FAM57B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a transmembrane protein, which may be a likely target of peroxisome proliferator-activated receptor gamma (PPAR-gamma). The product of the orthologous gene in mouse is related to obesity. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of rhodopsin mediated signaling pathway (GO:0022400)8.47967558
2rhodopsin mediated signaling pathway (GO:0016056)8.36848050
3retinal cone cell development (GO:0046549)6.57800526
4photoreceptor cell development (GO:0042461)6.42369821
5regulation of short-term neuronal synaptic plasticity (GO:0048172)6.07078489
6positive regulation of calcium ion-dependent exocytosis (GO:0045956)6.02314420
7photoreceptor cell maintenance (GO:0045494)6.02199307
8eye photoreceptor cell development (GO:0042462)5.98882978
9synaptic vesicle maturation (GO:0016188)5.79186606
10detection of light stimulus involved in sensory perception (GO:0050962)5.70241593
11detection of light stimulus involved in visual perception (GO:0050908)5.70241593
12retinal rod cell development (GO:0046548)5.49435172
13phototransduction (GO:0007602)5.21848901
14behavioral response to nicotine (GO:0035095)5.17336521
15protein localization to synapse (GO:0035418)5.07656033
16detection of light stimulus (GO:0009583)5.03984482
17positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.99661337
18GMP metabolic process (GO:0046037)4.90863992
19phototransduction, visible light (GO:0007603)4.89190708
20regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.87310278
21detection of visible light (GO:0009584)4.82682008
22synaptic vesicle exocytosis (GO:0016079)4.73812273
23glutamate secretion (GO:0014047)4.63062884
24regulation of synaptic vesicle exocytosis (GO:2000300)4.61823820
25membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.59288555
26response to pheromone (GO:0019236)4.57817089
27synaptic vesicle docking involved in exocytosis (GO:0016081)4.55911159
28locomotory exploration behavior (GO:0035641)4.52308777
29visual perception (GO:0007601)4.48458704
30vocalization behavior (GO:0071625)4.47058515
31sensory perception of light stimulus (GO:0050953)4.43598216
32positive regulation of guanylate cyclase activity (GO:0031284)4.23984684
33regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.23882603
34cellular potassium ion homeostasis (GO:0030007)4.14277438
35regulation of synaptic vesicle transport (GO:1902803)4.12018503
36protein-chromophore linkage (GO:0018298)4.09805409
37nucleobase catabolic process (GO:0046113)4.06154778
38layer formation in cerebral cortex (GO:0021819)4.05807467
39sodium ion export (GO:0071436)4.05484645
40positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.04410342
41transmission of nerve impulse (GO:0019226)3.97724486
42auditory behavior (GO:0031223)3.93724307
43regulation of clathrin-mediated endocytosis (GO:2000369)3.90858780
44negative regulation of synaptic transmission, GABAergic (GO:0032229)3.90073378
45presynaptic membrane assembly (GO:0097105)3.87894519
46neurotransmitter secretion (GO:0007269)3.87178920
47photoreceptor cell differentiation (GO:0046530)3.86260281
48eye photoreceptor cell differentiation (GO:0001754)3.86260281
49regulation of glutamate receptor signaling pathway (GO:1900449)3.83673346
50neuromuscular synaptic transmission (GO:0007274)3.83490987
51regulation of guanylate cyclase activity (GO:0031282)3.82080026
52retina development in camera-type eye (GO:0060041)3.80718617
53neuron cell-cell adhesion (GO:0007158)3.75886323
54presynaptic membrane organization (GO:0097090)3.73339761
55detection of external stimulus (GO:0009581)3.73004957
56detection of abiotic stimulus (GO:0009582)3.65471958
57cell migration in hindbrain (GO:0021535)3.56046955
58dendritic spine morphogenesis (GO:0060997)3.53977689
59membrane hyperpolarization (GO:0060081)3.53387477
60positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.50424293
61cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.47611135
62positive regulation of membrane potential (GO:0045838)3.45320402
63cellular response to light stimulus (GO:0071482)3.44595802
64synaptic transmission, glutamatergic (GO:0035249)3.43782048
65G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.43398644
66exploration behavior (GO:0035640)3.41812590
67regulation of voltage-gated calcium channel activity (GO:1901385)3.41398893
68neurotransmitter transport (GO:0006836)3.39883017
69ionotropic glutamate receptor signaling pathway (GO:0035235)3.39419016
70regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.39189622
71cerebellar Purkinje cell differentiation (GO:0021702)3.37382194
72neuronal action potential propagation (GO:0019227)3.37119044
73cell communication by electrical coupling (GO:0010644)3.36538085
74regulation of vesicle fusion (GO:0031338)3.32142563
75regulation of neurotransmitter levels (GO:0001505)3.31132926
76regulation of neurotransmitter secretion (GO:0046928)3.30105825
77proline transport (GO:0015824)3.29159316
78positive regulation of synapse maturation (GO:0090129)3.28637808
