EXOSC7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)6.07798201
2ribosomal small subunit assembly (GO:0000028)5.47657669
3maturation of SSU-rRNA (GO:0030490)5.08977577
4proteasome assembly (GO:0043248)4.97868717
5chaperone-mediated protein transport (GO:0072321)4.63967885
6ribosomal small subunit biogenesis (GO:0042274)4.63905204
7purine nucleobase biosynthetic process (GO:0009113)4.54535298
8nucleobase biosynthetic process (GO:0046112)4.54190456
9viral transcription (GO:0019083)4.54045356
10DNA strand elongation involved in DNA replication (GO:0006271)4.47360621
11rRNA modification (GO:0000154)4.45660503
12translational termination (GO:0006415)4.43813988
13telomere maintenance via semi-conservative replication (GO:0032201)4.37969402
14ribosomal large subunit biogenesis (GO:0042273)4.31563660
15DNA strand elongation (GO:0022616)4.28598940
16mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.28083559
17negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.25730183
18ribonucleoprotein complex biogenesis (GO:0022613)4.23750504
19pseudouridine synthesis (GO:0001522)4.21466869
20transcription elongation from RNA polymerase III promoter (GO:0006385)4.20073512
21termination of RNA polymerase III transcription (GO:0006386)4.20073512
22formation of translation preinitiation complex (GO:0001731)4.19255871
23CENP-A containing nucleosome assembly (GO:0034080)4.15003172
24ribosome biogenesis (GO:0042254)4.11867986
25DNA replication initiation (GO:0006270)4.07864486
26translational elongation (GO:0006414)4.06035104
27SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.05782186
28positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.00643439
29regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.00560516
30respiratory electron transport chain (GO:0022904)3.99335887
31cotranslational protein targeting to membrane (GO:0006613)3.99300891
32chromatin remodeling at centromere (GO:0031055)3.96198020
33DNA replication checkpoint (GO:0000076)3.95978799
34protein targeting to ER (GO:0045047)3.94897667
35anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.94774849
36deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.93915917
37electron transport chain (GO:0022900)3.91597180
38telomere maintenance via recombination (GO:0000722)3.91558261
39* rRNA processing (GO:0006364)3.91082190
40translational initiation (GO:0006413)3.90246259
41negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.87703467
42negative regulation of ligase activity (GO:0051352)3.87703467
43protein complex biogenesis (GO:0070271)3.87599774
44mitochondrial respiratory chain complex assembly (GO:0033108)3.82625033
45ribosome assembly (GO:0042255)3.79878970
46protein localization to endoplasmic reticulum (GO:0070972)3.79664996
47regulation of cellular amino acid metabolic process (GO:0006521)3.78123936
48spliceosomal snRNP assembly (GO:0000387)3.77105058
49* rRNA metabolic process (GO:0016072)3.76549556
50mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.76003894
51mitochondrial respiratory chain complex I assembly (GO:0032981)3.76003894
52NADH dehydrogenase complex assembly (GO:0010257)3.76003894
53establishment of protein localization to endoplasmic reticulum (GO:0072599)3.74255876
547-methylguanosine mRNA capping (GO:0006370)3.73516723
55translation (GO:0006412)3.68918532
56rRNA methylation (GO:0031167)3.67840855
577-methylguanosine RNA capping (GO:0009452)3.67670747
58RNA capping (GO:0036260)3.67670747
59cellular component biogenesis (GO:0044085)3.65257319
60L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.63745145
61DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.63638471
62regulation of mitochondrial translation (GO:0070129)3.60095459
63signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.60054151
64signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.60054151
65signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.60054151
66respiratory chain complex IV assembly (GO:0008535)3.59931528
67intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.59113957
68signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.59113957
69mitotic recombination (GO:0006312)3.56770509
70mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.55117244
71nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.54193994
72transcription-coupled nucleotide-excision repair (GO:0006283)3.53767231
73signal transduction involved in DNA integrity checkpoint (GO:0072401)3.52425374
74signal transduction involved in DNA damage checkpoint (GO:0072422)3.52425374
75cellular protein complex disassembly (GO:0043624)3.51257754
76viral life cycle (GO:0019058)3.50945690
77DNA replication-independent nucleosome assembly (GO:0006336)3.49867217
78DNA replication-independent nucleosome organization (GO:0034724)3.49867217
