FAM86B3P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1detection of light stimulus involved in sensory perception (GO:0050962)4.61110662
2detection of light stimulus involved in visual perception (GO:0050908)4.61110662
3behavioral response to nicotine (GO:0035095)4.47130436
4meiotic chromosome segregation (GO:0045132)4.40766821
5cilium or flagellum-dependent cell motility (GO:0001539)4.35010062
6cellular response to ATP (GO:0071318)4.20243548
7respiratory chain complex IV assembly (GO:0008535)3.93565260
8DNA strand renaturation (GO:0000733)3.86408072
9rRNA catabolic process (GO:0016075)3.85095334
10somatic hypermutation of immunoglobulin genes (GO:0016446)3.82002990
11somatic diversification of immune receptors via somatic mutation (GO:0002566)3.82002990
12reciprocal DNA recombination (GO:0035825)3.78957901
13reciprocal meiotic recombination (GO:0007131)3.78957901
14DNA deamination (GO:0045006)3.76503341
15tryptophan catabolic process (GO:0006569)3.75526819
16indole-containing compound catabolic process (GO:0042436)3.75526819
17indolalkylamine catabolic process (GO:0046218)3.75526819
18epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.72139020
19response to pheromone (GO:0019236)3.69156422
20kynurenine metabolic process (GO:0070189)3.63821271
21cytochrome complex assembly (GO:0017004)3.60246448
22tRNA modification (GO:0006400)3.50383224
23detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.42412996
24replication fork processing (GO:0031297)3.41819558
25indolalkylamine metabolic process (GO:0006586)3.37999119
26rRNA methylation (GO:0031167)3.37548340
27DNA replication checkpoint (GO:0000076)3.37343766
28L-fucose catabolic process (GO:0042355)3.30675382
29fucose catabolic process (GO:0019317)3.30675382
30L-fucose metabolic process (GO:0042354)3.30675382
31rRNA modification (GO:0000154)3.30607102
32tryptophan metabolic process (GO:0006568)3.24091477
33regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.20297379
34regulation of mitotic spindle checkpoint (GO:1903504)3.20297379
35regulation of nuclear cell cycle DNA replication (GO:0033262)3.19013354
36peptidyl-histidine modification (GO:0018202)3.10859528
37epithelial cilium movement (GO:0003351)3.10620959
38pseudouridine synthesis (GO:0001522)3.09713331
39mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.08649382
40mitochondrial respiratory chain complex I assembly (GO:0032981)3.08649382
41NADH dehydrogenase complex assembly (GO:0010257)3.08649382
42amine catabolic process (GO:0009310)3.08355642
43cellular biogenic amine catabolic process (GO:0042402)3.08355642
44regulation of hippo signaling (GO:0035330)3.07650357
45organic cation transport (GO:0015695)3.06799793
46mitochondrial RNA metabolic process (GO:0000959)3.04885857
47RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.04071957
48tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.04071957
49RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.02700541
50preassembly of GPI anchor in ER membrane (GO:0016254)3.01915417
51transepithelial transport (GO:0070633)3.00611946
52base-excision repair, AP site formation (GO:0006285)2.99779606
53negative regulation of telomere maintenance (GO:0032205)2.99736219
54mitochondrial respiratory chain complex assembly (GO:0033108)2.99141848
55ubiquinone biosynthetic process (GO:0006744)2.98614184
56mannosylation (GO:0097502)2.98121844
57recombinational repair (GO:0000725)2.97497285
58L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.97386593
59photoreceptor cell maintenance (GO:0045494)2.96434108
60motile cilium assembly (GO:0044458)2.96343729
61double-strand break repair via homologous recombination (GO:0000724)2.95798103
