FAM206A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proteasome assembly (GO:0043248)5.29650546
2motile cilium assembly (GO:0044458)5.19594125
3piRNA metabolic process (GO:0034587)4.68513517
4regulation of cilium movement (GO:0003352)4.46805030
5axonemal dynein complex assembly (GO:0070286)4.41090076
6establishment of integrated proviral latency (GO:0075713)4.27999634
7positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.25314447
8regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.19799884
9negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.14936192
10DNA unwinding involved in DNA replication (GO:0006268)4.02681197
11terpenoid biosynthetic process (GO:0016114)3.94565022
12anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.93124951
13regulation of cellular amino acid metabolic process (GO:0006521)3.89925030
14mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.83686181
15microtubule depolymerization (GO:0007019)3.75734011
16negative regulation of ligase activity (GO:0051352)3.75576460
17negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.75576460
18purine nucleobase biosynthetic process (GO:0009113)3.63698282
19oxidative phosphorylation (GO:0006119)3.62960493
20ubiquinone biosynthetic process (GO:0006744)3.60494192
21DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.58344501
22positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.58016329
23establishment of viral latency (GO:0019043)3.55818254
24cilium or flagellum-dependent cell motility (GO:0001539)3.53148259
25positive regulation of ligase activity (GO:0051351)3.52082674
26intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.51210376
27signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.51210376
28protein neddylation (GO:0045116)3.51022800
29signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.50639775
30signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.50639775
31signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.50639775
32cullin deneddylation (GO:0010388)3.48245260
33negative regulation of translation, ncRNA-mediated (GO:0040033)3.47717118
34regulation of translation, ncRNA-mediated (GO:0045974)3.47717118
35negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.47717118
36diterpenoid biosynthetic process (GO:0016102)3.44829710
37tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.36725929
38RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.36725929
39DNA damage response, detection of DNA damage (GO:0042769)3.36129475
40ubiquinone metabolic process (GO:0006743)3.34061413
41signal transduction involved in cell cycle checkpoint (GO:0072395)3.34004668
42DNA ligation (GO:0006266)3.33738540
43signal transduction involved in DNA damage checkpoint (GO:0072422)3.32234682
44signal transduction involved in DNA integrity checkpoint (GO:0072401)3.32234682
45protein deneddylation (GO:0000338)3.26524144
46non-recombinational repair (GO:0000726)3.21307000
47double-strand break repair via nonhomologous end joining (GO:0006303)3.21307000
48nucleobase biosynthetic process (GO:0046112)3.19751342
49establishment of protein localization to mitochondrial membrane (GO:0090151)3.18446375
50regulation of mitochondrial translation (GO:0070129)3.17486781
51protein complex biogenesis (GO:0070271)3.16447384
52translesion synthesis (GO:0019985)3.15810612
53mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.15067452
54kynurenine metabolic process (GO:0070189)3.14466612
55regulation of ubiquitin-protein transferase activity (GO:0051438)3.13462437
56pre-miRNA processing (GO:0031054)3.12346189
57meiotic cell cycle (GO:0051321)3.11275707
58regulation of ligase activity (GO:0051340)3.10498015
59mitochondrial respiratory chain complex assembly (GO:0033108)3.05828865
60embryonic camera-type eye development (GO:0031076)3.05565833
61DNA methylation involved in gamete generation (GO:0043046)3.04825951
62energy coupled proton transport, down electrochemical gradient (GO:0015985)3.03382414
63ATP synthesis coupled proton transport (GO:0015986)3.03382414
64tryptophan catabolic process (GO:0006569)3.02260777
65indole-containing compound catabolic process (GO:0042436)3.02260777
66indolalkylamine catabolic process (GO:0046218)3.02260777
67mitochondrial respiratory chain complex I assembly (GO:0032981)3.00750831
68NADH dehydrogenase complex assembly (GO:0010257)3.00750831
69mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.00750831
70regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.99944373
71positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.99944373
72regulation of nuclear cell cycle DNA replication (GO:0033262)2.97384075
73intra-S DNA damage checkpoint (GO:0031573)2.97273571
74aerobic respiration (GO:0009060)2.95745121
75positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.94958825
76regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.94958825
77isoprenoid biosynthetic process (GO:0008299)2.94504267
78ribosome assembly (GO:0042255)2.93541987
79respiratory electron transport chain (GO:0022904)2.92324843
80electron transport chain (GO:0022900)2.91626140
81GMP metabolic process (GO:0046037)2.91131818
82alternative mRNA splicing, via spliceosome (GO:0000380)2.90849731
83male meiosis (GO:0007140)2.90241689
84fusion of sperm to egg plasma membrane (GO:0007342)2.88593181
85rRNA modification (GO:0000154)2.87683495
86transcription elongation from RNA polymerase III promoter (GO:0006385)2.85682397
87termination of RNA polymerase III transcription (GO:0006386)2.85682397
88preassembly of GPI anchor in ER membrane (GO:0016254)2.83628442
89negative regulation of DNA recombination (GO:0045910)2.80470441
90quinone biosynthetic process (GO:1901663)2.80312592
91regulation of cellular amine metabolic process (GO:0033238)2.80201823
92cellular respiration (GO:0045333)2.78608588
93gene silencing by RNA (GO:0031047)2.77752517
94branched-chain amino acid catabolic process (GO:0009083)2.76841576
95DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.75089698
96mitotic sister chromatid segregation (GO:0000070)2.74805423
97negative regulation of protein ubiquitination (GO:0031397)2.72627471
98acrosome reaction (GO:0007340)2.72120672
99mitotic sister chromatid cohesion (GO:0007064)2.71599818
100tryptophan metabolic process (GO:0006568)2.71146674
101regulation of centriole replication (GO:0046599)2.70824797
102respiratory chain complex IV assembly (GO:0008535)2.70462297
103aldehyde catabolic process (GO:0046185)2.69760046
104water-soluble vitamin biosynthetic process (GO:0042364)2.68549723
105meiotic nuclear division (GO:0007126)2.63729416
106multicellular organism reproduction (GO:0032504)2.63431879
107sperm-egg recognition (GO:0035036)2.58698585
108sister chromatid cohesion (GO:0007062)2.57152020
109DNA double-strand break processing (GO:0000729)2.53706283
110epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.52936511
111meiotic chromosome segregation (GO:0045132)2.47630048
112DNA replication checkpoint (GO:0000076)2.46692466
113response to X-ray (GO:0010165)2.45665143
114epithelial cilium movement (GO:0003351)2.44431208
115postreplication repair (GO:0006301)2.42825265
116centriole assembly (GO:0098534)2.36799389
117positive regulation of mRNA catabolic process (GO:0061014)2.36770569
118cellular response to zinc ion (GO:0071294)2.35657995
119chromosome organization involved in meiosis (GO:0070192)2.34846589
120binding of sperm to zona pellucida (GO:0007339)2.34171737
121positive regulation of mRNA 3-end processing (GO:0031442)2.33729274
122negative regulation of DNA-dependent DNA replication (GO:2000104)2.32879682
123regulation of mRNA 3-end processing (GO:0031440)2.31827549
124deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.30589319
125cell-cell recognition (GO:0009988)2.29479377
126tRNA methylation (GO:0030488)2.28691586
127pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.27283570
128male meiosis I (GO:0007141)2.24862356
129kinetochore organization (GO:0051383)2.24575719
130DNA synthesis involved in DNA repair (GO:0000731)2.23795244
131telomere maintenance via semi-conservative replication (GO:0032201)2.21750946
132DNA catabolic process, exonucleolytic (GO:0000738)2.18486583
133termination of RNA polymerase I transcription (GO:0006363)2.18240470
134cell wall macromolecule catabolic process (GO:0016998)2.18095734
135cell wall macromolecule metabolic process (GO:0044036)2.18095734
136DNA strand elongation involved in DNA replication (GO:0006271)2.18087766
137DNA damage response, signal transduction resulting in transcription (GO:0042772)2.17052378
138kinetochore assembly (GO:0051382)2.15884095
139histone H2A acetylation (GO:0043968)2.15557937
140nuclear pore organization (GO:0006999)2.14632620
141cilium movement (GO:0003341)2.14497935
142pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.14383953
143positive regulation of mRNA processing (GO:0050685)2.13701711
144histone mRNA metabolic process (GO:0008334)2.12462609
145DNA alkylation (GO:0006305)2.11867209
146DNA methylation (GO:0006306)2.11867209
147DNA replication-independent nucleosome organization (GO:0034724)2.11437162
148DNA replication-independent nucleosome assembly (GO:0006336)2.11437162
149DNA replication initiation (GO:0006270)2.11403348
150synaptonemal complex assembly (GO:0007130)2.11292388
151DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.11078644
152exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.10388884
153DNA strand elongation (GO:0022616)2.09144858
154regulation of DNA endoreduplication (GO:0032875)2.09070049
155snRNA processing (GO:0016180)2.09029335
156histone exchange (GO:0043486)2.07758308
157regulation of histone H3-K9 methylation (GO:0051570)2.07128864
158DNA integration (GO:0015074)2.06661252
159regulation of non-canonical Wnt signaling pathway (GO:2000050)2.06385867
160regulation of mitotic spindle checkpoint (GO:1903504)2.06063638
161regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.06063638
162regulation of mRNA catabolic process (GO:0061013)2.05799944
163mannosylation (GO:0097502)2.05436847
164CENP-A containing nucleosome assembly (GO:0034080)2.05284788
165spermatid development (GO:0007286)2.05116553
166DNA-dependent DNA replication (GO:0006261)2.04604266
167regulation of B cell receptor signaling pathway (GO:0050855)2.04307342
168centriole replication (GO:0007099)2.04158826
169chromatin remodeling at centromere (GO:0031055)2.03021393
170telomere maintenance via telomere lengthening (GO:0010833)2.00590206
171acrosome assembly (GO:0001675)2.00071965
172plasma membrane fusion (GO:0045026)1.98578560
173DNA methylation or demethylation (GO:0044728)1.98450087
174synaptonemal complex organization (GO:0070193)1.96942515
175telomere maintenance via recombination (GO:0000722)1.96745555
176negative regulation of DNA replication (GO:0008156)1.96634027
177base-excision repair, AP site formation (GO:0006285)1.96546852
178peptidyl-histidine modification (GO:0018202)1.96463316
179regulation of vitamin D biosynthetic process (GO:0060556)1.95520582

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse5.87101698
2E2F7_22180533_ChIP-Seq_HELA_Human5.75067028
3NOTCH1_21737748_ChIP-Seq_TLL_Human3.53875404
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.49509386
5SALL1_21062744_ChIP-ChIP_HESCs_Human3.47080482
6CREB1_15753290_ChIP-ChIP_HEK293T_Human3.21532872
7NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.11143908
8CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.86507402
9RBPJ_22232070_ChIP-Seq_NCS_Mouse2.66816869
10VDR_22108803_ChIP-Seq_LS180_Human2.57146700
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.54292222
12FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.52593526
13TP63_19390658_ChIP-ChIP_HaCaT_Human2.34658119
14MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.31214657
15E2F4_17652178_ChIP-ChIP_JURKAT_Human2.27202687
16E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.25718959
17ZNF274_21170338_ChIP-Seq_K562_Hela2.07655660
18IGF1R_20145208_ChIP-Seq_DFB_Human2.04699236
19HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.93584649
20IRF8_21731497_ChIP-ChIP_J774_Mouse1.88455179
21EGR1_19374776_ChIP-ChIP_THP-1_Human1.88130119
22CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.87419860
23TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.84888266
24JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.78867522
25E2F1_18555785_ChIP-Seq_MESCs_Mouse1.74310013
26IRF8_22096565_ChIP-ChIP_GC-B_Human1.71931898
27KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.69854618
28GABP_17652178_ChIP-ChIP_JURKAT_Human1.68673479
29PADI4_21655091_ChIP-ChIP_MCF-7_Human1.64932212
30MYC_18940864_ChIP-ChIP_HL60_Human1.64811334
31VDR_23849224_ChIP-Seq_CD4+_Human1.61541944
32EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.60411618
33PCGF2_27294783_Chip-Seq_ESCs_Mouse1.58716782
34FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.58022283
35IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.55584020
36MYC_18555785_ChIP-Seq_MESCs_Mouse1.54954778
37SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.53780155
38ELK1_19687146_ChIP-ChIP_HELA_Human1.50281173
39NELFA_20434984_ChIP-Seq_ESCs_Mouse1.50151783
40FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.46258042
41HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.44258660
42HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.44001107
43HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.41867889
44ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.36608953
45YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.35543132
46FLI1_27457419_Chip-Seq_LIVER_Mouse1.34325269
47ELF1_17652178_ChIP-ChIP_JURKAT_Human1.33927195
48SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.33647300
49FOXP3_21729870_ChIP-Seq_TREG_Human1.32208206
50TAF15_26573619_Chip-Seq_HEK293_Human1.32190106
51DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.31404386
52EWS_26573619_Chip-Seq_HEK293_Human1.31083797
53SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.30913665
54EST1_17652178_ChIP-ChIP_JURKAT_Human1.30856113
55AR_21909140_ChIP-Seq_LNCAP_Human1.30422805
56PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.30354153
57FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.30269789
58MYCN_18555785_ChIP-Seq_MESCs_Mouse1.29867996
59KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.29325644
60PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.25880641
61CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.25384014
62NFE2_27457419_Chip-Seq_LIVER_Mouse1.25297777
63FUS_26573619_Chip-Seq_HEK293_Human1.25223966
64ZFP57_27257070_Chip-Seq_ESCs_Mouse1.25168191
65GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.23453414
66ERG_20887958_ChIP-Seq_HPC-7_Mouse1.23264630
67MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.23262850
68PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.22354739
69MYC_18358816_ChIP-ChIP_MESCs_Mouse1.21013493
70HOXB4_20404135_ChIP-ChIP_EML_Mouse1.18584951
71MYC_19079543_ChIP-ChIP_MESCs_Mouse1.18545902
72CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.18476838
73SUZ12_27294783_Chip-Seq_NPCs_Mouse1.17955685
74MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.16338548
75CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.15040403
76E2F1_21310950_ChIP-Seq_MCF-7_Human1.14881990
77THAP11_20581084_ChIP-Seq_MESCs_Mouse1.14526681
78TTF2_22483619_ChIP-Seq_HELA_Human1.14098416
79ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.14074596
80CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.11704821
81HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.11617997
82TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.11023875
83MYC_19030024_ChIP-ChIP_MESCs_Mouse1.08710656
84ELK1_22589737_ChIP-Seq_MCF10A_Human1.07067736
85FOXM1_23109430_ChIP-Seq_U2OS_Human1.06660822
86SCL_19346495_ChIP-Seq_HPC-7_Human1.05996397
87POU3F2_20337985_ChIP-ChIP_501MEL_Human1.04583376
88STAT3_18555785_Chip-Seq_ESCs_Mouse1.01864482
89EZH2_27294783_Chip-Seq_NPCs_Mouse1.01208076
90KDM5A_27292631_Chip-Seq_BREAST_Human1.01110693
91CTBP2_25329375_ChIP-Seq_LNCAP_Human0.98716722
92POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.98601229
93TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.98167664
94YY1_21170310_ChIP-Seq_MESCs_Mouse0.97848680
95STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.97544222
96NANOG_16153702_ChIP-ChIP_HESCs_Human0.96204651
97FOXA1_27270436_Chip-Seq_PROSTATE_Human0.95711862
98FOXA1_25329375_ChIP-Seq_VCAP_Human0.95711862
99MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.95146688
100XRN2_22483619_ChIP-Seq_HELA_Human0.95028129
101GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.94829030
102E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.94263570
103POU5F1_16153702_ChIP-ChIP_HESCs_Human0.94084550
104SRF_21415370_ChIP-Seq_HL-1_Mouse0.93678397
105EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.93669536
106SUZ12_18555785_Chip-Seq_ESCs_Mouse0.93234547
107NMYC_18555785_Chip-Seq_ESCs_Mouse0.92709409
108P53_22387025_ChIP-Seq_ESCs_Mouse0.92550514
109NANOG_18555785_Chip-Seq_ESCs_Mouse0.91913852
110STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.91003979
111GABP_19822575_ChIP-Seq_HepG2_Human0.90631307
112ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.90598012
113MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.90243471
114TP53_22573176_ChIP-Seq_HFKS_Human0.90239777
115EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.90075340
116OCT4_18555785_Chip-Seq_ESCs_Mouse0.89337162
117RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.89300897
118PCGF2_27294783_Chip-Seq_NPCs_Mouse0.89019394
119P300_19829295_ChIP-Seq_ESCs_Human0.89012899
120CTBP1_25329375_ChIP-Seq_LNCAP_Human0.88655534
121P300_18555785_Chip-Seq_ESCs_Mouse0.88084004
122CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.87965745
123MYB_26560356_Chip-Seq_TH2_Human0.87688630
124KLF4_18555785_Chip-Seq_ESCs_Mouse0.86544366
125E2F1_18555785_Chip-Seq_ESCs_Mouse0.86541909
126POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.85920361
127STAT4_19710469_ChIP-ChIP_TH1__Mouse0.85813279
128KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.85661222
129DCP1A_22483619_ChIP-Seq_HELA_Human0.84888633
130RNF2_27304074_Chip-Seq_NSC_Mouse0.84642513
131CRX_20693478_ChIP-Seq_RETINA_Mouse0.84396218
132SPI1_23547873_ChIP-Seq_NB4_Human0.84235395
133SALL4_22934838_ChIP-ChIP_CD34+_Human0.83847580
134IRF1_19129219_ChIP-ChIP_H3396_Human0.83718818
135CIITA_25753668_ChIP-Seq_RAJI_Human0.83485475
136CMYC_18555785_Chip-Seq_ESCs_Mouse0.83424800
137TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.83023808
138SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.83005465
139LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.82062621
140ZFX_18555785_ChIP-Seq_MESCs_Mouse0.81963790
141EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.81304049
142RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.77719110
143IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.77449653
144CBP_20019798_ChIP-Seq_JUKART_Human0.77449653
145KLF5_20875108_ChIP-Seq_MESCs_Mouse0.77232100
146NANOG_19829295_ChIP-Seq_ESCs_Human0.76850096
147SOX2_19829295_ChIP-Seq_ESCs_Human0.76850096

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005409_darkened_coat_color3.08766460
2MP0003186_abnormal_redox_activity2.95745676
3MP0009697_abnormal_copulation2.77879073
4MP0006292_abnormal_olfactory_placode2.69388533
5MP0001986_abnormal_taste_sensitivity2.56342011
6MP0010094_abnormal_chromosome_stability2.54519667
7MP0006035_abnormal_mitochondrial_morpho2.52839473
8MP0005394_taste/olfaction_phenotype2.52181692
9MP0005499_abnormal_olfactory_system2.52181692
10MP0006036_abnormal_mitochondrial_physio2.50709445
11MP0008057_abnormal_DNA_replication2.47401062
12MP0006072_abnormal_retinal_apoptosis2.38029049
13MP0008058_abnormal_DNA_repair2.36285487
14MP0003806_abnormal_nucleotide_metabolis2.31520496
15MP0000372_irregular_coat_pigmentation2.28238575
16MP0008877_abnormal_DNA_methylation2.28209640
17MP0002102_abnormal_ear_morphology2.23552917
18MP0004147_increased_porphyrin_level2.22087769
19MP0003718_maternal_effect2.20268227
20MP0003111_abnormal_nucleus_morphology2.12875415
21MP0005410_abnormal_fertilization2.10654991
22MP0005503_abnormal_tendon_morphology2.04509378
23MP0005174_abnormal_tail_pigmentation1.98615999
24MP0008875_abnormal_xenobiotic_pharmacok1.95410138
25MP0008007_abnormal_cellular_replicative1.91428555
26MP0000015_abnormal_ear_pigmentation1.81853228
27MP0000358_abnormal_cell_content/1.79516516
28MP0005253_abnormal_eye_physiology1.78739742
29MP0004808_abnormal_hematopoietic_stem1.78497159
30MP0004215_abnormal_myocardial_fiber1.78371460
31MP0001188_hyperpigmentation1.74779474
32MP0002396_abnormal_hematopoietic_system1.73288272
33MP0001984_abnormal_olfaction1.65204526
34MP0010030_abnormal_orbit_morphology1.62804885
35MP0002282_abnormal_trachea_morphology1.62624435
36MP0003763_abnormal_thymus_physiology1.61455061
37MP0003077_abnormal_cell_cycle1.57706468
38MP0008995_early_reproductive_senescence1.56806188
39MP0001929_abnormal_gametogenesis1.52819240
40MP0001835_abnormal_antigen_presentation1.49194921
41MP0008260_abnormal_autophagy1.48757292
42MP0002095_abnormal_skin_pigmentation1.46393901
43MP0005551_abnormal_eye_electrophysiolog1.43708811
44MP0002210_abnormal_sex_determination1.43327883
45MP0003011_delayed_dark_adaptation1.43270487
46MP0003693_abnormal_embryo_hatching1.42442266
47MP0000647_abnormal_sebaceous_gland1.41637274
48MP0003941_abnormal_skin_development1.40898924
49MP0003698_abnormal_male_reproductive1.39977882
50MP0004133_heterotaxia1.36783574
51MP0002234_abnormal_pharynx_morphology1.36702906
52MP0001529_abnormal_vocalization1.33782136
53MP0003315_abnormal_perineum_morphology1.33281122
54MP0005671_abnormal_response_to1.32666773
55MP0002736_abnormal_nociception_after1.28931920
56MP0001145_abnormal_male_reproductive1.27558361
57MP0005645_abnormal_hypothalamus_physiol1.26667558
58MP0000703_abnormal_thymus_morphology1.25231744
59MP0005084_abnormal_gallbladder_morpholo1.25087523
60MP0001346_abnormal_lacrimal_gland1.20796690
61MP0002398_abnormal_bone_marrow1.20703026
62MP0002132_abnormal_respiratory_system1.18733756
63MP0004957_abnormal_blastocyst_morpholog1.15956566
64MP0005187_abnormal_penis_morphology1.15922565
65MP0002938_white_spotting1.15395437
66MP0000516_abnormal_urinary_system1.15384168
67MP0005367_renal/urinary_system_phenotyp1.15384168
68MP0000631_abnormal_neuroendocrine_gland1.14157002
69MP0001293_anophthalmia1.13218912
70MP0003786_premature_aging1.12407296
71MP0001790_abnormal_immune_system1.11124615
72MP0005387_immune_system_phenotype1.11124615
73MP0002006_tumorigenesis1.09939526
74MP0001764_abnormal_homeostasis1.09700182
75MP0005171_absent_coat_pigmentation1.09627842
76MP0008932_abnormal_embryonic_tissue1.08268797
77MP0003121_genomic_imprinting1.08010228
78MP0002452_abnormal_antigen_presenting1.06935919
79MP0003252_abnormal_bile_duct1.05612485
80MP0002420_abnormal_adaptive_immunity1.05354192
81MP0003950_abnormal_plasma_membrane1.05130726
82MP0001819_abnormal_immune_cell1.04821842
83MP0000653_abnormal_sex_gland1.03932639
84MP0003787_abnormal_imprinting1.03088836
85MP0001800_abnormal_humoral_immune1.02876300
86MP0009046_muscle_twitch1.02536589
87MP0005636_abnormal_mineral_homeostasis1.02415060
88MP0000716_abnormal_immune_system1.00303027
89MP0009333_abnormal_splenocyte_physiolog0.99861027
90MP0000383_abnormal_hair_follicle0.99735133
91MP0002723_abnormal_immune_serum0.99394033
92MP0002148_abnormal_hypersensitivity_rea0.99316536
93MP0005646_abnormal_pituitary_gland0.98806425
94MP0002177_abnormal_outer_ear0.97453405
95MP0003943_abnormal_hepatobiliary_system0.97193231
96MP0005000_abnormal_immune_tolerance0.96776374
97MP0005397_hematopoietic_system_phenotyp0.95491559
98MP0001545_abnormal_hematopoietic_system0.95491559
99MP0002722_abnormal_immune_system0.94290162
100MP0000678_abnormal_parathyroid_gland0.93612327
101MP0001286_abnormal_eye_development0.92816311
102MP0000749_muscle_degeneration0.92699673
103MP0003136_yellow_coat_color0.92375959
104MP0002751_abnormal_autonomic_nervous0.91641880
105MP0001697_abnormal_embryo_size0.90139692
106MP0003890_abnormal_embryonic-extraembry0.89891333
107MP0002009_preneoplasia0.88689055
108MP0000490_abnormal_crypts_of0.88461416
109MP0002653_abnormal_ependyma_morphology0.88422048
110MP0005391_vision/eye_phenotype0.88190918
111MP0000689_abnormal_spleen_morphology0.86664448
112MP0002429_abnormal_blood_cell0.85979858
113MP0000428_abnormal_craniofacial_morphol0.85970104
114MP0004134_abnormal_chest_morphology0.84644372
115MP0004381_abnormal_hair_follicle0.84549336
116MP0002116_abnormal_craniofacial_bone0.84125982
117MP0008789_abnormal_olfactory_epithelium0.84003899
118MP0009250_abnormal_appendicular_skeleto0.84001921
119MP0001727_abnormal_embryo_implantation0.83632226
120MP0002405_respiratory_system_inflammati0.83351338
121MP0003137_abnormal_impulse_conducting0.83348878
122MP0000350_abnormal_cell_proliferation0.82883550
123MP0005670_abnormal_white_adipose0.82742920
124MP0001119_abnormal_female_reproductive0.82329176
125MP0002163_abnormal_gland_morphology0.82076521
126MP0002075_abnormal_coat/hair_pigmentati0.81821779
127MP0000681_abnormal_thyroid_gland0.81503116
128MP0005075_abnormal_melanosome_morpholog0.80363953
129MP0003385_abnormal_body_wall0.80357716
130MP0002166_altered_tumor_susceptibility0.77834953
131MP0005647_abnormal_sex_gland0.77315309
132MP0002084_abnormal_developmental_patter0.75954191
133MP0000566_synostosis0.75188416
134MP0002160_abnormal_reproductive_system0.74140873
135MP0009785_altered_susceptibility_to0.73712942
136MP0000049_abnormal_middle_ear0.73607914
137MP0000313_abnormal_cell_death0.73563353
138MP0002085_abnormal_embryonic_tissue0.73294793
139MP0002419_abnormal_innate_immunity0.72744970
140MP0002233_abnormal_nose_morphology0.72610179
141MP0001186_pigmentation_phenotype0.71772727
142MP0003936_abnormal_reproductive_system0.71495246
143MP0006054_spinal_hemorrhage0.70809065
144MP0002933_joint_inflammation0.70558758
145MP0000685_abnormal_immune_system0.70518085
146MP0002090_abnormal_vision0.69436400
147MP0005332_abnormal_amino_acid0.69054294
148MP0003937_abnormal_limbs/digits/tail_de0.68822121
149MP0002161_abnormal_fertility/fecundity0.68663443
150MP0001905_abnormal_dopamine_level0.68601699
151MP0002638_abnormal_pupillary_reflex0.67926255
152MP0010307_abnormal_tumor_latency0.67642744
153MP0005025_abnormal_response_to0.66758998
154MP0003938_abnormal_ear_development0.66009126
155MP0000465_gastrointestinal_hemorrhage0.65947925
156MP0002109_abnormal_limb_morphology0.65848388
157MP0002080_prenatal_lethality0.65783274
158MP0005195_abnormal_posterior_eye0.65453533
159MP0003045_fibrosis0.64939724
160MP0003221_abnormal_cardiomyocyte_apopto0.62399598
161MP0009384_cardiac_valve_regurgitation0.61888778
162MP0000427_abnormal_hair_cycle0.61648872

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.60895859
2Dynein arm defect of respiratory motile cilia (HP:0012255)4.09564236
3Absent/shortened dynein arms (HP:0200106)4.09564236
4Overriding aorta (HP:0002623)4.05365732
5Hyperacusis (HP:0010780)3.81931876
6Acute necrotizing encephalopathy (HP:0006965)3.78780743
7Mitochondrial inheritance (HP:0001427)3.66932425
8Elfin facies (HP:0004428)3.60647871
9Abnormal respiratory motile cilium morphology (HP:0005938)3.57362162
10Abnormal respiratory epithelium morphology (HP:0012253)3.57362162
11Abnormal respiratory motile cilium physiology (HP:0012261)3.56271812
12Abnormal mitochondria in muscle tissue (HP:0008316)3.54418602
13Renovascular hypertension (HP:0100817)3.48298735
14Flat cornea (HP:0007720)3.47479356
15Renal duplication (HP:0000075)3.40782904
16Acute encephalopathy (HP:0006846)3.39912478
17Chromosomal breakage induced by crosslinking agents (HP:0003221)3.36297737
18Chromsome breakage (HP:0040012)3.27695742
19Rhinitis (HP:0012384)3.23131574
20Progressive macrocephaly (HP:0004481)3.18841147
21Increased CSF lactate (HP:0002490)3.18368042
22Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)3.06411526
23Hepatocellular necrosis (HP:0001404)3.04898857
24Abnormality of midbrain morphology (HP:0002418)3.03181172
25Molar tooth sign on MRI (HP:0002419)3.03181172
26Abnormal ciliary motility (HP:0012262)2.96932876
27Pancreatic fibrosis (HP:0100732)2.95360432
28Abnormality of cochlea (HP:0000375)2.93158603
29Hepatic necrosis (HP:0002605)2.91990585
30Increased nuchal translucency (HP:0010880)2.87815885
31Chronic otitis media (HP:0000389)2.84596336
32Medial flaring of the eyebrow (HP:0010747)2.82381309
33Abnormality of the carotid arteries (HP:0005344)2.70754382
34Insomnia (HP:0100785)2.68912298
35Congenital primary aphakia (HP:0007707)2.64900814
36Cerebral edema (HP:0002181)2.63078683
37Increased hepatocellular lipid droplets (HP:0006565)2.62601978
38Severe visual impairment (HP:0001141)2.59148597
39Decreased activity of mitochondrial respiratory chain (HP:0008972)2.58873171
40Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.58873171
41Gait imbalance (HP:0002141)2.50783400
42Sensory axonal neuropathy (HP:0003390)2.50770074
433-Methylglutaconic aciduria (HP:0003535)2.46368127
44Abnormality of lateral ventricle (HP:0030047)2.40330764
45Toxemia of pregnancy (HP:0100603)2.39115316
46Chronic bronchitis (HP:0004469)2.38421764
47Chronic sinusitis (HP:0011109)2.38014536
48Nephrogenic diabetes insipidus (HP:0009806)2.34274860
49Increased serum lactate (HP:0002151)2.34093979
50Lipid accumulation in hepatocytes (HP:0006561)2.32883271
51Aplasia/Hypoplasia of the tongue (HP:0010295)2.30869655
52Lactic acidosis (HP:0003128)2.28562292
53Reduced antithrombin III activity (HP:0001976)2.27194965
54Aplasia/Hypoplasia of the fovea (HP:0008060)2.26535201
55Hypoplasia of the fovea (HP:0007750)2.26535201
56Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.20957563
57Abnormality of alanine metabolism (HP:0010916)2.20957563
58Hyperalaninemia (HP:0003348)2.20957563
59Duplicated collecting system (HP:0000081)2.20065604
60Facial cleft (HP:0002006)2.19396785
61Abnormality of the diencephalon (HP:0010662)2.19392134
62Morphological abnormality of the inner ear (HP:0011390)2.19240103
63Renal Fanconi syndrome (HP:0001994)2.18125350
64Abnormality of the labia minora (HP:0012880)2.16121891
65Ectopic kidney (HP:0000086)2.16077353
66Hyperglycinemia (HP:0002154)2.12906494
67Oculomotor apraxia (HP:0000657)2.12500290
68Dyskinesia (HP:0100660)2.09663562
69Hyperglycinuria (HP:0003108)2.08348846
70Carpal bone hypoplasia (HP:0001498)2.06379333
71Abnormality of serine family amino acid metabolism (HP:0010894)2.05572627
72Abnormality of glycine metabolism (HP:0010895)2.05572627
73Patchy hypopigmentation of hair (HP:0011365)2.05568038
74Abnormality of the preputium (HP:0100587)2.05310602
75Abnormality of the renal collecting system (HP:0004742)2.05022888
76Bowel diverticulosis (HP:0005222)2.03361710
77Bronchiectasis (HP:0002110)2.01497201
78Increased serum pyruvate (HP:0003542)2.00906000
79Overlapping toe (HP:0001845)1.99643022
80Abnormality of the fovea (HP:0000493)1.98984097
81Aplasia/Hypoplasia of the uvula (HP:0010293)1.98966575
82Meckel diverticulum (HP:0002245)1.98610063
83Methylmalonic acidemia (HP:0002912)1.97365501
84Abnormality of the renal medulla (HP:0100957)1.95621799
85Absent eyebrow (HP:0002223)1.95049461
86Sclerocornea (HP:0000647)1.94974837
87Reticulocytopenia (HP:0001896)1.94582925
88Bladder diverticulum (HP:0000015)1.90752837
89Abnormality of macular pigmentation (HP:0008002)1.88794946
90Genital tract atresia (HP:0001827)1.88771763
91Nasal polyposis (HP:0100582)1.88686176
92Vaginal atresia (HP:0000148)1.88169016
93Generalized aminoaciduria (HP:0002909)1.88095754
94Occipital encephalocele (HP:0002085)1.87411965
95Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.86702513
96Abnormal protein N-linked glycosylation (HP:0012347)1.86702513
97Abnormal protein glycosylation (HP:0012346)1.86702513
98Abnormal glycosylation (HP:0012345)1.86702513
99Increased intramyocellular lipid droplets (HP:0012240)1.86066754
100Exercise intolerance (HP:0003546)1.85677144
101Bronchitis (HP:0012387)1.84361100
102Megalocornea (HP:0000485)1.82832341
103Lethargy (HP:0001254)1.81939330
104Abnormality of the ileum (HP:0001549)1.81425965
105Degeneration of anterior horn cells (HP:0002398)1.81306295
106Abnormality of the anterior horn cell (HP:0006802)1.81306295
107Pendular nystagmus (HP:0012043)1.80576566
108Duplication of thumb phalanx (HP:0009942)1.79823559
109Obsessive-compulsive behavior (HP:0000722)1.78914934
110Aganglionic megacolon (HP:0002251)1.78502119
111Bile duct proliferation (HP:0001408)1.77824994
112Abnormal biliary tract physiology (HP:0012439)1.77824994
113Abnormality of DNA repair (HP:0003254)1.75953838
114Abnormality of serum amino acid levels (HP:0003112)1.75911915
115Abnormality of chromosome stability (HP:0003220)1.75910904
116Abnormality of the fingertips (HP:0001211)1.75052918
117Pancreatic cysts (HP:0001737)1.74880714
118Deep philtrum (HP:0002002)1.73504000
119Anencephaly (HP:0002323)1.73092654
120Nephronophthisis (HP:0000090)1.72888716
121Short tibia (HP:0005736)1.72191135
122Absent rod-and cone-mediated responses on ERG (HP:0007688)1.71110065
123Abnormal delayed hypersensitivity skin test (HP:0002963)1.71073880
124Respiratory failure (HP:0002878)1.71015384
125Absent septum pellucidum (HP:0001331)1.70971457
126Postnatal microcephaly (HP:0005484)1.70741007
127Patellar dislocation (HP:0002999)1.70411857
128Sloping forehead (HP:0000340)1.69851846
129Abolished electroretinogram (ERG) (HP:0000550)1.69386786
130Aplastic anemia (HP:0001915)1.68782659
131Congenital hepatic fibrosis (HP:0002612)1.68141131
132Abnormality of the phalanges of the hallux (HP:0010057)1.65323771
133Recurrent sinusitis (HP:0011108)1.63875887
134Abnormal hair whorl (HP:0010721)1.62892349
135White forelock (HP:0002211)1.62141438
136Type I transferrin isoform profile (HP:0003642)1.61352740
137Albinism (HP:0001022)1.61317559
138Congenital stationary night blindness (HP:0007642)1.61135815
139Polygenic inheritance (HP:0010982)1.60243744
140Clubbing of toes (HP:0100760)1.60162085
141Small intestinal stenosis (HP:0012848)1.59882564
142Duodenal stenosis (HP:0100867)1.59882564
143Myelodysplasia (HP:0002863)1.57205846
144Hypoplasia of the capital femoral epiphysis (HP:0003090)1.56463418
145Birth length less than 3rd percentile (HP:0003561)1.55918419
146Recurrent otitis media (HP:0000403)1.55825853
147Central scotoma (HP:0000603)1.54653454
148Aortic valve stenosis (HP:0001650)1.54634602
149Premature graying of hair (HP:0002216)1.51780310
150Median cleft lip (HP:0000161)1.50567340
151Abnormal rod and cone electroretinograms (HP:0008323)1.50441847
152Abnormal lung lobation (HP:0002101)1.49237539
153Recurrent bronchitis (HP:0002837)1.48320657
154Volvulus (HP:0002580)1.48014550
155Periorbital edema (HP:0100539)1.47635166
156True hermaphroditism (HP:0010459)1.47426571
157Short thumb (HP:0009778)1.46984211
158Postaxial foot polydactyly (HP:0001830)1.46799941
159Preaxial hand polydactyly (HP:0001177)1.46091453
160Recurrent pneumonia (HP:0006532)1.45981017
161IgM deficiency (HP:0002850)1.45381427
162IgG deficiency (HP:0004315)1.45362931
163Tubulointerstitial nephritis (HP:0001970)1.43982252
164Tracheoesophageal fistula (HP:0002575)1.43622028
165Obstructive lung disease (HP:0006536)1.43577331
166Chronic obstructive pulmonary disease (HP:0006510)1.43577331
167Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.43542833

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK163.72573716
2STK38L3.38566909
3CCNB13.04918211
4BMPR1B2.89555965
5TXK2.63427432
6TRIM282.59683826
7YES12.57960613
8PASK2.41406818
9VRK22.34549077
10ZAK2.34113838
11CDC72.29898217
12VRK12.25699523
13TNIK2.25698469
14MAP4K12.19101685
15BCR2.16669354
16SRPK12.15870765
17IRAK42.13435340
18NEK12.08509744
19MAP3K122.08185612
20MAP4K22.04526915
21MST42.02498251
22GRK11.99375130
23OXSR11.90822981
24BRD41.86597972
25PBK1.84864027
26MKNK21.81570773
27PLK41.80887866
28BLK1.78789626
29PRKD31.77368330
30MKNK11.75861296
31ATR1.74393070
32RPS6KA41.65111305
33TEC1.60353059
34TESK11.53492822
35WNK31.51525400
36CDK81.47056244
37NEK61.46090627
38BUB11.45821502
39CLK11.44290180
40NLK1.42039266
41CDK31.39782702
42BTK1.36623144
43CSNK1G31.35943507
44BCKDK1.35590762
45NME11.30961431
46ZAP701.22579084
47IRAK31.19862728
48CDK121.19612026
49CSNK1G11.18714993
50DYRK31.18130477
51BRSK11.13425925
52CSNK1G21.13389427
53CSNK1A1L1.13185800
54IRAK11.10930325
55CDK71.10450084
56JAK31.09476148
57FRK1.06838908
58PLK21.06609528
59TIE11.05197818
60NEK21.05041699
61CHEK21.03488164
62NME21.03275359
63HCK1.01093069
64AKT31.00886164
65MAP3K140.98766110
66SCYL20.98473093
67ERBB30.97075917
68DYRK20.95115190
69TLK10.94476880
70STK390.93873442
71EIF2AK20.90503076
72PINK10.89233340
73TYK20.86641446
74ATM0.84584399
75CHEK10.84518051
76PLK10.84219419
77SYK0.84127894
78ACVR1B0.82932140
79BRSK20.82729444
80TNK20.80595012
81TTK0.79313580
82CDK40.77882260
83PNCK0.77525125
84LYN0.77013642
85PLK30.75363801
86IKBKB0.75226654
87PDK20.74069420
88EIF2AK30.73188601
89FLT30.72691370
90ITK0.72473839
91MAPK130.71670625
92EPHA20.71669952
93AURKB0.71374325
94TGFBR10.70426290
95CDK190.68427689
96LCK0.68212074
97STK30.67128066
98MAP2K70.64981228
99TSSK60.64745959
100TRPM70.64571415
101PRKD20.64525975
102LIMK10.64244963
103INSRR0.63841065
104EPHA40.63405748
105MAPK70.59265212
106PDGFRB0.58378685
107DYRK1A0.58302582
108PIM20.57296430
109CASK0.56336292
110STK380.55304344
111MAP3K40.54789663
112MINK10.54647620
113MAPKAPK50.53826296
114KIT0.53439070
115TAF10.52467882
116DAPK10.51919032
117RPS6KA50.51304053
118MAPK150.50835303
119CDK10.50762590
120DMPK0.48527244
121WNK40.46651423
122MST1R0.46148097
123CDK20.45031365
124BMPR20.42527789
125WNK10.42266184
126FES0.41805562
127TAOK10.40785928
128SIK30.40546155
129TESK20.40376578
130PAK40.39046530
131BRAF0.38737880
132ABL10.37431256
133PDK40.37181714
134PDK30.37181714
135PRKCE0.36598321
136CSNK2A10.35974132
137CSNK2A20.35853855
138IKBKE0.34698500
139CSNK1A10.34441030
140ADRBK20.32597678
141CDK140.32322759
142MYLK0.31522258
143CDK180.31447314
144CHUK0.31358725
145EIF2AK10.31180734
146FGFR30.31092513
147WEE10.30321576
148NUAK10.29995157
149ERBB40.28418110
150AURKA0.27732933
151FER0.27171848

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001902.72173876
2Homologous recombination_Homo sapiens_hsa034402.49334743
3Parkinsons disease_Homo sapiens_hsa050122.45025974
4DNA replication_Homo sapiens_hsa030302.44788487
5Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.27495650
6Fanconi anemia pathway_Homo sapiens_hsa034602.12734643
7Huntingtons disease_Homo sapiens_hsa050162.03461754
8Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.03176271
9Base excision repair_Homo sapiens_hsa034101.96544534
10Basal transcription factors_Homo sapiens_hsa030221.90040757
11Sulfur relay system_Homo sapiens_hsa041221.89012334
122-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.77999086
13Propanoate metabolism_Homo sapiens_hsa006401.74853754
14Spliceosome_Homo sapiens_hsa030401.72680317
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.70842186
16Mismatch repair_Homo sapiens_hsa034301.68687271
17Cell cycle_Homo sapiens_hsa041101.65894444
18Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.62845610
19Primary immunodeficiency_Homo sapiens_hsa053401.61726894
20RNA polymerase_Homo sapiens_hsa030201.61304200
21Nucleotide excision repair_Homo sapiens_hsa034201.59073465
22Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.57527360
23Cysteine and methionine metabolism_Homo sapiens_hsa002701.54797138
24RNA transport_Homo sapiens_hsa030131.51261905
25Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.49019455
26RNA degradation_Homo sapiens_hsa030181.46954449
27Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.44819874
28Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.42621963
29Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.39106116
30Fatty acid elongation_Homo sapiens_hsa000621.34512271
31Non-homologous end-joining_Homo sapiens_hsa034501.34250632
32Primary bile acid biosynthesis_Homo sapiens_hsa001201.34165758
33Protein export_Homo sapiens_hsa030601.33920560
34Alzheimers disease_Homo sapiens_hsa050101.33438309
35Folate biosynthesis_Homo sapiens_hsa007901.29041728
36Glutathione metabolism_Homo sapiens_hsa004801.27281284
37Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.25958653
38Steroid biosynthesis_Homo sapiens_hsa001001.25842511
39Ribosome_Homo sapiens_hsa030101.24590772
40Herpes simplex infection_Homo sapiens_hsa051681.23040313
41Pyrimidine metabolism_Homo sapiens_hsa002401.22104185
42Graft-versus-host disease_Homo sapiens_hsa053321.20131127
43Pyruvate metabolism_Homo sapiens_hsa006201.18751563
44Glycosaminoglycan degradation_Homo sapiens_hsa005311.16018183
45NF-kappa B signaling pathway_Homo sapiens_hsa040641.15499882
46Antigen processing and presentation_Homo sapiens_hsa046121.14111169
47Regulation of autophagy_Homo sapiens_hsa041401.11626823
48Measles_Homo sapiens_hsa051621.09774152
49Sulfur metabolism_Homo sapiens_hsa009201.08990438
50Allograft rejection_Homo sapiens_hsa053301.08762168
51mRNA surveillance pathway_Homo sapiens_hsa030151.08137736
52Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.08038383
53Butanoate metabolism_Homo sapiens_hsa006501.06373001
54One carbon pool by folate_Homo sapiens_hsa006701.05430791
55Hematopoietic cell lineage_Homo sapiens_hsa046401.05198650
56Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.05001019
57Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.04743776
58Autoimmune thyroid disease_Homo sapiens_hsa053201.01878066
59Proteasome_Homo sapiens_hsa030501.00989858
60Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.98850594
61Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.98753937
62N-Glycan biosynthesis_Homo sapiens_hsa005100.97956649
63Tryptophan metabolism_Homo sapiens_hsa003800.97255611
64Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.94937399
65Leishmaniasis_Homo sapiens_hsa051400.94434893
66T cell receptor signaling pathway_Homo sapiens_hsa046600.94384943
67Legionellosis_Homo sapiens_hsa051340.94175841
68Sphingolipid metabolism_Homo sapiens_hsa006000.92937894
69Intestinal immune network for IgA production_Homo sapiens_hsa046720.92306000
70p53 signaling pathway_Homo sapiens_hsa041150.92247249
71Viral myocarditis_Homo sapiens_hsa054160.92171011
72Type I diabetes mellitus_Homo sapiens_hsa049400.91519563
73Transcriptional misregulation in cancer_Homo sapiens_hsa052020.89478343
74Peroxisome_Homo sapiens_hsa041460.89360751
75Toll-like receptor signaling pathway_Homo sapiens_hsa046200.89201375
76Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.89184271
77HTLV-I infection_Homo sapiens_hsa051660.89115532
78Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.88442783
79Chemical carcinogenesis_Homo sapiens_hsa052040.87957766
80Pentose and glucuronate interconversions_Homo sapiens_hsa000400.87244653
81SNARE interactions in vesicular transport_Homo sapiens_hsa041300.86529371
82Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.86116282
83Drug metabolism - other enzymes_Homo sapiens_hsa009830.85817166
84Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.85407055
85Metabolic pathways_Homo sapiens_hsa011000.84591725
86Caffeine metabolism_Homo sapiens_hsa002320.84149151
87Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.83692692
88Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.83321114
89Purine metabolism_Homo sapiens_hsa002300.82556010
90Retinol metabolism_Homo sapiens_hsa008300.82196296
91Steroid hormone biosynthesis_Homo sapiens_hsa001400.78790874
92Asthma_Homo sapiens_hsa053100.77228370
93Collecting duct acid secretion_Homo sapiens_hsa049660.74872310
94NOD-like receptor signaling pathway_Homo sapiens_hsa046210.73939549
95Epstein-Barr virus infection_Homo sapiens_hsa051690.72592779
96B cell receptor signaling pathway_Homo sapiens_hsa046620.72083877
97Biosynthesis of amino acids_Homo sapiens_hsa012300.71910598
98Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.71256040
99Jak-STAT signaling pathway_Homo sapiens_hsa046300.70931552
100beta-Alanine metabolism_Homo sapiens_hsa004100.70061036
101Wnt signaling pathway_Homo sapiens_hsa043100.69874202
102Hepatitis B_Homo sapiens_hsa051610.68646054
103Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.68569122
104RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.67572723
105Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.66949665
106Shigellosis_Homo sapiens_hsa051310.66625068
107Carbon metabolism_Homo sapiens_hsa012000.66149474
108Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.66010247
109Other glycan degradation_Homo sapiens_hsa005110.65594050
110Chronic myeloid leukemia_Homo sapiens_hsa052200.65491560
111Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.64448664
112Malaria_Homo sapiens_hsa051440.63019239
113Osteoclast differentiation_Homo sapiens_hsa043800.62860836
114Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.61471972
115Basal cell carcinoma_Homo sapiens_hsa052170.61284874
116Nitrogen metabolism_Homo sapiens_hsa009100.60462939
117Pentose phosphate pathway_Homo sapiens_hsa000300.60373907
118Viral carcinogenesis_Homo sapiens_hsa052030.59523592
119TNF signaling pathway_Homo sapiens_hsa046680.59463122
120Influenza A_Homo sapiens_hsa051640.58071091
121Ether lipid metabolism_Homo sapiens_hsa005650.54803550
122Circadian rhythm_Homo sapiens_hsa047100.54236023
123TGF-beta signaling pathway_Homo sapiens_hsa043500.53405578
124Linoleic acid metabolism_Homo sapiens_hsa005910.52849591
125Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.52176946
126Chemokine signaling pathway_Homo sapiens_hsa040620.51800126
127MicroRNAs in cancer_Homo sapiens_hsa052060.49642629
128Tuberculosis_Homo sapiens_hsa051520.49453613
129Tyrosine metabolism_Homo sapiens_hsa003500.48756494
130Arginine and proline metabolism_Homo sapiens_hsa003300.46546283
131Cardiac muscle contraction_Homo sapiens_hsa042600.46143555
132Oocyte meiosis_Homo sapiens_hsa041140.45777290
133Pathways in cancer_Homo sapiens_hsa052000.45768548
134Acute myeloid leukemia_Homo sapiens_hsa052210.44997992
135Phototransduction_Homo sapiens_hsa047440.43988700
136Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.43956991
137Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.43860746
138Selenocompound metabolism_Homo sapiens_hsa004500.43568102
139Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.43329967
140MAPK signaling pathway_Homo sapiens_hsa040100.43286116
141Rheumatoid arthritis_Homo sapiens_hsa053230.42752841
142Salmonella infection_Homo sapiens_hsa051320.42681295
143Colorectal cancer_Homo sapiens_hsa052100.41397693
144Dorso-ventral axis formation_Homo sapiens_hsa043200.40998989
145Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.40974077
146Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.40104833
147Toxoplasmosis_Homo sapiens_hsa051450.40071597
148Hedgehog signaling pathway_Homo sapiens_hsa043400.39552570
149Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.39452843
150Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.39028543
151Fatty acid metabolism_Homo sapiens_hsa012120.38818471
152ErbB signaling pathway_Homo sapiens_hsa040120.38448822
153Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.38142004
154Olfactory transduction_Homo sapiens_hsa047400.38110121
155Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.37868138
156Fatty acid degradation_Homo sapiens_hsa000710.37458307
157Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.35596218
158Arachidonic acid metabolism_Homo sapiens_hsa005900.28348225
159Starch and sucrose metabolism_Homo sapiens_hsa005000.26500947
160Vibrio cholerae infection_Homo sapiens_hsa051100.22431059
161Fatty acid biosynthesis_Homo sapiens_hsa000610.20101776

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