79viral mRNA export from host cell nucleus (GO:0046784)3.49552473
80protein neddylation (GO:0045116)3.48428218
81signal transduction involved in cell cycle checkpoint (GO:0072395)3.47121224
82telomere maintenance via telomere lengthening (GO:0010833)3.45592186
83DNA double-strand break processing (GO:0000729)3.44683464
84positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.42224070
85spliceosomal complex assembly (GO:0000245)3.40590049
86transcription elongation from RNA polymerase I promoter (GO:0006362)3.39725750
87termination of RNA polymerase I transcription (GO:0006363)3.38111051
88protein targeting to mitochondrion (GO:0006626)3.38025428
89maturation of 5.8S rRNA (GO:0000460)3.37122560
90antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.35733270
91regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.33342840
92regulation of mitotic spindle checkpoint (GO:1903504)3.33342840
93RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.32667778
94tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.32667778
95* exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.30853836
96cytochrome complex assembly (GO:0017004)3.28738958
97peptidyl-histidine modification (GO:0018202)3.28604435
98positive regulation of ligase activity (GO:0051351)3.28344421
99kinetochore assembly (GO:0051382)3.25981021
100* nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.24915902
101G1/S transition of mitotic cell cycle (GO:0000082)3.24831074
102cell cycle G1/S phase transition (GO:0044843)3.24831074
103histone exchange (GO:0043486)3.24776015
104DNA catabolic process, exonucleolytic (GO:0000738)3.24283446
105mitotic metaphase plate congression (GO:0007080)3.23827169
106DNA unwinding involved in DNA replication (GO:0006268)3.23081001
107transcription from RNA polymerase I promoter (GO:0006360)3.22777273
108amino acid salvage (GO:0043102)3.21476624
109L-methionine salvage (GO:0071267)3.21476624
110L-methionine biosynthetic process (GO:0071265)3.21476624
111nucleotide-excision repair, DNA gap filling (GO:0006297)3.21136872
112energy coupled proton transport, down electrochemical gradient (GO:0015985)3.20990729
113ATP synthesis coupled proton transport (GO:0015986)3.20990729
114establishment of protein localization to mitochondrial membrane (GO:0090151)3.17985987
115kinetochore organization (GO:0051383)3.17970967
116establishment of protein localization to mitochondrion (GO:0072655)3.17953417
117IMP biosynthetic process (GO:0006188)3.17139754
118DNA damage response, detection of DNA damage (GO:0042769)3.16273465
119protein localization to mitochondrion (GO:0070585)3.14873607
120oxidative phosphorylation (GO:0006119)3.11932620
121establishment of integrated proviral latency (GO:0075713)3.11484887
122cullin deneddylation (GO:0010388)3.11217337
123protein deneddylation (GO:0000338)3.11149583
124replication fork processing (GO:0031297)3.10817020
125antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.10314025
126regulation of ubiquitin-protein transferase activity (GO:0051438)3.08374180
127inner mitochondrial membrane organization (GO:0007007)3.07774273
128regulation of ligase activity (GO:0051340)2.96903362
129histone mRNA metabolic process (GO:0008334)2.94080932

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.13745093
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.51683707
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.32679100
4EST1_17652178_ChIP-ChIP_JURKAT_Human3.94148274
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.89374041
6* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.85221442
7* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.82997869
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.55900949
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.38361164
10MYC_18358816_ChIP-ChIP_MESCs_Mouse3.21250289
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.20106468
12CREB1_15753290_ChIP-ChIP_HEK293T_Human3.19812631
13E2F4_17652178_ChIP-ChIP_JURKAT_Human3.08014349
14SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.01725865
15E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.00511281
16* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.97140269
17MYC_19079543_ChIP-ChIP_MESCs_Mouse2.95735036
18VDR_23849224_ChIP-Seq_CD4+_Human2.71148230
19ELF1_17652178_ChIP-ChIP_JURKAT_Human2.70126110
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.67722131
21HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.67075624
22FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.60513729
23CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.46136356
24XRN2_22483619_ChIP-Seq_HELA_Human2.45229698
25FOXP3_21729870_ChIP-Seq_TREG_Human2.33245489
26E2F1_18555785_ChIP-Seq_MESCs_Mouse2.31681210
27NELFA_20434984_ChIP-Seq_ESCs_Mouse2.30953335
