)2.11551858
122negative regulation of heart growth (GO:0061117)2.11551858
123positive regulation of fatty acid beta-oxidation (GO:0032000)2.10628543
124regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.10438897
125positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.10438897
126regulation of fatty acid oxidation (GO:0046320)2.09227994
127positive regulation of mRNA catabolic process (GO:0061014)2.08926843
128negative regulation of Ras protein signal transduction (GO:0046580)2.08395856
129venous blood vessel morphogenesis (GO:0048845)2.08383594
130positive regulation of glycogen biosynthetic process (GO:0045725)2.07803000
131cell migration in hindbrain (GO:0021535)2.07465477
132positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.07291495
133negative regulation of granulocyte differentiation (GO:0030853)2.07013717
134positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.06346202
135stress granule assembly (GO:0034063)2.06078003
136germ cell migration (GO:0008354)2.05837676
137negative regulation of catenin import into nucleus (GO:0035414)2.05740842
138regulation of clathrin-mediated endocytosis (GO:2000369)2.05372598
139regulation of mRNA catabolic process (GO:0061013)2.05156332
140central nervous system projection neuron axonogenesis (GO:0021952)2.04967480
141skin morphogenesis (GO:0043589)2.04967428
142regulation of B cell receptor signaling pathway (GO:0050855)2.04459312
143protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)2.04054301
144peptidyl-lysine trimethylation (GO:0018023)2.03847998
145eye morphogenesis (GO:0048592)2.02969884
146response to fluid shear stress (GO:0034405)2.02487641
147axonal fasciculation (GO:0007413)2.02240143
148response to inactivity (GO:0014854)2.01576577
149auditory receptor cell differentiation (GO:0042491)2.01413359
150negative regulation of TOR signaling (GO:0032007)2.01276978
151positive regulation of epithelial to mesenchymal transition (GO:0010718)2.00953773
152regulation of Rap GTPase activity (GO:0032317)1.99952150
153negative regulation of small GTPase mediated signal transduction (GO:0051058)1.99716936
154myotube differentiation (GO:0014902)1.99522181
155dichotomous subdivision of an epithelial terminal unit (GO:0060600)1.98650819
156coronary vasculature morphogenesis (GO:0060977)1.98643389
157locomotory exploration behavior (GO:0035641)1.98218600
158skeletal muscle adaptation (GO:0043501)1.98009192
159regulation of alkaline phosphatase activity (GO:0010692)1.97948735
160antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G1.97161618
161apoptotic cell clearance (GO:0043277)1.95348644
162T cell costimulation (GO:0031295)1.94813443
163heart morphogenesis (GO:0003007)1.94117229
164mRNA stabilization (GO:0048255)1.92580683
165RNA stabilization (GO:0043489)1.92580683
166histone lysine methylation (GO:0034968)1.91826216
167regulation of extracellular matrix disassembly (GO:0010715)1.89608270
168regulation of cholesterol homeostasis (GO:2000188)1.89327819
169positive regulation of blood vessel endothelial cell migration (GO:0043536)1.88865390
170hippo signaling (GO:0035329)1.88272463

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.72304134
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.68084780
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.34982094
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.09736766
5MYC_22102868_ChIP-Seq_BL_Human2.99285776
6EGR1_19374776_ChIP-ChIP_THP-1_Human2.90636044
7EZH2_22144423_ChIP-Seq_EOC_Human2.55117005
8KDM2B_26808549_Chip-Seq_SUP-B15_Human2.53955373
9KDM2B_26808549_Chip-Seq_DND41_Human2.42697755
10TCF7_22412390_ChIP-Seq_EML_Mouse2.41110299
11KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.24611924
12RUNX_20019798_ChIP-Seq_JUKART_Human2.16993874
13TP63_17297297_ChIP-ChIP_HaCaT_Human2.12385513
14KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.11428021
15STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.07444446
16* VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.98187987
17ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.93645201
18KDM2B_26808549_Chip-Seq_JURKAT_Human1.91729698
19* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.90221439
20* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.86438729
21* VDR_21846776_ChIP-Seq_THP-1_Human1.85067511
22STAT6_21828071_ChIP-Seq_BEAS2B_Human1.82964036
23* STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.77361303
24KDM2B_26808549_Chip-Seq_K562_Human1.75720813
25* MAF_26560356_Chip-Seq_TH1_Human1.67398583
26ELK3_25401928_ChIP-Seq_HUVEC_Human1.66714068
27* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.66137971
28DROSHA_22980978_ChIP-Seq_HELA_Human1.63824472
29ZFP281_27345836_Chip-Seq_ESCs_Mouse1.63260575
30WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.63033161
31* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.62840250
32IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.60606516
33RNF2_27304074_Chip-Seq_ESCs_Mouse1.58428489
34THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.58158248
35UTX_26944678_Chip-Seq_JUKART_Human1.57187794
36HIF1A_21447827_ChIP-Seq_MCF-7_Human1.49828941
37IRF8_22096565_ChIP-ChIP_GC-B_Human1.49700141
38SCL_19346495_ChIP-Seq_HPC-7_Human1.48746483
39RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.45931190
40EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.45682504
41SPI1_23127762_ChIP-Seq_K562_Human1.43840052
42* PKCTHETA_26484144_Chip-Seq_BREAST_Human1.41863255
43LXR_22292898_ChIP-Seq_THP-1_Human1.41531483
44JARID2_20075857_ChIP-Seq_MESCs_Mouse1.40348900
45KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.39906890
46* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.39905402
47JARID2_20064375_ChIP-Seq_MESCs_Mouse1.39233287
48TP53_22127205_ChIP-Seq_IMR90_Human1.39074078
49E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.38144215
50* TP53_23651856_ChIP-Seq_MEFs_Mouse1.37990238
51* VDR_24763502_ChIP-Seq_THP-1_Human1.37531319
52* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.37120302
53FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.37077917
54FOXO3_23340844_ChIP-Seq_DLD1_Human1.35941805
55TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.31304803
56GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.31151943
57* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.29159290
58SOX9_24532713_ChIP-Seq_HFSC_Mouse1.28813418
59RNF2_18974828_ChIP-Seq_MESCs_Mouse1.28800515
60EZH2_18974828_ChIP-Seq_MESCs_Mouse1.28800515
61NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.27395584
62SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.27292374
63ZFP281_18757296_ChIP-ChIP_E14_Mouse1.26886647
64RING1B_27294783_Chip-Seq_NPCs_Mouse1.25421049
65MYB_26560356_Chip-Seq_TH2_Human1.25107723
66BRD4_27068464_Chip-Seq_AML-cells_Mouse1.23911682
67MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.23609086
68EZH2_27304074_Chip-Seq_ESCs_Mouse1.23237076
69* MYB_26560356_Chip-Seq_TH1_Human1.22664466
70EZH2_27294783_Chip-Seq_ESCs_Mouse1.22643643
71* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.20496211
72ESR2_21235772_ChIP-Seq_MCF-7_Human1.20491626
73NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.20478700
74MTF2_20144788_ChIP-Seq_MESCs_Mouse1.19301318
75* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.19272662
76* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.18674585
77ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.18523510
78NFIB_24661679_ChIP-Seq_LUNG_Mouse1.18266345
79ESR1_21235772_ChIP-Seq_MCF-7_Human1.17985398
80* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.17482548
81RACK7_27058665_Chip-Seq_MCF-7_Human1.17142604
82AR_21572438_ChIP-Seq_LNCaP_Human1.16897240
83IRF8_27001747_Chip-Seq_BMDM_Mouse1.16355915
84KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.16037586
85SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.15641776
86* ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.15424538
87TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.14648437
88SMC4_20622854_ChIP-Seq_HELA_Human1.13878382
89* RUNX1_27514584_Chip-Seq_MCF-7_Human1.13102376
90MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.12617494
91* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.11710582
92AHR_22903824_ChIP-Seq_MCF-7_Human1.11098106
93SMAD_19615063_ChIP-ChIP_OVARY_Human1.10907433
94* TBX20_22080862_ChIP-Seq_HEART_Mouse1.10435242
95* TBX20_22328084_ChIP-Seq_HEART_Mouse1.10435242
96SUZ12_27294783_Chip-Seq_ESCs_Mouse1.10424443
97TP53_16413492_ChIP-PET_HCT116_Human1.10099313
98* NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.09303115
99UBF1/2_26484160_Chip-Seq_HMECs_Human1.09198664
100* VDR_24787735_ChIP-Seq_THP-1_Human1.09178061
101* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.08669944
102* FOXA2_19822575_ChIP-Seq_HepG2_Human1.07729579
103* AR_19668381_ChIP-Seq_PC3_Human1.07054119
104ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.06851369
105GATA1_19941826_ChIP-Seq_K562_Human1.06727690
106* CTNNB1_20460455_ChIP-Seq_HCT116_Human1.06433728
107OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.05546630
108SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.05361993
109SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.03772263
110ESR1_20079471_ChIP-ChIP_T-47D_Human1.03674628
111FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.02428557
112* NCOR1_26117541_ChIP-Seq_K562_Human1.01901816
113* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.01726984
114TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.01582228
115* MITF_21258399_ChIP-Seq_MELANOMA_Human1.00733128
116MYB_21317192_ChIP-Seq_ERMYB_Mouse1.00353448
117GATA1_19941827_ChIP-Seq_MEL_Mouse1.00087076
118* PPAR_26484153_Chip-Seq_NCI-H1993_Human0.99780646
119RBPJ_22232070_ChIP-Seq_NCS_Mouse0.99512692
120CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.99485851
121UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.98391339
122CREB1_26743006_Chip-Seq_LNCaP_Human0.97643483
123SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.96960191
124RXR_22108803_ChIP-Seq_LS180_Human0.96273259
125TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.95944570
126EED_16625203_ChIP-ChIP_MESCs_Mouse0.95360170
127GATA2_19941826_ChIP-Seq_K562_Human0.95288642
128RING1B_27294783_Chip-Seq_ESCs_Mouse0.95056717
129FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.94734373
130* RARB_27405468_Chip-Seq_BRAIN_Mouse0.94210020
131RARG_19884340_ChIP-ChIP_MEFs_Mouse0.92564180
132* MAF_26560356_Chip-Seq_TH2_Human0.92009499
133* ISL1_27105846_Chip-Seq_CPCs_Mouse0.91771489
134GATA2_21666600_ChIP-Seq_HMVEC_Human0.91257049
135GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90998569
136DNAJC2_21179169_ChIP-ChIP_NT2_Human0.90737570
137IKZF1_21737484_ChIP-ChIP_HCT116_Human0.90322408
138ARNT_22903824_ChIP-Seq_MCF-7_Human0.90309779
139CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.89492748

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog3.68329118
2MP0003300_gastrointestinal_ulcer3.48893875
3MP0005076_abnormal_cell_differentiation3.38003661
4MP0002009_preneoplasia3.14264254
5MP0005409_darkened_coat_color3.11603662
6MP0003303_peritoneal_inflammation3.07873252
7MP0000569_abnormal_digit_pigmentation2.74264416
8MP0004510_myositis2.67879171
9MP0008961_abnormal_basal_metabolism2.51737548
10MP0010352_gastrointestinal_tract_polyps2.42395678
11MP0003045_fibrosis2.33213718
12MP0003566_abnormal_cell_adhesion2.23462902
13MP0009278_abnormal_bone_marrow2.21416993
14MP0004185_abnormal_adipocyte_glucose2.04851533
15MP0005387_immune_system_phenotype1.95571359
16MP0001790_abnormal_immune_system1.95571359
17MP0000537_abnormal_urethra_morphology1.94826637
18MP0002396_abnormal_hematopoietic_system1.92175552
19MP0002249_abnormal_larynx_morphology1.92119087
20MP0010234_abnormal_vibrissa_follicle1.85727610
21MP0001348_abnormal_lacrimal_gland1.83874945
22MP0004808_abnormal_hematopoietic_stem1.83238470
23MP0003091_abnormal_cell_migration1.78934310
24MP0005257_abnormal_intraocular_pressure1.78299073
25MP0002166_altered_tumor_susceptibility1.76962730
26MP0003763_abnormal_thymus_physiology1.76680472
27MP0004233_abnormal_muscle_weight1.73313346
28MP0000685_abnormal_immune_system1.68320164
29* MP0000733_abnormal_muscle_development1.67166634
30MP0001800_abnormal_humoral_immune1.64238320
31MP0004947_skin_inflammation1.62361469
32MP0001502_abnormal_circadian_rhythm1.61623636
33MP0004381_abnormal_hair_follicle1.54247102
34MP0000778_abnormal_nervous_system1.52995458
35MP0000534_abnormal_ureter_morphology1.49932196
36MP0005275_abnormal_skin_tensile1.47825811
37MP0003436_decreased_susceptibility_to1.39993956
38MP0005023_abnormal_wound_healing1.39736846
39MP0002006_tumorigenesis1.39495972
40MP0001849_ear_inflammation1.37768051
41MP0003279_aneurysm1.36983686
42MP0002877_abnormal_melanocyte_morpholog1.36622788
43MP0001879_abnormal_lymphatic_vessel1.36542519
44MP0005670_abnormal_white_adipose1.36497884
45MP0008438_abnormal_cutaneous_collagen1.33446931
46MP0000751_myopathy1.30674960
47MP0002452_abnormal_antigen_presenting1.28924885
48MP0001835_abnormal_antigen_presentation1.28539632
49MP0004859_abnormal_synaptic_plasticity1.28133626
50MP0004134_abnormal_chest_morphology1.27631658
51MP0002398_abnormal_bone_marrow1.27343452
52MP0002998_abnormal_bone_remodeling1.27309899
53MP0005375_adipose_tissue_phenotype1.26494091
54MP0005623_abnormal_meninges_morphology1.26260121
55MP0000703_abnormal_thymus_morphology1.24050090
56MP0006138_congestive_heart_failure1.23064262
57MP0005666_abnormal_adipose_tissue1.20892407
58MP0003453_abnormal_keratinocyte_physiol1.19274344
59MP0010630_abnormal_cardiac_muscle1.18379321
60MP0000767_abnormal_smooth_muscle1.18111082
61MP0002168_other_aberrant_phenotype1.18103448
62MP0004130_abnormal_muscle_cell1.18042268
63MP0002108_abnormal_muscle_morphology1.17956557
64MP0002420_abnormal_adaptive_immunity1.17109008
65MP0009384_cardiac_valve_regurgitation1.16831823
66MP0000003_abnormal_adipose_tissue1.16483150
67MP0001819_abnormal_immune_cell1.15690868
68MP0005171_absent_coat_pigmentation1.15133182
69MP0003942_abnormal_urinary_system1.14853047
70MP0005645_abnormal_hypothalamus_physiol1.14571795
71MP0002925_abnormal_cardiovascular_devel1.14309222
72MP0003935_abnormal_craniofacial_develop1.13381924
73MP0002405_respiratory_system_inflammati1.13177692
74MP0001873_stomach_inflammation1.12452901
75MP0004084_abnormal_cardiac_muscle1.11566021
76MP0002723_abnormal_immune_serum1.10456296
77MP0002116_abnormal_craniofacial_bone1.10369527
78MP0003283_abnormal_digestive_organ1.09995750
79MP0000013_abnormal_adipose_tissue1.09318148
80MP0000678_abnormal_parathyroid_gland1.07708061
81MP0001545_abnormal_hematopoietic_system1.07507002
82MP0005397_hematopoietic_system_phenotyp1.07507002
83MP0005000_abnormal_immune_tolerance1.07333925
84MP0003828_pulmonary_edema1.06076070
85MP0000759_abnormal_skeletal_muscle1.06015474
86MP0000383_abnormal_hair_follicle1.05964890
87MP0003635_abnormal_synaptic_transmissio1.05633204
88MP0003115_abnormal_respiratory_system1.05205506
89MP0008057_abnormal_DNA_replication1.04901666
90MP0010307_abnormal_tumor_latency1.04239577
91MP0000716_abnormal_immune_system1.03598158
92MP0002063_abnormal_learning/memory/cond1.02099840
93MP0004272_abnormal_basement_membrane0.98958808
94MP0000428_abnormal_craniofacial_morphol0.98088249
95MP0002089_abnormal_postnatal_growth/wei0.96773755
96MP0000747_muscle_weakness0.95504389
97MP0001851_eye_inflammation0.94352911
98MP0004087_abnormal_muscle_fiber0.94002274
99MP0001299_abnormal_eye_distance/0.93871969
100MP0003329_amyloid_beta_deposits0.93588847
101MP0003252_abnormal_bile_duct0.92966508
102MP0002332_abnormal_exercise_endurance0.92277001
103MP0004270_analgesia0.91960714
104MP0004145_abnormal_muscle_electrophysio0.91834282
105MP0002722_abnormal_immune_system0.91380353
106MP0010155_abnormal_intestine_physiology0.91258356
107MP0009115_abnormal_fat_cell0.91055114
108MP0002184_abnormal_innervation0.90553517
109MP0000579_abnormal_nail_morphology0.89536289
110MP0001270_distended_abdomen0.88878409
111MP0001958_emphysema0.87842841
112MP0003385_abnormal_body_wall0.87690536
113MP0005671_abnormal_response_to0.87316954
114MP0005464_abnormal_platelet_physiology0.86788040
115MP0003448_altered_tumor_morphology0.86434743
116MP0002060_abnormal_skin_morphology0.85984075
117MP0005451_abnormal_body_composition0.85898706
118MP0009780_abnormal_chondrocyte_physiolo0.85875759
119MP0002932_abnormal_joint_morphology0.85454374
120MP0002928_abnormal_bile_duct0.85182886
121MP0001784_abnormal_fluid_regulation0.84515788
122MP0005423_abnormal_somatic_nervous0.84504072
123MP0001915_intracranial_hemorrhage0.83159257
124MP0002933_joint_inflammation0.82771331
125MP0000266_abnormal_heart_morphology0.81829886
126MP0000432_abnormal_head_morphology0.81789930
127MP0002098_abnormal_vibrissa_morphology0.80937822
128MP0005310_abnormal_salivary_gland0.80739700
129MP0003755_abnormal_palate_morphology0.80447842
130MP0000689_abnormal_spleen_morphology0.79747453
131MP0010678_abnormal_skin_adnexa0.79319481
132MP0003861_abnormal_nervous_system0.79237661
133MP0001533_abnormal_skeleton_physiology0.78939508
134MP0000955_abnormal_spinal_cord0.78872095
135MP0004197_abnormal_fetal_growth/weight/0.78825696
136MP0003172_abnormal_lysosome_physiology0.78323843
137MP0004036_abnormal_muscle_relaxation0.78070706
138MP0000762_abnormal_tongue_morphology0.77811977
139MP0010368_abnormal_lymphatic_system0.77549388
140MP0005248_abnormal_Harderian_gland0.77543782
141MP0002128_abnormal_blood_circulation0.75989614
142MP0002429_abnormal_blood_cell0.74693688
143MP0002896_abnormal_bone_mineralization0.74618010
144MP0003634_abnormal_glial_cell0.73880871
145MP0002419_abnormal_innate_immunity0.73253354
146MP0002114_abnormal_axial_skeleton0.73207155
147MP0005187_abnormal_penis_morphology0.71561935
148MP0002254_reproductive_system_inflammat0.71238748
149MP0008770_decreased_survivor_rate0.70682796
150MP0001614_abnormal_blood_vessel0.70617814
151MP0002970_abnormal_white_adipose0.70566601
152MP0002075_abnormal_coat/hair_pigmentati0.70433542
153MP0004858_abnormal_nervous_system0.70402941
154MP0003787_abnormal_imprinting0.69674878
