FAM162A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.28512941
2mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.65201857
3energy coupled proton transport, down electrochemical gradient (GO:0015985)5.50538690
4ATP synthesis coupled proton transport (GO:0015986)5.50538690
5viral transcription (GO:0019083)5.42406256
6oxidative phosphorylation (GO:0006119)5.32681457
7translational termination (GO:0006415)5.28963815
8establishment of protein localization to mitochondrial membrane (GO:0090151)5.00995051
9translational elongation (GO:0006414)4.84248675
10ribosomal small subunit biogenesis (GO:0042274)4.81739276
11DNA deamination (GO:0045006)4.76831525
12chaperone-mediated protein transport (GO:0072321)4.62817164
13SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.61772197
14protein targeting to ER (GO:0045047)4.50134070
15cotranslational protein targeting to membrane (GO:0006613)4.45757710
16respiratory electron transport chain (GO:0022904)4.38018282
17electron transport chain (GO:0022900)4.26388152
18establishment of protein localization to endoplasmic reticulum (GO:0072599)4.26325719
19protein localization to endoplasmic reticulum (GO:0070972)4.22401003
20viral life cycle (GO:0019058)4.12143791
21peptidyl-histidine modification (GO:0018202)4.08819462
22cellular protein complex disassembly (GO:0043624)4.07378390
23translational initiation (GO:0006413)4.07296917
24ribosomal large subunit biogenesis (GO:0042273)3.98876328
25nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.94990982
26mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.90455537
27maturation of SSU-rRNA (GO:0030490)3.87022928
28protein complex disassembly (GO:0043241)3.50792077
29translation (GO:0006412)3.50664603
30water-soluble vitamin biosynthetic process (GO:0042364)3.50007870
31protein neddylation (GO:0045116)3.47262280
32galactose catabolic process (GO:0019388)3.45426437
33tricarboxylic acid cycle (GO:0006099)3.44226609
34hydrogen ion transmembrane transport (GO:1902600)3.43867421
35aldehyde catabolic process (GO:0046185)3.41230929
36macromolecular complex disassembly (GO:0032984)3.32213405
37DNA strand elongation involved in DNA replication (GO:0006271)3.30241709
38formation of translation preinitiation complex (GO:0001731)3.29564078
39ATP biosynthetic process (GO:0006754)3.24803186
40telomere maintenance via semi-conservative replication (GO:0032201)3.22073606
41ribonucleoprotein complex biogenesis (GO:0022613)3.20194732
42positive regulation of mitochondrial fission (GO:0090141)3.19156647
43protein targeting to mitochondrion (GO:0006626)3.13672995
44DNA strand elongation (GO:0022616)3.12337191
45transcription elongation from RNA polymerase III promoter (GO:0006385)3.09453595
46termination of RNA polymerase III transcription (GO:0006386)3.09453595
47nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.06536118
48spliceosomal snRNP assembly (GO:0000387)3.05631363
49proton transport (GO:0015992)3.05490643
50intracellular protein transmembrane import (GO:0044743)3.04072523
51protein localization to mitochondrion (GO:0070585)3.02010591
52sarcomere organization (GO:0045214)3.01113903
53hydrogen transport (GO:0006818)2.99328695
54respiratory chain complex IV assembly (GO:0008535)2.98323469
55establishment of protein localization to mitochondrion (GO:0072655)2.97808575
56folic acid-containing compound biosynthetic process (GO:0009396)2.97426895
57exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.97145428
58nucleobase-containing small molecule interconversion (GO:0015949)2.96554917
59purine ribonucleoside monophosphate biosynthetic process (GO:0009168)2.96479350
60purine nucleoside monophosphate biosynthetic process (GO:0009127)2.96479350
61rRNA modification (GO:0000154)2.93028061
62purine nucleoside triphosphate biosynthetic process (GO:0009145)2.92935202
63protein targeting to membrane (GO:0006612)2.92054735
64regulation of mitochondrial translation (GO:0070129)2.90809795
65purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.89381530
66activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO2.88153473
67muscle filament sliding (GO:0030049)2.87519178
68actin-myosin filament sliding (GO:0033275)2.87519178
69pteridine-containing compound biosynthetic process (GO:0042559)2.84429882
70nuclear-transcribed mRNA catabolic process (GO:0000956)2.82395586
71cytochrome complex assembly (GO:0017004)2.82242165
72cellular component biogenesis (GO:0044085)2.80339194
73telomere maintenance via recombination (GO:0000722)2.79047823
74histone-serine phosphorylation (GO:0035404)2.78371001
75heart process (GO:0003015)2.78078986
76heart contraction (GO:0060047)2.78078986
77mitochondrial transport (GO:0006839)2.77965272
78ribonucleoside triphosphate biosynthetic process (GO:0009201)2.77088191
79deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.76725656
80aerobic respiration (GO:0009060)2.76109772
81AMP metabolic process (GO:0046033)2.76065879
82regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.75708386
83DNA damage response, detection of DNA damage (GO:0042769)2.73086041
84regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.72423862
85protein targeting (GO:0006605)2.72088682
86IMP biosynthetic process (GO:0006188)2.71653758
87positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.70926474
88tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.70857450
89RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.70857450
90negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.70708621
91nucleobase biosynthetic process (GO:0046112)2.68674563
92kinetochore organization (GO:0051383)2.66623930
93mRNA catabolic process (GO:0006402)2.66335709
944-hydroxyproline metabolic process (GO:0019471)2.65539596
95inner mitochondrial membrane organization (GO:0007007)2.64508873
96regulation of cofactor metabolic process (GO:0051193)2.63657989
97regulation of coenzyme metabolic process (GO:0051196)2.63657989
98establishment of protein localization to membrane (GO:0090150)2.63458378
99DNA replication initiation (GO:0006270)2.62945692
100negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.62661216
101negative regulation of ligase activity (GO:0051352)2.62661216
102nucleoside monophosphate biosynthetic process (GO:0009124)2.61282588
103ribonucleoside monophosphate biosynthetic process (GO:0009156)2.61207561
104mitochondrial respiratory chain complex I assembly (GO:0032981)2.60512541
105NADH dehydrogenase complex assembly (GO:0010257)2.60512541
106mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.60512541
107anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.59669491
108IMP metabolic process (GO:0046040)2.59595268
109RNA catabolic process (GO:0006401)2.59245575
110DNA unwinding involved in DNA replication (GO:0006268)2.56969880
111chromatin remodeling at centromere (GO:0031055)2.56784615
112protein-cofactor linkage (GO:0018065)2.55780742
113pentose-phosphate shunt (GO:0006098)2.55481295
114establishment of protein localization to organelle (GO:0072594)2.54806816
115establishment of viral latency (GO:0019043)2.53857859
116desmosome organization (GO:0002934)2.53444892
1177-methylguanosine mRNA capping (GO:0006370)2.53335280
118nucleoside salvage (GO:0043174)2.52376761
119CENP-A containing nucleosome assembly (GO:0034080)2.51956698
120cullin deneddylation (GO:0010388)2.51596086
121mitochondrial respiratory chain complex assembly (GO:0033108)2.51379086
122regulation of cellular amino acid metabolic process (GO:0006521)2.50985719
123purine nucleobase biosynthetic process (GO:0009113)2.50046684
124positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.48978620
125mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.48978620
126protein complex biogenesis (GO:0070271)2.48825925
127mitotic recombination (GO:0006312)2.47303251
128cellular respiration (GO:0045333)2.44759223
129telomere maintenance via telomere lengthening (GO:0010833)2.43980065
130negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.43840253
131rRNA metabolic process (GO:0016072)2.42965387
132ventricular cardiac muscle cell development (GO:0055015)2.42514427
133rRNA processing (GO:0006364)2.42411387
134proteasome assembly (GO:0043248)2.41933328
135nucleoside triphosphate biosynthetic process (GO:0009142)2.41139916
136pseudouridine synthesis (GO:0001522)2.40637139
137bundle of His cell to Purkinje myocyte communication (GO:0086069)2.39715287
138negative regulation of mitochondrion organization (GO:0010823)2.39268616
139T cell apoptotic process (GO:0070231)2.36703177
140purine nucleoside biosynthetic process (GO:0042451)2.36220099
141purine ribonucleoside biosynthetic process (GO:0046129)2.36220099
142ribosome biogenesis (GO:0042254)2.35236015
143establishment of integrated proviral latency (GO:0075713)2.32232969
144peptidyl-proline hydroxylation (GO:0019511)2.30247214
145nucleoside biosynthetic process (GO:0009163)2.29378971

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.19679335
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.58269062
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.37111834
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.71611236
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.57578808
6TP63_17297297_ChIP-ChIP_HaCaT_Human3.05412233
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.97774883
8MYC_18358816_ChIP-ChIP_MESCs_Mouse2.83392953
9GABP_17652178_ChIP-ChIP_JURKAT_Human2.69619238
10MYC_19079543_ChIP-ChIP_MESCs_Mouse2.66328552
11EST1_17652178_ChIP-ChIP_JURKAT_Human2.60028236
12MYC_19030024_ChIP-ChIP_MESCs_Mouse2.52096663
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.51692959
14* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.49089918
15MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.42421552
16SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.41481168
17ETS1_20019798_ChIP-Seq_JURKAT_Human2.39254668
18HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.30294267
19ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.30050511
20XRN2_22483619_ChIP-Seq_HELA_Human2.29375051
21E2F4_17652178_ChIP-ChIP_JURKAT_Human2.23005401
22E2F1_18555785_ChIP-Seq_MESCs_Mouse2.19871214
23NELFA_20434984_ChIP-Seq_ESCs_Mouse2.12395575
24HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.10211339
25TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.08777016
26FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.06763394
27CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.03911691
28DCP1A_22483619_ChIP-Seq_HELA_Human1.91101803
29ELF1_17652178_ChIP-ChIP_JURKAT_Human1.85942916
30TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.82737234
31VDR_22108803_ChIP-Seq_LS180_Human1.81731672
32TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.80507623
33AR_21909140_ChIP-Seq_LNCAP_Human1.76758196
34VDR_23849224_ChIP-Seq_CD4+_Human1.76503917
35PADI4_21655091_ChIP-ChIP_MCF-7_Human1.72375328
36FUS_26573619_Chip-Seq_HEK293_Human1.71789587
37HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.69182174
38FOXM1_23109430_ChIP-Seq_U2OS_Human1.67897123
39SRF_21415370_ChIP-Seq_HL-1_Mouse1.67499053
40SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.66177958
41ZFX_18555785_ChIP-Seq_MESCs_Mouse1.65620762
42TTF2_22483619_ChIP-Seq_HELA_Human1.64017563
43EWS_26573619_Chip-Seq_HEK293_Human1.60380261
44GABP_19822575_ChIP-Seq_HepG2_Human1.59757627
45STAT3_1855785_ChIP-Seq_MESCs_Mouse1.59300141
46* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.58350481
47HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.58071054
48ZNF274_21170338_ChIP-Seq_K562_Hela1.57452068
49YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.55669898
50TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.52481805
51FOXP3_21729870_ChIP-Seq_TREG_Human1.51775672
52CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.51477204
53IGF1R_20145208_ChIP-Seq_DFB_Human1.50432346
54ELK1_19687146_ChIP-ChIP_HELA_Human1.47762924
55CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.46312873
56NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.46195972
57ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.45681304
58RARG_19884340_ChIP-ChIP_MEFs_Mouse1.45048510
59PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.45022480
60SRY_22984422_ChIP-ChIP_TESTIS_Rat1.39574333
61NANOG_18555785_ChIP-Seq_MESCs_Mouse1.38808464
62FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.38596266
63HOXB4_20404135_ChIP-ChIP_EML_Mouse1.36476858
64THAP11_20581084_ChIP-Seq_MESCs_Mouse1.34462611
65PPARA_22158963_ChIP-Seq_LIVER_Mouse1.33811926
66HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.30290943
67ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.30267305
68POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.29851295
69TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.29740895
70FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.29182425
71E2F1_21310950_ChIP-Seq_MCF-7_Human1.28249454
72MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.27623030
73HIF1A_21447827_ChIP-Seq_MCF-7_Human1.27592919
74* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.26706289
75FLI1_27457419_Chip-Seq_LIVER_Mouse1.25857382
76ERG_20887958_ChIP-Seq_HPC-7_Mouse1.20745353
77MYCN_18555785_ChIP-Seq_MESCs_Mouse1.20645884
78MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.20369338
79POU3F2_20337985_ChIP-ChIP_501MEL_Human1.18769378
80POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.18598371
81EGR1_19374776_ChIP-ChIP_THP-1_Human1.17878207
82CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.17801462
83SOX2_16153702_ChIP-ChIP_HESCs_Human1.17396918
84YY1_21170310_ChIP-Seq_MESCs_Mouse1.17229459
85NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.16494826
86SOX2_18555785_ChIP-Seq_MESCs_Mouse1.14204268
87CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.13240524
88RXR_22158963_ChIP-Seq_LIVER_Mouse1.12567882
89POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.11542378
90PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.11166393
91TAF15_26573619_Chip-Seq_HEK293_Human1.10329806
92NANOG_16153702_ChIP-ChIP_HESCs_Human1.10268016
93POU5F1_16153702_ChIP-ChIP_HESCs_Human1.09476377
94VDR_21846776_ChIP-Seq_THP-1_Human1.09454994
95ELK1_22589737_ChIP-Seq_MCF10A_Human1.08868795
96* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.07839156
97ZNF263_19887448_ChIP-Seq_K562_Human1.06787130
98NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.06404751
99KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.06193261
100IRF1_19129219_ChIP-ChIP_H3396_Human1.05730859
101OCT4_18692474_ChIP-Seq_MEFs_Mouse1.05235120
102CTBP2_25329375_ChIP-Seq_LNCAP_Human1.04701506
103CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.04682105
104P300_19829295_ChIP-Seq_ESCs_Human1.03831061
105SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.03690454
106CLOCK_20551151_ChIP-Seq_293T_Human1.03531537
107RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.02632203
108CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.02351188
109RBPJ_22232070_ChIP-Seq_NCS_Mouse1.00866978
110ATF3_27146783_Chip-Seq_COLON_Human1.00489942
111KLF4_18555785_ChIP-Seq_MESCs_Mouse0.99805751
112MYC_22102868_ChIP-Seq_BL_Human0.99539705
113PCGF2_27294783_Chip-Seq_ESCs_Mouse0.97748481
114MYC_18940864_ChIP-ChIP_HL60_Human0.97099941
115NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.95725459
116SOX17_20123909_ChIP-Seq_XEN_Mouse0.95241182
117SOX2_18692474_ChIP-Seq_MEFs_Mouse0.94434886
118ZFP57_27257070_Chip-Seq_ESCs_Mouse0.94324369
119KDM5A_27292631_Chip-Seq_BREAST_Human0.93864254
120ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.93777934
121FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.92671221
122TBX5_21415370_ChIP-Seq_HL-1_Mouse0.92178720
123TP53_22573176_ChIP-Seq_HFKS_Human0.90773790
124CTBP1_25329375_ChIP-Seq_LNCAP_Human0.90586707
125RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.90349697
126CIITA_25753668_ChIP-Seq_RAJI_Human0.89791116
127KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.88868989
128GATA1_22383799_ChIP-Seq_G1ME_Mouse0.88442746
129ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.86868404
130MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.84975673
131KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.84424144
132ESR1_15608294_ChIP-ChIP_MCF-7_Human0.84145957
133GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.80823335
134FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.80651941
135AR_20517297_ChIP-Seq_VCAP_Human0.79009961
136HTT_18923047_ChIP-ChIP_STHdh_Human0.78855136
137SOX2_19829295_ChIP-Seq_ESCs_Human0.78286611
138NANOG_19829295_ChIP-Seq_ESCs_Human0.78286611
139ERG_20517297_ChIP-Seq_VCAP_Human0.74380189
140RNF2_27304074_Chip-Seq_NSC_Mouse0.74121356
141NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.73712302

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003806_abnormal_nucleotide_metabolis3.46986343
2MP0006292_abnormal_olfactory_placode3.17742706
3MP0003646_muscle_fatigue3.01018016
4MP0004084_abnormal_cardiac_muscle2.98123225
5MP0003136_yellow_coat_color2.63569806
6MP0006072_abnormal_retinal_apoptosis2.54744603
7MP0003880_abnormal_central_pattern2.47911726
8MP0002938_white_spotting2.42529816
9MP0003693_abnormal_embryo_hatching2.42107115
10MP0001529_abnormal_vocalization2.41680853
11MP0004957_abnormal_blastocyst_morpholog2.37489550
12MP0003705_abnormal_hypodermis_morpholog2.36991431
13MP0003122_maternal_imprinting2.34980029
14MP0003186_abnormal_redox_activity2.09730825
15MP0003567_abnormal_fetal_cardiomyocyte2.06723981
16MP0000749_muscle_degeneration1.97740880
17MP0009697_abnormal_copulation1.95916101
18MP0004043_abnormal_pH_regulation1.95831828
19MP0010030_abnormal_orbit_morphology1.88502111
20MP0006036_abnormal_mitochondrial_physio1.85255583
21MP0005330_cardiomyopathy1.84587148
22MP0008775_abnormal_heart_ventricle1.82663906
23MP0006054_spinal_hemorrhage1.81572905
24MP0008438_abnormal_cutaneous_collagen1.76700671
25MP0010352_gastrointestinal_tract_polyps1.75034597
26MP0010234_abnormal_vibrissa_follicle1.74466379
27MP0004215_abnormal_myocardial_fiber1.74185545
28MP0003011_delayed_dark_adaptation1.71143601
29MP0003123_paternal_imprinting1.70067134
30MP0001293_anophthalmia1.63417817
31MP0004145_abnormal_muscle_electrophysio1.57814229
32MP0001984_abnormal_olfaction1.57106570
33MP0003221_abnormal_cardiomyocyte_apopto1.56570785
34MP0005360_urolithiasis1.56313318
35MP0004036_abnormal_muscle_relaxation1.54926915
36MP0003718_maternal_effect1.50724229
37MP0003077_abnormal_cell_cycle1.50062496
38MP0002972_abnormal_cardiac_muscle1.49887268
39MP0000750_abnormal_muscle_regeneration1.48761228
40MP0009379_abnormal_foot_pigmentation1.47451202
41MP0008007_abnormal_cellular_replicative1.47431758
42MP0005385_cardiovascular_system_phenoty1.47177730
43MP0001544_abnormal_cardiovascular_syste1.47177730
44MP0000343_altered_response_to1.47033916
45MP0000566_synostosis1.46484770
46MP0010094_abnormal_chromosome_stability1.45057361
47MP0002090_abnormal_vision1.43726095
48MP0003121_genomic_imprinting1.43055443
49MP0000490_abnormal_crypts_of1.42800659
50MP0002822_catalepsy1.41727794
51MP0001485_abnormal_pinna_reflex1.39792201
52MP0008877_abnormal_DNA_methylation1.39149385
53MP0000537_abnormal_urethra_morphology1.38216282
54MP0005551_abnormal_eye_electrophysiolog1.38044994
55MP0000751_myopathy1.36102683
56MP0005499_abnormal_olfactory_system1.34604805
57MP0005394_taste/olfaction_phenotype1.34604805
58MP0008789_abnormal_olfactory_epithelium1.34552626
59MP0005275_abnormal_skin_tensile1.33793631
60MP0004142_abnormal_muscle_tone1.33643761
61MP0005253_abnormal_eye_physiology1.33403634
62MP0009053_abnormal_anal_canal1.33365745
63MP0004087_abnormal_muscle_fiber1.31600993
64MP0010630_abnormal_cardiac_muscle1.30475464
65MP0004484_altered_response_of1.30431568
66MP0005503_abnormal_tendon_morphology1.29273136
67MP0003937_abnormal_limbs/digits/tail_de1.26429400
68MP0002396_abnormal_hematopoietic_system1.25831994
69MP0002638_abnormal_pupillary_reflex1.25654689
70MP0005266_abnormal_metabolism1.24485728
71MP0008932_abnormal_embryonic_tissue1.24439737
72MP0005365_abnormal_bile_salt1.24033005
73MP0002132_abnormal_respiratory_system1.22708899
74MP0005023_abnormal_wound_healing1.22303864
75MP0003279_aneurysm1.20974422
76MP0005408_hypopigmentation1.20275962
77MP0003878_abnormal_ear_physiology1.19507017
78MP0005377_hearing/vestibular/ear_phenot1.19507017
79MP0003828_pulmonary_edema1.18297701
80MP0005085_abnormal_gallbladder_physiolo1.17811860
81MP0005332_abnormal_amino_acid1.17800234
82MP0001346_abnormal_lacrimal_gland1.17539410
83MP0003566_abnormal_cell_adhesion1.15132312
84MP0001764_abnormal_homeostasis1.14796820
85MP0003195_calcinosis1.14769920
86MP0005084_abnormal_gallbladder_morpholo1.14149497
87MP0002269_muscular_atrophy1.13385862
88MP0003111_abnormal_nucleus_morphology1.13153406
89MP0008995_early_reproductive_senescence1.13011004
90MP0003315_abnormal_perineum_morphology1.11408692
91MP0001286_abnormal_eye_development1.09751738
92MP0006138_congestive_heart_failure1.08962036
93MP0001730_embryonic_growth_arrest1.08359410
94MP0002139_abnormal_hepatobiliary_system1.07167962
95MP0000631_abnormal_neuroendocrine_gland1.06701447
96MP0002697_abnormal_eye_size1.04417752
97MP0008875_abnormal_xenobiotic_pharmacok1.04162902
98MP0004233_abnormal_muscle_weight1.03911011
99MP0002653_abnormal_ependyma_morphology1.03094319
100MP0009384_cardiac_valve_regurgitation1.02482237
101MP0002233_abnormal_nose_morphology1.01779322
102MP0002736_abnormal_nociception_after1.00714327
103MP0002282_abnormal_trachea_morphology1.00194959
104MP0006035_abnormal_mitochondrial_morpho0.99563678
105MP0004133_heterotaxia0.99062647
106MP0003941_abnormal_skin_development0.97781350
107MP0003938_abnormal_ear_development0.96418605
108MP0002837_dystrophic_cardiac_calcinosis0.96387941
109MP0000778_abnormal_nervous_system0.94940982
110MP0009046_muscle_twitch0.94883333
111MP0002160_abnormal_reproductive_system0.93945701
112MP0005319_abnormal_enzyme/_coenzyme0.93746056
113MP0003283_abnormal_digestive_organ0.92211605
114MP0004130_abnormal_muscle_cell0.91708836
115MP0005620_abnormal_muscle_contractility0.91629456
116MP0000350_abnormal_cell_proliferation0.91194223
117MP0000372_irregular_coat_pigmentation0.91038369
118MP0005451_abnormal_body_composition0.90914324
119MP0000647_abnormal_sebaceous_gland0.90833469
120MP0008872_abnormal_physiological_respon0.90789003
121MP0002106_abnormal_muscle_physiology0.90075933
122MP0002163_abnormal_gland_morphology0.88797889
123MP0008058_abnormal_DNA_repair0.88351476
124MP0006276_abnormal_autonomic_nervous0.87404216
125MP0001853_heart_inflammation0.86638659
126MP0002557_abnormal_social/conspecific_i0.85523128
127MP0004019_abnormal_vitamin_homeostasis0.85350775
128MP0002272_abnormal_nervous_system0.84854405
129MP0009333_abnormal_splenocyte_physiolog0.84768520
130MP0003137_abnormal_impulse_conducting0.84582116
131MP0002060_abnormal_skin_morphology0.84244022
132MP0002210_abnormal_sex_determination0.84216407
133MP0000026_abnormal_inner_ear0.83915208
134MP0001697_abnormal_embryo_size0.83551157
135MP0004147_increased_porphyrin_level0.83515774
136MP0003984_embryonic_growth_retardation0.83182370
137MP0000477_abnormal_intestine_morphology0.82754088
138MP0002234_abnormal_pharynx_morphology0.82524006
139MP0002088_abnormal_embryonic_growth/wei0.82375538
140MP0003890_abnormal_embryonic-extraembry0.82106275
141MP0000049_abnormal_middle_ear0.81140457
142MP0005195_abnormal_posterior_eye0.80894563
143MP0010155_abnormal_intestine_physiology0.80600178
144MP0004272_abnormal_basement_membrane0.80276891
145MP0005391_vision/eye_phenotype0.79850750
146MP0005636_abnormal_mineral_homeostasis0.79809077
147MP0002102_abnormal_ear_morphology0.79421820
148MP0002332_abnormal_exercise_endurance0.79242368
149MP0000858_altered_metastatic_potential0.78980132
150MP0002277_abnormal_respiratory_mucosa0.78463769
151MP0004197_abnormal_fetal_growth/weight/0.78306692
152MP0005397_hematopoietic_system_phenotyp0.77601595
153MP0001545_abnormal_hematopoietic_system0.77601595
154MP0004808_abnormal_hematopoietic_stem0.77202905
155MP0000653_abnormal_sex_gland0.76086797
156MP0002080_prenatal_lethality0.75281988
157MP0000759_abnormal_skeletal_muscle0.75036482
158MP0003786_premature_aging0.74573155
159MP0001145_abnormal_male_reproductive0.73312959
160MP0005380_embryogenesis_phenotype0.72678487
161MP0001672_abnormal_embryogenesis/_devel0.72678487
162MP0005187_abnormal_penis_morphology0.72570488
163MP0009785_altered_susceptibility_to0.71693613
164MP0000579_abnormal_nail_morphology0.71302996
165MP0000358_abnormal_cell_content/0.70858405
166MP0002751_abnormal_autonomic_nervous0.70319969
167MP0002752_abnormal_somatic_nervous0.69390407
168MP0005670_abnormal_white_adipose0.68968818
169MP0000762_abnormal_tongue_morphology0.68708991
170MP0002019_abnormal_tumor_incidence0.68520110
171MP0000313_abnormal_cell_death0.67530688
172MP0005165_increased_susceptibility_to0.67459240

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.60342240
2Abnormal mitochondria in muscle tissue (HP:0008316)4.54767104
3Abnormality of cells of the erythroid lineage (HP:0012130)4.21548408
4Abnormal number of erythroid precursors (HP:0012131)4.03700002
5Acute encephalopathy (HP:0006846)4.00659548
6Exercise-induced muscle cramps (HP:0003710)3.96962338
7Hepatic necrosis (HP:0002605)3.81951845
8Rhabdomyolysis (HP:0003201)3.79052508
9Mitochondrial inheritance (HP:0001427)3.76596680
10Progressive macrocephaly (HP:0004481)3.62269468
11Increased CSF lactate (HP:0002490)3.61545941
12Myoglobinuria (HP:0002913)3.58991291
13Reticulocytopenia (HP:0001896)3.54424616
14Hepatocellular necrosis (HP:0001404)3.43070820
15Cerebral edema (HP:0002181)3.37877954
16Decreased activity of mitochondrial respiratory chain (HP:0008972)3.35402155
17Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.35402155
18Exercise intolerance (HP:0003546)3.31653992
19Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.30584470
20Hyperglycinemia (HP:0002154)3.25667599
21Increased serum pyruvate (HP:0003542)3.12674106
22Abnormality of glycolysis (HP:0004366)3.12674106
23Increased muscle lipid content (HP:0009058)3.03766321
24Ventricular tachycardia (HP:0004756)3.02081430
25Increased intramyocellular lipid droplets (HP:0012240)2.99328002
26Lipid accumulation in hepatocytes (HP:0006561)2.93997626
27Conjunctival hamartoma (HP:0100780)2.87228719
28Lactic acidosis (HP:0003128)2.85323066
29Right ventricular cardiomyopathy (HP:0011663)2.83121403
30Dicarboxylic aciduria (HP:0003215)2.81869918
31Abnormality of dicarboxylic acid metabolism (HP:0010995)2.81869918
32Palpitations (HP:0001962)2.79498284
33Hypoglycemic coma (HP:0001325)2.78428913
34Increased hepatocellular lipid droplets (HP:0006565)2.77577886
35Lipoatrophy (HP:0100578)2.77296833
36Respiratory failure (HP:0002878)2.76027653
37Multiple enchondromatosis (HP:0005701)2.74467895
38Increased serum lactate (HP:0002151)2.73698283
39Ragged-red muscle fibers (HP:0003200)2.66799103
40Nausea (HP:0002018)2.65633805
41Medial flaring of the eyebrow (HP:0010747)2.63387203
42Hyperglycinuria (HP:0003108)2.56296316
43Oral leukoplakia (HP:0002745)2.46185607
44Macrocytic anemia (HP:0001972)2.44392124
45Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.43510542
46Protrusio acetabuli (HP:0003179)2.42495031
47Pancreatic cysts (HP:0001737)2.38528959
48Pallor (HP:0000980)2.37011808
49Abnormality of serine family amino acid metabolism (HP:0010894)2.36182304
50Abnormality of glycine metabolism (HP:0010895)2.36182304
51Pancreatic fibrosis (HP:0100732)2.34173896
52Abnormality of serum amino acid levels (HP:0003112)2.32257678
53Abnormal cartilage morphology (HP:0002763)2.31977855
54Congenital primary aphakia (HP:0007707)2.29678214
55X-linked dominant inheritance (HP:0001423)2.28943172
56Type I transferrin isoform profile (HP:0003642)2.28448760
57Sudden death (HP:0001699)2.27631068
58Gait imbalance (HP:0002141)2.25777508
59Cupped ribs (HP:0000887)2.24343472
60Abnormality of fatty-acid metabolism (HP:0004359)2.24231532
61Septo-optic dysplasia (HP:0100842)2.24003199
62Cholecystitis (HP:0001082)2.22720854
63Abnormal gallbladder physiology (HP:0012438)2.22720854
64Abnormality of the 1st metacarpal (HP:0010009)2.18919938
65True hermaphroditism (HP:0010459)2.18549314
66Generalized aminoaciduria (HP:0002909)2.16574195
67Abnormality of reticulocytes (HP:0004312)2.15356165
68Abnormality of methionine metabolism (HP:0010901)2.14566299
69Flat acetabular roof (HP:0003180)2.14380675
70Dilated cardiomyopathy (HP:0001644)2.14221902
71Abnormal tarsal ossification (HP:0008369)2.13620004
72Neoplasm of the adrenal gland (HP:0100631)2.12453692
73Degeneration of anterior horn cells (HP:0002398)2.12418616
74Abnormality of the anterior horn cell (HP:0006802)2.12418616
75Nephrogenic diabetes insipidus (HP:0009806)2.10369265
76Methylmalonic acidemia (HP:0002912)2.09518192
77Irregular epiphyses (HP:0010582)2.08110052
78Methylmalonic aciduria (HP:0012120)2.06755363
79Abnormality of renal resorption (HP:0011038)2.06510360
80Colon cancer (HP:0003003)2.06075438
81Lethargy (HP:0001254)2.04060221
82Myokymia (HP:0002411)2.03797172
83Aplastic anemia (HP:0001915)2.00546470
84Exertional dyspnea (HP:0002875)1.98881828
85Abnormality of midbrain morphology (HP:0002418)1.97640174
86Molar tooth sign on MRI (HP:0002419)1.97640174
87Hyperinsulinemic hypoglycemia (HP:0000825)1.96816901
88Hyperphosphaturia (HP:0003109)1.96664302
89Microretrognathia (HP:0000308)1.96510511
90Optic disc pallor (HP:0000543)1.94536097
91Respiratory difficulties (HP:0002880)1.93424384
92Reduced antithrombin III activity (HP:0001976)1.93393318
93Abnormality of aspartate family amino acid metabolism (HP:0010899)1.93174356
94Hyperammonemia (HP:0001987)1.92184384
95Abnormality of carpal bone ossification (HP:0006257)1.92052754
96Muscle stiffness (HP:0003552)1.91196800
97Trismus (HP:0000211)1.90620212
98Congenital, generalized hypertrichosis (HP:0004540)1.87807012
99Vaginal atresia (HP:0000148)1.87745298
100Abnormality of the labia minora (HP:0012880)1.85736187
101Meckel diverticulum (HP:0002245)1.85496832
102Neoplasm of head and neck (HP:0012288)1.84216421
103Esophageal neoplasm (HP:0100751)1.84216421
104Genital tract atresia (HP:0001827)1.83564517
105Abnormality of the ileum (HP:0001549)1.82740589
106Supernumerary spleens (HP:0009799)1.76454098
107Type 1 muscle fiber predominance (HP:0003803)1.74667582
108Beaking of vertebral bodies (HP:0004568)1.73183127
109Breech presentation (HP:0001623)1.72433491
110Partial duplication of thumb phalanx (HP:0009944)1.72239598
111Blindness (HP:0000618)1.72103485
112Leukodystrophy (HP:0002415)1.70913771
113Supraventricular tachycardia (HP:0004755)1.70628851
114Thrombocytosis (HP:0001894)1.70356653
115Triphalangeal thumb (HP:0001199)1.68979782
116Stenosis of the external auditory canal (HP:0000402)1.68646644
117Atrial fibrillation (HP:0005110)1.68511466
118Adenoma sebaceum (HP:0009720)1.68472919
119Angiofibromas (HP:0010615)1.68472919
120Abnormal biliary tract physiology (HP:0012439)1.67512341
121Bile duct proliferation (HP:0001408)1.67512341
122Supraventricular arrhythmia (HP:0005115)1.66807304
123Glycosuria (HP:0003076)1.66041967
124Abnormality of urine glucose concentration (HP:0011016)1.66041967
125Neonatal short-limb short stature (HP:0008921)1.65422445
126Renal cortical cysts (HP:0000803)1.63788850
1273-Methylglutaconic aciduria (HP:0003535)1.62817231
128Gliosis (HP:0002171)1.62546862
129Gout (HP:0001997)1.62216997
130Absent septum pellucidum (HP:0001331)1.61013867
131Vomiting (HP:0002013)1.60947106
132Renal tubular dysfunction (HP:0000124)1.60791204
133Abnormality of the 2nd finger (HP:0004100)1.60615516
134Sclerocornea (HP:0000647)1.59154336
135Renal Fanconi syndrome (HP:0001994)1.59146358
136Abnormality of the left ventricular outflow tract (HP:0011103)1.59011840
137Subaortic stenosis (HP:0001682)1.59011840
138Neoplasm of the rectum (HP:0100743)1.58635875
139CNS demyelination (HP:0007305)1.57494798
140Primary atrial arrhythmia (HP:0001692)1.55245690
141Sparse eyelashes (HP:0000653)1.54480325
142Aplasia/Hypoplasia of the sacrum (HP:0008517)1.54191054
143Abnormality of the heme biosynthetic pathway (HP:0010472)1.53856945
144Abnormality of the calf musculature (HP:0001430)1.53794601
145Hyperalaninemia (HP:0003348)1.52212946
146Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.52212946
147Abnormality of alanine metabolism (HP:0010916)1.52212946
148Emotional lability (HP:0000712)1.51802464

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME24.53488059
2VRK24.15405065
3PKN23.42779568
4TESK12.51313973
5EIF2AK12.40192422
6FLT32.37713045
7MYLK2.33940828
8NEK12.32856896
9TNIK2.30881654
10BCKDK2.28980271
11MST1R2.28816127
12PIK3CA2.16788403
13OBSCN2.12108405
14WEE12.12037540
15PIM22.01140146
16BUB11.97687320
17CDK191.96093307
18MST41.95780642
19CCNB11.95406867
20PDK21.94308699
21WNK31.91815280
22LIMK11.88870667
23TESK21.85541483
24BMPR1B1.82470872
25MAP4K21.80778101
26KDR1.77902502
27TAF11.72775601
28PLK31.65002203
29TTN1.60162436
30SCYL21.55216185
31RPS6KB21.49420100
32RPS6KA41.48258943
33MAP3K111.47784599
34WNK41.47125694
35ERN11.46254378
36CASK1.46071201
37TRIB31.44940910
38NUAK11.41647712
39STK161.40771497
40EPHA41.40659000
41BRSK21.38506883
42TAOK21.38436849
43DYRK21.35893123
44NME11.35075550
45CDC71.34284015
46ILK1.33666038
47MAP3K121.30658271
48STK241.28406455
49ZAK1.27671586
50LRRK21.26915911
51STK391.24573572
52PBK1.17698541
53TRIM281.16147345
54TGFBR11.14498393
55MAP3K31.13500531
56AURKB1.13296038
57EIF2AK31.12683452
58MAP2K31.12181085
59NEK21.08478675
60PAK41.08357643
61BCR1.07881920
62TLK11.06819506
63ACVR1B1.06761736
64VRK11.06089013
65GRK11.05690945
66MAP3K81.01105576
67NEK90.99745734
68EPHB20.99131125
69MAPKAPK30.96081153
70MAP3K40.94737948
71CDK70.92811529
72CSNK1G20.92500353
73TEC0.90200127
74LATS20.90043561
75DAPK30.89214573
76TTK0.88391945
77PINK10.87652426
78INSRR0.86830402
79PLK40.86625125
80PDK30.86093193
81PDK40.86093193
82ARAF0.86091885
83STK38L0.86026093
84ERBB30.85527529
85PLK10.84780480
86MAP3K70.83083998
87OXSR10.83028943
88MKNK20.82033240
89PRKG20.81736857
90CSNK1G30.79658370
91PHKG20.78754986
92PHKG10.78754986
93PLK20.76450527
94FGFR20.74677803
95CSNK2A20.74392201
96PRKCG0.73045372
97PAK10.72978473
98CSNK1G10.72831765
99CDK80.72442372
100MET0.72227070
101CDK40.72157228
102LMTK20.72093537
103MOS0.71919713
104ABL20.69708391
105STK100.66258756
106SRPK10.64566604
107BRAF0.63558029
108MAP3K100.60535194
109MAP2K20.58567913
110AURKA0.58485593
111STK40.57611099
112ATR0.57575098
113PIM10.57474993
114STK30.56602127
115AKT20.56114568
116TYK20.56057501
117MAP3K50.55981630
118PNCK0.55701937
119MAP2K70.55634827
120BLK0.55336411
121TSSK60.55295509
122CSNK1A1L0.54549627
123DYRK30.54023208
124BRSK10.53931750
125PIK3CG0.52874074
126EPHA20.52209756
127PAK30.52038239
128EEF2K0.51110740
129PRKCE0.50758454
130MKNK10.50415827
131CSNK1E0.49873680
132CHEK20.48405789
133PASK0.48363548
134PAK20.48213729
135RAF10.48098459
136CSNK2A10.47967463
137RPS6KA50.45178462
138FGFR10.44698112
139MARK30.43760457
140MAP2K60.43449430
141RIPK10.42655603
142MAPK110.41737166
143CSNK1A10.41619804
144CAMKK20.41537114
145EIF2AK20.41523118
146MUSK0.41443419
147NTRK20.41371739
148ADRBK20.40246440
149FRK0.39398955
150MAPKAPK50.39089145
151NLK0.38990247
152MARK10.36733191
153MAPK130.34091585
154ATM0.31809551
155CDK11A0.31414443
156PRKACA0.30384085

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.11447701
2Parkinsons disease_Homo sapiens_hsa050123.22345504
3Oxidative phosphorylation_Homo sapiens_hsa001903.17760842
4Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.04640377
5DNA replication_Homo sapiens_hsa030302.99489779
6Proteasome_Homo sapiens_hsa030502.50181807
7Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.29974328
8Huntingtons disease_Homo sapiens_hsa050162.27745635
9Mismatch repair_Homo sapiens_hsa034302.20082651
10Carbon metabolism_Homo sapiens_hsa012002.15167984
11Alzheimers disease_Homo sapiens_hsa050102.09613624
122-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.02112456
13Sulfur metabolism_Homo sapiens_hsa009202.01446410
14Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.93561121
15Cardiac muscle contraction_Homo sapiens_hsa042601.90891059
16Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.80042052
17RNA polymerase_Homo sapiens_hsa030201.78864262
18Biosynthesis of amino acids_Homo sapiens_hsa012301.76388156
19Pyrimidine metabolism_Homo sapiens_hsa002401.75777782
20One carbon pool by folate_Homo sapiens_hsa006701.73558149
21Base excision repair_Homo sapiens_hsa034101.66531061
22Propanoate metabolism_Homo sapiens_hsa006401.57326950
23Homologous recombination_Homo sapiens_hsa034401.50835658
24Spliceosome_Homo sapiens_hsa030401.47524614
25Pentose phosphate pathway_Homo sapiens_hsa000301.46789359
26Nucleotide excision repair_Homo sapiens_hsa034201.44516948
27Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.43553370
28Galactose metabolism_Homo sapiens_hsa000521.41440529
29Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.40659983
30Sulfur relay system_Homo sapiens_hsa041221.35132109
31Fatty acid degradation_Homo sapiens_hsa000711.34966428
32Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.34747991
33Pyruvate metabolism_Homo sapiens_hsa006201.34664606
34Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.33875382
35Fructose and mannose metabolism_Homo sapiens_hsa000511.31592382
36Fatty acid elongation_Homo sapiens_hsa000621.27705450
37Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.24229968
38Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.22705168
39Drug metabolism - other enzymes_Homo sapiens_hsa009831.19972904
40Cysteine and methionine metabolism_Homo sapiens_hsa002701.19515147
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.19396976
42Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.18496895
43Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.10990249
44RNA transport_Homo sapiens_hsa030131.10281632
45Folate biosynthesis_Homo sapiens_hsa007901.08021322
46Pentose and glucuronate interconversions_Homo sapiens_hsa000401.06082617
47Nitrogen metabolism_Homo sapiens_hsa009101.02789128
48Steroid biosynthesis_Homo sapiens_hsa001001.02775923
49Glutathione metabolism_Homo sapiens_hsa004801.00589662
50Selenocompound metabolism_Homo sapiens_hsa004500.97385394
51Starch and sucrose metabolism_Homo sapiens_hsa005000.97304911
52Vitamin B6 metabolism_Homo sapiens_hsa007500.96364516
53Cell cycle_Homo sapiens_hsa041100.94564452
54Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.93158265
55p53 signaling pathway_Homo sapiens_hsa041150.92154845
56Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.92126811
57Legionellosis_Homo sapiens_hsa051340.88944349
58RNA degradation_Homo sapiens_hsa030180.85632455
59Maturity onset diabetes of the young_Homo sapiens_hsa049500.85629305
60Phenylalanine metabolism_Homo sapiens_hsa003600.83154453
61Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.81300483
62Protein export_Homo sapiens_hsa030600.81268895
63Central carbon metabolism in cancer_Homo sapiens_hsa052300.79047026
64Purine metabolism_Homo sapiens_hsa002300.78305483
65Chemical carcinogenesis_Homo sapiens_hsa052040.77742968
66Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.74739091
67Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.73146318
68Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.72390151
69Peroxisome_Homo sapiens_hsa041460.71958534
70Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.71823412
71Metabolic pathways_Homo sapiens_hsa011000.70839281
72HIF-1 signaling pathway_Homo sapiens_hsa040660.70395612
73Fat digestion and absorption_Homo sapiens_hsa049750.69667933
74Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.67323169
75Linoleic acid metabolism_Homo sapiens_hsa005910.66938990
76Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.65463424
77Collecting duct acid secretion_Homo sapiens_hsa049660.65462861
78Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.65194022
79alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.64293572
80Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.63104286
81Fatty acid metabolism_Homo sapiens_hsa012120.61653126
82Tyrosine metabolism_Homo sapiens_hsa003500.61650931
83Vitamin digestion and absorption_Homo sapiens_hsa049770.60576483
84Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.59580907
85Non-homologous end-joining_Homo sapiens_hsa034500.58978257
86Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.57216657
87Cyanoamino acid metabolism_Homo sapiens_hsa004600.53528851
88Arginine and proline metabolism_Homo sapiens_hsa003300.53478928
89Systemic lupus erythematosus_Homo sapiens_hsa053220.52303235
90Thyroid cancer_Homo sapiens_hsa052160.52171464
91Caffeine metabolism_Homo sapiens_hsa002320.50885120
92Mineral absorption_Homo sapiens_hsa049780.50338356
93PPAR signaling pathway_Homo sapiens_hsa033200.50197431
94Phototransduction_Homo sapiens_hsa047440.49213177
95Arachidonic acid metabolism_Homo sapiens_hsa005900.47765370
96Steroid hormone biosynthesis_Homo sapiens_hsa001400.45939097
97Tryptophan metabolism_Homo sapiens_hsa003800.44400499
98Primary bile acid biosynthesis_Homo sapiens_hsa001200.43117816
99Retinol metabolism_Homo sapiens_hsa008300.41345848
100Bladder cancer_Homo sapiens_hsa052190.41006335
101N-Glycan biosynthesis_Homo sapiens_hsa005100.37292748
102Nicotine addiction_Homo sapiens_hsa050330.35212308
103Antigen processing and presentation_Homo sapiens_hsa046120.35198101
104beta-Alanine metabolism_Homo sapiens_hsa004100.34922799
105Arginine biosynthesis_Homo sapiens_hsa002200.34789713
106Fanconi anemia pathway_Homo sapiens_hsa034600.33575758
107Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.29950866
108Butanoate metabolism_Homo sapiens_hsa006500.29941523
109Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.29232673
110mRNA surveillance pathway_Homo sapiens_hsa030150.28959903
111Oocyte meiosis_Homo sapiens_hsa041140.28764564
112Viral myocarditis_Homo sapiens_hsa054160.28279422
113Dilated cardiomyopathy_Homo sapiens_hsa054140.27410029
114Basal transcription factors_Homo sapiens_hsa030220.26881498
115Regulation of autophagy_Homo sapiens_hsa041400.26811615
116Circadian rhythm_Homo sapiens_hsa047100.26593700
117Small cell lung cancer_Homo sapiens_hsa052220.24677796
118Epstein-Barr virus infection_Homo sapiens_hsa051690.22631608
119Herpes simplex infection_Homo sapiens_hsa051680.21678705
120TGF-beta signaling pathway_Homo sapiens_hsa043500.21572013
121Apoptosis_Homo sapiens_hsa042100.21529293

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