FAM83E

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axonemal dynein complex assembly (GO:0070286)8.91649651
2cilium or flagellum-dependent cell motility (GO:0001539)7.56941061
3maintenance of gastrointestinal epithelium (GO:0030277)7.10734456
4intestinal epithelial cell development (GO:0060576)7.05143809
5flavonoid metabolic process (GO:0009812)6.99086195
63-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)6.54986538
7purine ribonucleoside bisphosphate metabolic process (GO:0034035)6.54986538
8UDP-N-acetylglucosamine metabolic process (GO:0006047)6.52190012
9regulation of guanylate cyclase activity (GO:0031282)6.46248915
10bundle of His cell to Purkinje myocyte communication (GO:0086069)6.21574415
11motile cilium assembly (GO:0044458)6.14242916
12intestinal absorption (GO:0050892)6.07017114
13cilium movement (GO:0003341)5.98164828
14sulfate transmembrane transport (GO:1902358)5.74240116
15cellular ketone body metabolic process (GO:0046950)5.69170996
16epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)5.62459751
17sulfation (GO:0051923)5.61644244
18epithelial structure maintenance (GO:0010669)5.48131971
19pyrimidine-containing compound transmembrane transport (GO:0072531)5.47832735
20melanin biosynthetic process (GO:0042438)5.28494837
21cGMP-mediated signaling (GO:0019934)5.24894006
22O-glycan processing (GO:0016266)5.22776261
23actin filament depolymerization (GO:0030042)5.17571306
24L-fucose metabolic process (GO:0042354)5.12589527
25L-fucose catabolic process (GO:0042355)5.12589527
26fucose catabolic process (GO:0019317)5.12589527
27epithelial cilium movement (GO:0003351)5.07469249
28positive regulation of guanylate cyclase activity (GO:0031284)4.99502161
29ketone body metabolic process (GO:1902224)4.93647587
30bile acid and bile salt transport (GO:0015721)4.90888832
31sulfur amino acid catabolic process (GO:0000098)4.81572310
32vitamin transmembrane transport (GO:0035461)4.79265184
33sulfate transport (GO:0008272)4.78196206
34oligosaccharide biosynthetic process (GO:0009312)4.71197960
35melanin metabolic process (GO:0006582)4.70785317
36angiotensin maturation (GO:0002003)4.65522861
37calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)4.61147271
38ethanol oxidation (GO:0006069)4.56594536
39axoneme assembly (GO:0035082)4.55210820
40bicarbonate transport (GO:0015701)4.52590705
41nucleotide-sugar biosynthetic process (GO:0009226)4.52367770
42secondary metabolite biosynthetic process (GO:0044550)4.47416946
43hepatocyte apoptotic process (GO:0097284)4.35193476
44positive regulation of respiratory burst (GO:0060267)4.30555601
45regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)4.30535408
46sperm capacitation (GO:0048240)4.25153127
47sulfur compound transport (GO:0072348)4.21701906
48regulation of calcineurin-NFAT signaling cascade (GO:0070884)4.17855327
49digestive system process (GO:0022600)4.05809875
50hemidesmosome assembly (GO:0031581)4.01277629
51cellular glucuronidation (GO:0052695)3.97685295
52antibacterial humoral response (GO:0019731)3.96892829
53regulation of respiratory burst (GO:0060263)3.89671346
54regulation of cGMP biosynthetic process (GO:0030826)3.88890353
55antimicrobial humoral response (GO:0019730)3.87898679
56diol metabolic process (GO:0034311)3.83897640
57glutathione biosynthetic process (GO:0006750)3.78293214
58renal absorption (GO:0070293)3.77403820
59GDP-mannose metabolic process (GO:0019673)3.75887265
60exogenous drug catabolic process (GO:0042738)3.71596268
61glomerular filtration (GO:0003094)3.71078128
62uronic acid metabolic process (GO:0006063)3.66431840
63glucuronate metabolic process (GO:0019585)3.66431840
64regulation of vitamin metabolic process (GO:0030656)3.60229333
65nucleotide-sugar metabolic process (GO:0009225)3.59629087
66epithelial cell-cell adhesion (GO:0090136)3.56339260
67nonribosomal peptide biosynthetic process (GO:0019184)3.53739048
68epoxygenase P450 pathway (GO:0019373)3.53712563
69response to hepatocyte growth factor (GO:0035728)3.52502478
70cellular response to hepatocyte growth factor stimulus (GO:0035729)3.52502478
71lung secretory cell differentiation (GO:0061140)3.51426945
72excretion (GO:0007588)3.49770238
73mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.48297264
74receptor guanylyl cyclase signaling pathway (GO:0007168)3.46419557
75renal filtration (GO:0097205)3.44782923
76fucose metabolic process (GO:0006004)3.44518018
77desmosome organization (GO:0002934)3.43372521
78multicellular organismal water homeostasis (GO:0050891)3.43196421
79phosphatidylcholine biosynthetic process (GO:0006656)3.42687638
80regulation of interferon-beta biosynthetic process (GO:0045357)3.41043685
81negative regulation of T cell differentiation in thymus (GO:0033085)3.39707755
82phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.38576985
83neurotransmitter biosynthetic process (GO:0042136)3.36394237
84regulation of systemic arterial blood pressure by hormone (GO:0001990)3.35808986
85regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)3.35808986
86endocrine process (GO:0050886)3.35808986
87ethanol metabolic process (GO:0006067)3.32165700
88diterpenoid biosynthetic process (GO:0016102)3.30745377
89intestinal cholesterol absorption (GO:0030299)3.29304476
90vitamin A metabolic process (GO:0006776)3.28344985
91thrombin receptor signaling pathway (GO:0070493)3.26401676
92ventricular cardiac muscle cell action potential (GO:0086005)3.25611320