79mechanosensory behavior (GO:0007638)3.28566289
80potassium ion homeostasis (GO:0055075)3.28536379
81neuron recognition (GO:0008038)3.27657396
82establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.27377277
83mitochondrion transport along microtubule (GO:0047497)3.27377277
84neuron-neuron synaptic transmission (GO:0007270)3.25448052
85regulation of neuronal synaptic plasticity (GO:0048168)3.22892670
86regulation of postsynaptic membrane potential (GO:0060078)3.22512908
87positive regulation of neurotransmitter transport (GO:0051590)3.21223846
88startle response (GO:0001964)3.18050088
89regulation of excitatory postsynaptic membrane potential (GO:0060079)3.17791002
90gamma-aminobutyric acid transport (GO:0015812)3.17421521
91pyrimidine nucleobase catabolic process (GO:0006208)3.17032800
92innervation (GO:0060384)3.16088841
93dendrite morphogenesis (GO:0048813)3.15823191
94membrane depolarization (GO:0051899)3.14248685
95glutamate receptor signaling pathway (GO:0007215)3.10774401
96synaptic vesicle endocytosis (GO:0048488)3.09844049
97chemosensory behavior (GO:0007635)3.08856248
98regulation of respiratory system process (GO:0044065)3.08674842
99synapse assembly (GO:0007416)3.08668734
100neurotransmitter-gated ion channel clustering (GO:0072578)3.07833152
101regulation of long-term neuronal synaptic plasticity (GO:0048169)3.07052860
102establishment of mitochondrion localization (GO:0051654)3.06188207
103negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.03622894
104regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.02971286
105regulation of cGMP metabolic process (GO:0030823)3.01285257
106long-term memory (GO:0007616)3.00214039
107response to auditory stimulus (GO:0010996)2.97751214
108neuronal ion channel clustering (GO:0045161)2.97265197
109dopamine receptor signaling pathway (GO:0007212)2.96048681
110negative regulation of cytosolic calcium ion concentration (GO:0051481)2.95922385
111positive regulation of dendritic spine development (GO:0060999)2.94839097
112righting reflex (GO:0060013)2.93746250
113axonal fasciculation (GO:0007413)2.93039053
114regulation of synapse structural plasticity (GO:0051823)2.91792133
115potassium ion import (GO:0010107)2.91687925
116neuromuscular process controlling posture (GO:0050884)2.91458245
117postsynaptic membrane organization (GO:0001941)2.90393881
118regulation of synaptic transmission, glutamatergic (GO:0051966)2.90163775
119regulation of neurotransmitter transport (GO:0051588)2.89087005
120membrane depolarization during action potential (GO:0086010)2.88993933
121behavioral defense response (GO:0002209)2.87566815
122behavioral fear response (GO:0001662)2.87566815
123regulation of neurotransmitter uptake (GO:0051580)2.86734893
124adult walking behavior (GO:0007628)2.85867587
125neuronal action potential (GO:0019228)2.85373021
126regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.84843287
127positive regulation of potassium ion transmembrane transport (GO:1901381)2.84657718
128axon cargo transport (GO:0008088)2.83750956
129behavioral response to ethanol (GO:0048149)2.82826628
130glycine transport (GO:0015816)2.82496465
131regulation of respiratory gaseous exchange (GO:0043576)2.81196189
132synaptic transmission (GO:0007268)2.78910610
133social behavior (GO:0035176)2.75994108
134intraspecies interaction between organisms (GO:0051703)2.75994108
135central nervous system myelination (GO:0022010)2.75446295
136axon ensheathment in central nervous system (GO:0032291)2.75446295
137adult behavior (GO:0030534)2.73570742
138fear response (GO:0042596)2.73509370
139positive regulation of synapse assembly (GO:0051965)2.72914477
140synaptic transmission, cholinergic (GO:0007271)2.71975528
141spinal cord development (GO:0021510)2.71001197
142regulation of calcium ion-dependent exocytosis (GO:0017158)2.70135686
143regulation of synapse maturation (GO:0090128)2.68822514
144protein localization to cilium (GO:0061512)2.67620173
145synapse organization (GO:0050808)2.66702567

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.18727846
2CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.90324513
3GBX2_23144817_ChIP-Seq_PC3_Human2.89695376
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.88273672
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.86999743
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.82047139
7* REST_21632747_ChIP-Seq_MESCs_Mouse2.75836551
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.70045606
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.70045606
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.66125972
11DROSHA_22980978_ChIP-Seq_HELA_Human2.61437533
12EZH2_27294783_Chip-Seq_ESCs_Mouse2.53209347
13* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.53173764
14EZH2_27304074_Chip-Seq_ESCs_Mouse2.51842837
15MTF2_20144788_ChIP-Seq_MESCs_Mouse2.44802785
16* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.43541407
17REST_18959480_ChIP-ChIP_MESCs_Mouse2.42020067