62protein complex biogenesis (GO:0070271)2.92935041
63regulation of posttranscriptional gene silencing (GO:0060147)2.91640190
64regulation of gene silencing by miRNA (GO:0060964)2.91640190
65regulation of gene silencing by RNA (GO:0060966)2.91640190
66cell wall macromolecule catabolic process (GO:0016998)2.87453199
67tRNA processing (GO:0008033)2.85109188
68negative regulation of translation, ncRNA-mediated (GO:0040033)2.83677981
69regulation of translation, ncRNA-mediated (GO:0045974)2.83677981
70negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.83677981
71auditory receptor cell stereocilium organization (GO:0060088)2.82285364
72NAD biosynthetic process (GO:0009435)2.79361448
73cilium movement (GO:0003341)2.78832918
74sulfation (GO:0051923)2.75373586
75DNA double-strand break processing (GO:0000729)2.74388469
76cilium organization (GO:0044782)2.73574789
77ncRNA catabolic process (GO:0034661)2.71987803
78axoneme assembly (GO:0035082)2.71035380
79sperm motility (GO:0030317)2.69491680
80pantothenate metabolic process (GO:0015939)2.69388289
81snRNA transcription (GO:0009301)2.68782711
82DNA methylation involved in gamete generation (GO:0043046)2.68007262
83multicellular organism reproduction (GO:0032504)2.67564061
84mitotic cell cycle arrest (GO:0071850)2.65996540
85cilium assembly (GO:0042384)2.65992869
86purinergic nucleotide receptor signaling pathway (GO:0035590)2.64734364
87cell wall macromolecule metabolic process (GO:0044036)2.64294958
88maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.64055602
89pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.63876343
90axonemal dynein complex assembly (GO:0070286)2.63036909
91ubiquinone metabolic process (GO:0006743)2.61388919
92nephron epithelium morphogenesis (GO:0072088)2.58333781
93nephron tubule morphogenesis (GO:0072078)2.58333781
94regulation of centriole replication (GO:0046599)2.57445719
95hematopoietic stem cell proliferation (GO:0071425)2.56687575
96regulation of cilium movement (GO:0003352)2.55434008
97L-methionine biosynthetic process (GO:0071265)2.54980017
98amino acid salvage (GO:0043102)2.54980017
99L-methionine salvage (GO:0071267)2.54980017
100maturation of 5.8S rRNA (GO:0000460)2.54757655

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ZNF274_21170338_ChIP-Seq_K562_Hela3.99398679
2MYCN_21190229_ChIP-Seq_SHEP-21N_Human3.43550188
3NOTCH1_21737748_ChIP-Seq_TLL_Human3.12049780
4HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.07633968
5GABP_17652178_ChIP-ChIP_JURKAT_Human2.91068426
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.88765221
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.82480812
8EST1_17652178_ChIP-ChIP_JURKAT_Human2.69524638
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.67435258
10VDR_22108803_ChIP-Seq_LS180_Human2.61730843
11HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.51067167
12CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.50643987
13KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.39408711
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.15487015
15VDR_23849224_ChIP-Seq_CD4+_Human2.11863220
16CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.05276187
17GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.04528115
18E2F7_22180533_ChIP-Seq_HELA_Human2.04482897
19FOXP3_21729870_ChIP-Seq_TREG_Human1.93863172
20IGF1R_20145208_ChIP-Seq_DFB_Human1.92618773
21EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.85204274
22MYC_18940864_ChIP-ChIP_HL60_Human1.81691184
23E2F4_17652178_ChIP-ChIP_JURKAT_Human1.80751331
24SRF_21415370_ChIP-Seq_HL-1_Mouse1.80299320
25NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.77315027
26ERA_21632823_ChIP-Seq_H3396_Human1.76158097
27PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.75283142
28EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.70459433
29CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.69057466
30EGR1_23403033_ChIP-Seq_LIVER_Mouse1.61018221
31GABP_19822575_ChIP-Seq_HepG2_Human1.60755370
32EWS_26573619_Chip-Seq_HEK293_Human1.60503126
33TP53_22573176_ChIP-Seq_HFKS_Human1.60369607
34E2F1_20622854_ChIP-Seq_HELA_Human1.59659722
35GATA3_21878914_ChIP-Seq_MCF-7_Human1.54465054
36RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.52493070
37CIITA_25753668_ChIP-Seq_RAJI_Human1.50462231
38RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.50072843
39KDM5A_27292631_Chip-Seq_BREAST_Human1.49964952
40XRN2_22483619_ChIP-Seq_HELA_Human1.47634153
41FUS_26573619_Chip-Seq_HEK293_Human1.46823649
42SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.45162625
43ER_23166858_ChIP-Seq_MCF-7_Human1.43260229
44ELK1_19687146_ChIP-ChIP_HELA_Human1.41101133
45SALL1_21062744_ChIP-ChIP_HESCs_Human1.39026644
46IRF1_19129219_ChIP-ChIP_H3396_Human1.38869246
47BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.35708647
48P68_20966046_ChIP-Seq_HELA_Human1.35526215
49PHF8_20622854_ChIP-Seq_HELA_Human1.35497840
50OCT4_20526341_ChIP-Seq_ESCs_Human1.33535280
51YY1_22570637_ChIP-Seq_MALME-3M_Human1.32667042
52RAC3_21632823_ChIP-Seq_H3396_Human1.30664526
53DCP1A_22483619_ChIP-Seq_HELA_Human1.29308134
54TP63_19390658_ChIP-ChIP_HaCaT_Human1.28352339
55NANOG_20526341_ChIP-Seq_ESCs_Human1.27460246
56YY1_21170310_ChIP-Seq_MESCs_Mouse1.26981180
57TTF2_22483619_ChIP-Seq_HELA_Human1.26645394
58P53_21459846_ChIP-Seq_SAOS-2_Human1.24961333
59MYC_19829295_ChIP-Seq_ESCs_Human1.22921571
60FOXA1_25329375_ChIP-Seq_VCAP_Human1.22207964
61FOXA1_27270436_Chip-Seq_PROSTATE_Human1.22207964
62BCL6_27268052_Chip-Seq_Bcells_Human1.22183669
63PADI4_21655091_ChIP-ChIP_MCF-7_Human1.21240341
64AR_20517297_ChIP-Seq_VCAP_Human1.21043695
65FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.20243547
66E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.19610864
67FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.18756078
68TAF2_19829295_ChIP-Seq_ESCs_Human1.17237224
69BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.16048593
70P300_27268052_Chip-Seq_Bcells_Human1.15904793
71FOXP1_21924763_ChIP-Seq_HESCs_Human1.14998631
72CTBP1_25329375_ChIP-Seq_LNCAP_Human1.13648502
73VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.12847903
74SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.11524361
75FLI1_27457419_Chip-Seq_LIVER_Mouse1.11322547
76CTBP2_25329375_ChIP-Seq_LNCAP_Human1.11234517
77NCOR_22424771_ChIP-Seq_293T_Human1.10568314
78CTCF_20526341_ChIP-Seq_ESCs_Human1.10478821
79BCOR_27268052_Chip-Seq_Bcells_Human1.09122009
80HOXB7_26014856_ChIP-Seq_BT474_Human1.09005761
81WDR5_24793694_ChIP-Seq_LNCAP_Human1.08750927
82CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.06175325
83TDRD3_21172665_ChIP-Seq_MCF-7_Human1.05027034
84MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.04822576
85CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.03301647
86FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.01918478
87PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.01702606
88GBX2_23144817_ChIP-Seq_PC3_Human0.98898287
89MAF_26560356_Chip-Seq_TH2_Human0.97615844
90ELF1_20517297_ChIP-Seq_JURKAT_Human0.96267879
91HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.94810317
92GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.93190418
93ETV2_25802403_ChIP-Seq_MESCs_Mouse0.91957609
94TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.90200727
95RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.89403945
96RARB_24833708_ChIP-Seq_LIVER_Mouse0.87883839
97EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.87390739
98E2F1_17053090_ChIP-ChIP_MCF-7_Human0.85955391
99MYC_18358816_ChIP-ChIP_MESCs_Mouse0.85480755
100MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.84880649

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color3.41810074
2MP0008875_abnormal_xenobiotic_pharmacok3.33576854
3MP0001986_abnormal_taste_sensitivity3.30754770
4MP0006292_abnormal_olfactory_placode3.19570610
5MP0005083_abnormal_biliary_tract3.03784949
6MP0003195_calcinosis2.87653513
7MP0008058_abnormal_DNA_repair2.56257656
8MP0005174_abnormal_tail_pigmentation2.50149628
9MP0008877_abnormal_DNA_methylation2.39784645
10MP0005551_abnormal_eye_electrophysiolog2.36305999
11MP0003878_abnormal_ear_physiology2.24361099
12MP0005377_hearing/vestibular/ear_phenot2.24361099
13MP0010094_abnormal_chromosome_stability2.05146214
14MP0005410_abnormal_fertilization1.98073539
15MP0001661_extended_life_span1.82198309
16MP0008995_early_reproductive_senescence1.80872871
17MP0003718_maternal_effect1.76445309
18MP0008872_abnormal_physiological_respon1.74114148
19MP0005171_absent_coat_pigmentation1.69860388
20MP0004147_increased_porphyrin_level1.67161510
21MP0003890_abnormal_embryonic-extraembry1.67082731
22MP0002653_abnormal_ependyma_morphology1.66988306
23MP0000569_abnormal_digit_pigmentation1.65208405
24MP0003693_abnormal_embryo_hatching1.64571530
25MP0005084_abnormal_gallbladder_morpholo1.61070958
26MP0006072_abnormal_retinal_apoptosis1.59802996
27MP0003111_abnormal_nucleus_morphology1.59552953
28MP0002132_abnormal_respiratory_system1.53341119
29MP0005253_abnormal_eye_physiology1.51642620
30MP0002938_white_spotting1.50928731
31MP0001324_abnormal_eye_pigmentation1.48950608
32MP0001968_abnormal_touch/_nociception1.48366897
33MP0005646_abnormal_pituitary_gland1.45739804
34MP0003646_muscle_fatigue1.41423197
35MP0004133_heterotaxia1.39618211
36MP0002928_abnormal_bile_duct1.39407222
37MP0001485_abnormal_pinna_reflex1.38923573
38MP0001293_anophthalmia1.35694146
39MP0009046_muscle_twitch1.32826808
40MP0002160_abnormal_reproductive_system1.31665437
41MP0000631_abnormal_neuroendocrine_gland1.30784242
42MP0001929_abnormal_gametogenesis1.25736510
43MP0005423_abnormal_somatic_nervous1.25695227
44MP0000015_abnormal_ear_pigmentation1.25333203
45MP0002396_abnormal_hematopoietic_system1.25146533
46MP0001873_stomach_inflammation1.24701622
47MP0003698_abnormal_male_reproductive1.21793813
48MP0002102_abnormal_ear_morphology1.16279787
49MP0004142_abnormal_muscle_tone1.15565105
50MP0001529_abnormal_vocalization1.15540257
51MP0005075_abnormal_melanosome_morpholog1.15013959
52MP0003172_abnormal_lysosome_physiology1.13756162
53MP0003786_premature_aging1.11327223
54MP0010030_abnormal_orbit_morphology1.08306805
55MP0003119_abnormal_digestive_system1.07152786
56MP0006276_abnormal_autonomic_nervous1.05100530
57MP0002210_abnormal_sex_determination1.04747175
58MP0002234_abnormal_pharynx_morphology1.03733620
59MP0006035_abnormal_mitochondrial_morpho1.03343914
60MP0001764_abnormal_homeostasis1.02172085
61MP0000427_abnormal_hair_cycle1.00391626
62MP0002735_abnormal_chemical_nociception0.98236705
63MP0008789_abnormal_olfactory_epithelium0.97820787
64MP0003567_abnormal_fetal_cardiomyocyte0.95843200
65MP0000049_abnormal_middle_ear0.95770456
66MP0000470_abnormal_stomach_morphology0.95165703
67MP0005365_abnormal_bile_salt0.94949539
68MP0001145_abnormal_male_reproductive0.93480090
69MP0008007_abnormal_cellular_replicative0.93131718
70MP0000383_abnormal_hair_follicle0.93045888
71MP0001502_abnormal_circadian_rhythm0.91071312
72MP0006036_abnormal_mitochondrial_physio0.90237476
73MP0002876_abnormal_thyroid_physiology0.89554328
74MP0003077_abnormal_cell_cycle0.88840774
75MP0008057_abnormal_DNA_replication0.88414620
76MP0004043_abnormal_pH_regulation0.88192753
77MP0009278_abnormal_bone_marrow0.87838762
78MP0002736_abnormal_nociception_after0.87834146
79MP0005389_reproductive_system_phenotype0.87337418
80MP0005195_abnormal_posterior_eye0.85883024
81MP0005395_other_phenotype0.84357801
82MP0005391_vision/eye_phenotype0.81421792
83MP0000653_abnormal_sex_gland0.81299421
84MP0005332_abnormal_amino_acid0.80513854
85MP0005220_abnormal_exocrine_pancreas0.80341711
86MP0002138_abnormal_hepatobiliary_system0.79682042
87MP0001919_abnormal_reproductive_system0.76551910
88MP0000230_abnormal_systemic_arterial0.74388386
89MP0005394_taste/olfaction_phenotype0.71802487
90MP0005499_abnormal_olfactory_system0.71802487
91MP0003806_abnormal_nucleotide_metabolis0.69817298
92MP0002837_dystrophic_cardiac_calcinosis0.69695340
93MP0003137_abnormal_impulse_conducting0.68026344
94MP0001984_abnormal_olfaction0.67249430
95MP0005360_urolithiasis0.65636335
96MP0004808_abnormal_hematopoietic_stem0.65078774
97MP0002752_abnormal_somatic_nervous0.64462412
98MP0001905_abnormal_dopamine_level0.63893780
99MP0004130_abnormal_muscle_cell0.63369634
100MP0003787_abnormal_imprinting0.63042121

Predicted human phenotypes

RankGene SetZ-score
1Attenuation of retinal blood vessels (HP:0007843)4.19102791
2Molar tooth sign on MRI (HP:0002419)4.13155230
3Abnormality of midbrain morphology (HP:0002418)4.13155230
4Pancreatic fibrosis (HP:0100732)4.06203684
5Congenital stationary night blindness (HP:0007642)4.05754753
6Pancreatic cysts (HP:0001737)4.02614045
7True hermaphroditism (HP:0010459)3.76319110
8Rib fusion (HP:0000902)3.50404581
9Nephronophthisis (HP:0000090)3.36491249
10Chronic hepatic failure (HP:0100626)3.17184780
11Decreased electroretinogram (ERG) amplitude (HP:0000654)3.14834291
12Bony spicule pigmentary retinopathy (HP:0007737)3.08646414
13Chromsome breakage (HP:0040012)3.08255100
14Decreased central vision (HP:0007663)3.02479491
15Cystic liver disease (HP:0006706)2.99803015
16Abnormality of DNA repair (HP:0003254)2.92304674
17Chromosomal breakage induced by crosslinking agents (HP:0003221)2.89137873
18Cerebellar dysplasia (HP:0007033)2.83860536
19Patellar aplasia (HP:0006443)2.75907788
20Abnormal biliary tract physiology (HP:0012439)2.71304589
21Bile duct proliferation (HP:0001408)2.71304589
22Abnormality of the renal medulla (HP:0100957)2.70804354
23Absent thumb (HP:0009777)2.69164998
24Abnormal rod and cone electroretinograms (HP:0008323)2.67788918
25Hypoplasia of the pons (HP:0012110)2.67095208
26Absent/shortened dynein arms (HP:0200106)2.66588402
27Dynein arm defect of respiratory motile cilia (HP:0012255)2.66588402
28Squamous cell carcinoma (HP:0002860)2.63674442
29Aplasia/Hypoplasia of the patella (HP:0006498)2.57715036
30Abnormality of the pons (HP:0007361)2.55296861
31Birth length less than 3rd percentile (HP:0003561)2.52381966
32Aplasia/Hypoplasia of the uvula (HP:0010293)2.52026131
33Abolished electroretinogram (ERG) (HP:0000550)2.48393673
34Absent rod-and cone-mediated responses on ERG (HP:0007688)2.47047780
35Type II lissencephaly (HP:0007260)2.43260391
36Duplicated collecting system (HP:0000081)2.42180277
37Sclerocornea (HP:0000647)2.40040547
38Abnormality of the renal collecting system (HP:0004742)2.39307554
39Tubular atrophy (HP:0000092)2.35390806
40Abnormality of alanine metabolism (HP:0010916)2.33412498