93regulation of cholesterol homeostasis (GO:2000188)3.25535251
94regulation of hydrogen peroxide metabolic process (GO:0010310)3.25261979
95negative regulation of keratinocyte proliferation (GO:0010839)3.23741133
96regulation of viral release from host cell (GO:1902186)3.23478300
97galactose catabolic process (GO:0019388)3.20847933
98glycosylceramide metabolic process (GO:0006677)3.20701889
99sphingomyelin metabolic process (GO:0006684)3.20535000
100drug metabolic process (GO:0017144)3.20231724
101positive regulation of protein kinase C signaling (GO:0090037)3.20118847
102glucose 6-phosphate metabolic process (GO:0051156)3.19806273
103nucleoside bisphosphate metabolic process (GO:0033865)3.19054579
104purine nucleoside bisphosphate metabolic process (GO:0034032)3.19054579
105ribonucleoside bisphosphate metabolic process (GO:0033875)3.19054579
106regulation of cGMP metabolic process (GO:0030823)3.18700494
107protein O-linked glycosylation (GO:0006493)3.18662880
108nucleotide transmembrane transport (GO:1901679)3.17367272
109purine ribonucleotide transport (GO:0015868)3.16084733
110digestion (GO:0007586)3.16008463
111auditory receptor cell differentiation (GO:0042491)3.15547128
112ATP biosynthetic process (GO:0006754)3.13188645
113regulation of cellular extravasation (GO:0002691)3.11620626
114negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)3.09447682
115regulation of chemokine secretion (GO:0090196)3.09382081
116keratinocyte proliferation (GO:0043616)3.08915843
117uterus development (GO:0060065)3.07978862
118positive regulation of epidermal cell differentiation (GO:0045606)3.07167409
119renal system process involved in regulation of blood volume (GO:0001977)3.04537986
120drug catabolic process (GO:0042737)3.04157621
121regulation of cilium movement (GO:0003352)3.03565162
122one-carbon compound transport (GO:0019755)3.03314682
123sphingoid metabolic process (GO:0046519)3.02453155
124energy coupled proton transport, down electrochemical gradient (GO:0015985)3.00976644
125ATP synthesis coupled proton transport (GO:0015986)3.00976644
126lung epithelium development (GO:0060428)2.99787739
127fucosylation (GO:0036065)2.99153235
128positive regulation of pseudopodium assembly (GO:0031274)2.97925674
129regulation of bile acid biosynthetic process (GO:0070857)2.97037284
130chondrocyte proliferation (GO:0035988)2.96632166
131regulation of systemic arterial blood pressure (GO:0003073)2.95489386
132striated muscle atrophy (GO:0014891)2.94342578
133primary alcohol catabolic process (GO:0034310)2.94098763
134regulation of viral entry into host cell (GO:0046596)2.93591868
135protein autoprocessing (GO:0016540)2.93187304
136positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.92328369
137NADH metabolic process (GO:0006734)2.91988853
138fat-soluble vitamin biosynthetic process (GO:0042362)2.91356117
139tight junction assembly (GO:0070830)2.91058722
140glandular epithelial cell differentiation (GO:0002067)2.90715851
141positive regulation of T cell differentiation in thymus (GO:0033089)2.89110603
142cell differentiation involved in embryonic placenta development (GO:0060706)2.87932520
143membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.87829600
144phosphatidylserine acyl-chain remodeling (GO:0036150)2.87637135
145positive regulation of cGMP biosynthetic process (GO:0030828)2.87429994
146primary alcohol metabolic process (GO:0034308)2.86810738
147left/right pattern formation (GO:0060972)2.81874935
148left/right axis specification (GO:0070986)2.81735322
149sodium ion homeostasis (GO:0055078)2.79326397
150glutathione metabolic process (GO:0006749)2.78763372
151water homeostasis (GO:0030104)2.73991406
152transcytosis (GO:0045056)2.72332004
153glutathione derivative metabolic process (GO:1901685)2.69691598
154glutathione derivative biosynthetic process (GO:1901687)2.69691598
155antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.68770125
156cellular response to reactive nitrogen species (GO:1902170)2.63216338
157hormone catabolic process (GO:0042447)2.63120307

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human7.01215689
2CDX2_20551321_ChIP-Seq_CACO-2_Human5.24057063
3SOX2_27498859_Chip-Seq_STOMACH_Mouse4.34136891
4SRY_22984422_ChIP-ChIP_TESTIS_Rat3.33441961
5CDX2_19796622_ChIP-Seq_MESCs_Mouse3.14236957
6GATA4_25053715_ChIP-Seq_YYC3_Human2.97074429
7SOX2_20726797_ChIP-Seq_SW620_Human2.89743302
8GATA6_25053715_ChIP-Seq_YYC3_Human2.88956641
9TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.81268137
10SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.76356348
11HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.56803460
12ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse2.56706074
13STAT6_21828071_ChIP-Seq_BEAS2B_Human2.54596395
14CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.48421261
15CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.45260494
16IRF8_22096565_ChIP-ChIP_GC-B_Human2.34791261
17PPARA_22158963_ChIP-Seq_LIVER_Mouse2.11185428
18BCL6_27268052_Chip-Seq_Bcells_Human2.06073354
19IKZF1_21737484_ChIP-ChIP_HCT116_Human2.06033453
20RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.99693763
21* KLF5_25053715_ChIP-Seq_YYC3_Human1.97907642
22STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.95826982
23BCOR_27268052_Chip-Seq_Bcells_Human1.93562106
24P68_20966046_ChIP-Seq_HELA_Human1.93036947