18RARB_27405468_Chip-Seq_BRAIN_Mouse2.39899782
19SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.35869242
20EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.29625454
21SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.24783507
22RNF2_27304074_Chip-Seq_ESCs_Mouse2.21856186
23SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.18999425
24NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.02875123
25IKZF1_21737484_ChIP-ChIP_HCT116_Human1.99099020
26EED_16625203_ChIP-ChIP_MESCs_Mouse1.96218772
27ZFP57_27257070_Chip-Seq_ESCs_Mouse1.92289135
28CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.88501185
29MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.86140886
30ERG_21242973_ChIP-ChIP_JURKAT_Human1.82425549
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.75168883
32AR_21572438_ChIP-Seq_LNCaP_Human1.68479249
33GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.66576398
34KDM2B_26808549_Chip-Seq_K562_Human1.59482775
35TAF15_26573619_Chip-Seq_HEK293_Human1.58888844
36SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.51860255
37RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.46176443
38RING1B_27294783_Chip-Seq_ESCs_Mouse1.44324293
39* RING1B_27294783_Chip-Seq_NPCs_Mouse1.42447908
40ZNF274_21170338_ChIP-Seq_K562_Hela1.41123776
41CTBP2_25329375_ChIP-Seq_LNCAP_Human1.40119034
42SMAD4_21799915_ChIP-Seq_A2780_Human1.38331249
43TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.36701277
44ZFP281_18757296_ChIP-ChIP_E14_Mouse1.36402998
45POU3F2_20337985_ChIP-ChIP_501MEL_Human1.36322237
46PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.35665958
47FUS_26573619_Chip-Seq_HEK293_Human1.34816681
48AR_19668381_ChIP-Seq_PC3_Human1.33263833
49CTCF_27219007_Chip-Seq_Bcells_Human1.31481225
50CTBP1_25329375_ChIP-Seq_LNCAP_Human1.30367907
51PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.29578524
52GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29220851
53P53_22127205_ChIP-Seq_FIBROBLAST_Human1.24678634
54CBX2_27304074_Chip-Seq_ESCs_Mouse1.23049434
55EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.22884975
56RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.21143053
57DNAJC2_21179169_ChIP-ChIP_NT2_Human1.21046289
58BMI1_23680149_ChIP-Seq_NPCS_Mouse1.19583370
59HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.17492937
60MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.16969624
61SOX2_21211035_ChIP-Seq_LN229_Gbm1.14839154
62OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.12300790
63WT1_25993318_ChIP-Seq_PODOCYTE_Human1.11781044
64IGF1R_20145208_ChIP-Seq_DFB_Human1.08732907
65CBP_20019798_ChIP-Seq_JUKART_Human1.08657015
66IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.08657015
67UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.08588445
68GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.08485785
69TOP2B_26459242_ChIP-Seq_MCF-7_Human1.08234936
70STAT3_23295773_ChIP-Seq_U87_Human1.07805004
71ER_23166858_ChIP-Seq_MCF-7_Human1.07337649
72NR3C1_23031785_ChIP-Seq_PC12_Mouse1.07065024
73SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.06774245
74VDR_22108803_ChIP-Seq_LS180_Human1.06610535
75MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.05861210
76FLI1_27457419_Chip-Seq_LIVER_Mouse1.04009561
77GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.03905976
78* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.02833154
79TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.02630077
80E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.02382311
81ETV2_25802403_ChIP-Seq_MESCs_Mouse1.01982724
82YAP1_20516196_ChIP-Seq_MESCs_Mouse1.01822378
83TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.01600176
84TP53_22573176_ChIP-Seq_HFKS_Human1.00694206
85RNF2_27304074_Chip-Seq_NSC_Mouse1.00650834
86KLF5_20875108_ChIP-Seq_MESCs_Mouse1.00629055
87PIAS1_25552417_ChIP-Seq_VCAP_Human1.00592680
88SMAD3_21741376_ChIP-Seq_HESCs_Human1.00489250
89RUNX2_22187159_ChIP-Seq_PCA_Human1.00487211
90CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.99811762
91SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.99460288
92TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99338845
93SALL1_21062744_ChIP-ChIP_HESCs_Human0.98597920
94WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.98270804
95P300_19829295_ChIP-Seq_ESCs_Human0.98061609
96SMAD3_21741376_ChIP-Seq_ESCs_Human0.97554308
97TET1_21490601_ChIP-Seq_MESCs_Mouse0.97206083
98RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.96882130
99SMAD4_21741376_ChIP-Seq_HESCs_Human0.96589172
100OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.96345071
101FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.95972832
102EWS_26573619_Chip-Seq_HEK293_Human0.94949948
103BCAT_22108803_ChIP-Seq_LS180_Human0.94693674
104MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.94077327
105ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.93928405
106DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.93689463
107AR_25329375_ChIP-Seq_VCAP_Human0.92923285
