FAM196A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of vascular permeability (GO:0043117)5.86743044
2presynaptic membrane assembly (GO:0097105)5.84614592
3neuron cell-cell adhesion (GO:0007158)5.45005340
4presynaptic membrane organization (GO:0097090)5.35514481
5neurotransmitter-gated ion channel clustering (GO:0072578)5.18513513
6vocalization behavior (GO:0071625)5.07616742
7G-protein coupled glutamate receptor signaling pathway (GO:0007216)5.01122474
8synaptic vesicle exocytosis (GO:0016079)4.93675242
9regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.93557739
10negative regulation of synaptic transmission, GABAergic (GO:0032229)4.87278387
11tachykinin receptor signaling pathway (GO:0007217)4.87251302
12positive regulation of action potential (GO:0045760)4.63746357
13regulation of penile erection (GO:0060405)4.56323974
14startle response (GO:0001964)4.50290928
15postsynaptic membrane organization (GO:0001941)4.47361187
16protein localization to synapse (GO:0035418)4.47309799
17regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.41635624
18gamma-aminobutyric acid signaling pathway (GO:0007214)4.39903998
19positive regulation of synapse maturation (GO:0090129)4.32468957
20retinal rod cell development (GO:0046548)4.30137599
21behavioral response to nicotine (GO:0035095)4.23818979
22positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.20529832
23response to auditory stimulus (GO:0010996)4.19369265
24regulation of short-term neuronal synaptic plasticity (GO:0048172)4.18719059
25regulation of synaptic vesicle exocytosis (GO:2000300)4.13901623
26regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.10982843
27synaptic vesicle endocytosis (GO:0048488)4.05734505
28nonmotile primary cilium assembly (GO:0035058)4.02353554
29regulation of synapse maturation (GO:0090128)3.99583483
30neuronal action potential propagation (GO:0019227)3.97677673
31synaptic vesicle docking involved in exocytosis (GO:0016081)3.94885030
32regulation of glutamate receptor signaling pathway (GO:1900449)3.91161943
33regulation of synaptic transmission, glutamatergic (GO:0051966)3.90714654
34glutamate receptor signaling pathway (GO:0007215)3.90283679
35neuron-neuron synaptic transmission (GO:0007270)3.86534536
36alanine transport (GO:0032328)3.84726737
37long-term synaptic potentiation (GO:0060291)3.83747597
38cerebellar granule cell differentiation (GO:0021707)3.82979091
39positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.82647426
40positive regulation of synapse assembly (GO:0051965)3.82234999
41innervation (GO:0060384)3.79480343
42proline transport (GO:0015824)3.76707284
43negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.76485154
44synaptic transmission, glutamatergic (GO:0035249)3.74814508
45glutamate secretion (GO:0014047)3.68398717
46locomotory exploration behavior (GO:0035641)3.68283593
47striatum development (GO:0021756)3.65385509
48regulation of synaptic vesicle transport (GO:1902803)3.57667163
49membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.57419717
50pyrimidine nucleobase catabolic process (GO:0006208)3.53956528
51synapse assembly (GO:0007416)3.52902284
52positive regulation of synaptic transmission, GABAergic (GO:0032230)3.48193307
53neurotransmitter secretion (GO:0007269)3.48162335
54response to histamine (GO:0034776)3.40292011
55aggressive behavior (GO:0002118)3.39565132
56ionotropic glutamate receptor signaling pathway (GO:0035235)3.39423599
57detection of light stimulus involved in sensory perception (GO:0050962)3.38692295
58detection of light stimulus involved in visual perception (GO:0050908)3.38692295
59dendritic spine morphogenesis (GO:0060997)3.37180745
60regulation of action potential (GO:0098900)3.28794576
61positive regulation of uterine smooth muscle contraction (GO:0070474)3.28187808
62atrial cardiac muscle cell action potential (GO:0086014)3.28168356
63axonal fasciculation (GO:0007413)3.27664254
64cellular potassium ion homeostasis (GO:0030007)3.22473780
65neuron recognition (GO:0008038)3.17341661
66negative regulation of cytosolic calcium ion concentration (GO:0051481)3.15583958
67positive regulation of dendritic spine morphogenesis (GO:0061003)3.14764007
68regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.12006589
69neurotransmitter transport (GO:0006836)3.10413856
70regulation of synaptic transmission, GABAergic (GO:0032228)3.09934640
71auditory behavior (GO:0031223)3.06130168
72urinary tract smooth muscle contraction (GO:0014848)3.04720749
73regulation of synapse assembly (GO:0051963)3.04678164
74gamma-aminobutyric acid transport (GO:0015812)3.03752082
75righting reflex (GO:0060013)3.03306841
76retinal cone cell development (GO:0046549)3.01383371
77dendrite development (GO:0016358)2.99879354
78regulation of neurotransmitter secretion (GO:0046928)2.99301360
79membrane hyperpolarization (GO:0060081)2.99284698
80regulation of fever generation (GO:0031620)2.99212835
81regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.97537612
82regulation of axon extension involved in axon guidance (GO:0048841)2.97379751
83calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.96087773
84protein localization to cilium (GO:0061512)2.95003133
