FAM96B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.55336620
2ATP synthesis coupled proton transport (GO:0015986)5.27578630
3energy coupled proton transport, down electrochemical gradient (GO:0015985)5.27578630
4proteasome assembly (GO:0043248)5.21176109
5respiratory chain complex IV assembly (GO:0008535)4.67183927
6cytochrome complex assembly (GO:0017004)4.50301391
7negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.43905814
8ribosomal small subunit biogenesis (GO:0042274)4.39040207
9ribosomal small subunit assembly (GO:0000028)4.26660020
10DNA deamination (GO:0045006)4.23978808
11positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.19520851
12anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:04.12052937
13negative regulation of ubiquitin-protein transferase activity (GO:0051444)4.11261892
14negative regulation of ligase activity (GO:0051352)4.11261892
15chaperone-mediated protein transport (GO:0072321)4.10194038
16regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.10134228
17protein neddylation (GO:0045116)4.10002254
18hydrogen ion transmembrane transport (GO:1902600)4.08557352
19DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:004.03754878
20viral transcription (GO:0019083)4.02758139
21respiratory electron transport chain (GO:0022904)4.01165382
22ATP biosynthetic process (GO:0006754)3.99822482
23mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.97471438
24regulation of cellular amino acid metabolic process (GO:0006521)3.95629730
25protein deneddylation (GO:0000338)3.95370048
26signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.94433461
27intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.94433461
28purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.94023413
29purine nucleoside triphosphate biosynthetic process (GO:0009145)3.92764123
30electron transport chain (GO:0022900)3.92429494
31translational termination (GO:0006415)3.92306577
32signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.92046797
33signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.92046797
34signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.92046797
35RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.82617297
36tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.82617297
37antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.81137867
38signal transduction involved in DNA damage checkpoint (GO:0072422)3.80720877
39signal transduction involved in DNA integrity checkpoint (GO:0072401)3.80720877
40termination of RNA polymerase III transcription (GO:0006386)3.79272599
41transcription elongation from RNA polymerase III promoter (GO:0006385)3.79272599
427-methylguanosine mRNA capping (GO:0006370)3.78883466
43maturation of SSU-rRNA (GO:0030490)3.77375553
447-methylguanosine RNA capping (GO:0009452)3.76104804
45RNA capping (GO:0036260)3.76104804
46signal transduction involved in cell cycle checkpoint (GO:0072395)3.74680952
47cullin deneddylation (GO:0010388)3.73439399
48L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.72637604
49positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.70795183
50protein maturation by protein folding (GO:0022417)3.63469332
51antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.63195244
52proton transport (GO:0015992)3.61759561
53protein-cofactor linkage (GO:0018065)3.58133389
54positive regulation of ligase activity (GO:0051351)3.56984623
55hydrogen transport (GO:0006818)3.54420224
56translational elongation (GO:0006414)3.53459811
57oxidative phosphorylation (GO:0006119)3.53298841
58SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.51451736
59ribonucleoside triphosphate biosynthetic process (GO:0009201)3.50819453
60cotranslational protein targeting to membrane (GO:0006613)3.48273378
61ribosomal large subunit biogenesis (GO:0042273)3.46515869
62sequestering of actin monomers (GO:0042989)3.46286494
63metallo-sulfur cluster assembly (GO:0031163)3.45626157
64iron-sulfur cluster assembly (GO:0016226)3.45626157
65mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.43974744
66mitochondrial respiratory chain complex I assembly (GO:0032981)3.43974744
67NADH dehydrogenase complex assembly (GO:0010257)3.43974744
68protein targeting to ER (GO:0045047)3.42870469
69translation (GO:0006412)3.38435911
70translational initiation (GO:0006413)3.34959205
71protein complex biogenesis (GO:0070271)3.34711906
72protein targeting to mitochondrion (GO:0006626)3.33128644
73telomere maintenance via semi-conservative replication (GO:0032201)3.32138411
74guanosine-containing compound biosynthetic process (GO:1901070)3.31834447
75regulation of ubiquitin-protein transferase activity (GO:0051438)3.29592637
76establishment of protein localization to mitochondrion (GO:0072655)3.29462014
77transcription-coupled nucleotide-excision repair (GO:0006283)3.28744738
78establishment of protein localization to mitochondrial membrane (GO:0090151)3.27596698
79protein localization to endoplasmic reticulum (GO:0070972)3.27189775
80GTP biosynthetic process (GO:0006183)3.27038595
81DNA damage response, signal transduction by p53 class mediator (GO:0030330)3.25673524
