Rank | Gene Set | Z-score |
---|---|---|
1 | mitotic chromosome condensation (GO:0007076) | 6.55032146 |
2 | mitotic sister chromatid segregation (GO:0000070) | 6.35184708 |
3 | sister chromatid segregation (GO:0000819) | 6.11452635 |
4 | nuclear pore complex assembly (GO:0051292) | 6.02889337 |
5 | protein localization to chromosome, centromeric region (GO:0071459) | 5.92672013 |
6 | mitotic metaphase plate congression (GO:0007080) | 5.81979909 |
7 | protein localization to kinetochore (GO:0034501) | 5.77874508 |
8 | DNA unwinding involved in DNA replication (GO:0006268) | 5.71428562 |
9 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 5.46806709 |
10 | nuclear pore organization (GO:0006999) | 5.36930144 |
11 | metaphase plate congression (GO:0051310) | 5.10544320 |
12 | DNA topological change (GO:0006265) | 5.05324014 |
13 | regulation of mitotic spindle organization (GO:0060236) | 4.88210006 |
14 | kinetochore organization (GO:0051383) | 4.78832112 |
15 | regulation of spindle organization (GO:0090224) | 4.78159607 |
16 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.68042768 |
17 | DNA strand elongation (GO:0022616) | 4.55570784 |
18 | pore complex assembly (GO:0046931) | 4.50868288 |
19 | mitotic nuclear envelope disassembly (GO:0007077) | 4.48314740 |
20 | establishment of chromosome localization (GO:0051303) | 4.48128474 |
21 | mitotic sister chromatid cohesion (GO:0007064) | 4.42176708 |
22 | positive regulation of chromosome segregation (GO:0051984) | 4.32864457 |
23 | regulation of chromosome segregation (GO:0051983) | 4.32614335 |
24 | chromosome condensation (GO:0030261) | 4.32076221 |
25 | CENP-A containing nucleosome assembly (GO:0034080) | 4.31377219 |
26 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.30280803 |
27 | negative regulation of chromosome segregation (GO:0051985) | 4.21331254 |
28 | membrane disassembly (GO:0030397) | 4.20464406 |
29 | nuclear envelope disassembly (GO:0051081) | 4.20464406 |
30 | spindle checkpoint (GO:0031577) | 4.17127297 |
31 | DNA replication checkpoint (GO:0000076) | 4.10824519 |
32 | DNA ligation (GO:0006266) | 4.10449790 |
33 | establishment of integrated proviral latency (GO:0075713) | 4.10124703 |
34 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 4.09423721 |
35 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 4.09423721 |
36 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 4.09423721 |
37 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 4.09423721 |
38 | negative regulation of sister chromatid segregation (GO:0033046) | 4.09423721 |
39 | chromatin remodeling at centromere (GO:0031055) | 4.07966404 |
40 | mitotic spindle checkpoint (GO:0071174) | 4.07517073 |
41 | chromosome segregation (GO:0007059) | 4.07299797 |
42 | mitotic spindle assembly checkpoint (GO:0007094) | 4.02609670 |
43 | meiotic chromosome segregation (GO:0045132) | 4.02434020 |
44 | protein localization to chromosome (GO:0034502) | 3.99933388 |
45 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.98344082 |
46 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.98344082 |
47 | spindle assembly checkpoint (GO:0071173) | 3.96580721 |
48 | DNA replication initiation (GO:0006270) | 3.93915791 |
49 | regulation of sister chromatid segregation (GO:0033045) | 3.93689561 |
50 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.93689561 |
51 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.93689561 |
52 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.93530945 |
53 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.93530945 |
54 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.93530945 |
55 | kinetochore assembly (GO:0051382) | 3.92071572 |
56 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.84281951 |
57 | mitotic recombination (GO:0006312) | 3.82547185 |
58 | formation of translation preinitiation complex (GO:0001731) | 3.81056772 |
59 | regulation of translational fidelity (GO:0006450) | 3.79750526 |
60 | DNA packaging (GO:0006323) | 3.78991517 |
61 | telomere maintenance via recombination (GO:0000722) | 3.75810186 |
62 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.65800342 |
63 | DNA replication-independent nucleosome organization (GO:0034724) | 3.65800342 |
64 | histone exchange (GO:0043486) | 3.47378242 |
65 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.46953883 |
66 | regulation of centriole replication (GO:0046599) | 3.46670940 |
67 | regulation of sister chromatid cohesion (GO:0007063) | 3.45382714 |
68 | regulation of centrosome cycle (GO:0046605) | 3.45143623 |
69 | DNA conformation change (GO:0071103) | 3.39494801 |
70 | DNA synthesis involved in DNA repair (GO:0000731) | 3.38597855 |
71 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.33920461 |
72 | microtubule depolymerization (GO:0007019) | 3.31148911 |
73 | nuclear envelope organization (GO:0006998) | 3.28697856 |
74 | DNA duplex unwinding (GO:0032508) | 3.24350830 |
75 | regulation of RNA export from nucleus (GO:0046831) | 3.22911340 |
76 | negative regulation of mitosis (GO:0045839) | 3.22359503 |
77 | regulation of DNA endoreduplication (GO:0032875) | 3.17655568 |
78 | IMP biosynthetic process (GO:0006188) | 3.16341403 |
79 | DNA geometric change (GO:0032392) | 3.14591979 |
80 | ATP-dependent chromatin remodeling (GO:0043044) | 3.14038902 |
81 | chromatin assembly or disassembly (GO:0006333) | 3.13274131 |
82 | purine nucleobase biosynthetic process (GO:0009113) | 3.12450947 |
83 | protein complex localization (GO:0031503) | 3.09724723 |
84 | establishment of viral latency (GO:0019043) | 3.09626599 |
85 | mitotic G2/M transition checkpoint (GO:0044818) | 3.09038711 |
86 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.08174962 |
87 | mitotic cell cycle (GO:0000278) | 3.07473072 |
88 | telomere maintenance via telomere lengthening (GO:0010833) | 3.01602991 |
89 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435) | 3.00064655 |
90 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.99292310 |
91 | chromosome organization (GO:0051276) | 2.97451617 |
92 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.97212873 |
93 | resolution of meiotic recombination intermediates (GO:0000712) | 2.97202963 |
94 | regulation of histone H3-K9 methylation (GO:0051570) | 2.96777418 |
95 | synapsis (GO:0007129) | 2.95838779 |
96 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.95660827 |
97 | non-recombinational repair (GO:0000726) | 2.95660827 |
98 | nucleobase biosynthetic process (GO:0046112) | 2.95632741 |
99 | IMP metabolic process (GO:0046040) | 2.91788025 |
100 | ribosome assembly (GO:0042255) | 2.88185088 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 9.10624664 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 6.99840851 |
3 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.46162272 |
4 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 4.42916471 |
5 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.92421242 |
6 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.36709524 |
7 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 3.29193760 |
8 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.16297996 |
9 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.14119815 |
10 | AR_21909140_ChIP-Seq_LNCAP_Human | 3.05570696 |
11 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.77037556 |
12 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.67603290 |
13 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.66812931 |
14 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.59742812 |
15 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.40294881 |
16 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.32587635 |
17 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.30945352 |
18 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.28907250 |
19 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.22964720 |
20 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.20867521 |
21 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.16013898 |
22 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.10581634 |
23 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 2.10157339 |
24 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.09542213 |
25 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.05078483 |
26 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.05073261 |
27 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.98273249 |
28 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.96699615 |
29 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.91161824 |
30 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.89950119 |
31 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.87834414 |
32 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.86652012 |
33 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.80296785 |
34 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.78471410 |
35 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.74923558 |
36 | MYC_22102868_ChIP-Seq_BL_Human | 1.69838369 |
37 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.67494538 |
38 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.56772023 |
39 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.56110944 |
40 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.54977743 |
41 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.53000528 |
42 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.51175669 |
43 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.50831111 |
44 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.48399925 |
45 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.48118803 |
46 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.47756054 |
47 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.46977984 |
48 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.44620101 |
49 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.42563992 |
50 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.42517586 |
51 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.41438285 |
52 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.40113192 |
53 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.37882773 |
54 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.36904318 |
55 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.34989453 |
56 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.28425279 |
57 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.25254481 |
58 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.23351055 |
59 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.19523092 |
60 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.17123634 |
61 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.16306799 |
62 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.15269329 |
63 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.13918654 |
64 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.12933291 |
65 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.11124439 |
66 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.05336070 |
67 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.04526314 |
68 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.03960434 |
69 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02687811 |
70 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.02526955 |
71 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.01683181 |
72 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.98705636 |
73 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.96747782 |
74 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.96062992 |
75 | * CHD1_26751641_Chip-Seq_LNCaP_Human | 0.95822290 |
76 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.93881022 |
77 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.91139869 |
78 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.90328482 |
79 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.88932652 |
80 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.88565161 |
81 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.88129597 |
82 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.86751742 |
83 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.83763911 |
84 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.83586323 |
85 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.83581071 |
86 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.82268607 |
87 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.81115821 |
88 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.80765616 |
89 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.79780628 |
90 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.79747380 |
91 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.76827120 |
92 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.75948835 |
93 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.75136956 |
94 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.75098421 |
95 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.74946653 |
96 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.74644565 |
97 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.74598327 |
98 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.74223953 |
99 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.71395331 |
100 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.71158225 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 5.71088799 |
2 | MP0010094_abnormal_chromosome_stability | 5.38990320 |
3 | MP0003111_abnormal_nucleus_morphology | 5.30489472 |
4 | MP0004957_abnormal_blastocyst_morpholog | 4.62476346 |
5 | MP0003077_abnormal_cell_cycle | 4.38510007 |
6 | MP0008057_abnormal_DNA_replication | 4.26770006 |
7 | MP0008058_abnormal_DNA_repair | 3.71151377 |
8 | MP0008932_abnormal_embryonic_tissue | 3.21569808 |
9 | MP0008007_abnormal_cellular_replicative | 2.90824000 |
10 | MP0001730_embryonic_growth_arrest | 2.52270448 |
11 | MP0000350_abnormal_cell_proliferation | 2.37369749 |
12 | MP0003718_maternal_effect | 2.13018507 |
13 | MP0002877_abnormal_melanocyte_morpholog | 2.12984996 |
14 | MP0010307_abnormal_tumor_latency | 2.12370878 |
15 | MP0009697_abnormal_copulation | 2.08326441 |
16 | MP0001697_abnormal_embryo_size | 1.97867816 |
17 | MP0005380_embryogenesis_phenotype | 1.93342170 |
18 | MP0001672_abnormal_embryogenesis/_devel | 1.93342170 |
19 | MP0005076_abnormal_cell_differentiation | 1.86207367 |
20 | MP0002080_prenatal_lethality | 1.80428480 |
21 | MP0003786_premature_aging | 1.79494561 |
22 | MP0002396_abnormal_hematopoietic_system | 1.75314320 |
23 | MP0000313_abnormal_cell_death | 1.72278293 |
24 | MP0003984_embryonic_growth_retardation | 1.70178493 |
25 | MP0002088_abnormal_embryonic_growth/wei | 1.62942671 |
26 | MP0004233_abnormal_muscle_weight | 1.61102477 |
27 | MP0010352_gastrointestinal_tract_polyps | 1.60704254 |
28 | MP0004185_abnormal_adipocyte_glucose | 1.50786635 |
29 | MP0002085_abnormal_embryonic_tissue | 1.50703272 |
30 | MP0005451_abnormal_body_composition | 1.47619663 |
31 | MP0009672_abnormal_birth_weight | 1.41180488 |
32 | MP0002084_abnormal_developmental_patter | 1.40919381 |
33 | MP0002086_abnormal_extraembryonic_tissu | 1.39924897 |
34 | MP0003656_abnormal_erythrocyte_physiolo | 1.32457957 |
35 | MP0002210_abnormal_sex_determination | 1.30513449 |
36 | MP0002009_preneoplasia | 1.30195565 |
37 | MP0006035_abnormal_mitochondrial_morpho | 1.27952446 |
38 | MP0004808_abnormal_hematopoietic_stem | 1.27747638 |
39 | MP0010234_abnormal_vibrissa_follicle | 1.27138345 |
40 | MP0003890_abnormal_embryonic-extraembry | 1.25472879 |
41 | MP0004197_abnormal_fetal_growth/weight/ | 1.23384562 |
42 | MP0006292_abnormal_olfactory_placode | 1.23335436 |
43 | MP0002019_abnormal_tumor_incidence | 1.23098943 |
44 | MP0003941_abnormal_skin_development | 1.21391546 |
45 | MP0004147_increased_porphyrin_level | 1.18706516 |
46 | MP0001929_abnormal_gametogenesis | 1.17689601 |
47 | MP0003705_abnormal_hypodermis_morpholog | 1.14600859 |
48 | MP0000358_abnormal_cell_content/ | 1.12798278 |
49 | MP0005501_abnormal_skin_physiology | 1.12627585 |
50 | MP0008995_early_reproductive_senescence | 1.11293463 |
51 | MP0000490_abnormal_crypts_of | 1.11041713 |
52 | MP0003806_abnormal_nucleotide_metabolis | 1.09004502 |
53 | MP0000678_abnormal_parathyroid_gland | 1.08737558 |
54 | MP0001661_extended_life_span | 1.04534438 |
55 | MP0001145_abnormal_male_reproductive | 1.03965086 |
56 | MP0003221_abnormal_cardiomyocyte_apopto | 1.02607927 |
57 | MP0002796_impaired_skin_barrier | 1.01636173 |
58 | MP0005621_abnormal_cell_physiology | 0.95643010 |
59 | MP0005384_cellular_phenotype | 0.93821710 |
60 | MP0008877_abnormal_DNA_methylation | 0.90910780 |
61 | MP0006036_abnormal_mitochondrial_physio | 0.89435149 |
62 | MP0000653_abnormal_sex_gland | 0.89341237 |
63 | MP0003937_abnormal_limbs/digits/tail_de | 0.89293873 |
64 | MP0000703_abnormal_thymus_morphology | 0.85841471 |
65 | MP0003699_abnormal_female_reproductive | 0.85338994 |
66 | MP0001727_abnormal_embryo_implantation | 0.83065585 |
67 | MP0001293_anophthalmia | 0.82840544 |
68 | MP0003567_abnormal_fetal_cardiomyocyte | 0.81139022 |
69 | MP0009703_decreased_birth_body | 0.81024958 |
70 | MP0002697_abnormal_eye_size | 0.79124976 |
71 | MP0001346_abnormal_lacrimal_gland | 0.75028703 |
72 | MP0010030_abnormal_orbit_morphology | 0.73446958 |
73 | MP0002111_abnormal_tail_morphology | 0.72623477 |
74 | MP0002161_abnormal_fertility/fecundity | 0.72438755 |
75 | MP0003186_abnormal_redox_activity | 0.69810794 |
76 | MP0001881_abnormal_mammary_gland | 0.68245013 |
77 | MP0003698_abnormal_male_reproductive | 0.67772284 |
78 | MP0003315_abnormal_perineum_morphology | 0.67523436 |
79 | MP0000428_abnormal_craniofacial_morphol | 0.67394787 |
80 | MP0000537_abnormal_urethra_morphology | 0.65830232 |
81 | MP0004264_abnormal_extraembryonic_tissu | 0.62122485 |
82 | MP0002092_abnormal_eye_morphology | 0.61941351 |
83 | MP0003950_abnormal_plasma_membrane | 0.61937965 |
84 | MP0001286_abnormal_eye_development | 0.61917465 |
85 | MP0001119_abnormal_female_reproductive | 0.60990172 |
86 | MP0003943_abnormal_hepatobiliary_system | 0.59750137 |
87 | MP0002160_abnormal_reproductive_system | 0.59551915 |
88 | MP0001853_heart_inflammation | 0.58916469 |
89 | MP0003453_abnormal_keratinocyte_physiol | 0.58200388 |
90 | MP0005395_other_phenotype | 0.57530688 |
91 | MP0003123_paternal_imprinting | 0.57457116 |
92 | MP0002722_abnormal_immune_system | 0.55044089 |
93 | MP0002398_abnormal_bone_marrow | 0.55010538 |
94 | MP0002269_muscular_atrophy | 0.54478774 |
95 | MP0002970_abnormal_white_adipose | 0.54347401 |
96 | MP0001915_intracranial_hemorrhage | 0.54145986 |
97 | MP0001216_abnormal_epidermal_layer | 0.53960505 |
98 | MP0000627_abnormal_mammary_gland | 0.52023888 |
99 | MP0003566_abnormal_cell_adhesion | 0.52012143 |
100 | MP0003861_abnormal_nervous_system | 0.50782101 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 6.14965359 |
2 | Chromsome breakage (HP:0040012) | 5.93584944 |
3 | Increased nuchal translucency (HP:0010880) | 4.19251979 |
4 | Cortical dysplasia (HP:0002539) | 3.86964432 |
5 | Abnormality of chromosome stability (HP:0003220) | 3.64903566 |
6 | Abnormality of the preputium (HP:0100587) | 3.64726699 |
7 | Nephroblastoma (Wilms tumor) (HP:0002667) | 3.60821289 |
8 | Birth length less than 3rd percentile (HP:0003561) | 3.49908251 |
9 | Meckel diverticulum (HP:0002245) | 3.48775053 |
10 | Small intestinal stenosis (HP:0012848) | 3.44943132 |
11 | Duodenal stenosis (HP:0100867) | 3.44943132 |
12 | Reticulocytopenia (HP:0001896) | 3.42855784 |
13 | Embryonal renal neoplasm (HP:0011794) | 3.38427858 |
14 | Abnormal lung lobation (HP:0002101) | 3.36242690 |
15 | Myelodysplasia (HP:0002863) | 3.29766366 |
16 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.28631023 |
17 | Abnormality of the ileum (HP:0001549) | 3.26763625 |
18 | Abnormal gallbladder physiology (HP:0012438) | 3.13512231 |
19 | Cholecystitis (HP:0001082) | 3.13512231 |
20 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.84247116 |
21 | Volvulus (HP:0002580) | 2.82479809 |
22 | Abnormality of the duodenum (HP:0002246) | 2.79642919 |
23 | Progressive external ophthalmoplegia (HP:0000590) | 2.79276756 |
24 | Progressive muscle weakness (HP:0003323) | 2.76313190 |
25 | Abnormality of reticulocytes (HP:0004312) | 2.73242716 |
26 | Microvesicular hepatic steatosis (HP:0001414) | 2.72365546 |
27 | Cafe-au-lait spot (HP:0000957) | 2.70494338 |
28 | Overlapping toe (HP:0001845) | 2.67145247 |
29 | Abnormality of the carotid arteries (HP:0005344) | 2.52240304 |
30 | Multiple enchondromatosis (HP:0005701) | 2.44214665 |
31 | Proximal placement of thumb (HP:0009623) | 2.44185424 |
32 | Abnormality of glycolysis (HP:0004366) | 2.40929499 |
33 | Reticulocytosis (HP:0001923) | 2.40268104 |
34 | Sloping forehead (HP:0000340) | 2.40245711 |
35 | Deviation of the thumb (HP:0009603) | 2.34027274 |
36 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.33653583 |
37 | Rhabdomyosarcoma (HP:0002859) | 2.33109452 |
38 | Squamous cell carcinoma (HP:0002860) | 2.30987752 |
39 | Deep philtrum (HP:0002002) | 2.30378634 |
40 | Abnormality of chromosome segregation (HP:0002916) | 2.29426103 |
41 | Embryonal neoplasm (HP:0002898) | 2.28644569 |
42 | Horseshoe kidney (HP:0000085) | 2.28089620 |
43 | Absent radius (HP:0003974) | 2.26760728 |
44 | Choanal atresia (HP:0000453) | 2.22797949 |
45 | Abnormality of cochlea (HP:0000375) | 2.21489429 |
46 | Increased serum pyruvate (HP:0003542) | 2.20224561 |
47 | Selective tooth agenesis (HP:0001592) | 2.20223177 |
48 | Breast hypoplasia (HP:0003187) | 2.20152811 |
49 | Ectopic kidney (HP:0000086) | 2.19101245 |
50 | Premature ovarian failure (HP:0008209) | 2.18618996 |
51 | Pallor (HP:0000980) | 2.17469484 |
52 | Ankyloglossia (HP:0010296) | 2.13830487 |
53 | Duplicated collecting system (HP:0000081) | 2.09635486 |
54 | Missing ribs (HP:0000921) | 2.07435179 |
55 | Aplasia involving forearm bones (HP:0009822) | 2.06446926 |
56 | Absent forearm bone (HP:0003953) | 2.06446926 |
57 | 11 pairs of ribs (HP:0000878) | 2.06424245 |
58 | Neoplasm of the colon (HP:0100273) | 2.04827501 |
59 | Arteriovenous malformation (HP:0100026) | 2.02183228 |
60 | Abnormal number of erythroid precursors (HP:0012131) | 1.96181576 |
61 | Macrocytic anemia (HP:0001972) | 1.95529724 |
62 | Acute myeloid leukemia (HP:0004808) | 1.95416029 |
63 | Medulloblastoma (HP:0002885) | 1.94248228 |
64 | Carpal bone hypoplasia (HP:0001498) | 1.93276686 |
65 | Orthostatic hypotension (HP:0001278) | 1.92625500 |
66 | Abnormality of DNA repair (HP:0003254) | 1.89026088 |
67 | Poikiloderma (HP:0001029) | 1.86577923 |
68 | Septate vagina (HP:0001153) | 1.86091939 |
69 | Absent thumb (HP:0009777) | 1.84388087 |
70 | Facial hemangioma (HP:0000329) | 1.83786431 |
71 | Insomnia (HP:0100785) | 1.83640882 |
72 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.83192813 |
73 | Triphalangeal thumb (HP:0001199) | 1.82500512 |
74 | Clubbing of toes (HP:0100760) | 1.81954034 |
75 | Microglossia (HP:0000171) | 1.79308987 |
76 | Cholelithiasis (HP:0001081) | 1.79095102 |
77 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.78707677 |
78 | Bone marrow hypocellularity (HP:0005528) | 1.78135424 |
79 | Atresia of the external auditory canal (HP:0000413) | 1.77259689 |
80 | Hypergonadotropic hypogonadism (HP:0000815) | 1.76665072 |
81 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.75815420 |
82 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.75815420 |
83 | Single umbilical artery (HP:0001195) | 1.75815420 |
84 | Ureteral duplication (HP:0000073) | 1.72966626 |
85 | Duplication of thumb phalanx (HP:0009942) | 1.72622420 |
86 | Uterine leiomyosarcoma (HP:0002891) | 1.71931357 |
87 | Leiomyosarcoma (HP:0100243) | 1.71931357 |
88 | Nonimmune hydrops fetalis (HP:0001790) | 1.71381285 |
89 | Abnormality of the renal collecting system (HP:0004742) | 1.71227728 |
90 | Secondary amenorrhea (HP:0000869) | 1.70653402 |
91 | Short middle phalanx of the 5th finger (HP:0004220) | 1.70503312 |
92 | Insidious onset (HP:0003587) | 1.69763100 |
93 | Termporal pattern (HP:0011008) | 1.69763100 |
94 | Truncus arteriosus (HP:0001660) | 1.68327873 |
95 | Upper limb muscle weakness (HP:0003484) | 1.68090339 |
96 | Sandal gap (HP:0001852) | 1.66474531 |
97 | Abnormality of the umbilical cord (HP:0010881) | 1.66317653 |
98 | Ependymoma (HP:0002888) | 1.65480995 |
99 | Obsessive-compulsive behavior (HP:0000722) | 1.64801334 |
100 | Hypoparathyroidism (HP:0000829) | 1.63462795 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 5.86500604 |
2 | TTK | 4.61733101 |
3 | CDC7 | 3.68181602 |
4 | NEK1 | 3.07316151 |
5 | WEE1 | 2.93033426 |
6 | SRPK1 | 2.85004704 |
7 | PBK | 2.76463248 |
8 | EIF2AK1 | 2.69018934 |
9 | PLK4 | 2.55315404 |
10 | NEK2 | 2.26793153 |
11 | TSSK6 | 2.13107641 |
12 | CDK12 | 2.04498441 |
13 | BRSK2 | 2.02607854 |
14 | PLK1 | 1.87494913 |
15 | SCYL2 | 1.87077066 |
16 | PLK3 | 1.84594269 |
17 | CHEK2 | 1.79125517 |
18 | MAP3K10 | 1.76170883 |
19 | NME2 | 1.73396751 |
20 | BRSK1 | 1.72967603 |
21 | BRAF | 1.61619733 |
22 | SMG1 | 1.61596762 |
23 | EEF2K | 1.56478210 |
24 | EIF2AK3 | 1.54554404 |
25 | VRK2 | 1.53329848 |
26 | AURKB | 1.50819020 |
27 | MAP3K8 | 1.45776980 |
28 | ATR | 1.43823201 |
29 | CCNB1 | 1.38058561 |
30 | RPS6KB2 | 1.36822540 |
31 | CHEK1 | 1.34450850 |
32 | CLK1 | 1.33394530 |
33 | CDK7 | 1.30075521 |
34 | TAF1 | 1.28108041 |
35 | STK10 | 1.24680939 |
36 | MKNK1 | 1.23607608 |
37 | MST4 | 1.20362506 |
38 | AURKA | 1.16699949 |
39 | CDK4 | 1.15088131 |
40 | STK4 | 1.11408790 |
41 | ZAK | 1.00459801 |
42 | PNCK | 0.98243634 |
43 | EIF2AK2 | 0.94910396 |
44 | IRAK3 | 0.93420028 |
45 | KSR2 | 0.91166934 |
46 | RPS6KA4 | 0.90585639 |
47 | ICK | 0.90525767 |
48 | MST1R | 0.89080826 |
49 | ATM | 0.87346969 |
50 | MKNK2 | 0.87137272 |
51 | BRD4 | 0.86256843 |
52 | RAF1 | 0.84708556 |
53 | CDK1 | 0.83062304 |
54 | CDK8 | 0.81533211 |
55 | LATS2 | 0.80988949 |
56 | VRK1 | 0.77395804 |
57 | TRIB3 | 0.77314487 |
58 | STK3 | 0.75485253 |
59 | ALK | 0.74894936 |
60 | CDK2 | 0.74119861 |
61 | DYRK3 | 0.71162319 |
62 | NME1 | 0.70324544 |
63 | MET | 0.70139707 |
64 | STK16 | 0.70099677 |
65 | PAK4 | 0.68470429 |
66 | PASK | 0.68261798 |
67 | PRPF4B | 0.67695960 |
68 | CDK6 | 0.64440784 |
69 | BMX | 0.62429754 |
70 | MELK | 0.61412812 |
71 | ARAF | 0.51943721 |
72 | KSR1 | 0.51828850 |
73 | CDK11A | 0.49866459 |
74 | CSNK2A2 | 0.49512875 |
75 | PAK1 | 0.48779426 |
76 | BMPR2 | 0.48737728 |
77 | CSNK2A1 | 0.45449189 |
78 | CDK15 | 0.44810159 |
79 | CDK18 | 0.43993686 |
80 | MTOR | 0.43758982 |
81 | MAP3K9 | 0.42250015 |
82 | TAOK2 | 0.41110079 |
83 | AKT2 | 0.40183244 |
84 | TESK2 | 0.39619769 |
85 | CSNK1E | 0.38576626 |
86 | CDK14 | 0.38097083 |
87 | CDK3 | 0.37710816 |
88 | YES1 | 0.36352839 |
89 | CDK9 | 0.36135670 |
90 | PRKCI | 0.35843321 |
91 | ERBB4 | 0.33213532 |
92 | TRIM28 | 0.32894853 |
93 | MARK3 | 0.29593060 |
94 | PRKDC | 0.29567788 |
95 | MAP3K13 | 0.28915485 |
96 | NEK9 | 0.28741275 |
97 | MAPK14 | 0.26685225 |
98 | PDK2 | 0.26175030 |
99 | PIM1 | 0.24681156 |
100 | DMPK | 0.20969122 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.94926135 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 4.25135249 |
3 | Cell cycle_Homo sapiens_hsa04110 | 3.56037840 |
4 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 3.28909068 |
5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.14415173 |
6 | Homologous recombination_Homo sapiens_hsa03440 | 3.05389912 |
7 | Base excision repair_Homo sapiens_hsa03410 | 2.99104406 |
8 | Spliceosome_Homo sapiens_hsa03040 | 2.92829372 |
9 | RNA transport_Homo sapiens_hsa03013 | 2.88342476 |
10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.74332817 |
11 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.68297278 |
12 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.62067870 |
13 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.48261432 |
14 | Ribosome_Homo sapiens_hsa03010 | 2.26422094 |
15 | Proteasome_Homo sapiens_hsa03050 | 2.12676955 |
16 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.02195483 |
17 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.73330605 |
18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.68134080 |
19 | RNA polymerase_Homo sapiens_hsa03020 | 1.66055892 |
20 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.65016526 |
21 | RNA degradation_Homo sapiens_hsa03018 | 1.56167687 |
22 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.55088443 |
23 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.49898785 |
24 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.45925252 |
25 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.31390652 |
26 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.26599345 |
27 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.24599211 |
28 | Thyroid cancer_Homo sapiens_hsa05216 | 1.14790478 |
29 | Carbon metabolism_Homo sapiens_hsa01200 | 1.13310832 |
30 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.11600869 |
31 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.10818538 |
32 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.03317869 |
33 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.02503958 |
34 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.01508499 |
35 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.96502590 |
36 | Purine metabolism_Homo sapiens_hsa00230 | 0.95775740 |
37 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.95204169 |
38 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.92988882 |
39 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.87459671 |
40 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.86121809 |
41 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.85633219 |
42 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.85295853 |
43 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.79282308 |
44 | Bladder cancer_Homo sapiens_hsa05219 | 0.77155470 |
45 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.76574862 |
46 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.76165687 |
47 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.75417812 |
48 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.74553577 |
49 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.71888441 |
50 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.71449625 |
51 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.70320575 |
52 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.70201815 |
53 | HTLV-I infection_Homo sapiens_hsa05166 | 0.66413891 |
54 | Protein export_Homo sapiens_hsa03060 | 0.66325092 |
55 | Sulfur relay system_Homo sapiens_hsa04122 | 0.66160407 |
56 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.64558938 |
57 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.61480621 |
58 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.60641494 |
59 | Lysine degradation_Homo sapiens_hsa00310 | 0.56390796 |
60 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.55090796 |
61 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.54753156 |
62 | Prostate cancer_Homo sapiens_hsa05215 | 0.54040829 |
63 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.53556037 |
64 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.53408257 |
65 | Colorectal cancer_Homo sapiens_hsa05210 | 0.53165585 |
66 | Hepatitis B_Homo sapiens_hsa05161 | 0.51890514 |
67 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.45007153 |
68 | Apoptosis_Homo sapiens_hsa04210 | 0.43882694 |
69 | Huntingtons disease_Homo sapiens_hsa05016 | 0.43044113 |
70 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.42116407 |
71 | Adherens junction_Homo sapiens_hsa04520 | 0.41587534 |
72 | Shigellosis_Homo sapiens_hsa05131 | 0.39923041 |
73 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.39547141 |
74 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.34160615 |
75 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.33560727 |
76 | Glioma_Homo sapiens_hsa05214 | 0.33417449 |
77 | Endometrial cancer_Homo sapiens_hsa05213 | 0.33187845 |
78 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.33184031 |
79 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.31548657 |
80 | Galactose metabolism_Homo sapiens_hsa00052 | 0.29116910 |
81 | Alcoholism_Homo sapiens_hsa05034 | 0.28969771 |
82 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.28503897 |
83 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.28052417 |
84 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.27844134 |
85 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.26226582 |
86 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.26105181 |
87 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.23698345 |
88 | Melanoma_Homo sapiens_hsa05218 | 0.22865404 |
89 | Parkinsons disease_Homo sapiens_hsa05012 | 0.21915587 |
90 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.20993659 |
91 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.20311046 |
92 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.19951037 |
93 | Metabolic pathways_Homo sapiens_hsa01100 | 0.19523022 |
94 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.19296828 |
95 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.19169234 |
96 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.18938254 |
97 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.18090414 |
98 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.17680142 |
99 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.17479027 |
100 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.15498072 |