FAM184A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium or flagellum-dependent cell motility (GO:0001539)5.80562377
2axonemal dynein complex assembly (GO:0070286)5.29691127
3cilium movement (GO:0003341)5.16435798
4neuron cell-cell adhesion (GO:0007158)4.78221132
5regulation of short-term neuronal synaptic plasticity (GO:0048172)4.69477569
6epithelial cilium movement (GO:0003351)4.53211554
7positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.40677836
8vocalization behavior (GO:0071625)4.38838692
9motile cilium assembly (GO:0044458)4.30419316
10homocysteine metabolic process (GO:0050667)4.23379291
11synaptic vesicle exocytosis (GO:0016079)4.21872704
12epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.07803335
13positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.87223795
14glutamate secretion (GO:0014047)3.84850670
15regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.81549521
16protein localization to cilium (GO:0061512)3.80238849
17synaptic vesicle maturation (GO:0016188)3.76927517
18intraciliary transport (GO:0042073)3.76210887
19ionotropic glutamate receptor signaling pathway (GO:0035235)3.75666835
20microtubule nucleation (GO:0007020)3.73197091
21ventricular system development (GO:0021591)3.70342938
22glutamate receptor signaling pathway (GO:0007215)3.69537650
23locomotory exploration behavior (GO:0035641)3.60951750
24gamma-aminobutyric acid transport (GO:0015812)3.60371026
25presynaptic membrane assembly (GO:0097105)3.60235573
26regulation of cilium movement (GO:0003352)3.59836175
27G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.58321084
28regulation of synaptic vesicle exocytosis (GO:2000300)3.56036742
29startle response (GO:0001964)3.54175207
30synaptic transmission, glutamatergic (GO:0035249)3.53115764
31regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.52863247
32protein localization to synapse (GO:0035418)3.49019610
33neuron-neuron synaptic transmission (GO:0007270)3.45258050
34cochlea development (GO:0090102)3.44380467
35acrosome reaction (GO:0007340)3.42900232
36neurotransmitter secretion (GO:0007269)3.38429290
37axoneme assembly (GO:0035082)3.36683624
38regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.36644413
39membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.35154549
40postsynaptic membrane organization (GO:0001941)3.34077797
41regulation of glutamate receptor signaling pathway (GO:1900449)3.33856447
42regulation of synaptic vesicle transport (GO:1902803)3.33615710
43synaptic vesicle endocytosis (GO:0048488)3.31924341
44tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.30474663
45RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.30474663
46cysteine metabolic process (GO:0006534)3.29082770
47calcium ion-dependent exocytosis (GO:0017156)3.29003791
48regulation of long-term neuronal synaptic plasticity (GO:0048169)3.28441515
49epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)3.24823437
50presynaptic membrane organization (GO:0097090)3.24624500
51microtubule severing (GO:0051013)3.24567584
52neurotransmitter-gated ion channel clustering (GO:0072578)3.24398434
53L-serine metabolic process (GO:0006563)3.24355461
54transmission of nerve impulse (GO:0019226)3.23787308
55righting reflex (GO:0060013)3.22419369
56inner ear receptor cell development (GO:0060119)3.22093223
57cilium assembly (GO:0042384)3.19606090
58regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.19545624
59cilium organization (GO:0044782)3.18496160
60auditory behavior (GO:0031223)3.17789489
61neuronal action potential propagation (GO:0019227)3.17044644
62regulation of neuronal synaptic plasticity (GO:0048168)3.16634089
63membrane depolarization during action potential (GO:0086010)3.15431756
64sperm motility (GO:0030317)3.15012536
65cerebellar Purkinje cell differentiation (GO:0021702)3.14058905
66chromatin remodeling at centromere (GO:0031055)3.13227778
67regulation of vesicle fusion (GO:0031338)3.11731443
68nonmotile primary cilium assembly (GO:0035058)3.11566396
69neurotransmitter transport (GO:0006836)3.11167227
70striatum development (GO:0021756)3.10823582
71CENP-A containing nucleosome assembly (GO:0034080)3.09897559
72exploration behavior (GO:0035640)3.08465569
73dopamine biosynthetic process (GO:0042416)3.07767181
74negative regulation of keratinocyte proliferation (GO:0010839)3.07354091
75folic acid-containing compound biosynthetic process (GO:0009396)3.07157728
76cellular potassium ion homeostasis (GO:0030007)3.04575889
77protein-chromophore linkage (GO:0018298)3.04014012
78response to auditory stimulus (GO:0010996)3.03887391
79long-term memory (GO:0007616)3.03742126
80negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.03702960
81dopamine transport (GO:0015872)3.03437879
82sulfur amino acid catabolic process (GO:0000098)2.99942823
83calcium ion import (GO:0070509)2.99942782
84regulation of synaptic transmission, glutamatergic (GO:0051966)2.95184140
85negative regulation of synaptic transmission, GABAergic (GO:0032229)2.92449672
86negative regulation of neurotransmitter transport (GO:0051589)2.92155905
87synapse assembly (GO:0007416)2.91674778
88otic vesicle formation (GO:0030916)2.91546112
89response to histamine (GO:0034776)2.91465991
90prepulse inhibition (GO:0060134)2.90629236
91histone exchange (GO:0043486)2.89630553
92regulation of respiratory system process (GO:0044065)2.89492939
93dendritic spine morphogenesis (GO:0060997)2.89108006
94neuron recognition (GO:0008038)2.88857589