82mitochondrial transport (GO:0006839)3.24964988
83establishment of protein localization to endoplasmic reticulum (GO:0072599)3.24926313
84DNA strand elongation involved in DNA replication (GO:0006271)3.22935099
85viral life cycle (GO:0019058)3.21870478
86inner mitochondrial membrane organization (GO:0007007)3.21571075
87positive regulation of cell cycle arrest (GO:0071158)3.21167304
88nucleoside triphosphate biosynthetic process (GO:0009142)3.21147469
89ATP hydrolysis coupled proton transport (GO:0015991)3.21068531
90energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.21068531
91regulation of ligase activity (GO:0051340)3.19810207
92mitotic metaphase plate congression (GO:0007080)3.17261868
93cellular protein complex disassembly (GO:0043624)3.16909119
94formation of translation preinitiation complex (GO:0001731)3.15303116
95nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.14647822
96deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.14428791
97heart contraction (GO:0060047)3.14317584
98heart process (GO:0003015)3.14317584
99exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.13115138
100mannosylation (GO:0097502)3.12709084
101mitochondrial respiratory chain complex assembly (GO:0033108)3.11873322
102GDP-mannose metabolic process (GO:0019673)3.09610775
103telomere maintenance via recombination (GO:0000722)3.09500077
104ribonucleoprotein complex biogenesis (GO:0022613)3.08142010
105regulation of mitochondrial translation (GO:0070129)3.07644061
106rRNA modification (GO:0000154)3.05097222
107pseudouridine synthesis (GO:0001522)3.04926644
108DNA strand elongation (GO:0022616)3.04649860
109platelet dense granule organization (GO:0060155)3.03886227
110spliceosomal snRNP assembly (GO:0000387)3.01951203
111protein localization to mitochondrion (GO:0070585)3.00899533
112establishment of integrated proviral latency (GO:0075713)3.00524106
113base-excision repair, AP site formation (GO:0006285)2.97493731
114intracellular protein transmembrane import (GO:0044743)2.96668287
115negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.96578958
116kinetochore assembly (GO:0051382)2.95475029
117UTP metabolic process (GO:0046051)2.94547921
118cellular component biogenesis (GO:0044085)2.92931219
119nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.92001290
120pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.91825367
121G1/S transition of mitotic cell cycle (GO:0000082)2.90277950
122cell cycle G1/S phase transition (GO:0044843)2.90277950
123rRNA processing (GO:0006364)2.89594371
124UTP biosynthetic process (GO:0006228)2.89225935
125nucleotide-excision repair, DNA gap filling (GO:0006297)2.87725684
126DNA replication checkpoint (GO:0000076)2.87346473
127CENP-A containing nucleosome assembly (GO:0034080)2.87255839
128regulation of cellular amine metabolic process (GO:0033238)2.86941353
129amino acid salvage (GO:0043102)2.86140675
130L-methionine biosynthetic process (GO:0071265)2.86140675

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.44506188
2* GABP_17652178_ChIP-ChIP_JURKAT_Human4.11910990
3E2F7_22180533_ChIP-Seq_HELA_Human4.11029196
4EST1_17652178_ChIP-ChIP_JURKAT_Human4.01585168
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.97268708
6JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.93773364
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.66671807
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.56219920
9CREB1_15753290_ChIP-ChIP_HEK293T_Human3.51178328
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.42667117
11SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.27069929
12CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.00387251
13E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.99192746
14MYC_18358816_ChIP-ChIP_MESCs_Mouse2.97033941
15HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.86814297
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.84921885
17MYC_19030024_ChIP-ChIP_MESCs_Mouse2.72842957
18SRF_21415370_ChIP-Seq_HL-1_Mouse2.62132615
19* VDR_23849224_ChIP-Seq_CD4+_Human2.59709828
20FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.56427404
21MYC_19079543_ChIP-ChIP_MESCs_Mouse2.53461137
22DCP1A_22483619_ChIP-Seq_HELA_Human2.52471813
23E2F1_18555785_ChIP-Seq_MESCs_Mouse2.39989887
24XRN2_22483619_ChIP-Seq_HELA_Human2.38543964
25ELF1_17652178_ChIP-ChIP_JURKAT_Human2.37474067
26CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.31124476
27E2F4_17652178_ChIP-ChIP_JURKAT_Human2.26039067
28NELFA_20434984_ChIP-Seq_ESCs_Mouse2.22530266
29THAP11_20581084_ChIP-Seq_MESCs_Mouse2.14801105
30GABP_19822575_ChIP-Seq_HepG2_Human2.05866380
31YY1_21170310_ChIP-Seq_MESCs_Mouse2.02592645
32PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.00977387
33* FOXP3_21729870_ChIP-Seq_TREG_Human2.00123856
34ELK1_19687146_ChIP-ChIP_HELA_Human1.94324811
35* TTF2_22483619_ChIP-Seq_HELA_Human1.93264003
36BP1_19119308_ChIP-ChIP_Hs578T_Human1.90695700
37* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.87192961
38* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.85697787
39* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.82163634
40TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.81632963
41HOXB4_20404135_ChIP-ChIP_EML_Mouse1.76041843
42FOXM1_23109430_ChIP-Seq_U2OS_Human1.73443226
43MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.69234065
44NANOG_18555785_ChIP-Seq_MESCs_Mouse1.67389359
45* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.63495525
46CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.61330721
47POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.60753717
48CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.59701625
49ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.59272921
50MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.55901676
51PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.52499528
52MYCN_18555785_ChIP-Seq_MESCs_Mouse1.49249858
53ELK1_22589737_ChIP-Seq_MCF10A_Human1.46528256
54TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.41781064
55CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.37658120
56YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.34827474
57POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.34645650
58PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.34407835
59BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.33414022
60SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.32802133
61ZNF263_19887448_ChIP-Seq_K562_Human1.31724607
62ERG_20887958_ChIP-Seq_HPC-7_Mouse1.29033037
63FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.25563177
64IRF8_21731497_ChIP-ChIP_J774_Mouse1.25360796
65NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.25207758
66* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.23882000
67ZFX_18555785_ChIP-Seq_MESCs_Mouse1.23182158
68MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.23158540
69CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.16330649
70AR_21909140_ChIP-Seq_LNCAP_Human1.13397534
71SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.13247752
72NOTCH1_21737748_ChIP-Seq_TLL_Human1.12567579
73MYC_18940864_ChIP-ChIP_HL60_Human1.11612102
74CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.11588431
75ELF1_20517297_ChIP-Seq_JURKAT_Human1.09335900
76PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.08801247
77FOXP1_21924763_ChIP-Seq_HESCs_Human1.07912538
78STAT3_1855785_ChIP-Seq_MESCs_Mouse1.06903907
79TET1_21451524_ChIP-Seq_MESCs_Mouse1.06860886
80* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.06836201
81BCL6_27268052_Chip-Seq_Bcells_Human1.04136956
82E2F1_21310950_ChIP-Seq_MCF-7_Human1.02033412
83HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.01922885
84CIITA_25753668_ChIP-Seq_RAJI_Human1.01795489
85IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.01151118
86CTCF_26484167_Chip-Seq_Bcells_Mouse1.01089222
87SPI1_23547873_ChIP-Seq_NB4_Human1.00959685
88RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.00100951
89KDM5A_27292631_Chip-Seq_BREAST_Human0.99353598
90TBX5_21415370_ChIP-Seq_HL-1_Mouse0.97080322
91KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.96468630
92YY1_22570637_ChIP-Seq_MALME-3M_Human0.95066640
93TFEB_21752829_ChIP-Seq_HELA_Human0.95029530
94HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.94782547
95CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.94067209
96HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.92771020
97E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.92556619
98SOX2_18692474_ChIP-Seq_MEFs_Mouse0.91889991
99PADI4_21655091_ChIP-ChIP_MCF-7_Human0.91610864
100DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.91503476
101* CTCF_20526341_ChIP-Seq_ESCs_Human0.90910831
102SOX17_20123909_ChIP-Seq_XEN_Mouse0.89098985
103POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.88583303
104KLF4_18555785_ChIP-Seq_MESCs_Mouse0.88214468
105STAT4_19710469_ChIP-ChIP_TH1__Mouse0.88041505
106TP53_22573176_ChIP-Seq_HFKS_Human0.87455161
107* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.87029966
108OCT4_18692474_ChIP-Seq_MEFs_Mouse0.86620140
109EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.86213843
110IRF8_22096565_ChIP-ChIP_GC-B_Human0.86033318
111KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.85871517
112TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.85148211
113NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.85103439
114* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.82651669
115ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.82598475
116SRY_22984422_ChIP-ChIP_TESTIS_Rat0.82282580
117SOX2_18555785_ChIP-Seq_MESCs_Mouse0.81461198
118CTCF_18555785_ChIP-Seq_MESCs_Mouse0.80267751
119CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.80233301
120BCOR_27268052_Chip-Seq_Bcells_Human0.79777825
121ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.79739066
122* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.79687779
123GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.79089002
124PHF8_20622854_ChIP-Seq_HELA_Human0.78875993

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.02368479
2MP0003646_muscle_fatigue3.56113724
3MP0004957_abnormal_blastocyst_morpholog3.05064686
4MP0005451_abnormal_body_composition2.96090005
5MP0003077_abnormal_cell_cycle2.90990841
6MP0003718_maternal_effect2.66474101
7MP0003111_abnormal_nucleus_morphology2.54051489
8MP0004084_abnormal_cardiac_muscle2.52444588
9MP0003186_abnormal_redox_activity2.52069052
10MP0010094_abnormal_chromosome_stability2.51899010
11MP0008932_abnormal_embryonic_tissue2.51363608
12MP0003806_abnormal_nucleotide_metabolis2.42486753
13MP0008058_abnormal_DNA_repair2.34799418
14MP0000749_muscle_degeneration2.27303309
15MP0008007_abnormal_cellular_replicative2.12907127
16MP0001529_abnormal_vocalization2.01665882
17MP0008057_abnormal_DNA_replication1.94784588
18MP0006036_abnormal_mitochondrial_physio1.94704287
19MP0005379_endocrine/exocrine_gland_phen1.85173921
20MP0009333_abnormal_splenocyte_physiolog1.84700045
21MP0004142_abnormal_muscle_tone1.83329805
22MP0004036_abnormal_muscle_relaxation1.80353823
23MP0005084_abnormal_gallbladder_morpholo1.78930460
24MP0002736_abnormal_nociception_after1.77151349
25MP0009785_altered_susceptibility_to1.75120553
26MP0003221_abnormal_cardiomyocyte_apopto1.68650663
27MP0005330_cardiomyopathy1.68260506
28MP0002132_abnormal_respiratory_system1.68225933
29MP0008789_abnormal_olfactory_epithelium1.66268402
30MP0002148_abnormal_hypersensitivity_rea1.66110419
31MP0008875_abnormal_xenobiotic_pharmacok1.65179841
32MP0001984_abnormal_olfaction1.57369124
33MP0004510_myositis1.57299117
34MP0003011_delayed_dark_adaptation1.56423739
35MP0003315_abnormal_perineum_morphology1.54526831
36MP0005408_hypopigmentation1.54260961
37MP0006072_abnormal_retinal_apoptosis1.54169155
38MP0008995_early_reproductive_senescence1.49820938
39MP0009379_abnormal_foot_pigmentation1.49488950
40MP0001764_abnormal_homeostasis1.47774180
41MP0001835_abnormal_antigen_presentation1.47314293
42MP0009046_muscle_twitch1.44590953
43MP0003950_abnormal_plasma_membrane1.43923495
44MP0002102_abnormal_ear_morphology1.43129765
45MP0009840_abnormal_foam_cell1.41997392
46MP0002139_abnormal_hepatobiliary_system1.38908758
47MP0002972_abnormal_cardiac_muscle1.38351966
48MP0003123_paternal_imprinting1.38099190
49MP0001730_embryonic_growth_arrest1.34380955
50MP0005423_abnormal_somatic_nervous1.34340463
51MP0006035_abnormal_mitochondrial_morpho1.33786205
52MP0008775_abnormal_heart_ventricle1.33467469
53MP0002837_dystrophic_cardiac_calcinosis1.31915386
54MP0005671_abnormal_response_to1.31626529
55MP0003828_pulmonary_edema1.30811378
56MP0005332_abnormal_amino_acid1.30305537
57MP0000750_abnormal_muscle_regeneration1.30303042
58MP0005645_abnormal_hypothalamus_physiol1.29505589
59MP0004147_increased_porphyrin_level1.28333670
60MP0003786_premature_aging1.27998420
61MP0003567_abnormal_fetal_cardiomyocyte1.26793274
62MP0003195_calcinosis1.26446578
63MP0001968_abnormal_touch/_nociception1.26281621
64MP0003880_abnormal_central_pattern1.24161088
65MP0001905_abnormal_dopamine_level1.23427554
66MP0005058_abnormal_lysosome_morphology1.21920142
67MP0004215_abnormal_myocardial_fiber1.21117420
68MP0005394_taste/olfaction_phenotype1.18107929
69MP0005499_abnormal_olfactory_system1.18107929
70MP0000350_abnormal_cell_proliferation1.17234359
71MP0002106_abnormal_muscle_physiology1.16824770
72MP0003137_abnormal_impulse_conducting1.16168624
73MP0006276_abnormal_autonomic_nervous1.14199704
74MP0000343_altered_response_to1.14183144
75MP0001544_abnormal_cardiovascular_syste1.13360989
76MP0005385_cardiovascular_system_phenoty1.13360989
77MP0001853_heart_inflammation1.13028816
78MP0002822_catalepsy1.12986900
79MP0002876_abnormal_thyroid_physiology1.12781059
80MP0009745_abnormal_behavioral_response1.12100323
81MP0003136_yellow_coat_color1.11311177
82MP0008872_abnormal_physiological_respon1.11096993
83MP0008877_abnormal_DNA_methylation1.10326035
84MP0000490_abnormal_crypts_of1.10319123
85MP0002272_abnormal_nervous_system1.10153776
86MP0002938_white_spotting1.09624803
87MP0000313_abnormal_cell_death1.08732319
88MP0005636_abnormal_mineral_homeostasis1.08726950
89MP0002277_abnormal_respiratory_mucosa1.07919126
90MP0004145_abnormal_muscle_electrophysio1.07806838
91MP0002653_abnormal_ependyma_morphology1.06687645
92MP0005646_abnormal_pituitary_gland1.06284620
93MP0002127_abnormal_cardiovascular_syste1.06210085
94MP0006292_abnormal_olfactory_placode1.05276687
95MP0005000_abnormal_immune_tolerance1.04380695
96MP0001986_abnormal_taste_sensitivity1.03349846
97MP0002638_abnormal_pupillary_reflex1.02815021
98MP0001697_abnormal_embryo_size1.02000625
99MP0008260_abnormal_autophagy1.00784822
100MP0005670_abnormal_white_adipose1.00435104
101MP0005551_abnormal_eye_electrophysiolog0.99540237
102MP0000372_irregular_coat_pigmentation0.98827337
103MP0002693_abnormal_pancreas_physiology0.98593509
104MP0002332_abnormal_exercise_endurance0.98308996
105MP0003656_abnormal_erythrocyte_physiolo0.98202234
106MP0009764_decreased_sensitivity_to0.97270740
107MP0004087_abnormal_muscle_fiber0.96188066
108MP0005025_abnormal_response_to0.94907692
109MP0001919_abnormal_reproductive_system0.93208416
110MP0000358_abnormal_cell_content/0.92250105
111MP0002064_seizures0.91349407
112MP0005266_abnormal_metabolism0.89487106
113MP0005365_abnormal_bile_salt0.88812165
114MP0001756_abnormal_urination0.88145968
115MP0003436_decreased_susceptibility_to0.88043687
116MP0006138_congestive_heart_failure0.87984960
117MP0004133_heterotaxia0.87880687
118MP0005620_abnormal_muscle_contractility0.87537251
119MP0001970_abnormal_pain_threshold0.87122839
120MP0002210_abnormal_sex_determination0.86681816
121MP0009697_abnormal_copulation0.86053803
122MP0003763_abnormal_thymus_physiology0.85208399
123MP0002019_abnormal_tumor_incidence0.85099984
124MP0002163_abnormal_gland_morphology0.84622261
125MP0005389_reproductive_system_phenotype0.84353960
126MP0002452_abnormal_antigen_presenting0.83107735
127MP0002909_abnormal_adrenal_gland0.82862438
128MP0005369_muscle_phenotype0.82677102
129MP0002723_abnormal_immune_serum0.82464691
130MP0005253_abnormal_eye_physiology0.81988531
131MP0002398_abnormal_bone_marrow0.81530735
132MP0001119_abnormal_female_reproductive0.81510022
133MP0002405_respiratory_system_inflammati0.81042206
134MP0005584_abnormal_enzyme/coenzyme_acti0.80479207
135MP0002080_prenatal_lethality0.80459369
136MP0003075_altered_response_to0.80310481
137MP0000689_abnormal_spleen_morphology0.79973049
138MP0002229_neurodegeneration0.79841372
139MP0000858_altered_metastatic_potential0.79733638
140MP0002722_abnormal_immune_system0.78736141
141MP0005075_abnormal_melanosome_morpholog0.78189619
142MP0002429_abnormal_blood_cell0.78099454
143MP0000685_abnormal_immune_system0.77963550
144MP0001672_abnormal_embryogenesis/_devel0.77605347
145MP0005380_embryogenesis_phenotype0.77605347
146MP0001819_abnormal_immune_cell0.77071641
147MP0006082_CNS_inflammation0.76943966
148MP0002420_abnormal_adaptive_immunity0.76451987
149MP0003879_abnormal_hair_cell0.75494152
150MP0010630_abnormal_cardiac_muscle0.75230617
151MP0005410_abnormal_fertilization0.74535648
152MP0002090_abnormal_vision0.73873632
153MP0005319_abnormal_enzyme/_coenzyme0.72212352
154MP0005387_immune_system_phenotype0.71118106
155MP0001790_abnormal_immune_system0.71118106
156MP0009643_abnormal_urine_homeostasis0.71100981
157MP0002234_abnormal_pharynx_morphology0.71088780
158MP0002733_abnormal_thermal_nociception0.71014476
159MP0002160_abnormal_reproductive_system0.67040792
160MP0005386_behavior/neurological_phenoty0.66827052
161MP0004924_abnormal_behavior0.66827052
162MP0002557_abnormal_social/conspecific_i0.66719454
163MP0001873_stomach_inflammation0.66465010

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)5.40090339
2Mitochondrial inheritance (HP:0001427)4.96802779
3Abnormal mitochondria in muscle tissue (HP:0008316)4.85760734
4Hepatocellular necrosis (HP:0001404)4.34425084
5Increased CSF lactate (HP:0002490)4.33244381
6Acute encephalopathy (HP:0006846)4.30977239
7Increased hepatocellular lipid droplets (HP:0006565)4.27234288
8Decreased activity of mitochondrial respiratory chain (HP:0008972)4.19027273
9Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.19027273
10Progressive macrocephaly (HP:0004481)4.15228241
11Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)4.11708704
12Hepatic necrosis (HP:0002605)3.91916792
13Increased serum pyruvate (HP:0003542)3.91759844
14Abnormality of glycolysis (HP:0004366)3.91759844
153-Methylglutaconic aciduria (HP:0003535)3.88652741
16Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.80293578
17Lipid accumulation in hepatocytes (HP:0006561)3.78025927
18Abnormality of cells of the erythroid lineage (HP:0012130)3.72140758
19Exertional dyspnea (HP:0002875)3.61642276
20Abnormal number of erythroid precursors (HP:0012131)3.54421869
21Exercise intolerance (HP:0003546)3.48833674
22Increased serum lactate (HP:0002151)3.43661487
23Renal Fanconi syndrome (HP:0001994)3.32675314
24Cerebral hypomyelination (HP:0006808)3.28641273
25Respiratory failure (HP:0002878)3.20363766
26Reticulocytopenia (HP:0001896)3.13468843
27Increased intramyocellular lipid droplets (HP:0012240)3.13438102
28Lactic acidosis (HP:0003128)3.08729555
29Respiratory difficulties (HP:0002880)2.97315759
30Birth length less than 3rd percentile (HP:0003561)2.96570847
31Breast hypoplasia (HP:0003187)2.93751187
32Cerebral edema (HP:0002181)2.79048850
33Aplasia/Hypoplasia of the sacrum (HP:0008517)2.70260808
34Generalized aminoaciduria (HP:0002909)2.70070730
35Leukodystrophy (HP:0002415)2.68318461
36Lethargy (HP:0001254)2.67722012
37Increased muscle lipid content (HP:0009058)2.60407817
38Macrocytic anemia (HP:0001972)2.56228641
39Aplastic anemia (HP:0001915)2.54940625
40Abnormality of aromatic amino acid family metabolism (HP:0004338)2.53298294
41Carpal bone hypoplasia (HP:0001498)2.49022932
42Dicarboxylic aciduria (HP:0003215)2.44449846
43Abnormality of dicarboxylic acid metabolism (HP:0010995)2.44449846
44Oral leukoplakia (HP:0002745)2.44222955
45Optic disc pallor (HP:0000543)2.43039871
46Methylmalonic aciduria (HP:0012120)2.37058114
47Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.29852840
48Patellar aplasia (HP:0006443)2.27594498
49X-linked dominant inheritance (HP:0001423)2.27080042
50Rough bone trabeculation (HP:0100670)2.25849198
51Pallor (HP:0000980)2.24234108
52Lipoatrophy (HP:0100578)2.21158401
53Abnormality of the anterior horn cell (HP:0006802)2.17970514
54Degeneration of anterior horn cells (HP:0002398)2.17970514
55Aplasia/Hypoplasia of the patella (HP:0006498)2.17712554
56Abnormal protein glycosylation (HP:0012346)2.17206438
57Abnormal glycosylation (HP:0012345)2.17206438
58Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.17206438
59Abnormal protein N-linked glycosylation (HP:0012347)2.17206438
60Poor head control (HP:0002421)2.16534642
61Type I transferrin isoform profile (HP:0003642)2.16314372
62Amniotic constriction ring (HP:0009775)2.16046140
63Abnormality of placental membranes (HP:0011409)2.16046140
64Multiple enchondromatosis (HP:0005701)2.14369578
65Hyperphosphaturia (HP:0003109)2.10741154
66Progressive external ophthalmoplegia (HP:0000590)2.07134689
67Testicular atrophy (HP:0000029)2.06752251
68Methylmalonic acidemia (HP:0002912)2.05943671
69Hyperglycinemia (HP:0002154)2.03009520
70Nausea (HP:0002018)2.03002092
71Aplasia/Hypoplasia involving the musculature (HP:0001460)2.02719898
72Aplasia/hypoplasia of the uterus (HP:0008684)2.01964914
73Prolonged neonatal jaundice (HP:0006579)2.01906280
74Parakeratosis (HP:0001036)2.00972230
75CNS demyelination (HP:0007305)2.00647421
76Patent foramen ovale (HP:0001655)2.00187442
77Pancytopenia (HP:0001876)2.00138410
78Ventricular tachycardia (HP:0004756)1.99963409
79Adrenal hypoplasia (HP:0000835)1.99664604
80Neuroendocrine neoplasm (HP:0100634)1.98626798
81Progressive microcephaly (HP:0000253)1.98341382
82Sudden death (HP:0001699)1.97526169
83Hypokinesia (HP:0002375)1.96800602
84Hyperalaninemia (HP:0003348)1.96226001
85Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.96226001
86Abnormality of alanine metabolism (HP:0010916)1.96226001
87Microvesicular hepatic steatosis (HP:0001414)1.92997558
88Reduced antithrombin III activity (HP:0001976)1.92893666
89Myokymia (HP:0002411)1.92864894
90Secondary amenorrhea (HP:0000869)1.91418474
91Poor suck (HP:0002033)1.91340790
92Type 2 muscle fiber atrophy (HP:0003554)1.89144139
93Blindness (HP:0000618)1.88850354
94Premature graying of hair (HP:0002216)1.88494424
95Cleft eyelid (HP:0000625)1.88375263
96Abnormal trabecular bone morphology (HP:0100671)1.88182353
97Recurrent abscess formation (HP:0002722)1.87291817
98Molar tooth sign on MRI (HP:0002419)1.84589201
99Abnormality of midbrain morphology (HP:0002418)1.84589201
100Muscle fiber atrophy (HP:0100295)1.84279629
101Calf muscle hypertrophy (HP:0008981)1.83943706
102Muscle fiber splitting (HP:0003555)1.82879964
103Muscle hypertrophy of the lower extremities (HP:0008968)1.82242014
104Rhabdomyolysis (HP:0003201)1.81045337
105Abnormality of renal resorption (HP:0011038)1.79468739
106Vomiting (HP:0002013)1.78897803
107Microretrognathia (HP:0000308)1.78235366
108Emotional lability (HP:0000712)1.78071830
109Pancreatic cysts (HP:0001737)1.77313234
110Abnormality of the fetal cardiovascular system (HP:0010948)1.76754403
111Abnormal umbilical cord blood vessels (HP:0011403)1.76754403
112Single umbilical artery (HP:0001195)1.76754403
113Palpitations (HP:0001962)1.73498110
114Abnormality of urine glucose concentration (HP:0011016)1.73387104
115Glycosuria (HP:0003076)1.73387104
116Hypoplasia of the capital femoral epiphysis (HP:0003090)1.73359083
117Delusions (HP:0000746)1.73289270
118Opisthotonus (HP:0002179)1.73115049
119Gliosis (HP:0002171)1.72952218
120Premature ovarian failure (HP:0008209)1.72423341
121Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.72232850
122Ragged-red muscle fibers (HP:0003200)1.71438806
123Pulmonary artery stenosis (HP:0004415)1.69843733
124Polyphagia (HP:0002591)1.69754321
125Abnormality of the umbilical cord (HP:0010881)1.69689274
126Medial flaring of the eyebrow (HP:0010747)1.68857252
127Limb dystonia (HP:0002451)1.68242747
128Abnormal gallbladder physiology (HP:0012438)1.67536805
129Cholecystitis (HP:0001082)1.67536805
130Pheochromocytoma (HP:0002666)1.67481928
131Vacuolated lymphocytes (HP:0001922)1.66852075
132Increased IgM level (HP:0003496)1.64585557
133Mutism (HP:0002300)1.64412123
134Muscular hypotonia of the trunk (HP:0008936)1.64029995
135Delayed CNS myelination (HP:0002188)1.63854072
136Congenital ichthyosiform erythroderma (HP:0007431)1.62923914
137External ophthalmoplegia (HP:0000544)1.62151878
138Abnormality of the heme biosynthetic pathway (HP:0010472)1.61936511
139Dilated cardiomyopathy (HP:0001644)1.61548106
140CNS hypomyelination (HP:0003429)1.60897689
141Atrophy/Degeneration involving motor neurons (HP:0007373)1.55315392
142Unsteady gait (HP:0002317)1.55253291
143Abnormal urine phosphate concentration (HP:0012599)1.52318583
144Decreased electroretinogram (ERG) amplitude (HP:0000654)1.50935880
145Hypoplasia of the uterus (HP:0000013)1.49105890

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.25766292
2BUB14.02998410
3NME23.37407658
4EIF2AK13.18096208
5PBK2.81319855
6PLK42.72144114
7LIMK12.71148778
8WEE12.54786453
9OBSCN2.54019119
10ARAF2.49450977
11STK162.39281893
12PIM22.32698380
13TESK22.18771472
14VRK12.16489697
15MYLK1.97247820
16NME11.93620069
17ZAK1.90196294
18DYRK21.85318371
19MUSK1.78122219
20MAP4K21.77280443
21PHKG11.75692178
22PHKG21.75692178
23TESK11.71887985
24BRAF1.68340262
25SRPK11.67080370
26EIF2AK31.56785568
27TLK11.56567076
28MAP3K111.36818315
29CDK81.31013582
30TRIM281.30851461
31BRSK21.27403944
32ABL21.25218320
33CSNK1G21.25214735
34BMPR1B1.23865530
35CDC71.23826451
36ILK1.20156028
37KDR1.19925155
38STK38L1.18957419
39IRAK31.18804761
40MST41.18272251
41BLK1.15504811
42PLK11.13647476
43TSSK61.12460920
44MAP2K71.10644629
45CSNK1G11.09954879
46AURKA1.08013100
47DAPK11.07073960
48TAOK21.05840544
49TTK1.03519267
50BMPR21.02341565
51NEK11.01687090
52DYRK31.01488457
53BCR1.00537994
54CSNK1A1L0.98306617
55CDK190.95512570
56GRK10.94666319
57MAP2K60.91412165
58PLK30.91037865
59AURKB0.90995560
60PAK10.90545766
61DAPK30.89526389
62STK40.89119312
63STK240.88977131
64TXK0.86177743
65MOS0.84885015
66ACVR1B0.84425660
67IRAK40.84353078
68WNK40.84345145
69EIF2AK20.82587686
70RPS6KB20.78952045
71IKBKB0.78739726
72CCNB10.78737118
73INSRR0.78156096
74BRSK10.73556407
75MAP4K10.72816959
76RPS6KA40.71765036
77CAMK2G0.69953465
78ERBB40.69695311
79MARK10.69671280
80PRKD30.67656686
81CHEK20.67394381
82CDK70.66572308
83NUAK10.66304483
84TBK10.66294461
85CSNK2A10.65836784
86MAP3K140.65081744
87EPHB20.64973052
88STK100.64130185
89TYK20.63801081
90PIM10.62648345
91RPS6KA50.62495214
92RAF10.62402005
93PKN10.61751296
94PRKCI0.60963960
95MAP3K80.60642165
96MKNK10.58620415
97NEK20.57005839
98PRKCG0.54676957
99LRRK20.53481246
100MINK10.53407756
101WNK30.52908604
102LMTK20.52898492
103TRPM70.51630169
104MAP3K120.49729635
105ADRBK20.49124995
106MAPK130.49112965
107MELK0.48666563
108CAMK2D0.48240527
109MARK30.47271428
110YES10.46645819
111PDK20.46290524
112EPHA20.45986881
113LATS20.45712234
114CAMK2A0.45325110
115ROCK20.44574092
116CLK10.44013594
117TAOK10.43519283
118BCKDK0.43364726
119CDK140.43279002
120MAPKAPK30.43119035
121CSNK2A20.42075898
122GRK50.41458761
123CSNK1A10.40739419
124GRK70.40666787
125JAK30.40302590
126SIK30.39593148
127ATR0.39345015
128CAMKK20.39012805
129MAP2K30.38588582
130MAPKAPK50.37160121
131MAP3K50.35614471
132MAPKAPK20.34871245
133PLK20.34860843
134PAK40.34074479
135PAK30.33161314
136PRKACA0.32806427
137PINK10.32591377
138TEC0.32215587
139ADRBK10.31393906
140CSNK1G30.30624977

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.81842224
2Ribosome_Homo sapiens_hsa030104.18843037
3Oxidative phosphorylation_Homo sapiens_hsa001903.88984901
4RNA polymerase_Homo sapiens_hsa030203.61433118
5Parkinsons disease_Homo sapiens_hsa050123.56074851
6DNA replication_Homo sapiens_hsa030303.03042257
7Huntingtons disease_Homo sapiens_hsa050162.76387904
8Mismatch repair_Homo sapiens_hsa034302.74710001
9Pyrimidine metabolism_Homo sapiens_hsa002402.39068210
10Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.33560526
11Alzheimers disease_Homo sapiens_hsa050102.31962927
12Homologous recombination_Homo sapiens_hsa034402.31137703
13Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.21341010
14Base excision repair_Homo sapiens_hsa034102.20016154
15Nucleotide excision repair_Homo sapiens_hsa034202.16832370
16Spliceosome_Homo sapiens_hsa030402.07655150
17Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.98687567
18Protein export_Homo sapiens_hsa030601.92948685
19Cardiac muscle contraction_Homo sapiens_hsa042601.90611986
20Basal transcription factors_Homo sapiens_hsa030221.81838062
21RNA transport_Homo sapiens_hsa030131.78022009
22RNA degradation_Homo sapiens_hsa030181.59371411
23Cell cycle_Homo sapiens_hsa041101.54008743
24Sulfur metabolism_Homo sapiens_hsa009201.52115527
25Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.39874465
26Purine metabolism_Homo sapiens_hsa002301.29112612
27Fanconi anemia pathway_Homo sapiens_hsa034601.28790307
28Graft-versus-host disease_Homo sapiens_hsa053321.16137760
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.13096497
30Allograft rejection_Homo sapiens_hsa053301.11011970
31Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.09963010
32Epstein-Barr virus infection_Homo sapiens_hsa051691.09673595
33One carbon pool by folate_Homo sapiens_hsa006701.07321460
34Non-homologous end-joining_Homo sapiens_hsa034501.02482580
35Synaptic vesicle cycle_Homo sapiens_hsa047211.02199124
36Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.01801665
37Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.97256729
38p53 signaling pathway_Homo sapiens_hsa041150.95258184
39Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.93171370
40Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.89320074
41Peroxisome_Homo sapiens_hsa041460.88463078
42Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.87932209
43Folate biosynthesis_Homo sapiens_hsa007900.87725325
44Glutathione metabolism_Homo sapiens_hsa004800.87721435
45Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.86084509
46Legionellosis_Homo sapiens_hsa051340.79401329
47Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.79189796
48Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.78579545
49Rheumatoid arthritis_Homo sapiens_hsa053230.75015902
50Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.72530149
51Herpes simplex infection_Homo sapiens_hsa051680.72080959
52Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.71385415
53Arachidonic acid metabolism_Homo sapiens_hsa005900.68176759
54NOD-like receptor signaling pathway_Homo sapiens_hsa046210.66241286
55Pentose phosphate pathway_Homo sapiens_hsa000300.65883800
56Propanoate metabolism_Homo sapiens_hsa006400.65627782
57Steroid biosynthesis_Homo sapiens_hsa001000.64329762
58SNARE interactions in vesicular transport_Homo sapiens_hsa041300.63606409
59Butanoate metabolism_Homo sapiens_hsa006500.59865580
60Phototransduction_Homo sapiens_hsa047440.58942436
61Sulfur relay system_Homo sapiens_hsa041220.58321097
62Regulation of autophagy_Homo sapiens_hsa041400.57308013
63Autoimmune thyroid disease_Homo sapiens_hsa053200.56419566
64Asthma_Homo sapiens_hsa053100.56274842
65Metabolic pathways_Homo sapiens_hsa011000.55553916
66Carbon metabolism_Homo sapiens_hsa012000.55256795
67Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.54978435
68Intestinal immune network for IgA production_Homo sapiens_hsa046720.54211427
69Drug metabolism - other enzymes_Homo sapiens_hsa009830.53546343
70Vitamin B6 metabolism_Homo sapiens_hsa007500.53043475
71Leishmaniasis_Homo sapiens_hsa051400.53002102
72NF-kappa B signaling pathway_Homo sapiens_hsa040640.51949083
732-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.50524798
74Shigellosis_Homo sapiens_hsa051310.50054360
75Tryptophan metabolism_Homo sapiens_hsa003800.50008572
76Measles_Homo sapiens_hsa051620.47483931
77Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.47478698
78Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.47280647
79Type I diabetes mellitus_Homo sapiens_hsa049400.47138194
80Selenocompound metabolism_Homo sapiens_hsa004500.46728062
81Maturity onset diabetes of the young_Homo sapiens_hsa049500.46288920
82N-Glycan biosynthesis_Homo sapiens_hsa005100.45471922
83Tyrosine metabolism_Homo sapiens_hsa003500.45391086
84Collecting duct acid secretion_Homo sapiens_hsa049660.45289470
85Linoleic acid metabolism_Homo sapiens_hsa005910.45131858
86Primary bile acid biosynthesis_Homo sapiens_hsa001200.44465633
87Cysteine and methionine metabolism_Homo sapiens_hsa002700.43789801
88Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.43274471
89mRNA surveillance pathway_Homo sapiens_hsa030150.43007763
90Chemical carcinogenesis_Homo sapiens_hsa052040.40886161
91Hematopoietic cell lineage_Homo sapiens_hsa046400.40807692
92RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.40384887
93Fructose and mannose metabolism_Homo sapiens_hsa000510.40137055
94Apoptosis_Homo sapiens_hsa042100.39987821
95Biosynthesis of amino acids_Homo sapiens_hsa012300.39565038
96Phenylalanine metabolism_Homo sapiens_hsa003600.39051305
97Viral myocarditis_Homo sapiens_hsa054160.38824528
98Fatty acid elongation_Homo sapiens_hsa000620.38759610
99Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.38085034
100Systemic lupus erythematosus_Homo sapiens_hsa053220.37773463
101beta-Alanine metabolism_Homo sapiens_hsa004100.37708820
102Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.37167812
103Phagosome_Homo sapiens_hsa041450.37030500
104Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.36365612
105Primary immunodeficiency_Homo sapiens_hsa053400.35764718
106Salmonella infection_Homo sapiens_hsa051320.35587159
107Caffeine metabolism_Homo sapiens_hsa002320.35314270
108Mineral absorption_Homo sapiens_hsa049780.35002462
109Ether lipid metabolism_Homo sapiens_hsa005650.34921953
110Antigen processing and presentation_Homo sapiens_hsa046120.34789893
111Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.33725120
112Malaria_Homo sapiens_hsa051440.33199909
113Pentose and glucuronate interconversions_Homo sapiens_hsa000400.33002663
114Viral carcinogenesis_Homo sapiens_hsa052030.32906774
115Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.32572361
116Vibrio cholerae infection_Homo sapiens_hsa051100.32014015
117Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.31264270
118Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.31253033
119Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.29862178
120Oocyte meiosis_Homo sapiens_hsa041140.29647564
121Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.29325190
122Lysosome_Homo sapiens_hsa041420.28663226
123HIF-1 signaling pathway_Homo sapiens_hsa040660.28661398
124Cyanoamino acid metabolism_Homo sapiens_hsa004600.28282083
125Influenza A_Homo sapiens_hsa051640.26772361
126Fatty acid metabolism_Homo sapiens_hsa012120.26466259
127Galactose metabolism_Homo sapiens_hsa000520.26260429
128TGF-beta signaling pathway_Homo sapiens_hsa043500.25428939
129HTLV-I infection_Homo sapiens_hsa051660.24730717
130Pertussis_Homo sapiens_hsa051330.24195942
131alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.22364611
132Arginine and proline metabolism_Homo sapiens_hsa003300.22311591
133Pyruvate metabolism_Homo sapiens_hsa006200.17599405

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