FAM160A1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sarcomere organization (GO:0045214)6.73544776
2establishment of skin barrier (GO:0061436)6.15396514
3keratinization (GO:0031424)6.06401974
4negative regulation of potassium ion transmembrane transporter activity (GO:1901017)6.03347416
5regulation of water loss via skin (GO:0033561)5.82148217
6cardiac myofibril assembly (GO:0055003)5.71038732
7muscle filament sliding (GO:0030049)5.67271014
8actin-myosin filament sliding (GO:0033275)5.67271014
9myofibril assembly (GO:0030239)5.46475171
10regulation of skeletal muscle contraction (GO:0014819)5.42437224
11actin-mediated cell contraction (GO:0070252)5.29024796
12bundle of His cell to Purkinje myocyte communication (GO:0086069)5.26127747
13negative regulation of potassium ion transmembrane transport (GO:1901380)5.15140168
14carnitine shuttle (GO:0006853)5.14532676
15plasma membrane repair (GO:0001778)5.07234199
16ventricular cardiac muscle cell action potential (GO:0086005)4.89479148
17cardiac muscle cell development (GO:0055013)4.87183643
18positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)4.77516169
19cardiac cell development (GO:0055006)4.65666707
20regulation of cardioblast differentiation (GO:0051890)4.56842565
21fatty acid transmembrane transport (GO:1902001)4.44485243
22actomyosin structure organization (GO:0031032)4.36197749
23nuclear pore complex assembly (GO:0051292)4.26026156
24regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)4.25385899
25desmosome organization (GO:0002934)4.21993040
26actin filament-based movement (GO:0030048)4.18302955
27cardiac muscle contraction (GO:0060048)4.06650734
28regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)4.03759791
29response to muscle activity (GO:0014850)3.98296010
30sarcoplasmic reticulum calcium ion transport (GO:0070296)3.94600983
31skeletal muscle adaptation (GO:0043501)3.90390389
32striated muscle contraction (GO:0006941)3.86447064
33carnitine transmembrane transport (GO:1902603)3.84548235
34tricarboxylic acid cycle (GO:0006099)3.82235271
35negative regulation of hormone biosynthetic process (GO:0032353)3.81416553
36negative regulation of hormone metabolic process (GO:0032351)3.81416553
37regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.79413887
38multicellular organismal water homeostasis (GO:0050891)3.76630377
39regulation of acyl-CoA biosynthetic process (GO:0050812)3.75197823
40keratinocyte differentiation (GO:0030216)3.74581482
41nuclear pore organization (GO:0006999)3.73913057
42keratinocyte proliferation (GO:0043616)3.67629119
43amino-acid betaine transport (GO:0015838)3.65247264
44carnitine transport (GO:0015879)3.65247264
45regulation of relaxation of muscle (GO:1901077)3.62370772
46gap junction assembly (GO:0016264)3.59093700
47negative regulation of keratinocyte proliferation (GO:0010839)3.58024229
48regulation of transforming growth factor beta2 production (GO:0032909)3.57619883
49regulation of sequestering of triglyceride (GO:0010889)3.55046803
50regulation of glucocorticoid metabolic process (GO:0031943)3.46501516
51paraxial mesoderm development (GO:0048339)3.45495031
52cardiac muscle tissue morphogenesis (GO:0055008)3.44748353
53glycogen catabolic process (GO:0005980)3.43522931
54regulation of female gonad development (GO:2000194)3.43011510
55skeletal muscle contraction (GO:0003009)3.42827916
56regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.39180688
57regulation of actin filament-based movement (GO:1903115)3.36415189
58regulation of gene silencing by miRNA (GO:0060964)3.34853118
59regulation of gene silencing by RNA (GO:0060966)3.34853118
60regulation of posttranscriptional gene silencing (GO:0060147)3.34853118
61protein complex localization (GO:0031503)3.33677196
62IMP metabolic process (GO:0046040)3.32312980
63hemidesmosome assembly (GO:0031581)3.29828515
64regulation of cofactor metabolic process (GO:0051193)3.29826046
65regulation of coenzyme metabolic process (GO:0051196)3.29826046
66heart trabecula formation (GO:0060347)3.29051726
67positive regulation of sodium ion transmembrane transporter activity (GO:2000651)3.26021616
68skeletal muscle fiber development (GO:0048741)3.25620601
69fibroblast migration (GO:0010761)3.24252118
70striated muscle atrophy (GO:0014891)3.23494894
71regulation of membrane repolarization (GO:0060306)3.23344309
72pre-miRNA processing (GO:0031054)3.22922323
73hippo signaling (GO:0035329)3.20228956
74mitotic sister chromatid cohesion (GO:0007064)3.19953628
75ventricular cardiac muscle cell development (GO:0055015)3.19564889
76glucan catabolic process (GO:0009251)3.18678851
77regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.18098008
78muscle tissue morphogenesis (GO:0060415)3.16252581
79cardiac muscle hypertrophy (GO:0003300)3.16195032
80regulation of Wnt signaling pathway involved in heart development (GO:0003307)3.15805074
81regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.15673582
82ventricular cardiac muscle tissue morphogenesis (GO:0055010)3.15239308
83piRNA metabolic process (GO:0034587)3.11949420
84DNA damage induced protein phosphorylation (GO:0006975)3.11772305
85water homeostasis (GO:0030104)3.11080876
86striated muscle cell development (GO:0055002)3.10194659
87response to stimulus involved in regulation of muscle adaptation (GO:0014874)3.09868103