155MP0002081_perinatal_lethality0.69577356
156MP0001216_abnormal_epidermal_layer0.69522795
157MP0002152_abnormal_brain_morphology0.69517263
158MP0003948_abnormal_gas_homeostasis0.68912043

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)3.72121379
2Broad face (HP:0000283)3.62941653
3Cerebral aneurysm (HP:0004944)3.48583474
4Obstructive sleep apnea (HP:0002870)3.45868382
5Shallow orbits (HP:0000586)2.99201814
6Macroorchidism (HP:0000053)2.80024044
7Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.79107554
8Short 4th metacarpal (HP:0010044)2.79107554
9Aortic aneurysm (HP:0004942)2.76539490
10Hyperacusis (HP:0010780)2.65994912
11Mitral valve prolapse (HP:0001634)2.62978138
12Increased density of long bones (HP:0006392)2.58791095
13Narrow palate (HP:0000189)2.41528453
14Protrusio acetabuli (HP:0003179)2.28032930
15Dysmetric saccades (HP:0000641)2.25973225
16Dilatation of the ascending aorta (HP:0005111)2.25610958
17Aneurysm (HP:0002617)2.21413862
18Broad metatarsal (HP:0001783)2.20503616
19Bronchomalacia (HP:0002780)2.18433162
20Absent frontal sinuses (HP:0002688)2.18165154
21Abnormality of the 4th metacarpal (HP:0010012)2.16267383
22Subacute progressive viral hepatitis (HP:0006572)2.16007701
23Trigonocephaly (HP:0000243)2.13964582
24Abnormality of the aortic arch (HP:0012303)2.12795363
25Spinal cord lesions (HP:0100561)2.12541108
26Syringomyelia (HP:0003396)2.12541108
27Increased IgE level (HP:0003212)2.10954491
28Long eyelashes (HP:0000527)2.09946699
29Disproportionate tall stature (HP:0001519)2.08422871
30Genu recurvatum (HP:0002816)2.07227590
31Truncal ataxia (HP:0002078)2.05026900
32Urethral obstruction (HP:0000796)2.03168507
33Aortic dissection (HP:0002647)2.01433731
34Myocardial infarction (HP:0001658)2.01212693
35Abnormality of the distal phalanx of the thumb (HP:0009617)2.00400880
36Flat cornea (HP:0007720)1.98168091
37Progressive cerebellar ataxia (HP:0002073)1.96778785
38Abnormality of the ischium (HP:0003174)1.96516290
39Impaired smooth pursuit (HP:0007772)1.95987091
40Germ cell neoplasia (HP:0100728)1.95056423
41Laryngomalacia (HP:0001601)1.95051896
42Enlarged penis (HP:0000040)1.94361026
43Megalocornea (HP:0000485)1.93641187
44Striae distensae (HP:0001065)1.93070211
45Milia (HP:0001056)1.92187791
46Aortic regurgitation (HP:0001659)1.91334310
47Ulnar bowing (HP:0003031)1.91112854
48Heterotopia (HP:0002282)1.90509869
49Frequent falls (HP:0002359)1.89444222
50Autoimmune thrombocytopenia (HP:0001973)1.88981547
51Elfin facies (HP:0004428)1.87292400
52Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.86310171
53Tented upper lip vermilion (HP:0010804)1.85847865
54Spina bifida occulta (HP:0003298)1.85426108
55Insomnia (HP:0100785)1.85210357
56Mitral stenosis (HP:0001718)1.84302584
57Tracheomalacia (HP:0002779)1.84220944
58Cellulitis (HP:0100658)1.84168555
59Vertebral arch anomaly (HP:0008438)1.83214415
60High anterior hairline (HP:0009890)1.83087392
61Patellar dislocation (HP:0002999)1.82313904
62Arterial tortuosity (HP:0005116)1.82098568
63Hematochezia (HP:0002573)1.81682474
64Advanced eruption of teeth (HP:0006288)1.80664674
65Open mouth (HP:0000194)1.80471121
66Hypoplastic ischia (HP:0003175)1.79968392
67Precocious puberty (HP:0000826)1.79853396
68Abnormality of the columella (HP:0009929)1.79466884
69Wide anterior fontanel (HP:0000260)1.78385715
70Eczematoid dermatitis (HP:0000976)1.78065224
71Tibial bowing (HP:0002982)1.77367041
72Overgrowth (HP:0001548)1.74830260
73Rectal prolapse (HP:0002035)1.74066971
74Natal tooth (HP:0000695)1.73496580
75Asymmetry of the thorax (HP:0001555)1.72919721
76Renovascular hypertension (HP:0100817)1.72422127
77Cubitus valgus (HP:0002967)1.72179202
78Spontaneous hematomas (HP:0007420)1.71641597
79Spondylolisthesis (HP:0003302)1.71606987
80Hypoplastic nipples (HP:0002557)1.71206586
81Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.71201732
82Hypopigmentation of the fundus (HP:0007894)1.70541982
83Morphological abnormality of the middle ear (HP:0008609)1.70417389
84Hypoplasia of the iris (HP:0007676)1.70155312
85Osteolytic defects of the phalanges of the hand (HP:0009771)1.70003305
86Osteolytic defects of the hand bones (HP:0009699)1.70003305
87Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.69984761
88Abnormality of oral frenula (HP:0000190)1.69914418
89Fragile skin (HP:0001030)1.69188308
90Peritonitis (HP:0002586)1.67986728
91Recurrent fungal infections (HP:0002841)1.67886971
92Hemiplegia (HP:0002301)1.67798247
93Mitral regurgitation (HP:0001653)1.67387350
