ETV4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of gene silencing by miRNA (GO:0060964)6.05542646
2regulation of gene silencing by RNA (GO:0060966)6.05542646
3regulation of posttranscriptional gene silencing (GO:0060147)6.05542646
4paraxial mesoderm development (GO:0048339)5.15671315
5DNA unwinding involved in DNA replication (GO:0006268)5.00926819
6folic acid-containing compound biosynthetic process (GO:0009396)4.64357044
7nuclear pore organization (GO:0006999)4.47210429
8heterochromatin organization (GO:0070828)4.27598033
9DNA replication-dependent nucleosome organization (GO:0034723)4.24644940
10DNA replication-dependent nucleosome assembly (GO:0006335)4.24644940
11peptidyl-glutamic acid carboxylation (GO:0017187)4.22755152
12protein carboxylation (GO:0018214)4.22755152
13protein localization to kinetochore (GO:0034501)4.15826741
14very-low-density lipoprotein particle assembly (GO:0034379)4.13984742
15IMP biosynthetic process (GO:0006188)4.11901762
16nuclear pore complex assembly (GO:0051292)4.11037908
17proline biosynthetic process (GO:0006561)4.05099029
18establishment of apical/basal cell polarity (GO:0035089)4.04832823
19peptidyl-arginine omega-N-methylation (GO:0035247)4.04065896
20mitotic nuclear envelope disassembly (GO:0007077)3.98343236
21regulation of translational fidelity (GO:0006450)3.98327950
22plasma lipoprotein particle assembly (GO:0034377)3.97410626
23DNA replication initiation (GO:0006270)3.90848175
24L-serine metabolic process (GO:0006563)3.85975887
25histone arginine methylation (GO:0034969)3.79122292
26membrane disassembly (GO:0030397)3.77060928
27nuclear envelope disassembly (GO:0051081)3.77060928
28negative regulation of fibrinolysis (GO:0051918)3.74746076
29proline metabolic process (GO:0006560)3.71148044
30regulation of hippo signaling (GO:0035330)3.71009745
31polarized epithelial cell differentiation (GO:0030859)3.70816752
32nucleobase biosynthetic process (GO:0046112)3.69272883
33mitotic metaphase plate congression (GO:0007080)3.66107160
34formation of translation preinitiation complex (GO:0001731)3.65267661
35positive regulation of SMAD protein import into nucleus (GO:0060391)3.65227917
36regulation of helicase activity (GO:0051095)3.61502610
37regulation of translational termination (GO:0006449)3.56408621
38intestinal cholesterol absorption (GO:0030299)3.55710256
39pre-miRNA processing (GO:0031054)3.55085614
40IMP metabolic process (GO:0046040)3.53799516
41peptidyl-arginine N-methylation (GO:0035246)3.49793988
42peptidyl-arginine methylation (GO:0018216)3.49793988
43maturation of SSU-rRNA (GO:0030490)3.49049194
44establishment of monopolar cell polarity (GO:0061162)3.45976917
45establishment or maintenance of monopolar cell polarity (GO:0061339)3.45976917
46regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.45271042
47anterior/posterior axis specification, embryo (GO:0008595)3.45133210
48protein-lipid complex assembly (GO:0065005)3.40902279
49regulation of mitotic spindle organization (GO:0060236)3.40332328
50DNA duplex unwinding (GO:0032508)3.39806463
51DNA geometric change (GO:0032392)3.38833807
52ribosome assembly (GO:0042255)3.38670575
53DNA strand elongation involved in DNA replication (GO:0006271)3.38364175
54regulation of spindle organization (GO:0090224)3.36772986
55regulation of plasminogen activation (GO:0010755)3.35430162
56protein localization to chromosome, centromeric region (GO:0071459)3.33673958
57mitotic sister chromatid segregation (GO:0000070)3.33217256
58regulation of gene silencing (GO:0060968)3.24481556
59regulation of SMAD protein import into nucleus (GO:0060390)3.22998468
60sister chromatid segregation (GO:0000819)3.19907819
61regulation of fibrinolysis (GO:0051917)3.18070843
62DNA strand elongation (GO:0022616)3.16308328
63regulation of histone H3-K9 methylation (GO:0051570)3.13466224
64chaperone-mediated protein complex assembly (GO:0051131)3.12886220
65spliceosomal tri-snRNP complex assembly (GO:0000244)3.11750007
66establishment of viral latency (GO:0019043)3.11736390
67positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.10722816
68positive regulation of mitotic sister chromatid separation (GO:1901970)3.10722816
69positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.10722816
70purine nucleobase biosynthetic process (GO:0009113)3.09757086
71metaphase plate congression (GO:0051310)3.08967045
72somatic diversification of immune receptors via somatic mutation (GO:0002566)3.07303880
73somatic hypermutation of immunoglobulin genes (GO:0016446)3.07303880
74mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)3.06304726
75regulation of apoptotic cell clearance (GO:2000425)3.04081770
76negative regulation of histone methylation (GO:0031061)3.01567872
77serine family amino acid biosynthetic process (GO:0009070)3.01458981
78establishment of integrated proviral latency (GO:0075713)3.00179935
79pore complex assembly (GO:0046931)2.97788463
80lung epithelium development (GO:0060428)2.97536952
81regulation of sister chromatid cohesion (GO:0007063)2.96722553
82negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.94032720
83protein maturation by protein folding (GO:0022417)2.93968815
84regulation of bile acid biosynthetic process (GO:0070857)2.93367895
85negative regulation of gene silencing (GO:0060969)2.93317448
86ribosome biogenesis (GO:0042254)2.92421367
87Golgi transport vesicle coating (GO:0048200)2.91977790
88COPI coating of Golgi vesicle (GO:0048205)2.91977790
89G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.91710086
90chromatin assembly (GO:0031497)2.91253648
91low-density lipoprotein particle remodeling (GO:0034374)2.90621570
92nuclear envelope organization (GO:0006998)2.88638648
93apoptotic process involved in morphogenesis (GO:0060561)2.88033033
94positive regulation of chromosome segregation (GO:0051984)2.87047152
95regulation of cholesterol homeostasis (GO:2000188)2.86854457
96lung-associated mesenchyme development (GO:0060484)2.86683118
97ribosomal small subunit assembly (GO:0000028)2.86030726
98mitotic chromosome condensation (GO:0007076)2.83357263
99notochord development (GO:0030903)2.81794937
100double-strand break repair via nonhomologous end joining (GO:0006303)2.79329553
101non-recombinational repair (GO:0000726)2.79329553
102regulation of cholesterol esterification (GO:0010872)2.78826658
103spindle assembly involved in mitosis (GO:0090307)2.77903119
104telomere maintenance via semi-conservative replication (GO:0032201)2.75010219
105regulation of centrosome cycle (GO:0046605)2.74108601
106establishment of chromosome localization (GO:0051303)2.73059426
107telomere maintenance via recombination (GO:0000722)2.71539618
108regulation of stem cell maintenance (GO:2000036)2.71316723
109regulation of chromosome segregation (GO:0051983)2.70380965
110determination of adult lifespan (GO:0008340)2.70359034
111DNA replication checkpoint (GO:0000076)2.69483076
112protein complex localization (GO:0031503)2.69273271
113nucleotide-sugar biosynthetic process (GO:0009226)2.67360738
114nodal signaling pathway (GO:0038092)2.66932633
115cellular protein complex localization (GO:0034629)2.65116999
116mitotic recombination (GO:0006312)2.64410140
117translational initiation (GO:0006413)2.64110614
1184-hydroxyproline metabolic process (GO:0019471)2.63923419
119regulation of protein activation cascade (GO:2000257)2.62768337
120negative regulation of chromosome segregation (GO:0051985)2.62621768
121tetrahydrofolate metabolic process (GO:0046653)2.62582491
122regulation of cholesterol biosynthetic process (GO:0045540)2.61689791
123chromatin remodeling at centromere (GO:0031055)2.61547375
124microtubule cytoskeleton organization involved in mitosis (GO:1902850)2.61262083
125tRNA aminoacylation for protein translation (GO:0006418)2.61050523
126chromosome condensation (GO:0030261)2.60955022
127negative regulation of mRNA processing (GO:0050686)2.60706834
128regulation of complement activation (GO:0030449)2.59618224
129ribonucleoprotein complex biogenesis (GO:0022613)2.59247890
130plasma lipoprotein particle organization (GO:0071827)2.59049291
131mitotic G1 DNA damage checkpoint (GO:0031571)2.58968549
132protein-lipid complex remodeling (GO:0034368)2.58601963
133macromolecular complex remodeling (GO:0034367)2.58601963
134plasma lipoprotein particle remodeling (GO:0034369)2.58601963
135chromatin assembly or disassembly (GO:0006333)2.57639980
136L-alpha-amino acid transmembrane transport (GO:1902475)2.57492943
137mitotic spindle checkpoint (GO:0071174)2.57043256
138planar cell polarity pathway involved in neural tube closure (GO:0090179)2.56660468
139histone H2A monoubiquitination (GO:0035518)2.56292449
140regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.56195763
141translational termination (GO:0006415)2.55852742
142coenzyme A biosynthetic process (GO:0015937)2.55210923
143maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.54905541
144CENP-A containing nucleosome assembly (GO:0034080)2.54571451
145regulation of protein heterodimerization activity (GO:0043497)2.53651048
146viral transcription (GO:0019083)2.53608221
147mitotic spindle assembly checkpoint (GO:0007094)2.53396777
148negative regulation of mitotic sister chromatid separation (GO:2000816)2.53344611
149negative regulation of mitotic sister chromatid segregation (GO:0033048)2.53344611
150negative regulation of sister chromatid segregation (GO:0033046)2.53344611
151COPII vesicle coating (GO:0048208)2.52302591
152DNA strand renaturation (GO:0000733)2.50460083
153DNA replication-independent nucleosome organization (GO:0034724)2.50264721
154DNA replication-independent nucleosome assembly (GO:0006336)2.50264721
155cholesterol efflux (GO:0033344)2.48799642
156blood coagulation, intrinsic pathway (GO:0007597)2.44945841
157protein retention in ER lumen (GO:0006621)2.43623398
158glucose 6-phosphate metabolic process (GO:0051156)2.40124980
159pinocytosis (GO:0006907)2.39180363
160positive regulation of dendritic spine morphogenesis (GO:0061003)2.38448138
161protein-lipid complex subunit organization (GO:0071825)2.36612092
162regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.33919512
163regulation of cell fate specification (GO:0042659)2.32315845

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.93044031
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.50560186
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.11386214
4MYC_19079543_ChIP-ChIP_MESCs_Mouse3.36614110
5TP63_17297297_ChIP-ChIP_HaCaT_Human3.05295624
6E2F4_17652178_ChIP-ChIP_JURKAT_Human2.99736727
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.96416315
8ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.93612498
9POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.92142863
10KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.70893300
11KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.70893300
12KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.70893300
13* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.66727581
14SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.65579096
15EGR1_19374776_ChIP-ChIP_THP-1_Human2.65161679
16* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.59894637
17NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.55861720
18ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.48395192
19MYC_18358816_ChIP-ChIP_MESCs_Mouse2.30730555
20NELFA_20434984_ChIP-Seq_ESCs_Mouse2.22838885
21NANOG_18555785_ChIP-Seq_MESCs_Mouse2.18533286
22KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.17438603
23* TCF3_18692474_ChIP-Seq_MEFs_Mouse2.13876412
24XRN2_22483619_ChIP-Seq_HELA_Human2.13055479
25ZIC3_20872845_ChIP-ChIP_MESCs_Mouse2.07481691
26AR_21909140_ChIP-Seq_LNCAP_Human2.04245275
27MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.00190853
28STAT3_1855785_ChIP-Seq_MESCs_Mouse1.99889414
29SOX2_18555785_ChIP-Seq_MESCs_Mouse1.91362773
30MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.85790921
31ESR1_15608294_ChIP-ChIP_MCF-7_Human1.85568944
32* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.84808295
33* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.82983111
34* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.81506089
35* NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.81438039
36POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.77335151
37E2F1_21310950_ChIP-Seq_MCF-7_Human1.73291266
38MYCN_18555785_ChIP-Seq_MESCs_Mouse1.72845590
39HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.72139021
40KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.72046133
41E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.71625203
42KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.71045032
43* SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.70444194
44MYC_22102868_ChIP-Seq_BL_Human1.69003727
45* TCF3_18692474_ChIP-Seq_MESCs_Mouse1.68514635
46SALL1_21062744_ChIP-ChIP_HESCs_Human1.65467787
47CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.64955845
48HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.64818035
49CLOCK_20551151_ChIP-Seq_293T_Human1.63910934
50ETS1_20019798_ChIP-Seq_JURKAT_Human1.63545128
51* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.62219357
52PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.60687952
53NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.58907431
54ZNF263_19887448_ChIP-Seq_K562_Human1.50215619
55ZFP281_18757296_ChIP-ChIP_E14_Mouse1.50214827
56EST1_17652178_ChIP-ChIP_JURKAT_Human1.48829832
57CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.46920956
58CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.44207140
59CREB1_15753290_ChIP-ChIP_HEK293T_Human1.43952898
60RBPJ_22232070_ChIP-Seq_NCS_Mouse1.43898338
61TTF2_22483619_ChIP-Seq_HELA_Human1.43293191
62CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.42469335
63* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.40287696
64* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.39027390
65KLF4_18555785_ChIP-Seq_MESCs_Mouse1.37354135
66PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.37199792
67* SOX2_18692474_ChIP-Seq_MEFs_Mouse1.37021220
68TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.36815796
69* NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.36427450
70POU5F1_16518401_ChIP-PET_MESCs_Mouse1.35201955
71DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.34886915
72* OCT4_18692474_ChIP-Seq_MEFs_Mouse1.28644260
73SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.28541001
74NANOG_21062744_ChIP-ChIP_HESCs_Human1.28237863
75HIF1A_21447827_ChIP-Seq_MCF-7_Human1.26596819
76* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.26568186
77SOX17_20123909_ChIP-Seq_XEN_Mouse1.26521192
78THAP11_20581084_ChIP-Seq_MESCs_Mouse1.26178113
79NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.25690602
80RARG_19884340_ChIP-ChIP_MEFs_Mouse1.25350133
81* SOX2_18692474_ChIP-Seq_MESCs_Mouse1.22328462
82RXR_22158963_ChIP-Seq_LIVER_Mouse1.21134211
83DCP1A_22483619_ChIP-Seq_HELA_Human1.20756816
84* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.18252022
85JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.15302364
86SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.15136269
87CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.15135812
88* NANOG_18692474_ChIP-Seq_MEFs_Mouse1.14295165
89DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.14166632
90YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.13798875
91TP63_19390658_ChIP-ChIP_HaCaT_Human1.13676864
92TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.13241569
93NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.09812431
94CIITA_25753668_ChIP-Seq_RAJI_Human1.09595324
95CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.09183706
96GABP_19822575_ChIP-Seq_HepG2_Human1.07713361
97TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.07168776
98ATF3_27146783_Chip-Seq_COLON_Human1.06643703
99HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.05563905
100KDM5A_27292631_Chip-Seq_BREAST_Human1.05116044
101* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.03772433
102KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.03500368
103NANOG_16153702_ChIP-ChIP_HESCs_Human1.03413893
104* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.03129687
105* TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.02619305
106PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.02387946
107SOX2_16153702_ChIP-ChIP_HESCs_Human1.02211584
108CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.01859390
109* FOXA2_19822575_ChIP-Seq_HepG2_Human1.01456884
110SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.01145505
111GABP_17652178_ChIP-ChIP_JURKAT_Human0.99078164
112TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.98438744
113* EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.98233632
114PPARA_22158963_ChIP-Seq_LIVER_Mouse0.98222179
115* HNF4A_19822575_ChIP-Seq_HepG2_Human0.98062544
116PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.97928884
117* TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.97900638
118* POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.97393869
119* NANOG_18692474_ChIP-Seq_MESCs_Mouse0.97312199
120TFEB_21752829_ChIP-Seq_HELA_Human0.96469031
121CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95347645
122HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.94530586
123KAP1_27257070_Chip-Seq_ESCs_Mouse0.93920242
124FOXP3_21729870_ChIP-Seq_TREG_Human0.93294576
125VDR_23849224_ChIP-Seq_CD4+_Human0.93136680
126HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.93132899
127YY1_21170310_ChIP-Seq_MESCs_Mouse0.92696817
128PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.89228227

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000566_synostosis4.79860196
2MP0003122_maternal_imprinting3.86801218
3MP0003111_abnormal_nucleus_morphology3.19921250
4MP0004957_abnormal_blastocyst_morpholog3.12921884
5MP0010352_gastrointestinal_tract_polyps2.90048595
6MP0003693_abnormal_embryo_hatching2.89041886
7MP0003705_abnormal_hypodermis_morpholog2.86005336
8MP0010094_abnormal_chromosome_stability2.76440495
9MP0002653_abnormal_ependyma_morphology2.75346866
10MP0005360_urolithiasis2.70100180
11MP0010030_abnormal_orbit_morphology2.69878796
12MP0003077_abnormal_cell_cycle2.58620917
13MP0003123_paternal_imprinting2.43821547
14MP0000537_abnormal_urethra_morphology2.38746580
15MP0005623_abnormal_meninges_morphology2.37725757
16MP0003941_abnormal_skin_development2.36692401
17MP0001730_embryonic_growth_arrest2.23414899
18MP0005076_abnormal_cell_differentiation2.16094092
19MP0004133_heterotaxia2.13489668
20MP0009053_abnormal_anal_canal2.09123571
21MP0008007_abnormal_cellular_replicative2.07510835
22MP0000350_abnormal_cell_proliferation2.02903957
23MP0008932_abnormal_embryonic_tissue2.02763516
24MP0002084_abnormal_developmental_patter2.02491145
25MP0003283_abnormal_digestive_organ2.02446759
26MP0005257_abnormal_intraocular_pressure1.98018619
27* MP0002085_abnormal_embryonic_tissue1.95118816
28MP0004197_abnormal_fetal_growth/weight/1.93381758
29MP0003566_abnormal_cell_adhesion1.91639656
30MP0006292_abnormal_olfactory_placode1.88526864
31MP0008057_abnormal_DNA_replication1.87984842
32MP0010307_abnormal_tumor_latency1.84956290
33MP0005408_hypopigmentation1.82302170
34MP0001849_ear_inflammation1.82198172
35MP0002938_white_spotting1.77065469
36MP0010234_abnormal_vibrissa_follicle1.74812382
37MP0008058_abnormal_DNA_repair1.72692271
38MP0001672_abnormal_embryogenesis/_devel1.71136123
39MP0005380_embryogenesis_phenotype1.71136123
40MP0001697_abnormal_embryo_size1.69616340
41MP0003119_abnormal_digestive_system1.69198031
42MP0002249_abnormal_larynx_morphology1.54644530
43* MP0003942_abnormal_urinary_system1.54398167
44MP0002086_abnormal_extraembryonic_tissu1.50689488
45* MP0002080_prenatal_lethality1.50201851
46MP0003984_embryonic_growth_retardation1.49518058
47MP0002088_abnormal_embryonic_growth/wei1.46647214
48MP0001293_anophthalmia1.46273678
49* MP0000534_abnormal_ureter_morphology1.43123212
50MP0003718_maternal_effect1.42608829
51MP0002111_abnormal_tail_morphology1.42024576
52MP0001666_abnormal_nutrient_absorption1.41275916
53MP0000733_abnormal_muscle_development1.40864094
54MP0003890_abnormal_embryonic-extraembry1.40396479
55MP0002139_abnormal_hepatobiliary_system1.39287067
56MP0005365_abnormal_bile_salt1.38785354
57MP0004272_abnormal_basement_membrane1.38618334
58MP0004233_abnormal_muscle_weight1.38009268
59* MP0003937_abnormal_limbs/digits/tail_de1.36276097
60MP0003567_abnormal_fetal_cardiomyocyte1.32953586
61MP0000428_abnormal_craniofacial_morphol1.32323774
62MP0003121_genomic_imprinting1.32320336
63MP0009697_abnormal_copulation1.32218763
64MP0003806_abnormal_nucleotide_metabolis1.31151943
65MP0003115_abnormal_respiratory_system1.30118677
66MP0001661_extended_life_span1.28613392
67MP0002697_abnormal_eye_size1.27293961
68MP0000467_abnormal_esophagus_morphology1.24406477
69MP0005023_abnormal_wound_healing1.23211798
70MP0002254_reproductive_system_inflammat1.20980846
71MP0003861_abnormal_nervous_system1.19033996
72MP0000049_abnormal_middle_ear1.14834928
73MP0001286_abnormal_eye_development1.14823315
74MP0003755_abnormal_palate_morphology1.12960806
75MP0003385_abnormal_body_wall1.12291152
76MP0010329_abnormal_lipoprotein_level1.12126961
77MP0005501_abnormal_skin_physiology1.11751023
78MP0000432_abnormal_head_morphology1.08257601
79MP0001915_intracranial_hemorrhage1.07356125
80MP0002233_abnormal_nose_morphology1.05624916
81MP0002282_abnormal_trachea_morphology1.05361930
82MP0002092_abnormal_eye_morphology1.05225967
83MP0000750_abnormal_muscle_regeneration1.04658572
84MP0010368_abnormal_lymphatic_system1.04076290
85MP0000678_abnormal_parathyroid_gland1.02618336
86MP0005451_abnormal_body_composition1.01449588
87MP0009703_decreased_birth_body0.97131176
88MP0003195_calcinosis0.96914173
89MP0003935_abnormal_craniofacial_develop0.96727235
90MP0000762_abnormal_tongue_morphology0.96246058
91MP0009672_abnormal_birth_weight0.95849343
92MP0004264_abnormal_extraembryonic_tissu0.95697958
93MP0003786_premature_aging0.94194495
94MP0000516_abnormal_urinary_system0.93210021
95MP0005367_renal/urinary_system_phenotyp0.93210021
96MP0002932_abnormal_joint_morphology0.92072306
97MP0001299_abnormal_eye_distance/0.91991566
98MP0003315_abnormal_perineum_morphology0.89622845
99MP0002925_abnormal_cardiovascular_devel0.88857046
100MP0000358_abnormal_cell_content/0.85300783
101MP0004185_abnormal_adipocyte_glucose0.85232924
102MP0001348_abnormal_lacrimal_gland0.84614162
103MP0008789_abnormal_olfactory_epithelium0.84225805
104MP0002796_impaired_skin_barrier0.83653591
105MP0005275_abnormal_skin_tensile0.83215551
106MP0003136_yellow_coat_color0.83109633
107MP0008260_abnormal_autophagy0.82496238
108MP0002116_abnormal_craniofacial_bone0.81339633
109MP0000313_abnormal_cell_death0.81158194
110MP0002210_abnormal_sex_determination0.80921494
111MP0004858_abnormal_nervous_system0.80569817
112MP0002089_abnormal_postnatal_growth/wei0.79054498
113MP0002114_abnormal_axial_skeleton0.77368993
114MP0003091_abnormal_cell_migration0.76407847
115MP0005409_darkened_coat_color0.76325391
116MP0005085_abnormal_gallbladder_physiolo0.76052861
117MP0009384_cardiac_valve_regurgitation0.75804930
118MP0008438_abnormal_cutaneous_collagen0.75427155
119MP0001529_abnormal_vocalization0.74678378
120MP0005621_abnormal_cell_physiology0.74540453
121MP0003950_abnormal_plasma_membrane0.74192436
122MP0005377_hearing/vestibular/ear_phenot0.73853564
123MP0003878_abnormal_ear_physiology0.73853564
124MP0003453_abnormal_keratinocyte_physiol0.73552411
125MP0002877_abnormal_melanocyte_morpholog0.73549838
126MP0008877_abnormal_DNA_methylation0.73379566
127MP0008770_decreased_survivor_rate0.73157248
128MP0002751_abnormal_autonomic_nervous0.73030741
129MP0002234_abnormal_pharynx_morphology0.72463634
130MP0001145_abnormal_male_reproductive0.72005211
131MP0005508_abnormal_skeleton_morphology0.70954259
132MP0003943_abnormal_hepatobiliary_system0.70566528
133MP0005670_abnormal_white_adipose0.67751616
134MP0005384_cellular_phenotype0.64212214

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)6.47193744
2Ependymoma (HP:0002888)4.42375102
3Prolonged partial thromboplastin time (HP:0003645)4.37538308
4Selective tooth agenesis (HP:0001592)3.88785176
5Small epiphyses (HP:0010585)3.68599559
6Astrocytoma (HP:0009592)3.57586504
7Abnormality of the astrocytes (HP:0100707)3.57586504
8Hypoplasia of the capital femoral epiphysis (HP:0003090)3.47663927
9Esophageal atresia (HP:0002032)3.32748322
10Abnormality of the labia minora (HP:0012880)3.25044328
11Hypobetalipoproteinemia (HP:0003563)3.13989219
12Medulloblastoma (HP:0002885)3.12328552
13Joint hemorrhage (HP:0005261)3.12064031
14Absent epiphyses (HP:0010577)3.07756419
15Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)3.07756419
16Colon cancer (HP:0003003)3.06905260
17Irregular epiphyses (HP:0010582)3.03570399
18Hypercholesterolemia (HP:0003124)3.01009676
19Vaginal fistula (HP:0004320)2.94268996
20Deviation of the thumb (HP:0009603)2.87917492
21Missing ribs (HP:0000921)2.86424009
22Proximal placement of thumb (HP:0009623)2.80929058
23Abnormality of glycolysis (HP:0004366)2.80240570
24Glioma (HP:0009733)2.73623117
25Broad alveolar ridges (HP:0000187)2.72789843
26Neoplasm of the oral cavity (HP:0100649)2.71180491
27Pancreatic islet-cell hyperplasia (HP:0004510)2.70789959
28Shallow orbits (HP:0000586)2.70370810
29Supernumerary spleens (HP:0009799)2.68702663
30Hypoplastic pelvis (HP:0008839)2.67478591
31Nephroblastoma (Wilms tumor) (HP:0002667)2.66673628
32Abnormality of carpal bone ossification (HP:0006257)2.62559025
33Increased serum pyruvate (HP:0003542)2.59563342
34Pseudobulbar signs (HP:0002200)2.54631140
35Chromosomal breakage induced by crosslinking agents (HP:0003221)2.54468893
36Hepatoblastoma (HP:0002884)2.49853574
37Protrusio acetabuli (HP:0003179)2.49833902
38Short 4th metacarpal (HP:0010044)2.48451356
39Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.48451356
40Embryonal renal neoplasm (HP:0011794)2.43641198
41Agnosia (HP:0010524)2.43361427
42Biliary tract neoplasm (HP:0100574)2.43295477
43Abnormality of the common coagulation pathway (HP:0010990)2.42217374
44Absent radius (HP:0003974)2.38860438
45Flat acetabular roof (HP:0003180)2.36826353
46Hypolipoproteinemia (HP:0010981)2.34589405
47Abnormality of abdominal situs (HP:0011620)2.34056967
48Abdominal situs inversus (HP:0003363)2.34056967
49Aplasia involving forearm bones (HP:0009822)2.32888169
50Absent forearm bone (HP:0003953)2.32888169
51Xanthomatosis (HP:0000991)2.31495138
52Rhabdomyosarcoma (HP:0002859)2.31451916
53Abnormal number of incisors (HP:0011064)2.29645985
54Abnormal lung lobation (HP:0002101)2.28359480
55Broad palm (HP:0001169)2.28339924
56Trismus (HP:0000211)2.25450815
57Abnormal tarsal ossification (HP:0008369)2.24791366
58Pterygium (HP:0001059)2.24248941
59Increased nuchal translucency (HP:0010880)2.24222917
60Aplasia/hypoplasia of the humerus (HP:0006507)2.23956585
61Abnormal gallbladder physiology (HP:0012438)2.23071111
62Cholecystitis (HP:0001082)2.23071111
63Degeneration of anterior horn cells (HP:0002398)2.22894159
64Abnormality of the anterior horn cell (HP:0006802)2.22894159
65Breast hypoplasia (HP:0003187)2.22645337
66Chromsome breakage (HP:0040012)2.20832753
67Malignant gastrointestinal tract tumors (HP:0006749)2.20032156
68Gastrointestinal carcinoma (HP:0002672)2.20032156
69Short humerus (HP:0005792)2.17825347
70Asymmetry of the thorax (HP:0001555)2.15596232
71Patellar aplasia (HP:0006443)2.15073246
72Rectal fistula (HP:0100590)2.13145492
73Rectovaginal fistula (HP:0000143)2.13145492
74Meckel diverticulum (HP:0002245)2.11576490
75Atresia of the external auditory canal (HP:0000413)2.11482638