41Hyperalaninemia (HP:0003348)2.33412498
42Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.33412498
43Poikiloderma (HP:0001029)2.32156447
44Abnormality of the ileum (HP:0001549)2.31937386
45Meckel diverticulum (HP:0002245)2.29503452
46Congenital hepatic fibrosis (HP:0002612)2.28271224
47Dyschromatopsia (HP:0007641)2.25771691
48Abnormal respiratory epithelium morphology (HP:0012253)2.21821529
49Abnormal respiratory motile cilium morphology (HP:0005938)2.21821529
50Abnormal drinking behavior (HP:0030082)2.18889123
51Polydipsia (HP:0001959)2.18889123
52Sloping forehead (HP:0000340)2.17245345
53Anencephaly (HP:0002323)2.11966346
54Abnormal number of erythroid precursors (HP:0012131)2.07066450
55Hepatocellular necrosis (HP:0001404)2.06306102
56Pendular nystagmus (HP:0012043)2.05867019
57Colon cancer (HP:0003003)2.05666960
58Rectovaginal fistula (HP:0000143)2.05227967
59Rectal fistula (HP:0100590)2.05227967
60Mesangial abnormality (HP:0001966)2.03626070
61Aplasia/Hypoplasia of the tongue (HP:0010295)2.02167648
62Postaxial foot polydactyly (HP:0001830)2.01638262
63Anophthalmia (HP:0000528)1.99295195
64Inability to walk (HP:0002540)1.98769834
65Clubbing of toes (HP:0100760)1.97936451
66Aplasia/Hypoplasia of the spleen (HP:0010451)1.96940739
67Abnormal ciliary motility (HP:0012262)1.96864476
68Ectopic kidney (HP:0000086)1.96366029
69Intestinal fistula (HP:0100819)1.93764650
70Lipid accumulation in hepatocytes (HP:0006561)1.93035687
71Optic nerve coloboma (HP:0000588)1.92816251
72Progressive inability to walk (HP:0002505)1.92191539
73Partial agenesis of the corpus callosum (HP:0001338)1.92023516
7411 pairs of ribs (HP:0000878)1.90600643
75Male pseudohermaphroditism (HP:0000037)1.90251248
76Short thumb (HP:0009778)1.87550286
77Protruding tongue (HP:0010808)1.87235066
78Severe visual impairment (HP:0001141)1.86790660
79Oligohydramnios (HP:0001562)1.85694531
80Abnormality of chromosome stability (HP:0003220)1.85687113
81Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.84348081
82Abnormal protein N-linked glycosylation (HP:0012347)1.84348081
83Abnormal protein glycosylation (HP:0012346)1.84348081
84Abnormal glycosylation (HP:0012345)1.84348081
85Absent radius (HP:0003974)1.82622648
86Large for gestational age (HP:0001520)1.81291514
87Absent forearm bone (HP:0003953)1.81140616
88Aplasia involving forearm bones (HP:0009822)1.81140616
89Abnormality of cells of the erythroid lineage (HP:0012130)1.80675475
90Abnormality of the renal cortex (HP:0011035)1.80266085
91Occipital encephalocele (HP:0002085)1.79319152
92Abnormality of the preputium (HP:0100587)1.78487156
93Reticulocytopenia (HP:0001896)1.78188522
94Abnormal respiratory motile cilium physiology (HP:0012261)1.76468219
95Bilateral microphthalmos (HP:0007633)1.75333010
96Increased CSF lactate (HP:0002490)1.72016271
97Enlarged kidneys (HP:0000105)1.69686409
98Mitochondrial inheritance (HP:0001427)1.69484812
99Small intestinal stenosis (HP:0012848)1.69477179
100Duodenal stenosis (HP:0100867)1.69477179

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TLK14.47592124
2ZAK4.37974606
3FRK4.22360272
4WNK43.01064046
5BMPR1B2.87753513
6STK162.80226504
7ADRBK22.79973723
8INSRR2.54689396
9PDK22.44055094
10MAPK152.41664128
11ACVR1B2.34800087
12GRK12.12151253
13NUAK12.11201676
14MUSK2.07234476
15WNK32.03696196
16VRK22.03449300
17TAOK31.72238356
18NME11.51228331
19CAMKK21.43472168
20BRSK21.39449788
21SIK21.38964929
22NEK21.32356066
23PINK11.30838014
24IKBKB1.29941166
25ATR1.22853105
26MKNK21.22536307
27VRK11.20428813
28CHEK21.14250543
29MAP4K21.13777708
30TXK1.12407817
31CDC71.10751540
32MAP2K21.06838218
33MAPKAPK31.05015505