94Lip pit (HP:0100267)1.67005467
95Broad thumb (HP:0011304)1.66503345
96Dislocated radial head (HP:0003083)1.66452708
97Truncal obesity (HP:0001956)1.66390865
98Hamartoma of the eye (HP:0010568)1.65938923
99Smooth philtrum (HP:0000319)1.65757163
100Genetic anticipation (HP:0003743)1.64921795
101Persistence of primary teeth (HP:0006335)1.64887129
102Recurrent viral infections (HP:0004429)1.64467535
103Clumsiness (HP:0002312)1.64188147
104Upper limb amyotrophy (HP:0009129)1.64051229
105Distal upper limb amyotrophy (HP:0007149)1.64051229
106Ankyloglossia (HP:0010296)1.63844034
107Bowing of the arm (HP:0006488)1.63739573
108Bowed forearm bones (HP:0003956)1.63739573
109Ureteral stenosis (HP:0000071)1.63711478
110Bowel diverticulosis (HP:0005222)1.63472513
111Verrucae (HP:0200043)1.63201409
112Papilloma (HP:0012740)1.63201409
113Neoplasm of the heart (HP:0100544)1.63069039
114Overriding aorta (HP:0002623)1.62718414
115Colitis (HP:0002583)1.62247872
116Chronic otitis media (HP:0000389)1.61581205
117Obsessive-compulsive behavior (HP:0000722)1.61560099
118Premature skin wrinkling (HP:0100678)1.61456527
119Subaortic stenosis (HP:0001682)1.61449859
120Abnormality of the left ventricular outflow tract (HP:0011103)1.61449859
121Gastrointestinal inflammation (HP:0004386)1.61413451
122Increased connective tissue (HP:0009025)1.61370695
123Transitional cell carcinoma of the bladder (HP:0006740)1.60735065
124Difficulty running (HP:0009046)1.60538788
125Deviation of the hallux (HP:0010051)1.60286543
126Blue irides (HP:0000635)1.59837080
127Hallux valgus (HP:0001822)1.59741007
128Vascular tortuosity (HP:0004948)1.59559061
129Oligodontia (HP:0000677)1.59478347
130Turricephaly (HP:0000262)1.59407915
131Bowel incontinence (HP:0002607)1.59397635
132Protruding tongue (HP:0010808)1.59324252
133Emphysema (HP:0002097)1.58718479
134Onion bulb formation (HP:0003383)1.58663380
135Round face (HP:0000311)1.58472606
136Sparse lateral eyebrow (HP:0005338)1.57880460
137Stereotypic behavior (HP:0000733)1.57774688
138Inflammation of the large intestine (HP:0002037)1.57734052
139Pointed chin (HP:0000307)1.56647460
140Hyporeflexia of lower limbs (HP:0002600)1.56567072
141Periodontitis (HP:0000704)1.55764051
142Hyperventilation (HP:0002883)1.55704672
143Abnormal delayed hypersensitivity skin test (HP:0002963)1.55365461
144Nasal polyposis (HP:0100582)1.55043629
145Atrophic scars (HP:0001075)1.54825934
146Uterine leiomyosarcoma (HP:0002891)1.54813842
147Leiomyosarcoma (HP:0100243)1.54813842
148Ankle contracture (HP:0006466)1.53790416
149Bladder diverticulum (HP:0000015)1.53616253
150Limited elbow extension (HP:0001377)1.53542794
151Pseudobulbar signs (HP:0002200)1.53250785
152Chest pain (HP:0100749)1.53137045
153Ureteral obstruction (HP:0006000)1.53061565
154Abnormality of the radial head (HP:0003995)1.52887053
155Gastrointestinal carcinoma (HP:0002672)1.52343672
156Malignant gastrointestinal tract tumors (HP:0006749)1.52343672
157Distal lower limb amyotrophy (HP:0008944)1.51455665
158Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.49864807
159Abnormality of the nasal septum (HP:0000419)1.49728490
160Right ventricular cardiomyopathy (HP:0011663)1.49677984

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB33.36437171
2EEF2K3.23795367
3CDK123.02291307
4MAP4K12.86590347
5SIK12.58391609
6MAP3K102.50223021
7PRPF4B2.40861008
8PKN22.37457726
9SIK22.17524557
10ERN12.03305337
11CAMK1G2.01826153
12NEK11.97510090
13SMG11.94038153
14RIPK11.89240276
15CAMK1D1.88369000
16FRK1.88181956
17LATS11.80658491
18DMPK1.77492724
19MST1R1.76530133
20TTN1.71046109
21AKT31.67511844
22EPHA21.65123387
23FGFR41.65058157
24MARK11.58817290
25SIK31.55381221
26JAK11.52610056
27STK101.50127894
28TAOK11.47421565
29JAK31.42449249
30PDGFRA1.41513884
31FGFR31.40432364
32MAP3K71.39104784
33ALK1.39056610
34LMTK21.38155802
35PTK61.38047755
36EPHB11.37353509
37PRKCH1.34931812
38TGFBR21.26494453
39ICK1.25537081
40MARK21.23951188
41MET1.16764295
42PRKD31.12924319
43BMX1.12832831
44MAPK111.12831177
45SGK31.11191107
46HCK1.08555656
47PRKD21.07821322
48* MTOR1.06423598
49MAPKAPK31.02594737
50PDGFRB1.02314338
51MELK1.02140019
52STK381.00785643
53TYK20.98801481
54LRRK20.98789301
55ITK0.98673242
56GRK60.97892939
57ZAP700.96737439
58NEK20.90195877
59CHUK0.87669805
60RET0.87356159
61CDK60.85189717
62EPHA30.84522261
63TYRO30.82817999
64BRD40.80376160
65PHKG10.78840506
66PHKG20.78840506
67MAP3K130.78283614
68PRKAA10.78130430
69FGFR20.77662098
70JAK20.75571276
71CSF1R0.75071658
72SGK4940.73936264
73SGK2230.73936264
74HIPK20.73721111
75EPHB20.73058036
76NTRK20.72651259
77CSK0.70459158
78PTK20.70049857
79STK30.69932440
80TXK0.68018908
81MAP3K90.67754860
82STK110.65592111
83RPS6KB20.65536005
84PAK20.65059853
85CAMK40.64442121
86BTK0.63122176
87CLK10.62556965
88CAMKK10.62231308
89RPS6KA60.61866572
90IRAK30.60919865
91RPS6KL10.58687756
92RPS6KC10.58687756
93PDK10.58494530
94STK390.58196745
95NEK90.57766678
96MAPK80.57005608
97PRKD10.56747482
98MAPK70.55947397
99SGK20.54375087
100SYK0.52896825
101MAPKAPK50.52776988
102RPS6KA20.51489666
103FER0.50511831
104MAP2K20.50455544
105RPS6KB10.49642702
106NLK0.49487503
107MARK30.48992072
108CDK90.48695861
109FGFR10.48563307
110NEK60.48050383
111NTRK10.47782362
112MAPK100.46450633
113PTK2B0.45754165
114DDR20.45376506
115CDC42BPA0.45327488
116LATS20.44952165
117PAK60.44258782
118PRKCQ0.43775601
119WNK10.42991048
120MAP3K140.42898051
121ERBB20.42293040
122LCK0.42147254
123RIPK40.41521994
124FES0.41470615
125RPS6KA40.41436851
126KSR10.40935712
127TNK20.39896734
128CDK40.39822356
129TAOK30.39203683
130RPS6KA10.39031163
131PDPK10.38822550
132MAPK10.38821290
133CAMK10.38687660
134GSK3B0.38158782
135PRKAA20.37722940
136MAP2K10.37669741
137MAPK120.37241647
138IKBKE0.37223260
139TRPM70.36552639
140CASK0.35697163

Predicted pathways (KEGG)

RankGene SetZ-score
1Chronic myeloid leukemia_Homo sapiens_hsa052201.79566225
2B cell receptor signaling pathway_Homo sapiens_hsa046621.61328701
3Osteoclast differentiation_Homo sapiens_hsa043801.44193332
4Nitrogen metabolism_Homo sapiens_hsa009101.43506969
5T cell receptor signaling pathway_Homo sapiens_hsa046601.42328464
6Lysine degradation_Homo sapiens_hsa003101.41946258
7Non-small cell lung cancer_Homo sapiens_hsa052231.35755556
8mTOR signaling pathway_Homo sapiens_hsa041501.33344863
9Acute myeloid leukemia_Homo sapiens_hsa052211.32508998
10Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.32141079
11Glioma_Homo sapiens_hsa052141.31988464
12Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.31859758
13Pancreatic cancer_Homo sapiens_hsa052121.31423370
14Dorso-ventral axis formation_Homo sapiens_hsa043201.31181523
15AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.29369052
16Adherens junction_Homo sapiens_hsa045201.25452298
17Neurotrophin signaling pathway_Homo sapiens_hsa047221.23914021
18Inositol phosphate metabolism_Homo sapiens_hsa005621.22889850
19Proteoglycans in cancer_Homo sapiens_hsa052051.21705888
20Type II diabetes mellitus_Homo sapiens_hsa049301.21189270
21Thyroid hormone signaling pathway_Homo sapiens_hsa049191.17769643
22Primary immunodeficiency_Homo sapiens_hsa053401.17182517
23Endometrial cancer_Homo sapiens_hsa052131.16793732
24Insulin resistance_Homo sapiens_hsa049311.15940449
25Circadian entrainment_Homo sapiens_hsa047131.15333721
26Toxoplasmosis_Homo sapiens_hsa051451.14058959
27Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.13892586
28Axon guidance_Homo sapiens_hsa043601.13196728
29Notch signaling pathway_Homo sapiens_hsa043301.12641987
30Viral myocarditis_Homo sapiens_hsa054161.11925872
31MicroRNAs in cancer_Homo sapiens_hsa052061.11243888
32Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.11089985
33Focal adhesion_Homo sapiens_hsa045101.11061790
34Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.08670236
35VEGF signaling pathway_Homo sapiens_hsa043701.06440482
36Renal cell carcinoma_Homo sapiens_hsa052111.05794431
37Leishmaniasis_Homo sapiens_hsa051401.05634485
38Leukocyte transendothelial migration_Homo sapiens_hsa046701.05142794
39Small cell lung cancer_Homo sapiens_hsa052221.05022600
40Colorectal cancer_Homo sapiens_hsa052101.04201332
41Hippo signaling pathway_Homo sapiens_hsa043901.04186045
42Chemokine signaling pathway_Homo sapiens_hsa040621.02999562
43Platelet activation_Homo sapiens_hsa046111.02555820
44Prolactin signaling pathway_Homo sapiens_hsa049171.02221409
45Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.01757951
46Aldosterone synthesis and secretion_Homo sapiens_hsa049251.01711128
47Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.01448813
48ErbB signaling pathway_Homo sapiens_hsa040121.00910109
49Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.00090170
50Glutamatergic synapse_Homo sapiens_hsa047240.99252684
51Estrogen signaling pathway_Homo sapiens_hsa049150.98100133
52Hepatitis B_Homo sapiens_hsa051610.96928513
53Amoebiasis_Homo sapiens_hsa051460.94267009
54Longevity regulating pathway - mammal_Homo sapiens_hsa042110.93578334
55Dilated cardiomyopathy_Homo sapiens_hsa054140.93439160
56Phosphatidylinositol signaling system_Homo sapiens_hsa040700.93199802
57Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.92655910
58Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.92419342
59Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.92234732
60Morphine addiction_Homo sapiens_hsa050320.90838514
61NF-kappa B signaling pathway_Homo sapiens_hsa040640.90080236
62Melanogenesis_Homo sapiens_hsa049160.90056907
63Melanoma_Homo sapiens_hsa052180.89869475
64Long-term depression_Homo sapiens_hsa047300.89735027
65Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.89626856
66Thyroid cancer_Homo sapiens_hsa052160.89091895
67Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.88915286
68Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.88660118
69Calcium signaling pathway_Homo sapiens_hsa040200.86824825
70Measles_Homo sapiens_hsa051620.86693796
71Insulin secretion_Homo sapiens_hsa049110.86518807
72Regulation of actin cytoskeleton_Homo sapiens_hsa048100.86412748
73Rap1 signaling pathway_Homo sapiens_hsa040150.85864148
74TNF signaling pathway_Homo sapiens_hsa046680.85551940
75Circadian rhythm_Homo sapiens_hsa047100.84781948
76Adipocytokine signaling pathway_Homo sapiens_hsa049200.83674307
77Jak-STAT signaling pathway_Homo sapiens_hsa046300.83539525
78Carbohydrate digestion and absorption_Homo sapiens_hsa049730.82857289
79Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.82742241
80MAPK signaling pathway_Homo sapiens_hsa040100.82626942
81cGMP-PKG signaling pathway_Homo sapiens_hsa040220.81971278
82Prostate cancer_Homo sapiens_hsa052150.81933685
83Toll-like receptor signaling pathway_Homo sapiens_hsa046200.81618910
84Phospholipase D signaling pathway_Homo sapiens_hsa040720.80889179
85Vascular smooth muscle contraction_Homo sapiens_hsa042700.80453991
86Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.80288363
87Gastric acid secretion_Homo sapiens_hsa049710.80151554
88HTLV-I infection_Homo sapiens_hsa051660.79687031
89Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.78812604
90FoxO signaling pathway_Homo sapiens_hsa040680.78556383
91ABC transporters_Homo sapiens_hsa020100.77949114
92Insulin signaling pathway_Homo sapiens_hsa049100.76675202
93Staphylococcus aureus infection_Homo sapiens_hsa051500.76216538
94Oxytocin signaling pathway_Homo sapiens_hsa049210.75996444
95Long-term potentiation_Homo sapiens_hsa047200.75386078
96Ras signaling pathway_Homo sapiens_hsa040140.75198587
97Ovarian steroidogenesis_Homo sapiens_hsa049130.75177011
98GnRH signaling pathway_Homo sapiens_hsa049120.74844841
99Choline metabolism in cancer_Homo sapiens_hsa052310.74708855
100Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.73926343
101Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.72818180
102Central carbon metabolism in cancer_Homo sapiens_hsa052300.72705736
103ECM-receptor interaction_Homo sapiens_hsa045120.72384679
104Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.70866189
105Hedgehog signaling pathway_Homo sapiens_hsa043400.70381283
106HIF-1 signaling pathway_Homo sapiens_hsa040660.70372139
107Gap junction_Homo sapiens_hsa045400.69925682
108Salivary secretion_Homo sapiens_hsa049700.69341846
109Renin secretion_Homo sapiens_hsa049240.69234516
110Tuberculosis_Homo sapiens_hsa051520.69133320
111Alcoholism_Homo sapiens_hsa050340.67121319
112Pathways in cancer_Homo sapiens_hsa052000.66771918
113cAMP signaling pathway_Homo sapiens_hsa040240.66386110
114Dopaminergic synapse_Homo sapiens_hsa047280.65588070
115Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.65472557
116Glucagon signaling pathway_Homo sapiens_hsa049220.65375835
117Cholinergic synapse_Homo sapiens_hsa047250.64620068
118Wnt signaling pathway_Homo sapiens_hsa043100.64123525
119Olfactory transduction_Homo sapiens_hsa047400.64052895
120Nicotine addiction_Homo sapiens_hsa050330.63927927
121Sphingolipid signaling pathway_Homo sapiens_hsa040710.63802243
122Bladder cancer_Homo sapiens_hsa052190.63422328
123Basal cell carcinoma_Homo sapiens_hsa052170.63338725
124Intestinal immune network for IgA production_Homo sapiens_hsa046720.62975889
125Influenza A_Homo sapiens_hsa051640.62457707
126Hematopoietic cell lineage_Homo sapiens_hsa046400.62380057
127AMPK signaling pathway_Homo sapiens_hsa041520.62330178
128Endocytosis_Homo sapiens_hsa041440.61256303
129Transcriptional misregulation in cancer_Homo sapiens_hsa052020.61051702
130Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.59367760

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