95innervation (GO:0060384)2.88804374
96acrosome assembly (GO:0001675)2.88004872
97membrane hyperpolarization (GO:0060081)2.87807637
98cilium morphogenesis (GO:0060271)2.86922301
99adult walking behavior (GO:0007628)2.86079167
100positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.85666424
101behavioral defense response (GO:0002209)2.85614595
102behavioral fear response (GO:0001662)2.85614595
103positive regulation of dendritic spine morphogenesis (GO:0061003)2.85424570
104fusion of sperm to egg plasma membrane (GO:0007342)2.85241851
105behavioral response to nicotine (GO:0035095)2.84934018
106behavioral response to ethanol (GO:0048149)2.83336936
107regulation of plasminogen activation (GO:0010755)2.83049614
108gamma-aminobutyric acid signaling pathway (GO:0007214)2.82804316
109negative regulation of cytosolic calcium ion concentration (GO:0051481)2.82754440
110regulation of neurotransmitter levels (GO:0001505)2.81707497
111detection of calcium ion (GO:0005513)2.80775993
112positive regulation of membrane potential (GO:0045838)2.80196114
113multicellular organism reproduction (GO:0032504)2.78238088
114regulation of synapse structural plasticity (GO:0051823)2.75310279
115mating behavior (GO:0007617)2.74606017
116negative regulation of DNA-dependent DNA replication (GO:2000104)2.74544668
117mechanosensory behavior (GO:0007638)2.74517399
118synaptic vesicle docking involved in exocytosis (GO:0016081)2.73879180
119primary amino compound metabolic process (GO:1901160)2.70976451
120behavioral response to cocaine (GO:0048148)2.70553407
121negative regulation of DNA biosynthetic process (GO:2000279)2.70442739
122kinetochore organization (GO:0051383)2.69159492
123regulation of respiratory gaseous exchange (GO:0043576)2.69151031
124regulation of calcium ion-dependent exocytosis (GO:0017158)2.68969281
125heme transport (GO:0015886)2.68909950
126regulation of excitatory postsynaptic membrane potential (GO:0060079)2.67123662
127synaptic vesicle transport (GO:0048489)2.66744822
128establishment of synaptic vesicle localization (GO:0097480)2.66744822
129adenosine metabolic process (GO:0046085)2.62755498
130C4-dicarboxylate transport (GO:0015740)2.60468455
131pyrimidine nucleobase catabolic process (GO:0006208)2.57469153
132serine family amino acid catabolic process (GO:0009071)2.57086082
133DNA replication-independent nucleosome assembly (GO:0006336)2.55710000
134DNA replication-independent nucleosome organization (GO:0034724)2.55710000
135centriole replication (GO:0007099)2.55482010
136atrial cardiac muscle cell action potential (GO:0086014)2.50277611
137fear response (GO:0042596)2.49625482
138kinetochore assembly (GO:0051382)2.49267514
139histone H4-K12 acetylation (GO:0043983)2.48370998
140DNA double-strand break processing (GO:0000729)2.46651023
141somite rostral/caudal axis specification (GO:0032525)2.45265994
142cell migration involved in gastrulation (GO:0042074)2.40913758
143negative regulation of DNA recombination (GO:0045910)2.40688576
144DNA ligation (GO:0006266)2.36781623
145mitochondrial RNA metabolic process (GO:0000959)2.36211014
146single strand break repair (GO:0000012)2.35894597
147regulation of meiosis I (GO:0060631)2.33862740
148cartilage morphogenesis (GO:0060536)2.33857280
149non-recombinational repair (GO:0000726)2.33085083
150double-strand break repair via nonhomologous end joining (GO:0006303)2.33085083
151serine family amino acid biosynthetic process (GO:0009070)2.30809641
152maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.29538039
153white fat cell differentiation (GO:0050872)2.28392132
154pteridine-containing compound biosynthetic process (GO:0042559)2.26749178
155iron coordination entity transport (GO:1901678)2.25426472
156protein-cofactor linkage (GO:0018065)2.25425094
157meiotic chromosome segregation (GO:0045132)2.23492504
158alternative mRNA splicing, via spliceosome (GO:0000380)2.19790743
159DNA replication checkpoint (GO:0000076)2.18802419
160female gonad development (GO:0008585)2.16110639
161intra-S DNA damage checkpoint (GO:0031573)2.14643524
162cerebral cortex radially oriented cell migration (GO:0021799)2.13608320
163dendrite morphogenesis (GO:0048813)2.12729928
164hindbrain development (GO:0030902)2.12449147
165replication fork processing (GO:0031297)2.11354592
166activin receptor signaling pathway (GO:0032924)2.11345441
167positive regulation of heart growth (GO:0060421)2.11020500
168protein polyglutamylation (GO:0018095)2.10409722
169axonal fasciculation (GO:0007413)2.09707381
170regulation of gonadotropin secretion (GO:0032276)2.08864380
171regulation of timing of cell differentiation (GO:0048505)2.08330681
172paraxial mesoderm development (GO:0048339)2.06094215
173negative regulation of Ras GTPase activity (GO:0034261)2.05121288
174cellular response to BMP stimulus (GO:0071773)2.04868966
175response to BMP (GO:0071772)2.04868966
176IMP biosynthetic process (GO:0006188)2.04143881
177negative regulation of astrocyte differentiation (GO:0048712)2.03938915

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse5.08136333
2EZH2_22144423_ChIP-Seq_EOC_Human5.05496942
3GBX2_23144817_ChIP-Seq_PC3_Human3.77546746
4SALL1_21062744_ChIP-ChIP_HESCs_Human2.79674613
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.48817173
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.41702426
7IGF1R_20145208_ChIP-Seq_DFB_Human2.35435543
8SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.26514429
9GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.26390399
10ZFP57_27257070_Chip-Seq_ESCs_Mouse2.26191090
11JARID2_20064375_ChIP-Seq_MESCs_Mouse2.16315077
12REST_21632747_ChIP-Seq_MESCs_Mouse2.15754077
13SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.14369987
14E2F7_22180533_ChIP-Seq_HELA_Human2.11406349
15BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.08113048
16HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.08072798
17TAF15_26573619_Chip-Seq_HEK293_Human2.00415390
18DROSHA_22980978_ChIP-Seq_HELA_Human1.98271789
19CTBP2_25329375_ChIP-Seq_LNCAP_Human1.97603491
20CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.93858154
21EZH2_27304074_Chip-Seq_ESCs_Mouse1.93838175
22ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.92073603
23SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.90764879
24* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.87106500
25SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.85539517
26RNF2_18974828_ChIP-Seq_MESCs_Mouse1.84144622
27EZH2_18974828_ChIP-Seq_MESCs_Mouse1.84144622
28SMAD4_21799915_ChIP-Seq_A2780_Human1.83652651
29CTBP1_25329375_ChIP-Seq_LNCAP_Human1.83050306
30* EZH2_27294783_Chip-Seq_ESCs_Mouse1.81484824
31NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.80410158
32CBX2_27304074_Chip-Seq_ESCs_Mouse1.80203406
33MTF2_20144788_ChIP-Seq_MESCs_Mouse1.79684193
34SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.78622217
35SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.77284650
36EWS_26573619_Chip-Seq_HEK293_Human1.75755495
37POU3F2_20337985_ChIP-ChIP_501MEL_Human1.75424769
38JARID2_20075857_ChIP-Seq_MESCs_Mouse1.74392142
39RNF2_27304074_Chip-Seq_ESCs_Mouse1.72202797
40EED_16625203_ChIP-ChIP_MESCs_Mouse1.68733124
41SUZ12_27294783_Chip-Seq_ESCs_Mouse1.68455168
42PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.66137263
43RNF2_27304074_Chip-Seq_NSC_Mouse1.65796926
44AR_21572438_ChIP-Seq_LNCaP_Human1.65338026
45BMI1_23680149_ChIP-Seq_NPCS_Mouse1.62555807
46P300_19829295_ChIP-Seq_ESCs_Human1.61625185
47PIAS1_25552417_ChIP-Seq_VCAP_Human1.60410746
48FLI1_27457419_Chip-Seq_LIVER_Mouse1.58648842
49FUS_26573619_Chip-Seq_HEK293_Human1.58201263
50STAT3_23295773_ChIP-Seq_U87_Human1.57383465
51PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.55077634
52PCGF2_27294783_Chip-Seq_ESCs_Mouse1.49113560
53TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.48569998
54REST_18959480_ChIP-ChIP_MESCs_Mouse1.46653205
55NANOG_18555785_Chip-Seq_ESCs_Mouse1.43753735
56SMAD_19615063_ChIP-ChIP_OVARY_Human1.43715209
57CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.42517801
58AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.42418898
59TOP2B_26459242_ChIP-Seq_MCF-7_Human1.41041698
60TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.40725713
61POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.40725713
62CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.40613369
63* SMAD3_21741376_ChIP-Seq_EPCs_Human1.39655092
64ZNF274_21170338_ChIP-Seq_K562_Hela1.39479693
65MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.36014730
66MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.35679739
67TCF4_23295773_ChIP-Seq_U87_Human1.35325491
68AR_25329375_ChIP-Seq_VCAP_Human1.34956825
69* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34474823
70POU5F1_16153702_ChIP-ChIP_HESCs_Human1.34101468
71ER_23166858_ChIP-Seq_MCF-7_Human1.31293809
72BCAT_22108803_ChIP-Seq_LS180_Human1.31199776
73OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.29452185
74* RARB_27405468_Chip-Seq_BRAIN_Mouse1.28207595
75SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.27269127
76NR3C1_21868756_ChIP-Seq_MCF10A_Human1.26478287
77EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.25635312
78VDR_22108803_ChIP-Seq_LS180_Human1.25615203
79* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24612391
80IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.24205223
81CBP_20019798_ChIP-Seq_JUKART_Human1.24205223
82KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.23443876
83RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.23178908
84E2F1_18555785_Chip-Seq_ESCs_Mouse1.22421805
85SUZ12_27294783_Chip-Seq_NPCs_Mouse1.22014814
86IKZF1_21737484_ChIP-ChIP_HCT116_Human1.21584847
87CMYC_18555785_Chip-Seq_ESCs_Mouse1.19103702
88P53_22387025_ChIP-Seq_ESCs_Mouse1.18903685
89KLF5_20875108_ChIP-Seq_MESCs_Mouse1.18049876
90SOX2_21211035_ChIP-Seq_LN229_Gbm1.17002164
91STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.16835386
92* SMAD4_21741376_ChIP-Seq_HESCs_Human1.16449261
93MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.16405272
94TAL1_26923725_Chip-Seq_HPCs_Mouse1.16170432
95* RUNX2_22187159_ChIP-Seq_PCA_Human1.16142898
96TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.16081696
97GATA1_26923725_Chip-Seq_HPCs_Mouse1.15887758
98* SMAD3_21741376_ChIP-Seq_HESCs_Human1.14558063
99UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.13826603
100CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.11616330
101SMAD3_21741376_ChIP-Seq_ESCs_Human1.10410072
102ARNT_22903824_ChIP-Seq_MCF-7_Human1.10004183
103TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.09685197
104SUZ12_18555785_Chip-Seq_ESCs_Mouse1.09600362
105* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09377093
106KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.09171700
107AR_19668381_ChIP-Seq_PC3_Human1.09042453
108* TCF4_22108803_ChIP-Seq_LS180_Human1.08822979
109CDX2_19796622_ChIP-Seq_MESCs_Mouse1.08711210
110* SMAD4_21741376_ChIP-Seq_EPCs_Human1.08336549
111PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.07499027
112YAP1_20516196_ChIP-Seq_MESCs_Mouse1.07204895
113NR3C1_23031785_ChIP-Seq_PC12_Mouse1.06645963
114* EZH2_27294783_Chip-Seq_NPCs_Mouse1.06423384
115NFE2_27457419_Chip-Seq_LIVER_Mouse1.06171811
116JUN_21703547_ChIP-Seq_K562_Human1.06104230
117STAT3_18555785_Chip-Seq_ESCs_Mouse1.05541960
118PCGF2_27294783_Chip-Seq_NPCs_Mouse1.04833282
119P300_18555785_Chip-Seq_ESCs_Mouse1.04798196
120FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.03236615
121KDM2B_26808549_Chip-Seq_REH_Human1.02920442
122CDX2_22108803_ChIP-Seq_LS180_Human0.99829911
123MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.97134645
124TBL1_22424771_ChIP-Seq_293T_Human0.96534279
125* TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.96198546
126SOX9_26525672_Chip-Seq_HEART_Mouse0.94976204
127CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.93942179
128TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.93631852

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.06051051
2MP0003880_abnormal_central_pattern3.99540642
3MP0003890_abnormal_embryonic-extraembry3.22485816
4MP0009046_muscle_twitch3.13853549
5MP0003635_abnormal_synaptic_transmissio3.13786076
6MP0005423_abnormal_somatic_nervous2.92933843
7MP0004270_analgesia2.86949842
8MP0009745_abnormal_behavioral_response2.76179941
9MP0001486_abnormal_startle_reflex2.62419214
10MP0005410_abnormal_fertilization2.60957156
11MP0001188_hyperpigmentation2.57554748
12MP0005646_abnormal_pituitary_gland2.52792251
13MP0002063_abnormal_learning/memory/cond2.50003885
14MP0002064_seizures2.49767049
15MP0002572_abnormal_emotion/affect_behav2.45150625
16MP0001984_abnormal_olfaction2.31891531
17MP0002734_abnormal_mechanical_nocicepti2.31195231
18MP0001905_abnormal_dopamine_level2.29787979
19MP0002272_abnormal_nervous_system2.24284164
20MP0001968_abnormal_touch/_nociception2.18446312
21MP0001501_abnormal_sleep_pattern2.16869388
22MP0008995_early_reproductive_senescence2.12193106
23MP0002938_white_spotting2.08370901
24MP0001529_abnormal_vocalization2.07333651
25MP0002822_catalepsy2.06997634
26MP0005551_abnormal_eye_electrophysiolog1.97369866
27MP0006276_abnormal_autonomic_nervous1.94361609
28MP0002557_abnormal_social/conspecific_i1.89911505
29MP0002067_abnormal_sensory_capabilities1.89520757
30MP0003787_abnormal_imprinting1.81673570
31MP0006292_abnormal_olfactory_placode1.78503355
32MP0004147_increased_porphyrin_level1.78468305
33MP0000778_abnormal_nervous_system1.76970693
34MP0002736_abnormal_nociception_after1.73159454
35MP0001502_abnormal_circadian_rhythm1.70760238
36MP0005645_abnormal_hypothalamus_physiol1.68272041
37MP0003937_abnormal_limbs/digits/tail_de1.63491020
38MP0004924_abnormal_behavior1.61616503
39MP0005386_behavior/neurological_phenoty1.61616503
40MP0002184_abnormal_innervation1.60915320
41MP0002735_abnormal_chemical_nociception1.59414727
42MP0003119_abnormal_digestive_system1.59244901
43MP0001440_abnormal_grooming_behavior1.56676461
44MP0002733_abnormal_thermal_nociception1.54701571
45MP0003136_yellow_coat_color1.54034204
46MP0005367_renal/urinary_system_phenotyp1.49757311
47MP0000516_abnormal_urinary_system1.49757311
48MP0006072_abnormal_retinal_apoptosis1.47227260
49MP0003698_abnormal_male_reproductive1.47223690
50MP0008569_lethality_at_weaning1.46873553
51MP0005409_darkened_coat_color1.45830031
52MP0002909_abnormal_adrenal_gland1.44330738
53MP0001970_abnormal_pain_threshold1.43882526
54MP0004885_abnormal_endolymph1.43404906
55MP0003195_calcinosis1.41045532
56MP0000569_abnormal_digit_pigmentation1.38946902
57MP0002882_abnormal_neuron_morphology1.38079789
58MP0009780_abnormal_chondrocyte_physiolo1.37564133
59MP0002233_abnormal_nose_morphology1.36758469
60MP0000631_abnormal_neuroendocrine_gland1.35546361
61MP0003122_maternal_imprinting1.34999229
62MP0000955_abnormal_spinal_cord1.34718583
63MP0004142_abnormal_muscle_tone1.32638139
64MP0002653_abnormal_ependyma_morphology1.29937330
65MP0004811_abnormal_neuron_physiology1.25940455
66MP0002066_abnormal_motor_capabilities/c1.21583717
67MP0005253_abnormal_eye_physiology1.21275356
68MP0010386_abnormal_urinary_bladder1.21100913
69MP0008877_abnormal_DNA_methylation1.19771517
70MP0010094_abnormal_chromosome_stability1.18501201
71MP0004742_abnormal_vestibular_system1.17931224
72MP0003123_paternal_imprinting1.16287154
73MP0003942_abnormal_urinary_system1.13943940
74MP0002638_abnormal_pupillary_reflex1.13079741
75MP0002229_neurodegeneration1.12261048
76MP0002837_dystrophic_cardiac_calcinosis1.10881166
77MP0005187_abnormal_penis_morphology1.10380264
78MP0002152_abnormal_brain_morphology1.10007540
79MP0005499_abnormal_olfactory_system1.08839200
80MP0005394_taste/olfaction_phenotype1.08839200
81MP0003567_abnormal_fetal_cardiomyocyte1.08701477
82MP0000566_synostosis1.06719552
83MP0002752_abnormal_somatic_nervous1.06377489
84MP0001293_anophthalmia1.05630841
85MP0008058_abnormal_DNA_repair1.05037309
86MP0003385_abnormal_body_wall1.03186957
87MP0003633_abnormal_nervous_system1.01556156
88MP0001661_extended_life_span0.99306114
89MP0001929_abnormal_gametogenesis0.98562903
90MP0001963_abnormal_hearing_physiology0.97141321
91MP0001286_abnormal_eye_development0.96306817
92MP0004133_heterotaxia0.93269136
93MP0003631_nervous_system_phenotype0.92044855
94MP0004145_abnormal_muscle_electrophysio0.91702216
95MP0002102_abnormal_ear_morphology0.91066304
96MP0003283_abnormal_digestive_organ0.90245451
97MP0002084_abnormal_developmental_patter0.89953098
98MP0005360_urolithiasis0.89662873
99MP0001177_atelectasis0.89302491
100MP0000534_abnormal_ureter_morphology0.88939123
101MP0003879_abnormal_hair_cell0.88443033
102MP0009697_abnormal_copulation0.88068507
103MP0008057_abnormal_DNA_replication0.85840726
104MP0003634_abnormal_glial_cell0.85229048
105MP0000647_abnormal_sebaceous_gland0.83809967
106MP0008872_abnormal_physiological_respon0.83639488
107MP0003938_abnormal_ear_development0.83386093
108MP0002160_abnormal_reproductive_system0.82237744
109MP0000026_abnormal_inner_ear0.82224500
110MP0003935_abnormal_craniofacial_develop0.82032976
111MP0001299_abnormal_eye_distance/0.81978128
112MP0010030_abnormal_orbit_morphology0.81225417
113MP0000049_abnormal_middle_ear0.79970585
114MP0002069_abnormal_eating/drinking_beha0.77861154
115MP0002161_abnormal_fertility/fecundity0.77551632
116MP0003632_abnormal_nervous_system0.76803313
117MP0005670_abnormal_white_adipose0.76141096
118MP0001986_abnormal_taste_sensitivity0.75319135
119MP0005379_endocrine/exocrine_gland_phen0.73462972
120MP0001485_abnormal_pinna_reflex0.73236566
121MP0002210_abnormal_sex_determination0.73219917
122MP0004085_abnormal_heartbeat0.73096290
123MP0005195_abnormal_posterior_eye0.72787573
124MP0003121_genomic_imprinting0.72634536
125MP0008004_abnormal_stomach_pH0.72002329
126MP0005248_abnormal_Harderian_gland0.71775756
127MP0005171_absent_coat_pigmentation0.71339300
128MP0008789_abnormal_olfactory_epithelium0.71125013
129MP0003690_abnormal_glial_cell0.70125065
130MP0002090_abnormal_vision0.69928091
131MP0003861_abnormal_nervous_system0.69469799
132MP0004043_abnormal_pH_regulation0.66183076
133MP0004858_abnormal_nervous_system0.65945556
134MP0005535_abnormal_body_temperature0.65595997

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)6.86193409
2Abnormal respiratory motile cilium physiology (HP:0012261)6.17344904
3Absent/shortened dynein arms (HP:0200106)5.82856109
4Dynein arm defect of respiratory motile cilia (HP:0012255)5.82856109
5Abnormal ciliary motility (HP:0012262)5.78246752
6Abnormal respiratory epithelium morphology (HP:0012253)5.05894117
7Abnormal respiratory motile cilium morphology (HP:0005938)5.05894117
8Rhinitis (HP:0012384)4.62362449
9Abnormality of pyruvate family amino acid metabolism (HP:0010915)4.08285631
10Abnormality of alanine metabolism (HP:0010916)4.08285631
11Hyperalaninemia (HP:0003348)4.08285631
12Focal motor seizures (HP:0011153)4.06103119
13Medial flaring of the eyebrow (HP:0010747)3.96055400
14Gait imbalance (HP:0002141)3.94514915
15True hermaphroditism (HP:0010459)3.90395517
16Pancreatic fibrosis (HP:0100732)3.83721594
17Congenital primary aphakia (HP:0007707)3.75179556
18Nephrogenic diabetes insipidus (HP:0009806)3.54791813
19Limb dystonia (HP:0002451)3.45679057
20Epileptic encephalopathy (HP:0200134)3.44177024
21Progressive cerebellar ataxia (HP:0002073)3.36294388
22Genital tract atresia (HP:0001827)3.33312593
23Occipital encephalocele (HP:0002085)3.30596122
24Vaginal atresia (HP:0000148)3.27623279
25Febrile seizures (HP:0002373)3.17434183
26Intestinal atresia (HP:0011100)3.13242048
27Chronic bronchitis (HP:0004469)3.10030905
28Male infertility (HP:0003251)3.09866732
29Infertility (HP:0000789)3.03538646
30Gaze-evoked nystagmus (HP:0000640)2.95530921
31Poor coordination (HP:0002370)2.94285167
32Pancreatic cysts (HP:0001737)2.88834961
33Focal seizures (HP:0007359)2.85288585
34Genetic anticipation (HP:0003743)2.81401173
35Nephronophthisis (HP:0000090)2.80296261
36Molar tooth sign on MRI (HP:0002419)2.78443486
37Abnormality of midbrain morphology (HP:0002418)2.78443486
38Abnormality of the labia minora (HP:0012880)2.77567572
39Cystic liver disease (HP:0006706)2.68135817
40Tubulointerstitial nephritis (HP:0001970)2.65981330
41Myokymia (HP:0002411)2.63478734
42Abnormal umbilical cord blood vessels (HP:0011403)2.60905432
43Single umbilical artery (HP:0001195)2.60905432
44Abnormality of the fetal cardiovascular system (HP:0010948)2.60905432
45Chromosomal breakage induced by crosslinking agents (HP:0003221)2.58917980
46Chromsome breakage (HP:0040012)2.58224426
47Constricted visual fields (HP:0001133)2.52550413
48Aplasia/Hypoplasia of the tongue (HP:0010295)2.47691276
49Hepatoblastoma (HP:0002884)2.43746501
50Birth length less than 3rd percentile (HP:0003561)2.41402872
51Atonic seizures (HP:0010819)2.41044465
52Septo-optic dysplasia (HP:0100842)2.40893782
53Volvulus (HP:0002580)2.37020739
54Abnormal lung lobation (HP:0002101)2.36336562
55Aplasia/Hypoplasia of the lens (HP:0008063)2.35331362
56Visual hallucinations (HP:0002367)2.33011419
57Postaxial foot polydactyly (HP:0001830)2.32859056
58Degeneration of the lateral corticospinal tracts (HP:0002314)2.32077067
59Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.32077067
60Abnormality of macular pigmentation (HP:0008002)2.32010880
61Bronchiectasis (HP:0002110)2.29916766
62Abnormality of the corticospinal tract (HP:0002492)2.28688347
63Broad-based gait (HP:0002136)2.25310916
64Abnormality of the renal medulla (HP:0100957)2.24372514
65Supernumerary spleens (HP:0009799)2.21635598
66Chronic hepatic failure (HP:0100626)2.21149503
67Specific learning disability (HP:0001328)2.17880001
68Osteomalacia (HP:0002749)2.16905638
69Colon cancer (HP:0003003)2.14243842
70Proximal tubulopathy (HP:0000114)2.13557136
71Agitation (HP:0000713)2.13195660
72Oligodactyly (hands) (HP:0001180)2.12248851
73Action tremor (HP:0002345)2.11031663
74Bifid tongue (HP:0010297)2.10498102
75Maternal diabetes (HP:0009800)2.09808593
76Male pseudohermaphroditism (HP:0000037)2.09332069
77Urinary bladder sphincter dysfunction (HP:0002839)2.08232222
78Hyperventilation (HP:0002883)2.07339286
79Postaxial hand polydactyly (HP:0001162)2.07328113
80Hemiparesis (HP:0001269)2.05571615
81Congenital sensorineural hearing impairment (HP:0008527)2.03381848
82Generalized tonic-clonic seizures (HP:0002069)2.02778885
83Abnormal pancreas size (HP:0012094)2.02658999
84Cortical dysplasia (HP:0002539)1.99787040
85Cutaneous finger syndactyly (HP:0010554)1.99470726
86Bile duct proliferation (HP:0001408)1.98569967
87Abnormal biliary tract physiology (HP:0012439)1.98569967
88Abnormality of cochlea (HP:0000375)1.97998552
89Central scotoma (HP:0000603)1.97218192
90Epidermoid cyst (HP:0200040)1.96773669
91Congenital stationary night blindness (HP:0007642)1.96130130
92Hemiplegia (HP:0002301)1.95400234
93Truncal ataxia (HP:0002078)1.93747188
94Abnormal connection of the cardiac segments (HP:0011545)1.93705446
95Abnormal ventriculo-arterial connection (HP:0011563)1.93705446
96Transposition of the great arteries (HP:0001669)1.93705446
97Congenital hepatic fibrosis (HP:0002612)1.93104487
98Abnormality of serum amino acid levels (HP:0003112)1.90708683
99Absence seizures (HP:0002121)1.90595572
100Homocystinuria (HP:0002156)1.89994889
101Abnormality of homocysteine metabolism (HP:0010919)1.89994889
102Hyperglycinemia (HP:0002154)1.89688495
103Aplasia/Hypoplasia of the uvula (HP:0010293)1.88097690
104Double outlet right ventricle (HP:0001719)1.87889845
105Congenital malformation of the right heart (HP:0011723)1.87889845
106Fetal akinesia sequence (HP:0001989)1.87783828
107Impaired vibration sensation in the lower limbs (HP:0002166)1.87456927
108Median cleft lip (HP:0000161)1.86826383
109Decreased central vision (HP:0007663)1.85921088
110Absent radius (HP:0003974)1.85082229
111Aplasia/Hypoplasia of the tibia (HP:0005772)1.84987169
112Anophthalmia (HP:0000528)1.84426863
113Gastrointestinal atresia (HP:0002589)1.83942207
114Esophageal varix (HP:0002040)1.82102575
115Aplasia involving bones of the upper limbs (HP:0009823)1.82061679
116Aplasia of the phalanges of the hand (HP:0009802)1.82061679
117Aplasia involving bones of the extremities (HP:0009825)1.82061679
118Absent speech (HP:0001344)1.81659481
119Retinal dysplasia (HP:0007973)1.81049306
120Pheochromocytoma (HP:0002666)1.80575128
121Abnormality of the astrocytes (HP:0100707)1.79983507
122Astrocytoma (HP:0009592)1.79983507
123Abnormal hair whorl (HP:0010721)1.79810438
124Insidious onset (HP:0003587)1.79421821
125Termporal pattern (HP:0011008)1.79421821
126Myelomeningocele (HP:0002475)1.79289436
127Preaxial hand polydactyly (HP:0001177)1.79124874
128Hypomagnesemia (HP:0002917)1.78383902
129Widely spaced teeth (HP:0000687)1.77961301
130Anencephaly (HP:0002323)1.77220997
131Horseshoe kidney (HP:0000085)1.75689120
132Small hand (HP:0200055)1.75662290
133Hypoplastic left heart (HP:0004383)1.74496930
134Abnormality of permanent molar morphology (HP:0011071)1.74178434
135Abnormality of the dental root (HP:0006486)1.74178434
136Taurodontia (HP:0000679)1.74178434
137Dialeptic seizures (HP:0011146)1.73478413
138Cutaneous syndactyly (HP:0012725)1.73169736
139Dysdiadochokinesis (HP:0002075)1.73015430
140Absent forearm bone (HP:0003953)1.72931405
141Aplasia involving forearm bones (HP:0009822)1.72931405
142Epileptiform EEG discharges (HP:0011182)1.71090659
143Abnormality of molar morphology (HP:0011070)1.70003141
144Abnormality of molar (HP:0011077)1.70003141
145Sclerocornea (HP:0000647)1.69711669
146Broad foot (HP:0001769)1.69522636
147Renal hypoplasia (HP:0000089)1.69389116
148Stenosis of the external auditory canal (HP:0000402)1.69147818
149Absent septum pellucidum (HP:0001331)1.69122333
150Labial hypoplasia (HP:0000066)1.68135612
151EEG with generalized epileptiform discharges (HP:0011198)1.68010732
152Neoplasm of the oral cavity (HP:0100649)1.67818579
153Abnormality of chromosome stability (HP:0003220)1.66316168
154Papillary thyroid carcinoma (HP:0002895)1.64825492
155Abnormality of the dental pulp (HP:0006479)1.64587985
156Abnormality of sulfur amino acid metabolism (HP:0004339)1.63364582
157Meckel diverticulum (HP:0002245)1.63022673
158White forelock (HP:0002211)1.62885705
159Ectopic kidney (HP:0000086)1.61181792
160Blue irides (HP:0000635)1.60876188
161Oculomotor apraxia (HP:0000657)1.60798158
162Abnormality of ocular smooth pursuit (HP:0000617)1.60463306
163Optic nerve hypoplasia (HP:0000609)1.60064850

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK33.56258840
2MAP2K72.92931404
3ACVR1B2.90644361
4MAP3K42.78548752
5MARK12.76842807
6TNIK2.74799569
7CASK2.71314107
8PNCK2.70854310
9PRKD32.60199762
10NTRK22.56204302
11EPHA42.45131448
12BRSK22.44765019
13MAPK132.17055791
14FRK2.10202154
15INSRR1.98635102
16MUSK1.93454018
17MAP3K91.86362755
18PRPF4B1.76916090
19BMPR21.74829820
20BRD41.73771261
21MAPKAPK51.71515696
22MINK11.56455439
23PLK41.51881307
24SGK21.48292183
25STK381.41444872
26SGK2231.39639280
27SGK4941.39639280
28MAP2K41.38046189
29WEE11.36113018
30PINK11.35874579
31STK38L1.34789070
32BRSK11.34272246
33STK391.33607302
34PAK61.32119687
35CSNK1G21.26165886
36WNK41.25495663
37CDC71.25163045
38CAMK1G1.20166890
39PLK21.18246854
40WNK11.17247534
41PRKCG1.16319141
42ERBB41.15877124
43CDK31.14986482
44ERBB31.14705980
45CAMK2A1.13923864
46TRIM281.12502313
47TTK1.11259843
48ZAK1.10308000
49DYRK21.09914209
50NEK61.08050497
51STK31.05910967
52CDK51.05415332
53AKT31.04930761
54MKNK11.04377690
55GRK11.03459857
56OXSR11.01158465
57TNK21.01076521
58PDK20.99757176
59MAP3K120.98827908
60KSR10.98084414
61CDC42BPA0.95001490
62CSNK1G30.94581368
63CAMK2B0.94443122
64GRK50.93147289
65CAMKK20.92574681
66NTRK10.91804037
67SGK30.91465293
68PLK30.89459769
69FGR0.89038007
70PDK30.87604295
71PDK40.87604295
72PHKG20.86491781
73PHKG10.86491781
74PAK30.85750518
75PBK0.82243036
76CAMKK10.81488222
77PLK10.81399033
78PTK2B0.80695531
79PRKCE0.80362159
80LATS20.79856880
81WNK30.79663794
82NEK20.78714631
83CSNK1A1L0.75649561
84CAMK2D0.75421546
85EIF2AK30.73958313
86CCNB10.73845530
87ICK0.73683040
88BCR0.73043766
89NLK0.73026723
90CSNK1G10.73009534
91UHMK10.72211251
92DYRK1A0.72053333
93ATR0.71857628
94ARAF0.71856108
95MAP3K60.70701961
96ADRBK20.70264586
97IRAK20.69410343
98TYRO30.68915992
99SGK10.66949975
100RIPK40.66019390
101MAPK150.64441344
102CSNK1A10.61979030
103CAMK2G0.61783160
104SIK20.61768640
105DAPK20.60992505
106FES0.60753469
107FGFR10.59896772
108LATS10.59782256
109ATM0.59438973
110FGFR20.58931288
111STK110.58096041
112CAMK10.57850970
113MKNK20.56629697
114NUAK10.55896234
115CDK180.54423116
116CSNK1E0.54247106
117CHEK20.53170627
118CDK150.51569921
119TAF10.51044006
120HIPK20.49779509
121PRKCH0.49634170
122RPS6KA20.48121237
123SRPK10.47882905
124ERBB20.47651421
125PKN10.46851909
126PRKD20.45711930
127BMPR1B0.45571462
128TIE10.45248510
129CDK90.45143784
130PRKG10.45029717
131CSNK1D0.44957397
132BRAF0.44602777
133CDK190.44319995
134CDK11A0.41987372
135RPS6KA30.41847086
136SIK30.41572621
137NME10.41567814
138MAPK100.41464137
139EPHB20.41205443
140RPS6KB10.41143826
141MARK20.40666905
142PRKACA0.40551986
143CDK20.39825623
144PRKDC0.39750935

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.86333414
2Synaptic vesicle cycle_Homo sapiens_hsa047213.15890787
3GABAergic synapse_Homo sapiens_hsa047272.73243094
4Circadian entrainment_Homo sapiens_hsa047132.68274817
5Amphetamine addiction_Homo sapiens_hsa050312.65991873
6Olfactory transduction_Homo sapiens_hsa047402.65646991
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.60847251
8Glutamatergic synapse_Homo sapiens_hsa047242.60431198
9Morphine addiction_Homo sapiens_hsa050322.58242224
10Cocaine addiction_Homo sapiens_hsa050302.54620619
11Insulin secretion_Homo sapiens_hsa049112.33455453
12Dopaminergic synapse_Homo sapiens_hsa047282.17786251
13Serotonergic synapse_Homo sapiens_hsa047262.16121476
14Long-term potentiation_Homo sapiens_hsa047202.13122444
15One carbon pool by folate_Homo sapiens_hsa006702.10509536
16Taste transduction_Homo sapiens_hsa047422.08477275
17Phototransduction_Homo sapiens_hsa047441.96650883
18Cholinergic synapse_Homo sapiens_hsa047251.89896019
19Salivary secretion_Homo sapiens_hsa049701.89601580
20Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.80743406
21Non-homologous end-joining_Homo sapiens_hsa034501.74481779
22Long-term depression_Homo sapiens_hsa047301.70846574
23Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.64304049
24Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.63321111
25Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.63188792
26Butanoate metabolism_Homo sapiens_hsa006501.62874849
27Arginine biosynthesis_Homo sapiens_hsa002201.62721352
28Steroid biosynthesis_Homo sapiens_hsa001001.61872139
29Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.60331110
30Calcium signaling pathway_Homo sapiens_hsa040201.59669885
31Collecting duct acid secretion_Homo sapiens_hsa049661.58327971
32Renin secretion_Homo sapiens_hsa049241.57044926
33Aldosterone synthesis and secretion_Homo sapiens_hsa049251.56292209
34Cysteine and methionine metabolism_Homo sapiens_hsa002701.53958114
35Gastric acid secretion_Homo sapiens_hsa049711.49037772
36Propanoate metabolism_Homo sapiens_hsa006401.44221656
37Basal transcription factors_Homo sapiens_hsa030221.42639920
38GnRH signaling pathway_Homo sapiens_hsa049121.36815666
39Ovarian steroidogenesis_Homo sapiens_hsa049131.29870405
402-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.27803137
41Circadian rhythm_Homo sapiens_hsa047101.27248881
42Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.27018226
43cAMP signaling pathway_Homo sapiens_hsa040241.26738737
44Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.22778588
45Selenocompound metabolism_Homo sapiens_hsa004501.22624785
46Mismatch repair_Homo sapiens_hsa034301.21793316
47mRNA surveillance pathway_Homo sapiens_hsa030151.20878103
48Oxytocin signaling pathway_Homo sapiens_hsa049211.20502413
49Sulfur relay system_Homo sapiens_hsa041221.18866631
50Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.16947612
51Dorso-ventral axis formation_Homo sapiens_hsa043201.16550284
52Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.12845940
53Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.12700783
54Gap junction_Homo sapiens_hsa045401.11673457
55Phosphatidylinositol signaling system_Homo sapiens_hsa040701.09732537
56Vibrio cholerae infection_Homo sapiens_hsa051101.05819172
57Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.05412330
58Type II diabetes mellitus_Homo sapiens_hsa049301.04435393
59Homologous recombination_Homo sapiens_hsa034401.04173314
60Retinol metabolism_Homo sapiens_hsa008301.02914389
61RNA transport_Homo sapiens_hsa030131.01408405
62RNA degradation_Homo sapiens_hsa030181.00981237
63Estrogen signaling pathway_Homo sapiens_hsa049150.95652300
64Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.95263341
65Melanogenesis_Homo sapiens_hsa049160.94708300
66cGMP-PKG signaling pathway_Homo sapiens_hsa040220.93101965
67Basal cell carcinoma_Homo sapiens_hsa052170.92433295
68Axon guidance_Homo sapiens_hsa043600.91629968
69Hippo signaling pathway_Homo sapiens_hsa043900.91042686
70Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.90464595
71Nitrogen metabolism_Homo sapiens_hsa009100.90269921
72Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.88509687
73Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.87222291
74Pancreatic secretion_Homo sapiens_hsa049720.87187888
75Cardiac muscle contraction_Homo sapiens_hsa042600.86828250
76Vascular smooth muscle contraction_Homo sapiens_hsa042700.85205987
77Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.84488571
78ErbB signaling pathway_Homo sapiens_hsa040120.84391001
79beta-Alanine metabolism_Homo sapiens_hsa004100.84279025
80Folate biosynthesis_Homo sapiens_hsa007900.83813821
81Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.82205338
82Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.79366027
83Cell cycle_Homo sapiens_hsa041100.76838445
84Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.75442634
85Alcoholism_Homo sapiens_hsa050340.74858157
86Oocyte meiosis_Homo sapiens_hsa041140.74343548
87Thyroid hormone synthesis_Homo sapiens_hsa049180.74081451
88SNARE interactions in vesicular transport_Homo sapiens_hsa041300.73563928
89Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.71697448
90Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71133889
91Ether lipid metabolism_Homo sapiens_hsa005650.70122880
92Peroxisome_Homo sapiens_hsa041460.67970665
93Phospholipase D signaling pathway_Homo sapiens_hsa040720.67716033
94Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.67655736
95Pyruvate metabolism_Homo sapiens_hsa006200.67173163
96Arginine and proline metabolism_Homo sapiens_hsa003300.65717111
97MAPK signaling pathway_Homo sapiens_hsa040100.65057535
98Fatty acid metabolism_Homo sapiens_hsa012120.64404637
99Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.64278968
100Carbohydrate digestion and absorption_Homo sapiens_hsa049730.63304145
101Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.62904687
102Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.62470842
103Glycerophospholipid metabolism_Homo sapiens_hsa005640.62444983
104Choline metabolism in cancer_Homo sapiens_hsa052310.62409718
105Wnt signaling pathway_Homo sapiens_hsa043100.62149907
106Chemical carcinogenesis_Homo sapiens_hsa052040.61623808
107Inositol phosphate metabolism_Homo sapiens_hsa005620.60647548
108Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.60123844
109Hedgehog signaling pathway_Homo sapiens_hsa043400.59291103
110Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.58598667
111Glucagon signaling pathway_Homo sapiens_hsa049220.57993449
112Type I diabetes mellitus_Homo sapiens_hsa049400.57656540
113Ras signaling pathway_Homo sapiens_hsa040140.57079767
114Vitamin digestion and absorption_Homo sapiens_hsa049770.56758272
115Fatty acid biosynthesis_Homo sapiens_hsa000610.56382359
116Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.54408271
117Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.54235646
118Lysine degradation_Homo sapiens_hsa003100.53754243
119TGF-beta signaling pathway_Homo sapiens_hsa043500.52907886
120Protein export_Homo sapiens_hsa030600.52652770
121Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.51103480
122Tight junction_Homo sapiens_hsa045300.50914417
123Dilated cardiomyopathy_Homo sapiens_hsa054140.50713805
124Huntingtons disease_Homo sapiens_hsa050160.50552360
125Fatty acid degradation_Homo sapiens_hsa000710.48884154
126Glioma_Homo sapiens_hsa052140.46581536
127Tryptophan metabolism_Homo sapiens_hsa003800.46437292
128Adherens junction_Homo sapiens_hsa045200.46192169
129Spliceosome_Homo sapiens_hsa030400.45537319
130Steroid hormone biosynthesis_Homo sapiens_hsa001400.43902056
131Histidine metabolism_Homo sapiens_hsa003400.43519046
132Mineral absorption_Homo sapiens_hsa049780.43080623
133Rheumatoid arthritis_Homo sapiens_hsa053230.42891549
134Sphingolipid metabolism_Homo sapiens_hsa006000.41161452
135Thyroid hormone signaling pathway_Homo sapiens_hsa049190.41095858
136Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.40518080
137Vitamin B6 metabolism_Homo sapiens_hsa007500.39768237
138Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.39697144
139Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.39592424
140Prolactin signaling pathway_Homo sapiens_hsa049170.39413014
141Maturity onset diabetes of the young_Homo sapiens_hsa049500.37183755
142Rap1 signaling pathway_Homo sapiens_hsa040150.34758525
143Sulfur metabolism_Homo sapiens_hsa009200.32092151
144Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.31262956
145Alzheimers disease_Homo sapiens_hsa050100.31232820
146Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.30567301
147alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.29317035
148Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.28233743
149Fanconi anemia pathway_Homo sapiens_hsa034600.25676442
150Regulation of autophagy_Homo sapiens_hsa041400.23395494
151Linoleic acid metabolism_Homo sapiens_hsa005910.23163211

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