76Renal duplication (HP:0000075)2.10930643
77Spastic diplegia (HP:0001264)2.10078975
78Epiphyseal dysplasia (HP:0002656)2.09822453
79Neoplasm of the pancreas (HP:0002894)2.07707075
80Birth length less than 3rd percentile (HP:0003561)2.07296131
81Rib fusion (HP:0000902)2.06916979
82Abnormality of the calcaneus (HP:0008364)2.06599408
83Neoplasm of striated muscle (HP:0009728)2.06548587
84Carpal bone hypoplasia (HP:0001498)2.06139636
85Hemorrhage of the eye (HP:0011885)2.06008033
86Gastrointestinal atresia (HP:0002589)2.05813730
87Progressive muscle weakness (HP:0003323)2.02584298
88Adenoma sebaceum (HP:0009720)2.02425290
89Angiofibromas (HP:0010615)2.02425290
90Basal cell carcinoma (HP:0002671)2.01789399
91Skull defect (HP:0001362)2.01631944
92Abnormal ossification of hand bones (HP:0005921)2.01160124
93Ankle contracture (HP:0006466)2.00922490
94Aplasia/Hypoplasia of the patella (HP:0006498)1.99405216
95Intrahepatic cholestasis (HP:0001406)1.96738116
96Menorrhagia (HP:0000132)1.96610108
97Abnormality of the ileum (HP:0001549)1.96055868
98Hand muscle atrophy (HP:0009130)1.94711946
99Abnormality of aromatic amino acid family metabolism (HP:0004338)1.93702233
100Diastasis recti (HP:0001540)1.93679890
101Reticulocytopenia (HP:0001896)1.93234967
102Shawl scrotum (HP:0000049)1.91985582
103Breast aplasia (HP:0100783)1.90658498
104Abnormality of the lacrimal duct (HP:0011481)1.90498744
105Microglossia (HP:0000171)1.90248173
106Genu recurvatum (HP:0002816)1.89860843
107Choanal stenosis (HP:0000452)1.89192197
108Upper limb amyotrophy (HP:0009129)1.88413176
109Distal upper limb amyotrophy (HP:0007149)1.88413176
110Abnormality of the 4th metacarpal (HP:0010012)1.87415867
111Hemivertebrae (HP:0002937)1.87011521
112Intestinal fistula (HP:0100819)1.86761274
113Abnormality of the antihelix (HP:0009738)1.86089359
114Cortical dysplasia (HP:0002539)1.84711349
115Back pain (HP:0003418)1.84642262
116Hypoalphalipoproteinemia (HP:0003233)1.83384318
117Abnormality of the salivary glands (HP:0010286)1.83287762
118Premature rupture of membranes (HP:0001788)1.82853607
119Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.81808331
120High anterior hairline (HP:0009890)1.81802963
121Preauricular skin tag (HP:0000384)1.81717132
122Wide nose (HP:0000445)1.81003406
123Abnormal hand bone ossification (HP:0010660)1.80713105
124Myelomeningocele (HP:0002475)1.80608413
125Decreased lacrimation (HP:0000633)1.80502433
126Intestinal polyp (HP:0005266)1.80209758
127Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.79816103
128Fibroma (HP:0010614)1.79456558
129Broad thumb (HP:0011304)1.79363990
130Hyperglycinemia (HP:0002154)1.78252528
131Skin tags (HP:0010609)1.78222406
132Alacrima (HP:0000522)1.78028312
133Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.77742227
134Vertebral hypoplasia (HP:0008417)1.77742227
135Multiple enchondromatosis (HP:0005701)1.77224258
136Embryonal neoplasm (HP:0002898)1.77203175
137Acanthocytosis (HP:0001927)1.76847226
138Vertebral clefting (HP:0008428)1.76816711
139Ovarian neoplasm (HP:0100615)1.75958066
140Abnormal ventriculo-arterial connection (HP:0011563)1.75455495
141Transposition of the great arteries (HP:0001669)1.75455495
142Abnormal connection of the cardiac segments (HP:0011545)1.75455495
143Impaired pain sensation (HP:0007328)1.75380173
144Abnormality of pain sensation (HP:0010832)1.75380173
145Supernumerary bones of the axial skeleton (HP:0009144)1.74533179
146Biconcave vertebral bodies (HP:0004586)1.74531406
147Aplasia/Hypoplasia of the breasts (HP:0010311)1.74346260
148Breech presentation (HP:0001623)1.73545708
149Supernumerary ribs (HP:0005815)1.72814557
150Anophthalmia (HP:0000528)1.72803210
151Uterine neoplasm (HP:0010784)1.72474307
152Intestinal polyposis (HP:0200008)1.71482705
153Duplicated collecting system (HP:0000081)1.70397621
154Milia (HP:0001056)1.70009787
155Hepatocellular carcinoma (HP:0001402)1.69808291
156Horseshoe kidney (HP:0000085)1.69099525
157Aplasia/Hypoplasia of the sternum (HP:0006714)1.68805810
158Abnormality of the nasal septum (HP:0000419)1.68792879
159Facial cleft (HP:0002006)1.68668289
160Wrist flexion contracture (HP:0001239)1.68487491
161Fibrous tissue neoplasm (HP:0012316)1.68419374
162Bowel diverticulosis (HP:0005222)1.68184556
163Trigonocephaly (HP:0000243)1.67585828
164Abnormality of the Achilles tendon (HP:0005109)1.67413012
165Abnormality of endocrine pancreas physiology (HP:0012093)1.67121754
166Abnormality of the pancreatic islet cells (HP:0006476)1.67121754
167Vertebral fusion (HP:0002948)1.66787309
168Limited elbow extension (HP:0001377)1.66762694
169Abnormal sex determination (HP:0012244)1.66058263
170Sex reversal (HP:0012245)1.66058263
171Capillary hemangiomas (HP:0005306)1.66017114
172Spinal muscular atrophy (HP:0007269)1.65677495
173Tracheoesophageal fistula (HP:0002575)1.65409912
174Large earlobe (HP:0009748)1.64327158
175Oral leukoplakia (HP:0002745)1.64214743
176Ankyloglossia (HP:0010296)1.63562697
177Atrophic scars (HP:0001075)1.63560563
178Abnormality of cochlea (HP:0000375)1.63380892
179Duplication of thumb phalanx (HP:0009942)1.60876778
180Abnormality of the alveolar ridges (HP:0006477)1.60706511
181Myocardial infarction (HP:0001658)1.59252488
182Bifid scrotum (HP:0000048)1.59167300
183Arnold-Chiari malformation (HP:0002308)1.58875334
184Complement deficiency (HP:0004431)1.58447382
185Abnormality of methionine metabolism (HP:0010901)1.58279953
186Anal stenosis (HP:0002025)1.57921724
187Abnormality of the intrinsic pathway (HP:0010989)1.56536434

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA24.27633113
2FGFR43.13195377
3NEK13.12214475
4CDC73.06521215
5EEF2K3.05791930
6BUB13.05497514
7WEE12.69514652
8PKN22.65113163
9CDK122.54442399
10RPS6KB22.27373154
11LATS22.19237141
12TTK2.14751781
13VRK22.12236553
14NEK22.11407237
15PASK2.06088598
16TAOK21.96711278
17SMG11.94060496
18TSSK61.88348731
19WNK41.83611047
20PBK1.80046749
21TESK21.72706645
22TRIB31.69811571
23PAK41.68079763
24CDK71.58894014
25LMTK21.55067382
26MET1.55023706
27MAPKAPK31.53812933
28MST1R1.51572805
29ALK1.50700364
30PLK11.49748206
31MAP3K81.48550016
32PNCK1.46892938
33MAP3K101.43943784
34LATS11.43300870
35SCYL21.43058600
36MAP3K31.39024751
37TTN1.37950404
38EIF2AK11.37168351
39BMX1.32788401
40PLK31.23462382
41MKNK11.23424246
42TESK11.21457656
43FLT31.20336418
44AURKA1.20214315
45AURKB1.17608073
46TGFBR11.15792317
47CDK41.13388848
48TAOK11.13075968
49BRD41.12548589
50CHEK11.11420357
51SRPK11.11196901
52MAP3K111.09946807
53PDGFRA1.09722396
54KSR11.09521350
55ATR1.09461166
56FGFR31.07309195
57MTOR1.05933212
58FGFR11.04926181
59CHEK21.04731470
60ERBB41.03690041
61IRAK31.02448350
62TAF11.01352900
63TLK10.97762142
64PLK40.96710654
65EIF2AK30.93240957
66STK38L0.93141955
67PAK20.93089192
68ICK0.93089138
69PRKD30.92320577
70LRRK20.91027271
71STK100.90066108
72PTK20.89967064
73RPS6KA40.89332513
74DDR20.88373624
75LIMK10.87400884
76PRKCI0.85934488
77CDK20.84157075
78MKNK20.83199042
79CDK60.81473682
80DYRK30.77258085
81PAK10.74178905
82FER0.73800295
83NME10.73236179
84CDK80.72542642
85EPHB20.72515077
86PTK60.71121546
87FGFR20.69505392
88ACVR1B0.68501402
89CSNK1E0.66202626
90ATM0.65246448
91AKT20.64023843
92WNK10.63795942
93RIPK10.63580940
94BRSK20.62616409
95NTRK10.62027548
96STK160.61010622
97CDK10.60030487
98MAP2K30.59922798
99KSR20.58418812
100STK30.54906461
101CSNK1D0.54028291
102ZAK0.52462635
103PAK60.52173867
104BRAF0.52087293
105ILK0.49942751
106BRSK10.49480610
107CDK11A0.49433914
108CDK150.49232608
109CDK140.48979675
110CDK180.48492689
111CSNK2A20.47994089
112STK40.47368987
113CDK90.46010383
114NME20.45177917
115TYRO30.44148526
116ABL20.43348001
117PRKDC0.43002901
118MAP3K90.42703319
119FGR0.42620220
120DYRK20.41849555
121EIF2AK20.41156060
122PIM10.39173360
123DYRK1B0.39167624
124CSNK2A10.38865619
125VRK10.35525383
126SIK10.35464471
127DAPK10.35134119
128DYRK1A0.34746281
129MELK0.34153784
130ERBB20.33872087
131BCR0.32218628
132PDK40.31620168
133PDK30.31620168
134ARAF0.28344284
135STK390.27886184

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.81585283
2Mismatch repair_Homo sapiens_hsa034303.81566030
3One carbon pool by folate_Homo sapiens_hsa006703.44098523
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.27219797
5RNA transport_Homo sapiens_hsa030133.22002353
6Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009703.19556804
7Spliceosome_Homo sapiens_hsa030403.14626227
8Steroid biosynthesis_Homo sapiens_hsa001002.56635801
9Cell cycle_Homo sapiens_hsa041102.55955750
10Nucleotide excision repair_Homo sapiens_hsa034202.35887801
11Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.21415792
12Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.20264580
13mRNA surveillance pathway_Homo sapiens_hsa030152.05827465
14Basal cell carcinoma_Homo sapiens_hsa052172.03794027
15Base excision repair_Homo sapiens_hsa034102.01788409
16Complement and coagulation cascades_Homo sapiens_hsa046102.00947614
17Ribosome_Homo sapiens_hsa030101.97396126
18RNA polymerase_Homo sapiens_hsa030201.94752019
19Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.91633816
20Hippo signaling pathway_Homo sapiens_hsa043901.88141434
21p53 signaling pathway_Homo sapiens_hsa041151.87257891
22Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.85666615
23Homologous recombination_Homo sapiens_hsa034401.82412224
24Vitamin B6 metabolism_Homo sapiens_hsa007501.78122182
25Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.68263687
26Bladder cancer_Homo sapiens_hsa052191.66168960
27MicroRNAs in cancer_Homo sapiens_hsa052061.54025012
28Biosynthesis of amino acids_Homo sapiens_hsa012301.48192795
29Arginine biosynthesis_Homo sapiens_hsa002201.48166635
30Pyruvate metabolism_Homo sapiens_hsa006201.45236487
31Fatty acid metabolism_Homo sapiens_hsa012121.44309784
32Proteasome_Homo sapiens_hsa030501.39783869
33Fat digestion and absorption_Homo sapiens_hsa049751.38447934
34Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.38436636
35RNA degradation_Homo sapiens_hsa030181.37974415
36Pyrimidine metabolism_Homo sapiens_hsa002401.37437269
37Vitamin digestion and absorption_Homo sapiens_hsa049771.37298901
38Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.37098884
39Fatty acid elongation_Homo sapiens_hsa000621.36179802
40Hedgehog signaling pathway_Homo sapiens_hsa043401.36129563
41N-Glycan biosynthesis_Homo sapiens_hsa005101.34382120
42Galactose metabolism_Homo sapiens_hsa000521.34207208
43Adherens junction_Homo sapiens_hsa045201.30296349
44Fanconi anemia pathway_Homo sapiens_hsa034601.28287233
45Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.28165918
46Oocyte meiosis_Homo sapiens_hsa041141.27136133
47Viral carcinogenesis_Homo sapiens_hsa052031.26577542
48Small cell lung cancer_Homo sapiens_hsa052221.25252452
49Central carbon metabolism in cancer_Homo sapiens_hsa052301.23728843
50TGF-beta signaling pathway_Homo sapiens_hsa043501.22095811
51Cyanoamino acid metabolism_Homo sapiens_hsa004601.22020308
52Fatty acid biosynthesis_Homo sapiens_hsa000611.21055819
53Arginine and proline metabolism_Homo sapiens_hsa003301.19195794
54Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.17873592
55Non-homologous end-joining_Homo sapiens_hsa034501.15840455
56Thyroid cancer_Homo sapiens_hsa052161.15554783
57Systemic lupus erythematosus_Homo sapiens_hsa053221.14666858
58Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.14195172
59Proteoglycans in cancer_Homo sapiens_hsa052051.08771761
60Basal transcription factors_Homo sapiens_hsa030221.07015165
61Tight junction_Homo sapiens_hsa045301.06268889
62Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.03823120
63Notch signaling pathway_Homo sapiens_hsa043301.02238322
64HTLV-I infection_Homo sapiens_hsa051661.01319807
65Colorectal cancer_Homo sapiens_hsa052100.99787442
662-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.99232384
67Chronic myeloid leukemia_Homo sapiens_hsa052200.96222472
68Epstein-Barr virus infection_Homo sapiens_hsa051690.95443655
69Propanoate metabolism_Homo sapiens_hsa006400.94229975
70ECM-receptor interaction_Homo sapiens_hsa045120.93217372
71Melanoma_Homo sapiens_hsa052180.91266087
72Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.91214337
73Fatty acid degradation_Homo sapiens_hsa000710.90635241
74Phenylalanine metabolism_Homo sapiens_hsa003600.90495880
75Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.89086873
76Pentose and glucuronate interconversions_Homo sapiens_hsa000400.88587780
77Starch and sucrose metabolism_Homo sapiens_hsa005000.88586411
78Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.86115680
79Selenocompound metabolism_Homo sapiens_hsa004500.85750938
80Focal adhesion_Homo sapiens_hsa045100.85019544
81Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.84665066
82Wnt signaling pathway_Homo sapiens_hsa043100.83027824
83Glutathione metabolism_Homo sapiens_hsa004800.81107590
84Nitrogen metabolism_Homo sapiens_hsa009100.78779237
85Endometrial cancer_Homo sapiens_hsa052130.78451992
86Pathways in cancer_Homo sapiens_hsa052000.78308763
87Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.75520296
88Alcoholism_Homo sapiens_hsa050340.75042581
89Carbon metabolism_Homo sapiens_hsa012000.74120730
90Tyrosine metabolism_Homo sapiens_hsa003500.70015106
91Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.66917414
92HIF-1 signaling pathway_Homo sapiens_hsa040660.65231621
93Folate biosynthesis_Homo sapiens_hsa007900.65013932
94mTOR signaling pathway_Homo sapiens_hsa041500.64678228
95Glioma_Homo sapiens_hsa052140.64101018
96Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.63610714
97Maturity onset diabetes of the young_Homo sapiens_hsa049500.63233694
98Cysteine and methionine metabolism_Homo sapiens_hsa002700.61015992
99Thyroid hormone signaling pathway_Homo sapiens_hsa049190.60227286
100Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.60111100
101Purine metabolism_Homo sapiens_hsa002300.57970589
102Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.57366560
103Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.56545301
104Prostate cancer_Homo sapiens_hsa052150.56012479
105Non-small cell lung cancer_Homo sapiens_hsa052230.53939965
106Regulation of actin cytoskeleton_Homo sapiens_hsa048100.53602721
107Metabolic pathways_Homo sapiens_hsa011000.53581057
108Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.53140283
109Viral myocarditis_Homo sapiens_hsa054160.52895617
110PI3K-Akt signaling pathway_Homo sapiens_hsa041510.51453528
111PPAR signaling pathway_Homo sapiens_hsa033200.50260144
112Melanogenesis_Homo sapiens_hsa049160.49481547
113Thyroid hormone synthesis_Homo sapiens_hsa049180.48940962
114Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.48832479
115Protein export_Homo sapiens_hsa030600.47770327
116Neurotrophin signaling pathway_Homo sapiens_hsa047220.45032051
117Drug metabolism - other enzymes_Homo sapiens_hsa009830.44624312
118Apoptosis_Homo sapiens_hsa042100.43733637
119Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.43547156
120Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.42996173
121Renal cell carcinoma_Homo sapiens_hsa052110.42752831
122Pentose phosphate pathway_Homo sapiens_hsa000300.42689900
123* Transcriptional misregulation in cancer_Homo sapiens_hsa052020.41843832
124Estrogen signaling pathway_Homo sapiens_hsa049150.41379347
125Rap1 signaling pathway_Homo sapiens_hsa040150.41230360
126Renin-angiotensin system_Homo sapiens_hsa046140.39350596
127Shigellosis_Homo sapiens_hsa051310.38621874
128Lysine degradation_Homo sapiens_hsa003100.38192713
129AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.38008093
130Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.37206263
131Leukocyte transendothelial migration_Homo sapiens_hsa046700.34656749
132Fructose and mannose metabolism_Homo sapiens_hsa000510.34343528
133Pancreatic cancer_Homo sapiens_hsa052120.34083617
134Glycosaminoglycan degradation_Homo sapiens_hsa005310.33904338
135Histidine metabolism_Homo sapiens_hsa003400.33457248
136Gap junction_Homo sapiens_hsa045400.33341904
137AMPK signaling pathway_Homo sapiens_hsa041520.32674601
138Amoebiasis_Homo sapiens_hsa051460.31653130
139ErbB signaling pathway_Homo sapiens_hsa040120.30724687
140Axon guidance_Homo sapiens_hsa043600.30135958
141VEGF signaling pathway_Homo sapiens_hsa043700.29888285
142Herpes simplex infection_Homo sapiens_hsa051680.27524637
143Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.26872200
144Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.24636406
145Sulfur relay system_Homo sapiens_hsa041220.24089223
146Prion diseases_Homo sapiens_hsa050200.21774138

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »