EME1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA strand elongation involved in DNA replication (GO:0006271)4.90821577
2telomere maintenance via semi-conservative replication (GO:0032201)4.85116022
3viral transcription (GO:0019083)4.68851660
4DNA strand elongation (GO:0022616)4.65671594
5DNA replication checkpoint (GO:0000076)4.64176732
6translational termination (GO:0006415)4.54961914
7DNA replication initiation (GO:0006270)4.46774937
8maturation of SSU-rRNA (GO:0030490)4.46690614
9protein localization to kinetochore (GO:0034501)4.40298155
10kinetochore organization (GO:0051383)4.37464000
11mitotic metaphase plate congression (GO:0007080)4.36951297
12telomere maintenance via recombination (GO:0000722)4.36326011
13ribosomal large subunit biogenesis (GO:0042273)4.34262017
14mitotic recombination (GO:0006312)4.29170397
15kinetochore assembly (GO:0051382)4.18438990
16DNA unwinding involved in DNA replication (GO:0006268)4.18150836
17DNA deamination (GO:0045006)4.12947585
18telomere maintenance via telomere lengthening (GO:0010833)4.05921867
19mitotic sister chromatid segregation (GO:0000070)4.04615734
20translational elongation (GO:0006414)4.01752988
21ribosomal small subunit assembly (GO:0000028)4.01676020
22ribosomal small subunit biogenesis (GO:0042274)3.99908467
23chromatin remodeling at centromere (GO:0031055)3.95344889
24CENP-A containing nucleosome assembly (GO:0034080)3.94859863
25translational initiation (GO:0006413)3.93994323
26protein localization to chromosome, centromeric region (GO:0071459)3.92401238
27SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.86540237
28nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.79902448
29spliceosomal snRNP assembly (GO:0000387)3.78979921
30cotranslational protein targeting to membrane (GO:0006613)3.77774104
31nucleotide-excision repair, DNA gap filling (GO:0006297)3.76531963
32protein targeting to ER (GO:0045047)3.75752824
33metaphase plate congression (GO:0051310)3.72942963
34formation of translation preinitiation complex (GO:0001731)3.70285575
35cellular protein complex disassembly (GO:0043624)3.66230984
36mitotic nuclear envelope disassembly (GO:0007077)3.65725923
37intra-S DNA damage checkpoint (GO:0031573)3.65202177
38DNA topological change (GO:0006265)3.62089323
39ribonucleoprotein complex biogenesis (GO:0022613)3.61917038
40DNA replication-dependent nucleosome organization (GO:0034723)3.60771243
41DNA replication-dependent nucleosome assembly (GO:0006335)3.60771243
42sister chromatid segregation (GO:0000819)3.59694027
43DNA strand renaturation (GO:0000733)3.58934256
44spliceosomal complex assembly (GO:0000245)3.58592841
45attachment of spindle microtubules to kinetochore (GO:0008608)3.56122538
46regulation of spindle organization (GO:0090224)3.56113473
47viral life cycle (GO:0019058)3.55831851
48establishment of protein localization to endoplasmic reticulum (GO:0072599)3.53996219
49regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.52554091
50establishment of protein localization to mitochondrial membrane (GO:0090151)3.52060400
51mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.50411796
52DNA replication-independent nucleosome organization (GO:0034724)3.49988662
53DNA replication-independent nucleosome assembly (GO:0006336)3.49988662
54nucleobase biosynthetic process (GO:0046112)3.49715406
55protein localization to endoplasmic reticulum (GO:0070972)3.48224125
56DNA ligation (GO:0006266)3.45301540
57establishment of chromosome localization (GO:0051303)3.44423003
58proteasome assembly (GO:0043248)3.41618296
59nuclear pore complex assembly (GO:0051292)3.41201549
60transcription-coupled nucleotide-excision repair (GO:0006283)3.39414223
61mitotic chromosome condensation (GO:0007076)3.37801641
62replication fork processing (GO:0031297)3.36773957
63regulation of mitochondrial translation (GO:0070129)3.34787377
64regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.34288853
65rRNA processing (GO:0006364)3.34017432
66membrane disassembly (GO:0030397)3.33501084
67nuclear envelope disassembly (GO:0051081)3.33501084
68protein complex disassembly (GO:0043241)3.32526228
69regulation of double-strand break repair via homologous recombination (GO:0010569)3.32032966
70establishment of integrated proviral latency (GO:0075713)3.30920568
71folic acid-containing compound biosynthetic process (GO:0009396)3.30872563
72protein K6-linked ubiquitination (GO:0085020)3.28960827
73regulation of translational fidelity (GO:0006450)3.28187818
74histone exchange (GO:0043486)3.27716702
75ribosome biogenesis (GO:0042254)3.25221059
76purine nucleobase biosynthetic process (GO:0009113)3.25206350
77rRNA modification (GO:0000154)3.23966833
78rRNA metabolic process (GO:0016072)3.23098603
79resolution of meiotic recombination intermediates (GO:0000712)3.21750082
80positive regulation of chromosome segregation (GO:0051984)3.21089325
81rRNA methylation (GO:0031167)3.20277782
82regulation of centriole replication (GO:0046599)3.20009858
83spindle checkpoint (GO:0031577)3.19786464
84negative regulation of chromosome segregation (GO:0051985)3.19681777
85IMP biosynthetic process (GO:0006188)3.18664524
86meiotic chromosome segregation (GO:0045132)3.17671608
87energy coupled proton transport, down electrochemical gradient (GO:0015985)3.17548570
88ATP synthesis coupled proton transport (GO:0015986)3.17548570
89macromolecular complex disassembly (GO:0032984)3.16576928
90viral mRNA export from host cell nucleus (GO:0046784)3.14816236
91anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.13742588
92base-excision repair (GO:0006284)3.12703255
93regulation of mitotic metaphase/anaphase transition (GO:0030071)3.11982781
94translation (GO:0006412)3.11953898
95regulation of mitotic spindle organization (GO:0060236)3.10676244
96negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.10247563
97negative regulation of sister chromatid segregation (GO:0033046)3.10247563
98negative regulation of mitotic sister chromatid separation (GO:2000816)3.10247563
99negative regulation of mitotic sister chromatid segregation (GO:0033048)3.10247563
100chaperone-mediated protein transport (GO:0072321)3.09011802
101maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.08475833
102spindle assembly checkpoint (GO:0071173)3.08373048
103regulation of chromosome segregation (GO:0051983)3.06890968
104nuclear-transcribed mRNA catabolic process (GO:0000956)3.05468089
105regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.05169051
106chromatin assembly or disassembly (GO:0006333)3.04536080
107mitotic spindle assembly checkpoint (GO:0007094)3.03869462
108L-serine metabolic process (GO:0006563)3.03477044
109cellular component biogenesis (GO:0044085)3.02839426
110negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.01480831
111regulation of DNA endoreduplication (GO:0032875)3.01195564
112heterochromatin organization (GO:0070828)3.01078405
113deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.01015795
114mitotic spindle checkpoint (GO:0071174)3.00823726
115nuclear pore organization (GO:0006999)2.99623713
116transcription elongation from RNA polymerase III promoter (GO:0006385)2.99551623
117termination of RNA polymerase III transcription (GO:0006386)2.99551623
118negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.99371116
119mitotic sister chromatid cohesion (GO:0007064)2.98920442
120pseudouridine synthesis (GO:0001522)2.98839423
121mismatch repair (GO:0006298)2.97638065
122regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.96945073
123chromosome condensation (GO:0030261)2.96685104
124telomere organization (GO:0032200)2.96461919
125chromosome segregation (GO:0007059)2.95728231
126DNA catabolic process, exonucleolytic (GO:0000738)2.92316097
127regulation of centrosome cycle (GO:0046605)2.87997993
128microtubule depolymerization (GO:0007019)2.87226231

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.79215408
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.96993443
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.41469351
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.95510801
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.66222509
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.46858678
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.41205243
8MYC_19079543_ChIP-ChIP_MESCs_Mouse3.17989591
9EST1_17652178_ChIP-ChIP_JURKAT_Human3.01466814
10ETS1_20019798_ChIP-Seq_JURKAT_Human2.91698310
11MYC_19030024_ChIP-ChIP_MESCs_Mouse2.90579115
12* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.88456367
13* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.83362255
14GABP_17652178_ChIP-ChIP_JURKAT_Human2.80505109
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.71109263
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.69485401
17* XRN2_22483619_ChIP-Seq_HELA_Human2.44471899
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.39416689
19SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.37117530
20MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.31117928
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.27810143
22NELFA_20434984_ChIP-Seq_ESCs_Mouse2.24160828
23MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.11876522
24VDR_23849224_ChIP-Seq_CD4+_Human2.07988838
25DCP1A_22483619_ChIP-Seq_HELA_Human2.07168410
26* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.04291022
27E2F1_21310950_ChIP-Seq_MCF-7_Human2.00686227
28TTF2_22483619_ChIP-Seq_HELA_Human1.97446458
29HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.92808930
30AR_21909140_ChIP-Seq_LNCAP_Human1.90280077
31FOXP3_21729870_ChIP-Seq_TREG_Human1.90123494
32HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.88966158
33THAP11_20581084_ChIP-Seq_MESCs_Mouse1.88873382
34NANOG_18555785_ChIP-Seq_MESCs_Mouse1.87125473
35E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.83677554
36* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.82531515
37CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.80428208
38GABP_19822575_ChIP-Seq_HepG2_Human1.80414068
39POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.78845920
40ELF1_17652178_ChIP-ChIP_JURKAT_Human1.68119955
41YY1_21170310_ChIP-Seq_MESCs_Mouse1.66687143
42TP63_19390658_ChIP-ChIP_HaCaT_Human1.62816976
43* MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.61445263
44ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.58206954
45* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.55456392
46SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.55059157
47* ELK1_19687146_ChIP-ChIP_HELA_Human1.49124431
48KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.47235090
49YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.46778995
50POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.43583237
51SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.43031865
52PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.42701089
53CIITA_25753668_ChIP-Seq_RAJI_Human1.42665921
54ZFX_18555785_ChIP-Seq_MESCs_Mouse1.42524083
55FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.41408528
56TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.37772415
57* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.37194944
58KDM5A_27292631_Chip-Seq_BREAST_Human1.35730242
59SOX2_18555785_ChIP-Seq_MESCs_Mouse1.35110643
60HOXB4_20404135_ChIP-ChIP_EML_Mouse1.28614854
61EGR1_19374776_ChIP-ChIP_THP-1_Human1.26537763
62SRF_21415370_ChIP-Seq_HL-1_Mouse1.24284823
63ESR1_15608294_ChIP-ChIP_MCF-7_Human1.23716059
64POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.20391625
65CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.20252444
66STAT3_1855785_ChIP-Seq_MESCs_Mouse1.19889024
67* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.18651459
68MYC_18940864_ChIP-ChIP_HL60_Human1.16495980
69TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.16386632
70KLF4_18555785_ChIP-Seq_MESCs_Mouse1.15260341
71E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.13626822
72MYC_22102868_ChIP-Seq_BL_Human1.11264380
73KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.10953848
74KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.10953848
75KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.10953848
76SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.10832710
77KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.10418572
78ERG_20887958_ChIP-Seq_HPC-7_Mouse1.06011295
79FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.05745038
80RBPJ_22232070_ChIP-Seq_NCS_Mouse1.04753519
81TCF3_18692474_ChIP-Seq_MEFs_Mouse1.04682927
82ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.01996879
83VDR_21846776_ChIP-Seq_THP-1_Human1.01314872
84CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.01177785
85PADI4_21655091_ChIP-ChIP_MCF-7_Human0.98300723
86TFEB_21752829_ChIP-Seq_HELA_Human0.97002212
87SOX2_18692474_ChIP-Seq_MEFs_Mouse0.95635416
88BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.95557715
89ZNF263_19887448_ChIP-Seq_K562_Human0.94645280
90FOXP1_21924763_ChIP-Seq_HESCs_Human0.93123895
91NANOG_21062744_ChIP-ChIP_HESCs_Human0.91571150
92PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.91487249
93* ELK1_22589737_ChIP-Seq_MCF10A_Human0.91478530
94ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.90485082
95OCT4_18692474_ChIP-Seq_MEFs_Mouse0.89784150
96NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.89664112
97SOX2_16153702_ChIP-ChIP_HESCs_Human0.88890225
98ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.88414858
99CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.86288358
100SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.85820048
101SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.85714831
102CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.85082186
103CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.84546397
104GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.84391952
105NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.83885870
106CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.83811174
107* NANOG_16153702_ChIP-ChIP_HESCs_Human0.82698941
108CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.81388488
109PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.80373227
110TCF3_18692474_ChIP-Seq_MESCs_Mouse0.78962281
111TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.78952076
112SOX17_20123909_ChIP-Seq_XEN_Mouse0.77580885
113SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.76797992
114TBX5_21415370_ChIP-Seq_HL-1_Mouse0.75652710
115TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.74585061
116IRF1_19129219_ChIP-ChIP_H3396_Human0.74183103
117HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.73767971
118CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.73195150
119SALL1_21062744_ChIP-ChIP_HESCs_Human0.68421772

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.61806153
2MP0003111_abnormal_nucleus_morphology4.69966697
3MP0010094_abnormal_chromosome_stability4.59965265
4MP0004957_abnormal_blastocyst_morpholog4.37250946
5MP0003077_abnormal_cell_cycle4.12453858
6MP0008057_abnormal_DNA_replication3.88923667
7MP0008058_abnormal_DNA_repair3.55065820
8MP0008932_abnormal_embryonic_tissue3.17449593
9MP0008007_abnormal_cellular_replicative2.78825642
10MP0000350_abnormal_cell_proliferation2.24682725
11MP0003123_paternal_imprinting2.22315741
12MP0001730_embryonic_growth_arrest2.20455410
13MP0010030_abnormal_orbit_morphology2.15007881
14MP0003786_premature_aging2.06172031
15MP0003806_abnormal_nucleotide_metabolis2.02029626
16MP0003718_maternal_effect2.00390533
17MP0006292_abnormal_olfactory_placode1.91016833
18MP0002396_abnormal_hematopoietic_system1.83414556
19MP0008877_abnormal_DNA_methylation1.83075380
20MP0004233_abnormal_muscle_weight1.76790842
21MP0003315_abnormal_perineum_morphology1.75450784
22MP0009379_abnormal_foot_pigmentation1.71153110
23MP0001697_abnormal_embryo_size1.65810825
24MP0005380_embryogenesis_phenotype1.65287068
25MP0001672_abnormal_embryogenesis/_devel1.65287068
26MP0002085_abnormal_embryonic_tissue1.63877417
27MP0000490_abnormal_crypts_of1.61416645
28MP0002163_abnormal_gland_morphology1.50892383
29MP0002080_prenatal_lethality1.50775409
30MP0001293_anophthalmia1.43698217
31MP0000313_abnormal_cell_death1.42088597
32MP0002234_abnormal_pharynx_morphology1.41478235
33MP0009697_abnormal_copulation1.41084398
34MP0002084_abnormal_developmental_patter1.39282034
35MP0002019_abnormal_tumor_incidence1.36893964
36MP0006035_abnormal_mitochondrial_morpho1.35483402
37MP0004133_heterotaxia1.35466535
38MP0003984_embryonic_growth_retardation1.34214724
39MP0002088_abnormal_embryonic_growth/wei1.33186455
40MP0006036_abnormal_mitochondrial_physio1.33003887
41MP0008995_early_reproductive_senescence1.32639886
42MP0003890_abnormal_embryonic-extraembry1.29907393
43MP0000566_synostosis1.26737395
44MP0010307_abnormal_tumor_latency1.26081086
45MP0000049_abnormal_middle_ear1.25069572
46MP0002653_abnormal_ependyma_morphology1.21054375
47MP0009333_abnormal_splenocyte_physiolog1.20300292
48MP0009053_abnormal_anal_canal1.20143772
49MP0002210_abnormal_sex_determination1.19729431
50MP0004197_abnormal_fetal_growth/weight/1.19646855
51MP0003121_genomic_imprinting1.19150579
52MP0005076_abnormal_cell_differentiation1.18713970
53MP0002697_abnormal_eye_size1.18497007
54MP0002086_abnormal_extraembryonic_tissu1.18195828
55MP0003119_abnormal_digestive_system1.16170398
56MP0002102_abnormal_ear_morphology1.14622659
57MP0003567_abnormal_fetal_cardiomyocyte1.14427477
58MP0003941_abnormal_skin_development1.14167515
59MP0003937_abnormal_limbs/digits/tail_de1.14030825
60MP0003136_yellow_coat_color1.13883790
61MP0001346_abnormal_lacrimal_gland1.10239214
62MP0010352_gastrointestinal_tract_polyps1.06658027
63MP0002111_abnormal_tail_morphology1.05647630
64MP0001145_abnormal_male_reproductive1.03632863
65MP0000015_abnormal_ear_pigmentation1.02089151
66MP0005394_taste/olfaction_phenotype1.01292937
67MP0005499_abnormal_olfactory_system1.01292937
68MP0002160_abnormal_reproductive_system1.00680359
69MP0002233_abnormal_nose_morphology1.00538632
70MP0005257_abnormal_intraocular_pressure0.99124441
71MP0001529_abnormal_vocalization0.97568441
72MP0002938_white_spotting0.96877837
73MP0005084_abnormal_gallbladder_morpholo0.96866024
74MP0002751_abnormal_autonomic_nervous0.96582274
75MP0003938_abnormal_ear_development0.95505368
76MP0000428_abnormal_craniofacial_morphol0.94221417
77MP0005171_absent_coat_pigmentation0.93506439
78MP0005174_abnormal_tail_pigmentation0.92426800
79MP0005408_hypopigmentation0.92032092
80MP0000858_altered_metastatic_potential0.91801549
81MP0004808_abnormal_hematopoietic_stem0.90885887
82MP0001188_hyperpigmentation0.88310893
83MP0003186_abnormal_redox_activity0.86998895
84MP0000372_irregular_coat_pigmentation0.86666816
85MP0004147_increased_porphyrin_level0.86588424
86MP0001286_abnormal_eye_development0.86156975
87MP0005389_reproductive_system_phenotype0.86037338
88MP0000653_abnormal_sex_gland0.85131506
89MP0000537_abnormal_urethra_morphology0.83711904
90MP0000703_abnormal_thymus_morphology0.82543928
91MP0009672_abnormal_birth_weight0.82418410
92MP0009250_abnormal_appendicular_skeleto0.82401775
93MP0001929_abnormal_gametogenesis0.80200363
94MP0003755_abnormal_palate_morphology0.80091238
95MP0002249_abnormal_larynx_morphology0.78757082
96MP0006072_abnormal_retinal_apoptosis0.78422544
97MP0002132_abnormal_respiratory_system0.77858912
98MP0003698_abnormal_male_reproductive0.77576900
99MP0001119_abnormal_female_reproductive0.76525511
100MP0000613_abnormal_salivary_gland0.76359221
101MP0001919_abnormal_reproductive_system0.74882424
102MP0002177_abnormal_outer_ear0.74522482
103MP0001764_abnormal_homeostasis0.74457049
104MP0003942_abnormal_urinary_system0.74221732
105MP0000678_abnormal_parathyroid_gland0.74096916
106MP0002932_abnormal_joint_morphology0.73903992
107MP0003385_abnormal_body_wall0.73497943
108MP0003943_abnormal_hepatobiliary_system0.71531922
109MP0004185_abnormal_adipocyte_glucose0.70565925
110MP0002877_abnormal_melanocyte_morpholog0.70272591
111MP0002095_abnormal_skin_pigmentation0.68698889
112MP0005397_hematopoietic_system_phenotyp0.68565025
113MP0001545_abnormal_hematopoietic_system0.68565025
114MP0003935_abnormal_craniofacial_develop0.68089195
115MP0000432_abnormal_head_morphology0.67926396
116MP0002114_abnormal_axial_skeleton0.67692529
117MP0000358_abnormal_cell_content/0.67558330
118MP0002161_abnormal_fertility/fecundity0.67120701
119MP0003861_abnormal_nervous_system0.66435626
120MP0005423_abnormal_somatic_nervous0.66240383
121MP0002092_abnormal_eye_morphology0.66034954
122MP0009278_abnormal_bone_marrow0.64903072
123MP0008789_abnormal_olfactory_epithelium0.64655446
124MP0002722_abnormal_immune_system0.64417157
125MP0005075_abnormal_melanosome_morpholog0.64247265
126MP0001324_abnormal_eye_pigmentation0.64163236
127MP0002398_abnormal_bone_marrow0.63976741
128MP0003699_abnormal_female_reproductive0.63414978
129MP0002282_abnormal_trachea_morphology0.63317938
130MP0005384_cellular_phenotype0.62367983
131MP0003448_altered_tumor_morphology0.62254891
132MP0005501_abnormal_skin_physiology0.61741450
133MP0000689_abnormal_spleen_morphology0.61504280
134MP0009703_decreased_birth_body0.61440403

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)5.21460841
2Chromsome breakage (HP:0040012)4.21895906
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.19916129
4Breast hypoplasia (HP:0003187)4.19286873
5Carpal bone hypoplasia (HP:0001498)4.08153092
6Birth length less than 3rd percentile (HP:0003561)4.03071368
7Abnormality of cells of the erythroid lineage (HP:0012130)3.89473254
8Patellar aplasia (HP:0006443)3.68437618
9Aplasia/Hypoplasia of the patella (HP:0006498)3.60513165
10Abnormal number of erythroid precursors (HP:0012131)3.56031495
11Macrocytic anemia (HP:0001972)3.41547255
12Absent radius (HP:0003974)3.40250650
13Aplasia/Hypoplasia of the sacrum (HP:0008517)3.36000753
14Meckel diverticulum (HP:0002245)3.32276523
15Oral leukoplakia (HP:0002745)3.29964784
16Abnormality of the ileum (HP:0001549)3.26538550
17Pallor (HP:0000980)3.22518980
18Aplasia involving forearm bones (HP:0009822)3.17760632
19Absent forearm bone (HP:0003953)3.17760632
20Colon cancer (HP:0003003)3.16360974
21Abnormality of the preputium (HP:0100587)3.16317386
22Abnormal mitochondria in muscle tissue (HP:0008316)3.16276671
23Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.13924388
24Rough bone trabeculation (HP:0100670)3.08926383
25Acute necrotizing encephalopathy (HP:0006965)3.04670341
26Absent thumb (HP:0009777)3.03209875
27Selective tooth agenesis (HP:0001592)2.99713251
28Abnormal number of incisors (HP:0011064)2.96669805
29Aplasia/Hypoplasia of the uvula (HP:0010293)2.96139836
30Increased hepatocellular lipid droplets (HP:0006565)2.93174744
31Triphalangeal thumb (HP:0001199)2.92094074
32Abnormality of chromosome stability (HP:0003220)2.89060700
33Acute encephalopathy (HP:0006846)2.87593657
34Horseshoe kidney (HP:0000085)2.82797854
35Concave nail (HP:0001598)2.78079884
36Impulsivity (HP:0100710)2.75312211
37Mitochondrial inheritance (HP:0001427)2.74747424
38Increased CSF lactate (HP:0002490)2.73508624
39Abnormality of the labia minora (HP:0012880)2.72760999
40Abnormality of the anterior horn cell (HP:0006802)2.69196086
41Degeneration of anterior horn cells (HP:0002398)2.69196086
42Premature graying of hair (HP:0002216)2.68779293
43Lipid accumulation in hepatocytes (HP:0006561)2.65173873
44Duodenal stenosis (HP:0100867)2.63908961
45Small intestinal stenosis (HP:0012848)2.63908961
46Medulloblastoma (HP:0002885)2.60043959
47Rhabdomyosarcoma (HP:0002859)2.57783745
48Supernumerary spleens (HP:0009799)2.57354871
49Ependymoma (HP:0002888)2.55574169
50Hepatocellular necrosis (HP:0001404)2.52980898
51Abnormality of DNA repair (HP:0003254)2.52214455
52Type 2 muscle fiber atrophy (HP:0003554)2.48174174
53Trismus (HP:0000211)2.48089179
54Tracheoesophageal fistula (HP:0002575)2.47964555
55Neoplasm of the pancreas (HP:0002894)2.43444006
56Muscle fiber atrophy (HP:0100295)2.41256177
57Duplicated collecting system (HP:0000081)2.40826901
58Agnosia (HP:0010524)2.38139299
59Cerebral hypomyelination (HP:0006808)2.36955554
60Bone marrow hypocellularity (HP:0005528)2.36863431
61Abnormal lung lobation (HP:0002101)2.36805977
62Poikiloderma (HP:0001029)2.36264628
63Myelodysplasia (HP:0002863)2.34283101
64Renal Fanconi syndrome (HP:0001994)2.33484265
65Ectopic kidney (HP:0000086)2.31677581
66Atresia of the external auditory canal (HP:0000413)2.31644830
67Increased intramyocellular lipid droplets (HP:0012240)2.26719035
68Abnormality of cochlea (HP:0000375)2.24525803
69Cleft eyelid (HP:0000625)2.23437553
70Sloping forehead (HP:0000340)2.22802572
71Aplastic anemia (HP:0001915)2.22010914
72Abnormal trabecular bone morphology (HP:0100671)2.21679064
73Abnormality of the duodenum (HP:0002246)2.20668748
74Progressive macrocephaly (HP:0004481)2.18793141
7511 pairs of ribs (HP:0000878)2.18727538
76Increased serum lactate (HP:0002151)2.18232505
77Hepatic necrosis (HP:0002605)2.16671407
78Nephroblastoma (Wilms tumor) (HP:0002667)2.15938783
79Hypoplasia of the radius (HP:0002984)2.15714466
80Abnormal hemoglobin (HP:0011902)2.12560766
81Microvesicular hepatic steatosis (HP:0001414)2.10061945
82Secondary amenorrhea (HP:0000869)2.09775145
83Clubbing of toes (HP:0100760)2.08879642
84Cellular immunodeficiency (HP:0005374)2.07705756
85Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.06247475
86Decreased activity of mitochondrial respiratory chain (HP:0008972)2.06247475
87Abnormality of the renal collecting system (HP:0004742)2.04044470
88Abdominal situs inversus (HP:0003363)2.01825347
89Abnormality of abdominal situs (HP:0011620)2.01825347
90Premature ovarian failure (HP:0008209)2.01501056
91Cerebral edema (HP:0002181)2.00884376
92Basal cell carcinoma (HP:0002671)1.99856216
93Embryonal renal neoplasm (HP:0011794)1.98687217
94Type I transferrin isoform profile (HP:0003642)1.96774190
95Abnormality of pyrimidine metabolism (HP:0004353)1.94713204
96Increased serum pyruvate (HP:0003542)1.93343062
97Short thumb (HP:0009778)1.92789095
98Abnormal sex determination (HP:0012244)1.92483812
99Sex reversal (HP:0012245)1.92483812
100Abnormality of the pons (HP:0007361)1.92133937
101Abnormality of glycolysis (HP:0004366)1.90033255
102Hypoplasia of the pons (HP:0012110)1.89907659
103Exercise intolerance (HP:0003546)1.88923112
104Facial cleft (HP:0002006)1.86904093
105Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.86445020
106Abnormality of reticulocytes (HP:0004312)1.85886072
107Microretrognathia (HP:0000308)1.84996377
108Lactic acidosis (HP:0003128)1.84346105
109Hypoplastic pelvis (HP:0008839)1.83135846
110Respiratory difficulties (HP:0002880)1.81062997
111Rib fusion (HP:0000902)1.80327091
112Aplasia/hypoplasia of the humerus (HP:0006507)1.79976905
113Abnormality of the carotid arteries (HP:0005344)1.78929104
114Increased muscle lipid content (HP:0009058)1.78916041
115Duplication of thumb phalanx (HP:0009942)1.78847397
116Abnormality of renal resorption (HP:0011038)1.78131525
117Volvulus (HP:0002580)1.76589655
118Increased nuchal translucency (HP:0010880)1.76121156
119Aplasia/Hypoplasia of the earlobes (HP:0009906)1.75053880
120Diastasis recti (HP:0001540)1.74897319
121Abnormality of homocysteine metabolism (HP:0010919)1.74668092
122Homocystinuria (HP:0002156)1.74668092
123Tetralogy of Fallot (HP:0001636)1.73882915
124Neoplasm of striated muscle (HP:0009728)1.73682470
125Facial hemangioma (HP:0000329)1.73266884
126Progressive muscle weakness (HP:0003323)1.73036233
127Vaginal fistula (HP:0004320)1.72858649
128Hypoplasia of the capital femoral epiphysis (HP:0003090)1.72203096
129Cortical dysplasia (HP:0002539)1.71173160
130Squamous cell carcinoma (HP:0002860)1.71169800
131Holoprosencephaly (HP:0001360)1.70964029
132Broad alveolar ridges (HP:0000187)1.69111971
133Sclerocornea (HP:0000647)1.69090620
134Pancytopenia (HP:0001876)1.67664180
135Exertional dyspnea (HP:0002875)1.67045592
136High anterior hairline (HP:0009890)1.66955795
137Cafe-au-lait spot (HP:0000957)1.66836693
138Depressed nasal ridge (HP:0000457)1.66311319
139Multiple enchondromatosis (HP:0005701)1.65443580
140Rectal fistula (HP:0100590)1.64411929
141Rectovaginal fistula (HP:0000143)1.64411929
142Neoplasm of the colon (HP:0100273)1.63785366
143Choanal atresia (HP:0000453)1.62348008

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.87435092
2TLK14.53925238
3WEE14.04810575
4VRK23.56189477
5CDC73.49244037
6EIF2AK13.21327284
7NME22.69501993
8SRPK12.61015713
9NEK22.48269230
10TTK2.40754917
11PLK12.18954594
12TAF12.09455491
13MKNK22.08393828
14TESK22.06732404
15PLK42.06179853
16BRSK22.03251982
17STK161.90367532
18DYRK31.89925984
19VRK11.88779234
20MKNK11.88006042
21RPS6KA41.81674308
22CDK71.75833943
23AURKB1.70138116
24BRSK11.67040881
25AURKA1.56325702
26CHEK21.55115445
27SMG11.53267226
28TSSK61.53161144
29PLK31.48509594
30ATR1.44884085
31NEK11.42956380
32PDK21.30223941
33EIF2AK31.27962031
34MAP3K101.23911739
35CDK41.22963635
36MAP3K81.22574173
37PASK1.19426132
38NUAK11.16738541
39CCNB11.15731095
40RPS6KB21.15695235
41CHEK11.15321271
42PBK1.12541559
43EPHA21.09489331
44PIM21.09216135
45ACVR1B1.07304922
46BRAF1.07156616
47MAP3K111.04176038
48STK41.03759866
49CDK121.01962843
50ARAF0.98526979
51PNCK0.97252458
52WNK40.96896643
53STK100.96126075
54BCKDK0.89106025
55CDK80.84871993
56CDK20.83837530
57LATS20.82555894
58ATM0.80562082
59CSNK2A10.80127235
60BLK0.79419179
61PAK10.79385276
62YES10.77259826
63MST40.76575061
64CSNK2A20.76078258
65MELK0.75995794
66CSNK1G30.73132524
67EIF2AK20.72103148
68PAK40.68990210
69UHMK10.67579098
70PIM10.67243304
71CDK10.65995671
72CDK60.64485382
73RPS6KA50.63659236
74ZAK0.62408264
75CSNK1A1L0.62269943
76PRKCI0.62139429
77MAPKAPK50.61400605
78DYRK20.59895114
79TESK10.59873641
80MUSK0.57522456
81CDK150.55818283
82NME10.55295503
83CSNK1G10.54444051
84CLK10.54096710
85STK38L0.52237739
86CDK180.51393592
87TAOK20.50892129
88BMPR1B0.50644422
89MAPK150.50605979
90CSNK1G20.49982375
91SCYL20.47993951
92CDK140.47742545
93NEK90.46206770
94ABL20.45049707
95ALK0.43756993
96AKT30.42588053
97RPS6KL10.39606899
98RPS6KC10.39606899
99CDK30.39034896
100IRAK30.38936558
101CDK90.38791531
102BRD40.37511210
103CSNK1E0.35456505
104PRKDC0.34646226
105CAMK1G0.32500604
106MST1R0.32426036
107CAMK1D0.32368374
108DAPK30.31347135
109RAF10.31309702
110IRAK40.31171225
111EPHB20.30556060
112ICK0.30537181
113RPS6KA60.30120292
114AKT20.28967343
115KDR0.28306809
116MAPK140.27379994
117PLK20.26769226
118CDK11A0.26635556
119IKBKB0.26169901
120RPS6KA10.25565739
121CDK190.25102491
122TGFBR10.24894515
123EEF2K0.24786138
124MET0.24405137
125WNK30.24388165
126DAPK10.24094941
127ERBB40.24005475
128STK30.22993990
129MAPK110.21840523
130FLT30.21318918
131DYRK1B0.21096951
132AKT10.19552512

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.02313450
2Mismatch repair_Homo sapiens_hsa034304.38472173
3Ribosome_Homo sapiens_hsa030104.35061151
4Spliceosome_Homo sapiens_hsa030403.50975885
5RNA polymerase_Homo sapiens_hsa030203.44787605
6Base excision repair_Homo sapiens_hsa034103.44731664
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.37055580
8* Homologous recombination_Homo sapiens_hsa034403.32174374
9Proteasome_Homo sapiens_hsa030503.17896912
10RNA transport_Homo sapiens_hsa030132.94053357
11Nucleotide excision repair_Homo sapiens_hsa034202.93626737
12Cell cycle_Homo sapiens_hsa041102.64940386
13One carbon pool by folate_Homo sapiens_hsa006702.53073535
14Pyrimidine metabolism_Homo sapiens_hsa002402.50289655
15* Fanconi anemia pathway_Homo sapiens_hsa034602.46371294
16Non-homologous end-joining_Homo sapiens_hsa034502.19387992
17Basal transcription factors_Homo sapiens_hsa030221.97278675
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.95138949
19mRNA surveillance pathway_Homo sapiens_hsa030151.75828779
20RNA degradation_Homo sapiens_hsa030181.73975244
21p53 signaling pathway_Homo sapiens_hsa041151.48739011
22Systemic lupus erythematosus_Homo sapiens_hsa053221.24678777
23Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.23156018
24Purine metabolism_Homo sapiens_hsa002301.22608027
252-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.18634605
26Sulfur relay system_Homo sapiens_hsa041221.16337473
27Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.15272465
28Pyruvate metabolism_Homo sapiens_hsa006201.14685040
29Epstein-Barr virus infection_Homo sapiens_hsa051691.12338949
30Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.05564219
31Protein export_Homo sapiens_hsa030601.04904285
32Oocyte meiosis_Homo sapiens_hsa041141.02476039
33Folate biosynthesis_Homo sapiens_hsa007900.98490880
34Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.93756436
35Steroid biosynthesis_Homo sapiens_hsa001000.92419436
36Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.87806712
37Huntingtons disease_Homo sapiens_hsa050160.85012000
38Herpes simplex infection_Homo sapiens_hsa051680.84814387
39Basal cell carcinoma_Homo sapiens_hsa052170.77410167
40Viral carcinogenesis_Homo sapiens_hsa052030.76127242
41Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.73164947
42Parkinsons disease_Homo sapiens_hsa050120.70500819
43HTLV-I infection_Homo sapiens_hsa051660.68418304
44Antigen processing and presentation_Homo sapiens_hsa046120.66534011
45Propanoate metabolism_Homo sapiens_hsa006400.65829700
46Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.64737672
47Oxidative phosphorylation_Homo sapiens_hsa001900.64020678
48MicroRNAs in cancer_Homo sapiens_hsa052060.62201986
49Pentose phosphate pathway_Homo sapiens_hsa000300.61736333
50Hedgehog signaling pathway_Homo sapiens_hsa043400.56370183
51Fatty acid elongation_Homo sapiens_hsa000620.56362608
52Cardiac muscle contraction_Homo sapiens_hsa042600.55740148
53Bladder cancer_Homo sapiens_hsa052190.54139182
54Hippo signaling pathway_Homo sapiens_hsa043900.53971918
55Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.53948284
56Alcoholism_Homo sapiens_hsa050340.51615429
57Biosynthesis of amino acids_Homo sapiens_hsa012300.51475859
58Cysteine and methionine metabolism_Homo sapiens_hsa002700.50812412
59Legionellosis_Homo sapiens_hsa051340.49448527
60Thyroid cancer_Homo sapiens_hsa052160.49225353
61Lysine degradation_Homo sapiens_hsa003100.49153998
62Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47274771
63Glutathione metabolism_Homo sapiens_hsa004800.45856123
64Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.45026832
65Drug metabolism - other enzymes_Homo sapiens_hsa009830.44292278
66Cyanoamino acid metabolism_Homo sapiens_hsa004600.43952591
67Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.43516152
68Transcriptional misregulation in cancer_Homo sapiens_hsa052020.43084620
69Notch signaling pathway_Homo sapiens_hsa043300.37934041
70Apoptosis_Homo sapiens_hsa042100.36646573
71Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.36613346
72Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.35673955
73Selenocompound metabolism_Homo sapiens_hsa004500.35074306
74TGF-beta signaling pathway_Homo sapiens_hsa043500.34565492
75Small cell lung cancer_Homo sapiens_hsa052220.33408770
76Vitamin digestion and absorption_Homo sapiens_hsa049770.31959986
77Vitamin B6 metabolism_Homo sapiens_hsa007500.31381725
78Wnt signaling pathway_Homo sapiens_hsa043100.30965331
79Primary immunodeficiency_Homo sapiens_hsa053400.30762346
80Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.30174601
81Hepatitis B_Homo sapiens_hsa051610.28247173
82Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.27649602
83Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.26174724
84Arachidonic acid metabolism_Homo sapiens_hsa005900.25634759
85Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.24060290
86NF-kappa B signaling pathway_Homo sapiens_hsa040640.23915072
87Pathways in cancer_Homo sapiens_hsa052000.22507874
88Sulfur metabolism_Homo sapiens_hsa009200.22481480
89Colorectal cancer_Homo sapiens_hsa052100.21248081
90Alzheimers disease_Homo sapiens_hsa050100.21173820
91Prostate cancer_Homo sapiens_hsa052150.21008529
92NOD-like receptor signaling pathway_Homo sapiens_hsa046210.20957843
93Shigellosis_Homo sapiens_hsa051310.19644523
94Measles_Homo sapiens_hsa051620.18945958
95Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.18925490
96Galactose metabolism_Homo sapiens_hsa000520.18671954
97Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.18076715
98Metabolic pathways_Homo sapiens_hsa011000.17469108
99Melanoma_Homo sapiens_hsa052180.16805543
100Chronic myeloid leukemia_Homo sapiens_hsa052200.16675387
101N-Glycan biosynthesis_Homo sapiens_hsa005100.16485546
102Acute myeloid leukemia_Homo sapiens_hsa052210.16289819
103Arginine biosynthesis_Homo sapiens_hsa002200.15713321
104Fructose and mannose metabolism_Homo sapiens_hsa000510.14272060
105Tyrosine metabolism_Homo sapiens_hsa003500.14149607
106Fatty acid metabolism_Homo sapiens_hsa012120.13318552
107Asthma_Homo sapiens_hsa053100.13048162
108Hematopoietic cell lineage_Homo sapiens_hsa046400.12647192
109HIF-1 signaling pathway_Homo sapiens_hsa040660.11441092
110Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.10218590
111Arginine and proline metabolism_Homo sapiens_hsa003300.10183158
112Peroxisome_Homo sapiens_hsa041460.09541493
113RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.09307779
114Influenza A_Homo sapiens_hsa051640.08339969
115Carbon metabolism_Homo sapiens_hsa012000.08151921
116Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.07887426
117Fatty acid degradation_Homo sapiens_hsa000710.06012186
118Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.05199322
119Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.05126382
120Regulation of autophagy_Homo sapiens_hsa041400.04907405
121Central carbon metabolism in cancer_Homo sapiens_hsa052300.04516377
122Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.04328130
123PI3K-Akt signaling pathway_Homo sapiens_hsa041510.03949134
124Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.03800489
125Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.03527778
126Pentose and glucuronate interconversions_Homo sapiens_hsa000400.01649382

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