FAM208A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)4.59456763
2monoubiquitinated protein deubiquitination (GO:0035520)4.54744101
3DNA topological change (GO:0006265)4.36779462
4regulation of protein polyubiquitination (GO:1902914)4.33378558
5negative regulation of translation, ncRNA-mediated (GO:0040033)4.25042780
6regulation of translation, ncRNA-mediated (GO:0045974)4.25042780
7negative regulation of translation involved in gene silencing by miRNA (GO:0035278)4.25042780
8mitotic sister chromatid cohesion (GO:0007064)4.18694505
9histone H3-K4 trimethylation (GO:0080182)4.08071403
10positive regulation of mitotic metaphase/anaphase transition (GO:0045842)4.01540274
11positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)4.01540274
12positive regulation of mitotic sister chromatid separation (GO:1901970)4.01540274
13nuclear pore organization (GO:0006999)3.95011460
14DNA double-strand break processing (GO:0000729)3.85228345
15regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.73392588
16negative regulation of histone methylation (GO:0031061)3.72531760
17regulation of histone H3-K9 methylation (GO:0051570)3.69005209
18determination of adult lifespan (GO:0008340)3.64525050
19regulation of histone H3-K27 methylation (GO:0061085)3.61375888
20pericardium development (GO:0060039)3.60664757
21pore complex assembly (GO:0046931)3.53260827
22cytoplasmic mRNA processing body assembly (GO:0033962)3.51413547
23histone H3-K36 demethylation (GO:0070544)3.49257703
24phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.48042195
25histone lysine demethylation (GO:0070076)3.41761026
26neural tube formation (GO:0001841)3.37374876
27negative regulation of DNA-dependent DNA replication (GO:2000104)3.35815647
28histone-serine phosphorylation (GO:0035404)3.32034550
29regulation of establishment of cell polarity (GO:2000114)3.29739118
30peptidyl-lysine trimethylation (GO:0018023)3.27391157
31sister chromatid segregation (GO:0000819)3.25843270
32histone H3-K4 methylation (GO:0051568)3.20398763
33NLS-bearing protein import into nucleus (GO:0006607)3.20398170
34histone demethylation (GO:0016577)3.20396301
35regulation of DNA endoreduplication (GO:0032875)3.17408990
36regulation of centrosome duplication (GO:0010824)3.11395276
37stress granule assembly (GO:0034063)3.09578491
38nucleus localization (GO:0051647)3.08619318
39cellular response to ethanol (GO:0071361)3.03695409
40centrosome duplication (GO:0051298)3.01866567
41establishment of nucleus localization (GO:0040023)3.00947509
42histone H3-K9 demethylation (GO:0033169)2.95170706
43positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.94917733
44regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.94917733
45regulation of helicase activity (GO:0051095)2.94397188
46protein K11-linked deubiquitination (GO:0035871)2.93858355
47embryonic process involved in female pregnancy (GO:0060136)2.93459076
48regulation of mRNA 3-end processing (GO:0031440)2.91620564
49hepatocyte apoptotic process (GO:0097284)2.90797771
50regulation of B cell receptor signaling pathway (GO:0050855)2.87336588
51regulation of centrosome cycle (GO:0046605)2.86954085
52regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.84987106
53regulation of pigment cell differentiation (GO:0050932)2.84916392
54establishment of chromosome localization (GO:0051303)2.84384987
55protein localization to chromosome, centromeric region (GO:0071459)2.82559777
56histone H3-K9 modification (GO:0061647)2.82552934
57replicative senescence (GO:0090399)2.80260605
58establishment of protein localization to Golgi (GO:0072600)2.79723765
59attachment of spindle microtubules to kinetochore (GO:0008608)2.79356442
60lipid translocation (GO:0034204)2.77495065
61phospholipid translocation (GO:0045332)2.77495065
62oocyte development (GO:0048599)2.77161555
63regulation of nuclear cell cycle DNA replication (GO:0033262)2.76961223
64histone lysine methylation (GO:0034968)2.76606845
65sister chromatid cohesion (GO:0007062)2.75974253
66regulation of sister chromatid cohesion (GO:0007063)2.75901084
67early endosome to late endosome transport (GO:0045022)2.75291721
68intra-S DNA damage checkpoint (GO:0031573)2.74484444
69regulation of Rac protein signal transduction (GO:0035020)2.73739107
70gene silencing by RNA (GO:0031047)2.73335277
71definitive hemopoiesis (GO:0060216)2.73281074
72positive regulation of cell cycle checkpoint (GO:1901978)2.72826184
73protein localization to kinetochore (GO:0034501)2.72702144
74mitotic nuclear envelope disassembly (GO:0007077)2.71262104
75nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.70720775
76non-recombinational repair (GO:0000726)2.69713298
77double-strand break repair via nonhomologous end joining (GO:0006303)2.69713298
78histone H3-K9 methylation (GO:0051567)2.69582358
79protein dealkylation (GO:0008214)2.69158745
80protein demethylation (GO:0006482)2.69158745
81replication fork processing (GO:0031297)2.68766919
82regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.68723279
83positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.68723279
84regulation of centriole replication (GO:0046599)2.68446373
85labyrinthine layer development (GO:0060711)2.67447014
86positive regulation of developmental pigmentation (GO:0048087)2.67197432
87regulation of telomere maintenance (GO:0032204)2.66538446
88microtubule anchoring (GO:0034453)2.66455048
89positive regulation of mRNA 3-end processing (GO:0031442)2.65911734
90centriole replication (GO:0007099)2.64884642
91DNA geometric change (GO:0032392)2.64781058
