EPHA10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al., 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph receptors and ephrins. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.98679442
2vocalization behavior (GO:0071625)5.43760473
3positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.41494858
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.05578710
5ionotropic glutamate receptor signaling pathway (GO:0035235)5.00812733
6behavioral response to nicotine (GO:0035095)5.00631419
7protein localization to synapse (GO:0035418)5.00550632
8synaptic vesicle exocytosis (GO:0016079)4.94219119
9synaptic vesicle docking involved in exocytosis (GO:0016081)4.93655281
10positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.71146888
11synaptic vesicle maturation (GO:0016188)4.70621206
12glutamate receptor signaling pathway (GO:0007215)4.69667391
13synaptic transmission, glutamatergic (GO:0035249)4.67553128
14regulation of glutamate receptor signaling pathway (GO:1900449)4.67364559
15glutamate secretion (GO:0014047)4.63009035
16regulation of synaptic vesicle exocytosis (GO:2000300)4.59000541
17locomotory exploration behavior (GO:0035641)4.53142057
18G-protein coupled glutamate receptor signaling pathway (GO:0007216)4.47887917
19neuron-neuron synaptic transmission (GO:0007270)4.36578471
20regulation of synaptic vesicle transport (GO:1902803)4.25862005
21regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.25311306
22neuron cell-cell adhesion (GO:0007158)4.22299929
23response to pheromone (GO:0019236)4.22198897
24startle response (GO:0001964)4.20210459
25regulation of neuronal synaptic plasticity (GO:0048168)4.02122553
26neurotransmitter-gated ion channel clustering (GO:0072578)3.98481296
27neuronal action potential propagation (GO:0019227)3.95933147
28glycine transport (GO:0015816)3.94162204
29positive regulation of synapse maturation (GO:0090129)3.89615960
30regulation of synapse maturation (GO:0090128)3.80774914
31long-term memory (GO:0007616)3.79903304
32gamma-aminobutyric acid signaling pathway (GO:0007214)3.78853750
33regulation of long-term neuronal synaptic plasticity (GO:0048169)3.75568138
34neurotransmitter secretion (GO:0007269)3.69628600
35regulation of excitatory postsynaptic membrane potential (GO:0060079)3.69298609
36transmission of nerve impulse (GO:0019226)3.67732523
37dendritic spine morphogenesis (GO:0060997)3.63586140
38postsynaptic membrane organization (GO:0001941)3.61959905
39negative regulation of synaptic transmission, GABAergic (GO:0032229)3.61745753
40regulation of postsynaptic membrane potential (GO:0060078)3.61703456
41gamma-aminobutyric acid transport (GO:0015812)3.60023295
42regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.58946250
43righting reflex (GO:0060013)3.55209705
44positive regulation of membrane potential (GO:0045838)3.53985778
45regulation of vesicle fusion (GO:0031338)3.51989908
46exploration behavior (GO:0035640)3.51581110
47L-fucose catabolic process (GO:0042355)3.50537776
48fucose catabolic process (GO:0019317)3.50537776
49L-fucose metabolic process (GO:0042354)3.50537776
50membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.47197289
51regulation of neurotransmitter secretion (GO:0046928)3.46901699
52regulation of synaptic plasticity (GO:0048167)3.46296935
53pyrimidine nucleobase catabolic process (GO:0006208)3.46096152
54nucleobase catabolic process (GO:0046113)3.45628872
55behavioral defense response (GO:0002209)3.41971100
56behavioral fear response (GO:0001662)3.41971100
57membrane depolarization during action potential (GO:0086010)3.39364611
58neurotransmitter transport (GO:0006836)3.37752903
59dendritic spine organization (GO:0097061)3.37706972
60cellular potassium ion homeostasis (GO:0030007)3.37699989
61neuron recognition (GO:0008038)3.37560230
62neuronal action potential (GO:0019228)3.36351976
63regulation of synaptic transmission, glutamatergic (GO:0051966)3.34947995
64regulation of neurotransmitter transport (GO:0051588)3.32909540
65positive regulation of neurotransmitter secretion (GO:0001956)3.31519689
66synaptic vesicle endocytosis (GO:0048488)3.31053605
67central nervous system projection neuron axonogenesis (GO:0021952)3.30311112
68proline transport (GO:0015824)3.28830497
69positive regulation of synaptic transmission, GABAergic (GO:0032230)3.24845849
70positive regulation of neurotransmitter transport (GO:0051590)3.24194920
71long-term synaptic potentiation (GO:0060291)3.22999883
72membrane depolarization (GO:0051899)3.21467356
73cellular ketone body metabolic process (GO:0046950)3.19744450
74negative regulation of cytosolic calcium ion concentration (GO:0051481)3.19599724
75behavioral response to ethanol (GO:0048149)3.17328851
76learning (GO:0007612)3.16999486
77behavioral response to cocaine (GO:0048148)3.14454435
78regulation of guanylate cyclase activity (GO:0031282)3.13341642
79cerebellar Purkinje cell differentiation (GO:0021702)3.12644794
80fear response (GO:0042596)3.12638977
81response to histamine (GO:0034776)3.12090448
82synaptic transmission (GO:0007268)3.10102944
83negative regulation of amino acid transport (GO:0051956)3.09314418
84L-amino acid import (GO:0043092)3.09291391
85dendrite morphogenesis (GO:0048813)3.08832904
86positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.08819844
87regulation of calcium ion-dependent exocytosis (GO:0017158)3.08668616
88axonal fasciculation (GO:0007413)3.06357193
89negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.05413311
90presynaptic membrane assembly (GO:0097105)3.04622920
91dendrite development (GO:0016358)3.04310635
92calcium ion import (GO:0070509)3.01756089
93regulation of synaptic transmission (GO:0050804)3.01391978
94membrane hyperpolarization (GO:0060081)3.01231245
95negative regulation of calcium ion-dependent exocytosis (GO:0045955)3.01226006
96response to auditory stimulus (GO:0010996)3.01147270
97positive regulation of fibroblast migration (GO:0010763)3.00959184
98regulation of synapse structural plasticity (GO:0051823)2.98718726
99innervation (GO:0060384)2.97494843
100primary amino compound metabolic process (GO:1901160)2.95913854
101associative learning (GO:0008306)2.94280752
102piRNA metabolic process (GO:0034587)2.93834545
103regulation of dendritic spine morphogenesis (GO:0061001)2.93248786
104regulation of neurotransmitter levels (GO:0001505)2.92894171
105positive regulation of dendritic spine morphogenesis (GO:0061003)2.92663074
106regulation of glutamate secretion (GO:0014048)2.91740202
107detection of light stimulus involved in sensory perception (GO:0050962)2.91533855
108detection of light stimulus involved in visual perception (GO:0050908)2.91533855
109cellular sodium ion homeostasis (GO:0006883)2.91422256
110cellular response to ATP (GO:0071318)2.90745904
111alanine transport (GO:0032328)2.88767098
112regulation of action potential (GO:0098900)2.88133766
113neuromuscular process controlling posture (GO:0050884)2.87926955
114synapse assembly (GO:0007416)2.87522176
115adult walking behavior (GO:0007628)2.87130958
116cAMP catabolic process (GO:0006198)2.87021432
117presynaptic membrane organization (GO:0097090)2.86672965
118ketone body metabolic process (GO:1902224)2.86378477
119detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.86136577
120positive regulation of guanylate cyclase activity (GO:0031284)2.85153762
121auditory behavior (GO:0031223)2.84717984
122protein polyglutamylation (GO:0018095)2.83781405
123positive regulation of synaptic transmission (GO:0050806)2.83303881
124positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.82363119
125indole-containing compound catabolic process (GO:0042436)2.80634383
126indolalkylamine catabolic process (GO:0046218)2.80634383
127tryptophan catabolic process (GO:0006569)2.80634383
128indolalkylamine metabolic process (GO:0006586)2.79618391
129neuromuscular synaptic transmission (GO:0007274)2.77962491
130serotonin metabolic process (GO:0042428)2.70923817
131purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.70777944
1323-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.70777944
133multicellular organism reproduction (GO:0032504)2.67913626
134action potential (GO:0001508)2.64697739
135urinary tract smooth muscle contraction (GO:0014848)2.63268298
136indole-containing compound metabolic process (GO:0042430)2.61656090
137spinal cord motor neuron differentiation (GO:0021522)2.60665948
138reflex (GO:0060004)2.60255461
139DNA methylation involved in gamete generation (GO:0043046)2.60159833
140sperm motility (GO:0030317)2.59108212
141neurotransmitter metabolic process (GO:0042133)2.57348619
142regulation of neurotransmitter uptake (GO:0051580)2.55860879
143axoneme assembly (GO:0035082)2.55394266
144kynurenine metabolic process (GO:0070189)2.55382268
145calcium ion-dependent exocytosis (GO:0017156)2.53907777
146adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.53038398
147neurotransmitter catabolic process (GO:0042135)2.52255277
148exogenous drug catabolic process (GO:0042738)2.51754118
149cornea development in camera-type eye (GO:0061303)2.51500653
150auditory receptor cell stereocilium organization (GO:0060088)2.51333897
151glycerophospholipid catabolic process (GO:0046475)2.49790702
152cochlea development (GO:0090102)2.45635916
153peristalsis (GO:0030432)2.45604853
154nephron epithelium morphogenesis (GO:0072088)2.45566335
155nephron tubule morphogenesis (GO:0072078)2.45566335
156cell migration in hindbrain (GO:0021535)2.45353402
157phosphatidylinositol acyl-chain remodeling (GO:0036149)2.45143078
158retinal cone cell development (GO:0046549)2.44213838
159positive regulation of sodium ion transmembrane transporter activity (GO:2000651)2.43748523
160synaptic transmission, cholinergic (GO:0007271)2.41798930
161negative regulation of telomere maintenance (GO:0032205)2.41135948
162regulation of microtubule-based movement (GO:0060632)2.40878666
163nucleotide transmembrane transport (GO:1901679)2.38862373
164sulfation (GO:0051923)2.37681603
165C4-dicarboxylate transport (GO:0015740)2.35296600

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.88196996
2GBX2_23144817_ChIP-Seq_PC3_Human3.98041263
3JARID2_20064375_ChIP-Seq_MESCs_Mouse2.94107033
4* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.89342525
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.87353636
6SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.62268423
7* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.56610558
8EED_16625203_ChIP-ChIP_MESCs_Mouse2.55254689
9* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.50666934
10* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.50666934
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.48268532
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.48169623
13* REST_21632747_ChIP-Seq_MESCs_Mouse2.38721632
14* DROSHA_22980978_ChIP-Seq_HELA_Human2.32557804
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.29601884
16* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.26462310
17MTF2_20144788_ChIP-Seq_MESCs_Mouse2.24666082
18* EZH2_27294783_Chip-Seq_ESCs_Mouse2.20678450
19RNF2_27304074_Chip-Seq_ESCs_Mouse2.16385372
20* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.15977031
21TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.11521096
22GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.85307145
23SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.82561689
24GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.79479911
25RARB_27405468_Chip-Seq_BRAIN_Mouse1.78844854
26CTBP2_25329375_ChIP-Seq_LNCAP_Human1.76026372
27* REST_18959480_ChIP-ChIP_MESCs_Mouse1.74760724
28* IKZF1_21737484_ChIP-ChIP_HCT116_Human1.73335256
29AR_21572438_ChIP-Seq_LNCaP_Human1.72030090
30CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.71360487
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.70658241
32ZFP57_27257070_Chip-Seq_ESCs_Mouse1.70441040
33* CBX2_27304074_Chip-Seq_ESCs_Mouse1.66983766
34ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.66524513
35BMI1_23680149_ChIP-Seq_NPCS_Mouse1.64834896
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.63993943
37SMAD4_21799915_ChIP-Seq_A2780_Human1.60541955
38TAF15_26573619_Chip-Seq_HEK293_Human1.56149708
39PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.55507470
40RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.52885528
41P300_19829295_ChIP-Seq_ESCs_Human1.49266340
42BCAT_22108803_ChIP-Seq_LS180_Human1.47591399
43SMAD3_21741376_ChIP-Seq_EPCs_Human1.43716841
44* EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.42510228
45RNF2_27304074_Chip-Seq_NSC_Mouse1.40731342
46VDR_22108803_ChIP-Seq_LS180_Human1.40402471
47IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.39923445
48CBP_20019798_ChIP-Seq_JUKART_Human1.39923445
49CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36547077
50SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.35297601
51TP53_22573176_ChIP-Seq_HFKS_Human1.34588322
52* ERA_21632823_ChIP-Seq_H3396_Human1.31686053
53STAT3_23295773_ChIP-Seq_U87_Human1.30992355
54ETV2_25802403_ChIP-Seq_MESCs_Mouse1.30622803
55PIAS1_25552417_ChIP-Seq_VCAP_Human1.30363944
56AR_25329375_ChIP-Seq_VCAP_Human1.30064653
57SMAD_19615063_ChIP-ChIP_OVARY_Human1.28902865
58MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.28554459
59FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.28285813
60NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.26636021
61EWS_26573619_Chip-Seq_HEK293_Human1.26319477
62EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.26303888
63RING1B_27294783_Chip-Seq_ESCs_Mouse1.25789567
64GATA3_21878914_ChIP-Seq_MCF-7_Human1.23020562
65NCOR_22424771_ChIP-Seq_293T_Human1.22076242
66TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.20741274
67TOP2B_26459242_ChIP-Seq_MCF-7_Human1.20147072
68TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.20035723
69* TCF4_23295773_ChIP-Seq_U87_Human1.19412928
70POU3F2_20337985_ChIP-ChIP_501MEL_Human1.19263733
71ZNF274_21170338_ChIP-Seq_K562_Hela1.19147578
72CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.18515203
73NANOG_18555785_Chip-Seq_ESCs_Mouse1.17882642
74SOX2_21211035_ChIP-Seq_LN229_Gbm1.17859418
75EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.17748095
76GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.16451167
77MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.15261190
78P53_22127205_ChIP-Seq_FIBROBLAST_Human1.15055965
79RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.13218448
80VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.12615933
81HOXB7_26014856_ChIP-Seq_BT474_Human1.11640531
82TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10362106
83POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.10362106
84FOXA1_25329375_ChIP-Seq_VCAP_Human1.09614974
85FOXA1_27270436_Chip-Seq_PROSTATE_Human1.09614974
86* AR_19668381_ChIP-Seq_PC3_Human1.08767562
87E2F1_18555785_Chip-Seq_ESCs_Mouse1.07934372
88RUNX2_22187159_ChIP-Seq_PCA_Human1.07703866
89* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.06348705
90TCF4_22108803_ChIP-Seq_LS180_Human1.06290228
91MYC_19829295_ChIP-Seq_ESCs_Human1.05906236
92SUZ12_27294783_Chip-Seq_NPCs_Mouse1.05449180
93FUS_26573619_Chip-Seq_HEK293_Human1.05197573
94ER_23166858_ChIP-Seq_MCF-7_Human1.04909524
95UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.04753458
96IGF1R_20145208_ChIP-Seq_DFB_Human1.04691988
97* OCT4_20526341_ChIP-Seq_ESCs_Human1.04464199
98PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.04347103
99* CTCF_27219007_Chip-Seq_Bcells_Human1.04318522
100* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.04288492
101FLI1_27457419_Chip-Seq_LIVER_Mouse1.03954987
102EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.03705244
103P53_22387025_ChIP-Seq_ESCs_Mouse1.03550118
104NR3C1_21868756_ChIP-Seq_MCF10A_Human1.03520029
105OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.03267054
106TP53_18474530_ChIP-ChIP_U2OS_Human1.03161867
107SMAD3_21741376_ChIP-Seq_HESCs_Human1.02681321
108E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.02065184
109ARNT_22903824_ChIP-Seq_MCF-7_Human1.01767078
110* TAF2_19829295_ChIP-Seq_ESCs_Human1.01409589
111TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.01358506
112PCGF2_27294783_Chip-Seq_ESCs_Mouse1.01342774
113* RING1B_27294783_Chip-Seq_NPCs_Mouse1.01118115
114PRDM14_20953172_ChIP-Seq_ESCs_Human1.01039589
115CMYC_18555785_Chip-Seq_ESCs_Mouse1.01012600
116ERG_21242973_ChIP-ChIP_JURKAT_Human1.00107129
117* SMAD4_21741376_ChIP-Seq_EPCs_Human1.00095410
118MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.99241897
119NANOG_19829295_ChIP-Seq_ESCs_Human0.99183455
120SOX2_19829295_ChIP-Seq_ESCs_Human0.99183455
121AHR_22903824_ChIP-Seq_MCF-7_Human0.98805841
122AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.98707667
123P53_21459846_ChIP-Seq_SAOS-2_Human0.98700404
124TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.98674090
125CDX2_19796622_ChIP-Seq_MESCs_Mouse0.97556741
126* CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.97537471
127YAP1_20516196_ChIP-Seq_MESCs_Mouse0.97420458
128MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.96900861
129CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.96473516
130NFE2_27457419_Chip-Seq_LIVER_Mouse0.96292223
131PCGF2_27294783_Chip-Seq_NPCs_Mouse0.95303799
132SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.94960222
133MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.94959293
134SUZ12_18555785_Chip-Seq_ESCs_Mouse0.94756080
135TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94628209

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.00633190
2MP0003880_abnormal_central_pattern5.21430350
3MP0003635_abnormal_synaptic_transmissio3.86305991
4MP0009745_abnormal_behavioral_response3.42642307
5MP0005423_abnormal_somatic_nervous3.23110239
6MP0002063_abnormal_learning/memory/cond3.10200111
7MP0002064_seizures2.94308569
8MP0001968_abnormal_touch/_nociception2.93087786
9MP0009046_muscle_twitch2.90015664
10MP0002572_abnormal_emotion/affect_behav2.72945006
11MP0001486_abnormal_startle_reflex2.69514013
12MP0004270_analgesia2.49847419
13MP0002272_abnormal_nervous_system2.49452649
14MP0002735_abnormal_chemical_nociception2.44052265
15MP0002736_abnormal_nociception_after2.40513827
16MP0001501_abnormal_sleep_pattern2.28609863
17MP0001440_abnormal_grooming_behavior2.26862014
18MP0002734_abnormal_mechanical_nocicepti2.26496863
19MP0004043_abnormal_pH_regulation2.22251913
20MP0001986_abnormal_taste_sensitivity2.20898556
21MP0005645_abnormal_hypothalamus_physiol2.06518499
22MP0005646_abnormal_pituitary_gland2.05826782
23MP0002067_abnormal_sensory_capabilities1.98163442
24MP0001188_hyperpigmentation1.97441005
25MP0005551_abnormal_eye_electrophysiolog1.97104011
26MP0003879_abnormal_hair_cell1.95863225
27MP0004142_abnormal_muscle_tone1.91812407
28MP0001970_abnormal_pain_threshold1.84466802
29MP0003787_abnormal_imprinting1.84082322
30MP0002822_catalepsy1.82236839
31MP0002184_abnormal_innervation1.82053310
32MP0000778_abnormal_nervous_system1.80800755
33MP0006276_abnormal_autonomic_nervous1.80087472
34MP0002733_abnormal_thermal_nociception1.76199561
35MP0003195_calcinosis1.74715737
36MP0002557_abnormal_social/conspecific_i1.73232009
37MP0006292_abnormal_olfactory_placode1.73098480
38MP0004147_increased_porphyrin_level1.69825099
39MP0001502_abnormal_circadian_rhythm1.68329264
40MP0008875_abnormal_xenobiotic_pharmacok1.62564189
41MP0001905_abnormal_dopamine_level1.57148214
42MP0008569_lethality_at_weaning1.54016314
43MP0005171_absent_coat_pigmentation1.53986795
44MP0003136_yellow_coat_color1.50664474
45MP0003122_maternal_imprinting1.47172073
46MP0004924_abnormal_behavior1.45343415
47MP0005386_behavior/neurological_phenoty1.45343415
48MP0002882_abnormal_neuron_morphology1.42423679
49MP0001984_abnormal_olfaction1.40609055
50MP0004858_abnormal_nervous_system1.38562837
51MP0004811_abnormal_neuron_physiology1.34861332
52MP0000955_abnormal_spinal_cord1.30623005
53MP0001529_abnormal_vocalization1.30061534
54MP0002638_abnormal_pupillary_reflex1.25864992
55MP0004885_abnormal_endolymph1.25026219
56MP0000538_abnormal_urinary_bladder1.24592229
57MP0002066_abnormal_motor_capabilities/c1.24023189
58MP0002163_abnormal_gland_morphology1.23464735
59MP0010386_abnormal_urinary_bladder1.21525361
60MP0002102_abnormal_ear_morphology1.21246100
61MP0001177_atelectasis1.15832175
62MP0005085_abnormal_gallbladder_physiolo1.11234125
63MP0009780_abnormal_chondrocyte_physiolo1.10514761
64MP0002876_abnormal_thyroid_physiology1.10054357
65MP0003878_abnormal_ear_physiology1.09845981
66MP0005377_hearing/vestibular/ear_phenot1.09845981
67MP0006072_abnormal_retinal_apoptosis1.09569028
68MP0004742_abnormal_vestibular_system1.08698842
69MP0005365_abnormal_bile_salt1.05187670
70MP0001485_abnormal_pinna_reflex1.04781240
71MP0003633_abnormal_nervous_system1.03475726
72MP0001765_abnormal_ion_homeostasis1.03369558
73MP0002752_abnormal_somatic_nervous1.02571136
74MP0003698_abnormal_male_reproductive1.02501514
75MP0005253_abnormal_eye_physiology1.01857406
76MP0001963_abnormal_hearing_physiology1.01326465
77MP0008004_abnormal_stomach_pH1.00532674
78MP0005379_endocrine/exocrine_gland_phen0.99941419
79MP0002229_neurodegeneration0.98751121
80MP0001919_abnormal_reproductive_system0.97713537
81MP0005360_urolithiasis0.97083818
82MP0005332_abnormal_amino_acid0.96322600
83MP0000427_abnormal_hair_cycle0.95981263
84MP0002160_abnormal_reproductive_system0.95701116
85MP0002152_abnormal_brain_morphology0.94688891
86MP0005410_abnormal_fertilization0.94544481
87MP0000230_abnormal_systemic_arterial0.93078476
88MP0003631_nervous_system_phenotype0.92619374
89MP0008872_abnormal_physiological_respon0.90353259
90MP0002928_abnormal_bile_duct0.88917183
91MP0002090_abnormal_vision0.87948491
92MP0003137_abnormal_impulse_conducting0.87791307
93MP0003119_abnormal_digestive_system0.87628227
94MP0002837_dystrophic_cardiac_calcinosis0.86067158
95MP0000026_abnormal_inner_ear0.85803387
96MP0002069_abnormal_eating/drinking_beha0.85672340
97MP0002234_abnormal_pharynx_morphology0.85585411
98MP0001756_abnormal_urination0.85035910
99MP0005394_taste/olfaction_phenotype0.84934991
100MP0005499_abnormal_olfactory_system0.84934991
101MP0000631_abnormal_neuroendocrine_gland0.83665125
102MP0003329_amyloid_beta_deposits0.82691244
103MP0002909_abnormal_adrenal_gland0.80528997
104MP0005389_reproductive_system_phenotype0.80305882
105MP0005448_abnormal_energy_balance0.79958564
106MP0001664_abnormal_digestion0.79619061
107MP0002751_abnormal_autonomic_nervous0.77452530
108MP0002693_abnormal_pancreas_physiology0.76664600
109MP0001944_abnormal_pancreas_morphology0.76576074
110MP0005174_abnormal_tail_pigmentation0.76274594
111MP0002653_abnormal_ependyma_morphology0.74905732
112MP0000751_myopathy0.72177148
113MP0008877_abnormal_DNA_methylation0.70101422
114MP0008874_decreased_physiological_sensi0.70087104
115MP0000566_synostosis0.68123408
116MP0005195_abnormal_posterior_eye0.67885633
117MP0004145_abnormal_muscle_electrophysio0.67848578
118MP0000678_abnormal_parathyroid_gland0.67317868
119MP0003632_abnormal_nervous_system0.66675105
120MP0000569_abnormal_digit_pigmentation0.66272454
121MP0003690_abnormal_glial_cell0.66019397
122MP0008961_abnormal_basal_metabolism0.65906352
123MP0003283_abnormal_digestive_organ0.64638139
124MP0003938_abnormal_ear_development0.62911992
125MP0004085_abnormal_heartbeat0.61859920
126MP0004133_heterotaxia0.61003053
127MP0005535_abnormal_body_temperature0.60898964
128MP0003011_delayed_dark_adaptation0.60843762
129MP0005409_darkened_coat_color0.59496375
130MP0003121_genomic_imprinting0.59418165
131MP0003075_altered_response_to0.58628788

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.71869771
2Myokymia (HP:0002411)5.32014240
3Febrile seizures (HP:0002373)5.04853731
4Progressive cerebellar ataxia (HP:0002073)4.76107457
5Focal seizures (HP:0007359)4.73842634
6Epileptic encephalopathy (HP:0200134)4.70830016
7Visual hallucinations (HP:0002367)4.04159133
8Atonic seizures (HP:0010819)3.62306702
9Decreased circulating renin level (HP:0003351)3.62235008
10Dynein arm defect of respiratory motile cilia (HP:0012255)3.58069443
11Absent/shortened dynein arms (HP:0200106)3.58069443
12Pancreatic cysts (HP:0001737)3.57635259
13Generalized tonic-clonic seizures (HP:0002069)3.51740199
14Attenuation of retinal blood vessels (HP:0007843)3.43091565
15Increased circulating renin level (HP:0000848)3.39024399
16Molar tooth sign on MRI (HP:0002419)3.38367032
17Abnormality of midbrain morphology (HP:0002418)3.38367032
18Gaze-evoked nystagmus (HP:0000640)3.35045221
19True hermaphroditism (HP:0010459)3.33661391
20Genetic anticipation (HP:0003743)3.29040033
21Pancreatic fibrosis (HP:0100732)3.25269924
22Dialeptic seizures (HP:0011146)3.13310294
23Absence seizures (HP:0002121)3.13031801
24Nephronophthisis (HP:0000090)3.12184201
25Congenital stationary night blindness (HP:0007642)3.04870495
26Decreased central vision (HP:0007663)2.92509248
27Broad-based gait (HP:0002136)2.87957962
28Severe visual impairment (HP:0001141)2.87321842
29Absent speech (HP:0001344)2.82755432
30Type II lissencephaly (HP:0007260)2.81026354
31Hyperactive renin-angiotensin system (HP:0000841)2.79622540
32Septo-optic dysplasia (HP:0100842)2.76181857
33Dyschromatopsia (HP:0007641)2.74577124
34Pendular nystagmus (HP:0012043)2.70497896
35Supranuclear gaze palsy (HP:0000605)2.67415545
36Dysmetria (HP:0001310)2.63008618
37Tubular atrophy (HP:0000092)2.60759045
38Limb dystonia (HP:0002451)2.60737161
39Abnormal ciliary motility (HP:0012262)2.58667887
40Dysdiadochokinesis (HP:0002075)2.58434115
41Abnormality of the renal medulla (HP:0100957)2.56795611
42Fetal akinesia sequence (HP:0001989)2.55902268
43Abnormal respiratory motile cilium morphology (HP:0005938)2.55115810
44Abnormal respiratory epithelium morphology (HP:0012253)2.55115810
45Ankle clonus (HP:0011448)2.53617053
46Metabolic alkalosis (HP:0200114)2.52265361
47Cystic liver disease (HP:0006706)2.47204241
48Abnormal drinking behavior (HP:0030082)2.45492634
49Polydipsia (HP:0001959)2.45492634
50Large for gestational age (HP:0001520)2.43923019
51Hyperventilation (HP:0002883)2.42955110
52Optic nerve hypoplasia (HP:0000609)2.42407232
53Impaired vibration sensation in the lower limbs (HP:0002166)2.42355740
54Poor eye contact (HP:0000817)2.41865333
55Amblyopia (HP:0000646)2.41817695
56Choroideremia (HP:0001139)2.41757250
57Hemiparesis (HP:0001269)2.40166094
58Epileptiform EEG discharges (HP:0011182)2.38895306
59Postural instability (HP:0002172)2.38271851
60Action tremor (HP:0002345)2.37956101
61Hyperaldosteronism (HP:0000859)2.37558228
62Impaired smooth pursuit (HP:0007772)2.37450097
63Abnormality of the renal cortex (HP:0011035)2.34616276
64Abnormal eating behavior (HP:0100738)2.31658100
65Lissencephaly (HP:0001339)2.31296256
66Abnormal respiratory motile cilium physiology (HP:0012261)2.31073316
67Abnormality of macular pigmentation (HP:0008002)2.30935921
68Urinary bladder sphincter dysfunction (HP:0002839)2.29593314
69Protruding tongue (HP:0010808)2.27808315
70Scanning speech (HP:0002168)2.27251431
71Lower limb amyotrophy (HP:0007210)2.24235501
72Blue irides (HP:0000635)2.23907143
73Anxiety (HP:0000739)2.20046208
74Abnormality of renin-angiotensin system (HP:0000847)2.19824935
75Congenital sensorineural hearing impairment (HP:0008527)2.19607178
76Hypothermia (HP:0002045)2.19270605
77Absent rod-and cone-mediated responses on ERG (HP:0007688)2.18839820
78Retinal dysplasia (HP:0007973)2.17284354
79Gait imbalance (HP:0002141)2.14458095
80Sclerocornea (HP:0000647)2.11489656
81Diplopia (HP:0000651)2.10254926
82Abnormality of binocular vision (HP:0011514)2.10254926
83Excessive salivation (HP:0003781)2.10089582
84Drooling (HP:0002307)2.10089582
85Rib fusion (HP:0000902)2.08017225
86Truncal ataxia (HP:0002078)2.07154925
87Akinesia (HP:0002304)2.06992774
88Chorioretinal atrophy (HP:0000533)2.05157053
89Ketoacidosis (HP:0001993)2.03890907
90Pachygyria (HP:0001302)2.03734831
91Hyperkalemia (HP:0002153)2.03066905
92Depression (HP:0000716)2.02611997
93Concave nail (HP:0001598)2.01069347
94Patellar aplasia (HP:0006443)2.00370585
95Abnormal social behavior (HP:0012433)1.99636930
96Impaired social interactions (HP:0000735)1.99636930
97Abnormal rod and cone electroretinograms (HP:0008323)1.97440315
98Polyuria (HP:0000103)1.97369300
99Abnormality of ocular smooth pursuit (HP:0000617)1.96617979
100Hypoalbuminemia (HP:0003073)1.95686194
101Abnormal albumin level (HP:0012116)1.95686194
102Progressive inability to walk (HP:0002505)1.95545036
103Anencephaly (HP:0002323)1.93433691
104Ketosis (HP:0001946)1.92966398
105Spastic gait (HP:0002064)1.92515643
106Incomplete penetrance (HP:0003829)1.91201907
107Abolished electroretinogram (ERG) (HP:0000550)1.90765617
108Torticollis (HP:0000473)1.90126900
109Medial flaring of the eyebrow (HP:0010747)1.89871331
110EEG with generalized epileptiform discharges (HP:0011198)1.89783347
111Hemiplegia (HP:0002301)1.89602174
112Mutism (HP:0002300)1.89252862
113Abnormality of calcium-phosphate metabolism (HP:0100530)1.89221102
114Polyphagia (HP:0002591)1.88230372
115Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.86790517
116Aplasia/Hypoplasia of the patella (HP:0006498)1.85897663
117Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.85846821
118Rhinitis (HP:0012384)1.85410240
119Oligodactyly (hands) (HP:0001180)1.85311820
120Alkalosis (HP:0001948)1.85212406
121Status epilepticus (HP:0002133)1.84865579
122Agitation (HP:0000713)1.84110163
123Decreased electroretinogram (ERG) amplitude (HP:0000654)1.83778204
124Male pseudohermaphroditism (HP:0000037)1.83694781
125Congenital primary aphakia (HP:0007707)1.82916579
126Abnormality of vitamin B metabolism (HP:0004340)1.82325067
127Hyperglycinuria (HP:0003108)1.82321847
128Central scotoma (HP:0000603)1.82269894
129Stereotypic behavior (HP:0000733)1.81858310
130Ventricular fibrillation (HP:0001663)1.81555211
131Nephrogenic diabetes insipidus (HP:0009806)1.80389295
132Chronic hepatic failure (HP:0100626)1.80267360
133Anosmia (HP:0000458)1.79829642
134Abnormality of proline metabolism (HP:0010907)1.79598078
135Hydroxyprolinuria (HP:0003080)1.79598078
136Inability to walk (HP:0002540)1.79353038
137Increased corneal curvature (HP:0100692)1.78783526
138Keratoconus (HP:0000563)1.78783526
139Lower limb muscle weakness (HP:0007340)1.77850541
140Hypsarrhythmia (HP:0002521)1.77298274
141Amelogenesis imperfecta (HP:0000705)1.77093173
142Hyperphosphatemia (HP:0002905)1.76727321
143Clumsiness (HP:0002312)1.76675816
144Bradykinesia (HP:0002067)1.75371333
145Cerebellar dysplasia (HP:0007033)1.75260828
146Bony spicule pigmentary retinopathy (HP:0007737)1.74998739
147Abnormality of glutamine family amino acid metabolism (HP:0010902)1.74557321
148Abnormal urine output (HP:0012590)1.74441698
149Severe muscular hypotonia (HP:0006829)1.74117915
150Hypokalemia (HP:0002900)1.73511857
151Furrowed tongue (HP:0000221)1.72527129
152Optic disc pallor (HP:0000543)1.69961207
153Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.69582084

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK35.12144849
2EPHA44.88168200
3CASK4.62589076
4FRK4.10150027
5MAP2K73.20503904
6TNIK2.82740983
7MARK12.67666293
8MAP4K22.64200642
9TLK12.60047656
10MAP3K42.53446923
11WNK42.53050164
12WNK32.49192665
13MAP3K92.31696585
14ACVR1B2.25083318
15PRPF4B2.20523008
16BMPR1B2.18242005
17NTRK22.12323769
18PLK22.10685448
19MAPK132.03158725
20SIK21.95464270
21MINK11.87561163
22MARK21.76837637
23STK391.73842004
24DAPK21.71501188
25SIK31.69633624
26MAP2K61.69039452
27PAK31.63574017
28MAP3K121.52454923
29STK381.49364098
30PIK3CA1.45852316
31DYRK21.42064742
32CSNK1G21.41348017
33MAPK151.40482839
34MAP2K41.37993331
35PAK61.34310669
36PRKD31.29145308
37CDK51.28282514
38PRKCG1.25187461
39CAMK11.22202263
40FES1.21487206
41CAMKK21.19479221
42CAMK2A1.18452571
43NUAK11.16054756
44SGK21.14089852
45CAMK2B1.13867857
46SGK2231.11061746
47SGK4941.11061746
48GRK51.10478425
49AKT31.06635442
50PINK11.06318068
51DAPK11.05868685
52CAMKK11.04171581
53RIPK41.03680173
54TNK21.02368983
55ADRBK10.94889510
56NEK60.90736045
57MAP3K130.88908669
58BMPR20.85427567
59KSR10.85294060
60DYRK1A0.83760104
61SGK10.83306716
62PRKCE0.83282748
63CDK190.83087196
64PRKCI0.80641697
65UHMK10.79767677
66MKNK20.79759714
67NTRK10.77276223
68CSNK1G30.75556635
69BRAF0.75094034
70ADRBK20.73834259
71GRK10.73270211
72CDC42BPA0.73118300
73STK38L0.71128921
74BCR0.68764102
75CSNK1G10.68381547
76INSRR0.67666710
77PRKAA10.67254824
78NME10.66528065
79FER0.66030296
80ZAK0.65468731
81STK110.65301091
82SGK30.65138251
83PHKG10.64091515
84PHKG20.64091515
85LMTK20.63546393
86CDK180.62445870
87CDK150.60701952
88FGFR20.60098878
89LATS20.60010234
90MAP2K20.59970906
91PKN10.59520058
92PNCK0.58567205
93TAOK20.56438577
94PRKCH0.55975936
95CSNK1A1L0.55590379
96OXSR10.54965581
97TRIM280.54492081
98MAPKAPK30.51621265
99CAMK2G0.51611218
100CDK11A0.51522013
101CAMK2D0.51504981
102CDK30.50432837
103MST1R0.47958026
104CDK140.47034818
105CAMK40.46742497
106MAP3K70.45864218
107CAMK1D0.44499639
108MAP3K60.43092002
109MAPKAPK50.42659106
110ERBB20.42336592
111MUSK0.42064447
112TXK0.41665578
113EPHA30.40383577
114GRK70.40199238
115PRKG10.39359595
116CSNK1D0.39201659
117PRKAA20.38808392
118RPS6KA30.38799577
119BMX0.38528873
120ARAF0.37912176
121PRKCZ0.37703133
122WNK10.37691267
123PRKCA0.37092040
124CAMK1G0.36034137
125BCKDK0.35965677
126PDK10.35899026
127ALK0.35255459
128PRKD20.34940981
129TAF10.34446183
130PTK2B0.34243553
131CCNB10.34063260
132PRKACA0.34000072
133TYRO30.33916133
134PRKG20.33881187
135PRKCB0.32737747
136PRKCQ0.31406145
137KSR20.31250658
138RPS6KB10.30730102
139MAPK100.29229108
140CSNK1A10.29117681
141EIF2AK20.28652500
142MAP3K20.28517451

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.66523013
2Synaptic vesicle cycle_Homo sapiens_hsa047213.59466781
3Circadian entrainment_Homo sapiens_hsa047133.09071840
4Morphine addiction_Homo sapiens_hsa050322.95624209
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.95263004
6GABAergic synapse_Homo sapiens_hsa047272.88308832
7Glutamatergic synapse_Homo sapiens_hsa047242.81408689
8Olfactory transduction_Homo sapiens_hsa047402.60585686
9Amphetamine addiction_Homo sapiens_hsa050312.47635184
10Nitrogen metabolism_Homo sapiens_hsa009102.45514045
11Phototransduction_Homo sapiens_hsa047442.43208438
12Linoleic acid metabolism_Homo sapiens_hsa005912.35816974
13alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.35631750
14Long-term potentiation_Homo sapiens_hsa047202.25612706
15Maturity onset diabetes of the young_Homo sapiens_hsa049502.19612571
16Salivary secretion_Homo sapiens_hsa049702.16389190
17Taste transduction_Homo sapiens_hsa047422.06082353
18Insulin secretion_Homo sapiens_hsa049112.05178599
19Dopaminergic synapse_Homo sapiens_hsa047282.02331806
20Caffeine metabolism_Homo sapiens_hsa002321.94300513
21Butanoate metabolism_Homo sapiens_hsa006501.93334224
22Cyanoamino acid metabolism_Homo sapiens_hsa004601.92694059
23Serotonergic synapse_Homo sapiens_hsa047261.92256978
24Calcium signaling pathway_Homo sapiens_hsa040201.90937643
25Cholinergic synapse_Homo sapiens_hsa047251.88482069
26Cocaine addiction_Homo sapiens_hsa050301.86731551
27Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.83872814
28Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.82733669
29Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.80945474
30Aldosterone synthesis and secretion_Homo sapiens_hsa049251.70730168
31Tryptophan metabolism_Homo sapiens_hsa003801.67166625
32Gastric acid secretion_Homo sapiens_hsa049711.63692601
33Long-term depression_Homo sapiens_hsa047301.56285755
34Oxytocin signaling pathway_Homo sapiens_hsa049211.51590755
35Renin secretion_Homo sapiens_hsa049241.48329433
36Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.47721342
37Selenocompound metabolism_Homo sapiens_hsa004501.46999138
38cAMP signaling pathway_Homo sapiens_hsa040241.43910702
39Fat digestion and absorption_Homo sapiens_hsa049751.40746012
40Collecting duct acid secretion_Homo sapiens_hsa049661.40274463
41Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.33823885
42Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.33468449
43Sulfur relay system_Homo sapiens_hsa041221.32192324
44Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.31652503
45Axon guidance_Homo sapiens_hsa043601.30163844
46Histidine metabolism_Homo sapiens_hsa003401.30103737
47Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.29558600
48Oxidative phosphorylation_Homo sapiens_hsa001901.25299507
49Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.23435742
50Sulfur metabolism_Homo sapiens_hsa009201.18994228
51Type II diabetes mellitus_Homo sapiens_hsa049301.17219419
52Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.17059983
53Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.15589883
54Phosphatidylinositol signaling system_Homo sapiens_hsa040701.14598443
55GnRH signaling pathway_Homo sapiens_hsa049121.13608685
56Steroid hormone biosynthesis_Homo sapiens_hsa001401.08406793
57Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.07876637
58Gap junction_Homo sapiens_hsa045401.00437580
59ABC transporters_Homo sapiens_hsa020101.00065594
60Vascular smooth muscle contraction_Homo sapiens_hsa042700.98805853
61Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.98437182
62Chemical carcinogenesis_Homo sapiens_hsa052040.98290357
63Retinol metabolism_Homo sapiens_hsa008300.95791951
64Vitamin digestion and absorption_Homo sapiens_hsa049770.95507276
65cGMP-PKG signaling pathway_Homo sapiens_hsa040220.94271424
66Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.92741060
67Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.90527708
68Circadian rhythm_Homo sapiens_hsa047100.89483641
69Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.88517909
70Glycerolipid metabolism_Homo sapiens_hsa005610.88080368
71ErbB signaling pathway_Homo sapiens_hsa040120.86712303
72Parkinsons disease_Homo sapiens_hsa050120.85701020
73Vibrio cholerae infection_Homo sapiens_hsa051100.85135629
74Ovarian steroidogenesis_Homo sapiens_hsa049130.84368042
75Melanogenesis_Homo sapiens_hsa049160.79945384
76Cardiac muscle contraction_Homo sapiens_hsa042600.79696336
77Estrogen signaling pathway_Homo sapiens_hsa049150.78707750
78Dilated cardiomyopathy_Homo sapiens_hsa054140.78114551
79SNARE interactions in vesicular transport_Homo sapiens_hsa041300.78053140
80Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.76581913
81Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.76405207
82Arginine and proline metabolism_Homo sapiens_hsa003300.74250924
83Phospholipase D signaling pathway_Homo sapiens_hsa040720.74110064
84Inositol phosphate metabolism_Homo sapiens_hsa005620.74025837
85Arachidonic acid metabolism_Homo sapiens_hsa005900.74011496
86Pancreatic secretion_Homo sapiens_hsa049720.73957047
87Pentose and glucuronate interconversions_Homo sapiens_hsa000400.73483444
88beta-Alanine metabolism_Homo sapiens_hsa004100.72260889
89Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.71735097
90Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.70762143
91Fatty acid biosynthesis_Homo sapiens_hsa000610.70135249
92MAPK signaling pathway_Homo sapiens_hsa040100.69403575
93Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.69249292
94Ras signaling pathway_Homo sapiens_hsa040140.67340097
95Basal transcription factors_Homo sapiens_hsa030220.66880952
96Peroxisome_Homo sapiens_hsa041460.66740962
97Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.66116804
98Propanoate metabolism_Homo sapiens_hsa006400.65024709
99Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.64922709
100Glioma_Homo sapiens_hsa052140.64428475
101Type I diabetes mellitus_Homo sapiens_hsa049400.62103412
102Choline metabolism in cancer_Homo sapiens_hsa052310.61643190
103Alzheimers disease_Homo sapiens_hsa050100.61519420
104Fatty acid degradation_Homo sapiens_hsa000710.60771705
105Primary bile acid biosynthesis_Homo sapiens_hsa001200.60639532
106Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58993383
107Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.58981490
108Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.54797791
109Wnt signaling pathway_Homo sapiens_hsa043100.54243911
110Rap1 signaling pathway_Homo sapiens_hsa040150.51052720
111Thyroid hormone synthesis_Homo sapiens_hsa049180.50581645
112Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.49711832
113Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.49433840
114Arginine biosynthesis_Homo sapiens_hsa002200.49425783
115Oocyte meiosis_Homo sapiens_hsa041140.49339552
116Huntingtons disease_Homo sapiens_hsa050160.47003884
117Rheumatoid arthritis_Homo sapiens_hsa053230.45157782
118Metabolic pathways_Homo sapiens_hsa011000.44868842
119Dorso-ventral axis formation_Homo sapiens_hsa043200.44320287
120Alcoholism_Homo sapiens_hsa050340.42909573
121African trypanosomiasis_Homo sapiens_hsa051430.41900594
122Mineral absorption_Homo sapiens_hsa049780.41672119
123Carbohydrate digestion and absorption_Homo sapiens_hsa049730.39741803
124Fanconi anemia pathway_Homo sapiens_hsa034600.39447537
125Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.38122623
126Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.38087207
127Fatty acid metabolism_Homo sapiens_hsa012120.37034678
128Regulation of actin cytoskeleton_Homo sapiens_hsa048100.29742921
129Chemokine signaling pathway_Homo sapiens_hsa040620.29716131
130Folate biosynthesis_Homo sapiens_hsa007900.27943684
131Glycerophospholipid metabolism_Homo sapiens_hsa005640.27268855
132Neurotrophin signaling pathway_Homo sapiens_hsa047220.25895437
133Glucagon signaling pathway_Homo sapiens_hsa049220.23538174
134Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.23524416
135Bile secretion_Homo sapiens_hsa049760.23326577
136Endocytosis_Homo sapiens_hsa041440.22979255
137Sphingolipid signaling pathway_Homo sapiens_hsa040710.21619988
138Sphingolipid metabolism_Homo sapiens_hsa006000.20462005
139Melanoma_Homo sapiens_hsa052180.19954067
140Hedgehog signaling pathway_Homo sapiens_hsa043400.19261124
141Thyroid hormone signaling pathway_Homo sapiens_hsa049190.19063104
142Ether lipid metabolism_Homo sapiens_hsa005650.15196995
143Phagosome_Homo sapiens_hsa041450.14353254
144Autoimmune thyroid disease_Homo sapiens_hsa053200.12627591
145Regulation of autophagy_Homo sapiens_hsa041400.10243127
146Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.09476568
147Longevity regulating pathway - mammal_Homo sapiens_hsa042110.08825188

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »