EPRS

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species. Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)6.41658233
2nuclear pore organization (GO:0006999)6.33197650
3pore complex assembly (GO:0046931)4.75780578
4folic acid-containing compound biosynthetic process (GO:0009396)4.71838454
5DNA unwinding involved in DNA replication (GO:0006268)4.70811496
6IMP biosynthetic process (GO:0006188)4.51612686
7mitotic nuclear envelope disassembly (GO:0007077)4.42540571
8nuclear envelope disassembly (GO:0051081)4.15162132
9membrane disassembly (GO:0030397)4.15162132
10mitotic sister chromatid cohesion (GO:0007064)4.13544532
11nucleobase biosynthetic process (GO:0046112)4.06511311
12protein localization to kinetochore (GO:0034501)4.03786271
13regulation of translational fidelity (GO:0006450)3.96458788
14IMP metabolic process (GO:0046040)3.95182159
15regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.85952615
16DNA duplex unwinding (GO:0032508)3.84911407
17ribosome assembly (GO:0042255)3.83906615
18DNA geometric change (GO:0032392)3.82855149
19metaphase plate congression (GO:0051310)3.82423525
20mitotic metaphase plate congression (GO:0007080)3.82087052
21DNA replication-dependent nucleosome assembly (GO:0006335)3.81427564
22DNA replication-dependent nucleosome organization (GO:0034723)3.81427564
23Golgi transport vesicle coating (GO:0048200)3.74251296
24COPI coating of Golgi vesicle (GO:0048205)3.74251296
25formation of translation preinitiation complex (GO:0001731)3.72806397
26regulation of spindle organization (GO:0090224)3.70458955
27double-strand break repair via nonhomologous end joining (GO:0006303)3.68415159
28non-recombinational repair (GO:0000726)3.68415159
29DNA replication initiation (GO:0006270)3.64814621
30purine nucleobase biosynthetic process (GO:0009113)3.61060439
31regulation of posttranscriptional gene silencing (GO:0060147)3.56782942
32regulation of gene silencing by miRNA (GO:0060964)3.56782942
33regulation of gene silencing by RNA (GO:0060966)3.56782942
34positive regulation of chromosome segregation (GO:0051984)3.52839636
35mitotic chromosome condensation (GO:0007076)3.51628015
36regulation of mitotic spindle organization (GO:0060236)3.49469465
37kinetochore organization (GO:0051383)3.46131489
38regulation of histone H3-K9 methylation (GO:0051570)3.45356519
39L-serine metabolic process (GO:0006563)3.39064772
40regulation of translational elongation (GO:0006448)3.38269995
41telomere maintenance via recombination (GO:0000722)3.38000808
42heterochromatin organization (GO:0070828)3.35313396
43chromatin remodeling at centromere (GO:0031055)3.34347804
44protein localization to chromosome, centromeric region (GO:0071459)3.33775567
45negative regulation of histone methylation (GO:0031061)3.31717489
46tetrahydrofolate metabolic process (GO:0046653)3.31441201
47DNA strand elongation involved in DNA replication (GO:0006271)3.31245743
48regulation of RNA export from nucleus (GO:0046831)3.29373084
49sister chromatid segregation (GO:0000819)3.28000695
50somatic diversification of immune receptors via somatic mutation (GO:0002566)3.25693303
51somatic hypermutation of immunoglobulin genes (GO:0016446)3.25693303
52regulation of centriole replication (GO:0046599)3.24374726
53establishment of chromosome localization (GO:0051303)3.19817211
54regulation of helicase activity (GO:0051095)3.18500543
55DNA replication checkpoint (GO:0000076)3.18233741
56positive regulation of mitotic sister chromatid separation (GO:1901970)3.16637784
57positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.16637784
58positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.16637784
59* tRNA aminoacylation for protein translation (GO:0006418)3.16599276
60CENP-A containing nucleosome assembly (GO:0034080)3.16187198
61regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.15547576
62regulation of centrosome cycle (GO:0046605)3.14770927
63nuclear envelope organization (GO:0006998)3.14729377
64DNA strand elongation (GO:0022616)3.13803850
65pre-miRNA processing (GO:0031054)3.12166705
66negative regulation of DNA repair (GO:0045738)3.11295586
67chaperone-mediated protein complex assembly (GO:0051131)3.10701633
68DNA replication-independent nucleosome organization (GO:0034724)3.09713064
69DNA replication-independent nucleosome assembly (GO:0006336)3.09713064
70nucleobase-containing small molecule interconversion (GO:0015949)3.09307203
71protein complex localization (GO:0031503)3.08654170
72mitotic sister chromatid segregation (GO:0000070)3.06159025
73chromatin assembly (GO:0031497)3.05507708
74* amino acid activation (GO:0043038)3.05159540
75* tRNA aminoacylation (GO:0043039)3.05159540
76cellular protein complex localization (GO:0034629)3.04646859
77spindle checkpoint (GO:0031577)3.04312707
78protein K6-linked ubiquitination (GO:0085020)3.04302302
79ribosomal large subunit biogenesis (GO:0042273)3.04129076
80DNA topological change (GO:0006265)3.04089336
81RNA-dependent DNA replication (GO:0006278)3.02426691
82mitotic spindle checkpoint (GO:0071174)3.02110171
83DNA conformation change (GO:0071103)3.02106533
84regulation of mitotic metaphase/anaphase transition (GO:0030071)3.00961825
85dosage compensation (GO:0007549)3.00857453
86ribosome biogenesis (GO:0042254)3.00684806
87protein export from nucleus (GO:0006611)2.99833739
88establishment of viral latency (GO:0019043)2.99433935
89pteridine-containing compound biosynthetic process (GO:0042559)2.97273715
90spindle assembly checkpoint (GO:0071173)2.97186679
91regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.95439255
92attachment of spindle microtubules to kinetochore (GO:0008608)2.94419107
93establishment of integrated proviral latency (GO:0075713)2.94069189
94meiotic chromosome segregation (GO:0045132)2.93938884
95chromosome condensation (GO:0030261)2.93659671
96regulation of chromosome segregation (GO:0051983)2.93363746
97telomere maintenance via telomerase (GO:0007004)2.92765205
98regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.92502366
99mitotic spindle assembly checkpoint (GO:0007094)2.92465228
100negative regulation of chromosome segregation (GO:0051985)2.92074843
101telomere maintenance via telomere lengthening (GO:0010833)2.91685617
102maturation of SSU-rRNA (GO:0030490)2.91659540
103COPII vesicle coating (GO:0048208)2.91544101
104negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.91369753
105negative regulation of sister chromatid segregation (GO:0033046)2.91369753
106negative regulation of mitotic sister chromatid separation (GO:2000816)2.91369753
107negative regulation of mitotic sister chromatid segregation (GO:0033048)2.91369753
108regulation of DNA endoreduplication (GO:0032875)2.90431609
109chromosome segregation (GO:0007059)2.90364111
110regulation of translational termination (GO:0006449)2.85860412
111regulation of mitotic sister chromatid separation (GO:0010965)2.84192305
112regulation of mitotic sister chromatid segregation (GO:0033047)2.84192305
113regulation of sister chromatid segregation (GO:0033045)2.84192305
114paraxial mesoderm development (GO:0048339)2.83978541
115mitotic recombination (GO:0006312)2.83883847
116regulation of centrosome duplication (GO:0010824)2.83731411
117mRNA transport (GO:0051028)2.83264863
118chromatin assembly or disassembly (GO:0006333)2.81404708
119negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.80704337
120DNA ligation (GO:0006266)2.80330829
121histone exchange (GO:0043486)2.80089420
122telomere maintenance via semi-conservative replication (GO:0032201)2.79326855
123regulation of sister chromatid cohesion (GO:0007063)2.79029013
124glutamine metabolic process (GO:0006541)2.78396461
125nucleotide-excision repair, DNA gap filling (GO:0006297)2.78227487
126regulation of nucleobase-containing compound transport (GO:0032239)2.76241926
127ribonucleoprotein complex biogenesis (GO:0022613)2.76198604
128folic acid-containing compound metabolic process (GO:0006760)2.75001590

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.92357834
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.31399011
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.26017042
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.92020365
5FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.20783259
6* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.17150577
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.02285105
8MYC_19079543_ChIP-ChIP_MESCs_Mouse2.95645045
9* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.76472553
10SALL1_21062744_ChIP-ChIP_HESCs_Human2.75904809
11EGR1_19374776_ChIP-ChIP_THP-1_Human2.74063904
12* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.64438464
13NELFA_20434984_ChIP-Seq_ESCs_Mouse2.58425987
14RBPJ_22232070_ChIP-Seq_NCS_Mouse2.52801605
15KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.48953874
16EST1_17652178_ChIP-ChIP_JURKAT_Human2.44085048
17AR_21909140_ChIP-Seq_LNCAP_Human2.38581278
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.37489227
19E2F1_21310950_ChIP-Seq_MCF-7_Human2.25614405
20* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.21417337
21GABP_17652178_ChIP-ChIP_JURKAT_Human2.12505792
22MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.10343325
23* MYCN_18555785_ChIP-Seq_MESCs_Mouse2.09646320
24CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.06495336
25* ETS1_20019798_ChIP-Seq_JURKAT_Human2.04435426
26PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.00549452
27* ELK1_19687146_ChIP-ChIP_HELA_Human1.96983864
28* XRN2_22483619_ChIP-Seq_HELA_Human1.94724750
29MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.90193167
30* VDR_23849224_ChIP-Seq_CD4+_Human1.86166015
31POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.85715784
32YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.84753140
33* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.70614767
34E2F1_18555785_ChIP-Seq_MESCs_Mouse1.70559573
35DCP1A_22483619_ChIP-Seq_HELA_Human1.66109743
36FOXP3_21729870_ChIP-Seq_TREG_Human1.59987482
37PADI4_21655091_ChIP-ChIP_MCF-7_Human1.58632295
38ELF1_17652178_ChIP-ChIP_JURKAT_Human1.57363337
39NANOG_18555785_ChIP-Seq_MESCs_Mouse1.56220709
40* TTF2_22483619_ChIP-Seq_HELA_Human1.56157794
41HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.55451319
42* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.53311752
43POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.49009681
44TFEB_21752829_ChIP-Seq_HELA_Human1.45206654
45SOX2_18555785_ChIP-Seq_MESCs_Mouse1.44434667
46SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.44351979
47HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.44127711
48KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.43561600
49KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.43561600
50KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.43561600
51TP63_19390658_ChIP-ChIP_HaCaT_Human1.40849915
52STAT3_1855785_ChIP-Seq_MESCs_Mouse1.40536825
53GABP_19822575_ChIP-Seq_HepG2_Human1.40164738
54* KDM5A_27292631_Chip-Seq_BREAST_Human1.38787772
55ZNF263_19887448_ChIP-Seq_K562_Human1.36698967
56FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.36316569
57THAP11_20581084_ChIP-Seq_MESCs_Mouse1.29508415
58POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.27892056
59HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.27013777
60CIITA_25753668_ChIP-Seq_RAJI_Human1.24808776
61MYC_22102868_ChIP-Seq_BL_Human1.22373907
62ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.19990302
63NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.19989485
64* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.19571261
65PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.19298611
66SRF_21415370_ChIP-Seq_HL-1_Mouse1.17711566
67HOXB4_20404135_ChIP-ChIP_EML_Mouse1.14603556
68ESR1_15608294_ChIP-ChIP_MCF-7_Human1.14013796
69DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.13931575
70KLF4_18555785_ChIP-Seq_MESCs_Mouse1.12907097
71SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.11167511
72* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.11154511
73* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.10491961
74NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.09629836
75SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.08477731
76WT1_19549856_ChIP-ChIP_CCG9911_Human1.06432190
77TCF3_18692474_ChIP-Seq_MEFs_Mouse1.06181151
78* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.04524601
79E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.03926280
80* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.03713092
81* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.03224452
82HIF1A_21447827_ChIP-Seq_MCF-7_Human1.02564872
83ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.01377449
84SOX17_20123909_ChIP-Seq_XEN_Mouse1.01322689
85* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.00332005
86SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.98740376
87NANOG_16153702_ChIP-ChIP_HESCs_Human0.97426791
88ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.93929785
89ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.93231117
90CLOCK_20551151_ChIP-Seq_293T_Human0.93007571
91TCF3_18692474_ChIP-Seq_MESCs_Mouse0.92703364
92PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.92325044
93* CHD1_26751641_Chip-Seq_LNCaP_Human0.91944264
94NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.91938986
95* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.90513710
96NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.89723290
97EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.88574215
98DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.88572698
99MYC_18940864_ChIP-ChIP_HL60_Human0.88545417
100HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.88238682
101GATA4_21415370_ChIP-Seq_HL-1_Mouse0.88190536
102ERG_20887958_ChIP-Seq_HPC-7_Mouse0.86723620
103BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.86240740
104E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.85911873
105SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.85702063
106NANOG_21062744_ChIP-ChIP_HESCs_Human0.85227794
107NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.84597856
108SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.84065072
109SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.83747122
110MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.83692438
111* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.82407064
112* TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.82252037
113CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.77412357
114TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.75839611
115* SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.75627867
116HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.75508132
117TBX5_21415370_ChIP-Seq_HL-1_Mouse0.75068597
118YY1_21170310_ChIP-Seq_MESCs_Mouse0.74863927
119ELF5_23300383_ChIP-Seq_T47D_Human0.73425268
120CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.72529664
121KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.71982880

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching3.78256089
2MP0008057_abnormal_DNA_replication3.77322362
3MP0010094_abnormal_chromosome_stability3.74567731
4MP0004957_abnormal_blastocyst_morpholog3.32774584
5MP0003111_abnormal_nucleus_morphology3.29260994
6MP0010352_gastrointestinal_tract_polyps3.13151711
7MP0003077_abnormal_cell_cycle3.08632869
8MP0008058_abnormal_DNA_repair2.68875349
9MP0003123_paternal_imprinting2.63574920
10MP0008007_abnormal_cellular_replicative2.36797730
11MP0008438_abnormal_cutaneous_collagen2.31503445
12MP0001730_embryonic_growth_arrest2.28607672
13MP0008932_abnormal_embryonic_tissue2.27429932
14MP0003705_abnormal_hypodermis_morpholog2.18501721
15MP0010307_abnormal_tumor_latency2.07094189
16MP0000350_abnormal_cell_proliferation2.04384368
17MP0004197_abnormal_fetal_growth/weight/1.99595694
18MP0002877_abnormal_melanocyte_morpholog1.94278030
19MP0003121_genomic_imprinting1.86806149
20MP0008877_abnormal_DNA_methylation1.86393357
21MP0005076_abnormal_cell_differentiation1.84721466
22MP0003890_abnormal_embryonic-extraembry1.80953062
23MP0001672_abnormal_embryogenesis/_devel1.80032396
24MP0005380_embryogenesis_phenotype1.80032396
25MP0002084_abnormal_developmental_patter1.72483641
26MP0001697_abnormal_embryo_size1.68990113
27MP0000537_abnormal_urethra_morphology1.67951241
28MP0003806_abnormal_nucleotide_metabolis1.67556476
29MP0003984_embryonic_growth_retardation1.67333978
30MP0002088_abnormal_embryonic_growth/wei1.66481513
31MP0002009_preneoplasia1.65411389
32MP0005503_abnormal_tendon_morphology1.59754292
33MP0001661_extended_life_span1.58718265
34MP0002085_abnormal_embryonic_tissue1.57008106
35MP0003937_abnormal_limbs/digits/tail_de1.54465823
36MP0002086_abnormal_extraembryonic_tissu1.50346627
37MP0001293_anophthalmia1.48412768
38MP0003566_abnormal_cell_adhesion1.44505961
39MP0002080_prenatal_lethality1.44096748
40MP0003567_abnormal_fetal_cardiomyocyte1.41692883
41MP0005275_abnormal_skin_tensile1.40231584
42MP0003786_premature_aging1.38514769
43MP0010030_abnormal_orbit_morphology1.36540065
44MP0009703_decreased_birth_body1.30735010
45MP0009672_abnormal_birth_weight1.29335978
46MP0003941_abnormal_skin_development1.28855906
47MP0006054_spinal_hemorrhage1.28174181
48MP0009053_abnormal_anal_canal1.25584429
49MP0003950_abnormal_plasma_membrane1.25100107
50MP0000358_abnormal_cell_content/1.20460043
51MP0002396_abnormal_hematopoietic_system1.19601577
52MP0003119_abnormal_digestive_system1.18285057
53MP0005023_abnormal_wound_healing1.17358369
54MP0002111_abnormal_tail_morphology1.14666364
55MP0006035_abnormal_mitochondrial_morpho1.12829861
56MP0000432_abnormal_head_morphology1.11974600
57MP0004185_abnormal_adipocyte_glucose1.09908304
58MP0005501_abnormal_skin_physiology1.08363737
59MP0002697_abnormal_eye_size1.05193361
60MP0000428_abnormal_craniofacial_morphol1.04813009
61MP0003221_abnormal_cardiomyocyte_apopto1.02930316
62MP0004134_abnormal_chest_morphology1.02224381
63MP0002796_impaired_skin_barrier1.02069034
64MP0003755_abnormal_palate_morphology1.01283537
65MP0002938_white_spotting1.00521024
66MP0000733_abnormal_muscle_development0.99168713
67MP0003283_abnormal_digestive_organ0.97314866
68MP0001286_abnormal_eye_development0.95705059
69MP0001299_abnormal_eye_distance/0.95605885
70MP0000579_abnormal_nail_morphology0.94798010
71MP0002269_muscular_atrophy0.94611524
72MP0002060_abnormal_skin_morphology0.93888586
73MP0000313_abnormal_cell_death0.93766990
74MP0002092_abnormal_eye_morphology0.93266141
75MP0005623_abnormal_meninges_morphology0.92554834
76MP0005508_abnormal_skeleton_morphology0.91028110
77MP0003935_abnormal_craniofacial_develop0.89818443
78MP0001915_intracranial_hemorrhage0.89453834
79MP0003186_abnormal_redox_activity0.87323576
80MP0003787_abnormal_imprinting0.86690209
81MP0004808_abnormal_hematopoietic_stem0.86306322
82MP0001243_abnormal_dermal_layer0.85910878
83MP0004264_abnormal_extraembryonic_tissu0.84599024
84MP0003315_abnormal_perineum_morphology0.84489966
85MP0000377_abnormal_hair_follicle0.84290669
86MP0000627_abnormal_mammary_gland0.84044335
87MP0001881_abnormal_mammary_gland0.83487801
88MP0004233_abnormal_muscle_weight0.82828228
89MP0000647_abnormal_sebaceous_gland0.82661727
90MP0005187_abnormal_penis_morphology0.82545825
91MP0002210_abnormal_sex_determination0.80401513
92MP0005384_cellular_phenotype0.80227200
93MP0002896_abnormal_bone_mineralization0.79567354
94MP0000490_abnormal_crypts_of0.79272446
95MP0009250_abnormal_appendicular_skeleto0.78978319
96MP0000762_abnormal_tongue_morphology0.78768782
97MP0002019_abnormal_tumor_incidence0.78035988