92membrane disassembly (GO:0030397)2.64289162
93nuclear envelope disassembly (GO:0051081)2.64289162
94V(D)J recombination (GO:0033151)2.64141376
95nucleus organization (GO:0006997)2.63052763
96mitotic chromosome condensation (GO:0007076)2.62341939
97regulation of gene silencing by miRNA (GO:0060964)2.62322673
98regulation of gene silencing by RNA (GO:0060966)2.62322673
99regulation of posttranscriptional gene silencing (GO:0060147)2.62322673
100regulation of histone methylation (GO:0031060)2.62062168
101resolution of meiotic recombination intermediates (GO:0000712)2.61914976
102epithelial cell maturation (GO:0002070)2.61468483
103positive regulation of granulocyte differentiation (GO:0030854)2.61180889
104DNA duplex unwinding (GO:0032508)2.60868757
105mitotic metaphase plate congression (GO:0007080)2.59868767
106peptidyl-threonine phosphorylation (GO:0018107)2.59295799
107RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.59130494
108regulation of fibroblast apoptotic process (GO:2000269)2.59018168
109L-amino acid import (GO:0043092)2.58080718
110negative regulation of fibroblast apoptotic process (GO:2000270)2.56783818
111regulation of establishment or maintenance of cell polarity (GO:0032878)2.56289876
112kinetochore organization (GO:0051383)2.56258732
113interkinetic nuclear migration (GO:0022027)2.55963365
114protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)2.55788209
115positive regulation of mRNA processing (GO:0050685)2.53668178
116protein K48-linked deubiquitination (GO:0071108)2.52939121
117positive regulation of histone methylation (GO:0031062)2.50723428
118mitotic sister chromatid segregation (GO:0000070)2.50500191
119presynaptic membrane assembly (GO:0097105)2.50203403
120protein prenylation (GO:0018342)2.50044573
121prenylation (GO:0097354)2.50044573
122photoreceptor cell differentiation (GO:0046530)2.49923266
123eye photoreceptor cell differentiation (GO:0001754)2.49923266
124positive regulation of mRNA catabolic process (GO:0061014)2.49422312
125DNA unwinding involved in DNA replication (GO:0006268)2.49391673
126peptidyl-threonine modification (GO:0018210)2.49088343
127meiotic chromosome segregation (GO:0045132)2.49084541
128pre-miRNA processing (GO:0031054)2.48981172
129synapsis (GO:0007129)2.48830064
130head development (GO:0060322)2.48499212
131Golgi to endosome transport (GO:0006895)2.48339572
132translesion synthesis (GO:0019985)2.48126620
133mitochondrial DNA replication (GO:0006264)2.47567323
134histone phosphorylation (GO:0016572)2.47521569
135regulation of mRNA catabolic process (GO:0061013)2.47309698
136regulation of RNA export from nucleus (GO:0046831)2.46807122
137regulation of nucleobase-containing compound transport (GO:0032239)2.46218441
138positive regulation of glycoprotein biosynthetic process (GO:0010560)2.45730213
139metaphase plate congression (GO:0051310)2.45582491
140negative regulation of neurotransmitter secretion (GO:0046929)2.45011150
141mRNA splice site selection (GO:0006376)2.44565795
142negative regulation of chromatin modification (GO:1903309)2.44155560
143histone H2A monoubiquitination (GO:0035518)2.44142535
144regulation of DNA methylation (GO:0044030)2.41343390
145genitalia morphogenesis (GO:0035112)2.41086644
146positive regulation of respiratory burst (GO:0060267)2.40284131
147regulation of gene silencing (GO:0060968)2.39883614
148glucocorticoid receptor signaling pathway (GO:0042921)2.38251773
149regulation of gene expression by genetic imprinting (GO:0006349)2.38011538
150histone mRNA catabolic process (GO:0071044)2.37993154
151positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043)2.37398078
152negative regulation of DNA recombination (GO:0045910)2.36572944
153regulation of chromatin silencing (GO:0031935)2.36251161
154cerebral cortex radially oriented cell migration (GO:0021799)2.36016434
155protein targeting to Golgi (GO:0000042)2.34016153
156negative regulation of Rho protein signal transduction (GO:0035024)2.34001871
157positive regulation of mRNA metabolic process (GO:1903313)2.33766905
158peptidyl-lysine methylation (GO:0018022)2.33264305
159negative regulation of DNA repair (GO:0045738)2.30642570
160pyrimidine dimer repair (GO:0006290)2.28850783
161acrosome assembly (GO:0001675)2.28017458
162central nervous system myelination (GO:0022010)2.26811104
163axon ensheathment in central nervous system (GO:0032291)2.26811104
164cilium or flagellum-dependent cell motility (GO:0001539)2.24964991
165positive regulation of gene expression, epigenetic (GO:0045815)2.21965518
166embryonic retina morphogenesis in camera-type eye (GO:0060059)2.21043505
167microtubule depolymerization (GO:0007019)2.20605461
168response to hepatocyte growth factor (GO:0035728)2.19846626
169cellular response to hepatocyte growth factor stimulus (GO:0035729)2.19846626
170prostate gland growth (GO:0060736)2.19756993

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse5.20182762
2SALL1_21062744_ChIP-ChIP_HESCs_Human4.05501182
3E2F7_22180533_ChIP-Seq_HELA_Human3.90683757
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.16112210
5CEBPD_23245923_ChIP-Seq_MEFs_Mouse3.00992181
6GBX2_23144817_ChIP-Seq_PC3_Human2.59778960
7POU3F2_20337985_ChIP-ChIP_501MEL_Human2.57477260
8KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.44420961
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.41507883
10SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.25917662
11ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.13913295
12RBPJ_22232070_ChIP-Seq_NCS_Mouse2.08724036