85dendrite morphogenesis (GO:0048813)2.94727906
86exploration behavior (GO:0035640)2.94050158
87synaptic vesicle transport (GO:0048489)2.92148097
88establishment of synaptic vesicle localization (GO:0097480)2.92148097
89transferrin transport (GO:0033572)2.91637304
90L-serine transport (GO:0015825)2.90537027
91negative regulation of dendrite morphogenesis (GO:0050774)2.89830390
92mechanosensory behavior (GO:0007638)2.89112432
93negative regulation of dendrite development (GO:2000171)2.87217427
94eye photoreceptor cell development (GO:0042462)2.86059428
95nucleobase catabolic process (GO:0046113)2.85944642
96learning (GO:0007612)2.85890697
97synaptic vesicle maturation (GO:0016188)2.84250121
98regulation of neurotransmitter transport (GO:0051588)2.83834374
99regulation of respiratory system process (GO:0044065)2.83749242
100positive regulation of synaptic transmission (GO:0050806)2.82451973
101positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.81486769
102regulation of postsynaptic membrane potential (GO:0060078)2.81257848
103positive regulation of membrane potential (GO:0045838)2.80309134
104regulation of excitatory postsynaptic membrane potential (GO:0060079)2.80023507
105homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.79889909
106regulation of axon guidance (GO:1902667)2.79736937
107photoreceptor cell development (GO:0042461)2.79522184
108regulation of synapse organization (GO:0050807)2.79341228
109ATP hydrolysis coupled proton transport (GO:0015991)2.79180960
110energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.79180960
111cerebellar Purkinje cell differentiation (GO:0021702)2.78857299
112amino acid import (GO:0043090)2.78459402
113acrosome reaction (GO:0007340)2.76480768
114transmission of nerve impulse (GO:0019226)2.75262765
115reflex (GO:0060004)2.74315836
116regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.73616486
117regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.73616486
118positive regulation of amino acid transport (GO:0051957)2.72811564
119limb bud formation (GO:0060174)2.71048474
120trivalent inorganic cation transport (GO:0072512)2.70274815
121ferric iron transport (GO:0015682)2.70274815
122behavioral response to ethanol (GO:0048149)2.70005581
123negative regulation of appetite (GO:0032099)2.67910223
124negative regulation of response to food (GO:0032096)2.67910223
125otic vesicle formation (GO:0030916)2.67678928
126detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.67203412
127cerebral cortex radially oriented cell migration (GO:0021799)2.66180677
128central nervous system projection neuron axonogenesis (GO:0021952)2.64636224
129positive regulation of digestive system process (GO:0060456)2.62929654
130fat-soluble vitamin catabolic process (GO:0042363)2.60769926
131vitamin catabolic process (GO:0009111)2.60769926
132retinal ganglion cell axon guidance (GO:0031290)2.51801892
133long-term memory (GO:0007616)2.46519448
134establishment of protein localization to mitochondrial membrane (GO:0090151)2.46116994
135response to pheromone (GO:0019236)2.46070958
136kidney morphogenesis (GO:0060993)2.43584073
137negative regulation of axon extension involved in axon guidance (GO:0048843)2.43037837
138regulation of uterine smooth muscle contraction (GO:0070472)2.41786826
139hindbrain development (GO:0030902)2.40823442
140negative regulation of transcription regulatory region DNA binding (GO:2000678)2.40540340
141membrane assembly (GO:0071709)2.39593462
142water-soluble vitamin biosynthetic process (GO:0042364)2.39267314
143negative regulation of neurotransmitter transport (GO:0051589)2.38857511
144spinal cord motor neuron differentiation (GO:0021522)2.36112471
145forebrain neuron differentiation (GO:0021879)2.35497586
146protein localization to Golgi apparatus (GO:0034067)2.33625701
147synapse organization (GO:0050808)2.33493224
148thalamus development (GO:0021794)2.32870824
149positive regulation of meiosis (GO:0045836)2.32760882
150intraciliary transport (GO:0042073)2.32002616
151cellular response to cholesterol (GO:0071397)2.30700554
152neuromuscular synaptic transmission (GO:0007274)2.29090439
153vitamin D metabolic process (GO:0042359)2.28108828
154phosphate ion homeostasis (GO:0055062)2.27489712
155trivalent inorganic anion homeostasis (GO:0072506)2.27489712
156membrane depolarization during action potential (GO:0086010)2.27020340
157negative chemotaxis (GO:0050919)2.26488691
158forebrain neuron development (GO:0021884)2.26294503
159negative regulation of axon guidance (GO:1902668)2.25652017
160appendage development (GO:0048736)2.25469614
161limb development (GO:0060173)2.25469614
162spinal cord development (GO:0021510)2.25123958
163detection of mechanical stimulus involved in sensory perception (GO:0050974)2.23941541
164neuronal stem cell maintenance (GO:0097150)2.22868756
165brain morphogenesis (GO:0048854)2.22242668
166phosphorelay signal transduction system (GO:0000160)2.21979607
167adult behavior (GO:0030534)2.21136224
168central nervous system neuron axonogenesis (GO:0021955)2.20973619
169regulation of axon regeneration (GO:0048679)2.20413247
170regulation of neuron projection regeneration (GO:0070570)2.20413247