34RPS6KA51.04213895
35MKNK11.02757039
36BCKDK1.02127688
37CSNK1G31.01884700
38CSNK1A1L1.00313950
39MAPK130.98243235
40CSNK1G10.95262643
41SRPK10.94715515
42CDK120.91207104
43FLT30.90620279
44MAP4K10.84038647
45CDK40.83114606
46ITK0.82631030
47STK390.82047404
48MAPK110.81362066
49WNK10.81062666
50ADRBK10.79129231
51TGFBR10.78983281
52OXSR10.78937748
53PLK40.73187110
54GRK60.70521756
55RPS6KA60.67295385
56MARK30.65870570
57TEC0.65748725
58CSNK1G20.64006540
59TNIK0.63484905
60DYRK20.63479582
61PRKCQ0.61502941
62MAPKAPK50.59195390
63PLK10.57233025
64BTK0.57042880
65RAF10.56888688
66BUB10.54773996
67DAPK20.53409663
68ATM0.51145155
69CAMK1D0.49843045
70TRIM280.49655551
71SYK0.49316974
72AKT30.49015522
73CDK80.48573276
74CCNB10.48084175
75BLK0.47148859
76EIF2AK30.46279256
77PIM10.45346741
78PRKAA10.45035434
79STK110.44460093
80PTK2B0.43956887
81PIM20.43248206
82CAMKK10.42014085
83IRAK10.39259661
84NTRK30.38003819
85MAP2K60.35903574
86RPS6KB20.33994829
87MELK0.33350506
88AURKA0.32503923
89MAP3K70.31850486
90TNK20.31148163
91RPS6KA10.31142270
92JAK30.30893691
93CAMK1G0.30875671
94CSNK1D0.30572871
95AKT10.27966611
96RPS6KL10.27805734
97RPS6KC10.27805734
98PRKACA0.26247304
99PRKAA20.25775597
100LYN0.24577674

Predicted pathways (KEGG)

RankGene SetZ-score
1Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001303.49727954
2Selenocompound metabolism_Homo sapiens_hsa004503.39770458
3Homologous recombination_Homo sapiens_hsa034403.28693582
4Fanconi anemia pathway_Homo sapiens_hsa034603.07210275
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.67553736
6Nitrogen metabolism_Homo sapiens_hsa009102.67042423
7RNA polymerase_Homo sapiens_hsa030202.56907856
8Phototransduction_Homo sapiens_hsa047442.40234433
9One carbon pool by folate_Homo sapiens_hsa006702.29228134
10Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.10984743
11alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.08087114
12Linoleic acid metabolism_Homo sapiens_hsa005911.97384449
13Base excision repair_Homo sapiens_hsa034101.89009597
14Butanoate metabolism_Homo sapiens_hsa006501.87504953
15Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.76467459
16Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.68625257
17Non-homologous end-joining_Homo sapiens_hsa034501.65718855
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.65389150
19Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.65090867
20Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.63376811
21Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.63083306
22Sulfur relay system_Homo sapiens_hsa041221.62702882
23Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.62660273
24Basal transcription factors_Homo sapiens_hsa030221.55029935
25DNA replication_Homo sapiens_hsa030301.54899520
26Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.54676309
27Olfactory transduction_Homo sapiens_hsa047401.54486953
28Taste transduction_Homo sapiens_hsa047421.53751329
29RNA degradation_Homo sapiens_hsa030181.51438640
30Ribosome_Homo sapiens_hsa030101.42837899
31Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.34557778
32Mismatch repair_Homo sapiens_hsa034301.25644332
33Ether lipid metabolism_Homo sapiens_hsa005651.24392345
34Pyrimidine metabolism_Homo sapiens_hsa002401.24345720
35Nucleotide excision repair_Homo sapiens_hsa034201.18372671
36Glycerolipid metabolism_Homo sapiens_hsa005611.18012040
37Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.17598062
38Tryptophan metabolism_Homo sapiens_hsa003801.16416546
39Lysine degradation_Homo sapiens_hsa003101.16051072
40ABC transporters_Homo sapiens_hsa020101.15785223
41Purine metabolism_Homo sapiens_hsa002301.15746696