13FLI1_27457419_Chip-Seq_LIVER_Mouse2.08378197
14FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.02960519
15AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.02757162
16SMAD_19615063_ChIP-ChIP_OVARY_Human2.02673317
17FUS_26573619_Chip-Seq_HEK293_Human1.95455823
18IGF1R_20145208_ChIP-Seq_DFB_Human1.85309771
19EWS_26573619_Chip-Seq_HEK293_Human1.77766418
20TAF15_26573619_Chip-Seq_HEK293_Human1.75831854
21PIAS1_25552417_ChIP-Seq_VCAP_Human1.75617666
22HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.74035721
23GATA1_22025678_ChIP-Seq_K562_Human1.72224474
24TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.69197310
25STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.68162926
26ZFP57_27257070_Chip-Seq_ESCs_Mouse1.67782493
27IRF1_19129219_ChIP-ChIP_H3396_Human1.67566607
28PCGF2_27294783_Chip-Seq_ESCs_Mouse1.66258051
29NANOG_18555785_Chip-Seq_ESCs_Mouse1.65456184
30TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.65114529
31MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.64260269
32STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.63299312
33TP53_16413492_ChIP-PET_HCT116_Human1.62407240
34STAT3_23295773_ChIP-Seq_U87_Human1.61896525
35P300_19829295_ChIP-Seq_ESCs_Human1.59140977
36OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.57823517
37E2F4_17652178_ChIP-ChIP_JURKAT_Human1.57076238
38SMAD4_21799915_ChIP-Seq_A2780_Human1.55477169
39FOXM1_23109430_ChIP-Seq_U2OS_Human1.54786358
40PCGF2_27294783_Chip-Seq_NPCs_Mouse1.52398262
41E2F1_18555785_Chip-Seq_ESCs_Mouse1.51859174
42ARNT_22903824_ChIP-Seq_MCF-7_Human1.51731526
43CDX2_19796622_ChIP-Seq_MESCs_Mouse1.50166111
44POU5F1_16153702_ChIP-ChIP_HESCs_Human1.49846356
45NR3C1_21868756_ChIP-Seq_MCF10A_Human1.48676280
46SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.45179036
47TP63_19390658_ChIP-ChIP_HaCaT_Human1.43744807
48SUZ12_27294783_Chip-Seq_NPCs_Mouse1.43157284
49EGR1_19374776_ChIP-ChIP_THP-1_Human1.42344622
50SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.41646703
51TCF4_23295773_ChIP-Seq_U87_Human1.41141502
52AHR_22903824_ChIP-Seq_MCF-7_Human1.40949008
53WT1_19549856_ChIP-ChIP_CCG9911_Human1.40774980
54SMAD3_21741376_ChIP-Seq_EPCs_Human1.40421984
55ZNF217_24962896_ChIP-Seq_MCF-7_Human1.39089241
56NFE2_27457419_Chip-Seq_LIVER_Mouse1.38749232
57EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.38389235
58STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.36963742
59TCF4_18268006_ChIP-ChIP_LS174T_Human1.36637374
60SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.35981769
61CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.35382486
62SUZ12_18555785_Chip-Seq_ESCs_Mouse1.35351264
63CMYC_18555785_Chip-Seq_ESCs_Mouse1.33946294
64EZH2_27294783_Chip-Seq_NPCs_Mouse1.33325312
65MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.33116389
66PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.32288128
67HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.31862255
68AR_21909140_ChIP-Seq_LNCAP_Human1.30767793
69P53_22387025_ChIP-Seq_ESCs_Mouse1.30063861
70POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.29768391
71TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29768391
72GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29624948
73TCF3_18692474_ChIP-Seq_MESCs_Mouse1.29257324
74OCT4_18555785_Chip-Seq_ESCs_Mouse1.28738758
75P300_18555785_Chip-Seq_ESCs_Mouse1.28011126
76* BRD4_25478319_ChIP-Seq_HGPS_Human1.26994695
77ELK1_19687146_ChIP-ChIP_HELA_Human1.25236664
78PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.23175842
79SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.21823340
80TBX3_20139965_ChIP-Seq_MESCs_Mouse1.21245062
81TBX3_20139965_ChIP-Seq_ESCs_Mouse1.21229226
82DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.21140554
83VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.18312773
84AR_25329375_ChIP-Seq_VCAP_Human1.17213481
85AR_21572438_ChIP-Seq_LNCaP_Human1.17183226
86EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.16830838
87NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.16684272
88NRF2_20460467_ChIP-Seq_MEFs_Mouse1.16684272
89CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.16374692
90IRF8_22096565_ChIP-ChIP_GC-B_Human1.15622980
91FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.15187378
92RUNX1_27457419_Chip-Seq_LIVER_Mouse1.15063763
93SOX2_18555785_Chip-Seq_ESCs_Mouse1.14253855
94STAT3_18555785_Chip-Seq_ESCs_Mouse1.14127976
95RUNX_20019798_ChIP-Seq_JUKART_Human1.14070093
96PADI4_21655091_ChIP-ChIP_MCF-7_Human1.13984037
97SOX2_18555785_ChIP-Seq_MESCs_Mouse1.13378535
98FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.12458752
99CBP_20019798_ChIP-Seq_JUKART_Human1.12176702
100IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.12176702
101Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.12175125
102E2F1_21310950_ChIP-Seq_MCF-7_Human1.11857406
103TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.11782268
104FOXM1_26456572_ChIP-Seq_MCF-7_Human1.11661196
105BCAT_22108803_ChIP-Seq_LS180_Human1.11238618
106RUNX2_22187159_ChIP-Seq_PCA_Human1.10837107
107CTBP2_25329375_ChIP-Seq_LNCAP_Human1.10424498
108NMYC_18555785_Chip-Seq_ESCs_Mouse1.10070425
109ER_23166858_ChIP-Seq_MCF-7_Human1.09434972
110CTBP1_25329375_ChIP-Seq_LNCAP_Human1.08989174
111POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.08940315
112PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.07855532
113FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.07825013
114SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.06932889
115PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.06817206
116OCT4_21477851_ChIP-Seq_ESCs_Mouse1.05715928
117TOP2B_26459242_ChIP-Seq_MCF-7_Human1.04968012
118RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.04270127
119MYB_26560356_Chip-Seq_TH2_Human1.03860280
120CTNNB1_20460455_ChIP-Seq_HCT116_Human1.03266256
121SOX2_21211035_ChIP-Seq_LN229_Gbm1.03178224
122SALL4_18804426_ChIP-ChIP_XEN_Mouse1.03124977
123NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.02575932
124FLI1_21867929_ChIP-Seq_TH2_Mouse1.02484954
125RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.01530031
126CRX_20693478_ChIP-Seq_RETINA_Mouse0.99374675
127ESRRB_18555785_Chip-Seq_ESCs_Mouse0.98946352
128SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.98132557
129YAP1_20516196_ChIP-Seq_MESCs_Mouse0.97525913
130KDM2B_26808549_Chip-Seq_REH_Human0.97503802
131UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.97123624
132PU1_27457419_Chip-Seq_LIVER_Mouse0.96112899
133KLF4_18555785_Chip-Seq_ESCs_Mouse0.95845791

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.61246607
2MP0003787_abnormal_imprinting3.86490364
3MP0003890_abnormal_embryonic-extraembry3.52501297
4MP0002009_preneoplasia3.38518938
5MP0006054_spinal_hemorrhage2.69290219
6MP0003763_abnormal_thymus_physiology2.52438766
7MP0004885_abnormal_endolymph2.49385090
8MP0003950_abnormal_plasma_membrane2.48292889
9MP0010352_gastrointestinal_tract_polyps2.48083470
10MP0004270_analgesia2.46712300
11MP0003121_genomic_imprinting2.46444810
12MP0000569_abnormal_digit_pigmentation2.26592107
13MP0008877_abnormal_DNA_methylation2.08927980
14MP0010094_abnormal_chromosome_stability2.02826753
15MP0004264_abnormal_extraembryonic_tissu2.01308721
16MP0005379_endocrine/exocrine_gland_phen1.95625808
17MP0001661_extended_life_span1.93327396
18MP0003136_yellow_coat_color1.82505502
19MP0005171_absent_coat_pigmentation1.82066696
20MP0001177_atelectasis1.81974789
21MP0001486_abnormal_startle_reflex1.77254970
22MP0003943_abnormal_hepatobiliary_system1.76595431
23MP0003690_abnormal_glial_cell1.76229521
24MP0008058_abnormal_DNA_repair1.73483152
25MP0003937_abnormal_limbs/digits/tail_de1.71327474
26MP0004808_abnormal_hematopoietic_stem1.69245464
27MP0000566_synostosis1.68110742
28MP0004133_heterotaxia1.65706874
29MP0009703_decreased_birth_body1.63594378
30MP0006292_abnormal_olfactory_placode1.63501383
31MP0000778_abnormal_nervous_system1.61287160
32MP0002877_abnormal_melanocyte_morpholog1.55222382
33MP0002928_abnormal_bile_duct1.54135419
34MP0005248_abnormal_Harderian_gland1.53266381
35MP0010678_abnormal_skin_adnexa1.51604458
36MP0001485_abnormal_pinna_reflex1.51418384
37MP0001188_hyperpigmentation1.50643647
38MP0003111_abnormal_nucleus_morphology1.50030073
39MP0003300_gastrointestinal_ulcer1.46090687
40MP0006072_abnormal_retinal_apoptosis1.42906197
41MP0003941_abnormal_skin_development1.42592631
42MP0010234_abnormal_vibrissa_follicle1.39692606
43MP0005551_abnormal_eye_electrophysiolog1.37082556
44MP0001835_abnormal_antigen_presentation1.35552792
45MP0002396_abnormal_hematopoietic_system1.32805746
46MP0008007_abnormal_cellular_replicative1.32310716
47MP0005253_abnormal_eye_physiology1.32004801
48MP0002166_altered_tumor_susceptibility1.31446284
49MP0003221_abnormal_cardiomyocyte_apopto1.31061617
50MP0003252_abnormal_bile_duct1.31058577
51MP0003091_abnormal_cell_migration1.29303051
52MP0001286_abnormal_eye_development1.28415037
53MP0002254_reproductive_system_inflammat1.25298097
54MP0004147_increased_porphyrin_level1.24003880
55MP0001986_abnormal_taste_sensitivity1.23861684
56MP0005076_abnormal_cell_differentiation1.23258600
57MP0005174_abnormal_tail_pigmentation1.22237552
58MP0000703_abnormal_thymus_morphology1.21704664
59MP0004043_abnormal_pH_regulation1.21503335
60MP0000428_abnormal_craniofacial_morphol1.20432781
61MP0001293_anophthalmia1.19043969
62MP0003984_embryonic_growth_retardation1.16777020
63MP0000432_abnormal_head_morphology1.15972744
64MP0002088_abnormal_embryonic_growth/wei1.15714774
65MP0005670_abnormal_white_adipose1.14712922
66MP0005187_abnormal_penis_morphology1.13184644
67MP0004957_abnormal_blastocyst_morpholog1.12761320
68MP0003077_abnormal_cell_cycle1.12365647
69MP0003935_abnormal_craniofacial_develop1.09043372
70MP0004134_abnormal_chest_morphology1.07199588
71MP0001915_intracranial_hemorrhage1.06757083
72MP0010307_abnormal_tumor_latency1.04600480
73MP0002084_abnormal_developmental_patter1.03343578
74MP0005391_vision/eye_phenotype1.02829876
75MP0005647_abnormal_sex_gland1.02753889
76MP0003123_paternal_imprinting1.02726978
77MP0002006_tumorigenesis1.01048484
78MP0003632_abnormal_nervous_system0.98946689
79MP0001697_abnormal_embryo_size0.98229000
80MP0002086_abnormal_extraembryonic_tissu0.97040577
81MP0002398_abnormal_bone_marrow0.97005212
82MP0001730_embryonic_growth_arrest0.96439353
83MP0005409_darkened_coat_color0.96200755
84MP0000383_abnormal_hair_follicle0.95648623
85MP0000371_diluted_coat_color0.94945244
86MP0002075_abnormal_coat/hair_pigmentati0.94417892
87MP0000465_gastrointestinal_hemorrhage0.94307620
88MP0000427_abnormal_hair_cycle0.93904874
89MP0001186_pigmentation_phenotype0.93702155
90MP0003936_abnormal_reproductive_system0.93515653
91MP0001929_abnormal_gametogenesis0.92805785
92MP0003045_fibrosis0.91910356
93MP0002168_other_aberrant_phenotype0.91595294
94MP0003698_abnormal_male_reproductive0.91067956
95MP0004084_abnormal_cardiac_muscle0.90462243
96MP0003868_abnormal_feces_composition0.90031583
97MP0001672_abnormal_embryogenesis/_devel0.89765058
98MP0005380_embryogenesis_phenotype0.89765058
99MP0001919_abnormal_reproductive_system0.88417491
100MP0003861_abnormal_nervous_system0.88310844
101MP0003656_abnormal_erythrocyte_physiolo0.88038208
102MP0000462_abnormal_digestive_system0.87858559
103MP0005621_abnormal_cell_physiology0.87481659
104MP0002138_abnormal_hepatobiliary_system0.87457945
105MP0009780_abnormal_chondrocyte_physiolo0.86316785
106MP0001800_abnormal_humoral_immune0.85554996
107MP0001879_abnormal_lymphatic_vessel0.85316496
108MP0003183_abnormal_peptide_metabolism0.85095304
109MP0004381_abnormal_hair_follicle0.84325975
110MP0002210_abnormal_sex_determination0.83722511
111MP0005646_abnormal_pituitary_gland0.83573375
112MP0000685_abnormal_immune_system0.83412933
113MP0001963_abnormal_hearing_physiology0.83153938
114MP0005195_abnormal_posterior_eye0.82872844
115MP0005623_abnormal_meninges_morphology0.82853961
116MP0004197_abnormal_fetal_growth/weight/0.82735969
117MP0002233_abnormal_nose_morphology0.82241219
118MP0000689_abnormal_spleen_morphology0.82094177
119MP0000613_abnormal_salivary_gland0.81428389
120MP0009672_abnormal_birth_weight0.80234868
121MP0005389_reproductive_system_phenotype0.80026845
122MP0000627_abnormal_mammary_gland0.79755627
123MP0000015_abnormal_ear_pigmentation0.78918344
124MP0000516_abnormal_urinary_system0.78734285
125MP0005367_renal/urinary_system_phenotyp0.78734285
126MP0005408_hypopigmentation0.78174239
127MP0005395_other_phenotype0.77730042
128MP0000350_abnormal_cell_proliferation0.75380339
129MP0009384_cardiac_valve_regurgitation0.75173562
130MP0002234_abnormal_pharynx_morphology0.74637112
131MP0002092_abnormal_eye_morphology0.74561532
132MP0001784_abnormal_fluid_regulation0.74561476
133MP0000537_abnormal_urethra_morphology0.74304020
134MP0001119_abnormal_female_reproductive0.74256425
135MP0005075_abnormal_melanosome_morpholog0.74096177
136MP0009697_abnormal_copulation0.73080879
137MP0002085_abnormal_embryonic_tissue0.72746058
138MP0005220_abnormal_exocrine_pancreas0.72656747
139MP0002152_abnormal_brain_morphology0.72230981
140MP0005310_abnormal_salivary_gland0.72216433
141MP0002229_neurodegeneration0.72003664
142MP0000631_abnormal_neuroendocrine_gland0.71801473
143MP0002697_abnormal_eye_size0.71019948
144MP0000733_abnormal_muscle_development0.69877654
145MP0002722_abnormal_immune_system0.69464140
146MP0003693_abnormal_embryo_hatching0.69319592
147MP0002019_abnormal_tumor_incidence0.68796049
148MP0005384_cellular_phenotype0.68793135
149MP0002095_abnormal_skin_pigmentation0.68527272
150MP0003828_pulmonary_edema0.67505660

Predicted human phenotypes

RankGene SetZ-score
1Chronic hepatic failure (HP:0100626)3.35436591
2Volvulus (HP:0002580)3.16460181
3Chromsome breakage (HP:0040012)3.05826995
4T lymphocytopenia (HP:0005403)3.05495348
5Chromosomal breakage induced by crosslinking agents (HP:0003221)2.93902751
6Thyroiditis (HP:0100646)2.85681854
7Subacute progressive viral hepatitis (HP:0006572)2.84564619
8Papillary thyroid carcinoma (HP:0002895)2.83302975
9Abnormality of the fingertips (HP:0001211)2.81191169
10Acute myeloid leukemia (HP:0004808)2.74129967
11Fair hair (HP:0002286)2.71128931
12Abnormality of T cell number (HP:0011839)2.70256877
13Protruding tongue (HP:0010808)2.66399377
14Thyroid carcinoma (HP:0002890)2.66364748
15Astrocytoma (HP:0009592)2.64688906
16Abnormality of the astrocytes (HP:0100707)2.64688906
17Neoplasm of the adrenal cortex (HP:0100641)2.64081923
18Ependymoma (HP:0002888)2.57506778
19Abnormality of the labia minora (HP:0012880)2.55425138
20Tubulointerstitial nephritis (HP:0001970)2.52736385
21Degeneration of the lateral corticospinal tracts (HP:0002314)2.44763513
22Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.44763513
23Abnormality of the nasal septum (HP:0000419)2.43286983
24Glioma (HP:0009733)2.41776399
25Hypochromic microcytic anemia (HP:0004840)2.39281640
26Abnormality of chromosome segregation (HP:0002916)2.38439535
27Neoplasm of the oral cavity (HP:0100649)2.37177684
28Deep philtrum (HP:0002002)2.36577079
29Oligodactyly (hands) (HP:0001180)2.34629537
30Truncal obesity (HP:0001956)2.33685389
31Nephroblastoma (Wilms tumor) (HP:0002667)2.29956027
32Impulsivity (HP:0100710)2.29769149
33Duplicated collecting system (HP:0000081)2.29695894
34Abnormality of the left ventricular outflow tract (HP:0011103)2.27416795
35Subaortic stenosis (HP:0001682)2.27416795
36Ectopic kidney (HP:0000086)2.26565601
37Cystic hygroma (HP:0000476)2.25911965
38Abnormality of the renal collecting system (HP:0004742)2.23532980
39Medulloblastoma (HP:0002885)2.22762461
40Abnormality of chromosome stability (HP:0003220)2.22188464
41Transitional cell carcinoma of the bladder (HP:0006740)2.19737141
42Macroorchidism (HP:0000053)2.16573049
43Abnormal auditory evoked potentials (HP:0006958)2.10281128
44Embryonal renal neoplasm (HP:0011794)2.08589223
45Excessive salivation (HP:0003781)2.07760480
46Drooling (HP:0002307)2.07760480
47Abnormality of the hepatic vasculature (HP:0006707)2.07217679
48Clubbing of toes (HP:0100760)2.06868369
49Cafe-au-lait spot (HP:0000957)2.06414482
50Heterotopia (HP:0002282)2.06395324
51Sandal gap (HP:0001852)2.06307573
52Portal hypertension (HP:0001409)2.05680816
53B lymphocytopenia (HP:0010976)2.04998769
54Bladder neoplasm (HP:0009725)2.02967766
55Bladder carcinoma (HP:0002862)2.02967766
56Generalized hypopigmentation of hair (HP:0011358)2.02547086
57Viral hepatitis (HP:0006562)2.01801881
58Aplasia/Hypoplasia involving the sinuses (HP:0009120)2.01355901
59Absent frontal sinuses (HP:0002688)2.01119609
60Abnormality of the corticospinal tract (HP:0002492)2.00462553
61Rhabdomyosarcoma (HP:0002859)2.00459821
