EXOSC5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.40555504
2DNA strand elongation involved in DNA replication (GO:0006271)4.81631579
3* DNA deamination (GO:0045006)4.80002806
4telomere maintenance via semi-conservative replication (GO:0032201)4.78520152
5DNA strand elongation (GO:0022616)4.62024466
6chaperone-mediated protein transport (GO:0072321)4.61124666
7viral transcription (GO:0019083)4.57115447
8mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.52024486
9translational termination (GO:0006415)4.45921534
10maturation of SSU-rRNA (GO:0030490)4.44377348
11ribosomal small subunit biogenesis (GO:0042274)4.37842769
12DNA replication initiation (GO:0006270)4.22607209
13telomere maintenance via recombination (GO:0000722)4.21479255
14establishment of protein localization to mitochondrial membrane (GO:0090151)4.15418127
15translational elongation (GO:0006414)4.13442165
16regulation of mitochondrial translation (GO:0070129)4.12315068
17ribosomal large subunit biogenesis (GO:0042273)4.09286098
18nucleobase biosynthetic process (GO:0046112)4.05366510
19energy coupled proton transport, down electrochemical gradient (GO:0015985)4.04852382
20ATP synthesis coupled proton transport (GO:0015986)4.04852382
21regulation of cellular amino acid metabolic process (GO:0006521)3.95052340
22formation of translation preinitiation complex (GO:0001731)3.94265976
23base-excision repair, AP site formation (GO:0006285)3.93267066
24SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.91483452
25ribonucleoprotein complex biogenesis (GO:0022613)3.90044906
26protein targeting to mitochondrion (GO:0006626)3.89397073
27purine nucleobase biosynthetic process (GO:0009113)3.88823129
28pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.84765888
29mitotic recombination (GO:0006312)3.82420432
30cotranslational protein targeting to membrane (GO:0006613)3.80247260
31translational initiation (GO:0006413)3.79356048
32signal transduction involved in DNA damage checkpoint (GO:0072422)3.79095958
33signal transduction involved in DNA integrity checkpoint (GO:0072401)3.79095958
34protein targeting to ER (GO:0045047)3.78636133
35telomere maintenance via telomere lengthening (GO:0010833)3.74424196
36ribosome biogenesis (GO:0042254)3.72826558
37signal transduction involved in cell cycle checkpoint (GO:0072395)3.72338627
38mitochondrial respiratory chain complex assembly (GO:0033108)3.70503222
39cullin deneddylation (GO:0010388)3.68025953
40positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.66281996
41nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.65800476
42protein deneddylation (GO:0000338)3.64783923
43protein complex biogenesis (GO:0070271)3.64363614
44DNA replication checkpoint (GO:0000076)3.63612371
45DNA unwinding involved in DNA replication (GO:0006268)3.59597287
46protein localization to endoplasmic reticulum (GO:0070972)3.58949639
47pseudouridine synthesis (GO:0001522)3.58604702
48mitochondrial respiratory chain complex I assembly (GO:0032981)3.58477280
49NADH dehydrogenase complex assembly (GO:0010257)3.58477280
50mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.58477280
51establishment of protein localization to mitochondrion (GO:0072655)3.57923590
52deoxyribonucleotide catabolic process (GO:0009264)3.57426132
53purine deoxyribonucleotide catabolic process (GO:0009155)3.57368494
54establishment of protein localization to endoplasmic reticulum (GO:0072599)3.56941466
55deoxyribose phosphate catabolic process (GO:0046386)3.55535809
56cellular protein complex disassembly (GO:0043624)3.53103334
57mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.51369586
58nucleotide-excision repair, DNA gap filling (GO:0006297)3.51258119
59positive regulation of ligase activity (GO:0051351)3.50237463
60respiratory electron transport chain (GO:0022904)3.49430695
61protein localization to mitochondrion (GO:0070585)3.46051404
62viral life cycle (GO:0019058)3.45774599
63respiratory chain complex IV assembly (GO:0008535)3.45750011
64establishment of viral latency (GO:0019043)3.44880521
65* rRNA processing (GO:0006364)3.43388179
66IMP biosynthetic process (GO:0006188)3.42652917
67tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.40643459
68RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.40643459
69spliceosomal snRNP assembly (GO:0000387)3.40631534
70electron transport chain (GO:0022900)3.40335454
71pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.38341250
72chromatin remodeling at centromere (GO:0031055)3.38158184
73deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.38047676
74oxidative phosphorylation (GO:0006119)3.35503575
75* rRNA metabolic process (GO:0016072)3.33082738
76proteasome assembly (GO:0043248)3.31802949
77CENP-A containing nucleosome assembly (GO:0034080)3.31586418
78deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.31233701
79peptidyl-histidine modification (GO:0018202)3.31226867
80regulation of ubiquitin-protein transferase activity (GO:0051438)3.28800787
81folic acid-containing compound biosynthetic process (GO:0009396)3.26146591
82pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.25582117
83pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.24923185
84maturation of 5.8S rRNA (GO:0000460)3.24746771
85rRNA methylation (GO:0031167)3.24658728
86protein complex disassembly (GO:0043241)3.24406204
87rRNA modification (GO:0000154)3.23062652
88cytochrome complex assembly (GO:0017004)3.22526247
89translation (GO:0006412)3.22061339
90mitochondrial RNA metabolic process (GO:0000959)3.20583310
91regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.19465015
92antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.17743610
93regulation of ligase activity (GO:0051340)3.16906895
94negative regulation of B cell apoptotic process (GO:0002903)3.15866738
95transcription-coupled nucleotide-excision repair (GO:0006283)3.15195332
96guanosine-containing compound biosynthetic process (GO:1901070)3.14565938
97mitotic metaphase plate congression (GO:0007080)3.12106141
98protein localization to kinetochore (GO:0034501)3.09276349
99DNA replication-dependent nucleosome assembly (GO:0006335)3.08419917
100DNA replication-dependent nucleosome organization (GO:0034723)3.08419917
101ribosome assembly (GO:0042255)3.07576910
102macromolecular complex disassembly (GO:0032984)3.06752365
103cellular component biogenesis (GO:0044085)3.03573039
104IMP metabolic process (GO:0046040)3.02421342
105protein localization to chromosome, centromeric region (GO:0071459)3.00925324
106DNA replication-independent nucleosome organization (GO:0034724)2.97102844
107DNA replication-independent nucleosome assembly (GO:0006336)2.97102844
108* nuclear-transcribed mRNA catabolic process (GO:0000956)2.97014181
109mitotic nuclear envelope disassembly (GO:0007077)2.95027972
110telomere organization (GO:0032200)2.94877415
111pteridine-containing compound biosynthetic process (GO:0042559)2.94193880
112telomere maintenance (GO:0000723)2.94046977
113regulation of nuclear cell cycle DNA replication (GO:0033262)2.93618983
114transcription elongation from RNA polymerase III promoter (GO:0006385)2.93336997
115termination of RNA polymerase III transcription (GO:0006386)2.93336997
116negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.92648199
117histone exchange (GO:0043486)2.86552722
118establishment of integrated proviral latency (GO:0075713)2.86483450
119regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.85289931
120kinetochore assembly (GO:0051382)2.84604443
121anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.83471257
122* exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.83365526
123kinetochore organization (GO:0051383)2.83359068
124* mRNA catabolic process (GO:0006402)2.82914957
125* RNA catabolic process (GO:0006401)2.82062535
126positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.77738079
127tRNA methylation (GO:0030488)2.76931279
128viral mRNA export from host cell nucleus (GO:0046784)2.74806407
129* nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.72832688
130negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.72293318
131negative regulation of ligase activity (GO:0051352)2.72293318
132* ncRNA processing (GO:0034470)2.71105621
133DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.70635092
134G1/S transition of mitotic cell cycle (GO:0000082)2.70406757
135cell cycle G1/S phase transition (GO:0044843)2.70406757
136* ncRNA metabolic process (GO:0034660)2.70102331
137folic acid metabolic process (GO:0046655)2.69472297
138signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.69146490
139signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.69146490
140signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.69146490
141metaphase plate congression (GO:0051310)2.69045228
142intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.68688197
143signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.68688197
144spliceosomal complex assembly (GO:0000245)2.68313059
145termination of RNA polymerase II transcription (GO:0006369)2.68252399
146termination of RNA polymerase I transcription (GO:0006363)2.68012003
147regulation of double-strand break repair via homologous recombination (GO:0010569)2.67931908
148DNA-templated transcription, termination (GO:0006353)2.64487244
149base-excision repair (GO:0006284)2.64378430

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.02117622
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.11952305
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.67694734
4* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.03854283
5* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.00726732
6EST1_17652178_ChIP-ChIP_JURKAT_Human2.93834178
7* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.93383174
8E2F4_17652178_ChIP-ChIP_JURKAT_Human2.90667114
9ETS1_20019798_ChIP-Seq_JURKAT_Human2.82150170
10GABP_17652178_ChIP-ChIP_JURKAT_Human2.79724814
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.78937692
12* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.71497588
13NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.65810405
14FOXM1_23109430_ChIP-Seq_U2OS_Human2.64755273
15* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.60570298
16MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.49340771
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.49166319
18ELF1_17652178_ChIP-ChIP_JURKAT_Human2.48441963
19CREB1_15753290_ChIP-ChIP_HEK293T_Human2.38179689
20XRN2_22483619_ChIP-Seq_HELA_Human2.28215436
21* VDR_23849224_ChIP-Seq_CD4+_Human2.23940809
22SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.13155019
23CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.11883941
24NELFA_20434984_ChIP-Seq_ESCs_Mouse2.06933654
25SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.05808295
26* FOXP3_21729870_ChIP-Seq_TREG_Human1.99767508
27* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.96085201
28DCP1A_22483619_ChIP-Seq_HELA_Human1.89902603
29TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.89511353
30HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.87568104
31* GABP_19822575_ChIP-Seq_HepG2_Human1.85999592
32YY1_21170310_ChIP-Seq_MESCs_Mouse1.78628784
33THAP11_20581084_ChIP-Seq_MESCs_Mouse1.74453888
34FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.72945631
35* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.72838163
36TTF2_22483619_ChIP-Seq_HELA_Human1.69825566
37CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.69657337
38* POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.66798549
39NANOG_18555785_ChIP-Seq_MESCs_Mouse1.65290295
40MYCN_18555785_ChIP-Seq_MESCs_Mouse1.65226260
41E2F1_21310950_ChIP-Seq_MCF-7_Human1.63826413
42E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.62538287
43* SRF_21415370_ChIP-Seq_HL-1_Mouse1.62311551
44CIITA_25753668_ChIP-Seq_RAJI_Human1.57956079
45MYC_22102868_ChIP-Seq_BL_Human1.54736055
46* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.54456212
47FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.53471427
48HOXB4_20404135_ChIP-ChIP_EML_Mouse1.51106882
49PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50747546
50* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.48967030
51* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.45760167
52SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.43030322
53NOTCH1_21737748_ChIP-Seq_TLL_Human1.42519782
54MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.42295038
55AR_21909140_ChIP-Seq_LNCAP_Human1.41415829
56ZFX_18555785_ChIP-Seq_MESCs_Mouse1.39685328
57KDM5A_27292631_Chip-Seq_BREAST_Human1.37041994
58ELK1_19687146_ChIP-ChIP_HELA_Human1.31612609
59VDR_21846776_ChIP-Seq_THP-1_Human1.27941166
60STAT3_1855785_ChIP-Seq_MESCs_Mouse1.27896287
61YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.27461622
62ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.26999696
63* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.22748557
64SPI1_23547873_ChIP-Seq_NB4_Human1.17278508
65IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.17182915
66SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.16248493
67* PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.15202870
68RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.14672655
69POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.13330905
70CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.11492044
71TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.10317470
72* POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.09015851
73BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.08068335
74CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.06200209
75GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.05962470
76E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.04245341
77* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.04239881
78EGR1_19374776_ChIP-ChIP_THP-1_Human1.03932652
79* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.03740957
80CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.03384682
81HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.02890630
82DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.02286644
83TFEB_21752829_ChIP-Seq_HELA_Human0.99355981
84TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.98557493
85ELK1_22589737_ChIP-Seq_MCF10A_Human0.97750890
86PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.96783168
87ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.95612034
88CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.94529064
89CTCF_18555785_ChIP-Seq_MESCs_Mouse0.92490717
90HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.92190357
91* KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.91526543
92CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.91358689
93SCL_19346495_ChIP-Seq_HPC-7_Human0.91261276
94MYC_18940864_ChIP-ChIP_HL60_Human0.90919689
95* FOXP1_21924763_ChIP-Seq_HESCs_Human0.90672187
96* PADI4_21655091_ChIP-ChIP_MCF-7_Human0.87974163
97* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.87173059
98* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.87001051
99SOX2_18555785_ChIP-Seq_MESCs_Mouse0.86229763
100GATA1_22383799_ChIP-Seq_G1ME_Mouse0.86226300
101* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.85830397
102SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.84519689
103ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.84328116
104MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.83688217
105KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.83121131
106SRY_22984422_ChIP-ChIP_TESTIS_Rat0.82589244
107IRF8_22096565_ChIP-ChIP_GC-B_Human0.81994366
108YY1_22570637_ChIP-Seq_MALME-3M_Human0.80120979
109TP63_19390658_ChIP-ChIP_HaCaT_Human0.79565785
110ESR1_15608294_ChIP-ChIP_MCF-7_Human0.74253543
111TBX5_21415370_ChIP-Seq_HL-1_Mouse0.73513172
112ELF1_20517297_ChIP-Seq_JURKAT_Human0.71124100
113EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.70343032
114TET1_21451524_ChIP-Seq_MESCs_Mouse0.67199548
115CTCF_26484167_Chip-Seq_Bcells_Mouse0.66636428
116* NANOG_16153702_ChIP-ChIP_HESCs_Human0.66498922

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.09121070
2MP0010094_abnormal_chromosome_stability4.13410495
3MP0003111_abnormal_nucleus_morphology3.96584113
4MP0004957_abnormal_blastocyst_morpholog3.87599866
5MP0008057_abnormal_DNA_replication3.86318937
6MP0008058_abnormal_DNA_repair3.48743821
7MP0003077_abnormal_cell_cycle3.47382553
8MP0002396_abnormal_hematopoietic_system2.90755720
9MP0008007_abnormal_cellular_replicative2.67276293
10MP0003806_abnormal_nucleotide_metabolis2.54707063
11MP0000372_irregular_coat_pigmentation2.25367616
12MP0003786_premature_aging2.10366457
13MP0008932_abnormal_embryonic_tissue2.09428129
14MP0000490_abnormal_crypts_of2.01686565
15MP0003763_abnormal_thymus_physiology1.93456485
16MP0008877_abnormal_DNA_methylation1.91286527
17MP0005410_abnormal_fertilization1.91256850
18MP0001835_abnormal_antigen_presentation1.75573344
19MP0009333_abnormal_splenocyte_physiolog1.75230767
20MP0005397_hematopoietic_system_phenotyp1.74601708
21MP0001545_abnormal_hematopoietic_system1.74601708
22MP0001730_embryonic_growth_arrest1.73165950
23MP0003186_abnormal_redox_activity1.71253983
24MP0005075_abnormal_melanosome_morpholog1.68664789
25MP0004808_abnormal_hematopoietic_stem1.66180089
26MP0000350_abnormal_cell_proliferation1.66099090
27MP0003646_muscle_fatigue1.65799572
28MP0010352_gastrointestinal_tract_polyps1.59097472
29MP0002019_abnormal_tumor_incidence1.58513528
30MP0002398_abnormal_bone_marrow1.54711274
31MP0002837_dystrophic_cardiac_calcinosis1.54179637
32MP0001929_abnormal_gametogenesis1.52808091
33MP0000313_abnormal_cell_death1.50072847
34MP0002102_abnormal_ear_morphology1.49717917
35MP0002210_abnormal_sex_determination1.47189702
36MP0002132_abnormal_respiratory_system1.44851370
37MP0000689_abnormal_spleen_morphology1.44740707
38MP0002722_abnormal_immune_system1.42507030
39MP0005174_abnormal_tail_pigmentation1.40867915
40MP0010307_abnormal_tumor_latency1.40641273
41MP0001529_abnormal_vocalization1.37184033
42MP0003718_maternal_effect1.35818037
43MP0002736_abnormal_nociception_after1.33213064
44MP0001145_abnormal_male_reproductive1.30154681
45MP0001853_heart_inflammation1.29689561
46MP0008872_abnormal_physiological_respon1.28508603
47MP0005645_abnormal_hypothalamus_physiol1.27613523
48MP0000703_abnormal_thymus_morphology1.27605330
49MP0005646_abnormal_pituitary_gland1.26483794
50MP0002429_abnormal_blood_cell1.26192092
51MP0001986_abnormal_taste_sensitivity1.24670821
52MP0005671_abnormal_response_to1.24474308
53MP0000685_abnormal_immune_system1.23455540
54MP0000716_abnormal_immune_system1.20328902
55MP0006036_abnormal_mitochondrial_physio1.19753606
56MP0002080_prenatal_lethality1.19522178
57MP0001800_abnormal_humoral_immune1.18838079
58MP0001764_abnormal_homeostasis1.18091965
59MP0009379_abnormal_foot_pigmentation1.17932429
60MP0009785_altered_susceptibility_to1.17082620
61MP0002160_abnormal_reproductive_system1.16936736
62MP0006292_abnormal_olfactory_placode1.15737813
63MP0005380_embryogenesis_phenotype1.15269756
64MP0001672_abnormal_embryogenesis/_devel1.15269756
65MP0001697_abnormal_embryo_size1.13421904
66MP0003136_yellow_coat_color1.12506344
67MP0002420_abnormal_adaptive_immunity1.10008061
68MP0005025_abnormal_response_to1.09624800
69MP0002938_white_spotting1.09200215
70MP0000653_abnormal_sex_gland1.09053001
71MP0002163_abnormal_gland_morphology1.08260203
72MP0001819_abnormal_immune_cell1.08164784
73MP0008875_abnormal_xenobiotic_pharmacok1.08126695
74MP0005084_abnormal_gallbladder_morpholo1.06842540
75MP0000858_altered_metastatic_potential1.06076952
76MP0002723_abnormal_immune_serum1.05937282
77MP0003698_abnormal_male_reproductive1.05871807
78MP0002452_abnormal_antigen_presenting1.04155721
79MP0003123_paternal_imprinting1.03776959
80MP0000015_abnormal_ear_pigmentation1.01831625
81MP0003984_embryonic_growth_retardation1.00654292
82MP0000358_abnormal_cell_content/1.00097218
83MP0005464_abnormal_platelet_physiology0.98960040
84MP0002405_respiratory_system_inflammati0.97378100
85MP0002095_abnormal_skin_pigmentation0.97111802
86MP0002088_abnormal_embryonic_growth/wei0.95942265
87MP0002653_abnormal_ependyma_morphology0.94869826
88MP0001873_stomach_inflammation0.93566451
89MP0003436_decreased_susceptibility_to0.93095007
90MP0008789_abnormal_olfactory_epithelium0.92253987
91MP0005389_reproductive_system_phenotype0.91320548
92MP0008995_early_reproductive_senescence0.89972101
93MP0005330_cardiomyopathy0.89346224
94MP0008873_increased_physiological_sensi0.88479758
95MP0005000_abnormal_immune_tolerance0.86684665
96MP0001661_extended_life_span0.86558607
97MP0002086_abnormal_extraembryonic_tissu0.85904290
98MP0010155_abnormal_intestine_physiology0.85791504
99MP0002085_abnormal_embryonic_tissue0.85668860
100MP0000749_muscle_degeneration0.85652384
101MP0001293_anophthalmia0.85644593
102MP0002166_altered_tumor_susceptibility0.85357649
103MP0006035_abnormal_mitochondrial_morpho0.84110108
104MP0000465_gastrointestinal_hemorrhage0.83265091
105MP0002148_abnormal_hypersensitivity_rea0.83186651
106MP0006072_abnormal_retinal_apoptosis0.82859745
107MP0002006_tumorigenesis0.79938082
108MP0009697_abnormal_copulation0.79177334
109MP0001119_abnormal_female_reproductive0.78602169
110MP0003656_abnormal_erythrocyte_physiolo0.77954218
111MP0001968_abnormal_touch/_nociception0.76851970
112MP0005395_other_phenotype0.76573671
113MP0002138_abnormal_hepatobiliary_system0.76413507
114MP0005332_abnormal_amino_acid0.76106154
115MP0002277_abnormal_respiratory_mucosa0.74998241
116MP0002419_abnormal_innate_immunity0.74929375
117MP0008260_abnormal_autophagy0.74665557
118MP0004147_increased_porphyrin_level0.74465982
119MP0001881_abnormal_mammary_gland0.71436922
120MP0005266_abnormal_metabolism0.70941018
121MP0009278_abnormal_bone_marrow0.70596236
122MP0004133_heterotaxia0.70454930
123MP0001905_abnormal_dopamine_level0.69992647
124MP0002161_abnormal_fertility/fecundity0.69943202
125MP0005670_abnormal_white_adipose0.69436227
126MP0002084_abnormal_developmental_patter0.68702368
127MP0003315_abnormal_perineum_morphology0.66943094
128MP0001845_abnormal_inflammatory_respons0.66697689
129MP0001727_abnormal_embryo_implantation0.65439040
130MP0010030_abnormal_orbit_morphology0.63042175
131MP0009672_abnormal_birth_weight0.61058139
132MP0005220_abnormal_exocrine_pancreas0.60241188
133MP0005319_abnormal_enzyme/_coenzyme0.56895790
134MP0001188_hyperpigmentation0.55901287

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.50567408
2Abnormal number of erythroid precursors (HP:0012131)5.40235789
3Acute necrotizing encephalopathy (HP:0006965)5.16191294
4Abnormal mitochondria in muscle tissue (HP:0008316)5.05857135
5Reticulocytopenia (HP:0001896)4.90492428
6Mitochondrial inheritance (HP:0001427)4.84081642
7Acute encephalopathy (HP:0006846)4.73306893
8Increased CSF lactate (HP:0002490)4.61476886
9Hepatic necrosis (HP:0002605)4.52995265
10Aplastic anemia (HP:0001915)4.18947798
11Birth length less than 3rd percentile (HP:0003561)4.16789362
12Progressive macrocephaly (HP:0004481)4.10584007
13Oral leukoplakia (HP:0002745)3.73095691
14Cerebral edema (HP:0002181)3.61917256
15Macrocytic anemia (HP:0001972)3.52744752
16Lactic acidosis (HP:0003128)3.50706491
17Increased hepatocellular lipid droplets (HP:0006565)3.45952960
18Pallor (HP:0000980)3.37251795
19Breast hypoplasia (HP:0003187)3.36447363
20Increased intramyocellular lipid droplets (HP:0012240)3.35430956
21Thrombocytosis (HP:0001894)3.25615926
22Lipid accumulation in hepatocytes (HP:0006561)3.17394410
23Respiratory failure (HP:0002878)3.10696174
24Chromsome breakage (HP:0040012)3.09966987
25Exercise intolerance (HP:0003546)3.09938804
26Chromosomal breakage induced by crosslinking agents (HP:0003221)3.07357249
27IgM deficiency (HP:0002850)2.98456712
28Absent thumb (HP:0009777)2.92064674
29Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.91952984
30Decreased activity of mitochondrial respiratory chain (HP:0008972)2.91952984
31Type I transferrin isoform profile (HP:0003642)2.91855569
32Abnormality of the preputium (HP:0100587)2.88338776
33Pancytopenia (HP:0001876)2.84403736
34Increased muscle lipid content (HP:0009058)2.83372091
35Renal Fanconi syndrome (HP:0001994)2.83176005
3611 pairs of ribs (HP:0000878)2.82344829
37Carpal bone hypoplasia (HP:0001498)2.74744730
38Increased serum pyruvate (HP:0003542)2.73507745
39Selective tooth agenesis (HP:0001592)2.72890341
40Rough bone trabeculation (HP:0100670)2.72767433
41Abnormality of chromosome stability (HP:0003220)2.69987501
42Abnormality of the anterior horn cell (HP:0006802)2.68836940
43Degeneration of anterior horn cells (HP:0002398)2.68836940
44Testicular atrophy (HP:0000029)2.68282076
45Aplasia/Hypoplasia of the sacrum (HP:0008517)2.65764952
46Bone marrow hypocellularity (HP:0005528)2.64782491
47Meckel diverticulum (HP:0002245)2.64207517
48Microretrognathia (HP:0000308)2.62655027
49Abnormality of glycolysis (HP:0004366)2.62147477
50Myelodysplasia (HP:0002863)2.61663638
51Premature graying of hair (HP:0002216)2.57838786
52Abnormality of the ileum (HP:0001549)2.57714022
53Cerebral hypomyelination (HP:0006808)2.53626497
54Abnormality of pyrimidine metabolism (HP:0004353)2.53378695
55Patellar aplasia (HP:0006443)2.52679979
56Methylmalonic aciduria (HP:0012120)2.48140237
57Reduced antithrombin III activity (HP:0001976)2.47226824
58Lethargy (HP:0001254)2.43857937
59CNS demyelination (HP:0007305)2.43510052
60Opisthotonus (HP:0002179)2.41793207
61Abnormal spermatogenesis (HP:0008669)2.41770313
62Aplasia/Hypoplasia of the uvula (HP:0010293)2.41166221
63Progressive microcephaly (HP:0000253)2.40603993
64Colon cancer (HP:0003003)2.38583244
65Duplicated collecting system (HP:0000081)2.35710543
66Emotional lability (HP:0000712)2.32943003
67Leukodystrophy (HP:0002415)2.31334365
68Aplasia/Hypoplasia of the patella (HP:0006498)2.31205757
69Impulsivity (HP:0100710)2.31171774
70Recurrent bronchitis (HP:0002837)2.30152387
71Increased serum lactate (HP:0002151)2.29518762
72Lymphoma (HP:0002665)2.27858271
73Respiratory difficulties (HP:0002880)2.27746145
74Optic disc pallor (HP:0000543)2.26367502
75Dicarboxylic aciduria (HP:0003215)2.25253272
76Abnormality of dicarboxylic acid metabolism (HP:0010995)2.25253272
77Progressive muscle weakness (HP:0003323)2.20973608
78Multiple enchondromatosis (HP:0005701)2.20046230
79Agnosia (HP:0010524)2.19915369
80Acute lymphatic leukemia (HP:0006721)2.19392402
81Muscle fiber atrophy (HP:0100295)2.19275824
82Cellular immunodeficiency (HP:0005374)2.19227952
83Poikiloderma (HP:0001029)2.18899862
84Medulloblastoma (HP:0002885)2.17801950
85Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.16200528
86Abnormality of alanine metabolism (HP:0010916)2.16200528
87Hyperalaninemia (HP:0003348)2.16200528
88Abnormality of DNA repair (HP:0003254)2.15816095
89Trismus (HP:0000211)2.14418142
90Abnormal protein glycosylation (HP:0012346)2.14120646
91Abnormal glycosylation (HP:0012345)2.14120646
92Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.14120646
93Abnormal protein N-linked glycosylation (HP:0012347)2.14120646
94Exertional dyspnea (HP:0002875)2.13546212
95Type 2 muscle fiber atrophy (HP:0003554)2.13396369
96Hyperglycinemia (HP:0002154)2.12994073
97Ragged-red muscle fibers (HP:0003200)2.12892602
98Petechiae (HP:0000967)2.11189902
99Abnormality of the renal collecting system (HP:0004742)2.10873225
100Abnormality of the heme biosynthetic pathway (HP:0010472)2.10296503
101Abnormality of reticulocytes (HP:0004312)2.10226618
102Clubbing of toes (HP:0100760)2.06824976
103Abnormality of T cell physiology (HP:0011840)2.04807881
104Triphalangeal thumb (HP:0001199)2.04083030
1053-Methylglutaconic aciduria (HP:0003535)2.03464235
106Methylmalonic acidemia (HP:0002912)2.02608167
107Premature ovarian failure (HP:0008209)2.02358714
108Duodenal stenosis (HP:0100867)2.01827273
109Small intestinal stenosis (HP:0012848)2.01827273
110Decreased electroretinogram (ERG) amplitude (HP:0000654)2.01063179
111Sloping forehead (HP:0000340)1.99648949
112Abnormality of serum amino acid levels (HP:0003112)1.98453828
113Hypoplasia of the radius (HP:0002984)1.98101170
114Neoplasm of the pancreas (HP:0002894)1.97951086
115Hypoplasia of the pons (HP:0012110)1.97948537
116Horseshoe kidney (HP:0000085)1.96969318
117Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.96733170
118Supernumerary spleens (HP:0009799)1.95898475
119Absent radius (HP:0003974)1.95372028
120Abnormal trabecular bone morphology (HP:0100671)1.94823954
121Elevated erythrocyte sedimentation rate (HP:0003565)1.93197867
122Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.92660917
123Panhypogammaglobulinemia (HP:0003139)1.91845959
124Tracheoesophageal fistula (HP:0002575)1.91507373
125Microvesicular hepatic steatosis (HP:0001414)1.90545483
126Nasal polyposis (HP:0100582)1.90509420
127Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.90313621
128Abnormality of methionine metabolism (HP:0010901)1.90160573
129Cleft eyelid (HP:0000625)1.89538385
130Pulmonary fibrosis (HP:0002206)1.88663650
131Sparse eyelashes (HP:0000653)1.86644968
132Squamous cell carcinoma (HP:0002860)1.86344625
133Death in infancy (HP:0001522)1.85805598
134Abnormality of the pons (HP:0007361)1.85790930
135Bronchitis (HP:0012387)1.85381534
136Hepatocellular necrosis (HP:0001404)1.84076249
137Secondary amenorrhea (HP:0000869)1.83033459
138Poor head control (HP:0002421)1.82248046
139Abnormality of T cells (HP:0002843)1.81811366
140Megaloblastic anemia (HP:0001889)1.81397193
141Asplenia (HP:0001746)1.80680796
142Gliosis (HP:0002171)1.80334721
143Hyperglycinuria (HP:0003108)1.79853629
144Chronic otitis media (HP:0000389)1.79838979
145Leukopenia (HP:0001882)1.79180555
146Neoplasm of the adrenal gland (HP:0100631)1.78191094
147Generalized aminoaciduria (HP:0002909)1.78127280
148B lymphocytopenia (HP:0010976)1.78017379
149Abnormality of aspartate family amino acid metabolism (HP:0010899)1.77387723
150CNS hypomyelination (HP:0003429)1.74539765

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.71715779
2BUB14.13671745
3WEE13.89895016
4NME22.91692746
5STK162.80686216
6CDC72.80322188
7TESK22.51781034
8EIF2AK12.44088848
9NEK22.37647322
10PIM22.25259189
11SRPK12.14929399
12VRK12.14732778
13MAP4K12.10426400
14PLK42.10120818
15NUAK12.07111468
16ACVR1B1.93903798
17EIF2AK31.93613735
18NME11.85007975
19BCKDK1.83553774
20BRSK21.81847663
21TLK11.81716688
22TESK11.77160735
23PASK1.75160094
24MST41.71058038
25DYRK31.69017418
26TTK1.65248423
27CDK71.64819986
28ATR1.64594604
29PLK11.59955267
30RPS6KB21.58038798
31TSSK61.56925496
32TRIM281.49327463
33TAF11.47758652
34FLT31.46909850
35MAP4K21.35559751
36IRAK31.34374498
37AURKB1.28814845
38EEF2K1.27940786
39MAPKAPK31.19937196
40PIM11.19837455
41KDR1.19791206
42CSNK1G31.19156027
43BRSK11.18387110
44IRAK41.15116529
45MKNK11.14964702
46CCNB11.14458267
47ZAK1.13667202
48RPS6KA41.11320269
49NEK11.10493849
50CHEK21.10374331
51MAP3K111.07727227
52CDK41.07538785
53KIT1.06156826
54TEC1.04367125
55PDK41.03490827
56PDK31.03490827
57BTK1.03054057
58TGFBR11.02600162
59AURKA1.00952192
60SMG10.95928999
61SCYL20.95618966
62PAK40.93891035
63CSNK1G10.92845170
64MAP3K80.91174300
65STK100.90664302
66CSNK1A1L0.90202419
67EPHA20.87246059
68CDK80.86253002
69STK40.85100669
70CHEK10.84942184
71MAP2K30.83605282
72CSNK1G20.83093046
73MKNK20.83023299
74DYRK20.82977210
75ZAP700.80926331
76BLK0.80260627
77ARAF0.78990182
78TYK20.77637837
79TXK0.77389380
80BMPR1B0.75023923
81CSF1R0.74802771
82ABL20.73388087
83PLK30.72500009
84CSNK2A20.71994712
85CSNK2A10.71869319
86BRAF0.64908920
87WNK30.64813583
88MAP3K100.63751595
89EIF2AK20.63027828
90MAPKAPK50.62568765
91CLK10.62232249
92DAPK30.62082837
93PDK20.62002709
94PAK10.60383060
95IKBKB0.59397550
96RPS6KA50.59248909
97GRK60.59192318
98ATM0.57989564
99CDK20.57080982
100LRRK20.56080762
101JAK30.55397102
102PRKCI0.55023845
103LIMK10.51169487
104TAOK20.50857527
105MAPK110.50690110
106PKN20.43932352
107LYN0.42939375
108CDK120.42876203
109SYK0.41491699
110CDK190.41364591
111ERN10.38587384
112ALK0.38122918
113MUSK0.36759159
114GRK10.36437043
115MATK0.35536372
116TBK10.35018982
117IKBKE0.34682043
118AKT20.34476158
119TAOK30.34324679
120CDK90.32535226
121DAPK10.31835958
122CDK10.31339210
123YES10.31004967
124RPS6KA60.30809790
125MAP2K20.30039429
126MAP2K60.29018023
127PBK0.28625685
128SIK30.26257762
129CSNK1A10.23995751
130GRK50.23080447
131TNK20.20256860

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.97315315
2Ribosome_Homo sapiens_hsa030104.16462880
3Mismatch repair_Homo sapiens_hsa034304.01620930
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.19899432
5RNA polymerase_Homo sapiens_hsa030203.15455580
6Proteasome_Homo sapiens_hsa030503.13369533
7Base excision repair_Homo sapiens_hsa034103.08776631
8Homologous recombination_Homo sapiens_hsa034403.01650668
9Spliceosome_Homo sapiens_hsa030402.91018134
10Nucleotide excision repair_Homo sapiens_hsa034202.70232145
11Pyrimidine metabolism_Homo sapiens_hsa002402.67188704
12RNA transport_Homo sapiens_hsa030132.46364840
13One carbon pool by folate_Homo sapiens_hsa006702.45295809
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.20717914
15Fanconi anemia pathway_Homo sapiens_hsa034602.18962002
16Cell cycle_Homo sapiens_hsa041101.93688586
17Non-homologous end-joining_Homo sapiens_hsa034501.86630784
18Basal transcription factors_Homo sapiens_hsa030221.77129098
19Alzheimers disease_Homo sapiens_hsa050101.62147313
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.57920596
21* RNA degradation_Homo sapiens_hsa030181.54631979
22Purine metabolism_Homo sapiens_hsa002301.44629823
23Fatty acid elongation_Homo sapiens_hsa000621.43323092
24Folate biosynthesis_Homo sapiens_hsa007901.40469861
25Pentose phosphate pathway_Homo sapiens_hsa000301.36444393
26Sulfur relay system_Homo sapiens_hsa041221.29646233
27Cyanoamino acid metabolism_Homo sapiens_hsa004601.26244326
28Drug metabolism - other enzymes_Homo sapiens_hsa009831.21441885
29mRNA surveillance pathway_Homo sapiens_hsa030151.18715715
30Cysteine and methionine metabolism_Homo sapiens_hsa002701.17348989
31p53 signaling pathway_Homo sapiens_hsa041151.16846696
32Selenocompound metabolism_Homo sapiens_hsa004501.14169344
33Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.10205837
34Protein export_Homo sapiens_hsa030601.08410296
35Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.05280329
36Vitamin B6 metabolism_Homo sapiens_hsa007501.03464560
37Biosynthesis of amino acids_Homo sapiens_hsa012301.03001962
38Primary immunodeficiency_Homo sapiens_hsa053400.98572369
39Systemic lupus erythematosus_Homo sapiens_hsa053220.98228906
40Antigen processing and presentation_Homo sapiens_hsa046120.94643731
41Epstein-Barr virus infection_Homo sapiens_hsa051690.94566426
42Herpes simplex infection_Homo sapiens_hsa051680.93269734
43Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.91722499
44Glutathione metabolism_Homo sapiens_hsa004800.91026367
45Propanoate metabolism_Homo sapiens_hsa006400.90898133
46Asthma_Homo sapiens_hsa053100.88029523
47Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.84463875
48Sulfur metabolism_Homo sapiens_hsa009200.80681023
49Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.80249825
50Huntingtons disease_Homo sapiens_hsa050160.77118218
51Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.76988623
52Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.74740170
53Fructose and mannose metabolism_Homo sapiens_hsa000510.74597744
54Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.74141681
55Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.73934310
56Cardiac muscle contraction_Homo sapiens_hsa042600.73841856
57Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.73767802
58Parkinsons disease_Homo sapiens_hsa050120.67608304
59Carbon metabolism_Homo sapiens_hsa012000.64155958
60Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.63848427
61Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.62451109
62Legionellosis_Homo sapiens_hsa051340.62225335
63N-Glycan biosynthesis_Homo sapiens_hsa005100.61685730
64Viral carcinogenesis_Homo sapiens_hsa052030.60829848
65Oxidative phosphorylation_Homo sapiens_hsa001900.53731647
66Autoimmune thyroid disease_Homo sapiens_hsa053200.53661489
67Galactose metabolism_Homo sapiens_hsa000520.52161805
68Measles_Homo sapiens_hsa051620.48925633
69Metabolic pathways_Homo sapiens_hsa011000.48151419
70Other glycan degradation_Homo sapiens_hsa005110.46580618
71NF-kappa B signaling pathway_Homo sapiens_hsa040640.45786683
72Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.45730227
732-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.44545015
74Graft-versus-host disease_Homo sapiens_hsa053320.44270371
75Intestinal immune network for IgA production_Homo sapiens_hsa046720.44090712
76Tryptophan metabolism_Homo sapiens_hsa003800.42238444
77Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.41303336
78Butanoate metabolism_Homo sapiens_hsa006500.41086123
79HTLV-I infection_Homo sapiens_hsa051660.40941166
80Type I diabetes mellitus_Homo sapiens_hsa049400.39769389
81Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.38005227
82Arachidonic acid metabolism_Homo sapiens_hsa005900.36931717
83Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.36891738
84Pentose and glucuronate interconversions_Homo sapiens_hsa000400.36596399
85Transcriptional misregulation in cancer_Homo sapiens_hsa052020.34936639
86Apoptosis_Homo sapiens_hsa042100.34879506
87Hematopoietic cell lineage_Homo sapiens_hsa046400.34782912
88RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.34395817
89Arginine and proline metabolism_Homo sapiens_hsa003300.34275480
90Thyroid cancer_Homo sapiens_hsa052160.33770960
91Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.33681119
92Fatty acid metabolism_Homo sapiens_hsa012120.33210121
93Pyruvate metabolism_Homo sapiens_hsa006200.33191214
94Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.32968372
95Tyrosine metabolism_Homo sapiens_hsa003500.32311756
96SNARE interactions in vesicular transport_Homo sapiens_hsa041300.30984300
97Viral myocarditis_Homo sapiens_hsa054160.30354297
98Linoleic acid metabolism_Homo sapiens_hsa005910.29367824
99Phototransduction_Homo sapiens_hsa047440.27987811
100Fatty acid degradation_Homo sapiens_hsa000710.26870483
101Oocyte meiosis_Homo sapiens_hsa041140.26156256
102Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.25759013
103Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.25510383
104Influenza A_Homo sapiens_hsa051640.24876129
105Phenylalanine metabolism_Homo sapiens_hsa003600.24569246
106Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.24435498
107Regulation of autophagy_Homo sapiens_hsa041400.23661120
108Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.23465138
109Steroid biosynthesis_Homo sapiens_hsa001000.23270126
110Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.22635727
111Alcoholism_Homo sapiens_hsa050340.22271422
112Acute myeloid leukemia_Homo sapiens_hsa052210.21625609
113Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.21028166
114alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.20982355
115Chemical carcinogenesis_Homo sapiens_hsa052040.20139370
116Renin-angiotensin system_Homo sapiens_hsa046140.19223310
117Glycosaminoglycan degradation_Homo sapiens_hsa005310.18910125
118Shigellosis_Homo sapiens_hsa051310.18829637
119Vitamin digestion and absorption_Homo sapiens_hsa049770.17467266
120Collecting duct acid secretion_Homo sapiens_hsa049660.16645638
121beta-Alanine metabolism_Homo sapiens_hsa004100.15830896
122Peroxisome_Homo sapiens_hsa041460.15551409
123Leishmaniasis_Homo sapiens_hsa051400.15435549
124Rheumatoid arthritis_Homo sapiens_hsa053230.15181052
125Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.14842148
126Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.14428923
127Small cell lung cancer_Homo sapiens_hsa052220.13709745
128Hepatitis B_Homo sapiens_hsa051610.13576390
129Allograft rejection_Homo sapiens_hsa053300.13146053
130Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.12930773

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