EQTN

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement (GO:0003351)9.94281940
2axonemal dynein complex assembly (GO:0070286)9.70194773
3response to pheromone (GO:0019236)9.58469333
4motile cilium assembly (GO:0044458)9.46151927
5spermatid development (GO:0007286)8.91507372
6cilium movement (GO:0003341)8.15379610
7single fertilization (GO:0007338)7.95271644
8epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.87650256
9male meiosis (GO:0007140)7.71707686
10regulation of cilium movement (GO:0003352)7.06683014
11synaptonemal complex assembly (GO:0007130)6.99436546
12synaptonemal complex organization (GO:0070193)6.98434411
13sperm capacitation (GO:0048240)6.95775831
14protein targeting to Golgi (GO:0000042)6.89304255
15piRNA metabolic process (GO:0034587)6.87099972
16establishment of protein localization to Golgi (GO:0072600)6.73878876
17rRNA methylation (GO:0031167)6.54337788
18retrograde transport, vesicle recycling within Golgi (GO:0000301)6.41192675
19fertilization (GO:0009566)6.38561700
20spermatid nucleus differentiation (GO:0007289)6.19817109
21microtubule depolymerization (GO:0007019)6.02771099
22spermatogenesis (GO:0007283)5.83368805
23male gamete generation (GO:0048232)5.81041343
24phosphatidylethanolamine biosynthetic process (GO:0006646)5.73937669
25rRNA modification (GO:0000154)5.42380504
26gamete generation (GO:0007276)5.35954230
27negative regulation of inclusion body assembly (GO:0090084)5.34004008
28organic cation transport (GO:0015695)5.32993551
29cell recognition (GO:0008037)5.29678127
30phosphatidylethanolamine metabolic process (GO:0046337)5.21739393
31ventricular system development (GO:0021591)5.15343642
32positive regulation of Rab GTPase activity (GO:0032851)5.11680190
33regulation of Rab GTPase activity (GO:0032313)5.11680190
34protein localization to Golgi apparatus (GO:0034067)5.10271521
35regulation of transcription involved in cell fate commitment (GO:0060850)5.06433704
36* cellular process involved in reproduction in multicellular organism (GO:0022412)4.99743175
37germ cell development (GO:0007281)4.97834343
38chromosome organization involved in meiosis (GO:0070192)4.78202746
39RNA destabilization (GO:0050779)4.74271856
40* calcium ion-dependent exocytosis (GO:0017156)4.69966787
41cellular ketone body metabolic process (GO:0046950)4.64395456
42regulation of inclusion body assembly (GO:0090083)4.50056835
43monoubiquitinated protein deubiquitination (GO:0035520)4.48192643
44DNA methylation involved in gamete generation (GO:0043046)4.45839615
45meiotic nuclear division (GO:0007126)4.41086432
46male meiosis I (GO:0007141)4.38061870
47protein K11-linked deubiquitination (GO:0035871)4.31228685
48glycerol ether metabolic process (GO:0006662)4.26578171
49regulation of microtubule-based movement (GO:0060632)4.24557725
50microtubule severing (GO:0051013)4.23429851
51multicellular organismal reproductive process (GO:0048609)4.20250579
52ketone body metabolic process (GO:1902224)4.07588422
53coenzyme catabolic process (GO:0009109)4.04594469
54chromatin silencing (GO:0006342)3.94994499
55sexual reproduction (GO:0019953)3.93654310
56ether metabolic process (GO:0018904)3.92829861
57multicellular organismal movement (GO:0050879)3.87316192
58musculoskeletal movement (GO:0050881)3.87316192
59seminiferous tubule development (GO:0072520)3.80756946
60meiosis I (GO:0007127)3.62570630
61centriole assembly (GO:0098534)3.59767702
62chaperone-mediated protein complex assembly (GO:0051131)3.57791786
63left/right pattern formation (GO:0060972)3.57703403
64microtubule nucleation (GO:0007020)3.56043581
65antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.53316823
66genitalia morphogenesis (GO:0035112)3.50149414
67multicellular organismal development (GO:0007275)3.39745288
68single strand break repair (GO:0000012)3.38698571
69membrane protein intracellular domain proteolysis (GO:0031293)3.34779128
70protein localization to cilium (GO:0061512)3.33120865
71polyamine biosynthetic process (GO:0006596)3.31983633
72negative regulation of Rho protein signal transduction (GO:0035024)3.26433900
73centriole replication (GO:0007099)3.26012813
74glomerular visceral epithelial cell development (GO:0072015)3.24198699
75intraciliary transport (GO:0042073)3.23793012
76microtubule polymerization or depolymerization (GO:0031109)3.23054295
77cerebral cortex neuron differentiation (GO:0021895)3.20415543
78chromosome condensation (GO:0030261)3.20102296
79intra-Golgi vesicle-mediated transport (GO:0006891)3.19606029
80polyol catabolic process (GO:0046174)3.16252473
81protein polyglutamylation (GO:0018095)3.15669950
82response to acidic pH (GO:0010447)3.14911456
83Golgi to endosome transport (GO:0006895)3.12655014
84amino-acid betaine transport (GO:0015838)3.09557440
85carnitine transport (GO:0015879)3.09557440
86glomerular epithelial cell development (GO:0072310)3.07010547
87cilium organization (GO:0044782)3.06134956
88cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.06091533
89detection of chemical stimulus involved in sensory perception of smell (GO:0050911)3.04131719
90C4-dicarboxylate transport (GO:0015740)3.02052386
91protein depolymerization (GO:0051261)3.01879347
92carnitine transmembrane transport (GO:1902603)2.99379020
93cilium assembly (GO:0042384)2.98873468
94vesicle transport along microtubule (GO:0047496)2.96741402
95DNA packaging (GO:0006323)2.96355763
96spinal cord motor neuron differentiation (GO:0021522)2.95655968
97cellular component assembly involved in morphogenesis (GO:0010927)2.93832775
98regulation of somitogenesis (GO:0014807)2.93650703
99alditol metabolic process (GO:0019400)2.90659185
100microtubule-based movement (GO:0007018)2.88916023
101cilium morphogenesis (GO:0060271)2.86825944
102meiotic cell cycle (GO:0051321)2.84739569
103axoneme assembly (GO:0035082)2.83417818
104alanine transport (GO:0032328)2.82902485
105positive regulation of guanylate cyclase activity (GO:0031284)2.82844029
106macroautophagy (GO:0016236)2.81398529
107regulation of interleukin-13 production (GO:0032656)2.78346118
108cellular response to pH (GO:0071467)2.77880701
109negative regulation of gene expression, epigenetic (GO:0045814)2.75761308
110lactate metabolic process (GO:0006089)2.74850433
111synapsis (GO:0007129)2.74157175
112sequestering of actin monomers (GO:0042989)2.73979735
113regulation of guanylate cyclase activity (GO:0031282)2.72121094
114glycolytic process (GO:0006096)2.71474841
115nucleoside diphosphate phosphorylation (GO:0006165)2.70771718
116nonmotile primary cilium assembly (GO:0035058)2.70258083
117nucleus organization (GO:0006997)2.69572753
118glycerol metabolic process (GO:0006071)2.69111927
119positive regulation of macrophage activation (GO:0043032)2.67491189
120cranial nerve morphogenesis (GO:0021602)2.66173251
121meiotic cell cycle process (GO:1903046)2.64654032
122GTP biosynthetic process (GO:0006183)2.61131752
123peptidyl-threonine dephosphorylation (GO:0035970)2.58759834
124regulation of centriole replication (GO:0046599)2.57157064
125regulation of spindle checkpoint (GO:0090231)2.56944343
126mitotic sister chromatid cohesion (GO:0007064)2.52827804
127calcium ion import (GO:0070509)2.49708397
128protein refolding (GO:0042026)2.48495209
129gene silencing by RNA (GO:0031047)2.47788099
130sister chromatid cohesion (GO:0007062)2.46951232
131regulation of meiosis I (GO:0060631)2.44867334
132negative regulation of organelle assembly (GO:1902116)2.43817240
133cell wall macromolecule catabolic process (GO:0016998)17.1189896
134cell wall macromolecule metabolic process (GO:0044036)17.1189896
135* fusion of sperm to egg plasma membrane (GO:0007342)14.4654875
136multicellular organism reproduction (GO:0032504)13.0744993
137acrosome assembly (GO:0001675)12.6947799
138sperm motility (GO:0030317)12.3251361
139sperm-egg recognition (GO:0035036)11.9563926
140cilium or flagellum-dependent cell motility (GO:0001539)11.8872487
141reproduction (GO:0000003)11.0438424
142* plasma membrane fusion (GO:0045026)10.7954243
143cell-cell recognition (GO:0009988)10.7496604
144acrosome reaction (GO:0007340)10.4515911
145binding of sperm to zona pellucida (GO:0007339)10.1784577

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.83462017
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.50663294
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.05203835
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.78756473
5SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.20808219
6MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human3.18975289
7PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse3.10904034
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.99488285
9EZH2_22144423_ChIP-Seq_EOC_Human2.90067454
10FLI1_27457419_Chip-Seq_LIVER_Mouse2.61580859
11CBX2_27304074_Chip-Seq_ESCs_Mouse2.43996935
12ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.43804849
13CTBP1_25329375_ChIP-Seq_LNCAP_Human2.41481857
14PCGF2_27294783_Chip-Seq_ESCs_Mouse2.33399824
15KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse2.12141368
16GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.12128304
17ZNF274_21170338_ChIP-Seq_K562_Hela2.05683588
18ZFP57_27257070_Chip-Seq_ESCs_Mouse2.01560846
19UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human2.00619961
20KAP1_22055183_ChIP-Seq_ESCs_Mouse1.97571620
21TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.92488265
22RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.88246491
23CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.85689258
24ERA_21632823_ChIP-Seq_H3396_Human1.81743689
25DROSHA_22980978_ChIP-Seq_HELA_Human1.80333330
26KDM2B_26808549_Chip-Seq_REH_Human1.79244972
27EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.79053914
28VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.75078130
29P300_19829295_ChIP-Seq_ESCs_Human1.74812110
30MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.74506750
31TAL1_26923725_Chip-Seq_HPCs_Mouse1.73638422
32SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.73038862
33VDR_22108803_ChIP-Seq_LS180_Human1.71455299
34GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.70458969
35PCGF2_27294783_Chip-Seq_NPCs_Mouse1.67426003
36STAT6_21828071_ChIP-Seq_BEAS2B_Human1.67364691
37STAT1_17558387_ChIP-Seq_HELA_Human1.66962644
38SMAD4_21741376_ChIP-Seq_EPCs_Human1.66768023
39SUZ12_27294783_Chip-Seq_NPCs_Mouse1.65963805
40TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.65938271
41NFE2_27457419_Chip-Seq_LIVER_Mouse1.65575983
42RAC3_21632823_ChIP-Seq_H3396_Human1.64736317
43NANOG_20526341_ChIP-Seq_ESCs_Human1.62430598
44GBX2_23144817_ChIP-Seq_PC3_Human1.60331724
45EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.60078083
46SMAD3_21741376_ChIP-Seq_EPCs_Human1.59968394
47MYC_19829295_ChIP-Seq_ESCs_Human1.59720657
48CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.59478463
49ELK4_26923725_Chip-Seq_MESODERM_Mouse1.59401168
50ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.57408331
51AR_25329375_ChIP-Seq_VCAP_Human1.56815427
52ELF1_20517297_ChIP-Seq_JURKAT_Human1.56354431
53RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.56132876
54CTBP2_25329375_ChIP-Seq_LNCAP_Human1.53790311
55TAF2_19829295_ChIP-Seq_ESCs_Human1.53720300
56FLI1_21867929_ChIP-Seq_TH2_Mouse1.51066862
57AUTS2_25519132_ChIP-Seq_293T-REX_Human1.49875397
58EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.48766057
59WDR5_24793694_ChIP-Seq_LNCAP_Human1.48610304
60CRX_20693478_ChIP-Seq_RETINA_Mouse1.48290322
61NANOG_18555785_Chip-Seq_ESCs_Mouse1.46996417
62GATA1_26923725_Chip-Seq_HPCs_Mouse1.45936579
63CMYC_18555785_Chip-Seq_ESCs_Mouse1.43507534
64SMAD3_21741376_ChIP-Seq_ESCs_Human1.43134491
65NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.42968777
66TOP2B_26459242_ChIP-Seq_MCF-7_Human1.41766204
67ARNT_22903824_ChIP-Seq_MCF-7_Human1.41167533
68OCT4_18555785_Chip-Seq_ESCs_Mouse1.40181593
69RNF2_27304074_Chip-Seq_NSC_Mouse1.39616112
70GATA3_21867929_ChIP-Seq_CD8_Mouse1.38996037
71KLF5_20875108_ChIP-Seq_MESCs_Mouse1.37563802
72P53_22387025_ChIP-Seq_ESCs_Mouse1.37171956
73MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.36659702
74SOX2_22085726_ChIP-Seq_NPCs_Mouse1.36600483
75CBP_20019798_ChIP-Seq_JUKART_Human1.36481236
76IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.36481236
77EZH2_27294783_Chip-Seq_NPCs_Mouse1.34994660
78ERG_20517297_ChIP-Seq_VCAP_Human1.34083663
79CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.33857159
80ETV2_25802403_ChIP-Seq_MESCs_Mouse1.33804769
81SMAD4_21799915_ChIP-Seq_A2780_Human1.33658729
82FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.33380349
83GATA3_21867929_ChIP-Seq_TH1_Mouse1.32976434
84OCT4_20526341_ChIP-Seq_ESCs_Human1.31927867
85REST_21632747_ChIP-Seq_MESCs_Mouse1.31809318
86EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.30848547
87AR_21572438_ChIP-Seq_LNCaP_Human1.30783521
88P300_18555785_Chip-Seq_ESCs_Mouse1.30676722
89SUZ12_18555785_Chip-Seq_ESCs_Mouse1.30365484
90LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.29678764
91STAT3_23295773_ChIP-Seq_U87_Human1.28910679
92KLF4_18555785_Chip-Seq_ESCs_Mouse1.28511597
93TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27338917
94GATA3_21878914_ChIP-Seq_MCF-7_Human1.25884334
95HNFA_21074721_ChIP-Seq_CACO-2_Human1.25857108
96BCL6_27268052_Chip-Seq_Bcells_Human1.25242113
97SMAD4_21741376_ChIP-Seq_HESCs_Human1.25192854
98PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.24808179
99RUNX2_22187159_ChIP-Seq_PCA_Human1.24741853
100CBX2_22325352_ChIP-Seq_293T-Rex_Human1.23677925
101ESRRB_18555785_Chip-Seq_ESCs_Mouse1.23646045
102FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.23509348
103SUZ12_27294783_Chip-Seq_ESCs_Mouse1.23193015
104SOX2_18555785_Chip-Seq_ESCs_Mouse1.23122939
105TP53_18474530_ChIP-ChIP_U2OS_Human1.22905159
106E2F1_20622854_ChIP-Seq_HELA_Human1.22633961
107STAT3_18555785_Chip-Seq_ESCs_Mouse1.21774961
108RBPJ_21746931_ChIP-Seq_IB4_Human1.21525142
109CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.21094982
110CTCF_27219007_Chip-Seq_Bcells_Human1.20996900
111CTCF_20526341_ChIP-Seq_ESCs_Human1.19288969
112TBL1_22424771_ChIP-Seq_293T_Human1.19044548
113SMC4_20622854_ChIP-Seq_HELA_Human1.18921425
114NANOG_19829295_ChIP-Seq_ESCs_Human1.18453189
115SOX2_19829295_ChIP-Seq_ESCs_Human1.18453189
116ETV1_20927104_ChIP-Seq_GIST48_Human1.18399109
117CTCF_18555785_Chip-Seq_ESCs_Mouse1.18015861
118MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.17583174
119TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.17406257
120OCT4_21477851_ChIP-Seq_ESCs_Mouse1.17137715
121YY1_22570637_ChIP-Seq_MALME-3M_Human1.16722794
122TDRD3_21172665_ChIP-Seq_MCF-7_Human1.15005887
123RUNX1_26923725_Chip-Seq_HPCs_Mouse1.14580540
124TAF15_26573619_Chip-Seq_HEK293_Human1.14165073
125PHF8_20622854_ChIP-Seq_HELA_Human1.13711826
126GF1_26923725_Chip-Seq_HPCs_Mouse1.13631083
127PHF8_20622853_ChIP-Seq_HELA_Human1.13156215
128E2F1_18555785_Chip-Seq_ESCs_Mouse1.12219676
129PU1_27457419_Chip-Seq_LIVER_Mouse1.11912320
130EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.11043232
131KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.10785613
132TP63_19390658_ChIP-ChIP_HaCaT_Human1.10530916
133RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.10462937
134RUNX1_27457419_Chip-Seq_LIVER_Mouse1.10429884
135SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.10067149
136FOXA1_21572438_ChIP-Seq_LNCaP_Human1.09571273
137NR3C1_21868756_ChIP-Seq_MCF10A_Human1.08575935
138EZH2_27294783_Chip-Seq_ESCs_Mouse1.07582283
139NFYA_21822215_ChIP-Seq_K562_Human1.07428546
140BCOR_27268052_Chip-Seq_Bcells_Human1.07147976
141SMAD1_18555785_Chip-Seq_ESCs_Mouse1.06584472
142SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.06243209
143CEBPB_22108803_ChIP-Seq_LS180_Human1.05897532
144P53_21459846_ChIP-Seq_SAOS-2_Human1.05753755
145NMYC_18555785_Chip-Seq_ESCs_Mouse1.05686747
146AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.04252901
147TP63_22573176_ChIP-Seq_HFKS_Human1.04011080
148CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.03275924
149POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.03051745
150TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03051745
151PRDM14_20953172_ChIP-Seq_ESCs_Human1.03050745
152PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.01900327
153GF1B_26923725_Chip-Seq_HPCs_Mouse1.01684252
154SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.01398158
155FUS_26573619_Chip-Seq_HEK293_Human1.00335919
156EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.00190137
157P68_20966046_ChIP-Seq_HELA_Human1.00188481
158ZFX_18555785_Chip-Seq_ESCs_Mouse0.99806539
159SMRT_27268052_Chip-Seq_Bcells_Human0.99387847
160SPI1_26923725_Chip-Seq_HPCs_Mouse0.99275481
161FOXH1_21741376_ChIP-Seq_EPCs_Human0.97963807
162FOXA1_27270436_Chip-Seq_PROSTATE_Human0.97178053
163CDX2_19796622_ChIP-Seq_MESCs_Mouse0.94563883
164NFIB_24661679_ChIP-Seq_LUNG_Mouse0.94272397
165PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.94027575
166NFYB_21822215_ChIP-Seq_K562_Human0.93280810
167STAT3_18555785_ChIP-Seq_MESCs_Mouse0.92550609
168ER_23166858_ChIP-Seq_MCF-7_Human0.92223374
169SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.92089376
170FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91844966
171SOX9_26525672_Chip-Seq_HEART_Mouse0.91154223
172RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.90612855
173LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.90205078

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive6.13852565
2MP0001929_abnormal_gametogenesis5.62104450
3MP0003878_abnormal_ear_physiology4.80230831
4MP0005377_hearing/vestibular/ear_phenot4.80230831
5MP0008877_abnormal_DNA_methylation4.64112124
6MP0002210_abnormal_sex_determination3.78086652
7MP0002653_abnormal_ependyma_morphology3.43015469
8MP0002161_abnormal_fertility/fecundity3.31480386
9MP0001145_abnormal_male_reproductive3.14837899
10MP0001348_abnormal_lacrimal_gland2.80959057
11MP0000653_abnormal_sex_gland2.75981975
12MP0003718_maternal_effect2.18184892
13MP0001486_abnormal_startle_reflex2.05464001
14MP0005670_abnormal_white_adipose2.02088783
15MP0005410_abnormal_fertilization15.1803218
16MP0009046_muscle_twitch1.82322778
17MP0005623_abnormal_meninges_morphology1.81957438
18MP0004233_abnormal_muscle_weight1.81909052
19MP0000678_abnormal_parathyroid_gland1.77775518
20MP0001485_abnormal_pinna_reflex1.72995859
21MP0005451_abnormal_body_composition1.68848564
22MP0004742_abnormal_vestibular_system1.64796351
23MP0009053_abnormal_anal_canal1.57225252
24MP0002234_abnormal_pharynx_morphology1.53719275
25MP0005379_endocrine/exocrine_gland_phen1.52826782
26MP0008995_early_reproductive_senescence1.46008965
27MP0002132_abnormal_respiratory_system1.45565181
28MP0002735_abnormal_chemical_nociception1.43233047
29MP0001963_abnormal_hearing_physiology1.38127656
30MP0002249_abnormal_larynx_morphology1.34254479
31MP0002822_catalepsy1.33288601
32MP0003880_abnormal_central_pattern1.33123888
33MP0005367_renal/urinary_system_phenotyp1.30711003
34MP0000516_abnormal_urinary_system1.30711003
35MP0005310_abnormal_salivary_gland1.30528797
36MP0000026_abnormal_inner_ear1.28138128
37MP0008058_abnormal_DNA_repair1.27733813
38MP0001529_abnormal_vocalization1.26631613
39MP0001984_abnormal_olfaction1.25727100
40MP0008004_abnormal_stomach_pH1.24704113
41MP0005389_reproductive_system_phenotype1.18726428
42MP0001765_abnormal_ion_homeostasis1.18435143
43MP0002160_abnormal_reproductive_system1.16941998
44MP0000955_abnormal_spinal_cord1.10681729
45MP0000534_abnormal_ureter_morphology1.09079722
46MP0002272_abnormal_nervous_system1.05506902
47MP0003136_yellow_coat_color1.04926704
48MP0002127_abnormal_cardiovascular_syste1.03828917
49MP0005076_abnormal_cell_differentiation1.02217774
50MP0000049_abnormal_middle_ear0.99067874
51MP0002282_abnormal_trachea_morphology0.97053757
52MP0005248_abnormal_Harderian_gland0.96702111
53MP0002734_abnormal_mechanical_nocicepti0.95881217
54MP0001986_abnormal_taste_sensitivity0.92302954
55MP0005395_other_phenotype0.92162560
56MP0004510_myositis0.91044222
57MP0004085_abnormal_heartbeat0.88786197
58MP0001919_abnormal_reproductive_system0.87905076
59MP0005647_abnormal_sex_gland0.86097659
60MP0002138_abnormal_hepatobiliary_system0.85297183
61MP0003646_muscle_fatigue0.84652119
62MP0010094_abnormal_chromosome_stability0.82061355
63MP0002102_abnormal_ear_morphology0.81731065
64MP0002928_abnormal_bile_duct0.81660692
65MP0003119_abnormal_digestive_system0.81025127
66MP0006276_abnormal_autonomic_nervous0.77441976
67MP0001905_abnormal_dopamine_level0.76203453
68MP0002733_abnormal_thermal_nociception0.76177429
69MP0001970_abnormal_pain_threshold0.71978789
70MP0001501_abnormal_sleep_pattern0.71125288
71MP0004484_altered_response_of0.71043696
72MP0003786_premature_aging0.70098935
73MP0008789_abnormal_olfactory_epithelium0.69185780
74MP0001324_abnormal_eye_pigmentation0.66794611
75MP0002269_muscular_atrophy0.66679849
76MP0005551_abnormal_eye_electrophysiolog0.65351234
77MP0008057_abnormal_DNA_replication0.63699916
78MP0000566_synostosis0.63512241
79MP0005167_abnormal_blood-brain_barrier0.62448247
80MP0009764_decreased_sensitivity_to0.60138667
81MP0003137_abnormal_impulse_conducting0.59792535
82MP0002882_abnormal_neuron_morphology0.59689892
83MP0005636_abnormal_mineral_homeostasis0.58784673
84MP0001764_abnormal_homeostasis0.58758448
85MP0003633_abnormal_nervous_system0.55859441
86MP0002736_abnormal_nociception_after0.55429907
87MP0003699_abnormal_female_reproductive0.55323785
88MP0001293_anophthalmia0.55092337
89MP0001666_abnormal_nutrient_absorption0.54571997
90MP0010307_abnormal_tumor_latency0.54547483
91MP0001299_abnormal_eye_distance/0.54427254
92MP0002971_abnormal_brown_adipose0.54062105
93MP0004036_abnormal_muscle_relaxation0.53991997
94MP0005499_abnormal_olfactory_system0.53400129
95MP0005394_taste/olfaction_phenotype0.53400129
96MP0001119_abnormal_female_reproductive0.53320752
97MP0004145_abnormal_muscle_electrophysio0.52341898
98MP0003329_amyloid_beta_deposits0.48728181
99MP0002254_reproductive_system_inflammat0.48655652
100MP0002184_abnormal_innervation0.47587447
101MP0005253_abnormal_eye_physiology0.46056059
102MP0001968_abnormal_touch/_nociception0.45259010
103MP0005332_abnormal_amino_acid0.44691506
104MP0004019_abnormal_vitamin_homeostasis0.44042825
105MP0003861_abnormal_nervous_system0.43446445
106MP0003631_nervous_system_phenotype0.43081008
107MP0008569_lethality_at_weaning0.41744411
108MP0000778_abnormal_nervous_system0.41115582
109MP0003950_abnormal_plasma_membrane0.39199978
110MP0009115_abnormal_fat_cell0.35435710
111MP0005535_abnormal_body_temperature0.35209587
112MP0003115_abnormal_respiratory_system0.33532873
113MP0003879_abnormal_hair_cell0.33146241
114MP0002557_abnormal_social/conspecific_i0.31093790
115MP0009745_abnormal_behavioral_response0.30804836
116MP0008875_abnormal_xenobiotic_pharmacok0.30687302
117MP0005423_abnormal_somatic_nervous0.29883651
118MP0005666_abnormal_adipose_tissue0.29734097
119MP0002405_respiratory_system_inflammati0.29623622
120MP0003011_delayed_dark_adaptation0.29300740
121MP0001270_distended_abdomen0.29062060
122MP0003635_abnormal_synaptic_transmissio0.28528244
123MP0005174_abnormal_tail_pigmentation0.27902318
124MP0008961_abnormal_basal_metabolism0.27244064
125MP0001440_abnormal_grooming_behavior0.26109356
126MP0002693_abnormal_pancreas_physiology0.26068989
127MP0002572_abnormal_emotion/affect_behav0.25802292
128MP0004859_abnormal_synaptic_plasticity0.25587764
129MP0008007_abnormal_cellular_replicative0.25346505
130MP0004811_abnormal_neuron_physiology0.25269795
131MP0004808_abnormal_hematopoietic_stem0.24160585
132MP0002229_neurodegeneration0.24144787
133MP0001545_abnormal_hematopoietic_system0.24140486
134MP0005397_hematopoietic_system_phenotyp0.24140486
135MP0003959_abnormal_lean_body0.23764052
136MP0000604_amyloidosis0.23179488
137MP0002152_abnormal_brain_morphology0.23026647
138MP0003787_abnormal_imprinting0.22600471
139MP0004270_analgesia0.22011924
140MP0008872_abnormal_physiological_respon0.22001590
141MP0002063_abnormal_learning/memory/cond0.21475930
142MP0005319_abnormal_enzyme/_coenzyme0.20943905
143MP0003890_abnormal_embryonic-extraembry0.20660994
144MP0004043_abnormal_pH_regulation0.20442861
145MP0002133_abnormal_respiratory_system0.20437015
146MP0005388_respiratory_system_phenotype0.20437015
147MP0002064_seizures0.19864935
148MP0006036_abnormal_mitochondrial_physio0.19798245
149MP0004130_abnormal_muscle_cell0.19070584
150MP0005391_vision/eye_phenotype0.18777812
151MP0000313_abnormal_cell_death0.18647807
152MP0003953_abnormal_hormone_level0.18313154
153MP0003111_abnormal_nucleus_morphology0.16444656
154MP0002067_abnormal_sensory_capabilities0.16397047
155MP0002752_abnormal_somatic_nervous0.16367882
156MP0009785_altered_susceptibility_to0.16228150
157MP0001502_abnormal_circadian_rhythm0.15980896
158MP0000569_abnormal_digit_pigmentation0.15788815

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.22280535
2Abnormal respiratory motile cilium morphology (HP:0005938)9.02128180
3Abnormal respiratory epithelium morphology (HP:0012253)9.02128180
4Abnormal ciliary motility (HP:0012262)7.77058177
5Rhinitis (HP:0012384)7.50496996
6Severe visual impairment (HP:0001141)7.33740426
7Chronic bronchitis (HP:0004469)7.27826288
8Nasal polyposis (HP:0100582)6.24290149
9Infertility (HP:0000789)5.70109965
10Abnormality of the nasal mucosa (HP:0000433)5.07786504
11Attenuation of retinal blood vessels (HP:0007843)4.74693891
12Bony spicule pigmentary retinopathy (HP:0007737)4.55615058
13Bronchitis (HP:0012387)4.51200123
14Bronchiectasis (HP:0002110)4.37407570
15Abnormality of macular pigmentation (HP:0008002)4.14567644
16Bell-shaped thorax (HP:0001591)3.92040800
17Resting tremor (HP:0002322)3.85067259
18Recurrent sinusitis (HP:0011108)3.81421135
19Hypoplastic ischia (HP:0003175)3.81202178
20Hyperkalemia (HP:0002153)3.80353550
21Nephronophthisis (HP:0000090)3.69533029
22Abnormality of the ischium (HP:0003174)3.58424317
23Abnormal rod and cone electroretinograms (HP:0008323)3.52439988
24Male infertility (HP:0003251)3.50063179
25Medial flaring of the eyebrow (HP:0010747)3.44447766
26Aplasia/Hypoplasia of the earlobes (HP:0009906)3.41981772
27Enlarged epiphyses (HP:0010580)3.40514809
28Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.37054099
29Abnormal spermatogenesis (HP:0008669)3.35679118
30Aplasia/Hypoplasia of the pubic bone (HP:0009104)3.34235962
31Potter facies (HP:0002009)3.31789183
32Facial shape deformation (HP:0011334)3.31789183
33Tubulointerstitial nephritis (HP:0001970)3.25608895
34Progressive cerebellar ataxia (HP:0002073)3.24661012
35Progressive sensorineural hearing impairment (HP:0000408)3.24301698
36Recurrent otitis media (HP:0000403)3.24131702
37Cone-rod dystrophy (HP:0000548)3.20664231
38Hypoplasia of the thymus (HP:0000778)3.07153413
39Abnormality of the renal medulla (HP:0100957)2.92630514
40Hypoalphalipoproteinemia (HP:0003233)2.92227803
41Postural instability (HP:0002172)2.90054374
42Generalized aminoaciduria (HP:0002909)2.73017089
43Abnormal urine output (HP:0012590)2.72654198
44Congenital primary aphakia (HP:0007707)2.72513516
45Gait imbalance (HP:0002141)2.72413227
46Azoospermia (HP:0000027)2.70962303
47Recurrent bronchitis (HP:0002837)2.66782679
48Portal hypertension (HP:0001409)2.65995245
49Abnormality of the costochondral junction (HP:0000919)2.56109924
50Chronic sinusitis (HP:0011109)2.54494736
51Tongue fasciculations (HP:0001308)2.50443432
52Congenital malformation of the right heart (HP:0011723)2.47441829
53Double outlet right ventricle (HP:0001719)2.47441829
54Abnormal drinking behavior (HP:0030082)2.46902133
55Polydipsia (HP:0001959)2.46902133
56Abnormality of the hepatic vasculature (HP:0006707)2.45176190
57Abnormality of the parathyroid morphology (HP:0011766)2.40339835
58Abnormality of midbrain morphology (HP:0002418)2.40231787
59Molar tooth sign on MRI (HP:0002419)2.40231787
60Amelogenesis imperfecta (HP:0000705)2.39759827
61Truncal obesity (HP:0001956)2.36531438
62Abnormality of potassium homeostasis (HP:0011042)2.35619154
63Abnormality of the aortic arch (HP:0012303)2.33894002
64Abnormality of dental color (HP:0011073)2.33825952
65Congenital sensorineural hearing impairment (HP:0008527)2.32545809
66Nephrogenic diabetes insipidus (HP:0009806)2.31594634
67Muscle fibrillation (HP:0010546)2.31448808
68Renal dysplasia (HP:0000110)2.30357207
69Intellectual disability, moderate (HP:0002342)2.29051463
70Polyuria (HP:0000103)2.26624483
71Atonic seizures (HP:0010819)2.26027764
72Abnormality of the pubic bones (HP:0003172)2.23864407
73Vascular calcification (HP:0004934)2.21324556
74Poor coordination (HP:0002370)2.20184504
75Tubulointerstitial abnormality (HP:0001969)2.19420622
76Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.12798081
77Absent epiphyses (HP:0010577)2.12798081
78Occipital encephalocele (HP:0002085)2.12558060
79Osteomalacia (HP:0002749)2.12095579
80Renovascular hypertension (HP:0100817)2.11770420
81Tubular atrophy (HP:0000092)2.10836490
82Hypophosphatemic rickets (HP:0004912)2.06460190
83Recurrent corneal erosions (HP:0000495)2.06239037
84Weak cry (HP:0001612)2.01091475
85Vaginal atresia (HP:0000148)2.00044668
86Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.1305544
87Dynein arm defect of respiratory motile cilia (HP:0012255)12.9482287
88Absent/shortened dynein arms (HP:0200106)12.9482287
89Genital tract atresia (HP:0001827)1.98293052
90Cardiovascular calcification (HP:0011915)1.98198900
91Aplasia/Hypoplasia of the lens (HP:0008063)1.97631481
92Abnormality of the dental root (HP:0006486)1.95289835
93Taurodontia (HP:0000679)1.95289835
94Abnormality of permanent molar morphology (HP:0011071)1.95289835
95Asymmetric septal hypertrophy (HP:0001670)1.94885115
96Impulsivity (HP:0100710)1.93704168
97Pendular nystagmus (HP:0012043)1.93037790
98Hyponatremia (HP:0002902)1.91276797
99Insulin-resistant diabetes mellitus (HP:0000831)1.90099552
100Unilateral renal agenesis (HP:0000122)1.89987869
101Widely patent fontanelles and sutures (HP:0004492)1.86679101
102Epiphyseal dysplasia (HP:0002656)1.85425534
103Abnormality of molar morphology (HP:0011070)1.83830787
104Abnormality of molar (HP:0011077)1.83830787
105Progressive hearing impairment (HP:0001730)1.81429956
106Type 2 muscle fiber atrophy (HP:0003554)1.79520251
107Abnormality of the epiphysis of the femoral head (HP:0010574)1.78409064
108Nonprogressive disorder (HP:0003680)1.78134521
109Photophobia (HP:0000613)1.77628450
110Renal Fanconi syndrome (HP:0001994)1.77229289
111Abnormality of the dental pulp (HP:0006479)1.76333903
112Abnormality of saccadic eye movements (HP:0000570)1.75955452
113Optic nerve hypoplasia (HP:0000609)1.74841451
114Increased purine levels (HP:0004368)1.74359755
115Hyperuricemia (HP:0002149)1.74359755
116Mixed hearing impairment (HP:0000410)1.73488796
117Postaxial foot polydactyly (HP:0001830)1.72594936
118Glycosuria (HP:0003076)1.71668453
119Abnormality of urine glucose concentration (HP:0011016)1.71668453
120Fatigable weakness (HP:0003473)1.69631198
121Abnormality of the neuromuscular junction (HP:0003398)1.69631198
122Myokymia (HP:0002411)1.68773901
123Impaired smooth pursuit (HP:0007772)1.68529074
124Respiratory distress (HP:0002098)1.67041814
125Transposition of the great arteries (HP:0001669)1.66900929
126Abnormal connection of the cardiac segments (HP:0011545)1.66900929
127Abnormal ventriculo-arterial connection (HP:0011563)1.66900929
128Genetic anticipation (HP:0003743)1.66773277
129Stage 5 chronic kidney disease (HP:0003774)1.66598194
130Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.65707556
131Abnormality of dentin (HP:0010299)1.64641903
132Abnormality of ocular smooth pursuit (HP:0000617)1.64071473
133Heterotopia (HP:0002282)1.64015340
134Abnormality of the renal cortex (HP:0011035)1.61974291
135Congenital hepatic fibrosis (HP:0002612)1.61713376
136Postaxial hand polydactyly (HP:0001162)1.59892929
137Easy fatigability (HP:0003388)1.59222344
138Gonadotropin excess (HP:0000837)1.56852595
139Pancreatic fibrosis (HP:0100732)1.51389538
140Decreased central vision (HP:0007663)1.51107003
141Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.49273528
142Facial cleft (HP:0002006)1.48639726
143Muscle fiber atrophy (HP:0100295)1.47738978
144Chronic otitis media (HP:0000389)1.45090150
145Supernumerary spleens (HP:0009799)1.44569097
146Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.44465535
147Tubulointerstitial fibrosis (HP:0005576)1.44186552
148Papillary thyroid carcinoma (HP:0002895)1.43954681
149Fibular hypoplasia (HP:0003038)1.43897326
150Abnormality of renal excretion (HP:0011036)1.43820438
151Abnormality of the anterior horn cell (HP:0006802)1.42476977
152Degeneration of anterior horn cells (HP:0002398)1.42476977
153Spastic tetraparesis (HP:0001285)1.40991795
154Abnormality of the lower motor neuron (HP:0002366)1.40154561
155Hemiparesis (HP:0001269)1.39003019
156Absent frontal sinuses (HP:0002688)1.37580962
157Aplasia/Hypoplasia of the tongue (HP:0010295)1.35938104
158Short ribs (HP:0000773)1.35805288
159Cystic liver disease (HP:0006706)1.34616669
160Abnormal gallbladder physiology (HP:0012438)1.32141102
161Cholecystitis (HP:0001082)1.32141102
162Ventricular fibrillation (HP:0001663)1.31884303
163Short nail (HP:0001799)1.30095197
164True hermaphroditism (HP:0010459)1.29336928
165Hypoplasia of dental enamel (HP:0006297)1.29203343
166Chronic hepatic failure (HP:0100626)1.28980700
167Slow saccadic eye movements (HP:0000514)1.26807614
168Microglossia (HP:0000171)1.25506942
16911 pairs of ribs (HP:0000878)1.24656856
170Abnormality of renal resorption (HP:0011038)1.23761418
171Oculomotor apraxia (HP:0000657)1.23754306

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK39.53999845
2PDK49.53999845
3PDK26.16467287
4DDR24.56761374
5INSRR4.07830010
6TESK13.91018673
7PLK23.68082913
8MAP4K23.46709011
9PRKD33.06152204
10BRD42.60182497
11ICK2.45360240
12WNK42.04269962
13STK391.98685354
14PTK2B1.93728818
15PIK3CG1.53985123
16PNCK1.51399281
17CCNB11.23236273
18STK381.22738301
19PDK11.17697992
20MST1R1.14986625
21MAPK131.05860368
22LMTK21.04861345
23MAP3K41.02736204
24PLK41.02557001
25IRAK11.00113047
26EPHA40.99687718
27RIPK40.99337331
28MAP2K60.97211264
29MARK10.95339742
30CDK120.88316384
31CDK70.87359120
32NEK20.86617823
33WNK10.85941732
34TYRO30.85004872
35CAMK1G0.83866178
36MAP2K30.80654323
37RPS6KA20.80037158
38PRKAA20.79032192
39CASK0.78376500
40DYRK1B0.75933556
41MUSK0.74158811
42SIK20.71529851
43RPS6KA10.68892180
44TRIM280.67442346
45TAOK10.67203864
46UHMK10.66783429
47NTRK20.65868506
48TIE10.64483380
49TNIK0.64281698
50DYRK20.59484409
51CHEK20.56697421
52SGK4940.56563155
53SGK2230.56563155
54PASK0.55137759
55FRK0.54802668
56RPS6KA40.53945716
57KSR20.53909958
58ROCK10.52413225
59OXSR10.51325986
60EEF2K0.48753675
61PRKCE0.45685635
62PDPK10.45629239
63MAP2K70.45297336
64STK30.44046712
65MAP3K110.43427948
66BMPR1B0.42548670
67SGK20.40672906
68MAPKAPK30.40460591
69MAPK10.40200613
70CAMK10.39324054
71CAMKK10.39120516
72CDK30.39054852
73MAP2K40.38902481
74CHEK10.38575544
75CAMK40.37818955
76ADRBK20.37658634
77DYRK30.37602745
78PRKCB0.36638954
79YES10.36407481
80NTRK30.35599975
81WNK30.34184949
82CDK10.33783163
83CAMK2D0.32315866
84SGK10.32254680
85IRAK20.31941729
86MINK10.31916918
87FGFR10.31438044
88NEK60.31069844
89CAMK2G0.30837679
90CAMK1D0.30192906
91TESK20.30125907
92BRSK20.29409824
93CDK40.29400377
94STK38L0.28829565
95MAP3K80.27869980
96CAMK2B0.27452963
97MAP2K20.26930837
98SRPK10.26918081
99PINK10.26583103
100MAP3K10.26360679
101RPS6KC10.25377084
102RPS6KL10.25377084
103RPS6KA60.24810138
104PRKCG0.24102140
105MAPK150.24039949
106ZAK0.24034645
107GRK10.22599778
108MET0.21689860
109ATM0.21573691
110PRKACA0.20632710
111MAP3K30.19165515
112RPS6KB10.18808261
113MARK30.18701008
114CAMKK20.18089873
115PAK10.17269579
116TAOK20.17089164
117PRKCQ0.16012014
118ZAP700.15745793
119EGFR0.14418848
120WEE10.12909577
121PKN10.12623205
122RIPK10.12262406
123STK100.11862842
124BRSK10.11717846
125TTK0.11210338
126CDK150.09668466
127PDGFRB0.09058370
128MAP3K90.09025314
129MAPK100.08859298
130CDK180.08339247
131PRKG10.07818666
132SYK0.07086013
133BRAF0.06951910
134PRKG20.06895933
135PRKACG0.06795602
136GSK3B0.06772003
137AKT30.05619421
138CDK20.04488147
139ATR0.04437871
140TBK10.04365312
141PIM10.04230421
142MAPKAPK50.03864803
143PLK10.03568112
144CDK11A0.03447321
145CSNK1D0.03388476
146CAMK2A0.03203142
147PRKAA10.02933984
148MTOR0.02835517
149PRKCZ0.02684523
150CSNK2A20.02649584
151CDK140.02284247
152PRKCA0.02086767
153CDC70.02045748
154RPS6KB20.01741497
155PAK60.01631763
156MOS0.01486868
157GRK70.01413527
158STK110.01181875
159MAPK80.01164320

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000727.47387198
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.94808004
3Vitamin B6 metabolism_Homo sapiens_hsa007503.70445413
4Pyruvate metabolism_Homo sapiens_hsa006203.47030088
5Glycosaminoglycan degradation_Homo sapiens_hsa005313.15094435
6Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005123.10319005
7Butanoate metabolism_Homo sapiens_hsa006502.97525151
8Basal transcription factors_Homo sapiens_hsa030222.97201927
9Fatty acid biosynthesis_Homo sapiens_hsa000612.92785549
10Propanoate metabolism_Homo sapiens_hsa006402.92538631
11Glucagon signaling pathway_Homo sapiens_hsa049222.78629425
12Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.31499293
13Pentose phosphate pathway_Homo sapiens_hsa000302.30157404
14Oocyte meiosis_Homo sapiens_hsa041142.16766775
15Selenocompound metabolism_Homo sapiens_hsa004502.05872328
16Fanconi anemia pathway_Homo sapiens_hsa034601.88070401
17Glycerolipid metabolism_Homo sapiens_hsa005611.88040153
18Carbohydrate digestion and absorption_Homo sapiens_hsa049731.83430880
19alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.80489863
20Linoleic acid metabolism_Homo sapiens_hsa005911.69862531
21Amphetamine addiction_Homo sapiens_hsa050311.66563289
22Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.60468087
23Renin secretion_Homo sapiens_hsa049241.53596499
24PPAR signaling pathway_Homo sapiens_hsa033201.51021965
25Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.49179320
26Arginine and proline metabolism_Homo sapiens_hsa003301.45770109
27Huntingtons disease_Homo sapiens_hsa050161.45064722
28Mineral absorption_Homo sapiens_hsa049781.44005015
29Type II diabetes mellitus_Homo sapiens_hsa049301.42888114
30Cardiac muscle contraction_Homo sapiens_hsa042601.41015736
31Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.40813505
32Primary bile acid biosynthesis_Homo sapiens_hsa001201.40177872
33Dorso-ventral axis formation_Homo sapiens_hsa043201.40071606
34Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.34117657
35Fructose and mannose metabolism_Homo sapiens_hsa000511.32968522
36Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.31327255
37Collecting duct acid secretion_Homo sapiens_hsa049661.30978785
38Synaptic vesicle cycle_Homo sapiens_hsa047211.23085957
39Carbon metabolism_Homo sapiens_hsa012001.19896597
40Cysteine and methionine metabolism_Homo sapiens_hsa002701.19474612
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.18147490
42Nitrogen metabolism_Homo sapiens_hsa009101.17209788
43Phototransduction_Homo sapiens_hsa047441.16667079
44GABAergic synapse_Homo sapiens_hsa047271.14018861
45Inositol phosphate metabolism_Homo sapiens_hsa005621.13181864
46Insulin secretion_Homo sapiens_hsa049111.11937730
47Phosphatidylinositol signaling system_Homo sapiens_hsa040701.09271608
48Renin-angiotensin system_Homo sapiens_hsa046141.06970946
49Glycerophospholipid metabolism_Homo sapiens_hsa005641.05631545
50Phenylalanine metabolism_Homo sapiens_hsa003601.05151455
51Circadian entrainment_Homo sapiens_hsa047131.03322207
52Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.03160130
53Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.03129664
54Long-term potentiation_Homo sapiens_hsa047201.02487236
55Purine metabolism_Homo sapiens_hsa002300.98670160
56Salivary secretion_Homo sapiens_hsa049700.97707644
57Calcium signaling pathway_Homo sapiens_hsa040200.97033668
58Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.94568293
59Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.93250459
60Taste transduction_Homo sapiens_hsa047420.92879800
61Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.89267823
62Type I diabetes mellitus_Homo sapiens_hsa049400.88900370
63Gastric acid secretion_Homo sapiens_hsa049710.87499936
64Fatty acid degradation_Homo sapiens_hsa000710.86419108
65Bile secretion_Homo sapiens_hsa049760.84147720
66Antigen processing and presentation_Homo sapiens_hsa046120.80339510
67Caffeine metabolism_Homo sapiens_hsa002320.77101788
68Biosynthesis of amino acids_Homo sapiens_hsa012300.76490418
69Arginine biosynthesis_Homo sapiens_hsa002200.75222527
70Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.71497631
71Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.71306295
72Allograft rejection_Homo sapiens_hsa053300.71189575
73Sulfur metabolism_Homo sapiens_hsa009200.71033332
74cGMP-PKG signaling pathway_Homo sapiens_hsa040220.69017017
75mRNA surveillance pathway_Homo sapiens_hsa030150.69013763
76Autoimmune thyroid disease_Homo sapiens_hsa053200.68809615
77Estrogen signaling pathway_Homo sapiens_hsa049150.68558332
78Thyroid hormone synthesis_Homo sapiens_hsa049180.68341513
79Ether lipid metabolism_Homo sapiens_hsa005650.67359012
80Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.65857309
81Cholinergic synapse_Homo sapiens_hsa047250.64702041
82Fatty acid metabolism_Homo sapiens_hsa012120.63050226
83Retinol metabolism_Homo sapiens_hsa008300.60162794
84Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.58872948
85Serotonergic synapse_Homo sapiens_hsa047260.58871300
86Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.57737537
87Graft-versus-host disease_Homo sapiens_hsa053320.56218614
88cAMP signaling pathway_Homo sapiens_hsa040240.55010764
89Aldosterone synthesis and secretion_Homo sapiens_hsa049250.54929887
90Tight junction_Homo sapiens_hsa045300.54571574
91Viral myocarditis_Homo sapiens_hsa054160.54250167
92Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.53905820
93N-Glycan biosynthesis_Homo sapiens_hsa005100.53717633
94Adipocytokine signaling pathway_Homo sapiens_hsa049200.52962857
95Glutamatergic synapse_Homo sapiens_hsa047240.52457080
96Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.52323539
97Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.51860009
98beta-Alanine metabolism_Homo sapiens_hsa004100.51348642
99Pancreatic secretion_Homo sapiens_hsa049720.51301296
100Thyroid hormone signaling pathway_Homo sapiens_hsa049190.50035520
101RNA transport_Homo sapiens_hsa030130.48698367
102Glutathione metabolism_Homo sapiens_hsa004800.48356000
103Hedgehog signaling pathway_Homo sapiens_hsa043400.47259854
104Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.44986383
105Protein digestion and absorption_Homo sapiens_hsa049740.44859568
106Dopaminergic synapse_Homo sapiens_hsa047280.43863096
107Fat digestion and absorption_Homo sapiens_hsa049750.43129980
108ABC transporters_Homo sapiens_hsa020100.41774106
109Regulation of autophagy_Homo sapiens_hsa041400.41751259
110Morphine addiction_Homo sapiens_hsa050320.41537318
111Vibrio cholerae infection_Homo sapiens_hsa051100.41480008
112Chemical carcinogenesis_Homo sapiens_hsa052040.41162106
113Olfactory transduction_Homo sapiens_hsa047400.40769525
114Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.39516482
115Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.37906880
116Tyrosine metabolism_Homo sapiens_hsa003500.37719039
117Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.36073467
118Metabolic pathways_Homo sapiens_hsa011000.35663225
119Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.35340123
120Vascular smooth muscle contraction_Homo sapiens_hsa042700.34497906
121Nicotine addiction_Homo sapiens_hsa050330.34246091
122Legionellosis_Homo sapiens_hsa051340.33784595
123Central carbon metabolism in cancer_Homo sapiens_hsa052300.32844055
124Cocaine addiction_Homo sapiens_hsa050300.32792725
125Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.32065837
126Arachidonic acid metabolism_Homo sapiens_hsa005900.31441152
127Salmonella infection_Homo sapiens_hsa051320.30469509
128Influenza A_Homo sapiens_hsa051640.30113919
129Circadian rhythm_Homo sapiens_hsa047100.29096000
130Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.29032979
131Endocytosis_Homo sapiens_hsa041440.28890785
132Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.28644544
133Steroid biosynthesis_Homo sapiens_hsa001000.27684268
134Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.26928109
135Maturity onset diabetes of the young_Homo sapiens_hsa049500.25815139
136Oxytocin signaling pathway_Homo sapiens_hsa049210.25031745
137VEGF signaling pathway_Homo sapiens_hsa043700.24739315

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