62Long clavicles (HP:0000890)2.00070627
63Abnormality of B cell number (HP:0010975)1.98764946
64Recurrent viral infections (HP:0004429)1.95175293
65Anal stenosis (HP:0002025)1.93608123
66Supernumerary spleens (HP:0009799)1.93374546
67Aplasia/Hypoplasia of the tibia (HP:0005772)1.93292237
68Myelodysplasia (HP:0002863)1.93223677
69Supernumerary ribs (HP:0005815)1.90907780
70Tented upper lip vermilion (HP:0010804)1.90704592
71Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.90244815
72Severe combined immunodeficiency (HP:0004430)1.90214788
73Hip dysplasia (HP:0001385)1.89043065
74Facial hemangioma (HP:0000329)1.87976850
75Poor coordination (HP:0002370)1.87896014
76Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.87474598
77Hypoplasia of the maxilla (HP:0000327)1.86340271
78Molar tooth sign on MRI (HP:0002419)1.85727016
79Abnormality of midbrain morphology (HP:0002418)1.85727016
80Autoimmune hemolytic anemia (HP:0001890)1.84980019
81True hermaphroditism (HP:0010459)1.84947794
82Abnormality of the lower motor neuron (HP:0002366)1.84679368
83Widely spaced teeth (HP:0000687)1.84059034
84Absent speech (HP:0001344)1.83520860
85Gait imbalance (HP:0002141)1.82979444
86Curly hair (HP:0002212)1.82612016
87Abnormality of cochlea (HP:0000375)1.82394230
88Abnormality of the renal medulla (HP:0100957)1.80885357
89Narrow palate (HP:0000189)1.80245628
90Abnormality of the frontal sinuses (HP:0002687)1.80188146
91Syringomyelia (HP:0003396)1.80173834
92Spinal cord lesions (HP:0100561)1.80173834
93Esophageal atresia (HP:0002032)1.79021335
94Abnormality of the renal cortex (HP:0011035)1.78758098
95Cortical dysplasia (HP:0002539)1.77939970
96Large earlobe (HP:0009748)1.77625230
97Combined immunodeficiency (HP:0005387)1.77059109
98Hyperventilation (HP:0002883)1.76799382
99Hypoplasia of the thymus (HP:0000778)1.76631457
100Abnormality of the epiphyses of the hand (HP:0005924)1.76394402
101Menstrual irregularities (HP:0000858)1.76348808
102Papilledema (HP:0001085)1.76262378
103Nephrogenic diabetes insipidus (HP:0009806)1.76078804
104Biliary tract neoplasm (HP:0100574)1.75294984
105Short chin (HP:0000331)1.74205471
106Congenital primary aphakia (HP:0007707)1.74011000
107Abnormality of the preputium (HP:0100587)1.73796795
108Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.73524607
109Skull defect (HP:0001362)1.73299964
110Midline defect of the nose (HP:0004122)1.73003624
111Small intestinal stenosis (HP:0012848)1.72788616
112Duodenal stenosis (HP:0100867)1.72788616
113Lip pit (HP:0100267)1.72128487
114Hyperkalemia (HP:0002153)1.72094306
115Gastrointestinal atresia (HP:0002589)1.72092019
116Abnormal hair whorl (HP:0010721)1.71980241
117Nephronophthisis (HP:0000090)1.71663144
118Short foot (HP:0001773)1.71128416
119Long eyelashes (HP:0000527)1.70359355
120Tapered finger (HP:0001182)1.70196650
121Abnormality of the phalanges of the hallux (HP:0010057)1.70030898
122Gaze-evoked nystagmus (HP:0000640)1.70012125
123Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.69986460
124Neoplasm of the small intestine (HP:0100833)1.69123368
125Abnormality of the ileum (HP:0001549)1.69064876
126Abnormal foot bone ossification (HP:0010675)1.68857431
127Gastroesophageal reflux (HP:0002020)1.68659058
128Hypoplastic labia majora (HP:0000059)1.68114900
129Scanning speech (HP:0002168)1.68109347
130Intestinal atresia (HP:0011100)1.68033844
131Occipital encephalocele (HP:0002085)1.68008298
132Gonadotropin excess (HP:0000837)1.67790082
133Aplasia/Hypoplasia of the earlobes (HP:0009906)1.67317034
134Pancreatic fibrosis (HP:0100732)1.67187599
135Febrile seizures (HP:0002373)1.67003601
136Sloping forehead (HP:0000340)1.66052627
137Cupped ear (HP:0000378)1.65988404
138Flat acetabular roof (HP:0003180)1.65592723
139Pancreatic islet-cell hyperplasia (HP:0004510)1.65536281
140Gastrointestinal carcinoma (HP:0002672)1.65467284
141Malignant gastrointestinal tract tumors (HP:0006749)1.65467284
142Cutis marmorata (HP:0000965)1.64897513
143Abnormal lung lobation (HP:0002101)1.64741208
144Arteriovenous malformation (HP:0100026)1.64694898
145Supernumerary bones of the axial skeleton (HP:0009144)1.64677604
146Termporal pattern (HP:0011008)1.64501680
147Insidious onset (HP:0003587)1.64501680
148Aqueductal stenosis (HP:0002410)1.64134368
149Aplasia/Hypoplasia of the uvula (HP:0010293)1.63839922
150Neoplasm of striated muscle (HP:0009728)1.63528875
151Prominent nose (HP:0000448)1.62571796
152Pancreatic cysts (HP:0001737)1.62036315
153Meckel diverticulum (HP:0002245)1.60971179
154Abnormality of incisor morphology (HP:0011063)1.60825739
155Shawl scrotum (HP:0000049)1.60266764
156Neoplasm of the tracheobronchial system (HP:0100552)1.57896811
157Stomach cancer (HP:0012126)1.57736240
158Abnormality of the ischium (HP:0003174)1.56118573
159Abnormality of the incisor (HP:0000676)1.55408931
160Abnormality of secondary sexual hair (HP:0009888)1.54070810
161Abnormality of the axillary hair (HP:0100134)1.54070810
162Enlarged kidneys (HP:0000105)1.53074603
163Genital tract atresia (HP:0001827)1.53048835
164Obsessive-compulsive behavior (HP:0000722)1.51818004
165Blue irides (HP:0000635)1.51357072
166Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.51338324

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ACVR1B3.74383832
2BRD43.61562343
3CDK123.25534138
4AKT32.92385934
5CSNK1A1L2.40395509
6PNCK2.30353231
7EIF2AK32.29386641
8FGFR22.26399304
9FRK2.16228466
10INSRR2.12277927
11YES12.04882595
12MAP3K101.97791034
13SGK21.96465567
14SRPK11.79350182
15CASK1.65464989
16NEK91.65033504
17BRSK21.64959348
18CSNK1G11.59493499
19ZAK1.51220475
20STK391.48530175
21NUAK11.47027999
22SGK4941.43934768
23SGK2231.43934768
24MET1.42582101
25LATS11.41035397
26SGK31.40336494
27CAMKK21.39612211
28CSNK1G31.38968111
29NEK61.37083807
30CAMK1G1.36225580
31SCYL21.36193663
32CSNK1G21.30495293
33TRPM71.27145691
34PKN21.27032363
35PLK31.26295555
36TGFBR11.25754063
37MELK1.20595046
38CAMK1D1.19553092
39MAPK131.19549258
40PLK41.17955789
41CSNK1D1.17680011
42PKN11.17381311
43UHMK11.13782503
44MKNK21.13553476
45JAK11.13210566
46BCR1.10593618
47OXSR11.10203268
48WEE11.09972425
49MAP3K141.09125132
50PLK21.07701657
51BMPR21.06742355
52WNK11.04514155
53GRK11.04276493
54TRIM281.02998876
55SGK10.98605186
56FGFR30.98531661
57KSR10.98088243
58MAP3K60.97964512
59ATM0.96376550
60VRK10.95535617
61MAP3K20.95468240
62CDK90.92571221
63FER0.92548358
64WNK30.92013704
65TNIK0.90250964
66ATR0.89242372
67TEC0.88691995
68STK38L0.87840764
69EEF2K0.86648206
70TLK10.86506973
71CHEK10.83738538
72ITK0.78634773
73MAPK150.78137903
74EPHA40.77392433
75HIPK20.76093048
76PDGFRB0.76086150
77RPS6KA40.74779187
78CDK60.73861298
79IRAK10.73652019
80TTK0.73580485
81STK40.73334599
82CHUK0.72594961
83MAP3K130.72548258
84CDK30.72515862
85RAF10.72044009
86CHEK20.70929935
87CDC70.69938971
88DYRK1A0.69222029
89FLT30.68107556
90NLK0.67977517
91NTRK30.67429130
92SIK30.65342851
93MST40.64192356
94EIF2AK20.64132829
95IRAK20.63863188
96PIK3CG0.63396817
97PRKDC0.62874861
98CDK10.62874257
99NEK20.61996827
100IRAK40.61929296
101HCK0.59976527
102MAP3K70.58438774
103PRKCQ0.58120848
104BTK0.57660528
105STK240.57356183
106EPHA20.55313024
107TYK20.55039092
108MKNK10.54975554
109RPS6KA50.54456677
110TAOK30.54397286
111NEK10.54316562
112CDK40.54107546
113PASK0.53982128
114GSK3B0.53879754
115MAPK140.53387593
116ERBB40.53300743
117EGFR0.51911967
118FES0.51633761
119PDGFRA0.51560326
120EIF2AK10.51217520
121TXK0.50847893
122TGFBR20.50843052
123MAPK100.50416766
124MAP3K40.50089267
125STK100.49930651
126MAP2K70.49870268
127CDK20.49856513
128ERBB30.49805295
129TAF10.48719096
130RPS6KB10.48573418
131SIK10.48458652
132PRKAA20.48395318
133STK30.48195870
134MARK30.47693825
135FGFR10.47433894
136CSK0.46050344
137STK110.45681446
138BMPR1B0.45353773
139SIK20.44652957
140SYK0.43973053
141PLK10.43597995
142CLK10.42960140
143PRKAA10.42179818
144RET0.41999852
145GSK3A0.40997237
146MAPK80.40151497

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009102.48898760
2Fanconi anemia pathway_Homo sapiens_hsa034602.46974380
3Non-homologous end-joining_Homo sapiens_hsa034502.37218756
4Dorso-ventral axis formation_Homo sapiens_hsa043202.29095370
5Systemic lupus erythematosus_Homo sapiens_hsa053222.08036175
6Lysine degradation_Homo sapiens_hsa003102.01360040
7Fatty acid biosynthesis_Homo sapiens_hsa000611.81645486
8Maturity onset diabetes of the young_Homo sapiens_hsa049501.64376830
9Phototransduction_Homo sapiens_hsa047441.62697989
10Phosphatidylinositol signaling system_Homo sapiens_hsa040701.62113968
11Non-small cell lung cancer_Homo sapiens_hsa052231.61125571
12Inositol phosphate metabolism_Homo sapiens_hsa005621.49568314
13mRNA surveillance pathway_Homo sapiens_hsa030151.48080063
14Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.45498474
15Chronic myeloid leukemia_Homo sapiens_hsa052201.43593050
16Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.43162335
17Homologous recombination_Homo sapiens_hsa034401.40784363
18Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.38108797
19Endometrial cancer_Homo sapiens_hsa052131.37421839
20Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.27990409
21Measles_Homo sapiens_hsa051621.25627495
22Alcoholism_Homo sapiens_hsa050341.24576494
23Transcriptional misregulation in cancer_Homo sapiens_hsa052021.22556979
24Thyroid cancer_Homo sapiens_hsa052161.22431067
25ABC transporters_Homo sapiens_hsa020101.22172166
26One carbon pool by folate_Homo sapiens_hsa006701.19896981
27Jak-STAT signaling pathway_Homo sapiens_hsa046301.14282457
28Prostate cancer_Homo sapiens_hsa052151.13454953
29RNA transport_Homo sapiens_hsa030131.12510456
30MicroRNAs in cancer_Homo sapiens_hsa052061.11911145
31NF-kappa B signaling pathway_Homo sapiens_hsa040641.10814436
32Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.10040962
33Glioma_Homo sapiens_hsa052141.09793251
34Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.09566729
35Mismatch repair_Homo sapiens_hsa034301.09397321
36Prolactin signaling pathway_Homo sapiens_hsa049171.09001748
37Renal cell carcinoma_Homo sapiens_hsa052111.08596718
38Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.06685937
39Hepatitis B_Homo sapiens_hsa051611.05572171
40Taste transduction_Homo sapiens_hsa047421.03649818
41Nicotine addiction_Homo sapiens_hsa050331.01587003
42Axon guidance_Homo sapiens_hsa043601.00385144
43Glutamatergic synapse_Homo sapiens_hsa047240.99710529
44Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.99029008
45Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.98746437
46Nucleotide excision repair_Homo sapiens_hsa034200.98528397
47Platelet activation_Homo sapiens_hsa046110.96537516
48Adherens junction_Homo sapiens_hsa045200.96353442
49AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.95352419
50DNA replication_Homo sapiens_hsa030300.95020539
51Ether lipid metabolism_Homo sapiens_hsa005650.94724452
52FoxO signaling pathway_Homo sapiens_hsa040680.92287111
53Vitamin B6 metabolism_Homo sapiens_hsa007500.90789852
54Wnt signaling pathway_Homo sapiens_hsa043100.88650894
55Herpes simplex infection_Homo sapiens_hsa051680.88484752
56Proteoglycans in cancer_Homo sapiens_hsa052050.88072449
57Primary immunodeficiency_Homo sapiens_hsa053400.87945837
58Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.85761963
59Small cell lung cancer_Homo sapiens_hsa052220.85083009
60Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.81817312
61Neurotrophin signaling pathway_Homo sapiens_hsa047220.81642912
62Viral carcinogenesis_Homo sapiens_hsa052030.81286277
63HTLV-I infection_Homo sapiens_hsa051660.81109057
64Focal adhesion_Homo sapiens_hsa045100.80213497
65RNA degradation_Homo sapiens_hsa030180.79938604
66Acute myeloid leukemia_Homo sapiens_hsa052210.79900148
67Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.79811846
68Cell cycle_Homo sapiens_hsa041100.79016993
69ErbB signaling pathway_Homo sapiens_hsa040120.78185618
70Melanoma_Homo sapiens_hsa052180.77113976
71Type II diabetes mellitus_Homo sapiens_hsa049300.77007349
72Thyroid hormone signaling pathway_Homo sapiens_hsa049190.75389397
73Morphine addiction_Homo sapiens_hsa050320.73300612
74RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.73060192
75Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.73023536
76Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.71337464
77TGF-beta signaling pathway_Homo sapiens_hsa043500.71108046
78Basal cell carcinoma_Homo sapiens_hsa052170.70478704
79Colorectal cancer_Homo sapiens_hsa052100.67557911
80Phospholipase D signaling pathway_Homo sapiens_hsa040720.65966471
81Renin secretion_Homo sapiens_hsa049240.65314662
82Sphingolipid signaling pathway_Homo sapiens_hsa040710.65256934
83Toxoplasmosis_Homo sapiens_hsa051450.64472864
84B cell receptor signaling pathway_Homo sapiens_hsa046620.64156860
85Osteoclast differentiation_Homo sapiens_hsa043800.62839318
86Choline metabolism in cancer_Homo sapiens_hsa052310.61845039
87Insulin resistance_Homo sapiens_hsa049310.61630064
88Insulin secretion_Homo sapiens_hsa049110.61522122
89GABAergic synapse_Homo sapiens_hsa047270.61003664
90Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.60952469
91Linoleic acid metabolism_Homo sapiens_hsa005910.60485305
92Autoimmune thyroid disease_Homo sapiens_hsa053200.59838076
93Influenza A_Homo sapiens_hsa051640.59645896
94Hippo signaling pathway_Homo sapiens_hsa043900.58507115
95Long-term potentiation_Homo sapiens_hsa047200.57475122
96Cocaine addiction_Homo sapiens_hsa050300.57280772
97Viral myocarditis_Homo sapiens_hsa054160.57272512
98mTOR signaling pathway_Homo sapiens_hsa041500.57200206
99Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.57190263
100alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.56376678
101Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.56334163
102Oocyte meiosis_Homo sapiens_hsa041140.56328068
103Regulation of actin cytoskeleton_Homo sapiens_hsa048100.55922790
104Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.55217606
105Regulation of autophagy_Homo sapiens_hsa041400.55179535
106Hematopoietic cell lineage_Homo sapiens_hsa046400.54991465
107Pathways in cancer_Homo sapiens_hsa052000.54672616
108Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.54554807
109Sulfur metabolism_Homo sapiens_hsa009200.53210439
110Tight junction_Homo sapiens_hsa045300.53163702
111Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.52556845
112cGMP-PKG signaling pathway_Homo sapiens_hsa040220.52245171
113Leishmaniasis_Homo sapiens_hsa051400.51109152
114Long-term depression_Homo sapiens_hsa047300.50607907
115Pancreatic cancer_Homo sapiens_hsa052120.50371374
116T cell receptor signaling pathway_Homo sapiens_hsa046600.49367535
117Longevity regulating pathway - mammal_Homo sapiens_hsa042110.48952409
118Leukocyte transendothelial migration_Homo sapiens_hsa046700.48560763
119Vitamin digestion and absorption_Homo sapiens_hsa049770.48219777
120Allograft rejection_Homo sapiens_hsa053300.47865370
121Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.47650937
122Chemokine signaling pathway_Homo sapiens_hsa040620.47592069
123Amphetamine addiction_Homo sapiens_hsa050310.47234078
124Hedgehog signaling pathway_Homo sapiens_hsa043400.46373284
125Glucagon signaling pathway_Homo sapiens_hsa049220.45819461
126MAPK signaling pathway_Homo sapiens_hsa040100.45547486
127AMPK signaling pathway_Homo sapiens_hsa041520.44559448
128Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.44256902
129Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.44218432
130Thyroid hormone synthesis_Homo sapiens_hsa049180.44206676
131Circadian rhythm_Homo sapiens_hsa047100.43712160
132Selenocompound metabolism_Homo sapiens_hsa004500.43118124
133NOD-like receptor signaling pathway_Homo sapiens_hsa046210.43044534
134Ras signaling pathway_Homo sapiens_hsa040140.43028099
135p53 signaling pathway_Homo sapiens_hsa041150.42555000
136Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.41923795
137Notch signaling pathway_Homo sapiens_hsa043300.41776521
138Graft-versus-host disease_Homo sapiens_hsa053320.41509439
139cAMP signaling pathway_Homo sapiens_hsa040240.40936493
140Carbohydrate digestion and absorption_Homo sapiens_hsa049730.40113807
141Aldosterone synthesis and secretion_Homo sapiens_hsa049250.39719539
142Rap1 signaling pathway_Homo sapiens_hsa040150.39685489
143Circadian entrainment_Homo sapiens_hsa047130.39655345
144Dopaminergic synapse_Homo sapiens_hsa047280.39250824
145Basal transcription factors_Homo sapiens_hsa030220.38767027
146PI3K-Akt signaling pathway_Homo sapiens_hsa041510.38721968
147Gastric acid secretion_Homo sapiens_hsa049710.38456352

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