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human4.97425619
2EZH2_22144423_ChIP-Seq_EOC_Human4.09214103
3GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.53852378
4GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.74051048
5RBPJ_22232070_ChIP-Seq_NCS_Mouse2.68553332
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.67939463
7TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.64631323
8* TAF15_26573619_Chip-Seq_HEK293_Human2.64046762
9SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.55045914
10ZFP57_27257070_Chip-Seq_ESCs_Mouse2.52314700
11CTBP2_25329375_ChIP-Seq_LNCAP_Human2.49068741
12JARID2_20064375_ChIP-Seq_MESCs_Mouse2.47520125
13FUS_26573619_Chip-Seq_HEK293_Human2.40909691
14AR_21572438_ChIP-Seq_LNCaP_Human2.32251991
15CTBP1_25329375_ChIP-Seq_LNCAP_Human2.29091432
16EZH2_27304074_Chip-Seq_ESCs_Mouse2.28717300
17SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.24254781
18POU3F2_20337985_ChIP-ChIP_501MEL_Human2.18608904
19SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.14358698
20ZNF274_21170338_ChIP-Seq_K562_Hela2.13402295
21P300_19829295_ChIP-Seq_ESCs_Human2.13196436
22EED_16625203_ChIP-ChIP_MESCs_Mouse2.12763132
23JARID2_20075857_ChIP-Seq_MESCs_Mouse2.08982987
24RNF2_18974828_ChIP-Seq_MESCs_Mouse2.07815282
25EZH2_18974828_ChIP-Seq_MESCs_Mouse2.07815282
26* REST_21632747_ChIP-Seq_MESCs_Mouse2.07094000
27SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.01728027
28SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.01148884
29PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human2.00749142
30SMAD4_21799915_ChIP-Seq_A2780_Human2.00703928
31CBX2_27304074_Chip-Seq_ESCs_Mouse1.92809855
32BMI1_23680149_ChIP-Seq_NPCS_Mouse1.92451082
33SMAD_19615063_ChIP-ChIP_OVARY_Human1.89164048
34SALL1_21062744_ChIP-ChIP_HESCs_Human1.87217576
35ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.84427535
36* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.81867317
37RNF2_27304074_Chip-Seq_ESCs_Mouse1.81602944
38MTF2_20144788_ChIP-Seq_MESCs_Mouse1.80712615
39EZH2_27294783_Chip-Seq_ESCs_Mouse1.79161012
40CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.77947777
41PIAS1_25552417_ChIP-Seq_VCAP_Human1.76376226
42SMAD3_21741376_ChIP-Seq_EPCs_Human1.72379892
43SUZ12_27294783_Chip-Seq_ESCs_Mouse1.67321255
44SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.65316107
45RNF2_27304074_Chip-Seq_NSC_Mouse1.63261088
46IGF1R_20145208_ChIP-Seq_DFB_Human1.61827283
47* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.59617879
48OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.59568947
49NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.59243388
50CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.57129041
51PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.56650550
52ER_23166858_ChIP-Seq_MCF-7_Human1.52972133
53RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.51860574
54REST_18959480_ChIP-ChIP_MESCs_Mouse1.51186019
55AR_25329375_ChIP-Seq_VCAP_Human1.49916625
56EWS_26573619_Chip-Seq_HEK293_Human1.47999533
57PCGF2_27294783_Chip-Seq_NPCs_Mouse1.44596099
58SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.43855873
59DROSHA_22980978_ChIP-Seq_HELA_Human1.42986285
60CDX2_19796622_ChIP-Seq_MESCs_Mouse1.41473628
61STAT3_23295773_ChIP-Seq_U87_Human1.41061922
62* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.40686515
63AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.38979337
64NRF2_20460467_ChIP-Seq_MEFs_Mouse1.37810761
65NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.37810761
66TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.36445557
67TCF4_23295773_ChIP-Seq_U87_Human1.35918541
68CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.35804849
69NANOG_18555785_Chip-Seq_ESCs_Mouse1.35132449
70SOX2_21211035_ChIP-Seq_LN229_Gbm1.34781122
71EZH2_27294783_Chip-Seq_NPCs_Mouse1.32505949
72IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.31677880
73CBP_20019798_ChIP-Seq_JUKART_Human1.31677880
74VDR_22108803_ChIP-Seq_LS180_Human1.30566611
75TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.29962865
76P53_22127205_ChIP-Seq_FIBROBLAST_Human1.29163621
77RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.28712095
78PCGF2_27294783_Chip-Seq_ESCs_Mouse1.27290264
79TBX3_20139965_ChIP-Seq_MESCs_Mouse1.25582012
80FLI1_27457419_Chip-Seq_LIVER_Mouse1.25522260
81TP53_16413492_ChIP-PET_HCT116_Human1.24152024
82MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.23906591
83TBX3_20139965_ChIP-Seq_ESCs_Mouse1.23856530
84SOX9_26525672_Chip-Seq_HEART_Mouse1.23618527
85RUNX2_22187159_ChIP-Seq_PCA_Human1.22978505
86NFE2_27457419_Chip-Seq_LIVER_Mouse1.22740113
87E2F1_18555785_Chip-Seq_ESCs_Mouse1.22644541
88STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.22511557
89BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.21857337
90JUN_21703547_ChIP-Seq_K562_Human1.21716302
91EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.20845766
92TP53_18474530_ChIP-ChIP_U2OS_Human1.20065421
93POU5F1_16153702_ChIP-ChIP_HESCs_Human1.19880845
94TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18842655
95POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.18547340
96TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18547340
97PRDM14_20953172_ChIP-Seq_ESCs_Human1.18498209
98* KDM2B_26808549_Chip-Seq_REH_Human1.17910218
99TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.15862318
100YAP1_20516196_ChIP-Seq_MESCs_Mouse1.15521075
101VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.14403721
102KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.12620988
103IKZF1_21737484_ChIP-ChIP_HCT116_Human1.12333412
104FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.11056182
105ARNT_22903824_ChIP-Seq_MCF-7_Human1.10635036
106MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.10453497
107HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.10410180
108P53_22387025_ChIP-Seq_ESCs_Mouse1.10245677
109MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.09780282
110RARB_27405468_Chip-Seq_BRAIN_Mouse1.09388693
111TCF4_22108803_ChIP-Seq_LS180_Human1.09330733
112SUZ12_18555785_Chip-Seq_ESCs_Mouse1.09021912
113SUZ12_27294783_Chip-Seq_NPCs_Mouse1.08853330
114TAL1_26923725_Chip-Seq_HPCs_Mouse1.08718439
115NR3C1_21868756_ChIP-Seq_MCF10A_Human1.08690405
116CMYC_18555785_Chip-Seq_ESCs_Mouse1.08418895
117RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.08337527
118BCAT_22108803_ChIP-Seq_LS180_Human1.06436977
119CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.04538888
120ZNF217_24962896_ChIP-Seq_MCF-7_Human1.03999125
121LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02546555
122STAT3_18555785_Chip-Seq_ESCs_Mouse1.02209163
123AR_19668381_ChIP-Seq_PC3_Human1.01898310
124TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.00343373

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.14936288
2MP0003136_yellow_coat_color3.92034920
3MP0005171_absent_coat_pigmentation3.46290046
4MP0009046_muscle_twitch3.20971221
5MP0004859_abnormal_synaptic_plasticity2.90294732
6MP0003635_abnormal_synaptic_transmissio2.89798096
7MP0001188_hyperpigmentation2.75317171
8MP0009745_abnormal_behavioral_response2.55516116
9MP0002064_seizures2.54684694
10MP0001984_abnormal_olfaction2.54284543
11MP0005551_abnormal_eye_electrophysiolog2.53884290
12MP0002063_abnormal_learning/memory/cond2.50203381
13MP0001486_abnormal_startle_reflex2.46786963
14MP0002572_abnormal_emotion/affect_behav2.33280437
15MP0001968_abnormal_touch/_nociception2.32519551
16MP0005423_abnormal_somatic_nervous2.28842157
17MP0002736_abnormal_nociception_after2.25037050
18MP0003787_abnormal_imprinting2.09577413
19MP0002067_abnormal_sensory_capabilities2.06372559
20MP0005646_abnormal_pituitary_gland2.06072295
21MP0002272_abnormal_nervous_system2.02907792
22MP0003890_abnormal_embryonic-extraembry1.98258799
23MP0002822_catalepsy1.95697621
24MP0002734_abnormal_mechanical_nocicepti1.95448798
25MP0002557_abnormal_social/conspecific_i1.80067394
26MP0004270_analgesia1.76762627
27MP0000778_abnormal_nervous_system1.75432061
28MP0002184_abnormal_innervation1.71855138
29MP0002938_white_spotting1.66947044
30MP0006292_abnormal_olfactory_placode1.62668438
31MP0003122_maternal_imprinting1.58670751
32MP0001440_abnormal_grooming_behavior1.58293332
33MP0001542_abnormal_bone_strength1.56439901
34MP0001502_abnormal_circadian_rhythm1.55510687
35MP0002735_abnormal_chemical_nociception1.49547237
36MP0010386_abnormal_urinary_bladder1.48938849
37MP0001501_abnormal_sleep_pattern1.45192793
38MP0004142_abnormal_muscle_tone1.45013629
39MP0000631_abnormal_neuroendocrine_gland1.44672869
40MP0003937_abnormal_limbs/digits/tail_de1.42688734
41MP0001529_abnormal_vocalization1.40622550
42MP0002090_abnormal_vision1.39611647
43MP0005084_abnormal_gallbladder_morpholo1.39514783
44MP0005386_behavior/neurological_phenoty1.38043420
45MP0004924_abnormal_behavior1.38043420
46MP0006276_abnormal_autonomic_nervous1.37800573
47MP0009780_abnormal_chondrocyte_physiolo1.36217087
48MP0006072_abnormal_retinal_apoptosis1.35866136
49MP0002882_abnormal_neuron_morphology1.34972442
50MP0009250_abnormal_appendicular_skeleto1.33814208
51MP0001986_abnormal_taste_sensitivity1.33437591
52MP0004233_abnormal_muscle_weight1.33157447
53MP0005499_abnormal_olfactory_system1.32982375
54MP0005394_taste/olfaction_phenotype1.32982375
55MP0003879_abnormal_hair_cell1.32567668
56MP0002751_abnormal_autonomic_nervous1.31393562
57MP0003123_paternal_imprinting1.30972345
58MP0002876_abnormal_thyroid_physiology1.30409863
59MP0000049_abnormal_middle_ear1.29407223
60MP0002277_abnormal_respiratory_mucosa1.28559747
61MP0004858_abnormal_nervous_system1.28477002
62MP0002697_abnormal_eye_size1.28037675
63MP0002638_abnormal_pupillary_reflex1.27779601
64MP0001970_abnormal_pain_threshold1.27535090
65MP0002233_abnormal_nose_morphology1.27459343
66MP0005253_abnormal_eye_physiology1.26129370
67MP0008569_lethality_at_weaning1.25198818
68MP0001963_abnormal_hearing_physiology1.23425292
69MP0002752_abnormal_somatic_nervous1.18117952
70MP0002837_dystrophic_cardiac_calcinosis1.17647204
71MP0002229_neurodegeneration1.15974619
72MP0005409_darkened_coat_color1.15277866
73MP0001664_abnormal_digestion1.15069187
74MP0004742_abnormal_vestibular_system1.14729359
75MP0002102_abnormal_ear_morphology1.13829980
76MP0004811_abnormal_neuron_physiology1.10937207
77MP0005645_abnormal_hypothalamus_physiol1.10849658
78MP0002733_abnormal_thermal_nociception1.09334407
79MP0001299_abnormal_eye_distance/1.08753813
80MP0004133_heterotaxia1.08336943
81MP0002066_abnormal_motor_capabilities/c1.07753033
82MP0000955_abnormal_spinal_cord1.06200753
83MP0000026_abnormal_inner_ear1.06034529
84MP0005187_abnormal_penis_morphology1.05871075
85MP0009697_abnormal_copulation1.05812718
86MP0002909_abnormal_adrenal_gland1.05795582
87MP0003119_abnormal_digestive_system1.04996600
88MP0001286_abnormal_eye_development1.03908229
89MP0003121_genomic_imprinting1.03894884
90MP0000569_abnormal_digit_pigmentation1.03067693
91MP0003755_abnormal_palate_morphology1.01087023
92MP0002152_abnormal_brain_morphology1.00126412
93MP0008789_abnormal_olfactory_epithelium0.99746965
94MP0005195_abnormal_posterior_eye0.99202243
95MP0001905_abnormal_dopamine_level0.98501328
96MP0002653_abnormal_ependyma_morphology0.97991280
97MP0005248_abnormal_Harderian_gland0.97294630
98MP0000751_myopathy0.97114474
99MP0001879_abnormal_lymphatic_vessel0.96199067
100MP0002160_abnormal_reproductive_system0.94431546
101MP0004215_abnormal_myocardial_fiber0.91028917
102MP0003861_abnormal_nervous_system0.90275931
103MP0003283_abnormal_digestive_organ0.89987260
104MP0003183_abnormal_peptide_metabolism0.88819269
105MP0004134_abnormal_chest_morphology0.86812683
106MP0005503_abnormal_tendon_morphology0.86678055
107MP0001177_atelectasis0.86643525
108MP0001293_anophthalmia0.86265159
109MP0001346_abnormal_lacrimal_gland0.86252871
110MP0003938_abnormal_ear_development0.83296684
111MP0004885_abnormal_endolymph0.82963456
112MP0002928_abnormal_bile_duct0.82661995
113MP0003634_abnormal_glial_cell0.82261384
114MP0003935_abnormal_craniofacial_develop0.82183694
115MP0001270_distended_abdomen0.81479683
116MP0003385_abnormal_body_wall0.79971583
117MP0003942_abnormal_urinary_system0.79677929
118MP0003941_abnormal_skin_development0.78468647
119MP0000428_abnormal_craniofacial_morphol0.78055013
120MP0003646_muscle_fatigue0.77806030
121MP0001324_abnormal_eye_pigmentation0.76679613
122MP0003633_abnormal_nervous_system0.76287119
123MP0005174_abnormal_tail_pigmentation0.74786689
124MP0003631_nervous_system_phenotype0.74633512
125MP0000647_abnormal_sebaceous_gland0.74598110
126MP0002116_abnormal_craniofacial_bone0.73089000
127MP0002069_abnormal_eating/drinking_beha0.72536011
128MP0008260_abnormal_autophagy0.72498198
129MP0004782_abnormal_surfactant_physiolog0.72078790
130MP0001485_abnormal_pinna_reflex0.71898086
131MP0008877_abnormal_DNA_methylation0.71592814
132MP0002095_abnormal_skin_pigmentation0.70840452
133MP0000566_synostosis0.70437373
134MP0004085_abnormal_heartbeat0.70419515
135MP0003632_abnormal_nervous_system0.69894764

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.69274307
2Congenital stationary night blindness (HP:0007642)5.67938422
3Epileptic encephalopathy (HP:0200134)5.66706797
4Febrile seizures (HP:0002373)5.44326577
5Atonic seizures (HP:0010819)4.31673159
6Osteomalacia (HP:0002749)3.91224244
7Absence seizures (HP:0002121)3.89145717
8Gait imbalance (HP:0002141)3.86424035
9Hyperventilation (HP:0002883)3.72146501
10Abnormal hair whorl (HP:0010721)3.69205729
11Congenital primary aphakia (HP:0007707)3.57833537
12Medial flaring of the eyebrow (HP:0010747)3.41556721
13Dialeptic seizures (HP:0011146)3.41504697
14Nephrogenic diabetes insipidus (HP:0009806)3.35918229
15Progressive cerebellar ataxia (HP:0002073)3.33234331
16Focal seizures (HP:0007359)3.31549085
17Blue irides (HP:0000635)3.29336062
18Narrow nasal bridge (HP:0000446)3.10685327
19Severe visual impairment (HP:0001141)3.09956652
20True hermaphroditism (HP:0010459)2.91244861
21White forelock (HP:0002211)2.89233602
22Poor coordination (HP:0002370)2.84329692
23Generalized tonic-clonic seizures (HP:0002069)2.84245187
24Vaginal atresia (HP:0000148)2.77405943
25Abnormality of the labia minora (HP:0012880)2.75117580
26Genital tract atresia (HP:0001827)2.74603131
27Septo-optic dysplasia (HP:0100842)2.72026867
28Nephronophthisis (HP:0000090)2.64122519
29Patchy hypopigmentation of hair (HP:0011365)2.62094212
30Abnormality of the dental pulp (HP:0006479)2.60137933
31Absent speech (HP:0001344)2.59404827
32Morphological abnormality of the middle ear (HP:0008609)2.59386379
33Abnormality of renal resorption (HP:0011038)2.57023072
34Acute necrotizing encephalopathy (HP:0006965)2.49622844
35Abnormality of the dental root (HP:0006486)2.48908524
36Taurodontia (HP:0000679)2.48908524
37Abnormality of permanent molar morphology (HP:0011071)2.48908524
38Polyphagia (HP:0002591)2.47770191
39Central scotoma (HP:0000603)2.46601484
40Specific learning disability (HP:0001328)2.45247684
41Aplasia/Hypoplasia of the fovea (HP:0008060)2.43587607
42Hypoplasia of the fovea (HP:0007750)2.43587607
43Generalized hypopigmentation (HP:0007513)2.43258313
44Broad-based gait (HP:0002136)2.40663159
45Abnormal mitochondria in muscle tissue (HP:0008316)2.38667098
46Abnormality of molar morphology (HP:0011070)2.38267569
47Abnormality of molar (HP:0011077)2.38267569
48Neuroendocrine neoplasm (HP:0100634)2.35762651
49Protruding tongue (HP:0010808)2.32351259
50Drooling (HP:0002307)2.31497797
51Excessive salivation (HP:0003781)2.31497797
52Visual hallucinations (HP:0002367)2.31376376