25RACK7_27058665_Chip-Seq_MCF-7_Human1.88421474
26ESR1_15608294_ChIP-ChIP_MCF-7_Human1.84914932
27NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.84785852
28RUNX1_27514584_Chip-Seq_MCF-7_Human1.76145080
29PPAR_26484153_Chip-Seq_NCI-H1993_Human1.75067332
30ESR1_21235772_ChIP-Seq_MCF-7_Human1.73955942
31SMC4_20622854_ChIP-Seq_HELA_Human1.72299562
32ESR2_21235772_ChIP-Seq_MCF-7_Human1.70254109
33FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.68690893
34ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.67764663
35TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.64684657
36FOXO3_23340844_ChIP-Seq_DLD1_Human1.62940534
37ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.59263645
38TRIM28_21343339_ChIP-Seq_HEK293_Human1.58125800
39RXR_22158963_ChIP-Seq_LIVER_Mouse1.57712968
40TCF4_18268006_ChIP-ChIP_LS174T_Human1.55048150
41VDR_22108803_ChIP-Seq_LS180_Human1.54836699
42KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.54795917
43RARG_19884340_ChIP-ChIP_MEFs_Mouse1.54667984
44* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.52523934
45ESR1_20079471_ChIP-ChIP_T-47D_Human1.51858229
46CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.49171359
47CTCF_20526341_ChIP-Seq_ESCs_Human1.48141580
48ELF1_20517297_ChIP-Seq_JURKAT_Human1.47069064
49PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.46380207
50* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.44808821
51LXR_22158963_ChIP-Seq_LIVER_Mouse1.44459766
52* BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.43872909
53NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.41710163
54MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.39546157
55SA1_27219007_Chip-Seq_Bcells_Human1.38136835
56PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.37984804
57PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.37103272
58SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.36832535
59AR_21909140_ChIP-Seq_LNCAP_Human1.35627547
60PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.35595907
61P300_27268052_Chip-Seq_Bcells_Human1.33425020
62IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.32203022
63TET1_21451524_ChIP-Seq_MESCs_Mouse1.32199364
64ATF3_27146783_Chip-Seq_COLON_Human1.31022338
65DROSHA_22980978_ChIP-Seq_HELA_Human1.29991054
66CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.28797745
67VDR_21846776_ChIP-Seq_THP-1_Human1.28243224
68SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.26637689
69SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.26637689
70EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.26635141
71GATA1_19941826_ChIP-Seq_K562_Human1.26439269
72* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.25776090
73RARB_24833708_ChIP-Seq_LIVER_Mouse1.24615490
74SA1_27219007_Chip-Seq_ERYTHROID_Human1.22303745
75SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.21706616
76FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.21700095
77YY1_22570637_ChIP-Seq_MALME-3M_Human1.21011504
78E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.20247043
79RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.18524169
80P53_21459846_ChIP-Seq_SAOS-2_Human1.15906041
81EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.15142727
82ERA_21632823_ChIP-Seq_H3396_Human1.14745890
83SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.11979411
84VDR_24763502_ChIP-Seq_THP-1_Human1.11782958
85TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.11111417
86CEBPB_22108803_ChIP-Seq_LS180_Human1.10317580
87P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.09685245
88GATA3_24758297_ChIP-Seq_MCF-7_Human1.08963447
89FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.08510322
90SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.07042334
91SOX2_21211035_ChIP-Seq_LN229_Human1.06933356
92EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.03123106
93JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.02862966
94LXR_22292898_ChIP-Seq_THP-1_Human1.02821906
95AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.02686502
96RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.00956916
97FOXM1_26456572_ChIP-Seq_MCF-7_Human0.99205642
98FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.98652664
99RAD21_21589869_ChIP-Seq_MESCs_Mouse0.98598693
100* EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.98519334
101NANOG_18692474_ChIP-Seq_MEFs_Mouse0.98110465
102OCT4_20526341_ChIP-Seq_ESCs_Human0.97211042
103EGR1_23403033_ChIP-Seq_LIVER_Mouse0.95499709
104OCT4_18692474_ChIP-Seq_MEFs_Mouse0.94620781
105PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.94589503
106* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.94569451
107CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.94348756
108CTCF_27219007_Chip-Seq_ERYTHROID_Human0.94260271
109GATA2_21666600_ChIP-Seq_HMVEC_Human0.94230192
110NANOG_20526341_ChIP-Seq_ESCs_Human0.93747455
111CREB1_26743006_Chip-Seq_LNCaP_Human0.93298737
112ETS1_21867929_ChIP-Seq_TH2_Mouse0.92968167
113EGR1_19032775_ChIP-ChIP_M12_Human0.92663500
114TDRD3_21172665_ChIP-Seq_MCF-7_Human0.92450755
115GATA1_26923725_Chip-Seq_HPCs_Mouse0.92263220
116TP53_22127205_ChIP-Seq_IMR90_Human0.91766405
117KDM2B_26808549_Chip-Seq_SUP-B15_Human0.91367571
118SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.91041328
119THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.90140172
120PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.89654453