108NR3C1_21868756_ChIP-Seq_MCF10A_Human0.92146784
109CDX2_19796622_ChIP-Seq_MESCs_Mouse0.92088399
110AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.91243721
111SMAD3_21741376_ChIP-Seq_EPCs_Human0.91154409
112MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.91120997
113* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.90777773
114EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.90243580
115CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88812049
116FLI1_21867929_ChIP-Seq_TH2_Mouse0.88784076
117TCF4_22108803_ChIP-Seq_LS180_Human0.88712933
118ELK4_26923725_Chip-Seq_MESODERM_Mouse0.88497804
119KDM2B_26808549_Chip-Seq_JURKAT_Human0.88382210
120* SMC4_20622854_ChIP-Seq_HELA_Human0.88116048
121MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.87471905
122TCF4_23295773_ChIP-Seq_U87_Human0.87311550
123POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.87078342
124TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87078342
125AHR_22903824_ChIP-Seq_MCF-7_Human0.86934872
126EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.86682048
127* ZFP281_27345836_Chip-Seq_ESCs_Mouse0.86595015
128TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.85866296
129ARNT_22903824_ChIP-Seq_MCF-7_Human0.85439989
130KDM2B_26808549_Chip-Seq_SUP-B15_Human0.82814739
131PRDM14_20953172_ChIP-Seq_ESCs_Human0.80807973
132CREB1_26743006_Chip-Seq_LNCaP_Human0.80478716
133SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.80431672

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003011_delayed_dark_adaptation5.97839380
2MP0005551_abnormal_eye_electrophysiolog5.96018439
3MP0004859_abnormal_synaptic_plasticity4.32018459
4MP0006072_abnormal_retinal_apoptosis4.26817853
5MP0005253_abnormal_eye_physiology4.10660374
6MP0005423_abnormal_somatic_nervous3.74687261
7MP0003880_abnormal_central_pattern3.50123706
8MP0004270_analgesia3.17611880
9MP0003635_abnormal_synaptic_transmissio2.95585354
10MP0005195_abnormal_posterior_eye2.46440032
11MP0002638_abnormal_pupillary_reflex2.34181509
12MP0002063_abnormal_learning/memory/cond2.30884289
13MP0009046_muscle_twitch2.28433920
14MP0002734_abnormal_mechanical_nocicepti2.25514119
15MP0002229_neurodegeneration2.24061413
16MP0002064_seizures2.19572047
17MP0001968_abnormal_touch/_nociception2.18604653
18MP0009745_abnormal_behavioral_response2.17424962
19MP0001486_abnormal_startle_reflex2.05902782
20MP0002272_abnormal_nervous_system2.03243663
21MP0008877_abnormal_DNA_methylation2.00435963
22MP0001324_abnormal_eye_pigmentation1.97852265
23MP0002090_abnormal_vision1.90078046
24MP0002882_abnormal_neuron_morphology1.88903730
25MP0002572_abnormal_emotion/affect_behav1.87511473
26MP0005391_vision/eye_phenotype1.85233451
27MP0002752_abnormal_somatic_nervous1.80170579
28MP0002653_abnormal_ependyma_morphology1.80077891
29MP0002184_abnormal_innervation1.74445496
30MP0002735_abnormal_chemical_nociception1.72087679
31MP0000778_abnormal_nervous_system1.68766994
32MP0001502_abnormal_circadian_rhythm1.67655807
33MP0002067_abnormal_sensory_capabilities1.63683529
34MP0004885_abnormal_endolymph1.60763348
35MP0002733_abnormal_thermal_nociception1.54361805
36MP0006276_abnormal_autonomic_nervous1.54035245
37MP0001984_abnormal_olfaction1.48766130
38MP0001970_abnormal_pain_threshold1.47279442
39MP0001440_abnormal_grooming_behavior1.46892296
40MP0008569_lethality_at_weaning1.45834644
41MP0004811_abnormal_neuron_physiology1.41705320
42MP0002736_abnormal_nociception_after1.41161998
43MP0001188_hyperpigmentation1.34525071
44MP0000955_abnormal_spinal_cord1.32915946
45MP0003950_abnormal_plasma_membrane1.30296952
46MP0004924_abnormal_behavior1.30139162
47MP0005386_behavior/neurological_phenoty1.30139162
48MP0004145_abnormal_muscle_electrophysio1.29793503
49MP0004858_abnormal_nervous_system1.28299443
50MP0001986_abnormal_taste_sensitivity1.27826158
51MP0001485_abnormal_pinna_reflex1.27675212
52MP0002557_abnormal_social/conspecific_i1.26979784
53MP0003329_amyloid_beta_deposits1.22550812
54MP0002909_abnormal_adrenal_gland1.21966287
55MP0006292_abnormal_olfactory_placode1.21664278
56MP0001501_abnormal_sleep_pattern1.21503419
57MP0005499_abnormal_olfactory_system1.20767309
58MP0005394_taste/olfaction_phenotype1.20767309
59MP0003136_yellow_coat_color1.18391332
60MP0003879_abnormal_hair_cell1.17897055
61MP0004233_abnormal_muscle_weight1.16852330
62MP0003121_genomic_imprinting1.15603898
63MP0000751_myopathy1.13646527
64MP0009780_abnormal_chondrocyte_physiolo1.11962875
65MP0004133_heterotaxia1.11582855
66MP0002066_abnormal_motor_capabilities/c1.11536827
67MP0002751_abnormal_autonomic_nervous1.03448469
68MP0002152_abnormal_brain_morphology1.01467136
69MP0004742_abnormal_vestibular_system1.00589045
70MP0004142_abnormal_muscle_tone1.00047570
71MP0003634_abnormal_glial_cell0.98412163
72MP0005187_abnormal_penis_morphology0.96755459
73MP0002876_abnormal_thyroid_physiology0.91921055
74MP0002822_catalepsy0.91047412
75MP0003938_abnormal_ear_development0.87757333
76MP0004147_increased_porphyrin_level0.87525562
77MP0003633_abnormal_nervous_system0.86934131
78MP0008789_abnormal_olfactory_epithelium0.81345462
79MP0004215_abnormal_myocardial_fiber0.80043219
80MP0008961_abnormal_basal_metabolism0.79826287
81MP0001963_abnormal_hearing_physiology0.79642289
82MP0000013_abnormal_adipose_tissue0.78855793
83MP0003646_muscle_fatigue0.78572696
84MP0000569_abnormal_digit_pigmentation0.78536355
85MP0001177_atelectasis0.77278441
86MP0003119_abnormal_digestive_system0.75730633
87MP0003631_nervous_system_phenotype0.74637741
88MP0004085_abnormal_heartbeat0.74532964
89MP0002234_abnormal_pharynx_morphology0.73919431
90MP0001905_abnormal_dopamine_level0.73869988
91MP0005167_abnormal_blood-brain_barrier0.72444083
92MP0010386_abnormal_urinary_bladder0.71204855
93MP0002069_abnormal_eating/drinking_beha0.70940247
94MP0004043_abnormal_pH_regulation0.70606927
95MP0003698_abnormal_male_reproductive0.70450248
96MP0005377_hearing/vestibular/ear_phenot0.70247921
97MP0003878_abnormal_ear_physiology0.70247921
98MP0003787_abnormal_imprinting0.70098908
99MP0000631_abnormal_neuroendocrine_gland0.68792824
100MP0003122_maternal_imprinting0.67778199
101MP0005410_abnormal_fertilization0.67153265
102MP0003137_abnormal_impulse_conducting0.66122533
103MP0002928_abnormal_bile_duct0.66096371
104MP0003861_abnormal_nervous_system0.66092713
105MP0002938_white_spotting0.66004272
106MP0005646_abnormal_pituitary_gland0.65422728
107MP0005645_abnormal_hypothalamus_physiol0.65190786
108MP0002837_dystrophic_cardiac_calcinosis0.61271675
109MP0002102_abnormal_ear_morphology0.60627726
110MP0003632_abnormal_nervous_system0.59290837
111MP0001529_abnormal_vocalization0.58771749
112MP0003283_abnormal_digestive_organ0.54768952
113MP0002332_abnormal_exercise_endurance0.54254831
114MP0001764_abnormal_homeostasis0.52641176
115MP0005620_abnormal_muscle_contractility0.51460231
116MP0001299_abnormal_eye_distance/0.50760547
117MP0005197_abnormal_uvea_morphology0.49910813
118MP0008872_abnormal_physiological_respon0.49528029
119MP0002127_abnormal_cardiovascular_syste0.49388289
120MP0004130_abnormal_muscle_cell0.49291899
121MP0000026_abnormal_inner_ear0.48892948

Predicted human phenotypes

RankGene SetZ-score
1Absent rod-and cone-mediated responses on ERG (HP:0007688)9.14142313
2Abnormal rod and cone electroretinograms (HP:0008323)8.44423201
3Bony spicule pigmentary retinopathy (HP:0007737)8.24597766
4Central scotoma (HP:0000603)7.55341059
5Pendular nystagmus (HP:0012043)6.68443021
6Chorioretinal atrophy (HP:0000533)6.33652297
7Pigmentary retinal degeneration (HP:0001146)6.25559910
8Scotoma (HP:0000575)6.19046757
9Abnormality of macular pigmentation (HP:0008002)6.04524557
10Decreased central vision (HP:0007663)5.76823706
11Abolished electroretinogram (ERG) (HP:0000550)5.66382722
12Attenuation of retinal blood vessels (HP:0007843)5.29898557
13Dyschromatopsia (HP:0007641)5.13878581
14Severe visual impairment (HP:0001141)4.98817845
15Increased corneal curvature (HP:0100692)4.34616831
16Keratoconus (HP:0000563)4.34616831
17Type II diabetes mellitus (HP:0005978)4.33435236
18Posterior subcapsular cataract (HP:0007787)4.33189243
19Macular degeneration (HP:0000608)4.32249329
20Photophobia (HP:0000613)4.10853500
21Cone-rod dystrophy (HP:0000548)3.81499361
22Visual hallucinations (HP:0002367)3.74714200
23Myokymia (HP:0002411)3.56306787
24Constricted visual fields (HP:0001133)3.53288821
25Vitreoretinal degeneration (HP:0000655)3.46552843
26Choroideremia (HP:0001139)3.45489769
27Focal motor seizures (HP:0011153)3.31808232
28Retinitis pigmentosa (HP:0000510)3.18973615
29Decreased electroretinogram (ERG) amplitude (HP:0000654)3.04986016
30Hyperventilation (HP:0002883)3.03453728
31Progressive cerebellar ataxia (HP:0002073)3.02141662
32Epileptic encephalopathy (HP:0200134)2.97177169
33Focal seizures (HP:0007359)2.93552847
34Febrile seizures (HP:0002373)2.86927703
35Type II lissencephaly (HP:0007260)2.85293441
36Polyphagia (HP:0002591)2.79581293
37Pancreatic cysts (HP:0001737)2.78968354
38Nephronophthisis (HP:0000090)2.70382327
39Lissencephaly (HP:0001339)2.65089644
40Supranuclear gaze palsy (HP:0000605)2.60444402
41Abnormality of the labia minora (HP:0012880)2.58976337
42Subcapsular cataract (HP:0000523)2.50497774
43Hypsarrhythmia (HP:0002521)2.49078868
44Molar tooth sign on MRI (HP:0002419)2.48767059
45Abnormality of midbrain morphology (HP:0002418)2.48767059
46Progressive visual loss (HP:0000529)2.46059262
47Action tremor (HP:0002345)2.40432507
48Retinal dysplasia (HP:0007973)2.38198394
49Abnormality of binocular vision (HP:0011514)2.29782422
50Diplopia (HP:0000651)2.29782422
51Mutism (HP:0002300)2.26420002
52Abnormality of the renal medulla (HP:0100957)2.25409588
53Gait imbalance (HP:0002141)2.24880063
54Optic nerve hypoplasia (HP:0000609)2.23862201
55Inability to walk (HP:0002540)2.23565089
56Abnormality of the lower motor neuron (HP:0002366)2.23345668
57Pachygyria (HP:0001302)2.18915556
58Absent speech (HP:0001344)2.16772471
59Absence seizures (HP:0002121)2.15722193
60Torticollis (HP:0000473)2.11308724
61Dysdiadochokinesis (HP:0002075)2.10920177
62Status epilepticus (HP:0002133)2.10308764
63Abnormal drinking behavior (HP:0030082)2.09867285
64Polydipsia (HP:0001959)2.09867285
65Genetic anticipation (HP:0003743)2.09166181
66Atonic seizures (HP:0010819)2.08956687
67Broad-based gait (HP:0002136)2.08755016
68Cystic liver disease (HP:0006706)2.06567525
69Truncal ataxia (HP:0002078)2.05648203
70Wide nasal bridge (HP:0000431)2.04947197
71Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.00164094
72Congenital stationary night blindness (HP:0007642)10.5454691
73Morphological abnormality of the pyramidal tract (HP:0002062)1.99250047
74Optic disc pallor (HP:0000543)1.99170926
75Abnormality of the renal cortex (HP:0011035)1.97576320
76Ankle clonus (HP:0011448)1.96591290
77Spastic tetraplegia (HP:0002510)1.94278059
78Generalized tonic-clonic seizures (HP:0002069)1.91443127
79Amblyopia (HP:0000646)1.91189072
80Depression (HP:0000716)1.90792598
81Retinal atrophy (HP:0001105)1.90515710
82Intestinal atresia (HP:0011100)1.87931088
83Congenital primary aphakia (HP:0007707)1.87776104
84Protruding tongue (HP:0010808)1.87304455
85Dialeptic seizures (HP:0011146)1.86449672
86Sleep apnea (HP:0010535)1.85561301
87Gaze-evoked nystagmus (HP:0000640)1.83574303
88Focal dystonia (HP:0004373)1.83052905
89Cerebral hypomyelination (HP:0006808)1.81989929
90Spastic tetraparesis (HP:0001285)1.80124398
91Poor eye contact (HP:0000817)1.79229962
92Horizontal nystagmus (HP:0000666)1.79195453
93Dyskinesia (HP:0100660)1.78291556
94Urinary bladder sphincter dysfunction (HP:0002839)1.77603693
95Sclerocornea (HP:0000647)1.77449104
96Aplasia/Hypoplasia of the brainstem (HP:0007362)1.77431796
97Hypoplasia of the brainstem (HP:0002365)1.77431796
98Megalencephaly (HP:0001355)1.76287883
99Tubular atrophy (HP:0000092)1.75934350
100Chronic hepatic failure (HP:0100626)1.75057374
101Drooling (HP:0002307)1.72698354
102Excessive salivation (HP:0003781)1.72698354
103Oligodactyly (hands) (HP:0001180)1.71516119
104Patellar aplasia (HP:0006443)1.71273915
105Progressive inability to walk (HP:0002505)1.70551504
106Insomnia (HP:0100785)1.70508517
107Cerebellar dysplasia (HP:0007033)1.70273160
108Abnormal social behavior (HP:0012433)1.69464023
109Impaired social interactions (HP:0000735)1.69464023
110Congenital sensorineural hearing impairment (HP:0008527)1.68565892
111Anencephaly (HP:0002323)1.67918384
112Aqueductal stenosis (HP:0002410)1.65630654
113Ventricular fibrillation (HP:0001663)1.65591502
114Postural instability (HP:0002172)1.64213525
115Nephrogenic diabetes insipidus (HP:0009806)1.63949421
116Annular pancreas (HP:0001734)1.60972088
117Anxiety (HP:0000739)1.60373468
118Akinesia (HP:0002304)1.60236155
119Anophthalmia (HP:0000528)1.59996999
120Hemiparesis (HP:0001269)1.58575498
121Medial flaring of the eyebrow (HP:0010747)1.55979168
122Pheochromocytoma (HP:0002666)1.54238826
123Spastic gait (HP:0002064)1.54044390
124Impaired smooth pursuit (HP:0007772)1.53823891
125Specific learning disability (HP:0001328)1.52776334
126Dysmetria (HP:0001310)1.51103988
127Hypoventilation (HP:0002791)1.50239519
128Impaired vibration sensation in the lower limbs (HP:0002166)1.49301492
129Abnormality of ocular smooth pursuit (HP:0000617)1.47298092
130Abnormal eating behavior (HP:0100738)1.45463030
131Abnormality of the corticospinal tract (HP:0002492)1.43216407
132Urinary urgency (HP:0000012)1.43113656
133Prolonged QT interval (HP:0001657)1.42884603
134Vaginal atresia (HP:0000148)1.42817256
135Bradykinesia (HP:0002067)1.42804772
136Amyotrophic lateral sclerosis (HP:0007354)1.42316419
137Pancreatic fibrosis (HP:0100732)1.40879788
138True hermaphroditism (HP:0010459)1.40825119
139Polar cataract (HP:0010696)1.40416831
140Genital tract atresia (HP:0001827)1.40072431
141EEG with generalized epileptiform discharges (HP:0011198)1.37555404
142Agitation (HP:0000713)1.37369704
143Epileptiform EEG discharges (HP:0011182)1.37365825
144Poor coordination (HP:0002370)1.37055260
145Hemiplegia (HP:0002301)1.37030387
146Abnormal EKG (HP:0003115)1.36013788
147Intention tremor (HP:0002080)1.35542011
148Optic atrophy (HP:0000648)1.35341465
149Limb dystonia (HP:0002451)1.34450626

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.64035117
2GRK13.76557240
3NTRK33.36403204
4MAP3K93.28162563
5MAP3K42.75341312
6MINK12.70787581
7FRK2.54696375
8PAK62.53290884
9SIK22.15928488
10NTRK22.14802651
11MAP4K22.08834032
12PNCK2.08411880
13MAP2K72.01668673
14PINK11.96103027
15PHKG11.92605911
16PHKG21.92605911
17EPHA41.89107093
18BMPR1B1.82770115
19ADRBK21.82328721
20WNK31.81208366
21CAMKK11.74754670
22GRK51.73594369
23PRKD31.68691567
24MAP2K41.67006627
25DAPK21.62340850
26MAPK131.53451390
27STK381.52840919
28IRAK21.47395437
29CAMK1G1.46320019
30CDK51.40853259
31KSR11.36603227
32KSR21.28114729
33WNK41.27201866
34LATS21.26179017
35PLK21.24294367
36INSRR1.18253996
37OXSR11.18036944
38ICK1.13245269
39UHMK11.12957252
40TAOK11.10209502
41TRIM281.09329846
42PRKCG1.08218819
43CASK1.07212446
44SGK2231.06711983
45SGK4941.06711983
46MAP3K121.04906060
47DYRK1A1.03708374
48BCR0.97650250
49NEK10.96681988
50NTRK10.96302148
51TYRO30.95354271
52MARK20.94617745
53CAMKK20.94062444
54PRKCH0.92926938
55STK110.92645194
56NUAK10.91390391
57LMTK20.89301284
58CAMK10.88653916
59PRPF4B0.85714992
60CDK180.85177742
61CDK150.83070050
62PRKCE0.82845221
63PRKCZ0.81499955
64RET0.81346231
65TNIK0.81346080
66WNK10.79653092
67MAPK120.78907793
68CDK140.77517792
69DYRK20.76097322
70RIPK10.75899027
71ERBB20.75323464
72MAP3K100.74175761
73ALK0.73561316
74CDK11A0.73546575
75CSNK1G20.73129167
76MAP3K20.72647501
77CAMK2A0.71184979
78SGK20.70657014
79PAK30.69792461
80NME10.68389107
81SIK30.67463902
82CSNK1G30.67118670
83CDC42BPA0.66290468
84CAMK2B0.66138603
85DAPK10.65616623
86STK390.65112276
87PRKAA10.64251131
88CAMK1D0.63429984
89TAOK30.61636896
90ADRBK10.60906612
91CAMK40.60363650
92SGK10.60040461
93FES0.60035589
94SGK30.60003577
95ACVR1B0.59533853
96LIMK10.58308991
97RPS6KA30.57861717
98CDK190.57154838
99CSNK1A1L0.56839425
100SCYL20.56236963
101RPS6KA20.55867322
102PKN10.55102724
103CSNK1G10.54094697
104BRSK10.53930245
105MKNK20.53713703
106HIPK20.52817842
107ERBB30.51397781
108MAP2K60.51226146
109PRKCB0.50103898
110ZAK0.49600094
111PRKACA0.49268815
112MAPK150.48222009
113MAPK100.47666596
114CSNK1A10.47050272
115PRKG10.46176931
116PRKD20.45436272
117MAP3K70.45235034
118CSNK1D0.44586668
119MAPK90.44384456
120CSNK1E0.40958322
121FGFR20.40639967
122PRKACG0.40125573
123PLK40.39734617
124CAMK2D0.39616699
125GSK3B0.38698317
126PRKCA0.38617410
127MAPK80.38182008
128TXK0.37915040
129CAMK2G0.37784329
130FYN0.36573551
131BCKDK0.35119210
132MAPKAPK50.33631697
133TLK10.31316609

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047449.53261879
2Synaptic vesicle cycle_Homo sapiens_hsa047213.28156676
3Nicotine addiction_Homo sapiens_hsa050332.67407138
4GABAergic synapse_Homo sapiens_hsa047272.42308850
5Olfactory transduction_Homo sapiens_hsa047402.39216739
6Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.21014475
7Circadian entrainment_Homo sapiens_hsa047132.16132666
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.15600905
9Glutamatergic synapse_Homo sapiens_hsa047242.12994614
10Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.08115895
11Morphine addiction_Homo sapiens_hsa050321.93229973
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.82016943
13Dopaminergic synapse_Homo sapiens_hsa047281.81514626
14Cholinergic synapse_Homo sapiens_hsa047251.77322824
15Long-term potentiation_Homo sapiens_hsa047201.72917218
16Butanoate metabolism_Homo sapiens_hsa006501.70294261
17Insulin secretion_Homo sapiens_hsa049111.66261527
18Oxidative phosphorylation_Homo sapiens_hsa001901.53374143
19Salivary secretion_Homo sapiens_hsa049701.48246169
20Amphetamine addiction_Homo sapiens_hsa050311.47275315
21Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.46227301
22Aldosterone synthesis and secretion_Homo sapiens_hsa049251.43082074
23Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.42651164
24Oxytocin signaling pathway_Homo sapiens_hsa049211.36939345
25Serotonergic synapse_Homo sapiens_hsa047261.30773921
26Gastric acid secretion_Homo sapiens_hsa049711.30528367
27Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.26620769
28Parkinsons disease_Homo sapiens_hsa050121.24505621
29Cardiac muscle contraction_Homo sapiens_hsa042601.23294791
30Linoleic acid metabolism_Homo sapiens_hsa005911.23155054
31Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.23099144
32Taste transduction_Homo sapiens_hsa047421.22614678
33alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.21501666
34Maturity onset diabetes of the young_Homo sapiens_hsa049501.15749210
35Cocaine addiction_Homo sapiens_hsa050301.15072546
36Renin secretion_Homo sapiens_hsa049241.13775358
37Ether lipid metabolism_Homo sapiens_hsa005651.08424499
38Long-term depression_Homo sapiens_hsa047301.07577868
39GnRH signaling pathway_Homo sapiens_hsa049121.04171840
40Type II diabetes mellitus_Homo sapiens_hsa049301.04165520
41Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.03992750
42Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.01172885
43cGMP-PKG signaling pathway_Homo sapiens_hsa040220.98844273
44Calcium signaling pathway_Homo sapiens_hsa040200.98780436
45cAMP signaling pathway_Homo sapiens_hsa040240.98712850
46Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.97584158
47Axon guidance_Homo sapiens_hsa043600.95479556
48Circadian rhythm_Homo sapiens_hsa047100.93904291
49Phosphatidylinositol signaling system_Homo sapiens_hsa040700.93169592
50Gap junction_Homo sapiens_hsa045400.93156188
51Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.87224442
52Nitrogen metabolism_Homo sapiens_hsa009100.85077448
53Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.85048129
54Collecting duct acid secretion_Homo sapiens_hsa049660.84338477
55Huntingtons disease_Homo sapiens_hsa050160.80676398
56Dilated cardiomyopathy_Homo sapiens_hsa054140.80196398
57Glioma_Homo sapiens_hsa052140.79994336
58Carbohydrate digestion and absorption_Homo sapiens_hsa049730.79397026
59ErbB signaling pathway_Homo sapiens_hsa040120.73478908
60Estrogen signaling pathway_Homo sapiens_hsa049150.73465039
61mTOR signaling pathway_Homo sapiens_hsa041500.73383207
62Tryptophan metabolism_Homo sapiens_hsa003800.71818359
63Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.70025325
64Thyroid hormone signaling pathway_Homo sapiens_hsa049190.69390569
65Melanogenesis_Homo sapiens_hsa049160.68857061
66Protein export_Homo sapiens_hsa030600.68358350
67Oocyte meiosis_Homo sapiens_hsa041140.68215032
68Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.67959811
69Vitamin B6 metabolism_Homo sapiens_hsa007500.65208623
70Ovarian steroidogenesis_Homo sapiens_hsa049130.65089391
71Hedgehog signaling pathway_Homo sapiens_hsa043400.65019173
72Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.63662880
73Regulation of autophagy_Homo sapiens_hsa041400.62331448
74Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.62172488
75Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.61183119
76Phospholipase D signaling pathway_Homo sapiens_hsa040720.59637795
77Vascular smooth muscle contraction_Homo sapiens_hsa042700.59457695
78Selenocompound metabolism_Homo sapiens_hsa004500.58196152
79Pancreatic secretion_Homo sapiens_hsa049720.58021128
80Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.57366150
81Basal transcription factors_Homo sapiens_hsa030220.57110466
82Glucagon signaling pathway_Homo sapiens_hsa049220.57034677
83MAPK signaling pathway_Homo sapiens_hsa040100.55583299
84ABC transporters_Homo sapiens_hsa020100.55536533
85Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.55051545
86Choline metabolism in cancer_Homo sapiens_hsa052310.54793269
87Vibrio cholerae infection_Homo sapiens_hsa051100.54545950
88beta-Alanine metabolism_Homo sapiens_hsa004100.54349071
89Inositol phosphate metabolism_Homo sapiens_hsa005620.53277004
90Longevity regulating pathway - mammal_Homo sapiens_hsa042110.53053745
91Endometrial cancer_Homo sapiens_hsa052130.50806440
92Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.50396350
93Thyroid hormone synthesis_Homo sapiens_hsa049180.50042505
94Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.49096720
95Propanoate metabolism_Homo sapiens_hsa006400.48624480
96Insulin signaling pathway_Homo sapiens_hsa049100.48302242
97Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.48158340
98VEGF signaling pathway_Homo sapiens_hsa043700.47069431
99Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.45430428
100Neurotrophin signaling pathway_Homo sapiens_hsa047220.44769653
101Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.44746273
102SNARE interactions in vesicular transport_Homo sapiens_hsa041300.44738891
103Hippo signaling pathway_Homo sapiens_hsa043900.44232960
104RNA polymerase_Homo sapiens_hsa030200.43583869
105Central carbon metabolism in cancer_Homo sapiens_hsa052300.43400841
106Ras signaling pathway_Homo sapiens_hsa040140.42793558
107Renal cell carcinoma_Homo sapiens_hsa052110.42227579
108Alcoholism_Homo sapiens_hsa050340.41009650
109Bile secretion_Homo sapiens_hsa049760.39888190
110Dorso-ventral axis formation_Homo sapiens_hsa043200.39393724
111Arginine and proline metabolism_Homo sapiens_hsa003300.38982708
112Basal cell carcinoma_Homo sapiens_hsa052170.38721437
113Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.36876968
114Endocytosis_Homo sapiens_hsa041440.36463765
115Peroxisome_Homo sapiens_hsa041460.35837529
116AMPK signaling pathway_Homo sapiens_hsa041520.35587524
117Fanconi anemia pathway_Homo sapiens_hsa034600.35387271
118Caffeine metabolism_Homo sapiens_hsa002320.34590443
119Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.34525668
120Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.34425705
121Wnt signaling pathway_Homo sapiens_hsa043100.34362637
122Glycerolipid metabolism_Homo sapiens_hsa005610.31888251
123Glycerophospholipid metabolism_Homo sapiens_hsa005640.30082137
124Steroid biosynthesis_Homo sapiens_hsa001000.29557495
125Non-small cell lung cancer_Homo sapiens_hsa052230.28737209
126Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.27478018
127Fatty acid biosynthesis_Homo sapiens_hsa000610.27045271
128Rap1 signaling pathway_Homo sapiens_hsa040150.26446968
129Sphingolipid signaling pathway_Homo sapiens_hsa040710.26440875
130Colorectal cancer_Homo sapiens_hsa052100.25482374
131Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.25344568
132Tight junction_Homo sapiens_hsa045300.23879027
133Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.22085249
134HIF-1 signaling pathway_Homo sapiens_hsa040660.21821916
135Alzheimers disease_Homo sapiens_hsa050100.20415642
136Prion diseases_Homo sapiens_hsa050200.20325300
137Chemokine signaling pathway_Homo sapiens_hsa040620.20163978
138Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.19295801

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