42Systemic lupus erythematosus_Homo sapiens_hsa053221.14768203
43Vitamin digestion and absorption_Homo sapiens_hsa049771.10261533
44Maturity onset diabetes of the young_Homo sapiens_hsa049501.07614795
45RNA transport_Homo sapiens_hsa030131.07534039
46Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.06967003
47Peroxisome_Homo sapiens_hsa041461.06894963
48Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.91533037
49Chemical carcinogenesis_Homo sapiens_hsa052040.90953182
50Primary immunodeficiency_Homo sapiens_hsa053400.90792086
51Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.87471041
52Hedgehog signaling pathway_Homo sapiens_hsa043400.78796066
53Arachidonic acid metabolism_Homo sapiens_hsa005900.77381899
54Spliceosome_Homo sapiens_hsa030400.77109287
55Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.75449054
56Nicotine addiction_Homo sapiens_hsa050330.75317379
57Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.75083057
58Huntingtons disease_Homo sapiens_hsa050160.73336079
59Intestinal immune network for IgA production_Homo sapiens_hsa046720.72706261
60Steroid hormone biosynthesis_Homo sapiens_hsa001400.71347920
61Ovarian steroidogenesis_Homo sapiens_hsa049130.71219591
62Alcoholism_Homo sapiens_hsa050340.70484629
63Metabolic pathways_Homo sapiens_hsa011000.69917121
64Glycerophospholipid metabolism_Homo sapiens_hsa005640.69256063
65Oxidative phosphorylation_Homo sapiens_hsa001900.68846846
66Glycosaminoglycan degradation_Homo sapiens_hsa005310.66876964
67Fat digestion and absorption_Homo sapiens_hsa049750.63162760
68Histidine metabolism_Homo sapiens_hsa003400.63018907
69Caffeine metabolism_Homo sapiens_hsa002320.61630249
70Primary bile acid biosynthesis_Homo sapiens_hsa001200.59621562
71Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.59189230
72N-Glycan biosynthesis_Homo sapiens_hsa005100.56270454
73Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.54311193
74Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.53877136
75Morphine addiction_Homo sapiens_hsa050320.53388324
76Cysteine and methionine metabolism_Homo sapiens_hsa002700.50835308
77Regulation of autophagy_Homo sapiens_hsa041400.48638214
78Parkinsons disease_Homo sapiens_hsa050120.48478272
79beta-Alanine metabolism_Homo sapiens_hsa004100.48319641
80Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.47028644
81Basal cell carcinoma_Homo sapiens_hsa052170.46118596
82Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.44941130
83Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.43949193
84Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.40936795
85Retinol metabolism_Homo sapiens_hsa008300.40738690
86Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.39451285
87Cell cycle_Homo sapiens_hsa041100.35767057
88Serotonergic synapse_Homo sapiens_hsa047260.35005467
89Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.33803223
90Sphingolipid metabolism_Homo sapiens_hsa006000.33581749
91Fatty acid biosynthesis_Homo sapiens_hsa000610.32063901
92Glutathione metabolism_Homo sapiens_hsa004800.30496880
93Calcium signaling pathway_Homo sapiens_hsa040200.30074248
94Steroid biosynthesis_Homo sapiens_hsa001000.29147268
95Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.28353626
96Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.26687362
97Propanoate metabolism_Homo sapiens_hsa006400.26520072
98NOD-like receptor signaling pathway_Homo sapiens_hsa046210.24727388
99Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.22176383
100Carbohydrate digestion and absorption_Homo sapiens_hsa049730.17803228

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »