FAHD2A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.99115333
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.74663835
3L-phenylalanine catabolic process (GO:0006559)4.74663835
4mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.58880456
5NADH metabolic process (GO:0006734)4.54832480
6ATP synthesis coupled proton transport (GO:0015986)4.50731985
7energy coupled proton transport, down electrochemical gradient (GO:0015985)4.50731985
8erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.45782516
9L-phenylalanine metabolic process (GO:0006558)4.45782516
10oxaloacetate metabolic process (GO:0006107)4.35286954
11respiratory electron transport chain (GO:0022904)4.30128981
12electron transport chain (GO:0022900)4.21053581
13aromatic amino acid family catabolic process (GO:0009074)4.06973128
14glyoxylate metabolic process (GO:0046487)4.03848492
15branched-chain amino acid catabolic process (GO:0009083)3.93807429
16succinate metabolic process (GO:0006105)3.91614363
17drug transmembrane transport (GO:0006855)3.90431948
18serine family amino acid catabolic process (GO:0009071)3.90144078
19lysine metabolic process (GO:0006553)3.89366583
20lysine catabolic process (GO:0006554)3.89366583
21tricarboxylic acid cycle (GO:0006099)3.87626165
22short-chain fatty acid metabolic process (GO:0046459)3.86529803
23pyrimidine nucleobase catabolic process (GO:0006208)3.82377488
24L-serine metabolic process (GO:0006563)3.82158432
25regulation of cholesterol esterification (GO:0010872)3.77587918
26glycine metabolic process (GO:0006544)3.75066747
27valine metabolic process (GO:0006573)3.71791887
28branched-chain amino acid metabolic process (GO:0009081)3.71041036
29cellular ketone body metabolic process (GO:0046950)3.66993937
30fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.59182050
31aspartate family amino acid catabolic process (GO:0009068)3.56762410
32fatty acid beta-oxidation (GO:0006635)3.41109927
33bile acid biosynthetic process (GO:0006699)3.41015411
342-oxoglutarate metabolic process (GO:0006103)3.39778263
35indole-containing compound catabolic process (GO:0042436)3.36750875
36indolalkylamine catabolic process (GO:0046218)3.36750875
37tryptophan catabolic process (GO:0006569)3.36750875
38aldehyde catabolic process (GO:0046185)3.34999738
39regulation of mitochondrial translation (GO:0070129)3.34048807
40fatty acid catabolic process (GO:0009062)3.33567190
41acetyl-CoA metabolic process (GO:0006084)3.32211634
42response to pheromone (GO:0019236)3.30551805
43mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.26717914
44mitochondrial respiratory chain complex I assembly (GO:0032981)3.26717914
45NADH dehydrogenase complex assembly (GO:0010257)3.26717914
46aerobic respiration (GO:0009060)3.23365654
47protein complex biogenesis (GO:0070271)3.21695800
48tricarboxylic acid metabolic process (GO:0072350)3.18585614
49monocarboxylic acid catabolic process (GO:0072329)3.17781322
50oxidative phosphorylation (GO:0006119)3.17712180
51drug transport (GO:0015893)3.17013535
52cullin deneddylation (GO:0010388)3.15454197
53ketone body metabolic process (GO:1902224)3.15309009
54cellular biogenic amine catabolic process (GO:0042402)3.15129328
55amine catabolic process (GO:0009310)3.15129328
56fatty acid oxidation (GO:0019395)3.13725736
57tryptophan metabolic process (GO:0006568)3.13498262
58rRNA modification (GO:0000154)3.13075392
59respiratory chain complex IV assembly (GO:0008535)3.12537477
60dopamine transport (GO:0015872)3.12197808
61aminoglycoside antibiotic metabolic process (GO:0030647)3.11916104
62serine family amino acid metabolic process (GO:0009069)3.11776460
63peroxisome fission (GO:0016559)3.10240102
64coenzyme catabolic process (GO:0009109)3.09493983
65serine family amino acid biosynthetic process (GO:0009070)3.08406591
66lipid oxidation (GO:0034440)3.07647367
67nucleobase catabolic process (GO:0046113)3.07400773
68ethanol oxidation (GO:0006069)3.06002657
69cysteine metabolic process (GO:0006534)3.05810733
70NAD metabolic process (GO:0019674)3.05800056
71peptidyl-arginine omega-N-methylation (GO:0035247)3.03739248
72amino acid salvage (GO:0043102)3.03050739
73L-methionine salvage (GO:0071267)3.03050739
74L-methionine biosynthetic process (GO:0071265)3.03050739
75alpha-amino acid catabolic process (GO:1901606)3.02028077
76organic cation transport (GO:0015695)2.99750771
77mitochondrial respiratory chain complex assembly (GO:0033108)2.97654180
78acyl-CoA metabolic process (GO:0006637)2.97406457
79thioester metabolic process (GO:0035383)2.97406457
80aromatic amino acid family metabolic process (GO:0009072)2.95130511
81establishment of protein localization to mitochondrial membrane (GO:0090151)2.93822551
82organic acid catabolic process (GO:0016054)2.93326968
83carboxylic acid catabolic process (GO:0046395)2.93326968
84water-soluble vitamin biosynthetic process (GO:0042364)2.92981156
85very long-chain fatty acid metabolic process (GO:0000038)2.92846723
86chaperone-mediated protein transport (GO:0072321)2.92414135
87cellular amino acid catabolic process (GO:0009063)2.92086873
88ATP biosynthetic process (GO:0006754)2.86951877
89hydrogen ion transmembrane transport (GO:1902600)2.86583790
90rRNA methylation (GO:0031167)2.86572449
91glycoside metabolic process (GO:0016137)2.86398926
92nonribosomal peptide biosynthetic process (GO:0019184)2.85159359
93glutathione metabolic process (GO:0006749)2.83941346
94sulfur amino acid catabolic process (GO:0000098)2.83728006
95S-adenosylmethionine metabolic process (GO:0046500)2.83721363
96response to mercury ion (GO:0046689)2.83334509