88chemical homeostasis within a tissue (GO:0048875)3.09464610
89cell communication involved in cardiac conduction (GO:0086065)3.09349535
90epidermal cell differentiation (GO:0009913)3.08803212
91polarized epithelial cell differentiation (GO:0030859)3.08521868
92striated muscle hypertrophy (GO:0014897)3.08004721
93negative regulation of smooth muscle cell differentiation (GO:0051151)3.07201636
94cardiac muscle cell action potential (GO:0086001)3.04206702
95cardiac muscle cell action potential involved in contraction (GO:0086002)3.03121890
96cellular polysaccharide catabolic process (GO:0044247)3.01554220
97regulation of cell communication by electrical coupling (GO:0010649)2.99713054
98NLS-bearing protein import into nucleus (GO:0006607)2.98942592
99response to inactivity (GO:0014854)2.97422463
100cellular protein complex localization (GO:0034629)2.96636465
101notochord development (GO:0030903)2.94215050
102myotube cell development (GO:0014904)2.93807196
103creatine metabolic process (GO:0006600)2.90605247
104pore complex assembly (GO:0046931)2.90459138
105intracellular lipid transport (GO:0032365)2.90441364
106regulation of sulfur metabolic process (GO:0042762)2.89848725
107glucan biosynthetic process (GO:0009250)2.89342961
108glycogen biosynthetic process (GO:0005978)2.89342961
109regulation of meiosis (GO:0040020)2.89316844
110regulation of tight junction assembly (GO:2000810)2.87807051
111negative regulation of retinoic acid receptor signaling pathway (GO:0048387)2.87036941
112regulation of meiosis I (GO:0060631)2.85891279
113muscle contraction (GO:0006936)2.85860454
114heart process (GO:0003015)2.84200827
115heart contraction (GO:0060047)2.84200827
116regulation of striated muscle contraction (GO:0006942)2.83098545
1172-oxoglutarate metabolic process (GO:0006103)2.82542192
118lysine metabolic process (GO:0006553)2.81850073
119lysine catabolic process (GO:0006554)2.81850073
120adult heart development (GO:0007512)2.80909942
121type B pancreatic cell development (GO:0003323)2.80585842
122regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.79585739
123regulation of p38MAPK cascade (GO:1900744)2.77367540
124regulation of keratinocyte proliferation (GO:0010837)2.76668526
125striated muscle adaptation (GO:0014888)2.76409836
126anterior/posterior axis specification, embryo (GO:0008595)2.76031806
127skeletal muscle tissue regeneration (GO:0043403)2.75299148
128positive regulation of sodium ion transmembrane transport (GO:1902307)2.74687430
129cytoplasmic microtubule organization (GO:0031122)2.73347695
130cell-substrate junction assembly (GO:0007044)2.72838057
131epithelial cell-cell adhesion (GO:0090136)2.70630104
132NADH metabolic process (GO:0006734)2.67940529
133regulation of steroid hormone biosynthetic process (GO:0090030)2.66964016
134positive regulation of catenin import into nucleus (GO:0035413)2.66694474
135myotube differentiation (GO:0014902)2.66538431
136positive regulation of pathway-restricted SMAD protein phosphorylation (GO:0010862)2.66384369
137peptidyl-lysine dimethylation (GO:0018027)2.65483703
138polysaccharide catabolic process (GO:0000272)2.65101386
139epidermis development (GO:0008544)2.64119736
140IMP biosynthetic process (GO:0006188)2.64109372
141muscle fiber development (GO:0048747)2.62812018
142ribosome assembly (GO:0042255)2.62724511
143muscle system process (GO:0003012)2.61537076
144positive regulation of heart contraction (GO:0045823)2.61412692
145muscle cell development (GO:0055001)2.60267486
146intestinal epithelial cell development (GO:0060576)2.58623261
147muscle hypertrophy (GO:0014896)2.56499867
148genitalia morphogenesis (GO:0035112)2.55733143
149regulation of fatty acid oxidation (GO:0046320)2.55649604
150muscle atrophy (GO:0014889)2.54425184
151regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.54321892
152tight junction assembly (GO:0070830)2.49866754
153cell-substrate adherens junction assembly (GO:0007045)2.46966972
154focal adhesion assembly (GO:0048041)2.46966972
155myoblast fusion (GO:0007520)2.46774918
156mitotic chromosome condensation (GO:0007076)2.43484884
157glycogen metabolic process (GO:0005977)2.41540625

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.26697595
2SMAD4_19686287_ChIP-ChIP_HaCaT_Human3.87223464
3ESR1_20079471_ChIP-ChIP_T-47D_Human3.40638072
4EP300_21415370_ChIP-Seq_HL-1_Mouse3.33931707
5TP63_17297297_ChIP-ChIP_HaCaT_Human3.27332023
6PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.64946532
7TBX20_22080862_ChIP-Seq_HEART_Mouse2.49007831
8TBX20_22328084_ChIP-Seq_HEART_Mouse2.49007831
9TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.45290883
10ESR2_21235772_ChIP-Seq_MCF-7_Human2.44524147
11KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.39323020
12ESR1_21235772_ChIP-Seq_MCF-7_Human2.23588122
13TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.16210675
14SMAD_19615063_ChIP-ChIP_OVARY_Human2.08449085
15FOXM1_23109430_ChIP-Seq_U2OS_Human2.05041561
16RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.97837298
17MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.84631179
18ZNF263_19887448_ChIP-Seq_K562_Human1.83328050
19PPAR_26484153_Chip-Seq_NCI-H1993_Human1.82698011
20KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.81739631
21KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.81739631
22KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.81739631
23RARG_19884340_ChIP-ChIP_MEFs_Mouse1.76715282
24* CJUN_26792858_Chip-Seq_BT549_Human1.72250631
25NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.70903821
26FOXO3_23340844_ChIP-Seq_DLD1_Human1.69132227
27CDX2_19796622_ChIP-Seq_MESCs_Mouse1.66023139
28NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.61478024
29ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.61467098
30* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.60847807
31LXR_22158963_ChIP-Seq_LIVER_Mouse1.59665565
32ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.59297135
33SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.58170520
34SOX9_24532713_ChIP-Seq_HFSC_Mouse1.55529839
35ATF3_27146783_Chip-Seq_COLON_Human1.53431296
36PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.49919147
37NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.47835531
38TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.46454193
39TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.45609512
40RUNX1_27514584_Chip-Seq_MCF-7_Human1.45408181
41RXR_22158963_ChIP-Seq_LIVER_Mouse1.44974067
42STAT6_21828071_ChIP-Seq_BEAS2B_Human1.41834435
43NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.41477648
44ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.41266455
45KAP1_22055183_ChIP-Seq_ESCs_Mouse1.40812460
46TCF3_18692474_ChIP-Seq_MESCs_Mouse1.40514579
47PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.40107724
48CHD1_26751641_Chip-Seq_LNCaP_Human1.39937806
49AR_21572438_ChIP-Seq_LNCaP_Human1.39208794
50KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.38693230
51PPARA_22158963_ChIP-Seq_LIVER_Mouse1.36032768
52CLOCK_20551151_ChIP-Seq_293T_Human1.33863615
53SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.32013995
54NANOG_16153702_ChIP-ChIP_HESCs_Human1.31872345
55ISL1_27105846_Chip-Seq_CPCs_Mouse1.31061756
56TCF3_18692474_ChIP-Seq_MEFs_Mouse1.30051710
57PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.29942589
58HIF1A_21447827_ChIP-Seq_MCF-7_Human1.29035081
59KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.28356239
60FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.28264598
61PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.27308364
62FOXA2_19822575_ChIP-Seq_HepG2_Human1.27053578
63E2F1_21310950_ChIP-Seq_MCF-7_Human1.26589116
64ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.26440966
65STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.25983582
66POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.24980395
67E2F4_17652178_ChIP-ChIP_JURKAT_Human1.24405774
68TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.23272407
69ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.22500591
70CDX2_22108803_ChIP-Seq_LS180_Human1.20633460
71FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.19779988
72ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.18592734
73EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.18364837
74FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.17306966
75* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.16771811
76GATA3_24758297_ChIP-Seq_MCF-7_Human1.14520633
77TCF4_18268006_ChIP-ChIP_LS174T_Human1.13458213
78NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.12767182
79* TP63_23658742_ChIP-Seq_EP156T_Human1.11862572
80SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.11633036
81GATA4_21415370_ChIP-Seq_HL-1_Mouse1.09032649
82GATA6_25053715_ChIP-Seq_YYC3_Human1.08073966
83SMAD3_21741376_ChIP-Seq_HESCs_Human1.07826547
84GATA2_21666600_ChIP-Seq_HMVEC_Human1.06121073
85AHR_22903824_ChIP-Seq_MCF-7_Human1.05718613
86AR_21909140_ChIP-Seq_LNCAP_Human1.05664901
87TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.04296980
88* TP63_22573176_ChIP-Seq_HFKS_Human1.04047175
89AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.03331814
90PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.00144614
91CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.99751004
92CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.99680721
93FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.99608730
94GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99218242
95AUTS2_25519132_ChIP-Seq_293T-REX_Human0.99214593
96JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.98533342
97MYC_18555785_ChIP-Seq_MESCs_Mouse0.98388661
98PADI4_21655091_ChIP-ChIP_MCF-7_Human0.96879758
99PIAS1_25552417_ChIP-Seq_VCAP_Human0.96608064
100TP53_16413492_ChIP-PET_HCT116_Human0.96418497
101FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.96386677
102FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.96290072
103GATA4_25053715_ChIP-Seq_YYC3_Human0.96137309
104HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.95892440
105NANOG_18692474_ChIP-Seq_MESCs_Mouse0.95002097
106SOX2_27498859_Chip-Seq_STOMACH_Mouse0.94701039
107EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.94496067
108RACK7_27058665_Chip-Seq_MCF-7_Human0.93835404
109CTNNB1_20460455_ChIP-Seq_HCT116_Human0.93460947
110NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.93304761
111MYC_19079543_ChIP-ChIP_MESCs_Mouse0.93257066
112MYCN_18555785_ChIP-Seq_MESCs_Mouse0.92637898
113CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.92236589
114SALL4_18804426_ChIP-ChIP_XEN_Mouse0.92166161
115P63_26484246_Chip-Seq_KERATINOCYTES_Human0.91938727
116TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.91891630
117AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.91106218
118TBL1_22424771_ChIP-Seq_293T_Human0.91091109
119RUNX1_26923725_Chip-Seq_HPCs_Mouse0.90490863
120FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.90463808
121JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.89799155
122ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.89610170
123BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.89598671
124HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.89269380
125NFYA_21822215_ChIP-Seq_K562_Human0.89173619
126YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.89160423
127TBX3_20139965_ChIP-Seq_ESCs_Mouse0.89122779
128NELFA_20434984_ChIP-Seq_ESCs_Mouse0.88885006
129KLF5_25053715_ChIP-Seq_YYC3_Human0.87508766
130CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.87140978
131STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.87013952
132WT1_25993318_ChIP-Seq_PODOCYTE_Human0.85889587
133TRIM28_21343339_ChIP-Seq_HEK293_Human0.85187532
134SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.84955190
135SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.84955190
136* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.84685157
137ERG_20517297_ChIP-Seq_VCAP_Human0.84264396
138SOX2_20726797_ChIP-Seq_SW620_Human0.83151666
139BRD4_25478319_ChIP-Seq_HGPS_Human0.82417900
140SALL1_21062744_ChIP-ChIP_HESCs_Human0.82164515
141* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.81998823

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003646_muscle_fatigue6.68505914
2MP0002837_dystrophic_cardiac_calcinosis5.28769970
3MP0000751_myopathy4.12460726
4MP0004084_abnormal_cardiac_muscle3.76784717
5MP0004036_abnormal_muscle_relaxation3.35789962
6MP0000749_muscle_degeneration3.33184222
7MP0004215_abnormal_myocardial_fiber3.10767163
8MP0005451_abnormal_body_composition2.87237870
9MP0004145_abnormal_muscle_electrophysio2.84130010
10MP0004087_abnormal_muscle_fiber2.74079358
11MP0010352_gastrointestinal_tract_polyps2.68624552
12MP0000750_abnormal_muscle_regeneration2.55900965
13MP0005330_cardiomyopathy2.53484731
14MP0002106_abnormal_muscle_physiology2.37220979
15MP0004185_abnormal_adipocyte_glucose2.35677267
16MP0005620_abnormal_muscle_contractility2.35341907
17MP0002269_muscular_atrophy2.27062169
18MP0002972_abnormal_cardiac_muscle2.18806512
19MP0003705_abnormal_hypodermis_morpholog2.03648009
20MP0000579_abnormal_nail_morphology1.99387519
21MP0004130_abnormal_muscle_cell1.97112636
22MP0003950_abnormal_plasma_membrane1.91699243
23MP0004484_altered_response_of1.91084410
24MP0000759_abnormal_skeletal_muscle1.88976356
25MP0010630_abnormal_cardiac_muscle1.88000146
26MP0005369_muscle_phenotype1.86206273
27MP0008775_abnormal_heart_ventricle1.79652893
28MP0008057_abnormal_DNA_replication1.74772829
29MP0004233_abnormal_muscle_weight1.70698828
30MP0005666_abnormal_adipose_tissue1.70089965
31MP0000747_muscle_weakness1.69538096
32MP0005275_abnormal_skin_tensile1.67237375
33MP0010234_abnormal_vibrissa_follicle1.67097570
34MP0009672_abnormal_birth_weight1.66905712
35MP0006138_congestive_heart_failure1.66521665
36MP0003693_abnormal_embryo_hatching1.65855545
37MP0001544_abnormal_cardiovascular_syste1.65190063
38MP0005385_cardiovascular_system_phenoty1.65190063
39MP0004957_abnormal_blastocyst_morpholog1.60658609
40MP0003890_abnormal_embryonic-extraembry1.58900931
41MP0001216_abnormal_epidermal_layer1.54493653
42MP0003137_abnormal_impulse_conducting1.51784782
43MP0003718_maternal_effect1.47600037
44MP0010368_abnormal_lymphatic_system1.44799448
45MP0000566_synostosis1.43563353
46MP0004510_myositis1.42656532
47MP0002332_abnormal_exercise_endurance1.37912419
48MP0009384_cardiac_valve_regurgitation1.35134114
49MP0002877_abnormal_melanocyte_morpholog1.34421062
50MP0000467_abnormal_esophagus_morphology1.33961239
51MP0001661_extended_life_span1.33954244
52MP0010030_abnormal_orbit_morphology1.33141560
53MP0000537_abnormal_urethra_morphology1.31967348
54MP0003221_abnormal_cardiomyocyte_apopto1.29538666
55MP0000733_abnormal_muscle_development1.26191643
56MP0002102_abnormal_ear_morphology1.24128627
57MP0003566_abnormal_cell_adhesion1.20603702
58MP0010771_integument_phenotype1.20213164
59MP0002796_impaired_skin_barrier1.15251688
60MP0005375_adipose_tissue_phenotype1.15051332
61MP0002234_abnormal_pharynx_morphology1.13385074
62MP0004085_abnormal_heartbeat1.08800691
63MP0002254_reproductive_system_inflammat1.07315930
64MP0002249_abnormal_larynx_morphology1.05614594
65MP0003828_pulmonary_edema1.03590418
66MP0002009_preneoplasia1.03517949
67MP0001299_abnormal_eye_distance/1.02585694
68MP0005670_abnormal_white_adipose1.02080841
69MP0001346_abnormal_lacrimal_gland1.01931244
70MP0002127_abnormal_cardiovascular_syste1.01732685
71MP0001730_embryonic_growth_arrest1.01451249
72MP0010094_abnormal_chromosome_stability0.99885352
73MP0004197_abnormal_fetal_growth/weight/0.98814255
74MP0005187_abnormal_penis_morphology0.96362499
75MP0005395_other_phenotype0.94403532
76MP0001672_abnormal_embryogenesis/_devel0.93784851
77MP0005380_embryogenesis_phenotype0.93784851
78MP0002697_abnormal_eye_size0.93396497
79MP0003984_embryonic_growth_retardation0.92870821
80MP0009703_decreased_birth_body0.92713974
81MP0005076_abnormal_cell_differentiation0.91208550
82MP0009780_abnormal_chondrocyte_physiolo0.90745855
83MP0004782_abnormal_surfactant_physiolog0.90163896
84MP0002088_abnormal_embryonic_growth/wei0.89906425
85MP0003111_abnormal_nucleus_morphology0.89596184
86MP0008438_abnormal_cutaneous_collagen0.89049196
87MP0000266_abnormal_heart_morphology0.88416086
88MP0003077_abnormal_cell_cycle0.86928276
89MP0002084_abnormal_developmental_patter0.84748677
90MP0003045_fibrosis0.83958517
91MP0002971_abnormal_brown_adipose0.82459204
92MP0002060_abnormal_skin_morphology0.82443900
93MP0003453_abnormal_keratinocyte_physiol0.82416386
94MP0006036_abnormal_mitochondrial_physio0.79195626
95MP0000427_abnormal_hair_cycle0.78460597
96MP0003011_delayed_dark_adaptation0.78147487
97MP0003252_abnormal_bile_duct0.77915969
98MP0008932_abnormal_embryonic_tissue0.77293790
99MP0005409_darkened_coat_color0.76950101
100MP0002653_abnormal_ependyma_morphology0.76577331
101MP0000013_abnormal_adipose_tissue0.76464532
102MP0000462_abnormal_digestive_system0.75912946
103MP0000003_abnormal_adipose_tissue0.75800106
104MP0000343_altered_response_to0.75611096
105MP0001188_hyperpigmentation0.75040721
106MP0003699_abnormal_female_reproductive0.74800641
107MP0000647_abnormal_sebaceous_gland0.74716939
108MP0008058_abnormal_DNA_repair0.73935224
109MP0010678_abnormal_skin_adnexa0.73837422
110MP0002086_abnormal_extraembryonic_tissu0.73804931
111MP0000627_abnormal_mammary_gland0.71664351
112MP0008961_abnormal_basal_metabolism0.71109007
113MP0002085_abnormal_embryonic_tissue0.70046352
114MP0000762_abnormal_tongue_morphology0.69360493
115MP0001849_ear_inflammation0.68518040
116MP0002108_abnormal_muscle_morphology0.67930091
117MP0003315_abnormal_perineum_morphology0.67855696
118MP0000767_abnormal_smooth_muscle0.67449864
119MP0005165_increased_susceptibility_to0.66129706
120MP0000350_abnormal_cell_proliferation0.66017852
121MP0005360_urolithiasis0.65854689
122MP0009250_abnormal_appendicular_skeleto0.65564852
123MP0001697_abnormal_embryo_size0.65525047
124MP0004264_abnormal_extraembryonic_tissu0.64171079
125MP0000383_abnormal_hair_follicle0.62911240
126MP0006072_abnormal_retinal_apoptosis0.60112410
127MP0004272_abnormal_basement_membrane0.58447775
128MP0005266_abnormal_metabolism0.57832713
129MP0002168_other_aberrant_phenotype0.57291199
130MP0002128_abnormal_blood_circulation0.57077696
131MP0003279_aneurysm0.56139797
132MP0005365_abnormal_bile_salt0.55812630
133MP0003937_abnormal_limbs/digits/tail_de0.55645132
134MP0002295_abnormal_pulmonary_circulatio0.55092851
135MP0005023_abnormal_wound_healing0.53551488
136MP0000377_abnormal_hair_follicle0.52443674
137MP0005501_abnormal_skin_physiology0.50906169
138MP0001666_abnormal_nutrient_absorption0.50856772
139MP0005408_hypopigmentation0.50064742
140MP0003941_abnormal_skin_development0.49497354
141MP0002098_abnormal_vibrissa_morphology0.49370086
142MP0003091_abnormal_cell_migration0.49246012

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)5.99707485
2Ventricular tachycardia (HP:0004756)5.76894828
3Muscle fiber splitting (HP:0003555)5.73416145
4Right ventricular cardiomyopathy (HP:0011663)5.70601656
5Exercise-induced myalgia (HP:0003738)5.49396797
6Calf muscle hypertrophy (HP:0008981)5.10918478
7Exercise-induced muscle cramps (HP:0003710)5.08776055
8Muscle hypertrophy of the lower extremities (HP:0008968)4.87596365
9Hyporeflexia of lower limbs (HP:0002600)4.67087171
10Increased connective tissue (HP:0009025)4.39722366
11Abnormality of the calf musculature (HP:0001430)4.25393702
12Muscle fiber inclusion bodies (HP:0100299)4.18769925
13Type 1 muscle fiber predominance (HP:0003803)4.16425479
14Atrial fibrillation (HP:0005110)4.15209053
15Abnormality of nail color (HP:0100643)4.08803188
16Myoglobinuria (HP:0002913)4.08705592
17Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)4.06794883
18Lipoatrophy (HP:0100578)4.05291889
19Subaortic stenosis (HP:0001682)3.91038925
20Abnormality of the left ventricular outflow tract (HP:0011103)3.91038925
21Primary atrial arrhythmia (HP:0001692)3.84970041
22Syncope (HP:0001279)3.84054420
23Difficulty running (HP:0009046)3.71826741
24Bundle branch block (HP:0011710)3.65428469
25Supraventricular tachycardia (HP:0004755)3.63878311
26Supraventricular arrhythmia (HP:0005115)3.57686262
27EMG: myopathic abnormalities (HP:0003458)3.47885982
28Ventricular arrhythmia (HP:0004308)3.40318272
29Hypoplastic ischia (HP:0003175)3.34624036
30Nemaline bodies (HP:0003798)3.34206161
31Rimmed vacuoles (HP:0003805)3.32833420
32Rhabdomyolysis (HP:0003201)3.27203416
33Dilated cardiomyopathy (HP:0001644)3.22818280
34Difficulty climbing stairs (HP:0003551)3.21245210
35Centrally nucleated skeletal muscle fibers (HP:0003687)3.18899028
36Asymmetric septal hypertrophy (HP:0001670)3.17995525
37Abnormality of the salivary glands (HP:0010286)3.17014375
38Heart block (HP:0012722)3.11888868
39Abnormal atrioventricular conduction (HP:0005150)3.09739753
40Atrioventricular block (HP:0001678)3.05214058
41Abnormality of the ischium (HP:0003174)2.98296458
42Ventricular fibrillation (HP:0001663)2.92441579
43Hyperglycemia (HP:0003074)2.91073940
44Myotonia (HP:0002486)2.90084526
45Hyperkalemia (HP:0002153)2.89912094
46Insulin-resistant diabetes mellitus (HP:0000831)2.85660416
47Onycholysis (HP:0001806)2.84101383
48Plantar hyperkeratosis (HP:0007556)2.83310456
49Palmoplantar hyperkeratosis (HP:0000972)2.78070180
50Palpitations (HP:0001962)2.76174201
51Palmar hyperkeratosis (HP:0010765)2.71370426
52Popliteal pterygium (HP:0009756)2.69715223
53Prolonged QT interval (HP:0001657)2.67929518
54Distal lower limb muscle weakness (HP:0009053)2.65666601
55Neck muscle weakness (HP:0000467)2.63172485
56Fatigable weakness (HP:0003473)2.61570927
57Abnormality of the neuromuscular junction (HP:0003398)2.61570927
58Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.51577058
59Central scotoma (HP:0000603)2.50980197
60Chorioretinal atrophy (HP:0000533)2.48575956
61Distal arthrogryposis (HP:0005684)2.46660771
62Absent eyelashes (HP:0000561)2.45478033
63Myopathic facies (HP:0002058)2.44895475
64Alopecia of scalp (HP:0002293)2.43806776
65Pili torti (HP:0003777)2.42506871
66Palmoplantar keratoderma (HP:0000982)2.42318991
67Mildly elevated creatine phosphokinase (HP:0008180)2.42263585
68Muscle stiffness (HP:0003552)2.36770003
69Areflexia of lower limbs (HP:0002522)2.35391067
70Increased variability in muscle fiber diameter (HP:0003557)2.34087213
71Hip contracture (HP:0003273)2.31685233
72Congenital ichthyosiform erythroderma (HP:0007431)2.31143287
73Male infertility (HP:0003251)2.31088667
74Round ear (HP:0100830)2.26784256
75Thick nail (HP:0001805)2.25631477
76Lip pit (HP:0100267)2.24987248
77EMG: neuropathic changes (HP:0003445)2.24489937
78Selective tooth agenesis (HP:0001592)2.24389048
79Ulnar deviation of the wrist (HP:0003049)2.23118589
80Abnormality of skeletal muscle fiber size (HP:0012084)2.22841536
81Fragile nails (HP:0001808)2.19967845
82Left ventricular hypertrophy (HP:0001712)2.17477362
83Scapular winging (HP:0003691)2.16060192
84Ketoacidosis (HP:0001993)2.15928662
85Gowers sign (HP:0003391)2.12414470
86Hypotrichosis (HP:0001006)2.11172980
87Hypoplastic labia majora (HP:0000059)2.10623694
88Abnormality of secondary sexual hair (HP:0009888)2.08962231
89Abnormality of the axillary hair (HP:0100134)2.08962231
90Abnormality of the labia majora (HP:0012881)2.08364063
91Distal lower limb amyotrophy (HP:0008944)2.07102908
92Pterygium (HP:0001059)2.06069449
93Depressed nasal tip (HP:0000437)2.02611278
94Pigmentary retinal degeneration (HP:0001146)1.98942626
95Frequent falls (HP:0002359)1.96687475
96Advanced eruption of teeth (HP:0006288)1.95629191
97Papillary thyroid carcinoma (HP:0002895)1.95270942
98Ankle contracture (HP:0006466)1.94716148
99Lower limb amyotrophy (HP:0007210)1.91178905
100Abnormal hair laboratory examination (HP:0003328)1.90838652
101Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.89677328
102Generalized muscle weakness (HP:0003324)1.88452092
103Gout (HP:0001997)1.87077481
104Progressive muscle weakness (HP:0003323)1.86592458
105Muscular dystrophy (HP:0003560)1.86215948
106Calcaneovalgus deformity (HP:0001848)1.85461852
107Bony spicule pigmentary retinopathy (HP:0007737)1.84560416
108Aneurysm (HP:0002617)1.83572103
109Erythroderma (HP:0001019)1.82115451
110Proximal amyotrophy (HP:0007126)1.81230973
111Protrusio acetabuli (HP:0003179)1.79856959
112Scotoma (HP:0000575)1.79839860
113Sparse eyelashes (HP:0000653)1.79263131
114Weak cry (HP:0001612)1.78388211
115Corneal erosion (HP:0200020)1.76461885
116Hypoalphalipoproteinemia (HP:0003233)1.75169525
117Absent phalangeal crease (HP:0006109)1.74333039
118Broad metatarsal (HP:0001783)1.74188187
119Limb-girdle muscle atrophy (HP:0003797)1.73227850
120Hypoglycemic coma (HP:0001325)1.71212974
121Flat capital femoral epiphysis (HP:0003370)1.70920213
122Absent hair (HP:0002298)1.70517532
123Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.70464119
124Abnormality of alanine metabolism (HP:0010916)1.70464119
125Hyperalaninemia (HP:0003348)1.70464119
126Amniotic constriction ring (HP:0009775)1.69875064
127Abnormality of placental membranes (HP:0011409)1.69875064
128Abnormal finger flexion creases (HP:0006143)1.69732666
129Dysmetric saccades (HP:0000641)1.69732165
130Deformed tarsal bones (HP:0008119)1.69200382
131Malignant hyperthermia (HP:0002047)1.68077440
132Milia (HP:0001056)1.67659910
133Ectropion (HP:0000656)1.67362410
134Wrist flexion contracture (HP:0001239)1.67080896
135Abnormality of the pubic bones (HP:0003172)1.66496234
136Shoulder girdle muscle weakness (HP:0003547)1.66201740
137Long toe (HP:0010511)1.65142415
138Flat acetabular roof (HP:0003180)1.65059032
139Abnormal EKG (HP:0003115)1.64475709
140Abnormality of permanent molar morphology (HP:0011071)1.64190252
141Abnormality of the dental root (HP:0006486)1.64190252
142Taurodontia (HP:0000679)1.64190252
143Sparse scalp hair (HP:0002209)1.62815427
144Neonatal death (HP:0003811)1.61977629
145Abnormality of the calcaneus (HP:0008364)1.61115781
146Bulbar palsy (HP:0001283)1.60964580
147Progressive external ophthalmoplegia (HP:0000590)1.60881399
148Duplicated collecting system (HP:0000081)1.60705013
149Curly hair (HP:0002212)1.58560172
150Biliary tract neoplasm (HP:0100574)1.58392968

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS14.12965970
2TTN3.99598184
3OBSCN3.38541835
4MUSK3.28569383
5MST1R2.97390615
6EEF2K2.96670096
7STK38L2.82482100
8MAPKAPK32.77578279
9MET2.48015576
10LATS22.47777823
11TAOK12.44239926
12DMPK2.43907443
13PBK2.33169741
14TRIB32.28950715
15PHKG22.26547894
16PHKG12.26547894
17KSR22.23365981
18MAP3K62.09392070
19MST41.98174386
20ERBB41.89413358
21TTK1.81296483
22CDK121.80441116
23LMTK21.79245628
24PKN21.78591074
25PDK41.69980879
26PDK31.69980879
27TRPM71.69616966
28TSSK61.69358036
29PIK3CA1.61397207
30TAOK31.48810753
31STK241.46174487
32CAMK1G1.43076444
33BRAF1.42320088
34PRKAA21.41398533
35STK31.31094695
36BCKDK1.28706972
37PINK11.28653666
38BRSK21.22200524
39TAF11.21539176
40MAP3K91.19931142
41MAP3K31.19331020
42EIF2AK31.17619102
43PRKAA11.13040423
44RIPK11.12703939
45PLK41.10796483
46PAK31.09164635
47FGFR11.05669698
48SIK11.04588729
49NEK11.03946315
50NEK91.02827557
51STK381.02797857
52RAF11.01044344
53MAP3K71.00659729
54PDK20.99587236
55PRKD30.99118436
56MYLK0.97290403
57SMG10.97016632
58EPHA30.95534294
59MAP3K130.95446917
60TNIK0.94968377
61MOS0.93275459
62PAK60.88602444
63MKNK20.87817481
64CDC70.87709317
65AKT30.87345932
66NME10.86095104
67RPS6KB20.85772527
68SRPK10.79466760
69PRKD20.79436960
70MAP3K50.78106236
71TGFBR10.77833882
72MELK0.76162276
73KSR10.74467145
74BUB10.74302237
75PIK3CG0.73007868
76FER0.71746129
77MAP3K20.71248902
78CDK90.70258178
79PRKD10.69620013
80MAPK120.69362667
81STK390.68842441
82ERBB30.68677418
83ZAK0.68299498
84MARK20.67692240
85EPHA20.66329516
86OXSR10.64395932
87BRD40.62934015
88ROCK10.62826899
89ICK0.62658969
90STK100.62032831
91RET0.61785196
92PDGFRA0.61112078
93PNCK0.60952606
94MAP3K100.60377901
95EPHB10.58206129
96MKNK10.58168918
97NEK60.56947299
98AKT20.55547673
99MAPK110.55200933
100PLK10.54433202
101CAMK2D0.53497167
102MAP2K30.53218481
103MAP3K10.52948026
104WNK40.52862408
105MAP2K10.51860611
106MAPKAPK50.51737894
107DDR20.50780877
108CHEK10.50738694
109PLK30.50151031
110AURKB0.49979987
111TIE10.49835764
112NUAK10.49058983
113BMX0.47626838
114PTK20.47088529
115RPS6KB10.45373505
116MTOR0.43925998
117SGK4940.42150588
118SGK2230.42150588
119ARAF0.42123531
120ACVR1B0.41450930
121MAP2K40.40274749
122CDK70.40272422
123CAMK2A0.39386469
124ATM0.39308635
125ERN10.39292125
126PRKCI0.38953298
127TRIM280.38897638
128INSRR0.38817662
129CSNK1E0.38811311
130WNK10.38638477
131FRK0.37752399
132SGK30.37095202
133SCYL20.36689994
134SGK20.36602782
135ILK0.36520914
136BCR0.36428655
137PTK60.33767048
138MAP3K120.33649724
139CAMK2G0.33332607
140PRKG20.33150640
141PAK40.31983890
142EIF2AK20.31806401
143CDK60.31229893
144MAP3K80.30889464
145WEE10.30472633
146CHEK20.28219581
147CDC42BPA0.26888525
148CDK10.26696654
149PRKDC0.25909674
150JAK20.23724366
151NEK20.23665483
152CDK80.23193162
153PRKCH0.22072507
154CAMK1D0.21927688
155PDGFRB0.21046333
156NLK0.20110055

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.71788176
2Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.29890992
3Dilated cardiomyopathy_Homo sapiens_hsa054143.17557702
42-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.90421434
5Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.76071505
6Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.61565643
7Propanoate metabolism_Homo sapiens_hsa006402.53924644
8Fatty acid degradation_Homo sapiens_hsa000712.46187346
9Circadian rhythm_Homo sapiens_hsa047102.37759350
10Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.99264366
11Thyroid cancer_Homo sapiens_hsa052161.96110894
12Ovarian steroidogenesis_Homo sapiens_hsa049131.95220642
13Cardiac muscle contraction_Homo sapiens_hsa042601.92194703
14Phototransduction_Homo sapiens_hsa047441.73998377
15Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.71621773
16alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.69520293
17Fatty acid metabolism_Homo sapiens_hsa012121.59478016
18Adherens junction_Homo sapiens_hsa045201.59436837
19Pyruvate metabolism_Homo sapiens_hsa006201.58954675
20Non-homologous end-joining_Homo sapiens_hsa034501.52187577
21Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.51787294
22Carbon metabolism_Homo sapiens_hsa012001.51653095
23Linoleic acid metabolism_Homo sapiens_hsa005911.50954872
24Insulin resistance_Homo sapiens_hsa049311.35989654
25RNA transport_Homo sapiens_hsa030131.33342976
26Starch and sucrose metabolism_Homo sapiens_hsa005001.31194312
27ECM-receptor interaction_Homo sapiens_hsa045121.25028922
28Mismatch repair_Homo sapiens_hsa034301.24643240
29Arginine biosynthesis_Homo sapiens_hsa002201.22613417
30Lysine degradation_Homo sapiens_hsa003101.20144022
31Pentose phosphate pathway_Homo sapiens_hsa000301.18448221
32Focal adhesion_Homo sapiens_hsa045101.16496858
33PPAR signaling pathway_Homo sapiens_hsa033201.16351974
34Viral myocarditis_Homo sapiens_hsa054161.13082232
35Tryptophan metabolism_Homo sapiens_hsa003801.12073854
36GnRH signaling pathway_Homo sapiens_hsa049121.11479151
37Glucagon signaling pathway_Homo sapiens_hsa049221.10896725
38Tight junction_Homo sapiens_hsa045301.10665641
39Fructose and mannose metabolism_Homo sapiens_hsa000511.09319456
40Insulin signaling pathway_Homo sapiens_hsa049101.08714664
41Pancreatic cancer_Homo sapiens_hsa052121.07942218
42AMPK signaling pathway_Homo sapiens_hsa041521.06605254
43Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.01949742
44Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.01570997
45Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.00061984
46Fatty acid biosynthesis_Homo sapiens_hsa000610.99097536
47DNA replication_Homo sapiens_hsa030300.97986847
48mRNA surveillance pathway_Homo sapiens_hsa030150.97145704
49Adipocytokine signaling pathway_Homo sapiens_hsa049200.95366810
50Longevity regulating pathway - mammal_Homo sapiens_hsa042110.94200119
51Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.93483569
52beta-Alanine metabolism_Homo sapiens_hsa004100.93436061
53TGF-beta signaling pathway_Homo sapiens_hsa043500.91809039
54Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.91481386
55Vitamin digestion and absorption_Homo sapiens_hsa049770.91217623
56Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.89650822
57Fat digestion and absorption_Homo sapiens_hsa049750.89436848
58Thyroid hormone signaling pathway_Homo sapiens_hsa049190.89384184
59Arginine and proline metabolism_Homo sapiens_hsa003300.88400311
60Vitamin B6 metabolism_Homo sapiens_hsa007500.88195108
61Selenocompound metabolism_Homo sapiens_hsa004500.88002039
62Oocyte meiosis_Homo sapiens_hsa041140.87801896
63Biosynthesis of amino acids_Homo sapiens_hsa012300.87329300
64Dorso-ventral axis formation_Homo sapiens_hsa043200.87068852
65Histidine metabolism_Homo sapiens_hsa003400.86036230
66VEGF signaling pathway_Homo sapiens_hsa043700.84715018
67Protein digestion and absorption_Homo sapiens_hsa049740.84037588
68cGMP-PKG signaling pathway_Homo sapiens_hsa040220.82983874
69Prolactin signaling pathway_Homo sapiens_hsa049170.82156413
70Small cell lung cancer_Homo sapiens_hsa052220.81933018
71Bladder cancer_Homo sapiens_hsa052190.80116100
72Renal cell carcinoma_Homo sapiens_hsa052110.79231718
73Butanoate metabolism_Homo sapiens_hsa006500.79111598
74Amoebiasis_Homo sapiens_hsa051460.78578405
75mTOR signaling pathway_Homo sapiens_hsa041500.78573698
76Wnt signaling pathway_Homo sapiens_hsa043100.77726712
77Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.77622398
78Nucleotide excision repair_Homo sapiens_hsa034200.77352386
79Hippo signaling pathway_Homo sapiens_hsa043900.76388845
80FoxO signaling pathway_Homo sapiens_hsa040680.75806449
81Oxytocin signaling pathway_Homo sapiens_hsa049210.73270144
82Vascular smooth muscle contraction_Homo sapiens_hsa042700.69615001
83Caffeine metabolism_Homo sapiens_hsa002320.67207636
84Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.66191755
85RNA degradation_Homo sapiens_hsa030180.63108613
86Nitrogen metabolism_Homo sapiens_hsa009100.61616130
87Choline metabolism in cancer_Homo sapiens_hsa052310.60380571
88Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.59979714
89Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.59939907
90Sphingolipid metabolism_Homo sapiens_hsa006000.59876141
91Glycerophospholipid metabolism_Homo sapiens_hsa005640.59779671
92Steroid biosynthesis_Homo sapiens_hsa001000.59377889
93Galactose metabolism_Homo sapiens_hsa000520.59355219
94Prostate cancer_Homo sapiens_hsa052150.58890519
95Basal transcription factors_Homo sapiens_hsa030220.57876254
96Proteoglycans in cancer_Homo sapiens_hsa052050.57737368
97MicroRNAs in cancer_Homo sapiens_hsa052060.57677960
98Endometrial cancer_Homo sapiens_hsa052130.57557840
99Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.57372325
100Basal cell carcinoma_Homo sapiens_hsa052170.56034936
101Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.55974314
102Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.53857097
103Ether lipid metabolism_Homo sapiens_hsa005650.53851557
104p53 signaling pathway_Homo sapiens_hsa041150.53312682
105Cell cycle_Homo sapiens_hsa041100.52825032
106Type II diabetes mellitus_Homo sapiens_hsa049300.51210759
107Glycerolipid metabolism_Homo sapiens_hsa005610.50745619
108One carbon pool by folate_Homo sapiens_hsa006700.50576951
109Calcium signaling pathway_Homo sapiens_hsa040200.50497507
110HIF-1 signaling pathway_Homo sapiens_hsa040660.50396112
111Central carbon metabolism in cancer_Homo sapiens_hsa052300.50363877
112Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.49161068
113Phosphatidylinositol signaling system_Homo sapiens_hsa040700.48276957
114Fatty acid elongation_Homo sapiens_hsa000620.48251252
115Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.47871926
116Cysteine and methionine metabolism_Homo sapiens_hsa002700.47717080
117Pancreatic secretion_Homo sapiens_hsa049720.46925815
118Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.45478179
119Pentose and glucuronate interconversions_Homo sapiens_hsa000400.44939051
120Notch signaling pathway_Homo sapiens_hsa043300.44915074
121Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.43462879
122Phenylalanine metabolism_Homo sapiens_hsa003600.43329653
123Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.43049431
124Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.42234031
125Inositol phosphate metabolism_Homo sapiens_hsa005620.41500005
126Arachidonic acid metabolism_Homo sapiens_hsa005900.40226811
127Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.39865676
128cAMP signaling pathway_Homo sapiens_hsa040240.39291121
129Peroxisome_Homo sapiens_hsa041460.38819125
130Chronic myeloid leukemia_Homo sapiens_hsa052200.36887641
131Regulation of actin cytoskeleton_Homo sapiens_hsa048100.35802650
132Bile secretion_Homo sapiens_hsa049760.32498389
133AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.32140461
134Ras signaling pathway_Homo sapiens_hsa040140.29211022
135Estrogen signaling pathway_Homo sapiens_hsa049150.28985442

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