EML3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.13223190
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.13223190
3antigen processing and presentation of endogenous antigen (GO:0019883)5.55357398
4positive regulation of gamma-delta T cell activation (GO:0046645)5.24345025
5regulation of gamma-delta T cell differentiation (GO:0045586)4.39557794
6regulation of gamma-delta T cell activation (GO:0046643)4.06777586
7modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.88574134
8positive regulation by organism of defense response of other organism involved in symbiotic interact3.88574134
9modulation by symbiont of host immune response (GO:0052553)3.88574134
10positive regulation by symbiont of host defense response (GO:0052509)3.88574134
11modulation by symbiont of host defense response (GO:0052031)3.88574134
12modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.88574134
13ribosomal small subunit assembly (GO:0000028)3.72310982
14response to peptidoglycan (GO:0032494)3.71366549
15detection of bacterium (GO:0016045)3.68979840
16detection of other organism (GO:0098543)3.66179900
17positive thymic T cell selection (GO:0045059)3.59232794
18antigen processing and presentation via MHC class Ib (GO:0002475)3.58472300
19negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.56918438
20negative regulation of erythrocyte differentiation (GO:0045647)3.49687890
21germinal center formation (GO:0002467)3.46056145
22positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.43068455
23positive regulation of histone deacetylation (GO:0031065)3.33453045
24macrophage activation involved in immune response (GO:0002281)3.32368673
25negative thymic T cell selection (GO:0045060)3.26205338
26leukocyte aggregation (GO:0070486)3.26044828
27positive regulation of B cell differentiation (GO:0045579)3.24515449
28regulation of B cell differentiation (GO:0045577)3.20965056
29neutrophil activation involved in immune response (GO:0002283)3.18242126
30negative T cell selection (GO:0043383)3.16349847
31Arp2/3 complex-mediated actin nucleation (GO:0034314)3.14457641
32positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.12810973
33negative regulation of phagocytosis (GO:0050765)3.12022906
34viral transcription (GO:0019083)3.10739362
35thymic T cell selection (GO:0045061)3.10200304
36regulation of B cell receptor signaling pathway (GO:0050855)3.09663740
37regulation of interleukin-12 biosynthetic process (GO:0045075)3.07397221
38pentose-phosphate shunt (GO:0006098)3.02245626
39detection of external biotic stimulus (GO:0098581)3.01060319
40antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.99719732
41translational termination (GO:0006415)2.91726500
42negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.89227423
43negative regulation of cell killing (GO:0031342)2.89227423
44negative regulation of lymphocyte mediated immunity (GO:0002707)2.87131915
45regulation of dendritic cell antigen processing and presentation (GO:0002604)2.85774616
46B cell receptor signaling pathway (GO:0050853)2.85637294
47negative regulation of leukocyte mediated immunity (GO:0002704)2.85520589
48JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.81869694
49natural killer cell differentiation (GO:0001779)2.81207242
50regulation of leukocyte degranulation (GO:0043300)2.79208006
51regulation of T cell tolerance induction (GO:0002664)2.78363753
52positive regulation of natural killer cell differentiation (GO:0032825)2.77497092
53NIK/NF-kappaB signaling (GO:0038061)2.75878086
54lipopolysaccharide-mediated signaling pathway (GO:0031663)2.75838921
55definitive hemopoiesis (GO:0060216)2.74447471
56regulation of mast cell degranulation (GO:0043304)2.72566082
57mannose metabolic process (GO:0006013)2.71927590
58regulation of type I interferon-mediated signaling pathway (GO:0060338)2.71578778
59negative regulation of T cell mediated immunity (GO:0002710)2.71413117
60regulation of myeloid leukocyte mediated immunity (GO:0002886)2.70020553
61positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.67736822
62positive regulation of protein deacetylation (GO:0090312)2.66760612
63translational elongation (GO:0006414)2.64700233
64detection of biotic stimulus (GO:0009595)2.64229610
65valine metabolic process (GO:0006573)2.64189248
66regulation of T-helper 2 cell differentiation (GO:0045628)2.63461531
67defense response to protozoan (GO:0042832)2.63212656
68T cell migration (GO:0072678)2.61973170
69megakaryocyte development (GO:0035855)2.60854068
70T cell apoptotic process (GO:0070231)2.60033636
71negative regulation of interleukin-12 production (GO:0032695)2.60020404
72regulation of tolerance induction (GO:0002643)2.57477510
73T cell selection (GO:0045058)2.56844489
74regulation of interleukin-2 biosynthetic process (GO:0045076)2.56440895
75modulation by symbiont of host cellular process (GO:0044068)2.56020338
76response to host (GO:0075136)2.55462087
77response to host defenses (GO:0052200)2.55462087
78response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.55462087
79regulation of extracellular matrix disassembly (GO:0010715)2.54786261
80response to protozoan (GO:0001562)2.54626748
81NADPH regeneration (GO:0006740)2.54604066
82morphogenesis of an endothelium (GO:0003159)2.53757821
83endothelial tube morphogenesis (GO:0061154)2.53757821
84positive regulation of Cdc42 GTPase activity (GO:0043089)2.53208467
85myeloid dendritic cell differentiation (GO:0043011)2.53206393
86negative regulation of cytokine production involved in immune response (GO:0002719)2.52910745
873-UTR-mediated mRNA stabilization (GO:0070935)2.51178311
88response to host immune response (GO:0052572)2.50363059
89response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.50363059
90regulation of natural killer cell differentiation (GO:0032823)2.49612660
91cellular extravasation (GO:0045123)2.49462652
92detection of molecule of bacterial origin (GO:0032490)2.49428532
93modulation by virus of host process (GO:0019054)2.46757597
94regulation of necroptotic process (GO:0060544)2.46485496
95response to muramyl dipeptide (GO:0032495)2.46382326
96negative regulation of interleukin-6 production (GO:0032715)2.45762229
97SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.45706658
98response to type I interferon (GO:0034340)2.45625130
99T cell homeostasis (GO:0043029)2.45285907
100negative regulation of granulocyte differentiation (GO:0030853)2.45092574
101regulation of natural killer cell mediated immunity (GO:0002715)2.44602995
102regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.44602995
103regulation of erythrocyte differentiation (GO:0045646)2.44342481
104response to laminar fluid shear stress (GO:0034616)2.44093724
105positive regulation of Rap GTPase activity (GO:0032854)2.43966417
106DNA unwinding involved in DNA replication (GO:0006268)2.43480817
107interferon-gamma-mediated signaling pathway (GO:0060333)2.43179510
108regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.42284301
109nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.42182406
110cellular response to zinc ion (GO:0071294)2.41233941
111pinocytosis (GO:0006907)2.40949946
112negative regulation of type 2 immune response (GO:0002829)2.40498373
113myeloid cell activation involved in immune response (GO:0002275)2.40380657
114regulation of antigen processing and presentation (GO:0002577)2.39462339
115cellular response to type I interferon (GO:0071357)2.38071753
116type I interferon signaling pathway (GO:0060337)2.38071753
117protein targeting to ER (GO:0045047)2.37551382
118positive T cell selection (GO:0043368)2.37486550
119regulation of response to interferon-gamma (GO:0060330)2.37069182
120leukocyte cell-cell adhesion (GO:0007159)2.36816711
121cotranslational protein targeting to membrane (GO:0006613)2.33134461
122lymphocyte homeostasis (GO:0002260)2.32697355
123negative regulation of stress fiber assembly (GO:0051497)2.31744196
124embryonic hemopoiesis (GO:0035162)2.30189243
125B cell mediated immunity (GO:0019724)2.29941952
126regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.29068873
127lymphocyte apoptotic process (GO:0070227)2.28602038
128viral life cycle (GO:0019058)2.28516144
129regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.26966351
130actin nucleation (GO:0045010)2.26503848
131establishment of protein localization to endoplasmic reticulum (GO:0072599)2.25515599
132folic acid-containing compound biosynthetic process (GO:0009396)2.24938369
133negative regulation of innate immune response (GO:0045824)2.20773517
134response to interleukin-15 (GO:0070672)2.20495014
135interferon-gamma production (GO:0032609)2.19310355
136tolerance induction (GO:0002507)2.18605547
137protein localization to endoplasmic reticulum (GO:0070972)2.18514695
138regulation of interferon-beta biosynthetic process (GO:0045357)2.18435289
139immunoglobulin mediated immune response (GO:0016064)2.18237073
140maternal placenta development (GO:0001893)2.17281341
141positive regulation of lamellipodium assembly (GO:0010592)2.16760676
142negative regulation of RNA splicing (GO:0033119)2.16428426
143Golgi transport vesicle coating (GO:0048200)2.16211773
144COPI coating of Golgi vesicle (GO:0048205)2.16211773
145hepatocyte apoptotic process (GO:0097284)2.14030608
146adaptation of signaling pathway (GO:0023058)2.13548555
147mucosal-associated lymphoid tissue development (GO:0048537)2.12856429
148Peyers patch development (GO:0048541)2.12856429
149positive regulation of isotype switching (GO:0045830)2.12461632
150leukocyte homeostasis (GO:0001776)2.12235913
151defense response to fungus (GO:0050832)2.10713834

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.13196554
2MYC_22102868_ChIP-Seq_BL_Human3.30216416
3IRF8_22096565_ChIP-ChIP_GC-B_Human3.19273657
4EGR1_19374776_ChIP-ChIP_THP-1_Human2.90482228
5VDR_21846776_ChIP-Seq_THP-1_Human2.83134852
6FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.74102041
7STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.73826514
8NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.60501135
9MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.56345062
10SCL_19346495_ChIP-Seq_HPC-7_Human2.41996320
11EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.36974670
12* MAF_26560356_Chip-Seq_TH1_Human2.12133786
13FOXM1_23109430_ChIP-Seq_U2OS_Human2.06419920
14TP63_17297297_ChIP-ChIP_HaCaT_Human2.05361016
15TCF7_22412390_ChIP-Seq_EML_Mouse2.04525388
16MYB_21317192_ChIP-Seq_ERMYB_Mouse2.02972541
17IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.01450662
18UTX_26944678_Chip-Seq_JUKART_Human1.95565441
19RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.95526145
20SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.95082232
21SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.90149243
22BP1_19119308_ChIP-ChIP_Hs578T_Human1.88194534
23ELK3_25401928_ChIP-Seq_HUVEC_Human1.85948211
24NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.85801362
25BRD4_27068464_Chip-Seq_AML-cells_Mouse1.85102125
26VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.83862658
27MYB_26560356_Chip-Seq_TH2_Human1.82404034
28VDR_24763502_ChIP-Seq_THP-1_Human1.82144185
29NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.78815845
30MYB_26560356_Chip-Seq_TH1_Human1.78053173
31* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.76238149
32IRF8_21731497_ChIP-ChIP_J774_Mouse1.74596943
33KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.73179629
34SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.72657933
35ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.71565442
36TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.69499565
37SPI1_23547873_ChIP-Seq_NB4_Human1.67778185
38RUNX1_22412390_ChIP-Seq_EML_Mouse1.66832648
39E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.66492847
40KDM2B_26808549_Chip-Seq_DND41_Human1.65589255
41FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.64365602
42TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.63137763
43STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.62976791
44KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.62671624
45STAT4_19710469_ChIP-ChIP_TH1__Mouse1.60468686
46PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.59638565
47STAT6_21828071_ChIP-Seq_BEAS2B_Human1.55611009
48IRF8_27001747_Chip-Seq_BMDM_Mouse1.54031556
49RUNX_20019798_ChIP-Seq_JUKART_Human1.53875965
50IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.53381873
51ELF1_17652178_ChIP-ChIP_JURKAT_Human1.50535692
52FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.49733312
53PPARA_22158963_ChIP-Seq_LIVER_Mouse1.48621217
54CTCF_27219007_Chip-Seq_ERYTHROID_Human1.48051539
55CIITA_25753668_ChIP-Seq_RAJI_Human1.47235795
56KDM2B_26808549_Chip-Seq_SUP-B15_Human1.46643327
57KDM2B_26808549_Chip-Seq_K562_Human1.45478980
58* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.45374999
59* MAF_26560356_Chip-Seq_TH2_Human1.42923892
60EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.42529836
61STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.42246478
62SA1_27219007_Chip-Seq_ERYTHROID_Human1.41945330
63P68_20966046_ChIP-Seq_HELA_Human1.41609658
64GATA1_22383799_ChIP-Seq_G1ME_Mouse1.38499390
65GATA1_22025678_ChIP-Seq_K562_Human1.36683007
66TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.35828314
67LXR_22292898_ChIP-Seq_THP-1_Human1.34354942
68RXR_22158963_ChIP-Seq_LIVER_Mouse1.33642027
69* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.32035625
70SPI1_23127762_ChIP-Seq_K562_Human1.29221268
71MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.26478970
72GATA2_22383799_ChIP-Seq_G1ME_Mouse1.26399155
73RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.26075585
74* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.23005367
75ESR2_21235772_ChIP-Seq_MCF-7_Human1.22728017
76* BCOR_27268052_Chip-Seq_Bcells_Human1.22095598
77EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.22076281
78CLOCK_20551151_ChIP-Seq_293T_Human1.21677827
79SMC4_20622854_ChIP-Seq_HELA_Human1.21208907
80MYC_18555785_ChIP-Seq_MESCs_Mouse1.20295015
81BCL6_27268052_Chip-Seq_Bcells_Human1.19912677
82GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.19892242
83NCOR1_26117541_ChIP-Seq_K562_Human1.19169912
84TET1_21451524_ChIP-Seq_MESCs_Mouse1.18818038
85FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.18691000
86PU.1_20513432_ChIP-Seq_Bcells_Mouse1.17708926
87TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.17020906
88PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.15927030
89GATA1_19941826_ChIP-Seq_K562_Human1.15207777
90* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.13723512
91* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.10470317
92NOTCH1_21737748_ChIP-Seq_TLL_Human1.10217301
93* GATA1_19941827_ChIP-Seq_MEL_Mouse1.09028315
94RARG_19884340_ChIP-ChIP_MEFs_Mouse1.08742031
95* RACK7_27058665_Chip-Seq_MCF-7_Human1.07770883
96P300_27058665_Chip-Seq_ZR-75-30cells_Human1.06573084
97XRN2_22483619_ChIP-Seq_HELA_Human1.05009971
98GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.04779071
99E2F4_17652178_ChIP-ChIP_JURKAT_Human1.03686899
100RUNX1_27514584_Chip-Seq_MCF-7_Human1.03651483
101CREB1_26743006_Chip-Seq_LNCaP_Human1.03581681
102GATA3_27048872_Chip-Seq_THYMUS_Human1.02294790
103DNAJC2_21179169_ChIP-ChIP_NT2_Human1.01419414
104LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.00241838
105KDM2B_26808549_Chip-Seq_JURKAT_Human0.99939694
106ZFP281_18757296_ChIP-ChIP_E14_Mouse0.99912705
107* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.99408229
108RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.98564951
109PU_27001747_Chip-Seq_BMDM_Mouse0.98098344
110TFEB_21752829_ChIP-Seq_HELA_Human0.97875847
111CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97801239
112THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.97196233
113GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.96601405
114CTCF_26484167_Chip-Seq_Bcells_Mouse0.96069556
115CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.95766985
116CTCF_21964334_ChIP-Seq_BJAB-B_Human0.95624598
117SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.94817139
118TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.94142166
119FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.93860597
120ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.93791750
121* TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.93664901
122* ATF3_27146783_Chip-Seq_COLON_Human0.91582171
123E2F1_21310950_ChIP-Seq_MCF-7_Human0.90727654
124DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.90036629
125* ELF1_20517297_ChIP-Seq_JURKAT_Human0.89129365
126CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.88277762
127MYC_19079543_ChIP-ChIP_MESCs_Mouse0.87784828
128CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.86416913
129LXR_22158963_ChIP-Seq_LIVER_Mouse0.86322864
130* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.85846930

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000685_abnormal_immune_system2.73553894
2MP0001835_abnormal_antigen_presentation2.54927380
3MP0002396_abnormal_hematopoietic_system2.52334625
4MP0003300_gastrointestinal_ulcer2.35809932
5MP0003436_decreased_susceptibility_to2.30937268
6MP0003763_abnormal_thymus_physiology2.25524453
7MP0001800_abnormal_humoral_immune2.19902463
8MP0009278_abnormal_bone_marrow2.15361020
9MP0005387_immune_system_phenotype2.14151981
10MP0001790_abnormal_immune_system2.14151981
11MP0005451_abnormal_body_composition2.14014828
12MP0003303_peritoneal_inflammation2.08682154
13MP0003705_abnormal_hypodermis_morpholog2.04297572
14MP0008260_abnormal_autophagy1.95240610
15MP0004808_abnormal_hematopoietic_stem1.94752547
16MP0000465_gastrointestinal_hemorrhage1.93396903
17MP0002166_altered_tumor_susceptibility1.92175360
18MP0010352_gastrointestinal_tract_polyps1.90398601
19MP0002452_abnormal_antigen_presenting1.89362069
20MP0005397_hematopoietic_system_phenotyp1.85572768
21MP0001545_abnormal_hematopoietic_system1.85572768
22MP0003011_delayed_dark_adaptation1.84029512
23MP0005464_abnormal_platelet_physiology1.84011146
24MP0002398_abnormal_bone_marrow1.82739780
25MP0002420_abnormal_adaptive_immunity1.78963416
26MP0002723_abnormal_immune_serum1.77554768
27MP0001819_abnormal_immune_cell1.77420283
28MP0005000_abnormal_immune_tolerance1.77330411
29MP0005025_abnormal_response_to1.74053024
30MP0001873_stomach_inflammation1.71385017
31MP0009840_abnormal_foam_cell1.70033962
32MP0004947_skin_inflammation1.69536516
33MP0005671_abnormal_response_to1.68591860
34MP0009785_altered_susceptibility_to1.65911993
35MP0002722_abnormal_immune_system1.61785294
36MP0009333_abnormal_splenocyte_physiolog1.61500185
37MP0002419_abnormal_innate_immunity1.61364851
38MP0000689_abnormal_spleen_morphology1.59811033
39MP0000716_abnormal_immune_system1.58966761
40MP0002405_respiratory_system_inflammati1.56773271
41MP0010155_abnormal_intestine_physiology1.54412761
42MP0003828_pulmonary_edema1.53688975
43MP0003566_abnormal_cell_adhesion1.53107603
44MP0002429_abnormal_blood_cell1.45417236
45MP0005076_abnormal_cell_differentiation1.41391107
46MP0000703_abnormal_thymus_morphology1.38470915
47MP0004381_abnormal_hair_follicle1.37295759
48MP0005023_abnormal_wound_healing1.35606708
49MP0003091_abnormal_cell_migration1.35049122
50MP0003724_increased_susceptibility_to1.34395752
51MP0001845_abnormal_inflammatory_respons1.33022518
52MP0001853_heart_inflammation1.31875464
53MP0000490_abnormal_crypts_of1.27899606
54MP0006054_spinal_hemorrhage1.27004795
55MP0005666_abnormal_adipose_tissue1.24547625
56MP0000858_altered_metastatic_potential1.23139857
57MP0002006_tumorigenesis1.22707947
58MP0003191_abnormal_cellular_cholesterol1.20846211
59MP0001533_abnormal_skeleton_physiology1.18454841
60MP0002933_joint_inflammation1.18317559
61MP0003866_abnormal_defecation1.15514497
62MP0003279_aneurysm1.14414937
63MP0005058_abnormal_lysosome_morphology1.13663844
64MP0010307_abnormal_tumor_latency1.09679056
65MP0002148_abnormal_hypersensitivity_rea1.09008324
66MP0003075_altered_response_to1.08048006
67MP0006082_CNS_inflammation1.07872019
68MP0002138_abnormal_hepatobiliary_system1.07867848
69MP0008438_abnormal_cutaneous_collagen1.06268660
70MP0010368_abnormal_lymphatic_system1.05132866
71MP0005310_abnormal_salivary_gland1.04486632
72MP0008469_abnormal_protein_level1.02440321
73MP0005390_skeleton_phenotype1.01887777
74MP0002877_abnormal_melanocyte_morpholog1.00862825
75MP0002019_abnormal_tumor_incidence0.99903498
76MP0001348_abnormal_lacrimal_gland0.98845043
77MP0002060_abnormal_skin_morphology0.97818533
78MP0000609_abnormal_liver_physiology0.97807875
79MP0005375_adipose_tissue_phenotype0.94270817
80MP0004858_abnormal_nervous_system0.93880919
81MP0003690_abnormal_glial_cell0.91889317
82MP0004510_myositis0.90921586
83MP0004185_abnormal_adipocyte_glucose0.89056129
84MP0000604_amyloidosis0.88610036
85MP0001851_eye_inflammation0.87912935
86MP0001915_intracranial_hemorrhage0.87549892
87MP0003448_altered_tumor_morphology0.87347018
88MP0000249_abnormal_blood_vessel0.86687976
89MP0000598_abnormal_liver_morphology0.86612738
90MP0005166_decreased_susceptibility_to0.86185139
91MP0000343_altered_response_to0.86115223
92MP0005409_darkened_coat_color0.84306433
93MP0000767_abnormal_smooth_muscle0.82494077
94MP0003693_abnormal_embryo_hatching0.82464331
95MP0005365_abnormal_bile_salt0.80782386
96MP0003183_abnormal_peptide_metabolism0.80752112
97MP0003453_abnormal_keratinocyte_physiol0.80305498
98MP0001663_abnormal_digestive_system0.79849698
99MP0001958_emphysema0.79727885
100MP0004883_abnormal_blood_vessel0.79373917
101MP0003077_abnormal_cell_cycle0.79336906
102MP0003795_abnormal_bone_structure0.78775527
103MP0008007_abnormal_cellular_replicative0.78542884
104MP0002796_impaired_skin_barrier0.77564140
105MP0005164_abnormal_response_to0.77196721
106MP0010234_abnormal_vibrissa_follicle0.76429482
107MP0009763_increased_sensitivity_to0.76074157
108MP0001243_abnormal_dermal_layer0.75675044
109MP0005360_urolithiasis0.75332343
110MP0009764_decreased_sensitivity_to0.74936447
111MP0004130_abnormal_muscle_cell0.74601170
112MP0000678_abnormal_parathyroid_gland0.73473806
113MP0002009_preneoplasia0.72798151
114MP0009931_abnormal_skin_appearance0.72671263
115MP0001879_abnormal_lymphatic_vessel0.72667930
116MP0008961_abnormal_basal_metabolism0.72119662
117MP0003045_fibrosis0.71560287
118MP0005174_abnormal_tail_pigmentation0.70814374
119MP0003252_abnormal_bile_duct0.70664929
120MP0005220_abnormal_exocrine_pancreas0.70506711
121MP0001849_ear_inflammation0.70457693
122MP0010329_abnormal_lipoprotein_level0.70277499
123MP0002998_abnormal_bone_remodeling0.70180712
124MP0003172_abnormal_lysosome_physiology0.70065052
125MP0009115_abnormal_fat_cell0.68683563
126MP0002132_abnormal_respiratory_system0.68535841
127MP0000477_abnormal_intestine_morphology0.68388454
128MP0001216_abnormal_epidermal_layer0.67026728
129MP0003111_abnormal_nucleus_morphology0.66932750
130MP0000350_abnormal_cell_proliferation0.66887348
131MP0003943_abnormal_hepatobiliary_system0.66581421

Predicted human phenotypes

RankGene SetZ-score
1Congenital stationary night blindness (HP:0007642)3.50463254
2Absent rod-and cone-mediated responses on ERG (HP:0007688)3.25905690
3Eczematoid dermatitis (HP:0000976)3.22930330
4Elevated erythrocyte sedimentation rate (HP:0003565)3.20788964
5Chronic otitis media (HP:0000389)3.19141943
6Thrombocytosis (HP:0001894)3.14882672
7Abnormal delayed hypersensitivity skin test (HP:0002963)3.14719972
8Autoimmune thrombocytopenia (HP:0001973)3.13993934
9Spontaneous hematomas (HP:0007420)3.08036088
10IgM deficiency (HP:0002850)2.97679006
11Abnormality of the nasal mucosa (HP:0000433)2.94628921
12Recurrent viral infections (HP:0004429)2.91939558
13Gastrointestinal inflammation (HP:0004386)2.91177210
14Interstitial pulmonary disease (HP:0006530)2.88704799
15Abnormal rod and cone electroretinograms (HP:0008323)2.86631292
16Myositis (HP:0100614)2.83674603
17Inflammation of the large intestine (HP:0002037)2.83335249
18Bony spicule pigmentary retinopathy (HP:0007737)2.82530952
19Nasal polyposis (HP:0100582)2.80676317
20Pigmentary retinal degeneration (HP:0001146)2.77593999
21Cellulitis (HP:0100658)2.75989091
22Chronic obstructive pulmonary disease (HP:0006510)2.75249118
23Obstructive lung disease (HP:0006536)2.75249118
24Colitis (HP:0002583)2.73962014
25Recurrent fungal infections (HP:0002841)2.69252600
26Abnormality of the fingertips (HP:0001211)2.66044784
27Gingivitis (HP:0000230)2.63943848
28Obstructive sleep apnea (HP:0002870)2.63323609
29Gastrointestinal infarctions (HP:0005244)2.61867276
30Pustule (HP:0200039)2.61825685
31Recurrent bronchitis (HP:0002837)2.61625260
32Recurrent abscess formation (HP:0002722)2.61147559
33Impaired platelet aggregation (HP:0003540)2.59609609
34Abnormal platelet function (HP:0011869)2.59609609
35Cerebral aneurysm (HP:0004944)2.53993214
36Prolonged bleeding time (HP:0003010)2.52965711
37Petechiae (HP:0000967)2.46903471
38Recurrent bacterial skin infections (HP:0005406)2.42473489
39T lymphocytopenia (HP:0005403)2.40840859
40Broad face (HP:0000283)2.40707219
41Abnormality of T cell number (HP:0011839)2.39555425
42Abnormality of T cells (HP:0002843)2.39348112
43Protrusio acetabuli (HP:0003179)2.38632837
44Gastrointestinal stroma tumor (HP:0100723)2.38479575
45Retrobulbar optic neuritis (HP:0100654)2.37912440
46Optic neuritis (HP:0100653)2.37912440
47Periodontitis (HP:0000704)2.37329023
48Epistaxis (HP:0000421)2.35958007
49Abnormality of liposaccharide metabolism (HP:0010968)2.33792184
50Abnormality of glycosphingolipid metabolism (HP:0004343)2.33792184
51Abnormality of glycolipid metabolism (HP:0010969)2.33792184
52Hematochezia (HP:0002573)2.33209191
53Panhypogammaglobulinemia (HP:0003139)2.33105359
54Abnormality of T cell physiology (HP:0011840)2.32489548
55Stomatitis (HP:0010280)2.30804332
56Abnormal platelet volume (HP:0011876)2.27594051
57Increased IgE level (HP:0003212)2.25693935
58Abnormality of glycosaminoglycan metabolism (HP:0004371)2.25321368
59Abnormality of mucopolysaccharide metabolism (HP:0011020)2.25321368
60Abnormality of polysaccharide metabolism (HP:0011012)2.25321368
61Systemic lupus erythematosus (HP:0002725)2.24715760
62Increased density of long bones (HP:0006392)2.22640790
63Hemorrhage of the eye (HP:0011885)2.18024847
64Granulocytopenia (HP:0001913)2.17880175
65Gingival bleeding (HP:0000225)2.16211281
66Aortic aneurysm (HP:0004942)2.15721747
67Pendular nystagmus (HP:0012043)2.14428621
68Meningitis (HP:0001287)2.14166567
69J-shaped sella turcica (HP:0002680)2.12445048
70Vertebral compression fractures (HP:0002953)2.11892239
71Abnormality of cells of the lymphoid lineage (HP:0012140)2.11213038
72Polygenic inheritance (HP:0010982)2.10713071
73Posterior subcapsular cataract (HP:0007787)2.08567828
74Lymphopenia (HP:0001888)2.08304749
75Emphysema (HP:0002097)2.07866866
76Loss of speech (HP:0002371)2.05574224
77Recurrent gram-negative bacterial infections (HP:0005420)2.03916691
78Hyperacusis (HP:0010780)2.03657625
79Pulmonary infiltrates (HP:0002113)2.03301812
80Hypertriglyceridemia (HP:0002155)2.02796922
81Dilatation of the ascending aorta (HP:0005111)2.02015393
82Agammaglobulinemia (HP:0004432)2.00475913
83Verrucae (HP:0200043)2.00381707
84Papilloma (HP:0012740)2.00381707
85Increased connective tissue (HP:0009025)1.98094375
86Amyloidosis (HP:0011034)1.97927348
87Purpura (HP:0000979)1.97598673
88Increased mean platelet volume (HP:0011877)1.96575826
89Hemoptysis (HP:0002105)1.95993605
90Encephalitis (HP:0002383)1.95970499
91Slow saccadic eye movements (HP:0000514)1.95710027
92Vasculitis (HP:0002633)1.94922053
93Segmental peripheral demyelination/remyelination (HP:0003481)1.94416676
94Osteomyelitis (HP:0002754)1.94342365
95Joint stiffness (HP:0001387)1.93950642
96Recurrent skin infections (HP:0001581)1.92685406
97Arterial thrombosis (HP:0004420)1.90596325
98Restrictive lung disease (HP:0002091)1.89538979
99Poikiloderma (HP:0001029)1.89489444
100Increased serum ferritin (HP:0003281)1.88313830
101Peritonitis (HP:0002586)1.86951623
102Ulnar bowing (HP:0003031)1.86685356
103Hypergammaglobulinemia (HP:0010702)1.85278768
104Chest pain (HP:0100749)1.85254429
105Abnormality of cells of the erythroid lineage (HP:0012130)1.84522123
106Keratoconjunctivitis sicca (HP:0001097)1.84443819
107Increased neuronal autofluorescent lipopigment (HP:0002074)1.83534344
108Hypertensive crisis (HP:0100735)1.83176201
109Recurrent cutaneous fungal infections (HP:0011370)1.82688620
110Chronic mucocutaneous candidiasis (HP:0002728)1.82688620
111Mediastinal lymphadenopathy (HP:0100721)1.81962812
112Polycythemia (HP:0001901)1.81742226
113Hepatosplenomegaly (HP:0001433)1.81713134
114Aneurysm (HP:0002617)1.81511010
115Myocardial infarction (HP:0001658)1.81174469
116Spondylolisthesis (HP:0003302)1.80323276
117Orchitis (HP:0100796)1.80082720
118Easy fatigability (HP:0003388)1.78984436
119Abnormality of the thoracic spine (HP:0100711)1.78789611
120Increased variability in muscle fiber diameter (HP:0003557)1.78010691
121Chorioretinal atrophy (HP:0000533)1.76848393
122Skin ulcer (HP:0200042)1.76831607
123Thoracic kyphosis (HP:0002942)1.76480139
124Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.75865414
125Abnormality of macrophages (HP:0004311)1.75818675
126Premature loss of primary teeth (HP:0006323)1.75711536
127Entropion (HP:0000621)1.74730736
128Dysostosis multiplex (HP:0000943)1.74317922
129Urticaria (HP:0001025)1.74154559
130Disproportionate tall stature (HP:0001519)1.73980708
131Abnormal number of erythroid precursors (HP:0012131)1.73717118
132Mucopolysacchariduria (HP:0008155)1.73386781
133Urinary glycosaminoglycan excretion (HP:0003541)1.73386781
134Cervical subluxation (HP:0003308)1.73327468
135Vacuolated lymphocytes (HP:0001922)1.71348021
136Microcytic anemia (HP:0001935)1.71233339
137Increased cerebral lipofuscin (HP:0011813)1.71068448
138High pitched voice (HP:0001620)1.70658404
139Basal cell carcinoma (HP:0002671)1.69134741
140Radial bowing (HP:0002986)1.65966587
141Ankle contracture (HP:0006466)1.65687664
142Reticulocytopenia (HP:0001896)1.65660083
143Fatigue (HP:0012378)1.65568120
144Scotoma (HP:0000575)1.65385672
145Thin bony cortex (HP:0002753)1.64595448
146Menorrhagia (HP:0000132)1.63924194
147Osteolytic defects of the hand bones (HP:0009699)1.63749869
148Osteolytic defects of the phalanges of the hand (HP:0009771)1.63749869
149Hypochromic anemia (HP:0001931)1.63580227

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K13.92429971
2PRPF4B3.47103470
3ERN13.34682700
4TRIB33.21206424
5MAP3K103.08932085
6RIPK42.78131580
7PKN22.74717159
8EEF2K2.66668815
9JAK32.18925506
10SMG12.16968092
11STK102.15646678
12TYK22.07875821
13MAP2K32.01184276
14ZAP701.88799549
15BTK1.85141853
16LRRK21.81526149
17FGFR41.72129790
18SIK11.68196875
19FLT31.67737291
20KIT1.65002028
21RPS6KA41.61551691
22TNK21.58706736
23TGFBR21.56317066
24CDK121.55485026
25TBK11.55422872
26PTK61.54458627
27GRK61.46952734
28BLK1.46742922
29ICK1.46576278
30TTN1.45327162
31CSF1R1.39788985
32TAOK31.39209496
33ITK1.37425371
34NME21.37165076
35KDR1.36910215
36NEK21.34894784
37CDC42BPA1.30500863
38JAK11.25572143
39MARK21.23243707
40SIK31.22821966
41TEC1.19023888
42CSK1.16519850
43EPHB11.14473508
44PASK1.12986398
45TGFBR11.12769471
46MAP3K11.12167440
47TXK1.10778821
48RIPK11.09661422
49MARK31.09125601
50TAOK21.07605939
51CDK41.01588660
52RPS6KB21.00268527
53IKBKE1.00070097
54PIM11.00044517
55SYK0.99052690
56MAP3K60.98142194
57MAP3K140.96757274
58SCYL20.94891986
59HCK0.91752880
60FGFR30.90662976
61MAPK120.89082439
62LCK0.87669726
63CDK60.86676356
64PDPK10.86205212
65SIK20.85107627
66HIPK20.84925445
67KSR20.84758622
68GRK10.84749373
69MAPK70.83389845
70MAP3K80.83077223
71IKBKB0.82508451
72PAK40.82099311
73MAP3K30.82051569
74JAK20.81659808
75CHUK0.81057871
76NEK90.79839903
77BCKDK0.77032478
78PDK10.74382237
79CAMKK10.74214587
80RPS6KL10.74074200
81RPS6KC10.74074200
82DYRK1B0.74074196
83IRAK20.70172056
84MAP3K70.70027189
85CAMK1D0.68713091
86RPS6KA20.67627102
87FGR0.65867689
88IRAK40.63651336
89MAP3K110.63605453
90NLK0.63579429
91MAP2K20.62559879
92MAP3K130.61713373
93PDGFRA0.60922879
94CDC70.60862425
95BRD40.59887321
96LYN0.59015850
97RET0.56020476
98PTK20.55794650
99MAPK110.55008331
100MTOR0.54727058
101FES0.54501353
102CDK90.53617227
103PAK20.52596865
104PRKD20.52386360
105ALK0.52087530
106IRAK10.51891841
107TESK10.51468881
108STK40.50469332
109TYRO30.50148894
110PRKCH0.49549559
111TIE10.49107134
112CLK10.48381360
113CDK70.48151333
114RPS6KA60.48042959
115BMX0.47693956
116IRAK30.47336792
117TRPM70.47112617
118MAPK40.45981485
119MAPKAPK20.45826745
120MAP2K60.45050448
121ACVR1B0.43918469
122TESK20.43769833
123MAPKAPK30.43337724
124TAOK10.42202940
125PRKG20.41862686
126PDGFRB0.40000697
127EPHA30.39280466
128STK380.39048192
129PIM20.38775350
130FYN0.38527385
131MATK0.38034675
132PRKD10.35386582

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053402.64361940
2B cell receptor signaling pathway_Homo sapiens_hsa046622.18090142
3Leishmaniasis_Homo sapiens_hsa051402.09533330
4Antigen processing and presentation_Homo sapiens_hsa046122.07866768
5Phototransduction_Homo sapiens_hsa047441.89264447
6NF-kappa B signaling pathway_Homo sapiens_hsa040641.85644030
7DNA replication_Homo sapiens_hsa030301.84408909
8Osteoclast differentiation_Homo sapiens_hsa043801.75997810
9Allograft rejection_Homo sapiens_hsa053301.74459283
10Measles_Homo sapiens_hsa051621.71460573
11Graft-versus-host disease_Homo sapiens_hsa053321.71301501
12Chronic myeloid leukemia_Homo sapiens_hsa052201.65025268
13Acute myeloid leukemia_Homo sapiens_hsa052211.60252724
14Autoimmune thyroid disease_Homo sapiens_hsa053201.59004230
15Staphylococcus aureus infection_Homo sapiens_hsa051501.55130337
16Toxoplasmosis_Homo sapiens_hsa051451.51714685
17Intestinal immune network for IgA production_Homo sapiens_hsa046721.47107382
18Ribosome_Homo sapiens_hsa030101.45768241
19Herpes simplex infection_Homo sapiens_hsa051681.44874685
20Caffeine metabolism_Homo sapiens_hsa002321.43465055
21Small cell lung cancer_Homo sapiens_hsa052221.42891011
22Hematopoietic cell lineage_Homo sapiens_hsa046401.39518051
23Leukocyte transendothelial migration_Homo sapiens_hsa046701.38621163
24Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.38405833
25Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.36235465
26Apoptosis_Homo sapiens_hsa042101.34137071
27Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.33279389
28Base excision repair_Homo sapiens_hsa034101.32071175
29Jak-STAT signaling pathway_Homo sapiens_hsa046301.30511468
30Shigellosis_Homo sapiens_hsa051311.30442288
31T cell receptor signaling pathway_Homo sapiens_hsa046601.28430020
32Other glycan degradation_Homo sapiens_hsa005111.26319855
33Toll-like receptor signaling pathway_Homo sapiens_hsa046201.24240186
34Glycosaminoglycan degradation_Homo sapiens_hsa005311.23796719
35Lysine degradation_Homo sapiens_hsa003101.22324145
36Hepatitis B_Homo sapiens_hsa051611.19667806
37RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.18406611
38Mismatch repair_Homo sapiens_hsa034301.15694616
39Platelet activation_Homo sapiens_hsa046111.14195894
40AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.12696051
41Influenza A_Homo sapiens_hsa051641.10498176
42Legionellosis_Homo sapiens_hsa051341.09750577
43Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.09211875
44Pancreatic cancer_Homo sapiens_hsa052121.07478947
45Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.06628871
46TNF signaling pathway_Homo sapiens_hsa046681.06454418
47Type I diabetes mellitus_Homo sapiens_hsa049401.06276275
48One carbon pool by folate_Homo sapiens_hsa006701.03235940
49NOD-like receptor signaling pathway_Homo sapiens_hsa046211.02694120
50Pentose phosphate pathway_Homo sapiens_hsa000301.02052470
51Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.99604692
52Phospholipase D signaling pathway_Homo sapiens_hsa040720.99599590
53Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.99583540
54Renal cell carcinoma_Homo sapiens_hsa052110.99179887
55Viral myocarditis_Homo sapiens_hsa054160.98774074
56HTLV-I infection_Homo sapiens_hsa051660.96740760
57Insulin resistance_Homo sapiens_hsa049310.96257268
58Sulfur relay system_Homo sapiens_hsa041220.95834788
59Asthma_Homo sapiens_hsa053100.95460624
60Non-small cell lung cancer_Homo sapiens_hsa052230.94662325
61Malaria_Homo sapiens_hsa051440.94228592
62Transcriptional misregulation in cancer_Homo sapiens_hsa052020.93814070
63p53 signaling pathway_Homo sapiens_hsa041150.92244957
64Cyanoamino acid metabolism_Homo sapiens_hsa004600.90326017
65Selenocompound metabolism_Homo sapiens_hsa004500.89830983
66Endometrial cancer_Homo sapiens_hsa052130.87896915
67GnRH signaling pathway_Homo sapiens_hsa049120.86929454
68ABC transporters_Homo sapiens_hsa020100.86922891
69Tuberculosis_Homo sapiens_hsa051520.85667485
70Notch signaling pathway_Homo sapiens_hsa043300.85325659
71Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.84610866
72Phosphatidylinositol signaling system_Homo sapiens_hsa040700.83701079
73Choline metabolism in cancer_Homo sapiens_hsa052310.83583518
74Spliceosome_Homo sapiens_hsa030400.82767354
75Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.82482802
76Viral carcinogenesis_Homo sapiens_hsa052030.81713972
77Prion diseases_Homo sapiens_hsa050200.81581368
78Chemokine signaling pathway_Homo sapiens_hsa040620.81511848
79Drug metabolism - other enzymes_Homo sapiens_hsa009830.79663525
80Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.78124891
81Central carbon metabolism in cancer_Homo sapiens_hsa052300.76275404
82Complement and coagulation cascades_Homo sapiens_hsa046100.76182328
83Salmonella infection_Homo sapiens_hsa051320.76069852
84Sphingolipid signaling pathway_Homo sapiens_hsa040710.76052836
85Pertussis_Homo sapiens_hsa051330.75764817
86Epstein-Barr virus infection_Homo sapiens_hsa051690.75754801
87VEGF signaling pathway_Homo sapiens_hsa043700.74471435
88Phagosome_Homo sapiens_hsa041450.74333883
89Endocytosis_Homo sapiens_hsa041440.73187468
90Neurotrophin signaling pathway_Homo sapiens_hsa047220.71753219
91Proteoglycans in cancer_Homo sapiens_hsa052050.71568431
92Inositol phosphate metabolism_Homo sapiens_hsa005620.71206456
93Lysosome_Homo sapiens_hsa041420.70364667
94Focal adhesion_Homo sapiens_hsa045100.68673261
95Hepatitis C_Homo sapiens_hsa051600.68180013
96Adipocytokine signaling pathway_Homo sapiens_hsa049200.68058456
97Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.67881798
98African trypanosomiasis_Homo sapiens_hsa051430.66641437
99Glioma_Homo sapiens_hsa052140.66112486
100ErbB signaling pathway_Homo sapiens_hsa040120.66023256
101N-Glycan biosynthesis_Homo sapiens_hsa005100.65702820
102Insulin signaling pathway_Homo sapiens_hsa049100.65639063
103Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.65615426
104Rheumatoid arthritis_Homo sapiens_hsa053230.65007357
105mTOR signaling pathway_Homo sapiens_hsa041500.64227421
106Prolactin signaling pathway_Homo sapiens_hsa049170.64133834
107Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.62913934
108Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.62698548
109Prostate cancer_Homo sapiens_hsa052150.60569684
110Fatty acid degradation_Homo sapiens_hsa000710.60140846
111Longevity regulating pathway - mammal_Homo sapiens_hsa042110.59936073
112Cell cycle_Homo sapiens_hsa041100.59617958
113Estrogen signaling pathway_Homo sapiens_hsa049150.58852068
114HIF-1 signaling pathway_Homo sapiens_hsa040660.58760268
115Thyroid hormone signaling pathway_Homo sapiens_hsa049190.58570372
116FoxO signaling pathway_Homo sapiens_hsa040680.58279445
117MicroRNAs in cancer_Homo sapiens_hsa052060.57343018
118MAPK signaling pathway_Homo sapiens_hsa040100.57183548
119Bladder cancer_Homo sapiens_hsa052190.56728158
120Maturity onset diabetes of the young_Homo sapiens_hsa049500.56316710
121Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.56253489
122Fructose and mannose metabolism_Homo sapiens_hsa000510.55255287
123Glycerophospholipid metabolism_Homo sapiens_hsa005640.53491407
124Colorectal cancer_Homo sapiens_hsa052100.52905107
125ECM-receptor interaction_Homo sapiens_hsa045120.52002558
126Pentose and glucuronate interconversions_Homo sapiens_hsa000400.51968957
127Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.50675991
128Amoebiasis_Homo sapiens_hsa051460.49367488
129Thyroid cancer_Homo sapiens_hsa052160.48250145
130Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.48000288
131Galactose metabolism_Homo sapiens_hsa000520.47017800
132Carbohydrate digestion and absorption_Homo sapiens_hsa049730.46241939
133Nitrogen metabolism_Homo sapiens_hsa009100.45019855

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