97ATP hydrolysis coupled proton transport (GO:0015991)2.83216718
98energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.83216718
99fatty acid elongation (GO:0030497)2.82207405
100regulation of oxidative phosphorylation (GO:0002082)2.80813128
101drug catabolic process (GO:0042737)2.79653055
102kynurenine metabolic process (GO:0070189)2.79103025
103metallo-sulfur cluster assembly (GO:0031163)2.79086897
104iron-sulfur cluster assembly (GO:0016226)2.79086897
105peptidyl-histidine modification (GO:0018202)2.79037795
106termination of RNA polymerase III transcription (GO:0006386)2.78791001
107transcription elongation from RNA polymerase III promoter (GO:0006385)2.78791001
108glutamate metabolic process (GO:0006536)2.76359479
109DNA ligation (GO:0006266)2.75381292
110exogenous drug catabolic process (GO:0042738)2.74981662
111hydrogen transport (GO:0006818)2.73536208
112cofactor catabolic process (GO:0051187)2.73321147
113regulation of acyl-CoA biosynthetic process (GO:0050812)2.73141159
114cytochrome complex assembly (GO:0017004)2.72816878
115acyl-CoA biosynthetic process (GO:0071616)2.70232067
116thioester biosynthetic process (GO:0035384)2.70232067
117base-excision repair, AP site formation (GO:0006285)2.70040601
118ubiquinone biosynthetic process (GO:0006744)2.69953803
119quinone biosynthetic process (GO:1901663)2.69953803
120protein deneddylation (GO:0000338)2.69178763
121urate metabolic process (GO:0046415)2.68847825
122bile acid metabolic process (GO:0008206)2.66802257
123sperm motility (GO:0030317)2.66330114
124histone arginine methylation (GO:0034969)2.66216936
125proton transport (GO:0015992)2.66146631
126establishment of integrated proviral latency (GO:0075713)2.65505651
127L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.65205908
128amino-acid betaine metabolic process (GO:0006577)2.64499958
129regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.63044708
130glutathione biosynthetic process (GO:0006750)2.62112300
131purine nucleoside triphosphate biosynthetic process (GO:0009145)2.60353008
132small molecule catabolic process (GO:0044282)2.60151447
133purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.60112272
134oxidative demethylation (GO:0070989)2.57785150
135DNA replication checkpoint (GO:0000076)2.57271778
136peptidyl-arginine methylation (GO:0018216)2.57246411
137peptidyl-arginine N-methylation (GO:0035246)2.57246411
138pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.56226974
139mannosylation (GO:0097502)2.51923002
140establishment of mitochondrion localization (GO:0051654)2.49899673
141negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.49674699
142epoxygenase P450 pathway (GO:0019373)2.47580725
143methionine metabolic process (GO:0006555)2.45955436
144deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.43792159
145sulfur amino acid biosynthetic process (GO:0000097)2.43474674
146methionine biosynthetic process (GO:0009086)2.43184485
147arginine catabolic process (GO:0006527)2.42520835
148aspartate family amino acid biosynthetic process (GO:0009067)2.40499877
149proteasome assembly (GO:0043248)2.37470302
150deoxyribonucleotide catabolic process (GO:0009264)2.37461884
151cholesterol biosynthetic process (GO:0006695)2.37362078
152negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.37263968
153pseudouridine synthesis (GO:0001522)2.35930843
154arginine metabolic process (GO:0006525)2.35172017
155chromatin remodeling at centromere (GO:0031055)2.30707466
156microtubule depolymerization (GO:0007019)2.30409418
157spliceosomal snRNP assembly (GO:0000387)2.30013003
158regulation of cellular amino acid metabolic process (GO:0006521)2.29527873
159purine nucleobase biosynthetic process (GO:0009113)2.28939525
160sterol biosynthetic process (GO:0016126)2.28399595
161behavioral response to nicotine (GO:0035095)2.27124363
162vitamin biosynthetic process (GO:0009110)2.25392491
163negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.24505783
164negative regulation of ligase activity (GO:0051352)2.24505783
165aspartate family amino acid metabolic process (GO:0009066)2.23830589

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.85523329
2EZH2_22144423_ChIP-Seq_EOC_Human3.90691383
3EGR1_23403033_ChIP-Seq_LIVER_Mouse3.09577722
4RXR_22158963_ChIP-Seq_LIVER_Mouse3.08612043
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.03322924
6TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.97697746
7ETS1_20019798_ChIP-Seq_JURKAT_Human2.97684098
8MYC_18555785_ChIP-Seq_MESCs_Mouse2.82501132
9GBX2_23144817_ChIP-Seq_PC3_Human2.72678127
10TAF15_26573619_Chip-Seq_HEK293_Human2.61214607
11* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.54195157
12NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.52826751
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.45612998
14ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.43116111
15CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.37845510
16TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.36934123
17XRN2_22483619_ChIP-Seq_HELA_Human2.29592148
18CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.29209135
19SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.29203808
20PPARA_22158963_ChIP-Seq_LIVER_Mouse2.29170516
21YY1_21170310_ChIP-Seq_MESCs_Mouse2.27492277
22FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.23831271
23EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.18483760
24PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.17929889
25MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.16999089
26CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.15185184
27VDR_22108803_ChIP-Seq_LS180_Human2.09394038
28LXR_22158963_ChIP-Seq_LIVER_Mouse2.03267494
29GABP_19822575_ChIP-Seq_HepG2_Human2.00485619
30E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.00060007
31CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.95930798
32MYC_19030024_ChIP-ChIP_MESCs_Mouse1.94121497
33ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.93442847
34CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.83018417
35FOXP3_21729870_ChIP-Seq_TREG_Human1.82853077
36KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.82444289
37E2F7_22180533_ChIP-Seq_HELA_Human1.80536455
38E2F1_18555785_ChIP-Seq_MESCs_Mouse1.79595953
39TTF2_22483619_ChIP-Seq_HELA_Human1.76244045
40VDR_23849224_ChIP-Seq_CD4+_Human1.70353975
41E2F4_17652178_ChIP-ChIP_JURKAT_Human1.70353972
42DCP1A_22483619_ChIP-Seq_HELA_Human1.64340551
43MYC_19079543_ChIP-ChIP_MESCs_Mouse1.64024323
44ZFP57_27257070_Chip-Seq_ESCs_Mouse1.62530463
45SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.62384294
46LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.59515108
47CTBP2_25329375_ChIP-Seq_LNCAP_Human1.56112621
48PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.55166187
49SRF_21415370_ChIP-Seq_HL-1_Mouse1.53177901
50SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.49068279
51DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.47795012
52MYC_18940864_ChIP-ChIP_HL60_Human1.47320189
53CIITA_25753668_ChIP-Seq_RAJI_Human1.47096581
54YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.46894666
55FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.42745797
56HTT_18923047_ChIP-ChIP_STHdh_Human1.39628872
57CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.39057237
58* FOXP1_21924763_ChIP-Seq_HESCs_Human1.38090268
59TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.36637330
60FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.35310643
61NELFA_20434984_ChIP-Seq_ESCs_Mouse1.33601250
62KDM5A_27292631_Chip-Seq_BREAST_Human1.33373147
63REST_18959480_ChIP-ChIP_MESCs_Mouse1.32944485
64POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.31871171
65SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.31285876
66ZNF274_21170338_ChIP-Seq_K562_Hela1.29970857
67BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.29081139
68JARID2_20064375_ChIP-Seq_MESCs_Mouse1.29057104
69SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.28967906
70SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.28912080
71FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.28805696
72POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.28402044
73MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.27315466
74TET1_21451524_ChIP-Seq_MESCs_Mouse1.26341024
75PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.26202296
76MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.25836537
77GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25285487
78MTF2_20144788_ChIP-Seq_MESCs_Mouse1.23060979
79IGF1R_20145208_ChIP-Seq_DFB_Human1.22359061
80EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.22162871
81SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.21955575
82* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.21497770
83SUZ12_27294783_Chip-Seq_ESCs_Mouse1.21378214
84YY1_22570637_ChIP-Seq_MALME-3M_Human1.21196290
85JARID2_20075857_ChIP-Seq_MESCs_Mouse1.21152563
86P300_19829295_ChIP-Seq_ESCs_Human1.19148217
87PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.18822902
88CTBP1_25329375_ChIP-Seq_LNCAP_Human1.18583008
89BCL6_27268052_Chip-Seq_Bcells_Human1.18152908
90REST_21632747_ChIP-Seq_MESCs_Mouse1.17580728
91POU3F2_20337985_ChIP-ChIP_501MEL_Human1.16776882
92EZH2_27294783_Chip-Seq_ESCs_Mouse1.16113040
93HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.15414587
94EED_16625203_ChIP-ChIP_MESCs_Mouse1.15162096
95SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.14775726
96ELF1_20517297_ChIP-Seq_JURKAT_Human1.11541616
97ELF1_17652178_ChIP-ChIP_JURKAT_Human1.11046524
98EZH2_27304074_Chip-Seq_ESCs_Mouse1.09654636
99IRF8_22096565_ChIP-ChIP_GC-B_Human1.09472798
100SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.09002323
101TAL1_26923725_Chip-Seq_HPCs_Mouse1.08765375
102NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.08552484
103GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.08052549
104MYCN_18555785_ChIP-Seq_MESCs_Mouse1.07539712
105RAD21_21589869_ChIP-Seq_MESCs_Mouse1.06525508
106BMI1_23680149_ChIP-Seq_NPCS_Mouse1.06255324
107P68_20966046_ChIP-Seq_HELA_Human1.06241914
108PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.05837328
109PHF8_20622854_ChIP-Seq_HELA_Human1.05829976
110* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.05263304
111RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.03647296
112E2F1_20622854_ChIP-Seq_HELA_Human1.02468228
113MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.99088857
114DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.98742837
115PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.98489844
116ERA_21632823_ChIP-Seq_H3396_Human0.97452100
117E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.97405483
118IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.96808682
119CBP_20019798_ChIP-Seq_JUKART_Human0.96808682
120CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.95671691
121CBX2_27304074_Chip-Seq_ESCs_Mouse0.95147553
122ZFX_18555785_ChIP-Seq_MESCs_Mouse0.94806429
123KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.94202673
124ETV2_25802403_ChIP-Seq_MESCs_Mouse0.93937737
125HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.93738758
126UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.93413260
127ER_23166858_ChIP-Seq_MCF-7_Human0.92239356
128SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.91829060
129NANOG_19829295_ChIP-Seq_ESCs_Human0.91483526
130SOX2_19829295_ChIP-Seq_ESCs_Human0.91483526
131AR_20517297_ChIP-Seq_VCAP_Human0.91447542
132CTCF_20526341_ChIP-Seq_ESCs_Human0.90492271
133RNF2_18974828_ChIP-Seq_MESCs_Mouse0.89930164
134EZH2_18974828_ChIP-Seq_MESCs_Mouse0.89930164
135SOX2_16153702_ChIP-ChIP_HESCs_Human0.89922099
136SMAD4_21799915_ChIP-Seq_A2780_Human0.89879012
137CTCF_27219007_Chip-Seq_Bcells_Human0.89531359
138SRY_22984422_ChIP-ChIP_TESTIS_Rat0.89419657
139RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.89247390
140* HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.88984234
141TP63_19390658_ChIP-ChIP_HaCaT_Human0.88453614
142LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.88415402
143NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.88010594
144AR_25329375_ChIP-Seq_VCAP_Human0.87944173
145PADI4_21655091_ChIP-ChIP_MCF-7_Human0.86516641
146CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.86369550
147P53_21459846_ChIP-Seq_SAOS-2_Human0.85831289
148ESR1_15608294_ChIP-ChIP_MCF-7_Human0.85503752
149ELK1_19687146_ChIP-ChIP_HELA_Human0.85461426
150HOXB4_20404135_ChIP-ChIP_EML_Mouse0.85356050
151ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.84953708
152NANOG_20526341_ChIP-Seq_ESCs_Human0.84865286
153IRF1_19129219_ChIP-ChIP_H3396_Human0.84585484
154PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.84280131
155RUNX1_27457419_Chip-Seq_LIVER_Mouse0.83583970
156E2F1_17053090_ChIP-ChIP_MCF-7_Human0.83372471
157TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.81866897
158* SOX2_22085726_ChIP-Seq_NPCs_Mouse0.81161154
159HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.80805695
160CTCF_18555785_ChIP-Seq_MESCs_Mouse0.80781381
161MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.80768997
162GABP_17652178_ChIP-ChIP_JURKAT_Human0.80647886
163AUTS2_25519132_ChIP-Seq_293T-REX_Human0.80619071
164RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.79164820
165PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.79140331
166GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.76960547
167EST1_17652178_ChIP-ChIP_JURKAT_Human0.76762951
168KDM2B_26808549_Chip-Seq_REH_Human0.76707069
169TAF2_19829295_ChIP-Seq_ESCs_Human0.75457978
170GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.75427980
171THAP11_20581084_ChIP-Seq_MESCs_Mouse0.75158913

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system4.51042696
2MP0003195_calcinosis3.87637462
3MP0005360_urolithiasis3.78448902
4MP0008875_abnormal_xenobiotic_pharmacok3.49483744
5MP0005365_abnormal_bile_salt3.13281811
6MP0005085_abnormal_gallbladder_physiolo2.90488996
7MP0002837_dystrophic_cardiac_calcinosis2.84673788
8MP0005332_abnormal_amino_acid2.67334617
9MP0006036_abnormal_mitochondrial_physio2.58969227
10MP0006292_abnormal_olfactory_placode2.58252651
11MP0003806_abnormal_nucleotide_metabolis2.56900131
12MP0002876_abnormal_thyroid_physiology2.35427048
13MP0004043_abnormal_pH_regulation2.29673289
14MP0005423_abnormal_somatic_nervous2.27519403
15MP0003880_abnormal_central_pattern2.22788180
16MP0005410_abnormal_fertilization2.19557388
17MP0008058_abnormal_DNA_repair2.16074904
18MP0009697_abnormal_copulation2.05694402
19MP0001905_abnormal_dopamine_level2.04537020
20MP0003718_maternal_effect2.02018810
21MP0003693_abnormal_embryo_hatching2.01427223
22MP0005394_taste/olfaction_phenotype1.93799103
23MP0005499_abnormal_olfactory_system1.93799103
24MP0002822_catalepsy1.90713244
25MP0008789_abnormal_olfactory_epithelium1.89682434
26MP0006276_abnormal_autonomic_nervous1.86586296
27MP0010094_abnormal_chromosome_stability1.77799081
28MP0001529_abnormal_vocalization1.74624348
29MP0003252_abnormal_bile_duct1.73068990
30MP0003879_abnormal_hair_cell1.72488346
31MP0002234_abnormal_pharynx_morphology1.69171142
32MP0004019_abnormal_vitamin_homeostasis1.68958767
33MP0005584_abnormal_enzyme/coenzyme_acti1.68949209
34MP0003122_maternal_imprinting1.68186511
35MP0005535_abnormal_body_temperature1.66824955
36MP0008932_abnormal_embryonic_tissue1.66779912
37MP0005379_endocrine/exocrine_gland_phen1.64860137
38MP0010329_abnormal_lipoprotein_level1.63799574
39MP0005636_abnormal_mineral_homeostasis1.63456575
40MP0004142_abnormal_muscle_tone1.62003867
41MP0005646_abnormal_pituitary_gland1.61863836
42MP0003186_abnormal_redox_activity1.59044752
43MP0002138_abnormal_hepatobiliary_system1.58453359
44MP0009745_abnormal_behavioral_response1.57748577
45MP0008995_early_reproductive_senescence1.56792686
46MP0001764_abnormal_homeostasis1.54257668
47MP0002272_abnormal_nervous_system1.53834078
48MP0009379_abnormal_foot_pigmentation1.53543865
49MP0000013_abnormal_adipose_tissue1.52885855
50MP0005084_abnormal_gallbladder_morpholo1.49617383
51MP0006035_abnormal_mitochondrial_morpho1.49367827
52MP0001293_anophthalmia1.49225517
53MP0003646_muscle_fatigue1.48361817
54MP0002064_seizures1.48024036
55MP0003011_delayed_dark_adaptation1.45435957
56MP0001968_abnormal_touch/_nociception1.43720670
57MP0001501_abnormal_sleep_pattern1.41140740
58MP0002118_abnormal_lipid_homeostasis1.37096930
59MP0003698_abnormal_male_reproductive1.36986262
60MP0005409_darkened_coat_color1.36653924
61MP0001765_abnormal_ion_homeostasis1.35919034
62MP0003111_abnormal_nucleus_morphology1.35515864
63MP0002249_abnormal_larynx_morphology1.34987002
64MP0002736_abnormal_nociception_after1.34973685
65MP0002572_abnormal_emotion/affect_behav1.34755697
66MP0009643_abnormal_urine_homeostasis1.33959160
67MP0003635_abnormal_synaptic_transmissio1.33504124
68MP0008007_abnormal_cellular_replicative1.33323529
69MP0003329_amyloid_beta_deposits1.32847938
70MP0002909_abnormal_adrenal_gland1.32823849
71MP0004036_abnormal_muscle_relaxation1.32449850
72MP0000751_myopathy1.30316594
73MP0001666_abnormal_nutrient_absorption1.28711616
74MP0000049_abnormal_middle_ear1.28298149
75MP0001929_abnormal_gametogenesis1.28079045
76MP0002653_abnormal_ependyma_morphology1.27004577
77MP0002938_white_spotting1.26542123
78MP0003878_abnormal_ear_physiology1.24620179
79MP0005377_hearing/vestibular/ear_phenot1.24620179
80MP0005670_abnormal_white_adipose1.24038055
81MP0000778_abnormal_nervous_system1.22786712
82MP0005083_abnormal_biliary_tract1.20724081
83MP0008872_abnormal_physiological_respon1.19413811
84MP0003077_abnormal_cell_cycle1.18788676
85MP0003786_premature_aging1.17726188
86MP0003656_abnormal_erythrocyte_physiolo1.16876417
87MP0001486_abnormal_startle_reflex1.16726938
88MP0005319_abnormal_enzyme/_coenzyme1.16517766
89MP0004130_abnormal_muscle_cell1.16049703
90MP0000749_muscle_degeneration1.14498670
91MP0002063_abnormal_learning/memory/cond1.14189817
92MP0004133_heterotaxia1.13754990
93MP0003121_genomic_imprinting1.12311175
94MP0004147_increased_porphyrin_level1.11704091
95MP0006072_abnormal_retinal_apoptosis1.11430253
96MP0004957_abnormal_blastocyst_morpholog1.10254000
97MP0008877_abnormal_DNA_methylation1.08652178
98MP0002067_abnormal_sensory_capabilities1.07886668
99MP0005551_abnormal_eye_electrophysiolog1.02448258
100MP0001986_abnormal_taste_sensitivity1.02341032
101MP0001502_abnormal_circadian_rhythm1.01619412
102MP0001188_hyperpigmentation1.01214918
103MP0000230_abnormal_systemic_arterial1.00272003
104MP0009046_muscle_twitch0.98338913
105MP0005451_abnormal_body_composition0.97585152
106MP0005645_abnormal_hypothalamus_physiol0.94537347
107MP0002078_abnormal_glucose_homeostasis0.94402894
108MP0003137_abnormal_impulse_conducting0.93765640
109MP0002210_abnormal_sex_determination0.93258802
110MP0001440_abnormal_grooming_behavior0.93222238
111MP0000955_abnormal_spinal_cord0.92428070
112MP0010030_abnormal_orbit_morphology0.91755375
113MP0004859_abnormal_synaptic_plasticity0.90232041
114MP0004270_analgesia0.89513725
115MP0010386_abnormal_urinary_bladder0.89043088
116MP0005253_abnormal_eye_physiology0.88508382
117MP0002161_abnormal_fertility/fecundity0.87496061
118MP0002638_abnormal_pupillary_reflex0.85746126
119MP0001984_abnormal_olfaction0.85104319
120MP0000604_amyloidosis0.84769484
121MP0001145_abnormal_male_reproductive0.83740327
122MP0003136_yellow_coat_color0.83230745
123MP0000920_abnormal_myelination0.83163023
124MP0005386_behavior/neurological_phenoty0.82853575
125MP0004924_abnormal_behavior0.82853575
126MP0003119_abnormal_digestive_system0.81697818
127MP0009840_abnormal_foam_cell0.81587018
128MP0002734_abnormal_mechanical_nocicepti0.81539121
129MP0000653_abnormal_sex_gland0.80326285
130MP0004215_abnormal_myocardial_fiber0.80094857
131MP0002229_neurodegeneration0.79692522
132MP0003191_abnormal_cellular_cholesterol0.79304856
133MP0003868_abnormal_feces_composition0.79204722
134MP0005171_absent_coat_pigmentation0.78847325
135MP0002282_abnormal_trachea_morphology0.78051096
136MP0008874_decreased_physiological_sensi0.77961052
137MP0001756_abnormal_urination0.77337320
138MP0004145_abnormal_muscle_electrophysio0.76913693
139MP0009642_abnormal_blood_homeostasis0.76679562
140MP0001970_abnormal_pain_threshold0.75669521
141MP0002735_abnormal_chemical_nociception0.75270077
142MP0000372_irregular_coat_pigmentation0.75162610
143MP0002733_abnormal_thermal_nociception0.74084468
144MP0002882_abnormal_neuron_morphology0.74036222
145MP0004811_abnormal_neuron_physiology0.73397600
146MP0001963_abnormal_hearing_physiology0.73081216
147MP0000609_abnormal_liver_physiology0.72997828
148MP0002332_abnormal_exercise_endurance0.70530503
149MP0002557_abnormal_social/conspecific_i0.69948927
150MP0004742_abnormal_vestibular_system0.69340056
151MP0003953_abnormal_hormone_level0.68874915
152MP0003787_abnormal_imprinting0.68058072
153MP0005330_cardiomyopathy0.67006489
154MP0001664_abnormal_digestion0.67003785
155MP0008469_abnormal_protein_level0.66897494

Predicted human phenotypes

RankGene SetZ-score
1Hepatocellular necrosis (HP:0001404)4.48437817
2Hepatic necrosis (HP:0002605)4.39358008
3Acute necrotizing encephalopathy (HP:0006965)4.35770824
4Mitochondrial inheritance (HP:0001427)4.28347385
5Abnormal mitochondria in muscle tissue (HP:0008316)4.24493741
6Acute encephalopathy (HP:0006846)4.15988509
7Abnormality of aromatic amino acid family metabolism (HP:0004338)4.04771032
8Increased CSF lactate (HP:0002490)3.78034451
9Cerebral edema (HP:0002181)3.77610242
10Abnormality of glycolysis (HP:0004366)3.76656811
11Increased serum pyruvate (HP:0003542)3.76656811
12Progressive macrocephaly (HP:0004481)3.74215308
13Ketosis (HP:0001946)3.59796867
14Renal Fanconi syndrome (HP:0001994)3.55928504
15Ketoacidosis (HP:0001993)3.55757793
16Generalized aminoaciduria (HP:0002909)3.38112227
17Lactic acidosis (HP:0003128)3.29083555
18Increased intramyocellular lipid droplets (HP:0012240)3.27650662
19Increased muscle lipid content (HP:0009058)3.23136426
20Abnormality of fatty-acid metabolism (HP:0004359)3.19340172
21Gout (HP:0001997)3.10565334
22Abnormality of dicarboxylic acid metabolism (HP:0010995)3.06283839
23Dicarboxylic aciduria (HP:0003215)3.06283839
24Hyperglycinuria (HP:0003108)2.94435408
25Lethargy (HP:0001254)2.90521688
26Abnormality of urine glucose concentration (HP:0011016)2.89122668
27Glycosuria (HP:0003076)2.89122668
28Colon cancer (HP:0003003)2.88656486
29Lipid accumulation in hepatocytes (HP:0006561)2.87299225
30Hyperventilation (HP:0002883)2.85479735
31Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.81702682
32Metabolic acidosis (HP:0001942)2.77452571
33Abnormality of serine family amino acid metabolism (HP:0010894)2.77346864
34Abnormality of glycine metabolism (HP:0010895)2.77346864
35Reduced antithrombin III activity (HP:0001976)2.76514599
36Increased hepatocellular lipid droplets (HP:0006565)2.75870877
37Abnormality of renal resorption (HP:0011038)2.71656836
38Hyperammonemia (HP:0001987)2.68735726
39Conjugated hyperbilirubinemia (HP:0002908)2.65784432
40Pheochromocytoma (HP:0002666)2.64053756
413-Methylglutaconic aciduria (HP:0003535)2.62671959
42Respiratory failure (HP:0002878)2.61263443
43Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.58080888
44Decreased activity of mitochondrial respiratory chain (HP:0008972)2.58080888
45Increased serum lactate (HP:0002151)2.57736666
46Abnormality of alanine metabolism (HP:0010916)2.55016826
47Hyperalaninemia (HP:0003348)2.55016826
48Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.55016826
49Neuroendocrine neoplasm (HP:0100634)2.54770911
50Type I transferrin isoform profile (HP:0003642)2.53594864
51Abnormality of magnesium homeostasis (HP:0004921)2.50516967
52Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.50005256
53Impulsivity (HP:0100710)2.48363265
54Vomiting (HP:0002013)2.46364353
55Hypomagnesemia (HP:0002917)2.46261644
56Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.45956898
57Intrahepatic cholestasis (HP:0001406)2.45042805
58Abnormality of the labia minora (HP:0012880)2.43602582
59Hypoglycemic coma (HP:0001325)2.42384672
60Exercise intolerance (HP:0003546)2.40143178
61Cholecystitis (HP:0001082)2.37867091
62Abnormal gallbladder physiology (HP:0012438)2.37867091
63Focal motor seizures (HP:0011153)2.36897434
64Prolonged partial thromboplastin time (HP:0003645)2.35430419
65Abnormality of aspartate family amino acid metabolism (HP:0010899)2.35240172
66Methylmalonic aciduria (HP:0012120)2.34717777
67Optic disc pallor (HP:0000543)2.32475398
68Increased circulating renin level (HP:0000848)2.32180811
69Delayed CNS myelination (HP:0002188)2.29653378
70Myokymia (HP:0002411)2.28881660
71Hyperlipoproteinemia (HP:0010980)2.28686503
72Cerebral hypomyelination (HP:0006808)2.28662045
73Hyperphosphaturia (HP:0003109)2.27648036
74Hyperglycinemia (HP:0002154)2.27267823
75Leukodystrophy (HP:0002415)2.24443708
76Opisthotonus (HP:0002179)2.21249079
77Molar tooth sign on MRI (HP:0002419)2.21083572
78Abnormality of midbrain morphology (HP:0002418)2.21083572
79Xanthomatosis (HP:0000991)2.20552229
80Ragged-red muscle fibers (HP:0003200)2.20064429
81Cerebral palsy (HP:0100021)2.18744333
82Abnormality of glutamine family amino acid metabolism (HP:0010902)2.17318090
83Polyuria (HP:0000103)2.16784962
84Abnormality of serum amino acid levels (HP:0003112)2.15278561
85Reticulocytopenia (HP:0001896)2.14937943
86Medial flaring of the eyebrow (HP:0010747)2.14715574
87Cholelithiasis (HP:0001081)2.12376387
88Abnormal drinking behavior (HP:0030082)2.11307629
89Polydipsia (HP:0001959)2.11307629
90Abnormal protein glycosylation (HP:0012346)2.10946209
91Abnormal glycosylation (HP:0012345)2.10946209
92Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.10946209
93Abnormal protein N-linked glycosylation (HP:0012347)2.10946209
94Hyperbilirubinemia (HP:0002904)2.10290145
95CNS demyelination (HP:0007305)2.10198013
96Nephronophthisis (HP:0000090)2.09190557
97Microvesicular hepatic steatosis (HP:0001414)2.09157334
98Abnormal urine output (HP:0012590)2.06864134
99Alkalosis (HP:0001948)2.06012906
100Hypoplastic pelvis (HP:0008839)2.03165183
101Abnormality of purine metabolism (HP:0004352)2.03041785
102Gait imbalance (HP:0002141)2.02330321
103Hypophosphatemic rickets (HP:0004912)2.02300896
104Renal tubular dysfunction (HP:0000124)2.00863919
105Acute hepatic failure (HP:0006554)2.00671303
106Hypokalemic alkalosis (HP:0001949)1.99940667
107Methylmalonic acidemia (HP:0002912)1.99280470
108Myoglobinuria (HP:0002913)1.99108159
109Abnormal urine phosphate concentration (HP:0012599)1.98808745
110Failure to thrive in infancy (HP:0001531)1.98684716
111Fat malabsorption (HP:0002630)1.96317534
112Sclerocornea (HP:0000647)1.95832382
113Hypobetalipoproteinemia (HP:0003563)1.94958135
114Abnormality of sulfur amino acid metabolism (HP:0004339)1.94166571
115Poor suck (HP:0002033)1.93668065
116Abnormality of pyrimidine metabolism (HP:0004353)1.93297354
117Polyphagia (HP:0002591)1.93082424
118Abnormal gallbladder morphology (HP:0012437)1.92704948
119Abnormality of monocarboxylic acid metabolism (HP:0010996)1.92505693
120Nephrogenic diabetes insipidus (HP:0009806)1.91189614
121Retinal dysplasia (HP:0007973)1.91175439
122Spontaneous abortion (HP:0005268)1.91067207
123Tubulointerstitial nephritis (HP:0001970)1.91050948
124Hyperuricemia (HP:0002149)1.89864622
125Increased purine levels (HP:0004368)1.89864622
126Cerebral hemorrhage (HP:0001342)1.89141013
127Hypothermia (HP:0002045)1.88843564
128Abnormality of methionine metabolism (HP:0010901)1.88832651
129Pancreatic islet-cell hyperplasia (HP:0004510)1.88590300
130Emotional lability (HP:0000712)1.88125457
131Congenital primary aphakia (HP:0007707)1.87591262
132Abnormality of the ileum (HP:0001549)1.86415555
133Deep venous thrombosis (HP:0002625)1.85022123
134Meckel diverticulum (HP:0002245)1.84808939
135Multiple enchondromatosis (HP:0005701)1.81519188
136Muscle fiber atrophy (HP:0100295)1.76442844
137CNS hypomyelination (HP:0003429)1.76357579
138Type 2 muscle fiber atrophy (HP:0003554)1.75633728
139Degeneration of anterior horn cells (HP:0002398)1.74417834
140Abnormality of the anterior horn cell (HP:0006802)1.74417834
141Bile duct proliferation (HP:0001408)1.74178610
142Abnormal biliary tract physiology (HP:0012439)1.74178610
143Abnormal number of erythroid precursors (HP:0012131)1.73364896
144Pancreatic fibrosis (HP:0100732)1.72059887

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK4.76622303
2VRK24.61470435
3STK164.04788392
4MAP3K123.73634474
5MAP4K23.45902582
6WNK42.95878616
7OXSR12.84467084
8BUB12.71749354
9MYLK2.69689624
10PINK12.67501455
11CASK2.63160308
12INSRR2.52203906
13TNIK2.37141727
14VRK12.36670684
15BMPR1B2.26236351
16CDC72.21126379
17ZAK2.20123102
18PDK32.19458765
19PDK42.19458765
20SRPK12.18081085
21PLK42.11611227
22MAP2K72.09944176
23CDK192.09096372
24NUAK12.02583612
25STK391.97823665
26DYRK21.93733644
27MARK11.87757842
28WNK31.79295029
29MUSK1.75362306
30NME11.75117642
31PBK1.74804592
32IRAK21.64689953
33CSNK1G21.50114333
34NME21.48513985
35TLK11.44183936
36MAP2K41.41409633
37CSNK1A1L1.39078119
38MAP2K61.37397509
39TRIM281.32968401
40EPHA41.29831868
41CSNK1G11.28312958
42GRK71.23004373
43SIK31.22130943
44TESK11.21457259
45PLK31.21158416
46PLK11.20765718
47BMPR21.19733301
48TAOK31.18430753
49PRKD31.18245615
50BRSK11.17706567
51DYRK31.17542165
52ADRBK21.17321954
53TNK21.13305959
54TTK1.10847348
55BCR1.09871608
56TGFBR11.09531357
57OBSCN1.06828881
58MKNK11.04896768
59SGK4941.04549722
60SGK2231.04549722
61TESK21.04464451
62PDK21.04154569
63TAF11.02322077
64FLT31.01648499
65NEK11.01577100
66PLK21.00398719
67FES0.99992939
68ARAF0.98926976
69ATR0.98071475
70IRAK10.97942152
71MAP3K40.95582896
72PHKG20.94927038
73PHKG10.94927038
74KIT0.89974801
75RIPK40.87140831
76WNK10.86554823
77CHEK20.86474865
78CAMKK20.83159189
79CDK80.82238459
80PIM20.80906892
81MAPK150.80635168
82GRK50.78954086
83MKNK20.76235896
84TYK20.76038759
85LMTK20.75785224
86PAK60.74668769
87MAPK40.74595039
88LIMK10.74578867
89AURKA0.73643779
90CCNB10.70601255
91CDK11A0.70372971
92ADRBK10.70140167
93CAMK2A0.67367977
94CAMK2B0.66691972
95CDK140.66278458
96BRAF0.65811218
97BRSK20.64256251
98TXK0.64109218
99DAPK10.62650497
100ABL20.62497910
101CDK150.61841864
102CDK180.61636589
103NEK20.60405337
104MINK10.59792370
105CAMK2G0.58758606
106AURKB0.58391334
107SYK0.58274475
108CAMK10.57845911
109SGK20.57782145
110CDK70.57585395
111NEK60.57031860
112DAPK30.56954070
113CLK10.54723441
114PRKACA0.53774222
115MAPK70.53108742
116UHMK10.52603286
117MAP3K60.51966867
118PIK3CG0.51306481
119CHEK10.51269311
120NTRK30.50616151
121CSNK2A10.49673225
122MAPK130.49167456
123MAP3K130.47919502
124MAPKAPK50.46083664
125KDR0.45693676
126NTRK20.45077771
127GRK60.44907141
128CDK20.44124522
129PRKCQ0.44014147
130ATM0.43163973
131CAMK2D0.42932360
132IRAK40.42273452
133PRKDC0.42028446
134PRPF4B0.41983773
135ERBB30.41812736
136CSNK2A20.41075504
137RPS6KA50.40678999
138BTK0.39481660
139PRKCG0.39264774
140CSNK1A10.38366516
141CAMK1D0.38273428
142SIK20.37771728
143CDK10.37043921
144TIE10.36970358
145NTRK10.36911052
146CDK50.36882626
147PRKACB0.36321081
148PKN10.35295686
149PRKCE0.35125301
150YES10.33758864
151PDPK10.33351777
152ACVR1B0.32855461
153FGFR40.32505394
154MAPK120.32501153
155ERBB40.32351568
156CDK30.31722673
157TAOK20.30718347
158DYRK1A0.30131526
159PRKCA0.28928229
160CSNK1G30.28620483
161LYN0.28095057
162SIK10.27727132

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001903.41491363
2Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.15580713
3Propanoate metabolism_Homo sapiens_hsa006403.14552400
4Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.83011433
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.82469574
6Parkinsons disease_Homo sapiens_hsa050122.77513525
7Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.65562104
8Fatty acid elongation_Homo sapiens_hsa000622.59986132
9Pyruvate metabolism_Homo sapiens_hsa006202.53396885
10Butanoate metabolism_Homo sapiens_hsa006502.53170339
11Primary bile acid biosynthesis_Homo sapiens_hsa001202.43626135
122-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.32991531
13Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.31051474
14Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.18604802
15Fatty acid degradation_Homo sapiens_hsa000712.16954064
16Peroxisome_Homo sapiens_hsa041462.13904808
17Alzheimers disease_Homo sapiens_hsa050102.01658290
18Fatty acid metabolism_Homo sapiens_hsa012121.98337630
19RNA polymerase_Homo sapiens_hsa030201.86557572
20Collecting duct acid secretion_Homo sapiens_hsa049661.83364731
21Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.82697601
22Base excision repair_Homo sapiens_hsa034101.82489250
23Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.81365328
24Tryptophan metabolism_Homo sapiens_hsa003801.75937578
25beta-Alanine metabolism_Homo sapiens_hsa004101.74565873
26Sulfur metabolism_Homo sapiens_hsa009201.71049235
27DNA replication_Homo sapiens_hsa030301.69721710
28Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.69595095
29Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.68912483
30Mismatch repair_Homo sapiens_hsa034301.68514279
31Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.67281036
32Homologous recombination_Homo sapiens_hsa034401.66537808
33Carbon metabolism_Homo sapiens_hsa012001.63884092
34Huntingtons disease_Homo sapiens_hsa050161.61723596
35Fanconi anemia pathway_Homo sapiens_hsa034601.54393817
36Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.50106893
37Caffeine metabolism_Homo sapiens_hsa002321.48950644
38Pentose and glucuronate interconversions_Homo sapiens_hsa000401.43804502
39Histidine metabolism_Homo sapiens_hsa003401.35924688
40Phenylalanine metabolism_Homo sapiens_hsa003601.34277149
41Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.22838484
42Protein export_Homo sapiens_hsa030601.20685634
43Non-homologous end-joining_Homo sapiens_hsa034501.19686092
44Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.19049207
45Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.18739289
46One carbon pool by folate_Homo sapiens_hsa006701.17609416
47Chemical carcinogenesis_Homo sapiens_hsa052041.17066273
48Pyrimidine metabolism_Homo sapiens_hsa002401.16939152
49Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.15173028
50Cardiac muscle contraction_Homo sapiens_hsa042601.13594217
51Steroid hormone biosynthesis_Homo sapiens_hsa001401.13442778
52Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.13013063
53Arginine biosynthesis_Homo sapiens_hsa002201.08049573
54Tyrosine metabolism_Homo sapiens_hsa003501.07877874
55PPAR signaling pathway_Homo sapiens_hsa033201.07747944
56Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.04976177
57Folate biosynthesis_Homo sapiens_hsa007901.04613384
58Biosynthesis of amino acids_Homo sapiens_hsa012301.04504002
59Cysteine and methionine metabolism_Homo sapiens_hsa002701.03048527
60Spliceosome_Homo sapiens_hsa030401.01599248
61Synaptic vesicle cycle_Homo sapiens_hsa047211.00108482
62Starch and sucrose metabolism_Homo sapiens_hsa005000.97842295
63Nicotine addiction_Homo sapiens_hsa050330.97679761
64Maturity onset diabetes of the young_Homo sapiens_hsa049500.94671522
65Nucleotide excision repair_Homo sapiens_hsa034200.94607928
66Drug metabolism - other enzymes_Homo sapiens_hsa009830.94203209
67RNA transport_Homo sapiens_hsa030130.90309572
68Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.88361669
69Metabolic pathways_Homo sapiens_hsa011000.87548842
70Arginine and proline metabolism_Homo sapiens_hsa003300.87244170
71Vibrio cholerae infection_Homo sapiens_hsa051100.85796619
72Selenocompound metabolism_Homo sapiens_hsa004500.83836282
73Glutathione metabolism_Homo sapiens_hsa004800.82775050
74Retinol metabolism_Homo sapiens_hsa008300.74960855
75Cyanoamino acid metabolism_Homo sapiens_hsa004600.74485072
76Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.72905619
77Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.72809640
78Complement and coagulation cascades_Homo sapiens_hsa046100.69794655
79Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.69108680
80RNA degradation_Homo sapiens_hsa030180.68306287
81Fructose and mannose metabolism_Homo sapiens_hsa000510.66337358
82Linoleic acid metabolism_Homo sapiens_hsa005910.61162434
83Basal transcription factors_Homo sapiens_hsa030220.59690652
84GABAergic synapse_Homo sapiens_hsa047270.58518607
85Pentose phosphate pathway_Homo sapiens_hsa000300.58381940
86Glycerolipid metabolism_Homo sapiens_hsa005610.56127670
87Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.55881097
88Galactose metabolism_Homo sapiens_hsa000520.55707595
89Bile secretion_Homo sapiens_hsa049760.53449597
90Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.51256602
91Proteasome_Homo sapiens_hsa030500.50877815
92SNARE interactions in vesicular transport_Homo sapiens_hsa041300.49781983
93ABC transporters_Homo sapiens_hsa020100.48282061
94Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.47095602
95Steroid biosynthesis_Homo sapiens_hsa001000.46247212
96Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.46109946
97Sulfur relay system_Homo sapiens_hsa041220.44924580
98Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.44309235
99Rheumatoid arthritis_Homo sapiens_hsa053230.43809879
100Taste transduction_Homo sapiens_hsa047420.43755585
101Morphine addiction_Homo sapiens_hsa050320.42733369
102Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.41830299
103Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.40729896
104Glycosaminoglycan degradation_Homo sapiens_hsa005310.39813027
105Arachidonic acid metabolism_Homo sapiens_hsa005900.37016299
106Cell cycle_Homo sapiens_hsa041100.36543231
107Vitamin B6 metabolism_Homo sapiens_hsa007500.34866560
108Oocyte meiosis_Homo sapiens_hsa041140.33104675
109Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.31290060
110Vitamin digestion and absorption_Homo sapiens_hsa049770.31036134
111Serotonergic synapse_Homo sapiens_hsa047260.30949049
112mRNA surveillance pathway_Homo sapiens_hsa030150.28877425
113Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.27332186
114Ribosome_Homo sapiens_hsa030100.25730090
115Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.23539772
116Fat digestion and absorption_Homo sapiens_hsa049750.22955451
117Circadian entrainment_Homo sapiens_hsa047130.21494171
118Other glycan degradation_Homo sapiens_hsa005110.20152928
119Cocaine addiction_Homo sapiens_hsa050300.19213008
120Lysine degradation_Homo sapiens_hsa003100.17994346
121Renin secretion_Homo sapiens_hsa049240.16972627
122Insulin secretion_Homo sapiens_hsa049110.16573667
123Fatty acid biosynthesis_Homo sapiens_hsa000610.16547356
124Purine metabolism_Homo sapiens_hsa002300.16243326
125Amphetamine addiction_Homo sapiens_hsa050310.15985063
126Dopaminergic synapse_Homo sapiens_hsa047280.15757990
127Regulation of autophagy_Homo sapiens_hsa041400.15456996

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