53Optic nerve hypoplasia (HP:0000609)2.30809032
54Pancreatic fibrosis (HP:0100732)2.30257626
55Progressive macrocephaly (HP:0004481)2.29451147
56Abnormality of macular pigmentation (HP:0008002)2.28196295
57Hemiparesis (HP:0001269)2.27583085
58Intestinal atresia (HP:0011100)2.27068726
59Myokymia (HP:0002411)2.26723537
60Epileptiform EEG discharges (HP:0011182)2.25521583
61Decreased central vision (HP:0007663)2.24422777
62Megalencephaly (HP:0001355)2.23534609
63Abnormality of the renal medulla (HP:0100957)2.21825710
64Aplasia/Hypoplasia of the lens (HP:0008063)2.21824823
65Action tremor (HP:0002345)2.21008594
66Gaze-evoked nystagmus (HP:0000640)2.20502530
67Inability to walk (HP:0002540)2.18139266
68Hypoplastic left heart (HP:0004383)2.15954445
69Abnormality of midbrain morphology (HP:0002418)2.15711144
70Molar tooth sign on MRI (HP:0002419)2.15711144
71EEG with generalized epileptiform discharges (HP:0011198)2.14561213
72Cortical dysplasia (HP:0002539)2.12772000
73Abnormality of the pons (HP:0007361)2.11289861
74Optic disc pallor (HP:0000543)2.07441942
75Genetic anticipation (HP:0003743)2.05021011
76Pheochromocytoma (HP:0002666)2.04039621
77Albinism (HP:0001022)2.00370427
78Abnormality of the ischium (HP:0003174)2.00087130
79Absent eyebrow (HP:0002223)1.99096704
80Long foot (HP:0001833)1.98857783
81Growth hormone deficiency (HP:0000824)1.98565285
82Hypoplasia of the pons (HP:0012110)1.98379733
83Occipital encephalocele (HP:0002085)1.97857297
84Dysdiadochokinesis (HP:0002075)1.97694645
85Heterochromia iridis (HP:0001100)1.94087257
86Scrotal hypoplasia (HP:0000046)1.92030770
87Short foot (HP:0001773)1.92030361
88Abnormal eating behavior (HP:0100738)1.91033606
89Lissencephaly (HP:0001339)1.90423695
90Neonatal short-limb short stature (HP:0008921)1.90406153
91Labial hypoplasia (HP:0000066)1.89436626
92Congenital sensorineural hearing impairment (HP:0008527)1.89217380
93Renal Fanconi syndrome (HP:0001994)1.87379128
94Aplasia involving bones of the upper limbs (HP:0009823)1.86376762
95Aplasia of the phalanges of the hand (HP:0009802)1.86376762
96Aplasia involving bones of the extremities (HP:0009825)1.86376762
97Abnormality of binocular vision (HP:0011514)1.85113254
98Diplopia (HP:0000651)1.85113254
99Abnormal auditory evoked potentials (HP:0006958)1.84474438
100Submucous cleft hard palate (HP:0000176)1.83948455
101Fibular hypoplasia (HP:0003038)1.83061761
102Abnormal rod and cone electroretinograms (HP:0008323)1.82700285
103Midline defect of the nose (HP:0004122)1.81685179
104Absent septum pellucidum (HP:0001331)1.81405144
105Progressive inability to walk (HP:0002505)1.80711200
106Abnormality of the fovea (HP:0000493)1.80578169
107Hypoplastic labia majora (HP:0000059)1.80485608
108Pancreatic cysts (HP:0001737)1.79656040
109Poor suck (HP:0002033)1.79375827
110Brushfield spots (HP:0001088)1.77910524
111Mitochondrial inheritance (HP:0001427)1.77901124
112Anophthalmia (HP:0000528)1.76945283
113Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.75297191
114Aplasia/Hypoplasia of the tongue (HP:0010295)1.74758662
115Metaphyseal dysplasia (HP:0100255)1.73955522
116Bifid tongue (HP:0010297)1.73893945
117Hypsarrhythmia (HP:0002521)1.73610793
118Anencephaly (HP:0002323)1.73198301
119Hypoplastic heart (HP:0001961)1.72973251
120Esotropia (HP:0000565)1.72777553
121Short tibia (HP:0005736)1.70186115
122Abnormality of the septum pellucidum (HP:0007375)1.69631371
123Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.69594861
124Aganglionic megacolon (HP:0002251)1.69381742
125Abnormality of dentin (HP:0010299)1.69361323
126Postaxial hand polydactyly (HP:0001162)1.68648989
127Enlarged penis (HP:0000040)1.68260613
128Truncal ataxia (HP:0002078)1.68066220
129Mutism (HP:0002300)1.67986189
130Preaxial foot polydactyly (HP:0001841)1.67580051
131Broad foot (HP:0001769)1.67532840
132Leukodystrophy (HP:0002415)1.66905800
133Fair hair (HP:0002286)1.66517040
134Postaxial foot polydactyly (HP:0001830)1.66346643
135Cupped ear (HP:0000378)1.65456086
136Limb dystonia (HP:0002451)1.65316750
137Hemiplegia (HP:0002301)1.65305070
138Acute encephalopathy (HP:0006846)1.65190101
139Ulnar claw (HP:0001178)1.64809656
140Aplasia/Hypoplasia of the tibia (HP:0005772)1.64385179
141Astigmatism (HP:0000483)1.64196602
142Hypoventilation (HP:0002791)1.62881119
143Scanning speech (HP:0002168)1.62492443
144Hypoplastic female external genitalia (HP:0012815)1.59520272
145Agitation (HP:0000713)1.59162737
146Abnormality of the labia majora (HP:0012881)1.58764442
147Gastrointestinal atresia (HP:0002589)1.58722222
148Exotropia (HP:0000577)1.58414079
149Preaxial hand polydactyly (HP:0001177)1.57337907
150Congenital, generalized hypertrichosis (HP:0004540)1.56971181
151Abnormality of the renal cortex (HP:0011035)1.54577886
152Abnormal urine phosphate concentration (HP:0012599)1.54526813

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK7.12502082
2MAP2K73.58838584
3AKT33.53485039
4MAP3K43.39904587
5MARK12.63295701
6STK392.40732457
7MAPK132.38701456
8TNIK2.33324663
9CDK82.26149585
10WNK42.08696104
11CCNB12.03118962
12NTRK22.00949665
13STK242.00108497
14PLK21.95560917
15NTRK31.91917220
16SGK21.88299972
17MAP3K121.83230172
18EPHA41.74487136
19SIK31.66442925
20ACVR1B1.63518028
21MINK11.63249771
22PRPF4B1.49969738
23PRKD31.47635043
24SGK4941.46019474
25SGK2231.46019474
26YES11.42377066
27STK38L1.40714385
28TRIM281.38814419
29PHKG21.36563147
30PHKG11.36563147
31ERBB31.28265103
32NUAK11.24680712
33NME11.21122099
34MAP2K41.20037055
35BRAF1.19378930
36MKNK21.18559986
37MUSK1.10408639
38TSSK61.10024328
39DYRK1A1.07266278
40CSNK1G21.06785759
41FES1.05103523
42TGFBR11.04651856
43DAPK11.03069050
44PRKCE1.02417018
45PRKCG1.02168355
46SGK31.00656189
47CSNK1G10.98634185
48WNK30.98179179
49CDK30.96881651
50DAPK20.93576296
51ARAF0.92946853
52CDC70.90821302
53MAP3K90.90403713
54PAK30.86870921
55DYRK20.84231217
56CAMK2A0.83809728
57KSR10.83753255
58ERBB40.83619689
59IRAK20.83457539
60TAOK10.80425040
61MAP3K60.79810078
62FGFR20.79631379
63SIK20.78642560
64PKN10.78445500
65PBK0.78353895
66WNK10.77745393
67ADRBK20.76946229
68GRK50.76140577
69MAP3K130.74277924
70INSRR0.74240921
71CDK50.72263521
72PAK60.72218344
73TAF10.71317450
74CDK190.71061887
75STK30.70355936
76CSNK1A1L0.65568133
77PLK40.65350899
78SGK10.63074507
79EPHB20.61948175
80MAPK70.61132507
81LATS10.60350667
82BRD40.58049453
83OXSR10.57161439
84IRAK10.57076667
85BRSK20.56369155
86NEK60.56050020
87BMPR20.55921952
88MYLK0.55301086
89MKNK10.54740105
90CSNK1G30.53168341
91NLK0.51995122
92EPHA30.50745253
93RPS6KA40.50604954
94STK160.50475830
95FGFR10.50242703
96CAMK2D0.49387826
97MAP4K20.48947094
98DMPK0.48777952
99ADRBK10.48493381
100TYRO30.48264611
101ROCK20.47930664
102BMPR1B0.47751427
103NTRK10.47122530
104STK380.46878142
105GRK10.45886687
106PLK30.44747508
107LMTK20.44631738
108FRK0.43465839
109PRKG10.43401096
110PNCK0.42078299
111CDK180.41381514
112CSNK1D0.41218882
113BCR0.41181402
114CDK140.40376998
115ROCK10.40320376
116DYRK30.40098011
117MAPKAPK30.39864363
118RPS6KB10.39595203
119PRKACA0.39153910
120ZAK0.38916978
121CAMK2B0.38726092
122PTK2B0.38600960
123CSNK1A10.37121500
124STK110.37086216
125MAPKAPK50.36557675
126MAPK120.35326974
127PINK10.34673732
128ABL20.34517839
129CAMK10.34484938
130GSK3A0.34119583
131PRKCZ0.33820012
132CAMK1G0.33795877
133CDK150.33500124
134PDK40.33188512
135PDK30.33188512
136FER0.32342543
137RPS6KA30.31812380
138PRKCB0.31283099
139BCKDK0.30669622
140CDK120.30624354
141RPS6KA20.30115884
142PIK3CA0.29864776
143PRKCA0.29508472
144UHMK10.29479777
145PRKACB0.28678424
146GSK3B0.27986833

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.95735177
2Synaptic vesicle cycle_Homo sapiens_hsa047213.88340777
3GABAergic synapse_Homo sapiens_hsa047273.38455209
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047233.21755842
5Morphine addiction_Homo sapiens_hsa050323.06387509
6Collecting duct acid secretion_Homo sapiens_hsa049662.97751361
7Circadian entrainment_Homo sapiens_hsa047132.57572102
8Olfactory transduction_Homo sapiens_hsa047402.44400150
9Glutamatergic synapse_Homo sapiens_hsa047242.17150571
10Phototransduction_Homo sapiens_hsa047442.01554198
11Serotonergic synapse_Homo sapiens_hsa047261.95426240
12Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.92132044
13Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.87870633
14Butanoate metabolism_Homo sapiens_hsa006501.83003828
15Taste transduction_Homo sapiens_hsa047421.82685713
16Insulin secretion_Homo sapiens_hsa049111.78085297
17Dopaminergic synapse_Homo sapiens_hsa047281.75620597
18Protein export_Homo sapiens_hsa030601.73582998
19Vibrio cholerae infection_Homo sapiens_hsa051101.72775301
20Salivary secretion_Homo sapiens_hsa049701.72386139
21Oxidative phosphorylation_Homo sapiens_hsa001901.64542544
22Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.58918570
23Renin secretion_Homo sapiens_hsa049241.53405662
24Calcium signaling pathway_Homo sapiens_hsa040201.51655145
25Long-term depression_Homo sapiens_hsa047301.51528382
26Cholinergic synapse_Homo sapiens_hsa047251.50862452
27Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.44647233
28Amphetamine addiction_Homo sapiens_hsa050311.44404036
29Sulfur metabolism_Homo sapiens_hsa009201.40125290
30Circadian rhythm_Homo sapiens_hsa047101.38097773
31Long-term potentiation_Homo sapiens_hsa047201.37428361
32Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.29540839
33Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.24909336
34Vitamin B6 metabolism_Homo sapiens_hsa007501.21717724
35Maturity onset diabetes of the young_Homo sapiens_hsa049501.19795059
36Propanoate metabolism_Homo sapiens_hsa006401.19754699
37Oxytocin signaling pathway_Homo sapiens_hsa049211.19097545
38Steroid biosynthesis_Homo sapiens_hsa001001.17785806
39Dorso-ventral axis formation_Homo sapiens_hsa043201.15175350
40Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.15146478
41Basal transcription factors_Homo sapiens_hsa030221.14883051
42Gap junction_Homo sapiens_hsa045401.14480266
43Axon guidance_Homo sapiens_hsa043601.14337367
44Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.14158313
45Nitrogen metabolism_Homo sapiens_hsa009101.12391929
46Selenocompound metabolism_Homo sapiens_hsa004501.10880958
47Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.09887320
48Hippo signaling pathway_Homo sapiens_hsa043901.07716036
49Cardiac muscle contraction_Homo sapiens_hsa042601.06718287