98MP0005621_abnormal_cell_physiology0.77854838
99MP0003656_abnormal_erythrocyte_physiolo0.77721542
100MP0005408_hypopigmentation0.76802997
101MP0002114_abnormal_axial_skeleton0.76258256
102MP0010234_abnormal_vibrissa_follicle0.76106670
103MP0004133_heterotaxia0.75976828
104MP0004782_abnormal_surfactant_physiolog0.75231527
105MP0003718_maternal_effect0.74902579
106MP0001216_abnormal_epidermal_layer0.73235183
107MP0005171_absent_coat_pigmentation0.72679234
108MP0004272_abnormal_basement_membrane0.72413939
109MP0001145_abnormal_male_reproductive0.71729460
110MP0002109_abnormal_limb_morphology0.71000590
111MP0000516_abnormal_urinary_system0.70993949
112MP0005367_renal/urinary_system_phenotyp0.70993949
113MP0002282_abnormal_trachea_morphology0.70124732
114MP0003115_abnormal_respiratory_system0.69487546
115MP0002116_abnormal_craniofacial_bone0.68197998
116MP0001727_abnormal_embryo_implantation0.68068968
117MP0003385_abnormal_body_wall0.67771187
118MP0004147_increased_porphyrin_level0.67585209
119MP0000569_abnormal_digit_pigmentation0.66749915
120MP0002925_abnormal_cardiovascular_devel0.66669877
121MP0003942_abnormal_urinary_system0.66578517
122MP0009697_abnormal_copulation0.66547058
123MP0005220_abnormal_exocrine_pancreas0.65142800
124MP0002006_tumorigenesis0.64428660
125MP0005257_abnormal_intraocular_pressure0.64411194
126MP0009780_abnormal_chondrocyte_physiolo0.63845898
127MP0002234_abnormal_pharynx_morphology0.63194810
128MP0010678_abnormal_skin_adnexa0.63008096
129MP0005395_other_phenotype0.62735465
130MP0002160_abnormal_reproductive_system0.61827335

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of glycolysis (HP:0004366)3.69834162
2Cortical dysplasia (HP:0002539)3.50265644
3Ependymoma (HP:0002888)3.26929900
4Increased serum pyruvate (HP:0003542)3.22756032
5Medulloblastoma (HP:0002885)3.17794580
6Deviation of the thumb (HP:0009603)3.11360430
7Colon cancer (HP:0003003)3.05585800
8Birth length less than 3rd percentile (HP:0003561)3.02002898
9Abnormal gallbladder physiology (HP:0012438)2.93406124
10Cholecystitis (HP:0001082)2.93406124
11Volvulus (HP:0002580)2.90799971
12Chromsome breakage (HP:0040012)2.87119532
13Neoplasm of the oral cavity (HP:0100649)2.86861770
14Hypoplastic ischia (HP:0003175)2.85736330
15Abnormality of the preputium (HP:0100587)2.83274919
16Abnormality of the labia minora (HP:0012880)2.82651729
17Proximal placement of thumb (HP:0009623)2.81378761
18Metaphyseal cupping (HP:0003021)2.73871392
19Irregular epiphyses (HP:0010582)2.72974552
20Selective tooth agenesis (HP:0001592)2.67111295
21Ankyloglossia (HP:0010296)2.65218617
22Astrocytoma (HP:0009592)2.65055808
23Abnormality of the astrocytes (HP:0100707)2.65055808
24Biliary tract neoplasm (HP:0100574)2.64631386
25Upper limb muscle weakness (HP:0003484)2.62397318
26Rhabdomyosarcoma (HP:0002859)2.62171360
27Nephroblastoma (Wilms tumor) (HP:0002667)2.57646485
28Increased density of long bones (HP:0006392)2.50463384
29Glioma (HP:0009733)2.50458008
30Overlapping toe (HP:0001845)2.50228940
31Aplasia/Hypoplasia of the uvula (HP:0010293)2.48945702
32Microvesicular hepatic steatosis (HP:0001414)2.48584304
33Multiple enchondromatosis (HP:0005701)2.48231266
34Abnormality of the ischium (HP:0003174)2.46186068
35Missing ribs (HP:0000921)2.45189911
36Abnormality of the calcaneus (HP:0008364)2.43606664
37Chromosomal breakage induced by crosslinking agents (HP:0003221)2.41936044
38Protrusio acetabuli (HP:0003179)2.41487304
39Embryonal renal neoplasm (HP:0011794)2.40864811
40Degeneration of anterior horn cells (HP:0002398)2.38924743
41Abnormality of the anterior horn cell (HP:0006802)2.38924743
42Deep philtrum (HP:0002002)2.38431922
43Abnormality of methionine metabolism (HP:0010901)2.36655651
44Abnormality of chromosome stability (HP:0003220)2.35200300
45Duodenal stenosis (HP:0100867)2.34762862
46Small intestinal stenosis (HP:0012848)2.34762862
4711 pairs of ribs (HP:0000878)2.28990647
48Persistence of primary teeth (HP:0006335)2.27032796
49Carpal bone hypoplasia (HP:0001498)2.25203469
50Insidious onset (HP:0003587)2.19368006
51Termporal pattern (HP:0011008)2.19368006
52Epiphyseal dysplasia (HP:0002656)2.18479498
53Abnormal lung lobation (HP:0002101)2.16216335
54Cafe-au-lait spot (HP:0000957)2.15677032
55Pelvic girdle muscle weakness (HP:0003749)2.14570000
56Premature rupture of membranes (HP:0001788)2.13667484
57Long clavicles (HP:0000890)2.11075927
58Small epiphyses (HP:0010585)2.10829248
59Acute myeloid leukemia (HP:0004808)2.09784007
60Agnosia (HP:0010524)2.07623079
61Hypoplastic labia majora (HP:0000059)2.07066409
62Microglossia (HP:0000171)2.06106555
63Ankle contracture (HP:0006466)2.06003888
64Abnormality of the carotid arteries (HP:0005344)2.05228381
65Abnormality of oral frenula (HP:0000190)2.03664024
66Mild short stature (HP:0003502)2.02096909
67Progressive external ophthalmoplegia (HP:0000590)2.01083052
68Abnormality of homocysteine metabolism (HP:0010919)2.00688873
69Homocystinuria (HP:0002156)2.00688873
70Ectopic kidney (HP:0000086)2.00028354
71Absent radius (HP:0003974)1.98038613
72Progressive muscle weakness (HP:0003323)1.96708227
73Abnormality of the duodenum (HP:0002246)1.91649771
74Vitreoretinal degeneration (HP:0000655)1.91144541
75Abnormal biliary tract morphology (HP:0012440)1.90892149
76Abnormality of the labia majora (HP:0012881)1.90797159
77Patellar aplasia (HP:0006443)1.89069357
78Breech presentation (HP:0001623)1.88726565
79Stillbirth (HP:0003826)1.87157317
80Cupped ribs (HP:0000887)1.86810719
81Shoulder girdle muscle weakness (HP:0003547)1.86125362
82Insomnia (HP:0100785)1.86074979
83Glossoptosis (HP:0000162)1.86018934
84Relative macrocephaly (HP:0004482)1.85656628
85Neoplasm of the small intestine (HP:0100833)1.84733165
86Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.84648604
87Choanal atresia (HP:0000453)1.84613484
88Aplasia/Hypoplasia of the sternum (HP:0006714)1.84609583
89Neoplasm of the pancreas (HP:0002894)1.83842437
90Neoplasm of the rectum (HP:0100743)1.83645881
91Abnormal foot bone ossification (HP:0010675)1.83318924
92Freckling (HP:0001480)1.82699503
93Abnormal number of incisors (HP:0011064)1.82263932
94Ovarian neoplasm (HP:0100615)1.82126739
95Neoplasm of striated muscle (HP:0009728)1.81700327
96Sparse lateral eyebrow (HP:0005338)1.81126157
97Septate vagina (HP:0001153)1.81126112
98Abnormality of the proximal phalanges of the hand (HP:0009834)1.80271031
99Aplasia involving forearm bones (HP:0009822)1.80053963
100Absent forearm bone (HP:0003953)1.80053963
101Mesomelia (HP:0003027)1.78747105
102Abnormal vertebral ossification (HP:0100569)1.78617524
103Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.78192011
104Short 4th metacarpal (HP:0010044)1.78192011
105Cervical subluxation (HP:0003308)1.77690312
106Broad thumb (HP:0011304)1.77463551
107Increased nuchal translucency (HP:0010880)1.77365313
108Breast hypoplasia (HP:0003187)1.76484329
109Malignant gastrointestinal tract tumors (HP:0006749)1.76465091
110Gastrointestinal carcinoma (HP:0002672)1.76465091
111Abnormality of the umbilical cord (HP:0010881)1.76292154
112Abnormality of the hip-girdle musculature (HP:0001445)1.75910568
113Abnormality of the musculature of the pelvis (HP:0001469)1.75910568
114Entropion (HP:0000621)1.75860718
115Impulsivity (HP:0100710)1.74258555
116Spastic diplegia (HP:0001264)1.74227464
117Long eyelashes (HP:0000527)1.74090092
118Meckel diverticulum (HP:0002245)1.73538946
119Slender long bone (HP:0003100)1.71972043
120Aplasia/Hypoplasia of the patella (HP:0006498)1.71626345
121Trismus (HP:0000211)1.71063296
122Broad long bones (HP:0005622)1.70773417
123Neoplasm of the colon (HP:0100273)1.70529940
124Abnormalities of placenta or umbilical cord (HP:0001194)1.69990507
125Atresia of the external auditory canal (HP:0000413)1.69966711
126Cutaneous melanoma (HP:0012056)1.69524003
127Broad phalanx (HP:0006009)1.69138649
128Aplasia/hypoplasia of the humerus (HP:0006507)1.69062336
129Asymmetry of the thorax (HP:0001555)1.68109536
130Squamous cell carcinoma (HP:0002860)1.67904623
131Orthostatic hypotension (HP:0001278)1.67546578
132Secondary amenorrhea (HP:0000869)1.67503381
133Premature graying of hair (HP:0002216)1.66873710
134Broad phalanges of the hand (HP:0009768)1.66249996
135Oral leukoplakia (HP:0002745)1.64818812
136Shallow orbits (HP:0000586)1.63571252
137Short humerus (HP:0005792)1.62832203
138Limited elbow extension (HP:0001377)1.62610381
139Sloping forehead (HP:0000340)1.62362286
140Sandal gap (HP:0001852)1.62254351
141Papillary thyroid carcinoma (HP:0002895)1.61984730
142Amaurosis fugax (HP:0100576)1.61549463
143Myelodysplasia (HP:0002863)1.61012444
144Esophageal atresia (HP:0002032)1.60306986
145Arteriovenous malformation (HP:0100026)1.60296506
146Supernumerary ribs (HP:0005815)1.59972558
147Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.59970751
148Adenoma sebaceum (HP:0009720)1.59398990
149Angiofibromas (HP:0010615)1.59398990
150Abnormality of the ileum (HP:0001549)1.59127249
151Reticulocytopenia (HP:0001896)1.58980052
152Abnormality of the pons (HP:0007361)1.58600576
153Hypoplasia of the pons (HP:0012110)1.57346216
154Abnormality of sulfur amino acid metabolism (HP:0004339)1.56725785
155Megaloblastic anemia (HP:0001889)1.56577408
156Sensory axonal neuropathy (HP:0003390)1.55267827
157Dysmetric saccades (HP:0000641)1.54732504
158Short middle phalanx of the 5th finger (HP:0004220)1.53651478
159Abnormality of the intrinsic pathway (HP:0010989)1.53360256
160Postnatal microcephaly (HP:0005484)1.53304105
161Curly hair (HP:0002212)1.52979205
162Pancreatic islet-cell hyperplasia (HP:0004510)1.52960774
163Embryonal neoplasm (HP:0002898)1.51921830
164Abnormality of reticulocytes (HP:0004312)1.51438347
165Narrow face (HP:0000275)1.50627070
166Pterygium (HP:0001059)1.50361922
167Hand muscle atrophy (HP:0009130)1.46490254
168Abnormality of chromosome segregation (HP:0002916)1.46294186
169Horseshoe kidney (HP:0000085)1.45327343

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.04568838
2WEE13.17131051
3TSSK63.08283464
4CDK122.75350247
5EEF2K2.61395297
6PASK2.48247517
7TTK2.30601906
8EPHA22.29707876
9BRD42.26723505
10BRSK22.22563705
11SRPK12.20777720
12BUB12.07380663
13PLK32.07274955
14NEK22.06431317
15RPS6KB22.05483832
16MKNK11.99855159
17EIF2AK11.99780595
18NEK11.98402226
19MST1R1.93636533
20PNCK1.82563390
21ATR1.74595599
22ACVR1B1.68431999
23PLK11.62047172
24LATS11.56529139
25AURKB1.54522494
26PLK41.52381628
27SCYL21.48561292
28EIF2AK31.44893305
29PKN21.42887991
30* CHEK11.41865637
31ZAK1.41763026
32CDK71.37910829
33TRIM281.37600795
34AKT31.36433138
35MKNK21.35756669
36CLK11.33957441
37TTN1.31099230
38FLT31.28823997
39ATM1.23773600
40STK31.19726796
41CHEK21.17551510
42CDK41.12836521
43SMG11.12420698
44TLK11.12080518
45TAF11.11872960
46MET1.11287781
47CDK61.10205232
48MTOR1.08096523
49TGFBR11.07752059
50STK38L1.05019690
51DYRK31.04892925
52MAP3K81.04600157
53DDR21.02680253
54ALK0.99124577
55CCNB10.98873850
56CDK20.96866662
57VRK10.95922180
58STK160.93789523
59NME20.93531130
60FGFR10.93362213
61AURKA0.90722483
62RPS6KA40.89345295
63MAP3K100.88658078
64BRSK10.88276961
65MELK0.87016685
66RPS6KB10.85984849
67STK40.85928002
68STK100.85254621
69TRPM70.85218726
70CDK10.81803411
71CAMK1G0.81475315
72PDK20.79236340
73ICK0.78858843
74PBK0.78699251
75CSNK2A20.77594251
76NME10.75383168
77KSR10.73171401
78ERBB30.72810259
79VRK20.72121713
80CSNK1E0.71804851
81FRK0.70806931
82EIF2AK20.69856549
83MAP3K30.69729324
84PRKDC0.68844953
85PIM10.68472814
86PAK40.66386990
87PAK20.65172104
88PDGFRA0.64686186
89CSNK1D0.63726729
90CDK80.63549625
91BRAF0.61531918
92BCR0.61520950
93MAPKAPK30.60846186
94RAF10.60256838
95ERBB40.59217935
96RPS6KA50.57437382
97KSR20.54492732
98CSNK2A10.52765877
99CAMK1D0.52374315
100CHUK0.51144760
101PTK20.49290469
102* MAPK140.48158672
103PRKCI0.45621204
104MAP3K20.44853987
105IRAK30.43810852
106STK390.43748039
107YES10.41266552
108BMPR20.41095063
109AKT10.39252744
110MST40.38138272
111MAPK10.38104418
112PDK30.38062841
113PDK40.38062841
114LATS20.37739055
115PLK20.37550202
116GSK3A0.37471937
117NUAK10.37250999
118TESK20.36807804
119GSK3B0.36650383
120NEK90.36111132
121BMX0.35922544
122MAP3K90.35870850
123CDK30.35171390
124PTK60.34747270
125CSNK1A1L0.34224940
126AKT20.32001564
127FER0.31935107

Predicted pathways (KEGG)

RankGene SetZ-score
1One carbon pool by folate_Homo sapiens_hsa006704.02598506
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.89329493
3* Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009703.81050737
4Mismatch repair_Homo sapiens_hsa034303.68359569
5DNA replication_Homo sapiens_hsa030303.60823903
6RNA transport_Homo sapiens_hsa030133.42071638
7Spliceosome_Homo sapiens_hsa030402.96346413
8Non-homologous end-joining_Homo sapiens_hsa034502.78910569
9Cell cycle_Homo sapiens_hsa041102.70762831
10RNA polymerase_Homo sapiens_hsa030202.59694787
11Nucleotide excision repair_Homo sapiens_hsa034202.47747555
12Homologous recombination_Homo sapiens_hsa034402.32639933
13mRNA surveillance pathway_Homo sapiens_hsa030152.06576866
14Fanconi anemia pathway_Homo sapiens_hsa034602.03731487
15Base excision repair_Homo sapiens_hsa034102.01389166
16RNA degradation_Homo sapiens_hsa030181.98682000
17Proteasome_Homo sapiens_hsa030501.95571320
18Pyrimidine metabolism_Homo sapiens_hsa002401.72654786
19Basal transcription factors_Homo sapiens_hsa030221.67547088
20Selenocompound metabolism_Homo sapiens_hsa004501.66686793
21Pyruvate metabolism_Homo sapiens_hsa006201.62768897
22Systemic lupus erythematosus_Homo sapiens_hsa053221.55105308
23p53 signaling pathway_Homo sapiens_hsa041151.52524335
24Ribosome_Homo sapiens_hsa030101.48359052
25Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.43549471
26Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.32540741
27Viral carcinogenesis_Homo sapiens_hsa052031.30618394
28Propanoate metabolism_Homo sapiens_hsa006401.21328560
29MicroRNAs in cancer_Homo sapiens_hsa052061.20329131
30Epstein-Barr virus infection_Homo sapiens_hsa051691.12948930
31Caffeine metabolism_Homo sapiens_hsa002321.08270427
32Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.03198188
33Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.00858907
34Protein export_Homo sapiens_hsa030600.97813010
35Biosynthesis of amino acids_Homo sapiens_hsa012300.97031207
36ECM-receptor interaction_Homo sapiens_hsa045120.95530971
37TGF-beta signaling pathway_Homo sapiens_hsa043500.93297424
38HTLV-I infection_Homo sapiens_hsa051660.90174581
39Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.90071054
40Small cell lung cancer_Homo sapiens_hsa052220.88680904
41Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.87371077
42Hippo signaling pathway_Homo sapiens_hsa043900.86902613
43Basal cell carcinoma_Homo sapiens_hsa052170.85873353
44Purine metabolism_Homo sapiens_hsa002300.84277734
45Adherens junction_Homo sapiens_hsa045200.82271253
46Lysine degradation_Homo sapiens_hsa003100.81928531
47Antigen processing and presentation_Homo sapiens_hsa046120.80108258
48Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.80024356
49Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.79992051
50Drug metabolism - other enzymes_Homo sapiens_hsa009830.77832354
51Cysteine and methionine metabolism_Homo sapiens_hsa002700.75508066
52Oocyte meiosis_Homo sapiens_hsa041140.73630996
53Fatty acid elongation_Homo sapiens_hsa000620.72249085
54Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.69693916
55Arginine biosynthesis_Homo sapiens_hsa002200.68008166
56Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.67503407
57Prostate cancer_Homo sapiens_hsa052150.65862702
58Thyroid cancer_Homo sapiens_hsa052160.65407767
59Cyanoamino acid metabolism_Homo sapiens_hsa004600.63738304
60Hedgehog signaling pathway_Homo sapiens_hsa043400.63284163
61Central carbon metabolism in cancer_Homo sapiens_hsa052300.62924575
62Bladder cancer_Homo sapiens_hsa052190.60526303
63Steroid biosynthesis_Homo sapiens_hsa001000.60508873
64Transcriptional misregulation in cancer_Homo sapiens_hsa052020.59684755
65Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.59419567
66Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.58873157
67Alcoholism_Homo sapiens_hsa050340.58342167
68Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.56853802
69Fatty acid metabolism_Homo sapiens_hsa012120.56078247
70Vitamin B6 metabolism_Homo sapiens_hsa007500.55723243
71Carbon metabolism_Homo sapiens_hsa012000.54123797
72Focal adhesion_Homo sapiens_hsa045100.53616618
73Legionellosis_Homo sapiens_hsa051340.52805486
74Herpes simplex infection_Homo sapiens_hsa051680.52381940
75Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.51317847
76Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.51123655
77Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.50960927
78PI3K-Akt signaling pathway_Homo sapiens_hsa041510.50832190
79Proteoglycans in cancer_Homo sapiens_hsa052050.50432295
80Tight junction_Homo sapiens_hsa045300.50110648
81Maturity onset diabetes of the young_Homo sapiens_hsa049500.47387583
82Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.47258168
83mTOR signaling pathway_Homo sapiens_hsa041500.45847056
84N-Glycan biosynthesis_Homo sapiens_hsa005100.44816066
85Colorectal cancer_Homo sapiens_hsa052100.43695349
86Chronic myeloid leukemia_Homo sapiens_hsa052200.43158028
87Pathways in cancer_Homo sapiens_hsa052000.42989349
88Protein digestion and absorption_Homo sapiens_hsa049740.39637839
89Wnt signaling pathway_Homo sapiens_hsa043100.38660233
90Pancreatic cancer_Homo sapiens_hsa052120.38587970
91Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.37075883
922-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.36325286
93Melanoma_Homo sapiens_hsa052180.36149777
94HIF-1 signaling pathway_Homo sapiens_hsa040660.34945119
95Sulfur metabolism_Homo sapiens_hsa009200.34892999
96* Metabolic pathways_Homo sapiens_hsa011000.32589285
97Arginine and proline metabolism_Homo sapiens_hsa003300.32564862
98Galactose metabolism_Homo sapiens_hsa000520.32303391
99Glutathione metabolism_Homo sapiens_hsa004800.31625813
100Fatty acid biosynthesis_Homo sapiens_hsa000610.31442503
101Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.30843228
102Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.29975286
103* Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.29316938
104Endometrial cancer_Homo sapiens_hsa052130.28755926
105Pentose phosphate pathway_Homo sapiens_hsa000300.28380659
106FoxO signaling pathway_Homo sapiens_hsa040680.27736451
107Apoptosis_Homo sapiens_hsa042100.27508564
108Huntingtons disease_Homo sapiens_hsa050160.27374474
109Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.26985681
110Glioma_Homo sapiens_hsa052140.26794638
111NF-kappa B signaling pathway_Homo sapiens_hsa040640.24959680
112Viral myocarditis_Homo sapiens_hsa054160.23875864
113Notch signaling pathway_Homo sapiens_hsa043300.22857478
114Non-small cell lung cancer_Homo sapiens_hsa052230.22581774
115AMPK signaling pathway_Homo sapiens_hsa041520.22431190
116Thyroid hormone signaling pathway_Homo sapiens_hsa049190.21633923
117Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.21463349
118Thyroid hormone synthesis_Homo sapiens_hsa049180.21414645
119Folate biosynthesis_Homo sapiens_hsa007900.20505563
120Insulin signaling pathway_Homo sapiens_hsa049100.20352613
121Renal cell carcinoma_Homo sapiens_hsa052110.20283974
122Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.20266009
123Vibrio cholerae infection_Homo sapiens_hsa051100.19525208
124Fructose and mannose metabolism_Homo sapiens_hsa000510.18834890

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