FCHSD2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)4.78045839
2antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.00062885
3histone H3-K4 trimethylation (GO:0080182)3.97544889
4immunoglobulin mediated immune response (GO:0016064)3.81909273
5NIK/NF-kappaB signaling (GO:0038061)3.78197056
6positive regulation of cellular amide metabolic process (GO:0034250)3.75520018
7response to peptidoglycan (GO:0032494)3.73607128
8histone H3-K36 demethylation (GO:0070544)3.67641822
9modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.66481687
10positive regulation by organism of defense response of other organism involved in symbiotic interact3.66481687
11modulation by symbiont of host immune response (GO:0052553)3.66481687
12positive regulation by symbiont of host defense response (GO:0052509)3.66481687
13modulation by symbiont of host defense response (GO:0052031)3.66481687
14modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.66481687
15cellular extravasation (GO:0045123)3.65781782
16positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.63223799
17mature B cell differentiation (GO:0002335)3.61635195
18regulation of RIG-I signaling pathway (GO:0039535)3.57921851
19regulation of B cell receptor signaling pathway (GO:0050855)3.55283336
20positive thymic T cell selection (GO:0045059)3.52887947
21regulation of interferon-beta biosynthetic process (GO:0045357)3.52678066
22negative regulation of erythrocyte differentiation (GO:0045647)3.42013543
23B cell receptor signaling pathway (GO:0050853)3.39368382
24positive regulation of B cell differentiation (GO:0045579)3.32750535
25detection of molecule of bacterial origin (GO:0032490)3.30524793
26regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)3.28100663
27negative regulation of interleukin-12 production (GO:0032695)3.25121743
28detection of bacterium (GO:0016045)3.24135401
29positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.22442364
30B cell homeostasis (GO:0001782)3.22091468
31neutrophil activation involved in immune response (GO:0002283)3.20168898
32germinal center formation (GO:0002467)3.19280760
33regulation of interleukin-12 biosynthetic process (GO:0045075)3.17028292
34microglial cell activation (GO:0001774)3.16996422
35regulation of gamma-delta T cell activation (GO:0046643)3.15118812
36positive T cell selection (GO:0043368)3.12947237
37macrophage activation involved in immune response (GO:0002281)3.12038497
38I-kappaB phosphorylation (GO:0007252)3.10947132
39detection of external biotic stimulus (GO:0098581)3.10719236
40regulation of B cell differentiation (GO:0045577)3.10562789
41definitive hemopoiesis (GO:0060216)3.10309555
42T cell selection (GO:0045058)3.05641694
43response to host immune response (GO:0052572)3.05529785
44response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.05529785
45positive regulation of interferon-alpha production (GO:0032727)3.01767736
46regulation of mast cell degranulation (GO:0043304)3.01735953
47negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.00061908
48negative regulation of translation, ncRNA-mediated (GO:0040033)3.00061908
49regulation of translation, ncRNA-mediated (GO:0045974)3.00061908
50response to protozoan (GO:0001562)2.98715600
51positive regulation of mast cell activation (GO:0033005)2.95315402
52thymic T cell selection (GO:0045061)2.93403707
53regulation of germinal center formation (GO:0002634)2.88011805
54response to host (GO:0075136)2.87903993
55response to host defenses (GO:0052200)2.87903993
56response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.87903993
57regulation of interferon-alpha production (GO:0032647)2.86901757
58T-helper 1 type immune response (GO:0042088)2.86445286
59B cell mediated immunity (GO:0019724)2.85747198
60regulation of macrophage cytokine production (GO:0010935)2.84753382
61regulation of mast cell activation involved in immune response (GO:0033006)2.84384141
62response to muramyl dipeptide (GO:0032495)2.83015628
63antigen processing and presentation of endogenous antigen (GO:0019883)2.81783456
64B cell proliferation (GO:0042100)2.81509927
65negative regulation of lymphocyte mediated immunity (GO:0002707)2.80899495
66negative regulation of T cell mediated immunity (GO:0002710)2.79813682
67positive regulation of antigen processing and presentation (GO:0002579)2.79686828
68antigen receptor-mediated signaling pathway (GO:0050851)2.79638842
69positive regulation of mast cell degranulation (GO:0043306)2.79354307
70positive regulation of mast cell activation involved in immune response (GO:0033008)2.79354307
71regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.78835580
72regulation of myeloid leukocyte mediated immunity (GO:0002886)2.76832420
73macrophage activation (GO:0042116)2.76821170
74positive regulation of natural killer cell differentiation (GO:0032825)2.76543425
75G-protein coupled receptor internalization (GO:0002031)2.76277312
76regulation of T-helper 1 cell differentiation (GO:0045625)2.76059520
77positive regulation of type 2 immune response (GO:0002830)2.75863621
78positive regulation of macrophage cytokine production (GO:0060907)2.75307266
79peptidyl-lysine trimethylation (GO:0018023)2.73817025
80regulation of mast cell activation (GO:0033003)2.72513788
