FAM161B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)4.59314823
2central nervous system myelination (GO:0022010)4.59314823
3behavioral response to nicotine (GO:0035095)4.43298089
4cilium or flagellum-dependent cell motility (GO:0001539)4.41002331
5neuron cell-cell adhesion (GO:0007158)4.39851764
6startle response (GO:0001964)4.38549226
7presynaptic membrane assembly (GO:0097105)4.37203297
8axonemal dynein complex assembly (GO:0070286)4.32324769
9long-chain fatty acid biosynthetic process (GO:0042759)4.31203557
10presynaptic membrane organization (GO:0097090)4.18049703
11ionotropic glutamate receptor signaling pathway (GO:0035235)3.92129288
12cilium movement (GO:0003341)3.87317694
13epithelial cilium movement (GO:0003351)3.86486697
14glutamate receptor signaling pathway (GO:0007215)3.70750579
15pyrimidine nucleobase catabolic process (GO:0006208)3.68627257
16cellular ketone body metabolic process (GO:0046950)3.63047152
17L-amino acid import (GO:0043092)3.51640089
18synaptic transmission, glutamatergic (GO:0035249)3.49956417
19protein localization to synapse (GO:0035418)3.46963990
20postsynaptic membrane organization (GO:0001941)3.44715885
21negative regulation of synaptic transmission, GABAergic (GO:0032229)3.41940841
22neuron recognition (GO:0008038)3.30864626
23neuron-neuron synaptic transmission (GO:0007270)3.28786197
24sperm motility (GO:0030317)3.23673702
25protein polyglutamylation (GO:0018095)3.23593527
26epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.22705271
27eye photoreceptor cell differentiation (GO:0001754)3.22645944
28photoreceptor cell differentiation (GO:0046530)3.22645944
29ketone body metabolic process (GO:1902224)3.21621940
30regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.19455938
31nucleobase catabolic process (GO:0046113)3.17037477
32protein localization to cilium (GO:0061512)3.16262461
33axoneme assembly (GO:0035082)3.15847745
34regulation of action potential (GO:0098900)3.15676451
35G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.14989215
36water-soluble vitamin biosynthetic process (GO:0042364)3.14736077
37transmission of nerve impulse (GO:0019226)3.14592382
38regulation of microtubule-based movement (GO:0060632)3.14396992
39retinal cone cell development (GO:0046549)3.11203302
40positive regulation of action potential (GO:0045760)3.10102686
41limb bud formation (GO:0060174)3.09664278
42cerebral cortex radially oriented cell migration (GO:0021799)3.08946381
43fucose catabolic process (GO:0019317)3.08157845
44L-fucose metabolic process (GO:0042354)3.08157845
45L-fucose catabolic process (GO:0042355)3.08157845
46protein complex biogenesis (GO:0070271)3.06266608
47vocalization behavior (GO:0071625)3.04845259
48mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.02766847
49positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.00772959
50negative regulation of cytosolic calcium ion concentration (GO:0051481)2.99465988
51piRNA metabolic process (GO:0034587)2.97339260
52regulation of respiratory system process (GO:0044065)2.97152623
53neuronal action potential propagation (GO:0019227)2.97076236
54regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.96654229
55cilium morphogenesis (GO:0060271)2.95584361
56intraciliary transport (GO:0042073)2.94766415
57motile cilium assembly (GO:0044458)2.93762721
58membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.92965483
59gamma-aminobutyric acid transport (GO:0015812)2.92627019
60nonmotile primary cilium assembly (GO:0035058)2.90965090
61mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.88388055
62mitochondrial respiratory chain complex I assembly (GO:0032981)2.88388055
63NADH dehydrogenase complex assembly (GO:0010257)2.88388055
64positive regulation of synapse assembly (GO:0051965)2.87362241
65regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.86024703
66gamma-aminobutyric acid signaling pathway (GO:0007214)2.86002030
67indolalkylamine metabolic process (GO:0006586)2.82599207
68axonal fasciculation (GO:0007413)2.81996042
69regulation of respiratory gaseous exchange (GO:0043576)2.81804203
70response to redox state (GO:0051775)2.81800861
71neurotransmitter uptake (GO:0001504)2.79530012
72righting reflex (GO:0060013)2.79104503
73mitochondrial respiratory chain complex assembly (GO:0033108)2.78241275
74regulation of short-term neuronal synaptic plasticity (GO:0048172)2.77593207
75membrane depolarization during action potential (GO:0086010)2.77415581
76neuronal action potential (GO:0019228)2.73345963
77protein-cofactor linkage (GO:0018065)2.71668758
78establishment of protein localization to Golgi (GO:0072600)2.71640150
79centriole replication (GO:0007099)2.71469836
80positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.71106366
81regulation of synapse structural plasticity (GO:0051823)2.70790729
82dendritic spine morphogenesis (GO:0060997)2.69677465
83platelet dense granule organization (GO:0060155)2.69634683
84negative regulation of axon guidance (GO:1902668)2.67996152
85C4-dicarboxylate transport (GO:0015740)2.67262640
86synaptic vesicle exocytosis (GO:0016079)2.66651384
87cilium assembly (GO:0042384)2.66574019
88acrosome reaction (GO:0007340)2.66520104
89regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.66042579
90behavioral response to cocaine (GO:0048148)2.63407130
91response to auditory stimulus (GO:0010996)2.62432053
92positive regulation of neurotransmitter secretion (GO:0001956)2.62366383
93neuromuscular synaptic transmission (GO:0007274)2.62326540
94regulation of rhodopsin mediated signaling pathway (GO:0022400)2.61793782
95regulation of catecholamine metabolic process (GO:0042069)2.60755495
96regulation of dopamine metabolic process (GO:0042053)2.60755495
97synapse assembly (GO:0007416)2.60540129
98cilium organization (GO:0044782)2.60286927
99negative regulation of neurotransmitter transport (GO:0051589)2.59004994
100protein targeting to Golgi (GO:0000042)2.57878223
101keratinocyte development (GO:0003334)2.57503143
102regulation of glutamate receptor signaling pathway (GO:1900449)2.57316250
103regulation of voltage-gated calcium channel activity (GO:1901385)2.56958673
104multicellular organism reproduction (GO:0032504)2.56817835
105behavioral response to ethanol (GO:0048149)2.56758628
106amino acid import (GO:0043090)2.55999871
107detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.55427738
108indole-containing compound catabolic process (GO:0042436)2.55042908
109indolalkylamine catabolic process (GO:0046218)2.55042908
110tryptophan catabolic process (GO:0006569)2.55042908
111negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.54485981
112retina layer formation (GO:0010842)2.54139296
113synapsis (GO:0007129)2.51739618
114establishment of protein localization to mitochondrial membrane (GO:0090151)2.51247246
115urinary tract smooth muscle contraction (GO:0014848)2.50933866
116detection of calcium ion (GO:0005513)2.50875276
117neurotransmitter-gated ion channel clustering (GO:0072578)2.50711134
118brain morphogenesis (GO:0048854)2.49312279
119regulation of neurotransmitter uptake (GO:0051580)2.48710394
120mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.47962843
121tryptophan metabolic process (GO:0006568)2.47878847
122negative regulation of appetite (GO:0032099)2.47271606
123negative regulation of response to food (GO:0032096)2.47271606
124rhodopsin mediated signaling pathway (GO:0016056)2.47191505
125positive regulation of synaptic transmission, GABAergic (GO:0032230)2.47073425
126retinal ganglion cell axon guidance (GO:0031290)2.47038550
127mechanosensory behavior (GO:0007638)2.46992192
128regulation of feeding behavior (GO:0060259)2.46574345
129glycerophospholipid catabolic process (GO:0046475)2.46252565
130positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.46033826
131protein localization to Golgi apparatus (GO:0034067)2.45876337
132energy coupled proton transport, down electrochemical gradient (GO:0015985)2.45592614
133ATP synthesis coupled proton transport (GO:0015986)2.45592614
134auditory behavior (GO:0031223)2.45284136
135photoreceptor cell maintenance (GO:0045494)2.45015426
136synaptic transmission, cholinergic (GO:0007271)2.44462114
137synaptic vesicle endocytosis (GO:0048488)2.44097138
138central nervous system projection neuron axonogenesis (GO:0021952)2.44003206
139detection of light stimulus involved in sensory perception (GO:0050962)2.43119236
140detection of light stimulus involved in visual perception (GO:0050908)2.43119236
141response to histamine (GO:0034776)2.42411114
142regulation of neurotransmitter secretion (GO:0046928)2.41857868
143microtubule depolymerization (GO:0007019)2.41758282
144adult behavior (GO:0030534)2.41625772
145regulation of synaptic vesicle exocytosis (GO:2000300)2.41125577
146adult locomotory behavior (GO:0008344)2.40330410
147electron transport chain (GO:0022900)2.39445207
148regulation of cilium movement (GO:0003352)2.39000581
149adult walking behavior (GO:0007628)2.38700755
150sensory perception of smell (GO:0007608)2.38034621
151calcium ion-dependent exocytosis (GO:0017156)2.37820286
152calcium-mediated signaling using intracellular calcium source (GO:0035584)2.37642778
153membrane hyperpolarization (GO:0060081)2.36932299
154positive regulation of neurotransmitter transport (GO:0051590)2.36812888
155regulation of vesicle fusion (GO:0031338)2.36569300
156regulation of cell communication by electrical coupling (GO:0010649)2.36557599
157response to pheromone (GO:0019236)2.35704282

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.33707981
2GBX2_23144817_ChIP-Seq_PC3_Human3.83209217
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.94107441
4ZFP57_27257070_Chip-Seq_ESCs_Mouse2.61500280
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.49326362
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.30919316
7GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.29358070