28DCP1A_22483619_ChIP-Seq_HELA_Human2.27124747
29THAP11_20581084_ChIP-Seq_MESCs_Mouse2.20597619
30* SRF_21415370_ChIP-Seq_HL-1_Mouse2.16006935
31GABP_19822575_ChIP-Seq_HepG2_Human2.10438019
32YY1_21170310_ChIP-Seq_MESCs_Mouse2.09459979
33TTF2_22483619_ChIP-Seq_HELA_Human2.03315737
34FOXM1_23109430_ChIP-Seq_U2OS_Human1.97996433
35* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.94368607
36SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.92047540
37PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.91643839
38PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.89857294
39ELK1_19687146_ChIP-ChIP_HELA_Human1.83474961
40MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.80044416
41POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.78907682
42ZNF274_21170338_ChIP-Seq_K562_Hela1.78391934
43NANOG_18555785_ChIP-Seq_MESCs_Mouse1.77874437
44MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.77609936
45ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.75985974
46MYCN_18555785_ChIP-Seq_MESCs_Mouse1.72081503
47YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.71437696
48* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.69592796
49HOXB4_20404135_ChIP-ChIP_EML_Mouse1.69485142
50MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.69246521
51CIITA_25753668_ChIP-Seq_RAJI_Human1.61961353
52FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.60313016
53AR_21909140_ChIP-Seq_LNCAP_Human1.57441867
54E2F1_21310950_ChIP-Seq_MCF-7_Human1.48762352
55ZFX_18555785_ChIP-Seq_MESCs_Mouse1.47653326
56* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.47460575
57VDR_22108803_ChIP-Seq_LS180_Human1.47048312
58NOTCH1_21737748_ChIP-Seq_TLL_Human1.41042166
59EWS_26573619_Chip-Seq_HEK293_Human1.39944720
60* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.36068769
61KDM5A_27292631_Chip-Seq_BREAST_Human1.31812982
62POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.30152518
63FLI1_27457419_Chip-Seq_LIVER_Mouse1.26341174
64MYC_18940864_ChIP-ChIP_HL60_Human1.23401638
65FUS_26573619_Chip-Seq_HEK293_Human1.20089775
66ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.19650602
67ELK1_22589737_ChIP-Seq_MCF10A_Human1.19047321
68BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.18216300
69* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.17727172
70CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.16355344
71NANOG_16153702_ChIP-ChIP_HESCs_Human1.15771695
72POU5F1_16153702_ChIP-ChIP_HESCs_Human1.15611558
73SOX2_16153702_ChIP-ChIP_HESCs_Human1.13749127
74CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.11949621
75HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.10547075
76FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.10519587
77SALL1_21062744_ChIP-ChIP_HESCs_Human1.09585387
78IRF1_19129219_ChIP-ChIP_H3396_Human1.04974523
79CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.04595355
80E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.02820844
81* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.02168771
82CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.99522574
83* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.98399832
84STAT3_1855785_ChIP-Seq_MESCs_Mouse0.94784960
85* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.93587852
86POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.93437010
87CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.92673298
88DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.92628499
89CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.92336229
90TP53_22573176_ChIP-Seq_HFKS_Human0.90604390
91KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.90571137
92* SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.90096334
93PCGF2_27294783_Chip-Seq_ESCs_Mouse0.88951916
94SPI1_23547873_ChIP-Seq_NB4_Human0.88748747
95* KLF4_18555785_ChIP-Seq_MESCs_Mouse0.87173665
96TFEB_21752829_ChIP-Seq_HELA_Human0.86540000
97SOX2_18555785_ChIP-Seq_MESCs_Mouse0.85200933
98MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.85153447
99EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.84489261
100FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.83715469
101RBPJ_22232070_ChIP-Seq_NCS_Mouse0.83468995
102ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.83017781
103CTCF_18555785_ChIP-Seq_MESCs_Mouse0.81244204
104DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.80385968
105HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.79717620
106GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.78701306
107NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.75919101
108IGF1R_20145208_ChIP-Seq_DFB_Human0.74816193
109HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.74162665
110SOX17_20123909_ChIP-Seq_XEN_Mouse0.74004355
111POU3F2_20337985_ChIP-ChIP_501MEL_Human0.73756419
112SRY_22984422_ChIP-ChIP_TESTIS_Rat0.72431615
113TP63_19390658_ChIP-ChIP_HaCaT_Human0.71254653
114* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.70748591
115P300_19829295_ChIP-Seq_ESCs_Human0.69499999
116SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.69333676
117IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.69246250
118TBX5_21415370_ChIP-Seq_HL-1_Mouse0.67967818
119FOXA1_27270436_Chip-Seq_PROSTATE_Human0.62715322
120FOXA1_25329375_ChIP-Seq_VCAP_Human0.62715322

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching6.08496647
2MP0004957_abnormal_blastocyst_morpholog4.77117064
3MP0010094_abnormal_chromosome_stability4.45120077
4MP0003111_abnormal_nucleus_morphology4.16106060
5MP0008058_abnormal_DNA_repair3.99991127
6MP0008057_abnormal_DNA_replication3.73674630
7MP0003077_abnormal_cell_cycle3.71613709
8MP0008007_abnormal_cellular_replicative2.87973866
9MP0009379_abnormal_foot_pigmentation2.79799121
10MP0003718_maternal_effect2.77763182
11MP0003806_abnormal_nucleotide_metabolis2.63610795
12MP0002396_abnormal_hematopoietic_system2.60842857
13MP0008932_abnormal_embryonic_tissue2.58537980
14MP0002102_abnormal_ear_morphology2.48676244
15MP0003786_premature_aging2.46495366
16MP0008877_abnormal_DNA_methylation2.18616011
17MP0003123_paternal_imprinting2.06688895
18MP0006036_abnormal_mitochondrial_physio2.01467856
19MP0006292_abnormal_olfactory_placode1.94763524
20MP0006072_abnormal_retinal_apoptosis1.91208388
21MP0001730_embryonic_growth_arrest1.78897025
22MP0005075_abnormal_melanosome_morpholog1.78780812
23MP0003186_abnormal_redox_activity1.75437281
24MP0006035_abnormal_mitochondrial_morpho1.65083550
25MP0002132_abnormal_respiratory_system1.64676394
26MP0000490_abnormal_crypts_of1.62588462
27MP0004147_increased_porphyrin_level1.62330225
28MP0009333_abnormal_splenocyte_physiolog1.57401567
29MP0003315_abnormal_perineum_morphology1.54844943
30MP0000350_abnormal_cell_proliferation1.54010792
31MP0008789_abnormal_olfactory_epithelium1.52325228
32MP0003763_abnormal_thymus_physiology1.51919106
33MP0009697_abnormal_copulation1.51659772
34MP0001986_abnormal_taste_sensitivity1.43022423
35MP0001764_abnormal_homeostasis1.37898756
36MP0008260_abnormal_autophagy1.37826965
37MP0000313_abnormal_cell_death1.36600671
38MP0002234_abnormal_pharynx_morphology1.28767573
39MP0002736_abnormal_nociception_after1.28749950
40MP0002837_dystrophic_cardiac_calcinosis1.28544074
41MP0002019_abnormal_tumor_incidence1.28317929
42MP0005551_abnormal_eye_electrophysiolog1.26113189
43MP0001529_abnormal_vocalization1.23312140
44MP0003567_abnormal_fetal_cardiomyocyte1.22709598
45MP0002095_abnormal_skin_pigmentation1.22152260
46MP0005645_abnormal_hypothalamus_physiol1.22079456
47MP0005253_abnormal_eye_physiology1.21999038
48MP0003195_calcinosis1.20811965
49MP0002080_prenatal_lethality1.19522379
50MP0003011_delayed_dark_adaptation1.17141148
51MP0003941_abnormal_skin_development1.16808709
52MP0001697_abnormal_embryo_size1.16109026
53MP0002210_abnormal_sex_determination1.15140843
54MP0001853_heart_inflammation1.14397151
55MP0003937_abnormal_limbs/digits/tail_de1.13120078
56MP0002751_abnormal_autonomic_nervous1.09605800
57MP0003890_abnormal_embryonic-extraembry1.09545082
58MP0003880_abnormal_central_pattern1.08127465
59MP0000358_abnormal_cell_content/1.07906957
60MP0004808_abnormal_hematopoietic_stem1.07798775
61MP0003646_muscle_fatigue1.07705525
62MP0001188_hyperpigmentation1.06953878
63MP0002398_abnormal_bone_marrow1.06550050
64MP0001984_abnormal_olfaction1.05189306
65MP0005174_abnormal_tail_pigmentation1.05131729
66MP0002938_white_spotting1.04738885
67MP0005389_reproductive_system_phenotype1.03964550
68MP0002722_abnormal_immune_system1.03893331
69MP0005380_embryogenesis_phenotype1.03884444
70MP0001672_abnormal_embryogenesis/_devel1.03884444
71MP0005671_abnormal_response_to1.03882999
72MP0001145_abnormal_male_reproductive1.03737550
73MP0001545_abnormal_hematopoietic_system1.03498835
74MP0005397_hematopoietic_system_phenotyp1.03498835
75MP0010030_abnormal_orbit_morphology1.00295699
76MP0000689_abnormal_spleen_morphology1.00156090
77MP0002160_abnormal_reproductive_system0.99870740
78MP0005394_taste/olfaction_phenotype0.99299606
79MP0005499_abnormal_olfactory_system0.99299606
80MP0001905_abnormal_dopamine_level0.98780972
81MP0001929_abnormal_gametogenesis0.96466382
82MP0000653_abnormal_sex_gland0.94293356
83MP0000703_abnormal_thymus_morphology0.93608941
84MP0000015_abnormal_ear_pigmentation0.93478323
85MP0002090_abnormal_vision0.90472188
86MP0001968_abnormal_touch/_nociception0.90326424
87MP0002429_abnormal_blood_cell0.90264180
88MP0000631_abnormal_neuroendocrine_gland0.88905484
89MP0000566_synostosis0.88793525
90MP0000647_abnormal_sebaceous_gland0.87843036
91MP0003984_embryonic_growth_retardation0.87180113
92MP0001919_abnormal_reproductive_system0.86827931
93MP0005332_abnormal_amino_acid0.86141599
94MP0004142_abnormal_muscle_tone0.85544652
95MP0008872_abnormal_physiological_respon0.85030205
96MP0001485_abnormal_pinna_reflex0.84987728
97MP0002088_abnormal_embryonic_growth/wei0.82760715
98MP0003119_abnormal_digestive_system0.82223427
99MP0005266_abnormal_metabolism0.80603138
100MP0000049_abnormal_middle_ear0.80456633
101MP0002233_abnormal_nose_morphology0.80320368
102MP0003698_abnormal_male_reproductive0.79681861
103MP0001119_abnormal_female_reproductive0.78584474
104MP0003136_yellow_coat_color0.78247563
105MP0002254_reproductive_system_inflammat0.77929089
106MP0003787_abnormal_imprinting0.77140680
107MP0002085_abnormal_embryonic_tissue0.75496030
108MP0000716_abnormal_immune_system0.75000353
109MP0003656_abnormal_erythrocyte_physiolo0.74657545
110MP0001324_abnormal_eye_pigmentation0.74076165
111MP0005636_abnormal_mineral_homeostasis0.73355420
112MP0009046_muscle_twitch0.73221384
113MP0004782_abnormal_surfactant_physiolog0.73120068
114MP0004145_abnormal_muscle_electrophysio0.72842482
115MP0001286_abnormal_eye_development0.72526900
116MP0005408_hypopigmentation0.71577728
117MP0004215_abnormal_myocardial_fiber0.71192992
118MP0006276_abnormal_autonomic_nervous0.69194148
119MP0005360_urolithiasis0.68684698
120MP0005084_abnormal_gallbladder_morpholo0.67931826
121MP0002638_abnormal_pupillary_reflex0.66756514
122MP0000465_gastrointestinal_hemorrhage0.65423238
123MP0003121_genomic_imprinting0.65086535
124MP0008995_early_reproductive_senescence0.64180571
125MP0005384_cellular_phenotype0.63647089
126MP0002086_abnormal_extraembryonic_tissu0.61548090
127MP0003866_abnormal_defecation0.60498631
128MP0002876_abnormal_thyroid_physiology0.60252206
129MP0002277_abnormal_respiratory_mucosa0.60236690
130MP0004381_abnormal_hair_follicle0.59480379
131MP0002163_abnormal_gland_morphology0.59424269
132MP0003221_abnormal_cardiomyocyte_apopto0.58173037
133MP0001542_abnormal_bone_strength0.57289065
134MP0002084_abnormal_developmental_patter0.57092123
135MP0005395_other_phenotype0.56349621
136MP0000372_irregular_coat_pigmentation0.56294099
137MP0001186_pigmentation_phenotype0.55499022
138MP0001835_abnormal_antigen_presentation0.54038721
139MP0002420_abnormal_adaptive_immunity0.52959554
140MP0001293_anophthalmia0.51937775
141MP0004133_heterotaxia0.51578148

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.64445415
2Abnormal number of erythroid precursors (HP:0012131)5.56883943
3Birth length less than 3rd percentile (HP:0003561)5.09679144
4Hepatocellular necrosis (HP:0001404)4.02588354
5Reticulocytopenia (HP:0001896)4.02047120
6Mitochondrial inheritance (HP:0001427)3.89664949
7Acute necrotizing encephalopathy (HP:0006965)3.84303659
8Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.76063788
9Hepatic necrosis (HP:0002605)3.70151070
10Macrocytic anemia (HP:0001972)3.65426001
11Breast hypoplasia (HP:0003187)3.63524164
12Increased CSF lactate (HP:0002490)3.63325659
13Aplastic anemia (HP:0001915)3.61160266
14Decreased activity of mitochondrial respiratory chain (HP:0008972)3.57486295
15Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.57486295
16Abnormal mitochondria in muscle tissue (HP:0008316)3.57032945
17Type I transferrin isoform profile (HP:0003642)3.54033301
18Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.51135055
19Cerebral hypomyelination (HP:0006808)3.49904198
20Increased hepatocellular lipid droplets (HP:0006565)3.48135660
21Oral leukoplakia (HP:0002745)3.47635746
22Increased serum lactate (HP:0002151)3.42961809
23Acute encephalopathy (HP:0006846)3.26175613
24Rough bone trabeculation (HP:0100670)3.22260706
253-Methylglutaconic aciduria (HP:0003535)3.22129655
26Pallor (HP:0000980)3.14950740
27Lipid accumulation in hepatocytes (HP:0006561)3.12121213
28Abnormality of the labia minora (HP:0012880)2.97104261
29Microretrognathia (HP:0000308)2.90213213
30Progressive macrocephaly (HP:0004481)2.89286441
31Methylmalonic aciduria (HP:0012120)2.82034630
32Lactic acidosis (HP:0003128)2.80467531
33Methylmalonic acidemia (HP:0002912)2.77125058
34Carpal bone hypoplasia (HP:0001498)2.74729033
35Renal Fanconi syndrome (HP:0001994)2.74336036
36Reduced antithrombin III activity (HP:0001976)2.73330668
37Microvesicular hepatic steatosis (HP:0001414)2.68467384
38Increased intramyocellular lipid droplets (HP:0012240)2.65408856
39Exercise intolerance (HP:0003546)2.63136039
40CNS hypomyelination (HP:0003429)2.62833155
41Progressive muscle weakness (HP:0003323)2.59611114
42Exertional dyspnea (HP:0002875)2.59395026
43Patellar aplasia (HP:0006443)2.55685088
44Abnormality of the heme biosynthetic pathway (HP:0010472)2.52850922
45Pancreatic cysts (HP:0001737)2.51571444
46Abnormality of the preputium (HP:0100587)2.51011490
47Aplasia/Hypoplasia of the sacrum (HP:0008517)2.48755180
48Respiratory difficulties (HP:0002880)2.48709007
49Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.48561251
50Abnormal protein N-linked glycosylation (HP:0012347)2.48561251
51Abnormal protein glycosylation (HP:0012346)2.48561251
52Abnormal glycosylation (HP:0012345)2.48561251
53Type 2 muscle fiber atrophy (HP:0003554)2.44699315
54Abnormal trabecular bone morphology (HP:0100671)2.44212707
55Optic disc pallor (HP:0000543)2.43471599
56Premature graying of hair (HP:0002216)2.41801121
57Aplasia/Hypoplasia of the patella (HP:0006498)2.40754607
58Abnormality of glycolysis (HP:0004366)2.39022104
59Increased serum pyruvate (HP:0003542)2.39022104
60Respiratory failure (HP:0002878)2.38504363
61Abnormality of methionine metabolism (HP:0010901)2.38069033
62Leukodystrophy (HP:0002415)2.37129449
63Muscle fiber atrophy (HP:0100295)2.36546279
64CNS demyelination (HP:0007305)2.36535058
65Pancytopenia (HP:0001876)2.35388999
66Abnormality of serum amino acid levels (HP:0003112)2.35340079
67Abnormality of aspartate family amino acid metabolism (HP:0010899)2.34200177
68Abnormality of midbrain morphology (HP:0002418)2.31977363
69Molar tooth sign on MRI (HP:0002419)2.31977363
70Abnormality of the anterior horn cell (HP:0006802)2.31402402
71Degeneration of anterior horn cells (HP:0002398)2.31402402
72Lethargy (HP:0001254)2.30846253
73Colon cancer (HP:0003003)2.29334687
74Megaloblastic anemia (HP:0001889)2.28471210
75Hyperglycinemia (HP:0002154)2.28470491
76Bone marrow hypocellularity (HP:0005528)2.27202109
77Sparse eyelashes (HP:0000653)2.24620855
78Meckel diverticulum (HP:0002245)2.22741529
79Secondary amenorrhea (HP:0000869)2.21417613
80Cellular immunodeficiency (HP:0005374)2.20940799
81Chromsome breakage (HP:0040012)2.20172613
82Increased muscle lipid content (HP:0009058)2.20134066
83Emotional lability (HP:0000712)2.17885988
84Aplasia/hypoplasia of the uterus (HP:0008684)2.16799294
85Abnormality of the ileum (HP:0001549)2.15647522
86Cerebral edema (HP:0002181)2.14657404
87Premature ovarian failure (HP:0008209)2.12329601
88Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.11309004
89Abnormality of alanine metabolism (HP:0010916)2.11309004
90Hyperalaninemia (HP:0003348)2.11309004
91True hermaphroditism (HP:0010459)2.10865705
92Absent thumb (HP:0009777)2.08605699
93Chromosomal breakage induced by crosslinking agents (HP:0003221)2.07346235
94Thrombocytosis (HP:0001894)2.06114141
95Selective tooth agenesis (HP:0001592)2.03730802
9611 pairs of ribs (HP:0000878)2.02842065
97IgM deficiency (HP:0002850)2.01022012
98Myelodysplasia (HP:0002863)2.00467645
99Horseshoe kidney (HP:0000085)1.99299016
100Abnormality of chromosome stability (HP:0003220)1.94297206
101Abnormal lung lobation (HP:0002101)1.92413681
102Abnormality of the duodenum (HP:0002246)1.91421117
103Triphalangeal thumb (HP:0001199)1.90449253
104Supernumerary spleens (HP:0009799)1.87868672
105Postnatal microcephaly (HP:0005484)1.87394261
106Hypoplasia of the pons (HP:0012110)1.87391544
107Cleft eyelid (HP:0000625)1.87298504
108Unsteady gait (HP:0002317)1.87157965
109Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.86655217
110Abnormal spermatogenesis (HP:0008669)1.86635579
111Abnormality of glycine metabolism (HP:0010895)1.86300010
112Abnormality of serine family amino acid metabolism (HP:0010894)1.86300010
113Hyperglycinuria (HP:0003108)1.86093059
114Abnormality of urine glucose concentration (HP:0011016)1.84520738
115Glycosuria (HP:0003076)1.84520738
116Homocystinuria (HP:0002156)1.84436364
117Abnormality of homocysteine metabolism (HP:0010919)1.84436364
118Abnormality of the pons (HP:0007361)1.83283033
119Multiple enchondromatosis (HP:0005701)1.83137251
120Abnormality of renal resorption (HP:0011038)1.81761220
121Impulsivity (HP:0100710)1.81411636
122Nephronophthisis (HP:0000090)1.81408312
123Petechiae (HP:0000967)1.81251965
124Congenital, generalized hypertrichosis (HP:0004540)1.80177730
125Medial flaring of the eyebrow (HP:0010747)1.80080345
126Small intestinal stenosis (HP:0012848)1.79279849
127Duodenal stenosis (HP:0100867)1.79279849
128Pancreatic fibrosis (HP:0100732)1.79164900
129Aplasia/Hypoplasia of the uvula (HP:0010293)1.78898667
130Generalized aminoaciduria (HP:0002909)1.78845038
131Sloping forehead (HP:0000340)1.77061790
132Abnormal biliary tract physiology (HP:0012439)1.76477731
133Bile duct proliferation (HP:0001408)1.76477731
134Pendular nystagmus (HP:0012043)1.75745108

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.03596711
2WEE14.41628260
3STK163.77301485
4VRK23.75716591
5EIF2AK13.27213841
6NME23.11864816
7TSSK63.03853430
8SRPK12.99868848
9VRK12.63204246
10PLK42.53702401
11CDC72.52425582
12EIF2AK32.49468995
13NUAK12.32791532
14ACVR1B2.27819113
15BRSK22.20378276
16CCNB11.98396474
17MAP4K21.93058044
18NME11.84196039
19TRIM281.72233666
20WNK31.71241648
21PLK11.66591058
22MKNK11.65808491
23DYRK31.62226635
24ZAK1.59608643
25TTK1.51512304
26TAOK31.46811041
27IRAK31.45644614
28PDK21.43787647
29PLK31.42439904
30PIM21.41891044
31TLK11.41191074
32MKNK21.40785412
33NEK21.40569751
34NEK11.39865141
35PASK1.35526164
36KDR1.34777045
37AURKB1.34135289
38BRSK11.30891345
39TAF11.27018206
40ATR1.18625228
41AURKA1.16212588
42CDK71.15700600
43FRK1.12284421
44MUSK1.10562922
45EIF2AK21.06406137
46PNCK1.05914560
47EPHA21.04722051
48RPS6KB21.02775888
49BCKDK1.02302192
50TEC0.99853607
51IRAK40.99273291
52CHEK20.96533164
53MAP3K120.95296985
54CDK80.93486483
55CDK190.91589593
56TGFBR10.87960513
57TESK20.86819307
58BRAF0.86632785
59CSNK1G10.82089885
60MST40.81323796
61OXSR10.79447001
62CSNK2A10.79233108
63CSNK2A20.78049462
64PBK0.72760441
65WNK40.71738214
66PLK20.71490409
67TIE10.70503698
68MAP3K40.68735855
69FLT30.65411397
70CSNK1G20.65287854
71BMPR1B0.63504588
72STK30.63214898
73MAP3K80.63011636
74CHEK10.62713732
75INSRR0.59479294
76DAPK10.59212534
77PINK10.58801779
78DYRK20.57972674
79PRKCI0.57531748
80MYLK0.54791982
81PIM10.54723742
82CSNK1A1L0.54355410
83RPS6KA40.53606797
84RPS6KA50.52955673
85CASK0.52858578
86BTK0.52530644
87TXK0.52251866
88ERBB30.51037437
89CDK40.49249945
90ARAF0.49170539
91PAK40.48439650
92STK390.47535749
93BCR0.47454269
94LIMK10.47247624
95AKT30.46867077
96MAP2K60.45830964
97ALK0.45500334
98ATM0.44558886
99CDK20.44184282
100CSNK1G30.43919971
101PRKCG0.43419639
102MAP4K10.42870716
103KIT0.41887032
104ILK0.41028790
105STK240.40732053
106PAK10.39985993
107STK40.38929521
108PDK30.38282621
109PDK40.38282621
110MAP3K110.36885909
111MAP2K70.35770264
112CAMKK20.35189537
113ADRBK20.34930946
114TNIK0.34457651
115PIK3CG0.34145948
116ABL20.32513350
117ZAP700.32455788
118CDK10.31567407
119STK38L0.30827229
120PHKG10.30504368
121PHKG20.30504368
122FGFR10.29954355
123YES10.28984701
124MAP2K30.28890703
125GRK10.28346651
126SCYL20.28337416
127MAPKAPK50.27078228
128LYN0.26975594
129CSNK1E0.23760296
130SYK0.22899403

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.61288983
2Ribosome_Homo sapiens_hsa030104.52372825
3DNA replication_Homo sapiens_hsa030304.44397099
4RNA polymerase_Homo sapiens_hsa030204.14582682
5Mismatch repair_Homo sapiens_hsa034303.62129359
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.46443791
7Spliceosome_Homo sapiens_hsa030402.93515114
8Pyrimidine metabolism_Homo sapiens_hsa002402.84075513
9Homologous recombination_Homo sapiens_hsa034402.77955609
10Nucleotide excision repair_Homo sapiens_hsa034202.63130284
11Base excision repair_Homo sapiens_hsa034102.56231125
12RNA transport_Homo sapiens_hsa030132.50604368
13Oxidative phosphorylation_Homo sapiens_hsa001902.14022461
14Protein export_Homo sapiens_hsa030602.07851272
15Parkinsons disease_Homo sapiens_hsa050122.01295086
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.98243969
17Cell cycle_Homo sapiens_hsa041101.92775365
18Basal transcription factors_Homo sapiens_hsa030221.91914215
19Non-homologous end-joining_Homo sapiens_hsa034501.86388141
20Fanconi anemia pathway_Homo sapiens_hsa034601.81222031
21One carbon pool by folate_Homo sapiens_hsa006701.76409023
22Folate biosynthesis_Homo sapiens_hsa007901.74052039
23Purine metabolism_Homo sapiens_hsa002301.72406842
24* RNA degradation_Homo sapiens_hsa030181.66079699
25Huntingtons disease_Homo sapiens_hsa050161.62562522
26Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.57499823
27Vitamin B6 metabolism_Homo sapiens_hsa007501.51278472
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.45675801
29Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.41273542
30Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.19693272
31Cysteine and methionine metabolism_Homo sapiens_hsa002701.18227512
32Alzheimers disease_Homo sapiens_hsa050101.17890956
33Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.07020582
34Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.02590580
35Pentose phosphate pathway_Homo sapiens_hsa000300.98876032
36Epstein-Barr virus infection_Homo sapiens_hsa051690.97688536
37p53 signaling pathway_Homo sapiens_hsa041150.96804066
38Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.95409832
39Drug metabolism - other enzymes_Homo sapiens_hsa009830.94331342
40Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.92340111
41Sulfur relay system_Homo sapiens_hsa041220.88952299
42Butanoate metabolism_Homo sapiens_hsa006500.88796183
43Steroid biosynthesis_Homo sapiens_hsa001000.87881854
44mRNA surveillance pathway_Homo sapiens_hsa030150.84936091
45Sulfur metabolism_Homo sapiens_hsa009200.81977694
46Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.80709539
47Phototransduction_Homo sapiens_hsa047440.79585994
48Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.78097447
49Biosynthesis of amino acids_Homo sapiens_hsa012300.75621197
50Fructose and mannose metabolism_Homo sapiens_hsa000510.69865512
51Glutathione metabolism_Homo sapiens_hsa004800.69607167
52Metabolic pathways_Homo sapiens_hsa011000.67804171
53Regulation of autophagy_Homo sapiens_hsa041400.67670241
54Cyanoamino acid metabolism_Homo sapiens_hsa004600.66077350
55Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.65913656
56Antigen processing and presentation_Homo sapiens_hsa046120.60692759
57Carbon metabolism_Homo sapiens_hsa012000.60556228
58Nitrogen metabolism_Homo sapiens_hsa009100.60512604
59Selenocompound metabolism_Homo sapiens_hsa004500.59513178
60Systemic lupus erythematosus_Homo sapiens_hsa053220.58715600
61Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.56917605
62Primary immunodeficiency_Homo sapiens_hsa053400.55428243
63N-Glycan biosynthesis_Homo sapiens_hsa005100.54147542
64Oocyte meiosis_Homo sapiens_hsa041140.51284674
652-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.49879376
66Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.49173435
67Herpes simplex infection_Homo sapiens_hsa051680.48088882
68Tryptophan metabolism_Homo sapiens_hsa003800.47995289
69Arachidonic acid metabolism_Homo sapiens_hsa005900.47789388
70Pentose and glucuronate interconversions_Homo sapiens_hsa000400.46548742
71Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.46127396
72Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.46113744
73Fatty acid metabolism_Homo sapiens_hsa012120.43098066
74Caffeine metabolism_Homo sapiens_hsa002320.42125033
75SNARE interactions in vesicular transport_Homo sapiens_hsa041300.40215315
76Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.39870384
77Fatty acid degradation_Homo sapiens_hsa000710.39237970
78Collecting duct acid secretion_Homo sapiens_hsa049660.39003320
79Pyruvate metabolism_Homo sapiens_hsa006200.37131551
80Fatty acid elongation_Homo sapiens_hsa000620.36005665
81Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.34791398
82Linoleic acid metabolism_Homo sapiens_hsa005910.34538538
83Chemical carcinogenesis_Homo sapiens_hsa052040.34131458
84Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.32953246
85Primary bile acid biosynthesis_Homo sapiens_hsa001200.32665879
86Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.31524974
87Galactose metabolism_Homo sapiens_hsa000520.31084556
88Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.30574167
89Cardiac muscle contraction_Homo sapiens_hsa042600.28126045
90Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.27420318
91Viral carcinogenesis_Homo sapiens_hsa052030.26782292
92Maturity onset diabetes of the young_Homo sapiens_hsa049500.25033972
93Olfactory transduction_Homo sapiens_hsa047400.24859572
94Arginine and proline metabolism_Homo sapiens_hsa003300.24592064
95Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.23745791
96Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.23032203
97Vitamin digestion and absorption_Homo sapiens_hsa049770.22993047
98Ether lipid metabolism_Homo sapiens_hsa005650.20406181
99Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.19868946
100Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.16593117
101Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.16423086
102Propanoate metabolism_Homo sapiens_hsa006400.14284579
103alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.14150648
104HTLV-I infection_Homo sapiens_hsa051660.13861846
105Legionellosis_Homo sapiens_hsa051340.13838059
106Thyroid cancer_Homo sapiens_hsa052160.12981122
107beta-Alanine metabolism_Homo sapiens_hsa004100.11202561
108Peroxisome_Homo sapiens_hsa041460.10543006
109Intestinal immune network for IgA production_Homo sapiens_hsa046720.09965284
110Alcoholism_Homo sapiens_hsa050340.09332470
111Phenylalanine metabolism_Homo sapiens_hsa003600.09167644
112Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.09159598
113Tyrosine metabolism_Homo sapiens_hsa003500.08937045
114Hematopoietic cell lineage_Homo sapiens_hsa046400.07630942
115Glycerophospholipid metabolism_Homo sapiens_hsa005640.06947070
116Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.05819653
117Renin-angiotensin system_Homo sapiens_hsa046140.05099379
118Sphingolipid metabolism_Homo sapiens_hsa006000.04883397
119Retinol metabolism_Homo sapiens_hsa008300.02525536
120Measles_Homo sapiens_hsa051620.00796762
121Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.00707709
122Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.00380137
123RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622-0.0043203

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