121P63_26484246_Chip-Seq_KERATINOCYTES_Human0.89583708
122RARA_24833708_ChIP-Seq_LIVER_Mouse0.88890847
123TCF3_18692474_ChIP-Seq_MEFs_Mouse0.88213730
124PHF8_20622854_ChIP-Seq_HELA_Human0.87449962
125MYC_19915707_ChIP-ChIP_AK7_Human0.87441581
126ZNF263_19887448_ChIP-Seq_K562_Human0.87350305
127JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.86711620
128TP63_22573176_ChIP-Seq_HFKS_Human0.85758314
129CTCF_27219007_Chip-Seq_Bcells_Human0.85657740
130GATA2_19941826_ChIP-Seq_K562_Human0.85589830
131* HNF4A_19822575_ChIP-Seq_HepG2_Human0.85451073
132FOXA1_25552417_ChIP-Seq_VCAP_Human0.85133868
133STAT1_20625510_ChIP-Seq_HELA_Human0.84207002
134SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.83850437
135CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.83173582
136CDX2_22108803_ChIP-Seq_LS180_Human0.82776785
137E2F1_20622854_ChIP-Seq_HELA_Human0.81531448
138GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.79073297
139AHR_22903824_ChIP-Seq_MCF-7_Human0.78057520

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002822_catalepsy5.02129748
2MP0005377_hearing/vestibular/ear_phenot4.70900353
3MP0003878_abnormal_ear_physiology4.70900353
4MP0010234_abnormal_vibrissa_follicle4.62827477
5MP0003283_abnormal_digestive_organ4.48400386
6MP0003136_yellow_coat_color3.87232091
7MP0003866_abnormal_defecation3.84229850
8MP0000462_abnormal_digestive_system3.82244288
9MP0001873_stomach_inflammation3.58456239
10MP0004264_abnormal_extraembryonic_tissu3.55623945
11MP0005409_darkened_coat_color3.37115902
12MP0001666_abnormal_nutrient_absorption3.28949475
13MP0001663_abnormal_digestive_system3.14636478
14MP0005174_abnormal_tail_pigmentation3.12367858
15MP0005381_digestive/alimentary_phenotyp3.07419888
16MP0008004_abnormal_stomach_pH2.99574537
17MP0000015_abnormal_ear_pigmentation2.97047285
18MP0000490_abnormal_crypts_of2.94757792
19MP0010155_abnormal_intestine_physiology2.92643193
20MP0008875_abnormal_xenobiotic_pharmacok2.89888889
21MP0005360_urolithiasis2.76996290
22MP0005167_abnormal_blood-brain_barrier2.67911256
23MP0010352_gastrointestinal_tract_polyps2.56505778
24MP0003315_abnormal_perineum_morphology2.51088014
25MP0001664_abnormal_digestion2.48709381
26MP0005171_absent_coat_pigmentation2.42477310
27MP0000477_abnormal_intestine_morphology2.42384209
28MP0001188_hyperpigmentation2.39156208
29MP0004381_abnormal_hair_follicle2.27441981
30MP0005085_abnormal_gallbladder_physiolo2.19223429
31MP0003806_abnormal_nucleotide_metabolis2.13863997
32MP0000537_abnormal_urethra_morphology2.12589282
33MP0000372_irregular_coat_pigmentation2.05734411
34MP0004043_abnormal_pH_regulation1.97671206
35MP0005075_abnormal_melanosome_morpholog1.96639165
36MP0005083_abnormal_biliary_tract1.79332804
37MP0003183_abnormal_peptide_metabolism1.78333779
38MP0005408_hypopigmentation1.72110185
39MP0002796_impaired_skin_barrier1.70397423
40MP0001765_abnormal_ion_homeostasis1.68640481
41MP0003191_abnormal_cellular_cholesterol1.68237408
42MP0002876_abnormal_thyroid_physiology1.67100617
43MP0000470_abnormal_stomach_morphology1.65133728
44MP0003300_gastrointestinal_ulcer1.61592805
45MP0001849_ear_inflammation1.57331195
46MP0005365_abnormal_bile_salt1.54494182
47MP0000538_abnormal_urinary_bladder1.52710616
48MP0009379_abnormal_foot_pigmentation1.46373668
49MP0009840_abnormal_foam_cell1.45451052
50MP0001986_abnormal_taste_sensitivity1.44786675
51MP0003941_abnormal_skin_development1.44106845
52MP0003868_abnormal_feces_composition1.40974449
53MP0003705_abnormal_hypodermis_morpholog1.40746164
54MP0002277_abnormal_respiratory_mucosa1.39202959
55MP0000566_synostosis1.37775084
56MP0003693_abnormal_embryo_hatching1.36244902
57MP0000371_diluted_coat_color1.28022123
58MP0005636_abnormal_mineral_homeostasis1.24853689
59MP0002653_abnormal_ependyma_morphology1.23874402
60MP0002095_abnormal_skin_pigmentation1.22300742
61MP0004019_abnormal_vitamin_homeostasis1.21732881
62MP0005166_decreased_susceptibility_to1.20462265
63MP0003879_abnormal_hair_cell1.19461418
64MP0005410_abnormal_fertilization1.19066864
65MP0005332_abnormal_amino_acid1.18450240
66MP0002139_abnormal_hepatobiliary_system1.18100158
67MP0006054_spinal_hemorrhage1.14282168
68MP0000467_abnormal_esophagus_morphology1.12360993
69MP0009643_abnormal_urine_homeostasis1.08200423
70MP0000013_abnormal_adipose_tissue1.05484654
71MP0000383_abnormal_hair_follicle1.05064768
72MP0009780_abnormal_chondrocyte_physiolo1.03490457
73MP0002249_abnormal_larynx_morphology1.02628546
74MP0005670_abnormal_white_adipose1.02622810
75MP0009384_cardiac_valve_regurgitation1.02517786
76MP0005310_abnormal_salivary_gland0.98989947
77MP0005501_abnormal_skin_physiology0.97815686
78MP0000681_abnormal_thyroid_gland0.95114479
79MP0010678_abnormal_skin_adnexa0.93050825
80MP0003252_abnormal_bile_duct0.89267082
81MP0003718_maternal_effect0.87527989
82MP0004782_abnormal_surfactant_physiolog0.86728458
83MP0004947_skin_inflammation0.83380017
84MP0001485_abnormal_pinna_reflex0.82905712
85MP0004484_altered_response_of0.82816708
86MP0002060_abnormal_skin_morphology0.82730154
87MP0003453_abnormal_keratinocyte_physiol0.82154973
88MP0004147_increased_porphyrin_level0.81526145
89MP0005257_abnormal_intraocular_pressure0.81284478
90MP0005165_increased_susceptibility_to0.81059102
91MP0010329_abnormal_lipoprotein_level0.80877348
92MP0000678_abnormal_parathyroid_gland0.80491231
93MP0001764_abnormal_homeostasis0.79496658