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.27812562
9FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.21908345
10SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.21167057
11CBX2_27304074_Chip-Seq_ESCs_Mouse2.21057990
12BMI1_23680149_ChIP-Seq_NPCS_Mouse2.14481335
13TAF15_26573619_Chip-Seq_HEK293_Human2.05745509
14POU3F2_20337985_ChIP-ChIP_501MEL_Human2.02644941
15GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.01983555
16EED_16625203_ChIP-ChIP_MESCs_Mouse2.00364213
17SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.99741656
18REST_21632747_ChIP-Seq_MESCs_Mouse1.94654388
19PCGF2_27294783_Chip-Seq_ESCs_Mouse1.91757710
20SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.91222063
21CTBP1_25329375_ChIP-Seq_LNCAP_Human1.90617580
22JARID2_20075857_ChIP-Seq_MESCs_Mouse1.87708996
23RNF2_18974828_ChIP-Seq_MESCs_Mouse1.87252395
24EZH2_18974828_ChIP-Seq_MESCs_Mouse1.87252395
25FLI1_27457419_Chip-Seq_LIVER_Mouse1.85741720
26SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.85472841
27P300_19829295_ChIP-Seq_ESCs_Human1.84425809
28EZH2_27294783_Chip-Seq_ESCs_Mouse1.82739339
29RNF2_27304074_Chip-Seq_NSC_Mouse1.81028439
30CTBP2_25329375_ChIP-Seq_LNCAP_Human1.79316097
31RNF2_27304074_Chip-Seq_ESCs_Mouse1.74193366
32CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.73132534
33SUZ12_27294783_Chip-Seq_ESCs_Mouse1.72567704
34PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.70682513
35SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.70010405
36FUS_26573619_Chip-Seq_HEK293_Human1.68518950
37* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.63746836
38VDR_22108803_ChIP-Seq_LS180_Human1.62017604
39NANOG_18555785_Chip-Seq_ESCs_Mouse1.61565709
40SUZ12_27294783_Chip-Seq_NPCs_Mouse1.60534137
41MTF2_20144788_ChIP-Seq_MESCs_Mouse1.60448546
42TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.58377399
43SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.58362156
44SMAD4_21799915_ChIP-Seq_A2780_Human1.57714858
45IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.56739897
46CBP_20019798_ChIP-Seq_JUKART_Human1.56739897
47SMAD3_21741376_ChIP-Seq_EPCs_Human1.55995403
48EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.50532596
49ER_23166858_ChIP-Seq_MCF-7_Human1.48363083
50E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.48019785
51NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.47994928
52NFE2_27457419_Chip-Seq_LIVER_Mouse1.45843888
53PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.45843555
54RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.44869883
55DROSHA_22980978_ChIP-Seq_HELA_Human1.44760568
56PIAS1_25552417_ChIP-Seq_VCAP_Human1.41307289
57E2F1_18555785_Chip-Seq_ESCs_Mouse1.41232815
58PCGF2_27294783_Chip-Seq_NPCs_Mouse1.40499591
59SUZ12_18555785_Chip-Seq_ESCs_Mouse1.39243036
60P53_22387025_ChIP-Seq_ESCs_Mouse1.39111237
61CMYC_18555785_Chip-Seq_ESCs_Mouse1.38704248
62CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38603917
63TP53_22573176_ChIP-Seq_HFKS_Human1.37006601
64BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.36655702
65CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.36150706
66EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.35984992
67AR_21572438_ChIP-Seq_LNCaP_Human1.35937876
68MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.34986889
69EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.34471056
70SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.33525929
71TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.32974389
72POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.32974389
73TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32947341
74STAT3_18555785_Chip-Seq_ESCs_Mouse1.31887706
75UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.30879104
76CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.29991984
77P300_18555785_Chip-Seq_ESCs_Mouse1.28704746
78OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.27612733
79KLF5_20875108_ChIP-Seq_MESCs_Mouse1.27603585
80REST_18959480_ChIP-ChIP_MESCs_Mouse1.27366358
81ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.27196550
82EZH2_27294783_Chip-Seq_NPCs_Mouse1.26978477
83NANOG_19829295_ChIP-Seq_ESCs_Human1.25856577
84SOX2_19829295_ChIP-Seq_ESCs_Human1.25856577
85SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.25696771
86GABP_17652178_ChIP-ChIP_JURKAT_Human1.25540398
87ETV2_25802403_ChIP-Seq_MESCs_Mouse1.25411215
88BCAT_22108803_ChIP-Seq_LS180_Human1.24764702
89SOX2_18555785_Chip-Seq_ESCs_Mouse1.23634343
90IRF1_19129219_ChIP-ChIP_H3396_Human1.23525466
91TAL1_26923725_Chip-Seq_HPCs_Mouse1.22786271
92RUNX1_27457419_Chip-Seq_LIVER_Mouse1.21684036
93GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.21668787
94* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.21261312
95MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.20420341
96NMYC_18555785_Chip-Seq_ESCs_Mouse1.19726659
97POU5F1_16153702_ChIP-ChIP_HESCs_Human1.18119704
98IGF1R_20145208_ChIP-Seq_DFB_Human1.18106786
99CDX2_19796622_ChIP-Seq_MESCs_Mouse1.18020785
100TCF4_23295773_ChIP-Seq_U87_Human1.15200236
101OCT4_18555785_Chip-Seq_ESCs_Mouse1.14554656
102MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.14528928
103PRDM14_20953172_ChIP-Seq_ESCs_Human1.14029004
104TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13941120
105EWS_26573619_Chip-Seq_HEK293_Human1.13045617
106P53_22127205_ChIP-Seq_FIBROBLAST_Human1.12884869
107SMAD4_21741376_ChIP-Seq_EPCs_Human1.12291926
108STAT3_23295773_ChIP-Seq_U87_Human1.12278851
109EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.11671537
110KLF4_18555785_Chip-Seq_ESCs_Mouse1.11529527
111ZNF274_21170338_ChIP-Seq_K562_Hela1.11519483
112AR_25329375_ChIP-Seq_VCAP_Human1.11371489
113RUNX2_22187159_ChIP-Seq_PCA_Human1.10495313
114TCF4_22108803_ChIP-Seq_LS180_Human1.10180363
115ZFX_18555785_Chip-Seq_ESCs_Mouse1.09344093
116AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.08763403
117TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.07522124
118PU1_27457419_Chip-Seq_LIVER_Mouse1.07385478
119FLI1_21867929_ChIP-Seq_TH2_Mouse1.05890936
120MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05581814
121CTCF_18555785_Chip-Seq_ESCs_Mouse1.05456659
122LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.05342558
123NCOR_22424771_ChIP-Seq_293T_Human1.04222312
124SOX2_21211035_ChIP-Seq_LN229_Gbm1.03604481
125MYC_18940864_ChIP-ChIP_HL60_Human1.02045645
126FOXA1_25329375_ChIP-Seq_VCAP_Human1.01150335
127FOXA1_27270436_Chip-Seq_PROSTATE_Human1.01150335
128GATA3_21878914_ChIP-Seq_MCF-7_Human0.99588962

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.57075426
2MP0005423_abnormal_somatic_nervous3.02639471
3MP0001188_hyperpigmentation2.93465626
4MP0004859_abnormal_synaptic_plasticity2.59772625
5MP0001486_abnormal_startle_reflex2.58069057
6MP0005645_abnormal_hypothalamus_physiol2.55808789
7MP0009046_muscle_twitch2.54484000
8MP0001984_abnormal_olfaction2.50335607
9MP0003635_abnormal_synaptic_transmissio2.47641173
10MP0003136_yellow_coat_color2.38393226
11MP0009745_abnormal_behavioral_response2.36506050
12MP0000566_synostosis2.31769160
13MP0005551_abnormal_eye_electrophysiolog2.29330541
14MP0002272_abnormal_nervous_system2.29252417
15MP0004270_analgesia2.27889343
16MP0006276_abnormal_autonomic_nervous2.26203311
17MP0005409_darkened_coat_color2.24084897
18MP0002064_seizures2.23307249
19MP0001529_abnormal_vocalization2.21579308
20MP0006292_abnormal_olfactory_placode2.21490897
21MP0000778_abnormal_nervous_system2.05435538
22MP0002063_abnormal_learning/memory/cond2.03406269
23MP0002572_abnormal_emotion/affect_behav2.03400621
24MP0002734_abnormal_mechanical_nocicepti1.96520828
25MP0002822_catalepsy1.87848533
26MP0002638_abnormal_pupillary_reflex1.87815049
27MP0005646_abnormal_pituitary_gland1.85910633
28MP0010386_abnormal_urinary_bladder1.82723305
29MP0003787_abnormal_imprinting1.77433148
30MP0008877_abnormal_DNA_methylation1.76912703
31MP0001968_abnormal_touch/_nociception1.76219504
32MP0001905_abnormal_dopamine_level1.74193568
33MP0005410_abnormal_fertilization1.71540142
34MP0000569_abnormal_digit_pigmentation1.68951140
35MP0001986_abnormal_taste_sensitivity1.67315753
36MP0002067_abnormal_sensory_capabilities1.65791620
37MP0002735_abnormal_chemical_nociception1.65529013
38MP0004742_abnormal_vestibular_system1.61667600
39MP0006072_abnormal_retinal_apoptosis1.58262721
40MP0002184_abnormal_innervation1.56527437
41MP0003195_calcinosis1.56277816
42MP0002557_abnormal_social/conspecific_i1.53622452
43MP0002653_abnormal_ependyma_morphology1.51427138
44MP0004142_abnormal_muscle_tone1.51048439
45MP0001502_abnormal_circadian_rhythm1.48861187
46MP0001440_abnormal_grooming_behavior1.48641338
47MP0002736_abnormal_nociception_after1.48404287
48MP0005171_absent_coat_pigmentation1.39208290
49MP0001501_abnormal_sleep_pattern1.37749059
50MP0002882_abnormal_neuron_morphology1.35588973
51MP0008875_abnormal_xenobiotic_pharmacok1.34226591
52MP0002163_abnormal_gland_morphology1.33433809
53MP0002102_abnormal_ear_morphology1.33418207
54MP0001970_abnormal_pain_threshold1.32856475
55MP0000631_abnormal_neuroendocrine_gland1.31399530
56MP0000920_abnormal_myelination1.31395450
57MP0004924_abnormal_behavior1.31332146
58MP0005386_behavior/neurological_phenoty1.31332146
59MP0001485_abnormal_pinna_reflex1.29919729
60MP0005253_abnormal_eye_physiology1.28430041
61MP0002752_abnormal_somatic_nervous1.23804738
62MP0003646_muscle_fatigue1.23036040
63MP0002229_neurodegeneration1.21392466
64MP0004381_abnormal_hair_follicle1.20294915
65MP0000026_abnormal_inner_ear1.19751632
66MP0008872_abnormal_physiological_respon1.18872421
67MP0002733_abnormal_thermal_nociception1.17020101
68MP0004885_abnormal_endolymph1.15462618
69MP0001963_abnormal_hearing_physiology1.14909639
70MP0002066_abnormal_motor_capabilities/c1.14142040
71MP0005379_endocrine/exocrine_gland_phen1.12403755
72MP0002160_abnormal_reproductive_system1.11722319
73MP0000955_abnormal_spinal_cord1.10976743
74MP0008569_lethality_at_weaning1.10442887
75MP0002277_abnormal_respiratory_mucosa1.09318539
76MP0002909_abnormal_adrenal_gland1.06349525
77MP0005499_abnormal_olfactory_system1.02586029
78MP0005394_taste/olfaction_phenotype1.02586029
79MP0009780_abnormal_chondrocyte_physiolo1.01860460
80MP0001346_abnormal_lacrimal_gland1.01290846
81MP0003698_abnormal_male_reproductive1.00386190
82MP0003941_abnormal_skin_development0.99851622
83MP0000372_irregular_coat_pigmentation0.99825819
84MP0002152_abnormal_brain_morphology0.98333235
85MP0005187_abnormal_penis_morphology0.96660408
86MP0003634_abnormal_glial_cell0.95542912
87MP0008260_abnormal_autophagy0.93553825
88MP0003137_abnormal_impulse_conducting0.93053115
89MP0005084_abnormal_gallbladder_morpholo0.91212307
90MP0003879_abnormal_hair_cell0.86802931
91MP0004215_abnormal_myocardial_fiber0.86565879
92MP0001929_abnormal_gametogenesis0.86226082
93MP0004147_increased_porphyrin_level0.85790896
94MP0002938_white_spotting0.85678058
95MP0004811_abnormal_neuron_physiology0.85176823
96MP0000015_abnormal_ear_pigmentation0.85097523
97MP0005195_abnormal_posterior_eye0.85058076
98MP0008789_abnormal_olfactory_epithelium0.84246096
99MP0000427_abnormal_hair_cycle0.83432164
100MP0001177_atelectasis0.83217831
101MP0003938_abnormal_ear_development0.82819041
102MP0002928_abnormal_bile_duct0.81590265
103MP0003011_delayed_dark_adaptation0.81431722
104MP0003718_maternal_effect0.80938459
105MP0003950_abnormal_plasma_membrane0.80526699
106MP0005389_reproductive_system_phenotype0.80190939
107MP0004145_abnormal_muscle_electrophysio0.79879413
108MP0004043_abnormal_pH_regulation0.79872638
109MP0002234_abnormal_pharynx_morphology0.78487791
110MP0002876_abnormal_thyroid_physiology0.78294375
111MP0000516_abnormal_urinary_system0.77664159
112MP0002837_dystrophic_cardiac_calcinosis0.75161730
113MP0003121_genomic_imprinting0.74954596
114MP0003631_nervous_system_phenotype0.74753316
115MP0003122_maternal_imprinting0.74707620
116MP0003633_abnormal_nervous_system0.74307398
117MP0004133_heterotaxia0.72365390
118MP0001664_abnormal_digestion0.70184906
119MP0004085_abnormal_heartbeat0.65407064
120MP0000647_abnormal_sebaceous_gland0.64352064
121MP0000049_abnormal_middle_ear0.64059771
122MP0008995_early_reproductive_senescence0.62102145
123MP0002177_abnormal_outer_ear0.61308088

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)5.19348075
2Dynein arm defect of respiratory motile cilia (HP:0012255)4.97435657
3Absent/shortened dynein arms (HP:0200106)4.97435657
4Abnormal ciliary motility (HP:0012262)4.62902049
5Abnormal respiratory motile cilium physiology (HP:0012261)4.58319931
6Abnormal respiratory epithelium morphology (HP:0012253)4.05895911
7Abnormal respiratory motile cilium morphology (HP:0005938)4.05895911
8Focal motor seizures (HP:0011153)3.77639023
9Febrile seizures (HP:0002373)3.37942314
10Medial flaring of the eyebrow (HP:0010747)3.17554013
11Epileptic encephalopathy (HP:0200134)3.16483088
12Rhinitis (HP:0012384)3.03603189
13Gait imbalance (HP:0002141)2.94771513
14Type II lissencephaly (HP:0007260)2.88617634
15Chronic hepatic failure (HP:0100626)2.84759230
16Nephrogenic diabetes insipidus (HP:0009806)2.83839303
17Abnormality of the renal cortex (HP:0011035)2.82458065
18Congenital primary aphakia (HP:0007707)2.73793530
19Atonic seizures (HP:0010819)2.72286343
20Congenital stationary night blindness (HP:0007642)2.70694425
21Septo-optic dysplasia (HP:0100842)2.70575419
22True hermaphroditism (HP:0010459)2.70259977
23Pancreatic fibrosis (HP:0100732)2.67681757
24Limb dystonia (HP:0002451)2.66690891
25Absent septum pellucidum (HP:0001331)2.56724138
26Acute necrotizing encephalopathy (HP:0006965)2.53146209
27Vaginal atresia (HP:0000148)2.50933115
28Genital tract atresia (HP:0001827)2.48925234
29Increased CSF lactate (HP:0002490)2.45608566
30Decreased central vision (HP:0007663)2.44383133
31Progressive cerebellar ataxia (HP:0002073)2.41538781
32Cystic liver disease (HP:0006706)2.40934758
33Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.36863948
34Degeneration of the lateral corticospinal tracts (HP:0002314)2.36863948
35Abnormality of the septum pellucidum (HP:0007375)2.36504881
36Nephronophthisis (HP:0000090)2.36160651
37Abnormal drinking behavior (HP:0030082)2.35728135
38Polydipsia (HP:0001959)2.35728135
39Sclerocornea (HP:0000647)2.35208880
40Tubular atrophy (HP:0000092)2.32827220
41Abolished electroretinogram (ERG) (HP:0000550)2.32354909
42Lipid accumulation in hepatocytes (HP:0006561)2.28443285
43Focal seizures (HP:0007359)2.27358095
44Pendular nystagmus (HP:0012043)2.24991259
45Pachygyria (HP:0001302)2.22748301
46Hepatocellular necrosis (HP:0001404)2.20219412
47Atelectasis (HP:0100750)2.20157337
48Pancreatic cysts (HP:0001737)2.20150298
49Optic nerve hypoplasia (HP:0000609)2.18258413
50Progressive macrocephaly (HP:0004481)2.17111113
51Stomach cancer (HP:0012126)2.15185924
52Optic disc pallor (HP:0000543)2.14955688
53Hepatic necrosis (HP:0002605)2.14618685
54Abnormality of macular pigmentation (HP:0008002)2.12238584
55Hypothermia (HP:0002045)2.09988258
56Abnormal mitochondria in muscle tissue (HP:0008316)2.09761214
57Abnormal hair whorl (HP:0010721)2.07194922
58Broad-based gait (HP:0002136)2.06981432
59Abnormal rod and cone electroretinograms (HP:0008323)2.06397827
60Molar tooth sign on MRI (HP:0002419)2.04506387
61Abnormality of midbrain morphology (HP:0002418)2.04506387
62Congenital sensorineural hearing impairment (HP:0008527)2.03799476
63Mitochondrial inheritance (HP:0001427)2.03247953
64Postaxial foot polydactyly (HP:0001830)2.02979303
65Attenuation of retinal blood vessels (HP:0007843)2.02147747
66Poor coordination (HP:0002370)2.00217705
67Tubulointerstitial nephritis (HP:0001970)1.99875887
68Congenital hepatic fibrosis (HP:0002612)1.99511188
69Aplasia/Hypoplasia of the lens (HP:0008063)1.99177097
70Absent rod-and cone-mediated responses on ERG (HP:0007688)1.98981839
71Postaxial hand polydactyly (HP:0001162)1.98387449
72Polyuria (HP:0000103)1.98346617
73Occipital encephalocele (HP:0002085)1.97941251
74Fetal akinesia sequence (HP:0001989)1.96977105
75Aplasia/Hypoplasia of the tongue (HP:0010295)1.96897150
76Bony spicule pigmentary retinopathy (HP:0007737)1.96310086
77Parakeratosis (HP:0001036)1.95713111
78Tubulointerstitial abnormality (HP:0001969)1.95352073
79Myokymia (HP:0002411)1.94230142
80Adrenal hypoplasia (HP:0000835)1.93992446
81Methylmalonic acidemia (HP:0002912)1.92565814
82Anencephaly (HP:0002323)1.92381458
83Abnormality of the renal medulla (HP:0100957)1.91783823
84Retinal dysplasia (HP:0007973)1.89452174
85Split foot (HP:0001839)1.89397528
86Renal cortical cysts (HP:0000803)1.88870884
87Dialeptic seizures (HP:0011146)1.88592291
88Male pseudohermaphroditism (HP:0000037)1.86813065
89Abnormality of the corticospinal tract (HP:0002492)1.84675232
90Renal Fanconi syndrome (HP:0001994)1.84642524
91Generalized tonic-clonic seizures (HP:0002069)1.84619765
92Absence seizures (HP:0002121)1.83943878
93Aplasia/Hypoplasia of the tibia (HP:0005772)1.82824882
94Preaxial hand polydactyly (HP:0001177)1.81577450
95Chronic bronchitis (HP:0004469)1.80440620
96Glycosuria (HP:0003076)1.80234441
97Abnormality of urine glucose concentration (HP:0011016)1.80234441
98Myelomeningocele (HP:0002475)1.79971817
99Epileptiform EEG discharges (HP:0011182)1.78774361
100Bell-shaped thorax (HP:0001591)1.78567014
101EEG with generalized epileptiform discharges (HP:0011198)1.77771472
102Hypsarrhythmia (HP:0002521)1.76717159
103Blue irides (HP:0000635)1.76524548
104Agitation (HP:0000713)1.76178885
105Increased hepatocellular lipid droplets (HP:0006565)1.75921814
106Inability to walk (HP:0002540)1.75148522
107Decreased activity of mitochondrial respiratory chain (HP:0008972)1.74828846
108Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.74828846
109Duplicated collecting system (HP:0000081)1.74454840
110Hyperventilation (HP:0002883)1.74280891
111Retinitis pigmentosa (HP:0000510)1.73160113
112Keratoconus (HP:0000563)1.72655184
113Increased corneal curvature (HP:0100692)1.72655184
114Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.72306462
115Absent eyebrow (HP:0002223)1.71996628
116Abnormality of renal resorption (HP:0011038)1.70542695
1173-Methylglutaconic aciduria (HP:0003535)1.70480272
118Dyschromatopsia (HP:0007641)1.68469235
119Drooling (HP:0002307)1.67626852
120Excessive salivation (HP:0003781)1.67626852
121Aganglionic megacolon (HP:0002251)1.67611141
122Acute encephalopathy (HP:0006846)1.66944632
123Lissencephaly (HP:0001339)1.66931426
124Absent speech (HP:0001344)1.66457351
125Gaze-evoked nystagmus (HP:0000640)1.65663858
126Polyphagia (HP:0002591)1.64469458
127Specific learning disability (HP:0001328)1.63972576
128Aplasia involving bones of the extremities (HP:0009825)1.63664466
129Aplasia involving bones of the upper limbs (HP:0009823)1.63664466
130Aplasia of the phalanges of the hand (HP:0009802)1.63664466
131Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.63630134
132Cupped ear (HP:0000378)1.63331092
133Central scotoma (HP:0000603)1.63253363
134Abnormality of incisor morphology (HP:0011063)1.62892770
135Hemiparesis (HP:0001269)1.61833805
136Abnormality of the axillary hair (HP:0100134)1.60701922

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK3.69673895
2FRK3.41883544
3TNIK3.35782240
4EPHA42.74794649
5NTRK32.67396499
6MARK12.60218609
7STK392.32982205
8PNCK2.30409623
9MAP2K72.27530375
10MAPK132.27260648
11NTRK21.91397784
12MAP4K21.82293890
13TLK11.78976742
14PKN11.75346569
15GRK71.73247639
16PINK11.68002575
17NUAK11.65656074
18BMPR1B1.64848900
19OXSR11.64715814
20MUSK1.60060486
21BMPR21.59663996
22MAP3K121.58094328
23ICK1.57193372
24PBK1.48291015
25AKT31.47725816
26TAOK31.41188645
27BCR1.40669599
28PLK21.39170543
29MKNK21.37189412
30IRAK21.32005878
31WNK41.31707026
32ZAK1.31694651
33PHKG11.30938975
34PHKG21.30938975
35CDK31.29380838
36SGK2231.24837908
37SGK4941.24837908
38MST41.18897128
39CDK191.18622728
40YES11.18532120
41BCKDK1.17255721
42NEK61.16416987
43CSNK1G31.16361661
44MAP3K41.14774827
45IRAK11.13989403
46MAPKAPK51.13744236
47DYRK21.13534721
48PRPF4B1.11797335
49ACVR1B1.09230272
50OBSCN1.08535746
51CAMK2A1.06144090
52GRK11.05898637
53ADRBK21.03716257
54STK161.03267885
55CSNK1A1L1.02855928
56SGK21.02783297
57CAMK2B1.01258581
58PLK40.99773603
59TRIM280.99541074
60CSNK1G20.99526154
61SIK20.98110442
62VRK10.95322318
63WNK10.91827230
64BRD40.91265537
65NME10.90943627
66PRKCE0.90532151
67MINK10.90262475
68UHMK10.89837902
69WNK30.88797038
70DYRK1A0.88642557
71TGFBR10.86607701
72MKNK10.86575363
73CAMK2D0.86212493
74INSRR0.85092414
75MAPK150.84133516
76PDK30.83812199
77PDK40.83812199
78FGFR20.82918413
79CDK50.82002487
80SRPK10.79315566
81MAP2K40.78494600
82RIPK40.78431160
83CSNK1G10.76958825
84PRKCG0.74392601
85CDK80.69255650
86GRK50.67825680
87CAMKK20.65205626
88TNK20.64503133
89MAP2K60.62879387
90BRAF0.62008926
91STK240.61448506
92DYRK30.59084943
93STK38L0.57005202
94TIE10.56965885
95DAPK20.55484824
96CCNB10.54980000
97LATS10.54550997
98IRAK30.53910515
99ABL20.53879872
100ADRBK10.53039338
101PDK20.52050413
102PRKACA0.51344185
103CAMK2G0.51098819
104PRKG10.50711763
105CAMK10.50559692
106SGK10.50087488
107EIF2AK20.49206058
108MAP3K90.48168590
109PAK30.47474670
110RPS6KA50.47423463
111STK110.45710644
112LIMK10.44993354
113PRKCQ0.43390099
114PLK30.42695959
115ROCK20.41728423
116TXK0.41038807
117PTK2B0.40939213
118STK380.40339298
119PRKACB0.39663389
120PAK60.38867641
121CSNK1E0.38672929
122CSNK1D0.37788852
123IRAK40.37577612
124PRKAA10.37374408
125CSNK1A10.37071782
126PRKCA0.36118936
127MAPK70.34155363
128ARAF0.33851633
129MARK20.32919764
130BLK0.32801870
131ERBB30.31497275

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.34832251
2Phototransduction_Homo sapiens_hsa047443.11791031
3Oxidative phosphorylation_Homo sapiens_hsa001902.85326357
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.47043863
5Butanoate metabolism_Homo sapiens_hsa006502.42591092
6Glutamatergic synapse_Homo sapiens_hsa047242.36842791
7Morphine addiction_Homo sapiens_hsa050322.30292329
8GABAergic synapse_Homo sapiens_hsa047272.21172278
9Taste transduction_Homo sapiens_hsa047422.20791592
10Parkinsons disease_Homo sapiens_hsa050122.20344736
11Circadian entrainment_Homo sapiens_hsa047132.14567851
12Serotonergic synapse_Homo sapiens_hsa047262.09982379
13Olfactory transduction_Homo sapiens_hsa047402.09266786
14Synaptic vesicle cycle_Homo sapiens_hsa047212.08952455
15Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.03512356
16Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.00862902
17Alzheimers disease_Homo sapiens_hsa050102.00052308
18Cardiac muscle contraction_Homo sapiens_hsa042601.96936290
19Huntingtons disease_Homo sapiens_hsa050161.93587489
20Amphetamine addiction_Homo sapiens_hsa050311.91057937
21Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.85981414
22Protein export_Homo sapiens_hsa030601.78616464
23Nitrogen metabolism_Homo sapiens_hsa009101.72669349
24Collecting duct acid secretion_Homo sapiens_hsa049661.70454602
25Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.59163830
26Insulin secretion_Homo sapiens_hsa049111.56026454
27SNARE interactions in vesicular transport_Homo sapiens_hsa041301.51282104
28Ether lipid metabolism_Homo sapiens_hsa005651.49920380
29Salivary secretion_Homo sapiens_hsa049701.49745712
30Calcium signaling pathway_Homo sapiens_hsa040201.49148727
31Cocaine addiction_Homo sapiens_hsa050301.40383816
32Long-term potentiation_Homo sapiens_hsa047201.38432176
33Dopaminergic synapse_Homo sapiens_hsa047281.37338063
34Maturity onset diabetes of the young_Homo sapiens_hsa049501.35060376
35Sphingolipid metabolism_Homo sapiens_hsa006001.35012645
36Tryptophan metabolism_Homo sapiens_hsa003801.30447985
37Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.25722801
38Axon guidance_Homo sapiens_hsa043601.25509735
39Long-term depression_Homo sapiens_hsa047301.24255389
40Fatty acid elongation_Homo sapiens_hsa000621.24208100
41Cholinergic synapse_Homo sapiens_hsa047251.23429689
42Propanoate metabolism_Homo sapiens_hsa006401.19692303
43Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.14795442
44Gastric acid secretion_Homo sapiens_hsa049711.12787992
45Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.12593857
46Renin secretion_Homo sapiens_hsa049241.06669837
47Arachidonic acid metabolism_Homo sapiens_hsa005901.03343013
48Peroxisome_Homo sapiens_hsa041461.02287499
49RNA polymerase_Homo sapiens_hsa030201.00780520
50Fanconi anemia pathway_Homo sapiens_hsa034600.98847385
51Basal transcription factors_Homo sapiens_hsa030220.97012843
52Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.95972784
53Selenocompound metabolism_Homo sapiens_hsa004500.95704824
54Primary bile acid biosynthesis_Homo sapiens_hsa001200.94186449
55Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.94087658
56Steroid hormone biosynthesis_Homo sapiens_hsa001400.93422238
57Autoimmune thyroid disease_Homo sapiens_hsa053200.92778213
58Caffeine metabolism_Homo sapiens_hsa002320.91133302
59RNA degradation_Homo sapiens_hsa030180.90183758
60Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.89885156
61Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.88773474
62Vitamin B6 metabolism_Homo sapiens_hsa007500.88737354
63Chemical carcinogenesis_Homo sapiens_hsa052040.88587009
64Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.88464934
65beta-Alanine metabolism_Homo sapiens_hsa004100.87849747
66Vibrio cholerae infection_Homo sapiens_hsa051100.86803945
67cAMP signaling pathway_Homo sapiens_hsa040240.86257469
68Rheumatoid arthritis_Homo sapiens_hsa053230.85902093
69Oxytocin signaling pathway_Homo sapiens_hsa049210.85848615
70Linoleic acid metabolism_Homo sapiens_hsa005910.82949688
71Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.82218850
72Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.80108692
73Dorso-ventral axis formation_Homo sapiens_hsa043200.79611914
74Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.77645034
75Alcoholism_Homo sapiens_hsa050340.76566950
76alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.75948173
77Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.73416777
78Steroid biosynthesis_Homo sapiens_hsa001000.72388164
79Sulfur metabolism_Homo sapiens_hsa009200.72306189
80Homologous recombination_Homo sapiens_hsa034400.71926797
81Aldosterone synthesis and secretion_Homo sapiens_hsa049250.69975354
82Gap junction_Homo sapiens_hsa045400.69624984
83Type I diabetes mellitus_Homo sapiens_hsa049400.69412411
84Vascular smooth muscle contraction_Homo sapiens_hsa042700.68912968
85Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.68477836
86Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.68193186
87Circadian rhythm_Homo sapiens_hsa047100.68183787
88Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.67063156
89Ribosome_Homo sapiens_hsa030100.66805295
90Regulation of autophagy_Homo sapiens_hsa041400.65579656
91GnRH signaling pathway_Homo sapiens_hsa049120.64416023
92Purine metabolism_Homo sapiens_hsa002300.63732941
93ErbB signaling pathway_Homo sapiens_hsa040120.63593724
94Glycerophospholipid metabolism_Homo sapiens_hsa005640.62165361
95Retinol metabolism_Homo sapiens_hsa008300.61988175
96Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.61232947
97Phosphatidylinositol signaling system_Homo sapiens_hsa040700.59212936
98Ras signaling pathway_Homo sapiens_hsa040140.56787265
99Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.55962048
100Allograft rejection_Homo sapiens_hsa053300.55409240
101Dilated cardiomyopathy_Homo sapiens_hsa054140.55326190
102Pentose and glucuronate interconversions_Homo sapiens_hsa000400.54904072
103Wnt signaling pathway_Homo sapiens_hsa043100.52461991
104Graft-versus-host disease_Homo sapiens_hsa053320.52371676
105ABC transporters_Homo sapiens_hsa020100.52365740
106Choline metabolism in cancer_Homo sapiens_hsa052310.52188862
107Pancreatic secretion_Homo sapiens_hsa049720.52005324
108Ovarian steroidogenesis_Homo sapiens_hsa049130.51712558
109cGMP-PKG signaling pathway_Homo sapiens_hsa040220.51574385
110Proteasome_Homo sapiens_hsa030500.51570012
111Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.50246245
112MAPK signaling pathway_Homo sapiens_hsa040100.48215965
113Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.47806378
114Fatty acid degradation_Homo sapiens_hsa000710.46484984
115Sulfur relay system_Homo sapiens_hsa041220.46419931
116Melanogenesis_Homo sapiens_hsa049160.41888124
117Phospholipase D signaling pathway_Homo sapiens_hsa040720.41330421
118Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.39896923
119Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.39599076
120Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.39184162
121Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.38740683
122Arginine and proline metabolism_Homo sapiens_hsa003300.37948518
123Hedgehog signaling pathway_Homo sapiens_hsa043400.37623774
124Oocyte meiosis_Homo sapiens_hsa041140.36389229
125Histidine metabolism_Homo sapiens_hsa003400.35342057
126Nucleotide excision repair_Homo sapiens_hsa034200.34344451
127Inositol phosphate metabolism_Homo sapiens_hsa005620.32635499
128Mineral absorption_Homo sapiens_hsa049780.31050885
129Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.30899143
130Metabolic pathways_Homo sapiens_hsa011000.30844479
131Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.29500996
132Phagosome_Homo sapiens_hsa041450.28669495
133Estrogen signaling pathway_Homo sapiens_hsa049150.28456541
134Sphingolipid signaling pathway_Homo sapiens_hsa040710.23591150
135Basal cell carcinoma_Homo sapiens_hsa052170.21873320
136Asthma_Homo sapiens_hsa053100.21869814

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