ERICH3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1left/right axis specification (GO:0070986)6.83706816
2sperm motility (GO:0030317)6.42695408
3cilium or flagellum-dependent cell motility (GO:0001539)6.30188143
4axonemal dynein complex assembly (GO:0070286)6.26266837
5microtubule bundle formation (GO:0001578)6.23231361
6acrosome reaction (GO:0007340)6.11202231
7primary alcohol catabolic process (GO:0034310)6.07886700
8cilium movement (GO:0003341)5.99917095
9epithelial cilium movement (GO:0003351)5.77635552
10vitamin transmembrane transport (GO:0035461)5.67002470
11cilium organization (GO:0044782)5.54795398
12fusion of sperm to egg plasma membrane (GO:0007342)5.53969198
13cilium assembly (GO:0042384)5.33321733
14regulation of cilium movement (GO:0003352)5.29126318
15acrosome assembly (GO:0001675)5.20941363
16ethanol metabolic process (GO:0006067)5.19475236
17calcium ion-dependent exocytosis (GO:0017156)4.88723293
18cell wall macromolecule metabolic process (GO:0044036)4.83052323
19cell wall macromolecule catabolic process (GO:0016998)4.83052323
20epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.82419112
21diterpenoid biosynthetic process (GO:0016102)4.81429215
22motile cilium assembly (GO:0044458)4.72734680
23negative regulation of inclusion body assembly (GO:0090084)4.69821433
24positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.61096964
25multicellular organism reproduction (GO:0032504)4.60540042
26response to xenobiotic stimulus (GO:0009410)4.57237770
27plasma membrane fusion (GO:0045026)4.56133158
28regulation of short-term neuronal synaptic plasticity (GO:0048172)4.49350022
29regulation of interleukin-5 production (GO:0032674)4.47620042
30one-carbon compound transport (GO:0019755)4.45419888
31synaptic vesicle maturation (GO:0016188)4.40892781
32sperm-egg recognition (GO:0035036)4.37525662
33cellular component assembly involved in morphogenesis (GO:0010927)4.36187480
34lung epithelium development (GO:0060428)4.32144425
35spermatid development (GO:0007286)4.27018219
36negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)4.25058028
37tolerance induction (GO:0002507)4.21207559
38ventricular system development (GO:0021591)4.14190394
39centriole assembly (GO:0098534)4.11466495
40pyrimidine-containing compound transmembrane transport (GO:0072531)4.08550877
41regulation of interleukin-13 production (GO:0032656)4.07668615
42regulation of microtubule-based movement (GO:0060632)4.06461340
43reproduction (GO:0000003)4.00196492
44regulation of synaptic vesicle exocytosis (GO:2000300)3.98085450
45cell projection assembly (GO:0030031)3.93003718
46cell-cell recognition (GO:0009988)3.92006714
47negative regulation of immunoglobulin mediated immune response (GO:0002890)3.91476531
48negative regulation of B cell mediated immunity (GO:0002713)3.91476531
49lateral ventricle development (GO:0021670)3.88530315
50ethanol oxidation (GO:0006069)3.83069141
51protein localization to cilium (GO:0061512)3.80058351
52binding of sperm to zona pellucida (GO:0007339)3.77308615
53axoneme assembly (GO:0035082)3.76753080
54cilium morphogenesis (GO:0060271)3.74225411
55glomerular epithelial cell development (GO:0072310)3.72199360
56locomotory exploration behavior (GO:0035641)3.69957046
57synaptic vesicle exocytosis (GO:0016079)3.67643416
58positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.66453943
59negative regulation of humoral immune response (GO:0002921)3.65388671
60membrane depolarization during action potential (GO:0086010)3.64921389
61negative regulation of T cell differentiation in thymus (GO:0033085)3.63806178
62synaptic vesicle docking involved in exocytosis (GO:0016081)3.60372246
63sensory perception of smell (GO:0007608)3.60209429
64vocalization behavior (GO:0071625)3.59693819
65regulation of synaptic vesicle transport (GO:1902803)3.59487718
66regulation of germinal center formation (GO:0002634)3.58646712
67glutamate secretion (GO:0014047)3.57570756
68establishment of apical/basal cell polarity (GO:0035089)3.55348242
69sperm capacitation (GO:0048240)3.53026924
70cytoplasmic microtubule organization (GO:0031122)3.49740467
71detection of calcium ion (GO:0005513)3.49687790
72positive regulation of smoothened signaling pathway (GO:0045880)3.46877383
73retinal rod cell development (GO:0046548)3.40787794
74single fertilization (GO:0007338)3.38656594
75microtubule polymerization or depolymerization (GO:0031109)3.38157551
76regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.34849170
77neurotransmitter secretion (GO:0007269)3.33467675
78gonadal mesoderm development (GO:0007506)3.33047047
79retinoic acid metabolic process (GO:0042573)3.30806902
80nucleoside diphosphate phosphorylation (GO:0006165)3.29752225
81regulation of inclusion body assembly (GO:0090083)3.29366219
82membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.28799421
83regulation of glutamate receptor signaling pathway (GO:1900449)3.27158271
84retinal cone cell development (GO:0046549)3.25364129
85positive regulation of synaptic transmission, GABAergic (GO:0032230)3.24782929
86activation of protein kinase A activity (GO:0034199)3.24026153
87positive regulation of tolerance induction (GO:0002645)3.19369494
88regulation of neuronal synaptic plasticity (GO:0048168)3.17000053
89negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.16819863
90neuron cell-cell adhesion (GO:0007158)3.15889073
91protein polyglutamylation (GO:0018095)3.14608577
92microtubule severing (GO:0051013)3.13980187
93microtubule depolymerization (GO:0007019)3.13786118
94positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.12324472
95terpenoid biosynthetic process (GO:0016114)3.09998936
96establishment of monopolar cell polarity (GO:0061162)3.07738337
97establishment or maintenance of monopolar cell polarity (GO:0061339)3.07738337
98regulation of long-term neuronal synaptic plasticity (GO:0048169)3.02117008
99regulation of synapse structural plasticity (GO:0051823)3.01942514
100calcium ion import (GO:0070509)3.01713683
101response to auditory stimulus (GO:0010996)3.01435854
102regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.00879450
103ionotropic glutamate receptor signaling pathway (GO:0035235)2.98914893
104regulation of protein kinase A signaling (GO:0010738)2.98893745
105proline transport (GO:0015824)2.98620607
106cerebellar granule cell differentiation (GO:0021707)2.97272391
107CDP-diacylglycerol biosynthetic process (GO:0016024)2.96962517
108protein localization to synapse (GO:0035418)2.96835194
109exogenous drug catabolic process (GO:0042738)2.95068005
110intraciliary transport (GO:0042073)2.94775841
111auditory behavior (GO:0031223)2.92313162
112O-glycan processing (GO:0016266)2.91494678
113neuromuscular process controlling posture (GO:0050884)2.91127709
114vesicle transport along microtubule (GO:0047496)2.90932617
115apical protein localization (GO:0045176)2.90186207
116neurotransmitter transport (GO:0006836)2.89018434
117fertilization (GO:0009566)2.86634574
118neuronal action potential propagation (GO:0019227)2.85797552
119spermatogenesis (GO:0007283)2.85401258
120cellular potassium ion homeostasis (GO:0030007)2.84196677
121establishment of tissue polarity (GO:0007164)2.83626838
122establishment of planar polarity (GO:0001736)2.83626838
123male gamete generation (GO:0048232)2.83580420
124determination of left/right symmetry (GO:0007368)2.83093913
125gamma-aminobutyric acid transport (GO:0015812)2.82249454
126male meiosis (GO:0007140)2.82024813
127glycine transport (GO:0015816)2.81731752
128synaptic transmission, glutamatergic (GO:0035249)2.80791180
129synaptonemal complex organization (GO:0070193)2.80632957
130cerebellar Purkinje cell differentiation (GO:0021702)2.79842481
131sodium ion homeostasis (GO:0055078)2.79711813
132microtubule-based movement (GO:0007018)2.79622586
133exploration behavior (GO:0035640)2.77693832
134prepulse inhibition (GO:0060134)2.76948489
135regulation of calcium ion-dependent exocytosis (GO:0017158)2.76468311
136neuronal ion channel clustering (GO:0045161)2.75958300
137left/right pattern formation (GO:0060972)2.75777463
138piRNA metabolic process (GO:0034587)2.75195308
139neuron-neuron synaptic transmission (GO:0007270)2.74230470
140smoothened signaling pathway (GO:0007224)2.73492045
141regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)2.72964439
142long-chain fatty acid biosynthetic process (GO:0042759)2.72648732
143determination of bilateral symmetry (GO:0009855)2.71908896
144microtubule-based process (GO:0007017)2.69309287
145regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.68770211
146phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.68391339
147regulation of neurotransmitter secretion (GO:0046928)2.67911728
148transmission of nerve impulse (GO:0019226)2.67568821
149adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.66948504
150CDP-diacylglycerol metabolic process (GO:0046341)2.66092341
151primary alcohol metabolic process (GO:0034308)2.65810802
152positive regulation of neurotransmitter transport (GO:0051590)2.65737649
153specification of symmetry (GO:0009799)2.65157186
154cell recognition (GO:0008037)2.63762933
155long-term memory (GO:0007616)2.63461548
156striatum development (GO:0021756)2.62799052
157negative regulation of cytosolic calcium ion concentration (GO:0051481)2.62769458
158retinol metabolic process (GO:0042572)2.61986082
159regulation of synaptic transmission, glutamatergic (GO:0051966)2.61882635
160organic cation transport (GO:0015695)2.61852485
161insulin secretion (GO:0030073)2.61363284
162lateral sprouting from an epithelium (GO:0060601)2.59889091
163glutathione derivative biosynthetic process (GO:1901687)2.58966877
164glutathione derivative metabolic process (GO:1901685)2.58966877
165regulation of autophagic vacuole assembly (GO:2000785)2.58948648
166regulation of apoptotic cell clearance (GO:2000425)2.51578217
167regulation of microtubule depolymerization (GO:0031114)2.47647112
168phosphatidylethanolamine biosynthetic process (GO:0006646)2.45598476
169hydrogen peroxide biosynthetic process (GO:0050665)2.43019560
170retina layer formation (GO:0010842)2.42386103
171regulation of tolerance induction (GO:0002643)2.42350344
172aldehyde catabolic process (GO:0046185)2.39449109
173multicellular organismal water homeostasis (GO:0050891)2.36934489
174regulation of collateral sprouting (GO:0048670)2.35748645
175regulation of smoothened signaling pathway (GO:0008589)2.32237087
176organelle assembly (GO:0070925)2.28971264
177drug catabolic process (GO:0042737)2.28773679
178mitochondrion degradation (GO:0000422)2.26949805
179photoreceptor cell maintenance (GO:0045494)2.26618750
180filopodium assembly (GO:0046847)2.26336326
181phosphatidylethanolamine metabolic process (GO:0046337)2.26327588

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.60792444
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.84415204
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.64346353
4GBX2_23144817_ChIP-Seq_PC3_Human2.56422959
5REST_21632747_ChIP-Seq_MESCs_Mouse2.53393077
6FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.52217761
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.32940464
8DROSHA_22980978_ChIP-Seq_HELA_Human2.13675220
9TRIM28_21343339_ChIP-Seq_HEK293_Human2.10136804
10SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.06005612
11BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.03436770
12PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.99408891
13SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.98594812
14SUZ12_27294783_Chip-Seq_ESCs_Mouse1.87016694
15GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.86080514
16RARB_27405468_Chip-Seq_BRAIN_Mouse1.83334228
17MTF2_20144788_ChIP-Seq_MESCs_Mouse1.80212209
18EZH2_27294783_Chip-Seq_ESCs_Mouse1.78097542
19SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.77685169
20TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.75597460
21REST_18959480_ChIP-ChIP_MESCs_Mouse1.75428249
22CTBP2_25329375_ChIP-Seq_LNCAP_Human1.74659292
23ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.73558527
24ESR1_20079471_ChIP-ChIP_T-47D_Human1.69875048
25AR_21572438_ChIP-Seq_LNCaP_Human1.68382097
26SMAD4_21799915_ChIP-Seq_A2780_Human1.66473811
27NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.65572721
28JARID2_20064375_ChIP-Seq_MESCs_Mouse1.64954697
29TAF15_26573619_Chip-Seq_HEK293_Human1.63417160
30VDR_22108803_ChIP-Seq_LS180_Human1.60082739
31EZH2_27304074_Chip-Seq_ESCs_Mouse1.59742814
32SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.59324975
33SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.58314252
34CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.58266697
35RNF2_27304074_Chip-Seq_ESCs_Mouse1.57851941
36JARID2_20075857_ChIP-Seq_MESCs_Mouse1.56117734
37TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.56009836
38ZNF274_21170338_ChIP-Seq_K562_Hela1.55111623
39RNF2_18974828_ChIP-Seq_MESCs_Mouse1.54262744
40EZH2_18974828_ChIP-Seq_MESCs_Mouse1.54262744
41ZFP57_27257070_Chip-Seq_ESCs_Mouse1.53683527
42FOXM1_26456572_ChIP-Seq_MCF-7_Human1.52071068
43ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.51955731
44IKZF1_21737484_ChIP-ChIP_HCT116_Human1.45977191
45SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.45731611
46ESR2_21235772_ChIP-Seq_MCF-7_Human1.44963963
47SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.37911422
48SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.37048176
49MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.36953645
50TP53_18474530_ChIP-ChIP_U2OS_Human1.36845005
51MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.35935927
52MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.35492939
53SMC4_20622854_ChIP-Seq_HELA_Human1.35471038
54CTNNB1_20460455_ChIP-Seq_HCT116_Human1.35409736
55TP63_23658742_ChIP-Seq_EP156T_Human1.35264112
56FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.33629315
57ESR1_21235772_ChIP-Seq_MCF-7_Human1.31803763
58AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.31147466
59RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.30472302
60CBX2_27304074_Chip-Seq_ESCs_Mouse1.30326441
61STAT6_21828071_ChIP-Seq_BEAS2B_Human1.29480549
62EED_16625203_ChIP-ChIP_MESCs_Mouse1.29097854
63PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.29023378
64RNF2_27304074_Chip-Seq_NSC_Mouse1.28728213
65HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.28682828
66CTBP1_25329375_ChIP-Seq_LNCAP_Human1.27368413
67STAT3_23295773_ChIP-Seq_U87_Human1.24895132
68SMAD3_21741376_ChIP-Seq_HESCs_Human1.24789864
69TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.24385620
70RUNX1_27514584_Chip-Seq_MCF-7_Human1.24236865
71TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22414563
72PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.21876443
73P300_19829295_ChIP-Seq_ESCs_Human1.21431246
74SMAD3_21741376_ChIP-Seq_EPCs_Human1.21028642
75RAD21_21589869_ChIP-Seq_MESCs_Mouse1.20789607
76STAT1_20625510_ChIP-Seq_HELA_Human1.19571704
77EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.18471987
78TCF4_23295773_ChIP-Seq_U87_Human1.18126391
79GATA1_26923725_Chip-Seq_HPCs_Mouse1.18071850
80NANOG_18555785_Chip-Seq_ESCs_Mouse1.16397994
81AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.15764268
82SMRT_27268052_Chip-Seq_Bcells_Human1.15637177
83ETV1_20927104_ChIP-Seq_GIST48_Human1.15494710
84TOP2B_26459242_ChIP-Seq_MCF-7_Human1.15035280
85TP63_22573176_ChIP-Seq_HFKS_Human1.14354504
86AR_25329375_ChIP-Seq_VCAP_Human1.13382052
87CDX2_20551321_ChIP-Seq_CACO-2_Human1.11847715
88MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.11306620
89PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.10409834
90KLF5_25053715_ChIP-Seq_YYC3_Human1.10001351
91BMI1_23680149_ChIP-Seq_NPCS_Mouse1.09656559
92ARNT_22903824_ChIP-Seq_MCF-7_Human1.09018407
93CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.08897423
94KDM2B_26808549_Chip-Seq_REH_Human1.08574528
95SOX2_27498859_Chip-Seq_STOMACH_Mouse1.08383818
96FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.07600933
97SMAD3_21741376_ChIP-Seq_ESCs_Human1.07330325
98TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.06827769
99BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.06636570
100POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.06368564
101TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06368564
102FOXA1_25552417_ChIP-Seq_VCAP_Human1.06306720
103TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.04980154
104KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.04704106
105AHR_22903824_ChIP-Seq_MCF-7_Human1.04583416
106FLI1_27457419_Chip-Seq_LIVER_Mouse1.04193418
107IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.04033964
108CBP_20019798_ChIP-Seq_JUKART_Human1.04033964
109FLI1_21867929_ChIP-Seq_TH2_Mouse1.03812426
110PHF8_20622853_ChIP-Seq_HELA_Human1.03311322
111SOX2_21211035_ChIP-Seq_LN229_Gbm1.02735574
112PIAS1_25552417_ChIP-Seq_VCAP_Human1.02573648
113NR3C1_21868756_ChIP-Seq_MCF10A_Human1.02362601
114SMAD4_21741376_ChIP-Seq_HESCs_Human1.01639472
115CTCF_27219007_Chip-Seq_Bcells_Human1.01507137
116P53_22387025_ChIP-Seq_ESCs_Mouse1.01323888
117SOX9_24532713_ChIP-Seq_HFSC_Mouse1.01263666
118EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.01259810
119EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.01048700
120SMAD4_21741376_ChIP-Seq_EPCs_Human0.99886364
121TAL1_26923725_Chip-Seq_HPCs_Mouse0.99714375
122RUNX2_22187159_ChIP-Seq_PCA_Human0.99705210
123SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.99614683
124TDRD3_21172665_ChIP-Seq_MCF-7_Human0.99368017
125POU3F2_20337985_ChIP-ChIP_501MEL_Human0.99127924
126CDX2_19796622_ChIP-Seq_MESCs_Mouse0.98879243
127PCGF2_27294783_Chip-Seq_ESCs_Mouse0.97848641
128HNFA_21074721_ChIP-Seq_CACO-2_Human0.97816546
129CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.97510638
130WDR5_24793694_ChIP-Seq_LNCAP_Human0.97352348
131NR3C1_23031785_ChIP-Seq_PC12_Mouse0.97294650
132ELK4_26923725_Chip-Seq_MESODERM_Mouse0.96856041
133TBL1_22424771_ChIP-Seq_293T_Human0.96541862
134ER_23166858_ChIP-Seq_MCF-7_Human0.96174685
135ZNF217_24962896_ChIP-Seq_MCF-7_Human0.96168909
136SOX2_20726797_ChIP-Seq_SW620_Human0.95967907
137OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.95817908
138CMYC_18555785_Chip-Seq_ESCs_Mouse0.95673620
139AR_19668381_ChIP-Seq_PC3_Human0.95400089
140SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.95089845
141WT1_25993318_ChIP-Seq_PODOCYTE_Human0.94533297
142SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.94453213
143FOXA2_19822575_ChIP-Seq_HepG2_Human0.94336042
144CBX2_22325352_ChIP-Seq_293T-Rex_Human0.93350541
145CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92819844
146RING1B_27294783_Chip-Seq_ESCs_Mouse0.92587523
147TP53_16413492_ChIP-PET_HCT116_Human0.92577609
148E2F1_18555785_Chip-Seq_ESCs_Mouse0.91975183
149RBPJ_21746931_ChIP-Seq_IB4_Human0.91636193
150P63_26484246_Chip-Seq_KERATINOCYTES_Human0.89039519
151PRDM14_20953172_ChIP-Seq_ESCs_Human0.87737123

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization5.89454390
2MP0008875_abnormal_xenobiotic_pharmacok5.82023601
3MP0002132_abnormal_respiratory_system4.35985456
4MP0004859_abnormal_synaptic_plasticity4.30009472
5MP0004133_heterotaxia3.88559389
6MP0001984_abnormal_olfaction3.85206787
7MP0002822_catalepsy3.34422071
8MP0003880_abnormal_central_pattern3.29343489
9MP0003635_abnormal_synaptic_transmissio3.16929216
10MP0004270_analgesia3.05064183
11MP0002277_abnormal_respiratory_mucosa3.01718590
12MP0009046_muscle_twitch2.80537725
13MP0002909_abnormal_adrenal_gland2.74398997
14MP0005646_abnormal_pituitary_gland2.69928216
15MP0009745_abnormal_behavioral_response2.68497786
16MP0005423_abnormal_somatic_nervous2.63239000
17MP0002063_abnormal_learning/memory/cond2.52186811
18MP0002064_seizures2.45283453
19MP0001968_abnormal_touch/_nociception2.38890982
20MP0002572_abnormal_emotion/affect_behav2.31763557
21MP0002734_abnormal_mechanical_nocicepti2.31040294
22MP0003698_abnormal_male_reproductive2.25997850
23MP0002272_abnormal_nervous_system2.25615830
24MP0005645_abnormal_hypothalamus_physiol2.21904932
25MP0001486_abnormal_startle_reflex2.13790801
26MP0000566_synostosis2.05286541
27MP0009780_abnormal_chondrocyte_physiolo1.98427231
28MP0005377_hearing/vestibular/ear_phenot1.89554233
29MP0003878_abnormal_ear_physiology1.89554233
30MP0008789_abnormal_olfactory_epithelium1.89525548
31MP0003283_abnormal_digestive_organ1.85120094
32MP0001501_abnormal_sleep_pattern1.80970612
33MP0000383_abnormal_hair_follicle1.78710178
34MP0002282_abnormal_trachea_morphology1.69468933
35MP0002733_abnormal_thermal_nociception1.69412523
36MP0002736_abnormal_nociception_after1.67529119
37MP0001970_abnormal_pain_threshold1.67114424
38MP0002168_other_aberrant_phenotype1.66897665
39MP0002735_abnormal_chemical_nociception1.65600969
40MP0002557_abnormal_social/conspecific_i1.65515362
41MP0001929_abnormal_gametogenesis1.64300982
42MP0001346_abnormal_lacrimal_gland1.60829096
43MP0006276_abnormal_autonomic_nervous1.59859560
44MP0010678_abnormal_skin_adnexa1.59716726
45MP0002067_abnormal_sensory_capabilities1.57424173
46MP0004043_abnormal_pH_regulation1.57094399
47MP0001440_abnormal_grooming_behavior1.55953177
48MP0003879_abnormal_hair_cell1.55490455
49MP0008877_abnormal_DNA_methylation1.52006761
50MP0003122_maternal_imprinting1.49150594
51MP0002184_abnormal_innervation1.48979022
52MP0004811_abnormal_neuron_physiology1.48511958
53MP0000013_abnormal_adipose_tissue1.47044600
54MP0004019_abnormal_vitamin_homeostasis1.44913223
55MP0008569_lethality_at_weaning1.41363044
56MP0003787_abnormal_imprinting1.41161754
57MP0002653_abnormal_ependyma_morphology1.37016965
58MP0004924_abnormal_behavior1.36522406
59MP0005386_behavior/neurological_phenoty1.36522406
60MP0003633_abnormal_nervous_system1.36490445
61MP0010386_abnormal_urinary_bladder1.35735172
62MP0005220_abnormal_exocrine_pancreas1.31223302
63MP0000569_abnormal_digit_pigmentation1.26186160
64MP0003252_abnormal_bile_duct1.26144466
65MP0001502_abnormal_circadian_rhythm1.26063787
66MP0001986_abnormal_taste_sensitivity1.25307002
67MP0000678_abnormal_parathyroid_gland1.24795001
68MP0000955_abnormal_spinal_cord1.24768687
69MP0004858_abnormal_nervous_system1.23440991
70MP0002693_abnormal_pancreas_physiology1.20674653
71MP0003656_abnormal_erythrocyte_physiolo1.19692591
72MP0005379_endocrine/exocrine_gland_phen1.19045193
73MP0001529_abnormal_vocalization1.15444324
74MP0002882_abnormal_neuron_morphology1.15364903
75MP0002161_abnormal_fertility/fecundity1.15238591
76MP0002638_abnormal_pupillary_reflex1.11462027
77MP0003329_amyloid_beta_deposits1.09907797
78MP0002066_abnormal_motor_capabilities/c1.09565907
79MP0003183_abnormal_peptide_metabolism1.09268377
80MP0001765_abnormal_ion_homeostasis1.07846303
81MP0005394_taste/olfaction_phenotype1.06863733
82MP0005499_abnormal_olfactory_system1.06863733
83MP0005408_hypopigmentation1.05873687
84MP0000778_abnormal_nervous_system1.05030669
85MP0005083_abnormal_biliary_tract1.03462029
86MP0005165_increased_susceptibility_to1.02985125
87MP0005636_abnormal_mineral_homeostasis1.02185593
88MP0004145_abnormal_muscle_electrophysio1.02171157
89MP0002249_abnormal_larynx_morphology1.01831494
90MP0001485_abnormal_pinna_reflex1.01470378
91MP0002229_neurodegeneration1.00526650
92MP0001944_abnormal_pancreas_morphology0.98181564
93MP0001270_distended_abdomen0.97918850
94MP0001905_abnormal_dopamine_level0.97512207
95MP0005084_abnormal_gallbladder_morpholo0.96883467
96MP0001188_hyperpigmentation0.96699026
97MP0003631_nervous_system_phenotype0.96630053
98MP0010234_abnormal_vibrissa_follicle0.96141010
99MP0003303_peritoneal_inflammation0.95659919
100MP0005389_reproductive_system_phenotype0.95642323
101MP0005253_abnormal_eye_physiology0.95287871
102MP0000631_abnormal_neuroendocrine_gland0.94811284
103MP0002160_abnormal_reproductive_system0.93904901
104MP0005535_abnormal_body_temperature0.92884128
105MP0005551_abnormal_eye_electrophysiolog0.91822341
106MP0005395_other_phenotype0.90999900
107MP0005623_abnormal_meninges_morphology0.87733525
108MP0004885_abnormal_endolymph0.87632629
109MP0003634_abnormal_glial_cell0.86952042
110MP0002152_abnormal_brain_morphology0.85807933
111MP0002876_abnormal_thyroid_physiology0.85064105
112MP0008995_early_reproductive_senescence0.84434290
113MP0005248_abnormal_Harderian_gland0.84044734
114MP0004742_abnormal_vestibular_system0.83833774
115MP0004142_abnormal_muscle_tone0.83069906
116MP0002069_abnormal_eating/drinking_beha0.82573555
117MP0002210_abnormal_sex_determination0.82278668
118MP0003690_abnormal_glial_cell0.81100114
119MP0000681_abnormal_thyroid_gland0.80129681
120MP0003045_fibrosis0.78879491
121MP0004085_abnormal_heartbeat0.77989434
122MP0008961_abnormal_basal_metabolism0.77743190
123MP0005670_abnormal_white_adipose0.75009598
124MP0003075_altered_response_to0.73292828
125MP0005187_abnormal_penis_morphology0.72980735
126MP0001664_abnormal_digestion0.72588825
127MP0003136_yellow_coat_color0.72345374
128MP0001963_abnormal_hearing_physiology0.72071552
129MP0002234_abnormal_pharynx_morphology0.71454752
130MP0000026_abnormal_inner_ear0.69439577
131MP0002078_abnormal_glucose_homeostasis0.69391094
132MP0000462_abnormal_digestive_system0.69106747
133MP0002928_abnormal_bile_duct0.68493329
134MP0008872_abnormal_physiological_respon0.68287507
135MP0001145_abnormal_male_reproductive0.65372281
136MP0006072_abnormal_retinal_apoptosis0.65101084
137MP0001299_abnormal_eye_distance/0.65073787
138MP0002752_abnormal_somatic_nervous0.64480084
139MP0003172_abnormal_lysosome_physiology0.64392675
140MP0004883_abnormal_blood_vessel0.63848185
141MP0009703_decreased_birth_body0.61660669
142MP0002136_abnormal_kidney_physiology0.61294870
143MP0005164_abnormal_response_to0.58439110
144MP0002877_abnormal_melanocyte_morpholog0.57501396
145MP0000465_gastrointestinal_hemorrhage0.57235530
146MP0005310_abnormal_salivary_gland0.55824774

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)9.08814078
2Dynein arm defect of respiratory motile cilia (HP:0012255)8.18293522
3Absent/shortened dynein arms (HP:0200106)8.18293522
4Abnormal respiratory motile cilium physiology (HP:0012261)7.58222007
5Abnormal ciliary motility (HP:0012262)6.62438542
6Abnormal respiratory epithelium morphology (HP:0012253)6.53208773
7Abnormal respiratory motile cilium morphology (HP:0005938)6.53208773
8Rhinitis (HP:0012384)6.22588610
9Chronic bronchitis (HP:0004469)5.60253243
10Focal motor seizures (HP:0011153)4.08246024
11Infertility (HP:0000789)4.05931987
12Chronic sinusitis (HP:0011109)4.01780969
13Myokymia (HP:0002411)3.85382776
14Bronchiectasis (HP:0002110)3.48663807
15Occipital encephalocele (HP:0002085)3.34721470
16Focal seizures (HP:0007359)3.28691113
17True hermaphroditism (HP:0010459)3.12664428
18Visual hallucinations (HP:0002367)3.07111741
19Nephronophthisis (HP:0000090)3.06519785
20Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.06268238
21Atelectasis (HP:0100750)3.05656137
22Nasal polyposis (HP:0100582)3.02917321
23Chronic otitis media (HP:0000389)2.98061157
24Hyperactive renin-angiotensin system (HP:0000841)2.93614650
25Abnormality of midbrain morphology (HP:0002418)2.84393287
26Molar tooth sign on MRI (HP:0002419)2.84393287
27Atonic seizures (HP:0010819)2.79788735
28Supranuclear gaze palsy (HP:0000605)2.76891936
29Progressive cerebellar ataxia (HP:0002073)2.75301725
30Retinal dysplasia (HP:0007973)2.74251870
31Chronic hepatic failure (HP:0100626)2.70935723
32Epileptic encephalopathy (HP:0200134)2.68103249
33Medial flaring of the eyebrow (HP:0010747)2.67270976
34Bronchitis (HP:0012387)2.64635707
35Febrile seizures (HP:0002373)2.64635466
36Male infertility (HP:0003251)2.54471814
37Pancreatic cysts (HP:0001737)2.48098457
38Absence seizures (HP:0002121)2.45989049
39Abnormality of the nasal mucosa (HP:0000433)2.36938748
40Papilledema (HP:0001085)2.35741714
41Action tremor (HP:0002345)2.35407724
42Gait imbalance (HP:0002141)2.29075105
43Generalized tonic-clonic seizures (HP:0002069)2.25909098
44Limb dystonia (HP:0002451)2.24585153
45Postaxial foot polydactyly (HP:0001830)2.22541147
46Depression (HP:0000716)2.22323128
47Abnormality of the renal medulla (HP:0100957)2.20850212
48Ankle clonus (HP:0011448)2.18985779
49Recurrent bronchitis (HP:0002837)2.17036139
50Hemiparesis (HP:0001269)2.16167001
51Congenital primary aphakia (HP:0007707)2.15925544
52Dialeptic seizures (HP:0011146)2.15644740
53Postural instability (HP:0002172)2.14974712
54Impaired smooth pursuit (HP:0007772)2.13609880
55Agitation (HP:0000713)2.11181809
56Truncal ataxia (HP:0002078)2.10393915
57Bell-shaped thorax (HP:0001591)2.10286183
58Gaze-evoked nystagmus (HP:0000640)2.07296520
59Neurofibrillary tangles (HP:0002185)2.02179314
60Bundle branch block (HP:0011710)2.01947800
61Abnormality of calcium-phosphate metabolism (HP:0100530)2.01731325
62Anxiety (HP:0000739)2.00493758
63Absent frontal sinuses (HP:0002688)1.97132707
64Hyperinsulinemic hypoglycemia (HP:0000825)1.96846459
65Nephrogenic diabetes insipidus (HP:0009806)1.96771875
66Impaired vibration sensation in the lower limbs (HP:0002166)1.96659078
67Recurrent sinusitis (HP:0011108)1.96081515
68Polydipsia (HP:0001959)1.95187903
69Abnormal drinking behavior (HP:0030082)1.95187903
70Recurrent otitis media (HP:0000403)1.94239427
71Pancreatic fibrosis (HP:0100732)1.91900158
72Abnormality of ocular smooth pursuit (HP:0000617)1.90435728
73Genital tract atresia (HP:0001827)1.90313487
74Tubulointerstitial nephritis (HP:0001970)1.88509376
75Renal salt wasting (HP:0000127)1.88246523
76Ventricular fibrillation (HP:0001663)1.88034326
77Congenital hepatic fibrosis (HP:0002612)1.86442485
78Urinary bladder sphincter dysfunction (HP:0002839)1.83582636
79Torticollis (HP:0000473)1.83266523
80Male pseudohermaphroditism (HP:0000037)1.82669695
81Pheochromocytoma (HP:0002666)1.82624594
82Vaginal atresia (HP:0000148)1.81643999
83Median cleft lip (HP:0000161)1.80801041
84Aplasia/Hypoplasia of the tongue (HP:0010295)1.79912070
85Abnormal eating behavior (HP:0100738)1.79654238
86Absent rod-and cone-mediated responses on ERG (HP:0007688)1.78443105
87Failure to thrive in infancy (HP:0001531)1.73452715
88Anencephaly (HP:0002323)1.71172221
89Aplasia/Hypoplasia of the lens (HP:0008063)1.70261818
90Cerebral inclusion bodies (HP:0100314)1.69803678
91Dysdiadochokinesis (HP:0002075)1.69570478
92Abnormal EKG (HP:0003115)1.68589762
93Prolonged QT interval (HP:0001657)1.67380548
94Dyschromatopsia (HP:0007641)1.67227094
95Postaxial hand polydactyly (HP:0001162)1.66982894
96Central scotoma (HP:0000603)1.66390948
97Cystic liver disease (HP:0006706)1.65917689
98Retinal atrophy (HP:0001105)1.65867885
99Alveolar cell carcinoma (HP:0006519)1.65248466
100Abnormality of saccadic eye movements (HP:0000570)1.63439107
101Genetic anticipation (HP:0003743)1.63355996
102Hyperphosphatemia (HP:0002905)1.62106697
103Hyperkalemia (HP:0002153)1.62102623
104Oculomotor apraxia (HP:0000657)1.61302702
105Hypoglycemic seizures (HP:0002173)1.60762935
106Asplenia (HP:0001746)1.60682797
107Lower limb muscle weakness (HP:0007340)1.60409674
108Dysmetria (HP:0001310)1.60344698
109Decreased circulating renin level (HP:0003351)1.59973119
110Epileptiform EEG discharges (HP:0011182)1.59945047
111Hyperaldosteronism (HP:0000859)1.59594676
112Spastic gait (HP:0002064)1.58433285
113Aplasia/Hypoplasia of the spleen (HP:0010451)1.58286844
114Amblyopia (HP:0000646)1.58283675
115Nephropathy (HP:0000112)1.58236395
116EEG with generalized epileptiform discharges (HP:0011198)1.57244919
117Bradykinesia (HP:0002067)1.55702139
118Menstrual irregularities (HP:0000858)1.55563966
119Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.55350055
120Furrowed tongue (HP:0000221)1.55275454
121Focal dystonia (HP:0004373)1.54980549
122Type II lissencephaly (HP:0007260)1.54899919
123Specific learning disability (HP:0001328)1.54897649
124Intention tremor (HP:0002080)1.54327324
125Neuroendocrine neoplasm (HP:0100634)1.54069663
126Abnormality of renin-angiotensin system (HP:0000847)1.52323589
127Neoplasm of the tracheobronchial system (HP:0100552)1.50933612
128Tubular atrophy (HP:0000092)1.49622304
129Sclerocornea (HP:0000647)1.42404613
130Hypokalemic alkalosis (HP:0001949)1.41458086
131Abnormality of chloride homeostasis (HP:0011422)1.34240651
132Obstructive sleep apnea (HP:0002870)1.31883446
133Fetal akinesia sequence (HP:0001989)1.30049636
134Decreased central vision (HP:0007663)1.30025000
135Abnormal rod and cone electroretinograms (HP:0008323)1.29890342
136Abnormality of the dental root (HP:0006486)1.27942978
137Taurodontia (HP:0000679)1.27942978
138Abnormality of permanent molar morphology (HP:0011071)1.27942978
139Tubulointerstitial abnormality (HP:0001969)1.26120275
140Abnormality of the frontal sinuses (HP:0002687)1.26050043
141Cone-rod dystrophy (HP:0000548)1.24428352
142Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.22043226
143Short thorax (HP:0010306)1.21811442
144Hand muscle atrophy (HP:0009130)1.17116276
145Abnormality of molar morphology (HP:0011070)1.16900021
146Abnormality of molar (HP:0011077)1.16900021
147Abnormality of the dental pulp (HP:0006479)1.16563416
148Poor coordination (HP:0002370)1.16218673
149Glucose intolerance (HP:0000833)1.14971205
150Preaxial hand polydactyly (HP:0001177)1.11877250
151Bifid scrotum (HP:0000048)1.11155317
152Neoplasm of the heart (HP:0100544)1.10634745
153Hyponatremia (HP:0002902)1.09296798
154Short nail (HP:0001799)1.08480028
155Stage 5 chronic kidney disease (HP:0003774)1.07733216
156Absent speech (HP:0001344)1.04580910
157Abnormality of macular pigmentation (HP:0008002)1.04422719
158Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)0.99463877
159Abnormality of the distal phalanges of the toes (HP:0010182)0.96617250
160Supernumerary spleens (HP:0009799)0.95837582
161Bronchomalacia (HP:0002780)0.93679565

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST44.90920357
2PRKD34.80388165
3EPHA23.79204519
4NTRK33.68115336
5PDK43.34386111
6PDK33.34386111
7STK242.73200459
8EPHA42.57265963
9MAPK152.55178476
10TESK12.49922594
11MAP3K42.34785449
12MAP3K92.25661186
13MAP2K72.18856998
14PNCK2.05728363
15PDK21.97850944
16DAPK21.94557956
17INSRR1.90650175
18NTRK21.89684291
19NTRK11.86931701
20NME11.86766897
21STK381.85417198
22MAPKAPK31.84092057
23ICK1.78567446
24PRKCI1.77788551
25MINK11.77145589
26MARK11.66884340
27WNK41.65986273
28MAP3K21.65270109
29CAMKK11.65001968
30STK38L1.64031672
31EEF2K1.51406050
32ARAF1.48696355
33RIPK41.48564283
34PAK61.48141268
35CASK1.44370857
36CAMKK21.44199608
37WNK11.36484544
38PTK2B1.36360540
39BCR1.30505105
40UHMK11.26407448
41TNIK1.22514915
42PINK11.21750484
43CDK51.21073092
44TTK1.18711396
45MAP2K41.18514891
46KSR21.17048133
47PRKCG1.13174858
48GRK51.10807996
49MAP3K121.09646777
50CSK1.07686766
51FRK1.05837828
52ERBB21.04876018
53MAP3K11.03752935
54AKT31.02880360
55PRKCH1.00503210
56STK390.98227434
57SMG10.95704550
58MAP3K70.94917995
59MAP3K30.92982299
60SGK4940.92833925
61SGK2230.92833925
62PDK10.91383835
63MAPK130.90138027
64SGK20.87336750
65PAK30.86835771
66CAMK1G0.86667347
67PHKG10.86516791
68PHKG20.86516791
69CAMK2A0.85374220
70PASK0.85149661
71TYRO30.84408165
72PRPF4B0.81964301
73CAMK2B0.81779723
74DAPK10.80852750
75NEK60.79477425
76IRAK20.78965877
77MST1R0.78741312
78TRPM70.76777961
79HIPK20.75146878
80SGK30.75033269
81PDPK10.74316412
82EPHB10.73400862
83MAP3K50.71894302
84LMTK20.71849365
85WNK30.70831929
86CAMK2D0.70526492
87CDC42BPA0.69315243
88TLK10.68981739
89TNK20.68292050
90STK100.66025082
91BRAF0.65747550
92TAF10.65109169
93MAPKAPK50.64546788
94BMPR20.64072273
95EPHA30.64042522
96STK110.63829803
97CAMK10.63227696
98FES0.61806324
99LRRK20.61262925
100IRAK10.60094135
101MARK20.57479483
102CAMK2G0.55047124
103PRKCQ0.54579679
104PRKCE0.52972364
105ERBB30.51494489
106RIPK10.51056753
107RET0.49496529
108ROCK20.49412209
109RPS6KA20.48933889
110DYRK1B0.47836195
111PLK20.46649683
112CDK180.45440966
113SGK10.45408704
114FER0.44451266
115CDK150.44269570
116CDK140.42621136
117TAOK30.42171222
118RPS6KA30.42119975
119DYRK1A0.40100046
120PRKCD0.39519914
121KSR10.38807924
122FYN0.38695838
123MUSK0.38681369
124SIK20.38170709
125TBK10.38032603
126CDK190.37606095
127MAPK100.36124939
128PRKD20.35864842
129PRKCZ0.35615029
130PRKACA0.34341007
131CDK11A0.34308788
132ALK0.33519974
133PRKCA0.32873181
134OXSR10.32578948
135LATS20.31807485
136ROCK10.31553528
137PRKAA20.29042419
138BLK0.28471009
139FGFR30.27226807
140AURKA0.26979291

Predicted pathways (KEGG)

RankGene SetZ-score
1Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009804.32344565
2Phenylalanine metabolism_Homo sapiens_hsa003603.90174364
3Histidine metabolism_Homo sapiens_hsa003403.85050333
4Olfactory transduction_Homo sapiens_hsa047403.68776686
5Chemical carcinogenesis_Homo sapiens_hsa052043.52499421
6Drug metabolism - cytochrome P450_Homo sapiens_hsa009823.38096284
7Synaptic vesicle cycle_Homo sapiens_hsa047212.95021363
8Insulin secretion_Homo sapiens_hsa049112.86145304
9Tyrosine metabolism_Homo sapiens_hsa003502.86082195
10Nicotine addiction_Homo sapiens_hsa050332.73273293
11Amphetamine addiction_Homo sapiens_hsa050312.62516281
12beta-Alanine metabolism_Homo sapiens_hsa004102.47783956
13Circadian entrainment_Homo sapiens_hsa047132.41738202
14GABAergic synapse_Homo sapiens_hsa047272.35142793
15Morphine addiction_Homo sapiens_hsa050322.25426070
16Long-term potentiation_Homo sapiens_hsa047202.20329382
17Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.18452508
18Huntingtons disease_Homo sapiens_hsa050162.11273778
19Cocaine addiction_Homo sapiens_hsa050302.10102899
20Taste transduction_Homo sapiens_hsa047422.09536739
21Caffeine metabolism_Homo sapiens_hsa002322.08858722
22Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.06462766
23Glutamatergic synapse_Homo sapiens_hsa047242.06307052
24Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.05216487
25Dopaminergic synapse_Homo sapiens_hsa047281.96053157
26Salivary secretion_Homo sapiens_hsa049701.86988225
27Renin secretion_Homo sapiens_hsa049241.76303135
28Gastric acid secretion_Homo sapiens_hsa049711.70219575
29Aldosterone synthesis and secretion_Homo sapiens_hsa049251.66869489
30Retinol metabolism_Homo sapiens_hsa008301.66207263
31Type II diabetes mellitus_Homo sapiens_hsa049301.64314540
32Glutathione metabolism_Homo sapiens_hsa004801.64102724
33Cholinergic synapse_Homo sapiens_hsa047251.62432727
34Maturity onset diabetes of the young_Homo sapiens_hsa049501.57620401
35ABC transporters_Homo sapiens_hsa020101.51577061
36Collecting duct acid secretion_Homo sapiens_hsa049661.48476493
37Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.46291113
38Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.45430908
39Calcium signaling pathway_Homo sapiens_hsa040201.44832612
40Carbohydrate digestion and absorption_Homo sapiens_hsa049731.44001561
41Serotonergic synapse_Homo sapiens_hsa047261.42547022
42Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.42319641
43Sphingolipid metabolism_Homo sapiens_hsa006001.41893734
44cAMP signaling pathway_Homo sapiens_hsa040241.35749634
45Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.34506177
46Type I diabetes mellitus_Homo sapiens_hsa049401.30012200
47Dorso-ventral axis formation_Homo sapiens_hsa043201.26862248
48Estrogen signaling pathway_Homo sapiens_hsa049151.25122534
49Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.24004055
50Vibrio cholerae infection_Homo sapiens_hsa051101.23795658
51Oxytocin signaling pathway_Homo sapiens_hsa049211.22661419
52Glucagon signaling pathway_Homo sapiens_hsa049221.20645982
53Phosphatidylinositol signaling system_Homo sapiens_hsa040701.16464351
54Thyroid hormone synthesis_Homo sapiens_hsa049181.15828835
55Tight junction_Homo sapiens_hsa045301.15546788
56cGMP-PKG signaling pathway_Homo sapiens_hsa040221.15494313
57Pancreatic secretion_Homo sapiens_hsa049721.13242658
58Steroid hormone biosynthesis_Homo sapiens_hsa001401.05879585
59Gap junction_Homo sapiens_hsa045401.05403809
60GnRH signaling pathway_Homo sapiens_hsa049121.02280181
61Vascular smooth muscle contraction_Homo sapiens_hsa042701.01315942
62Long-term depression_Homo sapiens_hsa047301.00946751
63Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.99780607
64Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.95071852
65Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.89914860
66Phototransduction_Homo sapiens_hsa047440.89868785
67Cardiac muscle contraction_Homo sapiens_hsa042600.88194702
68Oocyte meiosis_Homo sapiens_hsa041140.84183619
69Arachidonic acid metabolism_Homo sapiens_hsa005900.83760282
70Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.82894302
71Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.81539166
72Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.79334870
73Fatty acid biosynthesis_Homo sapiens_hsa000610.79298167
74Melanogenesis_Homo sapiens_hsa049160.77200331
75SNARE interactions in vesicular transport_Homo sapiens_hsa041300.74287994
76Starch and sucrose metabolism_Homo sapiens_hsa005000.70979996
77Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.70575710
78Fatty acid degradation_Homo sapiens_hsa000710.69711828
79Alcoholism_Homo sapiens_hsa050340.66992054
80Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.66909187
81Inositol phosphate metabolism_Homo sapiens_hsa005620.63355882
82Peroxisome_Homo sapiens_hsa041460.61890533
83Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.61354053
84Glycerophospholipid metabolism_Homo sapiens_hsa005640.60618227
85Mineral absorption_Homo sapiens_hsa049780.60185339
86Ovarian steroidogenesis_Homo sapiens_hsa049130.58350235
87Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.57291147
88Circadian rhythm_Homo sapiens_hsa047100.57052479
89Glioma_Homo sapiens_hsa052140.56984433
90Glycosaminoglycan degradation_Homo sapiens_hsa005310.56304173
91MAPK signaling pathway_Homo sapiens_hsa040100.55824578
92Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.55386215
93Bile secretion_Homo sapiens_hsa049760.55228333
94ErbB signaling pathway_Homo sapiens_hsa040120.54848519
95Prion diseases_Homo sapiens_hsa050200.54443761
96Basal cell carcinoma_Homo sapiens_hsa052170.53834567
97Phospholipase D signaling pathway_Homo sapiens_hsa040720.52902152
98Dilated cardiomyopathy_Homo sapiens_hsa054140.50479693
99Thyroid hormone signaling pathway_Homo sapiens_hsa049190.50199203
100Axon guidance_Homo sapiens_hsa043600.49248161
101Hepatitis C_Homo sapiens_hsa051600.48725579
102Longevity regulating pathway - mammal_Homo sapiens_hsa042110.47934643
103Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.47730829
104Notch signaling pathway_Homo sapiens_hsa043300.47566534
105Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.47146567
106Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.44845340
107Endocytosis_Homo sapiens_hsa041440.44499912
108Ether lipid metabolism_Homo sapiens_hsa005650.44498860
109Primary bile acid biosynthesis_Homo sapiens_hsa001200.43381236
110Insulin signaling pathway_Homo sapiens_hsa049100.40781582
111Ras signaling pathway_Homo sapiens_hsa040140.39080848
112Leukocyte transendothelial migration_Homo sapiens_hsa046700.38918096
113Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.37920520
114Neurotrophin signaling pathway_Homo sapiens_hsa047220.37697694
115Complement and coagulation cascades_Homo sapiens_hsa046100.37084877
116alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.34428945
117Vitamin B6 metabolism_Homo sapiens_hsa007500.33110733
118Drug metabolism - other enzymes_Homo sapiens_hsa009830.33063912
119Nitrogen metabolism_Homo sapiens_hsa009100.31119945
120Sphingolipid signaling pathway_Homo sapiens_hsa040710.30970373
121Adherens junction_Homo sapiens_hsa045200.30768033
122Sulfur metabolism_Homo sapiens_hsa009200.29954932
123Linoleic acid metabolism_Homo sapiens_hsa005910.29922484
124Rap1 signaling pathway_Homo sapiens_hsa040150.29553356
125Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29319728
126Adipocytokine signaling pathway_Homo sapiens_hsa049200.29170405
127Rheumatoid arthritis_Homo sapiens_hsa053230.29102938
128Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.29052194
129Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.27893775
130Wnt signaling pathway_Homo sapiens_hsa043100.27677469
131Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.27669312
132PPAR signaling pathway_Homo sapiens_hsa033200.27450090
133Prolactin signaling pathway_Homo sapiens_hsa049170.27381017
134Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.27013795
135Choline metabolism in cancer_Homo sapiens_hsa052310.26578658
136Hedgehog signaling pathway_Homo sapiens_hsa043400.24701131
137Regulation of autophagy_Homo sapiens_hsa041400.23086204

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