FIGN

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)7.21643433
2central nervous system myelination (GO:0022010)7.21643433
3limb bud formation (GO:0060174)5.90924889
4presynaptic membrane assembly (GO:0097105)5.26383780
5cerebral cortex radially oriented cell migration (GO:0021799)5.09224422
6negative regulation of neurotransmitter secretion (GO:0046929)4.83328328
7presynaptic membrane organization (GO:0097090)4.81510623
8myelination (GO:0042552)4.80692346
9axon ensheathment (GO:0008366)4.77602381
10ensheathment of neurons (GO:0007272)4.77602381
11fatty acid elongation (GO:0030497)4.58355061
12myelination in peripheral nervous system (GO:0022011)4.27317401
13peripheral nervous system axon ensheathment (GO:0032292)4.27317401
14long-chain fatty acid biosynthetic process (GO:0042759)4.23693696
15glycerophospholipid catabolic process (GO:0046475)4.09251967
16neuron cell-cell adhesion (GO:0007158)4.07355649
17negative regulation of neurotransmitter transport (GO:0051589)4.03087416
18negative regulation of protein localization to cell surface (GO:2000009)3.97013063
19photoreceptor cell differentiation (GO:0046530)3.96693807
20eye photoreceptor cell differentiation (GO:0001754)3.96693807
21short-term memory (GO:0007614)3.85689488
22oligodendrocyte differentiation (GO:0048709)3.80259782
23lateral sprouting from an epithelium (GO:0060601)3.72718859
24isoprenoid biosynthetic process (GO:0008299)3.72210840
25regulation of pigment cell differentiation (GO:0050932)3.72061833
26retinal ganglion cell axon guidance (GO:0031290)3.61528308
27regulation of collateral sprouting (GO:0048670)3.60740072
28astrocyte development (GO:0014002)3.47792267
29forebrain neuron development (GO:0021884)3.44602752
30cholesterol biosynthetic process (GO:0006695)3.42915539
31retina layer formation (GO:0010842)3.35625423
32mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.33626198
33postsynaptic membrane organization (GO:0001941)3.30193168
34chromatin remodeling at centromere (GO:0031055)3.23862905
35sympathetic nervous system development (GO:0048485)3.18419656
36positive regulation of action potential (GO:0045760)3.18023656
37spinal cord motor neuron differentiation (GO:0021522)3.15996723
38axonal fasciculation (GO:0007413)3.08088184
39somite development (GO:0061053)3.05536620
40import into cell (GO:0098657)3.04662845
41positive regulation of synapse assembly (GO:0051965)3.02089873
42kinetochore organization (GO:0051383)3.02070984
43organ growth (GO:0035265)2.96085537
44substantia nigra development (GO:0021762)2.95441146
45mesonephros development (GO:0001823)2.94678703
46cerebral cortex cell migration (GO:0021795)2.94331329
47CENP-A containing nucleosome assembly (GO:0034080)2.93651961
48negative regulation of axon extension (GO:0030517)2.93624823
49kinetochore assembly (GO:0051382)2.93622433
50negative regulation of execution phase of apoptosis (GO:1900118)2.92489511
51cranial nerve morphogenesis (GO:0021602)2.91991435
52intraciliary transport (GO:0042073)2.91266074
53regulation of somitogenesis (GO:0014807)2.89744587
54epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.88533132
55transmission of nerve impulse (GO:0019226)2.88464140
56protein neddylation (GO:0045116)2.87976961
57negative regulation of axon extension involved in axon guidance (GO:0048843)2.86558227
58DNA integration (GO:0015074)2.85697350
59mesenchymal cell differentiation involved in kidney development (GO:0072161)2.85088067
60mesenchymal cell differentiation involved in renal system development (GO:2001012)2.85088067
61neuron recognition (GO:0008038)2.84963226
62female gonad development (GO:0008585)2.84261370
63nucleobase catabolic process (GO:0046113)2.84129773
64cyclic nucleotide catabolic process (GO:0009214)2.83619856
65peripheral nervous system development (GO:0007422)2.82902719
66DNA double-strand break processing (GO:0000729)2.82178880
67enteric nervous system development (GO:0048484)2.82092977
68sterol biosynthetic process (GO:0016126)2.81621682
69establishment of mitochondrion localization (GO:0051654)2.80181134
70nonmotile primary cilium assembly (GO:0035058)2.79733652
71negative regulation of myoblast differentiation (GO:0045662)2.78315610
72olfactory bulb development (GO:0021772)2.76746282
73negative regulation of axon guidance (GO:1902668)2.76427591
74otic vesicle formation (GO:0030916)2.76229686
75kidney morphogenesis (GO:0060993)2.75825107
76regulation of synapse assembly (GO:0051963)2.75010634
77cell proliferation in forebrain (GO:0021846)2.74510776
78positive regulation of gastrulation (GO:2000543)2.74060815
79neuron fate determination (GO:0048664)2.70098166
80cardiac chamber formation (GO:0003207)2.69683506
81limb development (GO:0060173)2.68868947
82appendage development (GO:0048736)2.68868947
83head development (GO:0060322)2.68770360
84neuronal stem cell maintenance (GO:0097150)2.68688035
85axon extension involved in axon guidance (GO:0048846)2.68650675
86neuron projection extension involved in neuron projection guidance (GO:1902284)2.68650675
87apical protein localization (GO:0045176)2.68373438
88microtubule polymerization or depolymerization (GO:0031109)2.67526164
89resolution of meiotic recombination intermediates (GO:0000712)2.66436461
90regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.66297824
91cell differentiation in spinal cord (GO:0021515)2.66077303
92regulation of non-canonical Wnt signaling pathway (GO:2000050)2.65604453
93cardiac ventricle formation (GO:0003211)2.64737962
94neural nucleus development (GO:0048857)2.64494379
95cell differentiation involved in kidney development (GO:0061005)2.63646501
96membrane assembly (GO:0071709)2.63389026
97cell differentiation involved in metanephros development (GO:0072202)2.63388819
98adult walking behavior (GO:0007628)2.62211854
99positive regulation of oligodendrocyte differentiation (GO:0048714)2.61419076
100ATP synthesis coupled proton transport (GO:0015986)2.60250854
101energy coupled proton transport, down electrochemical gradient (GO:0015985)2.60250854
102protein localization to synapse (GO:0035418)2.60156355
103regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.58162847
104dendritic spine morphogenesis (GO:0060997)2.57792676
105epithelial cilium movement (GO:0003351)2.57607652
106negative regulation of axonogenesis (GO:0050771)2.57185703
107paraxial mesoderm development (GO:0048339)2.57161813
108heme transport (GO:0015886)2.55420216
109pyrimidine nucleobase catabolic process (GO:0006208)2.55389891
110central nervous system neuron axonogenesis (GO:0021955)2.53411324
111histone exchange (GO:0043486)2.52702796
112response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.51590597
113negative regulation of multicellular organism growth (GO:0040015)2.51500388
114dendrite development (GO:0016358)2.50990481
115mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.50545146
116nucleotide transmembrane transport (GO:1901679)2.46383235
117somite rostral/caudal axis specification (GO:0032525)2.46260290
118L-amino acid import (GO:0043092)2.45708457
119dorsal/ventral axis specification (GO:0009950)2.45691089
120response to redox state (GO:0051775)2.45663132
121replication fork processing (GO:0031297)2.45016589
122DNA damage response, detection of DNA damage (GO:0042769)2.43924324
123glial cell development (GO:0021782)2.43414630
124forebrain neuron differentiation (GO:0021879)2.43359145
125positive regulation of meiosis (GO:0045836)2.43321084
126regulation of respiratory system process (GO:0044065)2.41756324
127metaphase plate congression (GO:0051310)2.39771623
128central nervous system projection neuron axonogenesis (GO:0021952)2.39461046
129microtubule depolymerization (GO:0007019)2.38994602
130cranial nerve structural organization (GO:0021604)2.38140135
131negative chemotaxis (GO:0050919)2.37619881
132negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.37487140
133cranial nerve development (GO:0021545)2.37400507
134DNA replication-independent nucleosome organization (GO:0034724)2.36886376
135DNA replication-independent nucleosome assembly (GO:0006336)2.36886376
136pancreas development (GO:0031016)2.35411014
137negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.34658807
138negative regulation of translation, ncRNA-mediated (GO:0040033)2.34658807
139regulation of translation, ncRNA-mediated (GO:0045974)2.34658807
140protein localization to kinetochore (GO:0034501)2.34143816
141hindbrain development (GO:0030902)2.32601532
142pituitary gland development (GO:0021983)2.32516709
143cilium organization (GO:0044782)2.31964165
144cilium assembly (GO:0042384)2.31888756
145smoothened signaling pathway (GO:0007224)2.30920635
146thalamus development (GO:0021794)2.30889801
147cilium morphogenesis (GO:0060271)2.28281929
148calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.27475834
149positive regulation of neuroblast proliferation (GO:0002052)2.27128554
150auditory behavior (GO:0031223)2.25578964
151neurotransmitter-gated ion channel clustering (GO:0072578)2.25333974
152establishment of tissue polarity (GO:0007164)2.24989742
153establishment of planar polarity (GO:0001736)2.24989742
154mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.24925468
155negative regulation of astrocyte differentiation (GO:0048712)2.24607002
156behavioral response to nicotine (GO:0035095)2.22419044
157G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.21657166
158DNA strand renaturation (GO:0000733)2.20387075
159mitotic metaphase plate congression (GO:0007080)2.19375699
160regulation of development, heterochronic (GO:0040034)2.18696392
161negative regulation of glial cell differentiation (GO:0045686)2.18691453
162cilium movement (GO:0003341)2.17042013
163artery development (GO:0060840)2.16864988
164ephrin receptor signaling pathway (GO:0048013)2.16584385
165establishment of protein localization to mitochondrial membrane (GO:0090151)2.15415376
166spinal cord development (GO:0021510)2.15387637
167regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.14448421
168outer ear morphogenesis (GO:0042473)2.13648360
169determination of left/right symmetry (GO:0007368)2.13631670
170generation of neurons (GO:0048699)2.13529616
171protein localization to cilium (GO:0061512)2.13140017
172G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.11367151
173spinal cord association neuron differentiation (GO:0021527)2.11178691
174protein polyglutamylation (GO:0018095)2.11042461
175synapse assembly (GO:0007416)2.08075733
176centriole replication (GO:0007099)2.07931274
177determination of bilateral symmetry (GO:0009855)2.07382571
178dorsal/ventral pattern formation (GO:0009953)2.06620871

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.97670029
2GBX2_23144817_ChIP-Seq_PC3_Human3.67099526
3GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.75442364
4EZH2_27304074_Chip-Seq_ESCs_Mouse2.71841663
5* JARID2_20064375_ChIP-Seq_MESCs_Mouse2.67019984
6EED_16625203_ChIP-ChIP_MESCs_Mouse2.52608796
7CBX2_27304074_Chip-Seq_ESCs_Mouse2.47766875
8ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.47544386
9ZFP57_27257070_Chip-Seq_ESCs_Mouse2.43906160
10SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.43138768
11VDR_22108803_ChIP-Seq_LS180_Human2.42271362
12* TAF15_26573619_Chip-Seq_HEK293_Human2.41575486
13PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.38339839
14SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.36457015
15* BMI1_23680149_ChIP-Seq_NPCS_Mouse2.30736547
16RNF2_18974828_ChIP-Seq_MESCs_Mouse2.27610410
17EZH2_18974828_ChIP-Seq_MESCs_Mouse2.27610410
18SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.24069980
19WT1_19549856_ChIP-ChIP_CCG9911_Human2.18310827
20TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.14540795
21SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.13215333
22SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.09185555
23JARID2_20075857_ChIP-Seq_MESCs_Mouse2.07751230
24POU3F2_20337985_ChIP-ChIP_501MEL_Human2.04874416
25* CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.02800494
26IGF1R_20145208_ChIP-Seq_DFB_Human2.02054601
27HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.00705472
28* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.99627966
29* EZH2_27294783_Chip-Seq_ESCs_Mouse1.92801878
30MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.86564159
31* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.82143078
32* P300_19829295_ChIP-Seq_ESCs_Human1.81915236
33* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.81629767
34RNF2_27304074_Chip-Seq_ESCs_Mouse1.80335602
35FUS_26573619_Chip-Seq_HEK293_Human1.79925657
36ER_23166858_ChIP-Seq_MCF-7_Human1.76110427
37GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.74286385
38* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.73347560
39FOXM1_23109430_ChIP-Seq_U2OS_Human1.71604804
40* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.69670144
41SMAD3_21741376_ChIP-Seq_EPCs_Human1.68155243
42PCGF2_27294783_Chip-Seq_ESCs_Mouse1.65533772
43RNF2_27304074_Chip-Seq_NSC_Mouse1.65347027
44* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.65287218
45CTBP2_25329375_ChIP-Seq_LNCAP_Human1.64650818
46IRF1_19129219_ChIP-ChIP_H3396_Human1.63757061
47* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.57607175
48POU5F1_16153702_ChIP-ChIP_HESCs_Human1.56625463
49CTBP1_25329375_ChIP-Seq_LNCAP_Human1.55460606
50CDX2_19796622_ChIP-Seq_MESCs_Mouse1.50648599
51SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.47620477
52FLI1_27457419_Chip-Seq_LIVER_Mouse1.47528009
53PIAS1_25552417_ChIP-Seq_VCAP_Human1.47007595
54* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.46292012
55E2F4_17652178_ChIP-ChIP_JURKAT_Human1.45326593
56EWS_26573619_Chip-Seq_HEK293_Human1.44461391
57TP63_19390658_ChIP-ChIP_HaCaT_Human1.44271682
58AR_21572438_ChIP-Seq_LNCaP_Human1.44148650
59SOX2_16153702_ChIP-ChIP_HESCs_Human1.41148656
60TOP2B_26459242_ChIP-Seq_MCF-7_Human1.40668430
61* NANOG_18555785_Chip-Seq_ESCs_Mouse1.40439167
62* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.39651709
63E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.38479329
64PCGF2_27294783_Chip-Seq_NPCs_Mouse1.37561364
65* SMAD4_21799915_ChIP-Seq_A2780_Human1.36298452
66* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.35598921
67HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.35490748
68KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.34537207
69SUZ12_27294783_Chip-Seq_NPCs_Mouse1.34005029
70* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.33711486
71* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.31399254
72EZH2_27294783_Chip-Seq_NPCs_Mouse1.30640837
73* SUZ12_18555785_Chip-Seq_ESCs_Mouse1.28767679
74NFE2_27457419_Chip-Seq_LIVER_Mouse1.26976054
75TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26969692
76KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.26656256
77E2F1_18555785_Chip-Seq_ESCs_Mouse1.25290787
78NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.24408824
79ZNF274_21170338_ChIP-Seq_K562_Hela1.24369680
80* P53_22387025_ChIP-Seq_ESCs_Mouse1.24270349
81CMYC_18555785_Chip-Seq_ESCs_Mouse1.23747811
82AR_25329375_ChIP-Seq_VCAP_Human1.21785459
83* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.21563080
84* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.20550683
85P300_18555785_Chip-Seq_ESCs_Mouse1.19861865
86TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.18652049
87SALL1_21062744_ChIP-ChIP_HESCs_Human1.18413634
88* SOX9_26525672_Chip-Seq_HEART_Mouse1.18195918
89TAL1_26923725_Chip-Seq_HPCs_Mouse1.18027937
90* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.17575879
91NANOG_16153702_ChIP-ChIP_HESCs_Human1.15446709
92* TP53_18474530_ChIP-ChIP_U2OS_Human1.14057208
93* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.13629598
94REST_21632747_ChIP-Seq_MESCs_Mouse1.13423238
95HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.13314979
96STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.13246390
97RBPJ_22232070_ChIP-Seq_NCS_Mouse1.12501949
98BCAT_22108803_ChIP-Seq_LS180_Human1.11984393
99TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10575830
100POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.10575830
101CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10367702
102LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09312326
103* RUNX2_22187159_ChIP-Seq_PCA_Human1.09198228
104TBX3_20139965_ChIP-Seq_MESCs_Mouse1.09130736
105RING1B_27294783_Chip-Seq_NPCs_Mouse1.08309519
106* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.08023175
107ELK1_19687146_ChIP-ChIP_HELA_Human1.07714226
108TBX3_20139965_ChIP-Seq_ESCs_Mouse1.07578841
109* STAT3_18555785_Chip-Seq_ESCs_Mouse1.07089315
110* TCF4_23295773_ChIP-Seq_U87_Human1.07062148
111ESR1_20079471_ChIP-ChIP_T-47D_Human1.06972855
112* EP300_21415370_ChIP-Seq_HL-1_Mouse1.06806205
113CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.05852453
114CBP_20019798_ChIP-Seq_JUKART_Human1.05543763
115IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.05543763
116RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.05538528
117MYC_18940864_ChIP-ChIP_HL60_Human1.05405737
118KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.04651536
119* SOX2_18555785_Chip-Seq_ESCs_Mouse1.04647935
120RING1B_27294783_Chip-Seq_ESCs_Mouse1.04295431
121* RUNX1_27457419_Chip-Seq_LIVER_Mouse1.04203324
122TCF4_22108803_ChIP-Seq_LS180_Human1.03391944
123STAT3_23295773_ChIP-Seq_U87_Human1.03265555
124TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.02880941
125CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.02690240
126CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.01656875
127GATA1_26923725_Chip-Seq_HPCs_Mouse1.01625797
128* NMYC_18555785_Chip-Seq_ESCs_Mouse1.00800139
129FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.00519625
130FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.99380999
131* KDM2B_26808549_Chip-Seq_REH_Human0.98129884

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.10014879
2MP0003136_yellow_coat_color3.59070229
3MP0000566_synostosis3.55299889
4MP0001529_abnormal_vocalization3.08506548
5MP0000920_abnormal_myelination3.02301633
6MP0005171_absent_coat_pigmentation2.75018663
7MP0006292_abnormal_olfactory_placode2.70884002
8MP0004742_abnormal_vestibular_system2.46867539
9MP0000778_abnormal_nervous_system2.42206885
10MP0005409_darkened_coat_color2.32312105
11MP0001293_anophthalmia2.23114834
12MP0003890_abnormal_embryonic-extraembry2.14803779
13MP0002102_abnormal_ear_morphology2.11488877
14MP0004381_abnormal_hair_follicle2.09168778
15MP0003950_abnormal_plasma_membrane1.99222053
16MP0003938_abnormal_ear_development1.94985690
17MP0002938_white_spotting1.90499799
18* MP0001486_abnormal_startle_reflex1.87952194
19MP0006276_abnormal_autonomic_nervous1.87922310
20MP0001188_hyperpigmentation1.85221769
21MP0003122_maternal_imprinting1.82943008
22MP0003937_abnormal_limbs/digits/tail_de1.74878215
23MP0004142_abnormal_muscle_tone1.74736987
24MP0004270_analgesia1.73104736
25MP0003385_abnormal_body_wall1.71839666
26MP0001905_abnormal_dopamine_level1.65839654
27MP0002272_abnormal_nervous_system1.63825542
28MP0003121_genomic_imprinting1.63421046
29MP0003119_abnormal_digestive_system1.62062313
30MP0002234_abnormal_pharynx_morphology1.61176139
31* MP0009250_abnormal_appendicular_skeleto1.60636542
32MP0001485_abnormal_pinna_reflex1.58030825
33MP0003787_abnormal_imprinting1.56544505
34MP0005423_abnormal_somatic_nervous1.54717456
35MP0002653_abnormal_ependyma_morphology1.53710409
36MP0008789_abnormal_olfactory_epithelium1.53052919
37MP0006072_abnormal_retinal_apoptosis1.53052670
38* MP0000026_abnormal_inner_ear1.51636586
39* MP0001286_abnormal_eye_development1.50230600
40MP0009379_abnormal_foot_pigmentation1.49186897
41MP0005645_abnormal_hypothalamus_physiol1.49003028
42* MP0002697_abnormal_eye_size1.47749499
43MP0003690_abnormal_glial_cell1.46722203
44MP0002734_abnormal_mechanical_nocicepti1.44266429
45MP0009046_muscle_twitch1.43281405
46MP0002751_abnormal_autonomic_nervous1.41620111
47MP0008260_abnormal_autophagy1.40693506
48MP0002163_abnormal_gland_morphology1.39349650
49MP0009745_abnormal_behavioral_response1.36297876
50MP0008877_abnormal_DNA_methylation1.34982187
51MP0002752_abnormal_somatic_nervous1.34379140
52MP0002184_abnormal_innervation1.31993970
53MP0000762_abnormal_tongue_morphology1.31870807
54MP0000049_abnormal_middle_ear1.29168480
55MP0000631_abnormal_neuroendocrine_gland1.29031924
56MP0003567_abnormal_fetal_cardiomyocyte1.27103300
57MP0002882_abnormal_neuron_morphology1.26772593
58MP0002067_abnormal_sensory_capabilities1.26734450
59MP0002249_abnormal_larynx_morphology1.25469488
60MP0009053_abnormal_anal_canal1.25191301
61MP0005451_abnormal_body_composition1.23983885
62MP0003634_abnormal_glial_cell1.22356049
63MP0004859_abnormal_synaptic_plasticity1.22112398
64MP0000537_abnormal_urethra_morphology1.20578774
65MP0002064_seizures1.19085762
66MP0005394_taste/olfaction_phenotype1.16925805
67MP0005499_abnormal_olfactory_system1.16925805
68MP0000015_abnormal_ear_pigmentation1.15150675
69MP0005377_hearing/vestibular/ear_phenot1.14531534
70MP0003878_abnormal_ear_physiology1.14531534
71* MP0001963_abnormal_hearing_physiology1.14324190
72MP0001968_abnormal_touch/_nociception1.12442864
73MP0001984_abnormal_olfaction1.12253235
74MP0005551_abnormal_eye_electrophysiolog1.11974967
75* MP0003755_abnormal_palate_morphology1.11686277
76MP0005391_vision/eye_phenotype1.11520412
77MP0001727_abnormal_embryo_implantation1.11222109
78MP0000569_abnormal_digit_pigmentation1.11173149
79MP0005386_behavior/neurological_phenoty1.10712999
80MP0004924_abnormal_behavior1.10712999
81* MP0005248_abnormal_Harderian_gland1.10197521
82MP0002177_abnormal_outer_ear1.09956193
83MP0003137_abnormal_impulse_conducting1.08496695
84MP0003941_abnormal_skin_development1.06725868
85MP0003635_abnormal_synaptic_transmissio1.06310889
86MP0002837_dystrophic_cardiac_calcinosis1.04317124
87MP0003283_abnormal_digestive_organ1.04233786
88MP0002233_abnormal_nose_morphology1.03893750
89MP0005187_abnormal_penis_morphology1.03716637
90MP0002572_abnormal_emotion/affect_behav1.02045180
91MP0000955_abnormal_spinal_cord1.01457171
92* MP0002557_abnormal_social/conspecific_i1.00788678
93MP0004215_abnormal_myocardial_fiber0.99901177
94MP0009697_abnormal_copulation0.99603958
95MP0000428_abnormal_craniofacial_morphol0.99003261
96MP0010030_abnormal_orbit_morphology0.97677456
97MP0002229_neurodegeneration0.96867943
98MP0001440_abnormal_grooming_behavior0.95914295
99* MP0003861_abnormal_nervous_system0.95372224
100MP0008058_abnormal_DNA_repair0.94668718
101MP0002277_abnormal_respiratory_mucosa0.94043318
102MP0005379_endocrine/exocrine_gland_phen0.92976151
103* MP0002152_abnormal_brain_morphology0.92854145
104MP0000579_abnormal_nail_morphology0.92625262
105MP0002084_abnormal_developmental_patter0.92282976
106MP0002092_abnormal_eye_morphology0.91626188
107MP0008932_abnormal_embryonic_tissue0.90618567
108MP0002111_abnormal_tail_morphology0.90563763
109MP0002063_abnormal_learning/memory/cond0.89353548
110MP0000534_abnormal_ureter_morphology0.89312626
111MP0002736_abnormal_nociception_after0.89256259
112MP0002638_abnormal_pupillary_reflex0.87909667
113MP0000749_muscle_degeneration0.86822118
114MP0000462_abnormal_digestive_system0.86821522
115MP0002282_abnormal_trachea_morphology0.85610607
116* MP0005195_abnormal_posterior_eye0.85383743
117MP0003942_abnormal_urinary_system0.85353592
118MP0005646_abnormal_pituitary_gland0.85053985
119MP0004133_heterotaxia0.81365533
120MP0000383_abnormal_hair_follicle0.81218407
121* MP0002066_abnormal_motor_capabilities/c0.81076556
122MP0001177_atelectasis0.77587996
123MP0003315_abnormal_perineum_morphology0.77164059
124MP0002735_abnormal_chemical_nociception0.77028719
125* MP0002116_abnormal_craniofacial_bone0.76527707
126MP0001299_abnormal_eye_distance/0.76344535
127MP0004085_abnormal_heartbeat0.75681671
128MP0005253_abnormal_eye_physiology0.74964608
129MP0000372_irregular_coat_pigmentation0.74701076
130MP0003935_abnormal_craniofacial_develop0.73950428
131MP0004885_abnormal_endolymph0.73484317

Predicted human phenotypes

RankGene SetZ-score
1Parakeratosis (HP:0001036)4.83325930
2Degeneration of the lateral corticospinal tracts (HP:0002314)4.81025380
3Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.81025380
4Alacrima (HP:0000522)3.84552938
5Decreased lacrimation (HP:0000633)3.44922594
6Abnormality of the corticospinal tract (HP:0002492)3.43729248
7Septo-optic dysplasia (HP:0100842)3.37258038
8Absent septum pellucidum (HP:0001331)3.30433608
9Acute necrotizing encephalopathy (HP:0006965)3.20633482
10Partial duplication of thumb phalanx (HP:0009944)3.08334763
11Intestinal atresia (HP:0011100)3.04756625
12Abnormality of the septum pellucidum (HP:0007375)2.95312855
13Sensory axonal neuropathy (HP:0003390)2.89904784
14Colon cancer (HP:0003003)2.88941932
15Hypoplastic left heart (HP:0004383)2.86717054
16Adrenal hypoplasia (HP:0000835)2.84561580
17Pancreatic fibrosis (HP:0100732)2.84046841
18Chronic hepatic failure (HP:0100626)2.83834469
19Abnormality of midbrain morphology (HP:0002418)2.76434665
20Molar tooth sign on MRI (HP:0002419)2.76434665
21Partial duplication of the phalanx of hand (HP:0009999)2.76383472
22Steppage gait (HP:0003376)2.75023219
23Anomalous pulmonary venous return (HP:0010772)2.73939120
24Abnormality of the labia minora (HP:0012880)2.72463567
25Progressive macrocephaly (HP:0004481)2.68966138
26Nephronophthisis (HP:0000090)2.68730946
27Abnormality of incisor morphology (HP:0011063)2.68067801
28Oligodactyly (hands) (HP:0001180)2.67816903
29Pancreatic cysts (HP:0001737)2.65341400
30Abnormal mitochondria in muscle tissue (HP:0008316)2.58583862
31Nephrogenic diabetes insipidus (HP:0009806)2.54584221
32Myelomeningocele (HP:0002475)2.52479006
33Volvulus (HP:0002580)2.49792544
34Abnormality of the lacrimal duct (HP:0011481)2.43266329
35Nasolacrimal duct obstruction (HP:0000579)2.43178898
36Acute encephalopathy (HP:0006846)2.41588971
37White forelock (HP:0002211)2.41311286
38Abnormality of the pulmonary veins (HP:0011718)2.40938084
39Sex reversal (HP:0012245)2.40512004
40Abnormal sex determination (HP:0012244)2.40512004
41Intellectual disability, moderate (HP:0002342)2.40327709
42Leukodystrophy (HP:0002415)2.38861872
43Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.37041595
44Cortical dysplasia (HP:0002539)2.36756915
45Gastrointestinal atresia (HP:0002589)2.36260796
46Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.35412763
47Optic disc pallor (HP:0000543)2.35283741
48Abnormality of the nasolacrimal system (HP:0000614)2.34894496
49Hypoplastic heart (HP:0001961)2.32878334
50Esophageal atresia (HP:0002032)2.32295279
51Termporal pattern (HP:0011008)2.30186881
52Insidious onset (HP:0003587)2.30186881
53Oligodactyly (HP:0012165)2.29038163
54Vaginal atresia (HP:0000148)2.28817988
55Pulmonary artery stenosis (HP:0004415)2.27265799
56Patchy hypopigmentation of hair (HP:0011365)2.26788816
57Poor coordination (HP:0002370)2.26705898
58Renal Fanconi syndrome (HP:0001994)2.26002249
59Abnormality of the renal medulla (HP:0100957)2.25111020
60Optic nerve hypoplasia (HP:0000609)2.24442616
61Hypophosphatemic rickets (HP:0004912)2.24265841
62Genital tract atresia (HP:0001827)2.22767947
63Duplication of thumb phalanx (HP:0009942)2.22001667
64Renal hypoplasia (HP:0000089)2.19979675
65Cupped ear (HP:0000378)2.19005171
66Postaxial hand polydactyly (HP:0001162)2.18139061
67Recurrent corneal erosions (HP:0000495)2.18133415
68Neurofibrillary tangles (HP:0002185)2.16090678
69Cutaneous finger syndactyly (HP:0010554)2.15091568
70Anencephaly (HP:0002323)2.14833680
71Bifid tongue (HP:0010297)2.14663086
72Postaxial foot polydactyly (HP:0001830)2.13158531
73Vitreoretinal degeneration (HP:0000655)2.13048918
74Spastic gait (HP:0002064)2.11742966
75Broad foot (HP:0001769)2.11570369
76Preaxial hand polydactyly (HP:0001177)2.09930538
77Diastasis recti (HP:0001540)2.09013095
78Mitochondrial inheritance (HP:0001427)2.08415297
79Peripheral hypomyelination (HP:0007182)2.08326826
80Focal motor seizures (HP:0011153)2.06764055
81Abnormal lung lobation (HP:0002101)2.06036443
82Cerebellar dysplasia (HP:0007033)1.99884666
83Muscle hypertrophy of the lower extremities (HP:0008968)1.99690577
84Aqueductal stenosis (HP:0002410)1.99252492
85Preaxial foot polydactyly (HP:0001841)1.99092710
86Medial flaring of the eyebrow (HP:0010747)1.97511848
87Bilateral microphthalmos (HP:0007633)1.97001710
88Humeroradial synostosis (HP:0003041)1.96074162
89Synostosis involving the elbow (HP:0003938)1.96074162
90Increased corneal curvature (HP:0100692)1.94933875
91Keratoconus (HP:0000563)1.94933875
92Aplasia/Hypoplasia of the tongue (HP:0010295)1.94710932
93Scanning speech (HP:0002168)1.94430395
94Triphalangeal thumb (HP:0001199)1.94174564
95Hypoplastic pelvis (HP:0008839)1.92962193
96Abnormal auditory evoked potentials (HP:0006958)1.91875528
97Double outlet right ventricle (HP:0001719)1.91145151
98Congenital malformation of the right heart (HP:0011723)1.91145151
99Ulnar claw (HP:0001178)1.90393623
100Aplasia/Hypoplasia of the sternum (HP:0006714)1.89892746
101Hyperglycinemia (HP:0002154)1.89502490
102Sclerocornea (HP:0000647)1.88602414
103Micropenis (HP:0000054)1.88428191
104Hemivertebrae (HP:0002937)1.86426673
105Labial hypoplasia (HP:0000066)1.86398620
106Cutaneous syndactyly (HP:0012725)1.85858019
107Conical tooth (HP:0000698)1.85347136
108Maternal diabetes (HP:0009800)1.83463943
109Duplicated collecting system (HP:0000081)1.83000678
110Gait imbalance (HP:0002141)1.82896300
111Abnormality of glycolysis (HP:0004366)1.82351247
112Increased serum pyruvate (HP:0003542)1.82351247
113Supernumerary spleens (HP:0009799)1.81642756
114Hepatoblastoma (HP:0002884)1.81493043
115Enlarged kidneys (HP:0000105)1.81410946
116Lissencephaly (HP:0001339)1.81180516
117Increased hepatocellular lipid droplets (HP:0006565)1.80907657
118Growth hormone deficiency (HP:0000824)1.80777313
119Midline defect of the nose (HP:0004122)1.79094301
120Renal dysplasia (HP:0000110)1.78894911
121Meckel diverticulum (HP:0002245)1.78479480
122Abnormality of the ileum (HP:0001549)1.78189837
123Absent/shortened dynein arms (HP:0200106)1.77701629
124Dynein arm defect of respiratory motile cilia (HP:0012255)1.77701629
125Specific learning disability (HP:0001328)1.77467217
126Overfolded helix (HP:0000396)1.77316543
127Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.76953154
128Short 4th metacarpal (HP:0010044)1.76953154
1293-Methylglutaconic aciduria (HP:0003535)1.76729911
130Concave nail (HP:0001598)1.76162310
131Congenital sensorineural hearing impairment (HP:0008527)1.75130328
132Calf muscle hypertrophy (HP:0008981)1.74920266
133Chorioretinal coloboma (HP:0000567)1.74853195
134Increased CSF lactate (HP:0002490)1.74783569
135Atonic seizures (HP:0010819)1.74520733
136Hypoplastic female external genitalia (HP:0012815)1.74366711
137Thickened helices (HP:0000391)1.73722387
138Atelectasis (HP:0100750)1.73161544
139Dandy-Walker malformation (HP:0001305)1.72981269
140Split foot (HP:0001839)1.72765525
141Abnormality of the phalanges of the 2nd finger (HP:0009541)1.71048011
142True hermaphroditism (HP:0010459)1.70984324
143Cystic liver disease (HP:0006706)1.70656071
144Hypoplasia of the iris (HP:0007676)1.70534873
145High anterior hairline (HP:0009890)1.69262271
146Aplasia/Hypoplasia of the tibia (HP:0005772)1.69155607
147Aplasia/Hypoplasia of the uvula (HP:0010293)1.69004940
148Urinary bladder sphincter dysfunction (HP:0002839)1.68916380
149Congenital primary aphakia (HP:0007707)1.68212965
150Drooling (HP:0002307)1.67943321
151Abnormality of the antihelix (HP:0009738)1.67770839
152Morphological abnormality of the middle ear (HP:0008609)1.67764479
153Hypoplasia of the ulna (HP:0003022)1.67624988
154Abnormality of the incisor (HP:0000676)1.67490246
155Occipital encephalocele (HP:0002085)1.66665320
156Decreased testicular size (HP:0008734)1.66646283
157Male pseudohermaphroditism (HP:0000037)1.66641503
158Mixed hearing impairment (HP:0000410)1.66389362
159Abnormality of the aortic arch (HP:0012303)1.65517725
160Polydipsia (HP:0001959)1.65244288
161Abnormal drinking behavior (HP:0030082)1.65244288
162Holoprosencephaly (HP:0001360)1.65047521
163Coronal craniosynostosis (HP:0004440)1.64963390
164Anophthalmia (HP:0000528)1.64754789
165Partial agenesis of the corpus callosum (HP:0001338)1.64658125
166Bell-shaped thorax (HP:0001591)1.64571450
167Onion bulb formation (HP:0003383)1.64231042
168Rib fusion (HP:0000902)1.63864672
169Ectopic kidney (HP:0000086)1.63393035
170Abnormality of the middle phalanges of the toes (HP:0010183)1.63222559
171Absent radius (HP:0003974)1.62338260
172Aplasia involving forearm bones (HP:0009822)1.61878655
173Absent forearm bone (HP:0003953)1.61878655
174Narrow forehead (HP:0000341)1.60478401
175Aganglionic megacolon (HP:0002251)1.57189773
176Short tibia (HP:0005736)1.56808709

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK394.12704407
2CASK4.11347099
3PRPF4B3.45204452
4WNK33.40334307
5TNIK2.93983009
6OXSR12.64701263
7BCR2.55563021
8MAP3K42.46946759
9TNK22.41329672
10TRIM282.31428146
11OBSCN2.18207487
12PKN12.17377835
13WEE12.13790962
14MKNK12.00271635
15WNK41.95695180
16PLK41.90830616
17MKNK21.90370661
18LIMK11.87579568
19BUB11.79879582
20MAPK131.75775292
21NEK11.70572972
22NEK61.67924997
23CLK11.54115815
24UHMK11.52065382
25MUSK1.50442335
26IRAK21.50413573
27GRK71.49255424
28PBK1.47944646
29NEK21.47563572
30MAP4K21.47346587
31CDC71.41753582
32WNK11.41564227
33EPHB11.41557389
34DYRK21.41226560
35MARK11.40615756
36CSNK1A1L1.39961629
37PLK31.34682117
38FGFR21.34462076
39CSNK1G31.33502261
40BRSK21.30894539
41TTK1.29555488
42YES11.27381708
43PLK21.26462704
44CSNK1G11.24883223
45BMPR1B1.23691372
46CAMK2B1.20953081
47BLK1.16786178
48DYRK31.15324797
49FRK1.14387267
50PINK11.08467874
51PLK11.07788060
52PRKCG1.07260519
53IRAK11.06405253
54STK38L1.05573622
55SGK4941.05121101
56SGK2231.05121101
57PNCK1.03147061
58ZAK1.02773994
59STK161.02670704
60SRPK11.01741602
61CAMK2D1.01074493
62FGFR10.94188015
63TAF10.93447454
64MAP3K120.91762045
65ADRBK20.90446186
66MAP2K70.90260689
67CSNK1G20.89698520
68CDK190.89238264
69CAMK2A0.88804499
70ACVR1B0.87121186
71FLT30.86977117
72EPHA40.85581871
73DMPK0.84501685
74ROCK20.83272890
75EPHB20.81708949
76PIK3CA0.80783698
77INSRR0.80475439
78PKN20.77763395
79TGFBR10.77617034
80MYLK0.77473880
81CDK30.76699778
82NUAK10.76669899
83STK110.75881059
84BMX0.75492358
85GRK10.74228554
86BMPR20.73961244
87BRD40.73826487
88LATS20.73288066
89LATS10.70701000
90FGR0.69144634
91ERBB20.68423518
92MAPKAPK50.68125984
93STK30.67964788
94KSR10.66180392
95PRKCE0.65813561
96ICK0.65451697
97NTRK30.64631373
98PHKG20.64511903
99PHKG10.64511903
100CAMK2G0.64511856
101MET0.64405210
102PASK0.63412511
103DYRK1A0.62749875
104IRAK40.62696759
105BRSK10.62460779
106ROCK10.61728353
107VRK10.61066843
108VRK20.60604373
109PAK30.59146421
110PRKG10.58971354
111MAPK150.58751145
112MAP2K40.58543485
113NTRK20.58273911
114NTRK10.57857398
115TLK10.56905517
116RPS6KA40.56089957
117PRKD20.54940043
118PRKCQ0.54707235
119CSNK1A10.54574838
120AURKB0.53765490
121CDK50.53335100
122PRKD10.53227564
123EIF2AK20.52982112
124CSNK1E0.52778682
125CHEK20.51988131
126RPS6KA50.51096388
127NME10.51082675
128PAK60.49456096
129TIE10.48845968
130TYRO30.48190677
131ERBB30.46322100
132TRPM70.46138723
133ATR0.45295229
134PRKACA0.45105838
135MAP3K90.44715884
136CAMK1G0.43420419
137PRKACB0.42505813
138ATM0.41472466
139TSSK60.40540713
140FES0.40378182
141CSNK1D0.40143037
142FYN0.39458739
143IRAK30.37913041
144CCNB10.37634318
145MINK10.36532335
146NLK0.36350993
147ADRBK10.36318500
148ABL20.35461303
149EPHA30.35237065
150SGK20.33583990

Predicted pathways (KEGG)

RankGene SetZ-score
1Terpenoid backbone biosynthesis_Homo sapiens_hsa009004.66993537
2Steroid biosynthesis_Homo sapiens_hsa001003.45327950
3Fatty acid elongation_Homo sapiens_hsa000623.33627679
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.26357456
5Oxidative phosphorylation_Homo sapiens_hsa001903.23423008
6Axon guidance_Homo sapiens_hsa043602.75125119
7Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.70193309
8Protein export_Homo sapiens_hsa030602.54733308
9Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.51857638
10Ether lipid metabolism_Homo sapiens_hsa005652.48757407
11Parkinsons disease_Homo sapiens_hsa050122.46478234
12Alzheimers disease_Homo sapiens_hsa050102.10432520
13Cardiac muscle contraction_Homo sapiens_hsa042601.93028857
14Huntingtons disease_Homo sapiens_hsa050161.86124761
15Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.78628156
16Nicotine addiction_Homo sapiens_hsa050331.75545010
17Homologous recombination_Homo sapiens_hsa034401.69953361
18Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.62587662
19Mismatch repair_Homo sapiens_hsa034301.57216130
20Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.57114464
21Basal cell carcinoma_Homo sapiens_hsa052171.53232233
22Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.49250369
23Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.43182227
24Sphingolipid metabolism_Homo sapiens_hsa006001.40547236
25Non-homologous end-joining_Homo sapiens_hsa034501.38374338
26Sulfur metabolism_Homo sapiens_hsa009201.38361689
27Serotonergic synapse_Homo sapiens_hsa047261.37868197
28Ribosome_Homo sapiens_hsa030101.34115593
29Linoleic acid metabolism_Homo sapiens_hsa005911.29854214
30Cell cycle_Homo sapiens_hsa041101.24325851
31Arachidonic acid metabolism_Homo sapiens_hsa005901.23843099
32RNA degradation_Homo sapiens_hsa030181.23541825
33Steroid hormone biosynthesis_Homo sapiens_hsa001401.22499455
34Hedgehog signaling pathway_Homo sapiens_hsa043401.21579012
35RNA polymerase_Homo sapiens_hsa030201.18806652
36Histidine metabolism_Homo sapiens_hsa003401.16300301
37Butanoate metabolism_Homo sapiens_hsa006501.15892449
38Glutamatergic synapse_Homo sapiens_hsa047241.14176214
39RNA transport_Homo sapiens_hsa030131.14044120
40Cysteine and methionine metabolism_Homo sapiens_hsa002701.14024672
41Morphine addiction_Homo sapiens_hsa050321.13716630
42Long-term depression_Homo sapiens_hsa047301.12882141
43Taste transduction_Homo sapiens_hsa047421.11374294
44Phototransduction_Homo sapiens_hsa047441.10351255
45TGF-beta signaling pathway_Homo sapiens_hsa043501.09413231
46Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.05942764
47Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.05544166
48alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.05294501
49Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.04587791
50Autoimmune thyroid disease_Homo sapiens_hsa053201.04010991
51Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.02137977
52Oocyte meiosis_Homo sapiens_hsa041141.01966960
53Spliceosome_Homo sapiens_hsa030400.99630264
54Nitrogen metabolism_Homo sapiens_hsa009100.98335457
55Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.98179240
56Wnt signaling pathway_Homo sapiens_hsa043100.94371303
57Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.94369563
58Nucleotide excision repair_Homo sapiens_hsa034200.92245240
59Pyruvate metabolism_Homo sapiens_hsa006200.91065214
60One carbon pool by folate_Homo sapiens_hsa006700.90989018
61Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.90337572
62Propanoate metabolism_Homo sapiens_hsa006400.89813770
63mRNA surveillance pathway_Homo sapiens_hsa030150.88674350
64GABAergic synapse_Homo sapiens_hsa047270.85522251
65Selenocompound metabolism_Homo sapiens_hsa004500.85235062
66Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.82826549
67Dilated cardiomyopathy_Homo sapiens_hsa054140.82236994
68Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.81994406
69Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.79833243
70Arginine and proline metabolism_Homo sapiens_hsa003300.78464752
71Basal transcription factors_Homo sapiens_hsa030220.78388915
72Proteasome_Homo sapiens_hsa030500.75803007
73Renal cell carcinoma_Homo sapiens_hsa052110.75452764
74Ras signaling pathway_Homo sapiens_hsa040140.75231220
75DNA replication_Homo sapiens_hsa030300.73951669
76Vitamin B6 metabolism_Homo sapiens_hsa007500.73442708
77Tight junction_Homo sapiens_hsa045300.71870754
78Melanogenesis_Homo sapiens_hsa049160.70876304
79Peroxisome_Homo sapiens_hsa041460.70297611
80ErbB signaling pathway_Homo sapiens_hsa040120.69910235
81Adherens junction_Homo sapiens_hsa045200.69710284
82Circadian rhythm_Homo sapiens_hsa047100.69315073
83Ovarian steroidogenesis_Homo sapiens_hsa049130.68453735
84Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.68300506
85Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.67606107
86Base excision repair_Homo sapiens_hsa034100.66810699
87Insulin secretion_Homo sapiens_hsa049110.66499738
88Retinol metabolism_Homo sapiens_hsa008300.65424138
89Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.62994588
90Primary bile acid biosynthesis_Homo sapiens_hsa001200.62651627
91Olfactory transduction_Homo sapiens_hsa047400.61175628
92Cocaine addiction_Homo sapiens_hsa050300.60893694
93Maturity onset diabetes of the young_Homo sapiens_hsa049500.60446086
942-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.59994413
95Tyrosine metabolism_Homo sapiens_hsa003500.59449737
96Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.59443407
97Fanconi anemia pathway_Homo sapiens_hsa034600.57822860
98Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.56799204
99Metabolic pathways_Homo sapiens_hsa011000.55959384
100Vitamin digestion and absorption_Homo sapiens_hsa049770.54356332
101Purine metabolism_Homo sapiens_hsa002300.54263151
102Amphetamine addiction_Homo sapiens_hsa050310.53487338
103Tryptophan metabolism_Homo sapiens_hsa003800.53470815
104Prostate cancer_Homo sapiens_hsa052150.53253705
105Folate biosynthesis_Homo sapiens_hsa007900.52825851
106Hippo signaling pathway_Homo sapiens_hsa043900.51766061
107beta-Alanine metabolism_Homo sapiens_hsa004100.51312213
108Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.49983668
109Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.49879525
110Vascular smooth muscle contraction_Homo sapiens_hsa042700.49042600
111Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.48188530
112Cholinergic synapse_Homo sapiens_hsa047250.46360643
113Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.46035359
114Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.45929481
115Melanoma_Homo sapiens_hsa052180.45271503
116Fatty acid metabolism_Homo sapiens_hsa012120.45133460
117Circadian entrainment_Homo sapiens_hsa047130.43519395
118Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.43416176
119Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.42499558
120Chemical carcinogenesis_Homo sapiens_hsa052040.41783910
121Regulation of actin cytoskeleton_Homo sapiens_hsa048100.40840303
122Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.40478636
123Choline metabolism in cancer_Homo sapiens_hsa052310.39113119
124Calcium signaling pathway_Homo sapiens_hsa040200.38415456
125Sulfur relay system_Homo sapiens_hsa041220.38032204
126Asthma_Homo sapiens_hsa053100.36837946
127Glutathione metabolism_Homo sapiens_hsa004800.36009895
128Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.35723469
129MicroRNAs in cancer_Homo sapiens_hsa052060.35263818
130ECM-receptor interaction_Homo sapiens_hsa045120.33395048
131Gap junction_Homo sapiens_hsa045400.33222449
132Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.33068349
133PI3K-Akt signaling pathway_Homo sapiens_hsa041510.33016121
134Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.32215374
135Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.30893849
136Dopaminergic synapse_Homo sapiens_hsa047280.28855896
137Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.27086955
138Rheumatoid arthritis_Homo sapiens_hsa053230.27085656
139cAMP signaling pathway_Homo sapiens_hsa040240.26910777
140Lysine degradation_Homo sapiens_hsa003100.26798595
141Mineral absorption_Homo sapiens_hsa049780.26068604

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