50Gastric acid secretion_Homo sapiens_hsa049711.05318065
51Parkinsons disease_Homo sapiens_hsa050121.04950155
52alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.03496369
53Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.02643817
54Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.01071798
55Aldosterone synthesis and secretion_Homo sapiens_hsa049251.00870000
56Alzheimers disease_Homo sapiens_hsa050101.00088834
57Rheumatoid arthritis_Homo sapiens_hsa053230.99299680
58Linoleic acid metabolism_Homo sapiens_hsa005910.96113572
59Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.95682626
60TGF-beta signaling pathway_Homo sapiens_hsa043500.95084125
61cGMP-PKG signaling pathway_Homo sapiens_hsa040220.94524527
62Cocaine addiction_Homo sapiens_hsa050300.94412725
63Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.93050800
64Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.92037560
65Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.91810831
66cAMP signaling pathway_Homo sapiens_hsa040240.89178442
67Dilated cardiomyopathy_Homo sapiens_hsa054140.87591420
68Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.84699172
69Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.82822373
70Vascular smooth muscle contraction_Homo sapiens_hsa042700.81408918
71Huntingtons disease_Homo sapiens_hsa050160.81345942
72Tryptophan metabolism_Homo sapiens_hsa003800.79423830
73ErbB signaling pathway_Homo sapiens_hsa040120.77032601
74Melanogenesis_Homo sapiens_hsa049160.76625898
75SNARE interactions in vesicular transport_Homo sapiens_hsa041300.76561136
76ABC transporters_Homo sapiens_hsa020100.76428229
77GnRH signaling pathway_Homo sapiens_hsa049120.74325290
78Phagosome_Homo sapiens_hsa041450.74148549
79Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.74130675
80Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.71957930
81Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.70882962
82Folate biosynthesis_Homo sapiens_hsa007900.69421378
83Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.69277305
84Melanoma_Homo sapiens_hsa052180.66145085
85Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.64556568
86Peroxisome_Homo sapiens_hsa041460.63659543
87MAPK signaling pathway_Homo sapiens_hsa040100.63077779
88Phosphatidylinositol signaling system_Homo sapiens_hsa040700.60805622
89Type II diabetes mellitus_Homo sapiens_hsa049300.58883636
90Fanconi anemia pathway_Homo sapiens_hsa034600.57540692
91Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.57164586
92Wnt signaling pathway_Homo sapiens_hsa043100.56925743
93Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.56489961
94Colorectal cancer_Homo sapiens_hsa052100.55426036
95Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.54815282
96Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.53603575
97Type I diabetes mellitus_Homo sapiens_hsa049400.53158180
98Ras signaling pathway_Homo sapiens_hsa040140.53119584
99Glioma_Homo sapiens_hsa052140.48949707
100Fructose and mannose metabolism_Homo sapiens_hsa000510.48857614
101Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.47489504
102Homologous recombination_Homo sapiens_hsa034400.47039872
103Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.46143128
104RNA polymerase_Homo sapiens_hsa030200.45402339
105Tight junction_Homo sapiens_hsa045300.45386351
106Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.44864828
107Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.44200015
108Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.43848276
109Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.43830836
110Endometrial cancer_Homo sapiens_hsa052130.43727582
111Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.43086433
112Thyroid hormone signaling pathway_Homo sapiens_hsa049190.42985526
113Ovarian steroidogenesis_Homo sapiens_hsa049130.42811222
114Alcoholism_Homo sapiens_hsa050340.42028116
115Inositol phosphate metabolism_Homo sapiens_hsa005620.40047780
116Hedgehog signaling pathway_Homo sapiens_hsa043400.37573483
117Ether lipid metabolism_Homo sapiens_hsa005650.36609315
118Choline metabolism in cancer_Homo sapiens_hsa052310.34423920
119Estrogen signaling pathway_Homo sapiens_hsa049150.33255791
120Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.33107430
121Pancreatic secretion_Homo sapiens_hsa049720.31992502
122Thyroid hormone synthesis_Homo sapiens_hsa049180.29461325
123Oocyte meiosis_Homo sapiens_hsa041140.29434766
124Rap1 signaling pathway_Homo sapiens_hsa040150.28879461
125Sphingolipid metabolism_Homo sapiens_hsa006000.27153072
126Fatty acid biosynthesis_Homo sapiens_hsa000610.25798265
127Glucagon signaling pathway_Homo sapiens_hsa049220.25604942
128Basal cell carcinoma_Homo sapiens_hsa052170.24295541
129Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.21712954
130Phospholipase D signaling pathway_Homo sapiens_hsa040720.20732228
131Mineral absorption_Homo sapiens_hsa049780.20065389
132Regulation of autophagy_Homo sapiens_hsa041400.16732316
133Purine metabolism_Homo sapiens_hsa002300.15393527
134Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.14705499

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