81regulation of T-helper 2 cell differentiation (GO:0045628)2.72274221
82regulation of leukocyte degranulation (GO:0043300)2.71592728
83response to type I interferon (GO:0034340)2.71372173
84negative regulation of granulocyte differentiation (GO:0030853)2.70563795
85cellular response to type I interferon (GO:0071357)2.70231647
86type I interferon signaling pathway (GO:0060337)2.70231647
87positive regulation of granulocyte differentiation (GO:0030854)2.68545281
88myeloid dendritic cell activation (GO:0001773)2.68426499
89regulation of gamma-delta T cell differentiation (GO:0045586)2.68378705
90positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.68093854
91positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.67079983
92positive regulation of Rap GTPase activity (GO:0032854)2.64878173
93T cell costimulation (GO:0031295)2.64739825
94detection of biotic stimulus (GO:0009595)2.64572788
95interferon-gamma-mediated signaling pathway (GO:0060333)2.63902689
96regulation of alpha-beta T cell proliferation (GO:0046640)2.63790905
97negative regulation of leukocyte mediated immunity (GO:0002704)2.62561015
98regulation of dendritic cell antigen processing and presentation (GO:0002604)2.62018836
99leukocyte aggregation (GO:0070486)2.61076751
100negative thymic T cell selection (GO:0045060)2.60272278
101lymphocyte costimulation (GO:0031294)2.59999158
102regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.59641091
103lymph node development (GO:0048535)2.57985868
104positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.57148817
105regulation of platelet aggregation (GO:0090330)2.56869552
106positive regulation of interleukin-1 beta secretion (GO:0050718)2.55590896
107histamine secretion (GO:0001821)2.55514354
108B cell differentiation (GO:0030183)2.52350683
109superoxide anion generation (GO:0042554)2.51884092
110histone H3-K4 methylation (GO:0051568)2.51415512
111lymphoid progenitor cell differentiation (GO:0002320)2.51093783
112negative regulation of cell killing (GO:0031342)2.51019432
113negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.51019432
114response to interleukin-15 (GO:0070672)2.50464828
115negative T cell selection (GO:0043383)2.49905062
116mature B cell differentiation involved in immune response (GO:0002313)2.49671838
117cellular response to interleukin-15 (GO:0071350)2.49362718
118lymphocyte homeostasis (GO:0002260)2.49112099
119regulation of interleukin-1 beta secretion (GO:0050706)2.45851515
120neutrophil activation (GO:0042119)2.44969367
121regulation of B cell proliferation (GO:0030888)2.44418917
122positive regulation of interferon-beta production (GO:0032728)2.43885285
123G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.43844499
124positive regulation of interleukin-1 secretion (GO:0050716)2.43386467
125positive regulation of B cell proliferation (GO:0030890)2.42676242
126dendritic cell migration (GO:0036336)2.42146264
127neural tube formation (GO:0001841)2.41961175
128positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.41732602
129cellular response to exogenous dsRNA (GO:0071360)2.39903885
130antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.39338147
131antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.39338147
132dendritic cell chemotaxis (GO:0002407)2.37707446
133negative regulation of B cell proliferation (GO:0030889)2.37232458
134regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.36487266
135positive regulation of interleukin-12 production (GO:0032735)2.36327014
136T cell homeostasis (GO:0043029)2.36207527
137megakaryocyte development (GO:0035855)2.35895306
138defense response to protozoan (GO:0042832)2.35318666
139detection of other organism (GO:0098543)2.34686673
140positive regulation of humoral immune response (GO:0002922)2.30817191
141B cell activation (GO:0042113)2.29958403
142T cell migration (GO:0072678)2.29443171
143positive regulation of B cell activation (GO:0050871)2.28427395
144regulation of antigen processing and presentation (GO:0002577)2.25918255
145myeloid cell activation involved in immune response (GO:0002275)2.25241145
146myeloid dendritic cell differentiation (GO:0043011)2.25238758

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.65507714
2IRF8_22096565_ChIP-ChIP_GC-B_Human3.49764303
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.08116658
4SMAD_19615063_ChIP-ChIP_OVARY_Human3.06476546
5GBX2_23144817_ChIP-Seq_PC3_Human2.73757256
6MYB_21317192_ChIP-Seq_ERMYB_Mouse2.67265123
7MYC_22102868_ChIP-Seq_BL_Human2.67166270
8IRF8_21731497_ChIP-ChIP_J774_Mouse2.62256936
9IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.61638849
10NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.58856697
11BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.42078045
12IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.34094254
13VDR_24763502_ChIP-Seq_THP-1_Human2.26190947
14* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.17242478
15VDR_21846776_ChIP-Seq_THP-1_Human2.16707459
16* MYB_26560356_Chip-Seq_TH2_Human2.16047437
17VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.13651233
18CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.12173238
19IRF8_27001747_Chip-Seq_BMDM_Mouse2.08560699
20SCL_19346495_ChIP-Seq_HPC-7_Human2.08040343
21KDM2B_26808549_Chip-Seq_SUP-B15_Human2.03027618
22RUNX_20019798_ChIP-Seq_JUKART_Human1.97080092
23* STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.96651597
24TCF7_22412390_ChIP-Seq_EML_Mouse1.87648314
25SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.87120080
26ZFP57_27257070_Chip-Seq_ESCs_Mouse1.82903467
27* MAF_26560356_Chip-Seq_TH1_Human1.81433165
28* MYB_26560356_Chip-Seq_TH1_Human1.80624656
29SPI1_23547873_ChIP-Seq_NB4_Human1.80308353
30SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.79202903
31IGF1R_20145208_ChIP-Seq_DFB_Human1.79174226
32PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.74627451
33FLI1_27457419_Chip-Seq_LIVER_Mouse1.74491307
34GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.73934273
35KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.71219972
36PCGF2_27294783_Chip-Seq_ESCs_Mouse1.69423043
37STAT4_19710469_ChIP-ChIP_TH1__Mouse1.68957632
38NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.67855144
39MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.66174277
40NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.64575624
41* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.63017835
42EZH2_22144423_ChIP-Seq_EOC_Human1.62880685
43POU3F2_20337985_ChIP-ChIP_501MEL_Human1.62069302
44* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.59864900
45GATA3_27048872_Chip-Seq_THYMUS_Human1.59695027
46* UTX_26944678_Chip-Seq_JUKART_Human1.59446079
47RUNX1_22412390_ChIP-Seq_EML_Mouse1.57515904
48Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.57297269
49* KDM2B_26808549_Chip-Seq_DND41_Human1.56819022
50SUZ12_27294783_Chip-Seq_NPCs_Mouse1.55679604
51BRD4_27068464_Chip-Seq_AML-cells_Mouse1.54956230
52P300_19829295_ChIP-Seq_ESCs_Human1.54120342
53TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.53527414
54POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.51901479
55TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.51901479
56RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.51897691
57PCGF2_27294783_Chip-Seq_NPCs_Mouse1.51719827
58GATA1_19941827_ChIP-Seq_MEL_Mouse1.49922827
59* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.46934416
60NANOG_18555785_Chip-Seq_ESCs_Mouse1.46867009
61AR_21572438_ChIP-Seq_LNCaP_Human1.46782884
62* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.46767937
63TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.46598385
64NFE2_27457419_Chip-Seq_LIVER_Mouse1.46520671
65CDX2_19796622_ChIP-Seq_MESCs_Mouse1.44101688
66SALL1_21062744_ChIP-ChIP_HESCs_Human1.41903253
67BP1_19119308_ChIP-ChIP_Hs578T_Human1.40073356
68GATA1_22025678_ChIP-Seq_K562_Human1.38445179
69SMAD4_21799915_ChIP-Seq_A2780_Human1.38093152
70EZH2_27294783_Chip-Seq_NPCs_Mouse1.36628376
71EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.35857380
72E2F1_18555785_Chip-Seq_ESCs_Mouse1.35676851
73SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.33244303
74THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.32643256
75TP63_19390658_ChIP-ChIP_HaCaT_Human1.32151240
76* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.30547667
77NOTCH1_21737748_ChIP-Seq_TLL_Human1.29340173
78* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.29233788
79* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.27039906
80P53_22387025_ChIP-Seq_ESCs_Mouse1.26825534
81VDR_24787735_ChIP-Seq_THP-1_Human1.26308726
82ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.25894463
83CMYC_18555785_Chip-Seq_ESCs_Mouse1.25078185
84SUZ12_18555785_Chip-Seq_ESCs_Mouse1.23931711
85ZNF217_24962896_ChIP-Seq_MCF-7_Human1.23711549
86TAF15_26573619_Chip-Seq_HEK293_Human1.23192106
87PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.22062267
88PIAS1_25552417_ChIP-Seq_VCAP_Human1.21856045
89PU_27001747_Chip-Seq_BMDM_Mouse1.21065507
90STAT3_23295773_ChIP-Seq_U87_Human1.20312187
91STAT3_18555785_Chip-Seq_ESCs_Mouse1.19509849
92GATA2_21666600_ChIP-Seq_HMVEC_Human1.18280161
93* KDM2B_26808549_Chip-Seq_JURKAT_Human1.18251579
94NMYC_18555785_Chip-Seq_ESCs_Mouse1.16592463
95JARID2_20064375_ChIP-Seq_MESCs_Mouse1.16343872
96MAF_26560356_Chip-Seq_TH2_Human1.15910409
97EGR1_19374776_ChIP-ChIP_THP-1_Human1.13684064
98IKZF1_21737484_ChIP-ChIP_HCT116_Human1.11274572
99DROSHA_22980978_ChIP-Seq_HELA_Human1.10852133
100EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.10464621
101CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10346355
102* TCF4_23295773_ChIP-Seq_U87_Human1.10126800
103SPI1_23127762_ChIP-Seq_K562_Human1.09904150
104GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08773899
105TP53_16413492_ChIP-PET_HCT116_Human1.08465891
106OCT4_18555785_Chip-Seq_ESCs_Mouse1.08313674
107CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.07942866
108PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.07705135
109* GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.07608665
110P300_18555785_Chip-Seq_ESCs_Mouse1.07276386
111LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.07179575
112RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.07130928
113ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.06953238
114SMAD3_21741376_ChIP-Seq_EPCs_Human1.06944684
115ARNT_22903824_ChIP-Seq_MCF-7_Human1.06306838
116CIITA_25753668_ChIP-Seq_RAJI_Human1.05850176
117PU1_27457419_Chip-Seq_LIVER_Mouse1.05824848
118EWS_26573619_Chip-Seq_HEK293_Human1.05822932
119SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.04502837
120TCF4_18268006_ChIP-ChIP_LS174T_Human1.04185021
121SOX2_18555785_Chip-Seq_ESCs_Mouse1.03358805
122SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.03286908
123AR_25329375_ChIP-Seq_VCAP_Human1.02566522
124OCT4_21477851_ChIP-Seq_ESCs_Mouse1.01610903
125RUNX1_27457419_Chip-Seq_LIVER_Mouse1.01601977
126GATA3_26560356_Chip-Seq_TH2_Human1.01393475
127SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.01337410
128GATA1_19941826_ChIP-Seq_K562_Human1.01224054
129FUS_26573619_Chip-Seq_HEK293_Human1.01190487
130P53_22127205_ChIP-Seq_FIBROBLAST_Human1.00849646
131MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.00108281
132AHR_22903824_ChIP-Seq_MCF-7_Human0.99382813
133ESRRB_18555785_Chip-Seq_ESCs_Mouse0.99294896
134TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.99129356
135SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.98767325
136LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.97138086
137CTCF_18555785_Chip-Seq_ESCs_Mouse0.95616222
138GATA2_22383799_ChIP-Seq_G1ME_Mouse0.95482041
139ZFX_18555785_Chip-Seq_ESCs_Mouse0.95336686
140* KDM2B_26808549_Chip-Seq_REH_Human0.93483850
141RUNX2_22187159_ChIP-Seq_PCA_Human0.91265660
142EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.90420619
143GATA1_19941827_ChIP-Seq_MEL86_Mouse0.90401194
144STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.87458331
145* DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.85594098
146GATA2_19941826_ChIP-Seq_K562_Human0.84346574
147ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.83944359
148* ELK3_25401928_ChIP-Seq_HUVEC_Human0.82458571
149CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.82442314
150GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.78759629
151PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.78395180
152PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.76509178
153GATA1_22383799_ChIP-Seq_G1ME_Mouse0.75823847
154SMRT_27268052_Chip-Seq_Bcells_Human0.73624202
155CTNNB1_20460455_ChIP-Seq_HCT116_Human0.71873370
156* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.70958265
157BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.70604683
158STAT6_21828071_ChIP-Seq_BEAS2B_Human0.68985002
159TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.68581931
160CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.67910746
161KDM2B_26808549_Chip-Seq_K562_Human0.67692062
162NFIB_24661679_ChIP-Seq_LUNG_Mouse0.67409388
163CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.66822608
164CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.66722567
165CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.66675165
166CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.66118403

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation5.47366825
2MP0001835_abnormal_antigen_presentation4.21161923
3MP0005387_immune_system_phenotype3.14586307
4MP0001790_abnormal_immune_system3.14586307
5MP0001800_abnormal_humoral_immune3.03388707
6MP0002396_abnormal_hematopoietic_system2.73509366
7MP0005671_abnormal_response_to2.68872226
8MP0000685_abnormal_immune_system2.59987039
9MP0002452_abnormal_antigen_presenting2.56233177
10MP0003787_abnormal_imprinting2.53501902
11MP0005174_abnormal_tail_pigmentation2.49308119
12MP0001188_hyperpigmentation2.46316432
13MP0003183_abnormal_peptide_metabolism2.38867927
14MP0004510_myositis2.36198499
15MP0002723_abnormal_immune_serum2.27195636
16MP0000015_abnormal_ear_pigmentation2.21925528
17MP0005000_abnormal_immune_tolerance2.11578003
18MP0002420_abnormal_adaptive_immunity2.10847455
19MP0001819_abnormal_immune_cell2.10684525
20MP0002419_abnormal_innate_immunity1.97525955
21MP0002148_abnormal_hypersensitivity_rea1.93576997
22MP0005464_abnormal_platelet_physiology1.93076779
23MP0003828_pulmonary_edema1.90619497
24MP0002398_abnormal_bone_marrow1.88623100
25MP0009785_altered_susceptibility_to1.88257664
26MP0003172_abnormal_lysosome_physiology1.85626630
27MP0005025_abnormal_response_to1.84001350
28MP0002166_altered_tumor_susceptibility1.80236797
29MP0001986_abnormal_taste_sensitivity1.78087562
30MP0000716_abnormal_immune_system1.75398563
31MP0003763_abnormal_thymus_physiology1.74335282
32MP0001533_abnormal_skeleton_physiology1.69792686
33MP0004808_abnormal_hematopoietic_stem1.66252678
34MP0005646_abnormal_pituitary_gland1.64875289
35MP0003303_peritoneal_inflammation1.60226445
36MP0001873_stomach_inflammation1.57687623
37MP0002095_abnormal_skin_pigmentation1.57586121
38MP0003690_abnormal_glial_cell1.55123853
39MP0002138_abnormal_hepatobiliary_system1.51572166
40MP0006292_abnormal_olfactory_placode1.49574713
41MP0000465_gastrointestinal_hemorrhage1.46618995
42MP0002006_tumorigenesis1.41305477
43MP0002009_preneoplasia1.41095146
44MP0000689_abnormal_spleen_morphology1.39551353
45MP0003191_abnormal_cellular_cholesterol1.35874960
46MP0003724_increased_susceptibility_to1.33692630
47MP0008260_abnormal_autophagy1.33434199
48MP0010155_abnormal_intestine_physiology1.32689346
49MP0004883_abnormal_blood_vessel1.32080776
50MP0005645_abnormal_hypothalamus_physiol1.30801480
51MP0002429_abnormal_blood_cell1.30105479
52MP0005310_abnormal_salivary_gland1.29831402
53MP0009764_decreased_sensitivity_to1.26868744
54MP0005257_abnormal_intraocular_pressure1.26404926
55MP0002163_abnormal_gland_morphology1.25844580
56MP0003075_altered_response_to1.25574925
57MP0006082_CNS_inflammation1.23193721
58MP0003950_abnormal_plasma_membrane1.22402737
59MP0005423_abnormal_somatic_nervous1.21553843
60MP0002722_abnormal_immune_system1.21364345
61MP0002405_respiratory_system_inflammati1.19911132
62MP0003868_abnormal_feces_composition1.19662223
63MP0005058_abnormal_lysosome_morphology1.19270775
64MP0005409_darkened_coat_color1.18189024
65MP0003045_fibrosis1.17882898
66MP0001502_abnormal_circadian_rhythm1.16878466
67MP0002277_abnormal_respiratory_mucosa1.16162827
68MP0002102_abnormal_ear_morphology1.14833121
69MP0002928_abnormal_bile_duct1.14733674
70MP0001958_emphysema1.12213449
71MP0001851_eye_inflammation1.11807185
72MP0003300_gastrointestinal_ulcer1.11658751
73MP0000858_altered_metastatic_potential1.10850917
74MP0009278_abnormal_bone_marrow1.10482033
75MP0001879_abnormal_lymphatic_vessel1.09994293
76MP0000703_abnormal_thymus_morphology1.08705499
77MP0003436_decreased_susceptibility_to1.05615941
78MP0001845_abnormal_inflammatory_respons1.04281125
79MP0005075_abnormal_melanosome_morpholog1.03897196
80MP0000566_synostosis1.03526939
81MP0000371_diluted_coat_color1.03085414
82MP0004947_skin_inflammation1.01382541
83MP0008004_abnormal_stomach_pH0.99909855
84MP0000604_amyloidosis0.98700300
85MP0005166_decreased_susceptibility_to0.98483560
86MP0005379_endocrine/exocrine_gland_phen0.96196862
87MP0003448_altered_tumor_morphology0.94144919
88MP0000249_abnormal_blood_vessel0.93430657
89MP0005397_hematopoietic_system_phenotyp0.91867421
90MP0001545_abnormal_hematopoietic_system0.91867421
91MP0003656_abnormal_erythrocyte_physiolo0.91343076
92MP0000767_abnormal_smooth_muscle0.90750079
93MP0003279_aneurysm0.90558454
94MP0000920_abnormal_myelination0.90534625
95MP0005164_abnormal_response_to0.89583061
96MP0001486_abnormal_startle_reflex0.85780549
97MP0003091_abnormal_cell_migration0.84308852
98MP0001853_heart_inflammation0.84160662
99MP0003943_abnormal_hepatobiliary_system0.81380270
100MP0005167_abnormal_blood-brain_barrier0.80610306
101MP0005390_skeleton_phenotype0.79412709
102MP0000490_abnormal_crypts_of0.79183263
103MP0002998_abnormal_bone_remodeling0.78692681
104MP0002254_reproductive_system_inflammat0.78135745
105MP0008874_decreased_physiological_sensi0.75217533
106MP0009763_increased_sensitivity_to0.73609954
107MP0000343_altered_response_to0.73595665
108MP0009115_abnormal_fat_cell0.73509718
109MP0005451_abnormal_body_composition0.71717790
110MP0000778_abnormal_nervous_system0.70767711
111MP0002075_abnormal_coat/hair_pigmentati0.69772823
112MP0002133_abnormal_respiratory_system0.69456160
113MP0005388_respiratory_system_phenotype0.69456160
114MP0003221_abnormal_cardiomyocyte_apopto0.68465985
115MP0008058_abnormal_DNA_repair0.68015972
116MP0008469_abnormal_protein_level0.67735756
117MP0001915_intracranial_hemorrhage0.65783076
118MP0001348_abnormal_lacrimal_gland0.63889766
119MP0003795_abnormal_bone_structure0.63354803
120MP0002557_abnormal_social/conspecific_i0.61793751
121MP0003329_amyloid_beta_deposits0.61467917
122MP0004130_abnormal_muscle_cell0.61389553
123MP0002132_abnormal_respiratory_system0.61133240
124MP0003941_abnormal_skin_development0.60014744
125MP0003866_abnormal_defecation0.58711174
126MP0002877_abnormal_melanocyte_morpholog0.55805368
127MP0004484_altered_response_of0.53430249
128MP0001663_abnormal_digestive_system0.53256429
129MP0001186_pigmentation_phenotype0.53202223
130MP0002876_abnormal_thyroid_physiology0.52575806
131MP0009697_abnormal_copulation0.52531552
132MP0004742_abnormal_vestibular_system0.51982445
133MP0005621_abnormal_cell_physiology0.51258373
134MP0009745_abnormal_behavioral_response0.49540681
135MP0009333_abnormal_splenocyte_physiolog0.49519478
136MP0000383_abnormal_hair_follicle0.48816537
137MP0008995_early_reproductive_senescence0.48298044
138MP0001119_abnormal_female_reproductive0.48128738
139MP0004134_abnormal_chest_morphology0.48082492
140MP0002933_joint_inflammation0.47405246

Predicted human phenotypes

RankGene SetZ-score
1Agammaglobulinemia (HP:0004432)4.58368308
2Abnormal delayed hypersensitivity skin test (HP:0002963)3.66955420
3Abnormality of the fingertips (HP:0001211)3.51741638
4Spontaneous hematomas (HP:0007420)3.39649109
5Recurrent cutaneous fungal infections (HP:0011370)3.38800226
6Chronic mucocutaneous candidiasis (HP:0002728)3.38800226
7Recurrent viral infections (HP:0004429)3.34019455
8Gastrointestinal infarctions (HP:0005244)3.25025439
9Recurrent bacterial skin infections (HP:0005406)3.22021930
10Recurrent abscess formation (HP:0002722)3.17862619
11Recurrent fungal infections (HP:0002841)3.17052555
12Colitis (HP:0002583)3.12105418
13Chromosomal breakage induced by crosslinking agents (HP:0003221)3.07883140
14Abnormality of macrophages (HP:0004311)3.05401480
15Chromsome breakage (HP:0040012)3.03725456
16Panhypogammaglobulinemia (HP:0003139)3.01398732
17Myositis (HP:0100614)3.00996216
18Volvulus (HP:0002580)2.96129391
19Prostate neoplasm (HP:0100787)2.93419597
20Chest pain (HP:0100749)2.86940649
21Gastrointestinal stroma tumor (HP:0100723)2.86936419
22Retrobulbar optic neuritis (HP:0100654)2.85289980
23Optic neuritis (HP:0100653)2.85289980
24Vasculitis (HP:0002633)2.82364933
25Autoimmune thrombocytopenia (HP:0001973)2.78731568
26Inflammation of the large intestine (HP:0002037)2.78414205
27Chronic diarrhea (HP:0002028)2.78394190
28Meningitis (HP:0001287)2.67993879
29Peritonitis (HP:0002586)2.66468672
30Recurrent skin infections (HP:0001581)2.66293613
31Spondylolisthesis (HP:0003302)2.61811836
32Papilledema (HP:0001085)2.61104324
33Increased IgE level (HP:0003212)2.60835620
34Chronic otitis media (HP:0000389)2.58408340
35Hemoptysis (HP:0002105)2.55292613
36Thyroiditis (HP:0100646)2.54973271
37Abnormality of the peritoneum (HP:0002585)2.54044848
38Restrictive lung disease (HP:0002091)2.51518302
39Recurrent sinusitis (HP:0011108)2.48589187
40Verrucae (HP:0200043)2.47070456
41Papilloma (HP:0012740)2.47070456
42Gastrointestinal inflammation (HP:0004386)2.46409851
43Mediastinal lymphadenopathy (HP:0100721)2.45777371
44Lymphopenia (HP:0001888)2.41869383
45T lymphocytopenia (HP:0005403)2.41169160
46Acute myeloid leukemia (HP:0004808)2.39275406
47Urticaria (HP:0001025)2.38999440
48Abnormality of T cell number (HP:0011839)2.36738795
49Cellulitis (HP:0100658)2.36058010
50Recurrent bronchitis (HP:0002837)2.35516566
51Absent frontal sinuses (HP:0002688)2.32782958
52Stomatitis (HP:0010280)2.32329745
53Orchitis (HP:0100796)2.32279471
54Pulmonary infiltrates (HP:0002113)2.30751061
55Febrile seizures (HP:0002373)2.30617049
56Abnormality of cells of the lymphoid lineage (HP:0012140)2.30331371
57Hypoplasia of the thymus (HP:0000778)2.29664481
58Chronic sinusitis (HP:0011109)2.25933270
59Eczematoid dermatitis (HP:0000976)2.25761404
60Gingival bleeding (HP:0000225)2.25668777
61Abnormality of the pleura (HP:0002103)2.22759028
62Pulmonary embolism (HP:0002204)2.22637748
63Abnormality of the prostate (HP:0008775)2.22179473
64Viral hepatitis (HP:0006562)2.20490896
65Granulocytopenia (HP:0001913)2.19484194
66Stomach cancer (HP:0012126)2.17314982
67Asymmetric septal hypertrophy (HP:0001670)2.16835629
68Clubbing of toes (HP:0100760)2.16204650
69Prolonged bleeding time (HP:0003010)2.16182958
70Abnormality of the nasal septum (HP:0000419)2.14730565
71Sepsis (HP:0100806)2.14081839
72Alveolar cell carcinoma (HP:0006519)2.12178102
73Encephalitis (HP:0002383)2.10228098
74IgM deficiency (HP:0002850)2.09363681
75Abnormality of the intervertebral disk (HP:0005108)2.09285488
76Lip pit (HP:0100267)2.09137984
77Arterial tortuosity (HP:0005116)2.08127766
78Recurrent pneumonia (HP:0006532)2.08018585
79Fatigue (HP:0012378)2.07340134
80Protruding tongue (HP:0010808)2.06427957
81Neoplasm of the tracheobronchial system (HP:0100552)2.05754514
82Keratoconjunctivitis sicca (HP:0001097)2.05573479
83Abnormality of T cells (HP:0002843)2.05104675
84Arterial thrombosis (HP:0004420)2.03351397
85Abnormal hair whorl (HP:0010721)2.01968851
86Abnormality of the left ventricular outflow tract (HP:0011103)1.99794294
87Subaortic stenosis (HP:0001682)1.99794294
88Elevated erythrocyte sedimentation rate (HP:0003565)1.97114825
89Long eyelashes (HP:0000527)1.96729502
90Acute lymphatic leukemia (HP:0006721)1.96449606
91Generalized hypopigmentation of hair (HP:0011358)1.96312765
92Hypergammaglobulinemia (HP:0010702)1.96110300
93Abnormality of the columella (HP:0009929)1.95844503
94Systemic lupus erythematosus (HP:0002725)1.95332821
95Hematochezia (HP:0002573)1.93157815
96Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.92430209
97Recurrent lower respiratory tract infections (HP:0002783)1.92348984
98Vascular tortuosity (HP:0004948)1.90866263
99Inappropriate behavior (HP:0000719)1.90408307
100Acrocyanosis (HP:0001063)1.89961410
101IgA deficiency (HP:0002720)1.88859990
102Osteomyelitis (HP:0002754)1.88627510
103Fair hair (HP:0002286)1.88178691
104Pustule (HP:0200039)1.87975313
105Abnormality of T cell physiology (HP:0011840)1.87121819
106Glomerulopathy (HP:0100820)1.86368325
107Skin ulcer (HP:0200042)1.85153320
108IgG deficiency (HP:0004315)1.82395820
109Keratoconjunctivitis (HP:0001096)1.81949820
110Autoimmune hemolytic anemia (HP:0001890)1.79614531
111Amyloidosis (HP:0011034)1.78860643
112Syringomyelia (HP:0003396)1.77981635
113Spinal cord lesions (HP:0100561)1.77981635
114Periodontitis (HP:0000704)1.76925038
115Eosinophilia (HP:0001880)1.76617006
116Papillary thyroid carcinoma (HP:0002895)1.75576694
117Dysostosis multiplex (HP:0000943)1.74514854
118Arthralgia (HP:0002829)1.74073844
119Abnormality of binocular vision (HP:0011514)1.73988592
120Diplopia (HP:0000651)1.73988592
121Abnormality of the periventricular white matter (HP:0002518)1.73156360
122Skin rash (HP:0000988)1.72604165
123Abnormality of eosinophils (HP:0001879)1.72551929
124Ectopic kidney (HP:0000086)1.72357734
125Obstructive lung disease (HP:0006536)1.72276337
126Chronic obstructive pulmonary disease (HP:0006510)1.72276337
127Xerostomia (HP:0000217)1.71061356
128Leukocytosis (HP:0001974)1.70129726
129Thick eyebrow (HP:0000574)1.68824285
130Absent speech (HP:0001344)1.66818762
131Widely spaced teeth (HP:0000687)1.65946304
132Excessive salivation (HP:0003781)1.65020853
133Drooling (HP:0002307)1.65020853
134Increased IgM level (HP:0003496)1.63856531
135Gingivitis (HP:0000230)1.63663269
136Disinhibition (HP:0000734)1.63085596
137Epistaxis (HP:0000421)1.61895840
138Leukopenia (HP:0001882)1.60147069
139Mutism (HP:0002300)1.59352741
140Progressive inability to walk (HP:0002505)1.59100644
141Abnormality of salivation (HP:0100755)1.58193873
142Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.58058210
143Emphysema (HP:0002097)1.54458293
144Abnormality of the endocardium (HP:0004306)1.54434801
145Recurrent gram-negative bacterial infections (HP:0005420)1.54338312
146Midline defect of the nose (HP:0004122)1.53802781
147Abnormality of B cell number (HP:0010975)1.53749652
148B lymphocytopenia (HP:0010976)1.53749652

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K142.95128771
2MAP4K12.42682442
3JAK32.38792493
4IRAK42.36729674
5MAP3K132.36579209
6KIT2.29887277
7ERN12.21000598
8TYK22.18990870
9TNIK2.08804908
10BMPR22.08639938
11TGFBR22.06137521
12IKBKE2.03030950
13CSF1R1.97125728
14TXK1.96576633
15JAK11.94949679
16CASK1.94381320
17SIK21.81465936
18RIPK41.75376539
19SIK31.71690613
20IKBKB1.63371137
21MAP2K31.58949452
22CHUK1.58088556
23TAOK31.55256951
24FES1.49742693
25IRAK31.49551326
26SYK1.48468601
27MARK11.47101175
28TEC1.44330429
29TBK11.43905659
30MAPK131.43333711
31CAMK1D1.39165695
32CAMK1G1.37470790
33BTK1.37417133
34SGK21.30577742
35NUAK11.28126338
36EIF2AK21.26647492
37BLK1.26217515
38JAK21.26090622
39YES11.22095896
40FGFR31.20164193
41GRK11.16709891
42INSRR1.14048928
43HCK1.11527767
44CDK121.08109681
45ADRBK21.08073281
46PIK3CG1.02021383
47SGK30.99525517
48BRD40.99216447
49CDK90.98294509
50MAP3K60.97861568
51RIPK10.97015025
52PIK3CA0.96567156
53LYN0.96491555
54MAPK150.92959509
55MAP2K70.92084580
56LCK0.90261414
57KSR20.90105113
58EPHB10.89181838
59DMPK0.88813133
60CDK30.87835269
61ITK0.86925280
62PRPF4B0.85511851
63NTRK20.84918218
64ERBB30.84490144
65BMPR1B0.84051549
66IRAK10.82813272
67MAP3K100.81631408
68CDK60.80567804
69GRK60.80505097
70MKNK20.79477742
71PRKAA20.78856549
72MAPK70.77299333
73CAMKK10.76724120
74EPHA30.76561328
75CSK0.74700888
76CDK40.73926068
77TRIB30.73776923
78MAPK110.71767346
79PKN10.71497509
80LATS10.70941889
81NLK0.68827190
82IRAK20.68536187
83MATK0.66985279
84MAP3K10.66674160
85STK240.65023182
86PDPK10.63520676
87CLK10.63410525
88GRK70.62105434
89CAMKK20.61719320
90MARK30.61083122
91PDGFRB0.59357537
92RET0.58767574
93NTRK30.57932929
94MOS0.57574537
95NEK60.56933320
96SGK10.56817380
97FYN0.56512558
98CDK190.54822949
99MAPK40.54125350
100MARK20.53602025
101WNK10.53362440
102CAMK40.53295933
103TIE10.52469699
104STK30.52446608
105ZAP700.52331375
106HIPK20.51597131
107TAOK10.51090670
108MAP3K110.49675213
109SGK2230.48131627
110SGK4940.48131627
111PRKCQ0.48084464
112STK100.48067727
113MAP3K50.48022194
114ZAK0.47248135
115CCNB10.46853818
116PRKD20.46084140
117SIK10.45807698
118MAPK120.45739241
119TNK20.45616665
120ABL10.45581536
121PTK2B0.44975198
122DDR20.44758278
123MAP3K70.44720765
124IGF1R0.44607702
125CSNK1A1L0.42678436
126FGR0.42006673
127MUSK0.41672590
128TRPM70.39065511
129MELK0.38831571
130ATR0.38151370
131FGFR40.37978062
132CDC42BPA0.37056579
133MAPKAPK50.36931974
134NEK90.36603384
135RPS6KC10.35639170
136RPS6KL10.35639170
137AKT10.35603042
138PRKCH0.33837151
139PDK10.32842721

Predicted pathways (KEGG)

RankGene SetZ-score
1B cell receptor signaling pathway_Homo sapiens_hsa046622.43970396
2Primary immunodeficiency_Homo sapiens_hsa053402.37727580
3NF-kappa B signaling pathway_Homo sapiens_hsa040642.35909254
4Type I diabetes mellitus_Homo sapiens_hsa049402.11737835
5Intestinal immune network for IgA production_Homo sapiens_hsa046722.00795545
6Osteoclast differentiation_Homo sapiens_hsa043801.92570107
7Toll-like receptor signaling pathway_Homo sapiens_hsa046201.90138373
8Measles_Homo sapiens_hsa051621.87064847
9RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.85739490
10Leishmaniasis_Homo sapiens_hsa051401.71382157
11Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.68761666
12NOD-like receptor signaling pathway_Homo sapiens_hsa046211.64352572
13Allograft rejection_Homo sapiens_hsa053301.53639961
14Hematopoietic cell lineage_Homo sapiens_hsa046401.51989257
15TNF signaling pathway_Homo sapiens_hsa046681.50054743
16Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.45186952
17Influenza A_Homo sapiens_hsa051641.43029569
18Herpes simplex infection_Homo sapiens_hsa051681.39129459
19Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.38729382
20Jak-STAT signaling pathway_Homo sapiens_hsa046301.35871791
21Chemokine signaling pathway_Homo sapiens_hsa040621.34310652
22T cell receptor signaling pathway_Homo sapiens_hsa046601.29257297
23Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.27838551
24Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.25579277
25Transcriptional misregulation in cancer_Homo sapiens_hsa052021.19798951
26Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.19393590
27Hepatitis B_Homo sapiens_hsa051611.17996718
28Toxoplasmosis_Homo sapiens_hsa051451.17570975
29Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.14288532
30African trypanosomiasis_Homo sapiens_hsa051431.12707086
31Pancreatic cancer_Homo sapiens_hsa052121.12413537
32Rheumatoid arthritis_Homo sapiens_hsa053231.09355557
33Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.09324741
34Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.07773310
35Glycosaminoglycan degradation_Homo sapiens_hsa005311.05793656
36Tuberculosis_Homo sapiens_hsa051521.04771200
37Platelet activation_Homo sapiens_hsa046111.02372716
38Prolactin signaling pathway_Homo sapiens_hsa049171.00606984
39Phagosome_Homo sapiens_hsa041450.99354790
40Hepatitis C_Homo sapiens_hsa051600.99086268
41Phosphatidylinositol signaling system_Homo sapiens_hsa040700.96277305
42AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.93729487
43Autoimmune thyroid disease_Homo sapiens_hsa053200.93102208
44Nicotine addiction_Homo sapiens_hsa050330.92236651
45Renal cell carcinoma_Homo sapiens_hsa052110.90826747
46Chronic myeloid leukemia_Homo sapiens_hsa052200.90461848
47Non-homologous end-joining_Homo sapiens_hsa034500.90325040
48Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.89822794
49VEGF signaling pathway_Homo sapiens_hsa043700.88850536
50Type II diabetes mellitus_Homo sapiens_hsa049300.85980240
51Acute myeloid leukemia_Homo sapiens_hsa052210.84674153
52Apoptosis_Homo sapiens_hsa042100.83900995
53Morphine addiction_Homo sapiens_hsa050320.83425818
54Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.82875062
55Malaria_Homo sapiens_hsa051440.82177119
56Lysine degradation_Homo sapiens_hsa003100.81723796
57Dorso-ventral axis formation_Homo sapiens_hsa043200.81346872
58Colorectal cancer_Homo sapiens_hsa052100.80938932
59Pertussis_Homo sapiens_hsa051330.80636011
60Legionellosis_Homo sapiens_hsa051340.80402785
61Graft-versus-host disease_Homo sapiens_hsa053320.79152676
62Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.77250773
63Viral myocarditis_Homo sapiens_hsa054160.75584429
64Neurotrophin signaling pathway_Homo sapiens_hsa047220.75374659
65Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.74683642
66Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.74067382
67ABC transporters_Homo sapiens_hsa020100.72442438
68ErbB signaling pathway_Homo sapiens_hsa040120.71899884
69MAPK signaling pathway_Homo sapiens_hsa040100.71646597
70Small cell lung cancer_Homo sapiens_hsa052220.71444258
71mTOR signaling pathway_Homo sapiens_hsa041500.71372484
72Glutamatergic synapse_Homo sapiens_hsa047240.70793531
73Notch signaling pathway_Homo sapiens_hsa043300.70032077
74MicroRNAs in cancer_Homo sapiens_hsa052060.69419600
75Non-small cell lung cancer_Homo sapiens_hsa052230.69415392
76Olfactory transduction_Homo sapiens_hsa047400.69096270
77Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.67946000
78Choline metabolism in cancer_Homo sapiens_hsa052310.67599830
79HTLV-I infection_Homo sapiens_hsa051660.67592865
80Long-term potentiation_Homo sapiens_hsa047200.67017598
81Inositol phosphate metabolism_Homo sapiens_hsa005620.66883093
82GnRH signaling pathway_Homo sapiens_hsa049120.66548034
83Endometrial cancer_Homo sapiens_hsa052130.66099782
84Staphylococcus aureus infection_Homo sapiens_hsa051500.65871922
85Thyroid hormone signaling pathway_Homo sapiens_hsa049190.65809726
86Axon guidance_Homo sapiens_hsa043600.65507425
87Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.64041558
88Cholinergic synapse_Homo sapiens_hsa047250.63875219
89Circadian rhythm_Homo sapiens_hsa047100.63810011
90FoxO signaling pathway_Homo sapiens_hsa040680.63535077
91Epstein-Barr virus infection_Homo sapiens_hsa051690.63484571
92Carbohydrate digestion and absorption_Homo sapiens_hsa049730.63090844
93Estrogen signaling pathway_Homo sapiens_hsa049150.61945092
94Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.61707705
95cAMP signaling pathway_Homo sapiens_hsa040240.61137419
96Fanconi anemia pathway_Homo sapiens_hsa034600.61090657
97Shigellosis_Homo sapiens_hsa051310.61049367
98Aldosterone synthesis and secretion_Homo sapiens_hsa049250.60442884
99Asthma_Homo sapiens_hsa053100.60314678
100Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.60207563
101Amoebiasis_Homo sapiens_hsa051460.59218607
102Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.59138712
103Taste transduction_Homo sapiens_hsa047420.58914283
104Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.58688207
105Endocytosis_Homo sapiens_hsa041440.58649647
106Other glycan degradation_Homo sapiens_hsa005110.57390354
107Antigen processing and presentation_Homo sapiens_hsa046120.57279384
108Renin secretion_Homo sapiens_hsa049240.56492930
109Sphingolipid signaling pathway_Homo sapiens_hsa040710.56314755
110Phospholipase D signaling pathway_Homo sapiens_hsa040720.56245511
111Circadian entrainment_Homo sapiens_hsa047130.54214887
112Leukocyte transendothelial migration_Homo sapiens_hsa046700.53976179
113Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.53815029
114Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.53458589
115Ras signaling pathway_Homo sapiens_hsa040140.52880600
116Prostate cancer_Homo sapiens_hsa052150.50911648
117Glioma_Homo sapiens_hsa052140.49907962
118Ovarian steroidogenesis_Homo sapiens_hsa049130.49416570
119Salmonella infection_Homo sapiens_hsa051320.49405462
120Viral carcinogenesis_Homo sapiens_hsa052030.48526342
121Adipocytokine signaling pathway_Homo sapiens_hsa049200.45945049
122Lysosome_Homo sapiens_hsa041420.45729847
123Insulin resistance_Homo sapiens_hsa049310.45118425
124Focal adhesion_Homo sapiens_hsa045100.44053338
125SNARE interactions in vesicular transport_Homo sapiens_hsa041300.43155720
126HIF-1 signaling pathway_Homo sapiens_hsa040660.41502027
127Oxytocin signaling pathway_Homo sapiens_hsa049210.41355302

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