94MP0002132_abnormal_respiratory_system0.77197344
95MP0004185_abnormal_adipocyte_glucose0.75953816
96MP0003303_peritoneal_inflammation0.75647104
97MP0001324_abnormal_eye_pigmentation0.75060322
98MP0000465_gastrointestinal_hemorrhage0.72607314
99MP0000613_abnormal_salivary_gland0.71447486
100MP0001216_abnormal_epidermal_layer0.70170877
101MP0000230_abnormal_systemic_arterial0.69325011
102MP0002138_abnormal_hepatobiliary_system0.68750340
103MP0002098_abnormal_vibrissa_morphology0.68651269
104MP0003045_fibrosis0.67685602
105MP0002102_abnormal_ear_morphology0.67497240
106MP0000516_abnormal_urinary_system0.65733333
107MP0005367_renal/urinary_system_phenotyp0.65733333
108MP0005025_abnormal_response_to0.65021249
109MP0008872_abnormal_physiological_respon0.64083278
110MP0000762_abnormal_tongue_morphology0.63734341
111MP0005395_other_phenotype0.63400427
112MP0002234_abnormal_pharynx_morphology0.61032857
113MP0008873_increased_physiological_sensi0.58621258
114MP0002136_abnormal_kidney_physiology0.58562566
115MP0001502_abnormal_circadian_rhythm0.56321710
116MP0001790_abnormal_immune_system0.55776640
117MP0005387_immune_system_phenotype0.55776640
118MP0004858_abnormal_nervous_system0.51144417
119MP0010771_integument_phenotype0.47763710
120MP0000609_abnormal_liver_physiology0.47401635
121MP0002166_altered_tumor_susceptibility0.45756841
122MP0002896_abnormal_bone_mineralization0.44709460
123MP0005266_abnormal_metabolism0.43714603
124MP0002118_abnormal_lipid_homeostasis0.42538814
125MP0001756_abnormal_urination0.42372306
126MP0001440_abnormal_grooming_behavior0.42281570
127MP0001845_abnormal_inflammatory_respons0.41574622
128MP0001529_abnormal_vocalization0.40001468
129MP0010030_abnormal_orbit_morphology0.38350373
130MP0009785_altered_susceptibility_to0.38067087
131MP0003385_abnormal_body_wall0.37513695
132MP0002160_abnormal_reproductive_system0.36937661
133MP0004957_abnormal_blastocyst_morpholog0.36240115
134MP0003075_altered_response_to0.35942883
135MP0005084_abnormal_gallbladder_morpholo0.35908108
136MP0002006_tumorigenesis0.35535148
137MP0003950_abnormal_plasma_membrane0.35487119
138MP0009053_abnormal_anal_canal0.35289545
139MP0005319_abnormal_enzyme/_coenzyme0.34801617
140MP0005666_abnormal_adipose_tissue0.33740754
141MP0005584_abnormal_enzyme/coenzyme_acti0.32405860

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)7.76686699
2Abnormal respiratory epithelium morphology (HP:0012253)7.01835669
3Abnormal respiratory motile cilium morphology (HP:0005938)7.01835669
4Dynein arm defect of respiratory motile cilia (HP:0012255)6.73152524
5Absent/shortened dynein arms (HP:0200106)6.73152524
6Abnormal respiratory motile cilium physiology (HP:0012261)6.63411803
7Abnormal ciliary motility (HP:0012262)6.40633156
8Chronic bronchitis (HP:0004469)6.15156552
9Rhinitis (HP:0012384)6.12852085
10Abnormality of the 1st metacarpal (HP:0010009)5.95425489
11Ileus (HP:0002595)5.73817066
12Right ventricular cardiomyopathy (HP:0011663)5.64070123
13Hyperactive renin-angiotensin system (HP:0000841)5.59806526
14Flat acetabular roof (HP:0003180)5.36180432
15Pustule (HP:0200039)5.29052077
16Bronchiectasis (HP:0002110)5.16718695
17Nasal polyposis (HP:0100582)5.14393328
18Metabolic alkalosis (HP:0200114)5.06089801
19Abnormality of the nasal mucosa (HP:0000433)4.83873739
20Cupped ribs (HP:0000887)4.56590342
21Abnormal tarsal ossification (HP:0008369)4.43174178
22Abnormality of the distal phalanx of the thumb (HP:0009617)4.38448744
23Short phalanx of the thumb (HP:0009660)4.28984341
24Abnormality of glutamine family amino acid metabolism (HP:0010902)4.22085581
25Abdominal distention (HP:0003270)4.17468925
26Abnormality of carpal bone ossification (HP:0006257)4.06455394
27Male infertility (HP:0003251)4.01841129
28Abnormality of chloride homeostasis (HP:0011422)3.92260764
29Congenital sensorineural hearing impairment (HP:0008527)3.73226210
30Abnormality of renin-angiotensin system (HP:0000847)3.58678162
31Symphalangism affecting the phalanges of the hand (HP:0009773)3.55879634
32Ureteral stenosis (HP:0000071)3.50032225
33Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)3.46679022
34Bronchitis (HP:0012387)3.45495392
35Septate vagina (HP:0001153)3.40771643
36Abnormality of the phalanges of the hallux (HP:0010057)3.31725638
37Abnormality of the 2nd finger (HP:0004100)3.31603103
38Alopecia of scalp (HP:0002293)3.27560738
39Breech presentation (HP:0001623)3.25458886
40Ureteral obstruction (HP:0006000)3.24009646
41Short 1st metacarpal (HP:0010034)3.23169774
42Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)3.23169774
43Hemorrhage of the eye (HP:0011885)3.22631312
44Decreased circulating renin level (HP:0003351)3.21700246
45Abnormality of the proximal phalanges of the hand (HP:0009834)3.20645331
46Infertility (HP:0000789)3.18643797
47Abnormal ossification of hand bones (HP:0005921)3.14635849
48Milia (HP:0001056)3.11072448
49Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)3.10552817
50Chronic sinusitis (HP:0011109)3.10489430
51Gastrointestinal dysmotility (HP:0002579)3.10414771
52Abnormal foot bone ossification (HP:0010675)3.09856365
53Abnormal hand bone ossification (HP:0010660)3.06983926
54Malnutrition (HP:0004395)3.03629832
55Hyperkalemia (HP:0002153)3.03335469
56Flattened epiphyses (HP:0003071)2.96989167
57Fragile nails (HP:0001808)2.87535864
58Congenital stationary night blindness (HP:0007642)2.82761820
59Hydroxyprolinuria (HP:0003080)2.81712939
60Abnormality of proline metabolism (HP:0010907)2.81712939
61Recurrent sinusitis (HP:0011108)2.76814156
62Ocular albinism (HP:0001107)2.76011700
63Chronic diarrhea (HP:0002028)2.67236136
64Abnormality of monocarboxylic acid metabolism (HP:0010996)2.65038518
65Woolly hair (HP:0002224)2.64736511
66Ventricular fibrillation (HP:0001663)2.61710973
67Mildly elevated creatine phosphokinase (HP:0008180)2.61376813
68Hyperaldosteronism (HP:0000859)2.61334408
69Biliary tract neoplasm (HP:0100574)2.60151749
70Hyponatremia (HP:0002902)2.59483802
71Syncope (HP:0001279)2.59370001
72Abnormality of the middle phalanges of the toes (HP:0010183)2.59354424
73Palpitations (HP:0001962)2.58955767
74Cheilitis (HP:0100825)2.57435310
75Micronodular cirrhosis (HP:0001413)2.57237503
76Decreased central vision (HP:0007663)2.57025353
77Onycholysis (HP:0001806)2.55899102
78Neonatal short-limb short stature (HP:0008921)2.55626462
79Atelectasis (HP:0100750)2.54079819
80Short hallux (HP:0010109)2.53428713
81Short middle phalanx of finger (HP:0005819)2.49552977
82Aplasia/hypoplasia of the femur (HP:0005613)2.49440454
83Abnormality of small intestinal villus morphology (HP:0011472)2.48013264
84Villous atrophy (HP:0011473)2.48013264
85Atrophic scars (HP:0001075)2.46906915
86Recurrent otitis media (HP:0000403)2.45323226
87Chronic otitis media (HP:0000389)2.45064272
88Cone-rod dystrophy (HP:0000548)2.44927993
89Abnormal biliary tract morphology (HP:0012440)2.44648613
90Alkalosis (HP:0001948)2.43800116
91Tracheal stenosis (HP:0002777)2.42753220
92Dehydration (HP:0001944)2.38651013
93Renal salt wasting (HP:0000127)2.38251272
94Iris hypopigmentation (HP:0007730)2.37680125
95Plantar hyperkeratosis (HP:0007556)2.34923066
96Fat malabsorption (HP:0002630)2.32883128
97Abnormality of the vitamin B12 metabolism (HP:0004341)2.30373434
98Fragile skin (HP:0001030)2.29208493
99Aplasia/Hypoplasia of the hallux (HP:0008362)2.28665658
100Intrahepatic cholestasis (HP:0001406)2.26815674
101Absent phalangeal crease (HP:0006109)2.22968281
102Abnormality of the gastric mucosa (HP:0004295)2.22789421
103Bundle branch block (HP:0011710)2.19597273
104Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)2.17431717
105Aplasia/Hypoplasia of the macula (HP:0008059)2.16391009
106Conjugated hyperbilirubinemia (HP:0002908)2.15973796
107Hyperparathyroidism (HP:0000843)2.14924605
108Widely patent fontanelles and sutures (HP:0004492)2.12656750
109Abnormal cartilage morphology (HP:0002763)2.12130508
110Thin bony cortex (HP:0002753)2.11918907
111Tubular atrophy (HP:0000092)2.11724122
112Occipital encephalocele (HP:0002085)2.11507132
113Abnormality of vitamin B metabolism (HP:0004340)2.11152561
114Enlarged epiphyses (HP:0010580)2.11003496
115Pigmentary retinal degeneration (HP:0001146)2.10748191
116Petechiae (HP:0000967)2.09514215
117Vertebral clefting (HP:0008428)2.09156532
118Pili torti (HP:0003777)2.08116215
119Acanthocytosis (HP:0001927)2.05028277
120Spinal cord compression (HP:0002176)2.04160758
121Microretrognathia (HP:0000308)2.01520320
122Coxa vara (HP:0002812)2.00404560
123Hoarse voice (HP:0001609)2.00371016
124Abnormality of the costochondral junction (HP:0000919)2.00139760
125Progressive sensorineural hearing impairment (HP:0000408)1.99373824
126Abnormality of potassium homeostasis (HP:0011042)1.98684767
127Abnormal hair laboratory examination (HP:0003328)1.98299594
128Aplasia/Hypoplasia affecting the retina (HP:0008061)1.98069771
129Abnormality of vitamin metabolism (HP:0100508)1.96250577
130Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.95390880
131Prolonged QT interval (HP:0001657)1.93553607
132Tibial bowing (HP:0002982)1.93085999
133Hypoplasia of dental enamel (HP:0006297)1.92942855
134Systemic lupus erythematosus (HP:0002725)1.92027665
135Popliteal pterygium (HP:0009756)1.89906363
136Polycythemia (HP:0001901)1.89692951
137Sensorimotor neuropathy (HP:0007141)1.88979501
138Flat capital femoral epiphysis (HP:0003370)1.88960274
139Hypokalemia (HP:0002900)1.88864359
140Short femoral neck (HP:0100864)1.88798920
141Abnormal finger flexion creases (HP:0006143)1.86077599
142Genu varum (HP:0002970)1.83836892
143Abnormality of dicarboxylic acid metabolism (HP:0010995)1.83777070
144Dicarboxylic aciduria (HP:0003215)1.83777070
145Abnormality of sodium homeostasis (HP:0010931)1.80882094
146Cystic liver disease (HP:0006706)1.78978787
147Dyschromatopsia (HP:0007641)1.75224933
148Lip pit (HP:0100267)1.74580779
149Tubulointerstitial nephritis (HP:0001970)1.74579878
150Hypotension (HP:0002615)1.72065632
151Akinesia (HP:0002304)1.68047801
152Abnormal albumin level (HP:0012116)1.67436022
153Hypoalbuminemia (HP:0003073)1.67436022
154Delayed epiphyseal ossification (HP:0002663)1.63454963
155Steatorrhea (HP:0002570)1.60325562
156Recurrent bronchitis (HP:0002837)1.60103344
157White forelock (HP:0002211)1.59963789
158Adrenal overactivity (HP:0002717)1.59149073
159Abnormality of midbrain morphology (HP:0002418)1.58054211
160Molar tooth sign on MRI (HP:0002419)1.58054211
161Stridor (HP:0010307)1.57873038
162Patchy hypopigmentation of hair (HP:0011365)1.57235194
163Confusion (HP:0001289)1.57120162
164Aplasia/Hypoplasia of the fovea (HP:0008060)1.54939912
165Hypoplasia of the fovea (HP:0007750)1.54939912
166Aplasia of the musculature (HP:0100854)1.52096859
167Protuberant abdomen (HP:0001538)1.51579318
168Nephronophthisis (HP:0000090)1.47533358
169Wide cranial sutures (HP:0010537)1.46957605
170Rib fusion (HP:0000902)1.45364416

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST1R6.09103022
2MAPK155.53779132
3PIK3CA4.85432067
4ACVR1B4.36263002
5LMTK24.11948483
6FRK4.07472199
7MST43.88917022
8MAP2K23.53510670
9TESK13.07227205
10PRKG23.05925530
11DDR22.45264036
12TBK12.40484763
13MYLK2.23089309
14EPHB22.15967745
15EPHA22.10063072
16NME12.08978335
17GRK61.99135585
18MAPKAPK31.92208809
19TAOK11.84211176
20MET1.84209029
21MAP3K21.75836551
22MATK1.71368606
23IKBKE1.38891675
24PDPK11.33546770
25PTK61.33405444
26MUSK1.27957969
27CAMK2D1.16777990
28WNK41.16120848
29PRKCI1.15820449
30ICK1.15262235
31MAP2K11.15113827
32PIM21.14826789
33TTK1.13809519
34RIPK11.12556922
35MAP3K81.06373530
36DMPK1.05957205
37OXSR11.05643870
38TLK11.03971634
39ERBB41.02949570
40PDK21.00549367
41PAK41.00546823
42KSR20.97760099
43LIMK10.95581441
44SIK10.95401069
45TAOK30.94050842
46PTK20.93687735
47PDK10.93111242
48PTK2B0.91248311
49NEK60.90662889
50BRAF0.89839922
51CSK0.88375792
52STK240.88134875
53CDC42BPA0.87314307
54PDK40.85487399
55PDK30.85487399
56ARAF0.85407195
57BMPR1B0.84345515
58FGFR40.84161877
59RIPK40.83941699
60SMG10.82972713
61MAP3K120.82824071
62MAP2K60.81214818
63MAP4K10.80848368
64ADRBK20.77510878
65TYK20.77452662
66ERBB20.76409336
67MAP3K110.75801130
68STK100.73288533
69STK160.73180724
70MAP3K10.72363651
71STK390.70121653
72ERN10.68700655
73FER0.65854498
74CAMK2G0.63575444
75TESK20.63238371
76MAP3K100.60206383
77AURKB0.59920758
78ZAP700.59789342
79PRKD20.58666048
80CAMK2B0.57985208
81RPS6KB20.57565958
82TYRO30.57515901
83EPHB10.56785147
84ADRBK10.55679768
85EPHA30.50274315
86PBK0.49508325
87PAK10.49491516
88FGFR30.49315211
89PRKCA0.47809373
90MAP3K60.47181254
91CDK90.46438623
92RPS6KA20.43868967
93LATS10.42284844
94FGR0.41343778
95IRAK10.41062360
96TNK20.40424392
97CDK120.39877242
98MAPKAPK50.39448554
99DAPK30.39447152
100PAK30.39220567
101GRK10.38673615
102PRKAA20.38516638
103NUAK10.38429652
104CHUK0.38229540
105KIT0.38058792
106IKBKB0.37851274
107ROCK10.36975326
108MAPK110.36821107
109SRC0.33933749
110BMX0.33738271
111MAP3K30.32991837
112TRPM70.29940905
113EEF2K0.28563277
114LRRK20.27185985
115MARK20.26254596
116PDGFRA0.26142832
117TGFBR20.25920721
118BMPR20.24801378
119PRKCD0.24792536
120NEK10.24526308
121PRKCH0.24149106
122ABL20.24008729
123PAK20.23157644
124IGF1R0.23110972
125PRKAA10.23064460
126PRKD30.23000586
127PKN20.22867475
128CSNK1A10.22532482
129PDGFRB0.21660653
130KDR0.21517515
131RPS6KA10.21034622
132MAP3K70.20556675
133MAPKAPK20.20336149
134PRKCQ0.19792163
135HIPK20.19562394
136PIK3CG0.19561104
137PRKG10.18991884
138PRKD10.18780637
139AKT20.18693143
140WNK10.18552289
141DYRK1B0.18526920
142PRKACG0.18232443
143BLK0.18046882
144STK380.17281886
145TRIB30.17261665

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur metabolism_Homo sapiens_hsa009207.43474181
2Mineral absorption_Homo sapiens_hsa049784.10575194
3Butirosin and neomycin biosynthesis_Homo sapiens_hsa005243.53010106
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.11304673
5Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.88538256
6Fat digestion and absorption_Homo sapiens_hsa049752.68194247
7Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.55844233
8Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.51385734
9Fructose and mannose metabolism_Homo sapiens_hsa000512.20098111
10Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005202.10726611
11Pentose and glucuronate interconversions_Homo sapiens_hsa000402.02359965
12Sulfur relay system_Homo sapiens_hsa041221.95696591
13Bile secretion_Homo sapiens_hsa049761.91676715
14Histidine metabolism_Homo sapiens_hsa003401.89462682
15Tyrosine metabolism_Homo sapiens_hsa003501.89455881
16Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.84979102
17Arginine biosynthesis_Homo sapiens_hsa002201.73933586
18Butanoate metabolism_Homo sapiens_hsa006501.67276159
19Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.65647071
20Oxidative phosphorylation_Homo sapiens_hsa001901.61860567
21Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.59080535
22Galactose metabolism_Homo sapiens_hsa000521.51784635
23Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.50751676
24alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.46598016
25Chemical carcinogenesis_Homo sapiens_hsa052041.45272232
26Maturity onset diabetes of the young_Homo sapiens_hsa049501.43440510
27Pancreatic secretion_Homo sapiens_hsa049721.39661506
28Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.36741777
29Linoleic acid metabolism_Homo sapiens_hsa005911.30879491
30Tight junction_Homo sapiens_hsa045301.25794515
31Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.24825876
32Glutathione metabolism_Homo sapiens_hsa004801.23147307
33Parkinsons disease_Homo sapiens_hsa050121.20435136
34Starch and sucrose metabolism_Homo sapiens_hsa005001.16668087
35Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.16224070
36Asthma_Homo sapiens_hsa053101.11850431
37Alzheimers disease_Homo sapiens_hsa050101.09887434
38Steroid hormone biosynthesis_Homo sapiens_hsa001401.07693274
39Glycerolipid metabolism_Homo sapiens_hsa005611.06747677
40Tryptophan metabolism_Homo sapiens_hsa003801.04713962
41Pentose phosphate pathway_Homo sapiens_hsa000301.03254621
42Renin-angiotensin system_Homo sapiens_hsa046141.01863822
43Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.97093791
44Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.96992682
45Cardiac muscle contraction_Homo sapiens_hsa042600.96370537
46Gastric acid secretion_Homo sapiens_hsa049710.95544091
47Fatty acid degradation_Homo sapiens_hsa000710.93941369
48Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.92633118
49Protein digestion and absorption_Homo sapiens_hsa049740.89622142
50Salivary secretion_Homo sapiens_hsa049700.83263501
51PPAR signaling pathway_Homo sapiens_hsa033200.81403178
52Allograft rejection_Homo sapiens_hsa053300.80840080
53Vitamin digestion and absorption_Homo sapiens_hsa049770.80069754
54ABC transporters_Homo sapiens_hsa020100.79923531
55Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.79888150
56Folate biosynthesis_Homo sapiens_hsa007900.79701945
572-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.74779251
58Carbohydrate digestion and absorption_Homo sapiens_hsa049730.74210938
59Steroid biosynthesis_Homo sapiens_hsa001000.74100270
60Autoimmune thyroid disease_Homo sapiens_hsa053200.73530827
61Peroxisome_Homo sapiens_hsa041460.73472525
62Huntingtons disease_Homo sapiens_hsa050160.72546505
63Glycosaminoglycan degradation_Homo sapiens_hsa005310.72112027
64Salmonella infection_Homo sapiens_hsa051320.70511860
65Graft-versus-host disease_Homo sapiens_hsa053320.69203341
66Retinol metabolism_Homo sapiens_hsa008300.63064318
67Caffeine metabolism_Homo sapiens_hsa002320.62888235
68Thyroid hormone synthesis_Homo sapiens_hsa049180.62141673
69Glycerophospholipid metabolism_Homo sapiens_hsa005640.61825792
70Thyroid cancer_Homo sapiens_hsa052160.61690314
71Pyruvate metabolism_Homo sapiens_hsa006200.61482050
72Leukocyte transendothelial migration_Homo sapiens_hsa046700.60370811
73Arachidonic acid metabolism_Homo sapiens_hsa005900.59495653
74Sphingolipid metabolism_Homo sapiens_hsa006000.58925167
75Carbon metabolism_Homo sapiens_hsa012000.58923965
76Hepatitis C_Homo sapiens_hsa051600.57676107
77Primary bile acid biosynthesis_Homo sapiens_hsa001200.56683598
78Drug metabolism - other enzymes_Homo sapiens_hsa009830.55538704
79Bladder cancer_Homo sapiens_hsa052190.55051035
80Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.54886402
81Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.54360306
82Ether lipid metabolism_Homo sapiens_hsa005650.52606932
83Type I diabetes mellitus_Homo sapiens_hsa049400.48867646
84Taste transduction_Homo sapiens_hsa047420.47045943
85Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.46031453
86Metabolic pathways_Homo sapiens_hsa011000.45810243
87Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.44832521
88Phenylalanine metabolism_Homo sapiens_hsa003600.44604687
89Insulin resistance_Homo sapiens_hsa049310.44007142
90Notch signaling pathway_Homo sapiens_hsa043300.42353865
91African trypanosomiasis_Homo sapiens_hsa051430.42225696
92Vibrio cholerae infection_Homo sapiens_hsa051100.40010306
93Staphylococcus aureus infection_Homo sapiens_hsa051500.39875443
94Adherens junction_Homo sapiens_hsa045200.38645654
95Intestinal immune network for IgA production_Homo sapiens_hsa046720.38400854
96Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.37773601
97Ovarian steroidogenesis_Homo sapiens_hsa049130.36715349
98Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.35436163
99Arginine and proline metabolism_Homo sapiens_hsa003300.35359047
100Pertussis_Homo sapiens_hsa051330.32097330
101Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.31785655
102Lysosome_Homo sapiens_hsa041420.30769552
103beta-Alanine metabolism_Homo sapiens_hsa004100.30456506
104Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.29596686
105Antigen processing and presentation_Homo sapiens_hsa046120.27304694
106Influenza A_Homo sapiens_hsa051640.25969993
107Propanoate metabolism_Homo sapiens_hsa006400.25362494
108Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.22679070
109Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.22547872
110N-Glycan biosynthesis_Homo sapiens_hsa005100.19344727
111RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.19292747
112Other glycan degradation_Homo sapiens_hsa005110.18325237
113Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.16718588
114Adipocytokine signaling pathway_Homo sapiens_hsa049200.16646476
115Cysteine and methionine metabolism_Homo sapiens_hsa002700.16416819
116Hematopoietic cell lineage_Homo sapiens_hsa046400.16243951
117Renin secretion_Homo sapiens_hsa049240.14649242
118Phosphatidylinositol signaling system_Homo sapiens_hsa040700.12757372
119Inositol phosphate metabolism_Homo sapiens_hsa005620.12176253
120Dorso-ventral axis formation_Homo sapiens_hsa043200.12026733
121Vascular smooth muscle contraction_Homo sapiens_hsa042700.11801787
122Cyanoamino acid metabolism_Homo sapiens_hsa004600.11781973
123Nitrogen metabolism_Homo sapiens_hsa009100.11646321
124Gap junction_Homo sapiens_hsa045400.09994586
125Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.09733755
126Choline metabolism in cancer_Homo sapiens_hsa052310.09570561
127Fatty acid biosynthesis_Homo sapiens_hsa000610.09561941
128Fatty acid metabolism_Homo sapiens_hsa012120.08484292
129Selenocompound metabolism_Homo sapiens_hsa004500.06654592
130Insulin secretion_Homo sapiens_hsa049110.05957347
131VEGF signaling pathway_Homo sapiens_hsa043700.05017094

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »