EIF1B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1chaperone-mediated protein transport (GO:0072321)5.23084048
2mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.09443467
3energy coupled proton transport, down electrochemical gradient (GO:0015985)5.03480557
4ATP synthesis coupled proton transport (GO:0015986)5.03480557
5pyrimidine nucleobase catabolic process (GO:0006208)5.03210448
6neuron cell-cell adhesion (GO:0007158)4.77951655
7synaptic vesicle exocytosis (GO:0016079)4.61662544
8mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.55477635
9protein localization to synapse (GO:0035418)4.08551605
10negative regulation of microtubule polymerization (GO:0031115)3.99717862
11positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.96254423
12nucleobase catabolic process (GO:0046113)3.96131907
13neuronal action potential propagation (GO:0019227)3.92144628
14respiratory electron transport chain (GO:0022904)3.88786424
15electron transport chain (GO:0022900)3.80387907
16protein neddylation (GO:0045116)3.68343292
17response to pheromone (GO:0019236)3.68295672
18behavioral response to nicotine (GO:0035095)3.66425272
19vocalization behavior (GO:0071625)3.55181134
20regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.50669834
21nonmotile primary cilium assembly (GO:0035058)3.46126716
22neuron recognition (GO:0008038)3.41919943
23positive regulation of mitochondrial fission (GO:0090141)3.38517101
24DNA double-strand break processing (GO:0000729)3.37860596
25regulation of short-term neuronal synaptic plasticity (GO:0048172)3.36805278
26regulation of synaptic vesicle exocytosis (GO:2000300)3.36698951
27regulation of feeding behavior (GO:0060259)3.34543196
28regulation of synaptic vesicle transport (GO:1902803)3.21195531
29cell migration in hindbrain (GO:0021535)3.19949132
30protein complex biogenesis (GO:0070271)3.19946402
31glutamate secretion (GO:0014047)3.13412144
32positive regulation of amino acid transport (GO:0051957)3.12583753
33short-term memory (GO:0007614)3.12183281
34synaptic vesicle maturation (GO:0016188)3.07923799
35sequestering of actin monomers (GO:0042989)3.04537079
36energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.02850545
37ATP hydrolysis coupled proton transport (GO:0015991)3.02850545
38protein deneddylation (GO:0000338)3.02528168
39DNA damage response, detection of DNA damage (GO:0042769)3.02505801
40NADH dehydrogenase complex assembly (GO:0010257)3.01180224
41mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.01180224
42mitochondrial respiratory chain complex I assembly (GO:0032981)3.01180224
43positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.98223379
44organelle disassembly (GO:1903008)2.97792476
45regulation of glutamate receptor signaling pathway (GO:1900449)2.96721629
46positive regulation of synapse assembly (GO:0051965)2.96314714
47gamma-aminobutyric acid signaling pathway (GO:0007214)2.96255202
48glutamate receptor signaling pathway (GO:0007215)2.95760592
49hydrogen ion transmembrane transport (GO:1902600)2.92759048
50postsynaptic membrane organization (GO:0001941)2.92687387
51presynaptic membrane assembly (GO:0097105)2.91196459
52water-soluble vitamin biosynthetic process (GO:0042364)2.90583439
53GTP biosynthetic process (GO:0006183)2.90535443
54axonal fasciculation (GO:0007413)2.90454394
55negative regulation of synaptic transmission, GABAergic (GO:0032229)2.89597265
56establishment of mitochondrion localization (GO:0051654)2.89305096
57positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.88850328
58presynaptic membrane organization (GO:0097090)2.87708595
59cullin deneddylation (GO:0010388)2.87596058
60proteasome assembly (GO:0043248)2.87521466
61ionotropic glutamate receptor signaling pathway (GO:0035235)2.86569537
62platelet dense granule organization (GO:0060155)2.86305476
63mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.86285238
64epithelial cilium movement (GO:0003351)2.86094677
65exploration behavior (GO:0035640)2.85519912
66intraciliary transport (GO:0042073)2.84590623
67gamma-aminobutyric acid transport (GO:0015812)2.84587261
68synaptic vesicle transport (GO:0048489)2.83878402
69establishment of synaptic vesicle localization (GO:0097480)2.83878402
70protein-cofactor linkage (GO:0018065)2.83271443
71regulation of cilium movement (GO:0003352)2.83150456
72calcium-mediated signaling using intracellular calcium source (GO:0035584)2.83044069
73mitochondrial respiratory chain complex assembly (GO:0033108)2.82909434
74neural tube formation (GO:0001841)2.82368114
75mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.82066897
76positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.82066897
77negative regulation of transcription regulatory region DNA binding (GO:2000678)2.81810957
78substantia nigra development (GO:0021762)2.81167339
79synaptic transmission, glutamatergic (GO:0035249)2.80469440
80neuron-neuron synaptic transmission (GO:0007270)2.78378189
81regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.78029729
82regulation of vesicle fusion (GO:0031338)2.77527060
83synaptic vesicle endocytosis (GO:0048488)2.76977634
84regulation of neuronal synaptic plasticity (GO:0048168)2.76975375
85neurotransmitter secretion (GO:0007269)2.76409943
86axon ensheathment in central nervous system (GO:0032291)2.76337119
87central nervous system myelination (GO:0022010)2.76337119
88layer formation in cerebral cortex (GO:0021819)2.74964410
89somite development (GO:0061053)2.73383783
90respiratory chain complex IV assembly (GO:0008535)2.73038649
91piRNA metabolic process (GO:0034587)2.72982117
92purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.72480822
93regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.71427587
94locomotory exploration behavior (GO:0035641)2.69690283
95transmission of nerve impulse (GO:0019226)2.69378677
96nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.68080072
97ATP biosynthetic process (GO:0006754)2.67322358
98synaptic transmission, cholinergic (GO:0007271)2.64309635
99regulation of long-term neuronal synaptic plasticity (GO:0048169)2.64033455
100ribonucleoprotein complex disassembly (GO:0032988)2.63592516
101regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.63140857
102purine nucleoside triphosphate biosynthetic process (GO:0009145)2.63098839
103righting reflex (GO:0060013)2.62471288
104regulation of dopamine metabolic process (GO:0042053)2.61795548
105regulation of catecholamine metabolic process (GO:0042069)2.61795548
106positive regulation of synaptic transmission, GABAergic (GO:0032230)2.60359768
107protein localization to cilium (GO:0061512)2.59727651
108negative regulation of membrane potential (GO:0045837)2.59482867
109positive regulation of membrane potential (GO:0045838)2.59343136
110inner mitochondrial membrane organization (GO:0007007)2.59112575
111exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.58899982
112negative regulation of telomere maintenance (GO:0032205)2.58605580
113limb bud formation (GO:0060174)2.58442609
114regulation of glutamate secretion (GO:0014048)2.57847438
115innervation (GO:0060384)2.57416170
116detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.57190456
117detection of temperature stimulus involved in sensory perception (GO:0050961)2.57190456
118pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.56895736
119negative regulation of heart rate (GO:0010459)2.56618027
120proton transport (GO:0015992)2.55668130
121regulation of neurotransmitter secretion (GO:0046928)2.54537314
122neurofilament cytoskeleton organization (GO:0060052)2.52980825
123adult walking behavior (GO:0007628)2.52853205
124centriole replication (GO:0007099)2.52374527
125anterograde synaptic vesicle transport (GO:0048490)2.51480937
126regulation of synapse structural plasticity (GO:0051823)2.51169347
127single strand break repair (GO:0000012)2.50687403
128hydrogen transport (GO:0006818)2.50292805
129transferrin transport (GO:0033572)2.49892824
130G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.49870939
131regulation of respiratory system process (GO:0044065)2.49794210
132neurotransmitter transport (GO:0006836)2.49620007
133protein polyglutamylation (GO:0018095)2.49303537
134retinal ganglion cell axon guidance (GO:0031290)2.49186094
135regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.48995597
136neurotransmitter-gated ion channel clustering (GO:0072578)2.48390578
137auditory behavior (GO:0031223)2.47636564
138establishment of protein localization to mitochondrial membrane (GO:0090151)2.46309451
139establishment of vesicle localization (GO:0051650)2.46130524
140epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.44955894
141glycosphingolipid biosynthetic process (GO:0006688)2.44718261
142tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.43726683
143RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.43726683
144cilium morphogenesis (GO:0060271)2.43640742
145guanosine-containing compound biosynthetic process (GO:1901070)2.42722899
146intracellular protein transmembrane import (GO:0044743)2.42627909
147negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.42026465
148regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.41318169
149regulation of mitotic spindle checkpoint (GO:1903504)2.41318169
150positive regulation of meiosis (GO:0045836)2.41272046
151regulation of development, heterochronic (GO:0040034)2.41117447
152membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.40162574
153regulation of meiosis I (GO:0060631)2.39346575
154regulation of action potential (GO:0098900)2.37750955
155negative regulation of appetite (GO:0032099)2.36720044
156negative regulation of response to food (GO:0032096)2.36720044
157anterograde axon cargo transport (GO:0008089)2.36518351
158cerebral cortex radially oriented cell migration (GO:0021799)2.35566907

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.00493449
2GBX2_23144817_ChIP-Seq_PC3_Human3.11436832
3JARID2_20064375_ChIP-Seq_MESCs_Mouse2.90795724
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.71577157
5EZH2_27304074_Chip-Seq_ESCs_Mouse2.63934374
6NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.57886759
7REST_21632747_ChIP-Seq_MESCs_Mouse2.43947815
8JARID2_20075857_ChIP-Seq_MESCs_Mouse2.43886440
9SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.40778290
10TAF15_26573619_Chip-Seq_HEK293_Human2.39828104
11BMI1_23680149_ChIP-Seq_NPCS_Mouse2.23310542
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.21995878
13RNF2_18974828_ChIP-Seq_MESCs_Mouse2.21995878
14SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.21275316
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.17760535
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.12827485
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.11997245
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.09526547
19REST_18959480_ChIP-ChIP_MESCs_Mouse2.06811224
20CBX2_27304074_Chip-Seq_ESCs_Mouse2.04226244
21TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.03914462
22SUZ12_27294783_Chip-Seq_ESCs_Mouse2.03876884
23SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.03658522
24IGF1R_20145208_ChIP-Seq_DFB_Human2.03130438
25HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.01938046
26CTBP2_25329375_ChIP-Seq_LNCAP_Human2.00624126
27MTF2_20144788_ChIP-Seq_MESCs_Mouse2.00218662
28VDR_22108803_ChIP-Seq_LS180_Human1.93826104
29RNF2_27304074_Chip-Seq_NSC_Mouse1.89159994
30RNF2_27304074_Chip-Seq_ESCs_Mouse1.87111935
31FLI1_27457419_Chip-Seq_LIVER_Mouse1.86213515
32PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.82041169
33ZFP57_27257070_Chip-Seq_ESCs_Mouse1.81570364
34CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.80620495
35CTBP1_25329375_ChIP-Seq_LNCAP_Human1.79693707
36SALL1_21062744_ChIP-ChIP_HESCs_Human1.76627698
37SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.72098851
38ELK1_19687146_ChIP-ChIP_HELA_Human1.69609381
39IRF1_19129219_ChIP-ChIP_H3396_Human1.69014012
40CREB1_15753290_ChIP-ChIP_HEK293T_Human1.59104994
41P300_19829295_ChIP-Seq_ESCs_Human1.54893481
42HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.54135223
43* VDR_23849224_ChIP-Seq_CD4+_Human1.48662750
44HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.48276447
45MYC_18940864_ChIP-ChIP_HL60_Human1.44203681
46RARB_27405468_Chip-Seq_BRAIN_Mouse1.43957576
47ZNF274_21170338_ChIP-Seq_K562_Hela1.43887296
48FUS_26573619_Chip-Seq_HEK293_Human1.43838491
49IKZF1_21737484_ChIP-ChIP_HCT116_Human1.43305575
50CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.43236430
51PCGF2_27294783_Chip-Seq_ESCs_Mouse1.41393660
52GABP_17652178_ChIP-ChIP_JURKAT_Human1.41194647
53TP53_22573176_ChIP-Seq_HFKS_Human1.38607919
54CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.38426293
55RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.37534304
56AR_21572438_ChIP-Seq_LNCaP_Human1.36847896
57MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.34862072
58PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.33736280
59TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.33389471
60POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.33389471
61POU3F2_20337985_ChIP-ChIP_501MEL_Human1.29482095
62ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.29428248
63CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.29259169
64TOP2B_26459242_ChIP-Seq_MCF-7_Human1.28621417
65CBP_20019798_ChIP-Seq_JUKART_Human1.26371440
66IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.26371440
67KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.25779296
68* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25318190
69FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.25228522
70GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25089475
71PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.22553328
72SMAD4_21799915_ChIP-Seq_A2780_Human1.22062540
73JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.20669733
74EZH2_27294783_Chip-Seq_NPCs_Mouse1.20647975
75MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.19425867
76* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.19025259
77KLF5_20875108_ChIP-Seq_MESCs_Mouse1.16562400
78SUZ12_27294783_Chip-Seq_NPCs_Mouse1.15951773
79BCAT_22108803_ChIP-Seq_LS180_Human1.15555210
80SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.13751269
81AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.13747891
82HTT_18923047_ChIP-ChIP_STHdh_Human1.13725605
83CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13318798
84* SOX2_19829295_ChIP-Seq_ESCs_Human1.13176960
85* NANOG_19829295_ChIP-Seq_ESCs_Human1.13176960
86RBPJ_22232070_ChIP-Seq_NCS_Mouse1.12633495
87EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.12465202
88PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.12254048
89NR3C1_23031785_ChIP-Seq_PC12_Mouse1.11997000
90PIAS1_25552417_ChIP-Seq_VCAP_Human1.11458278
91E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.10437794
92GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.09276586
93NFE2_27457419_Chip-Seq_LIVER_Mouse1.09125916
94ER_23166858_ChIP-Seq_MCF-7_Human1.08706916
95SOX2_16153702_ChIP-ChIP_HESCs_Human1.07454310
96SMAD3_21741376_ChIP-Seq_EPCs_Human1.05908441
97FOXP3_21729870_ChIP-Seq_TREG_Human1.05507686
98EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.05426392
99NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.05281398
100RING1B_27294783_Chip-Seq_ESCs_Mouse1.04600931
101RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.03444906
102P53_22387025_ChIP-Seq_ESCs_Mouse1.03225986
103THAP11_20581084_ChIP-Seq_MESCs_Mouse1.02683224
104DROSHA_22980978_ChIP-Seq_HELA_Human1.02296022
105FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.01960572
106UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.01859335
107SRF_21415370_ChIP-Seq_HL-1_Mouse1.01132332
108JUN_21703547_ChIP-Seq_K562_Human1.00924003
109GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.00696733
110RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.99864948
111MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.99221159
112PCGF2_27294783_Chip-Seq_NPCs_Mouse0.99107097
113PRDM14_20953172_ChIP-Seq_ESCs_Human0.98765039
114EST1_17652178_ChIP-ChIP_JURKAT_Human0.97899976
115TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.97407288
116ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.96963424
117KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.96812613
118OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.96769445
119AR_25329375_ChIP-Seq_VCAP_Human0.96682851
120NR3C1_21868756_ChIP-Seq_MCF10A_Human0.95758948
121REST_19997604_ChIP-ChIP_NEURONS_Mouse0.95460295
122* SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.95307530
123CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.94510392
124CRX_20693478_ChIP-Seq_RETINA_Mouse0.94046839
125STAT3_23295773_ChIP-Seq_U87_Human0.93911007
126MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.92739756
127TCF4_23295773_ChIP-Seq_U87_Human0.92548438
128PADI4_21655091_ChIP-ChIP_MCF-7_Human0.92336899
129* ETS1_20019798_ChIP-Seq_JURKAT_Human0.92060329
130NCOR_22424771_ChIP-Seq_293T_Human0.91603446
131EWS_26573619_Chip-Seq_HEK293_Human0.90478574
132P53_22127205_ChIP-Seq_FIBROBLAST_Human0.90137121
133TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89390982
134SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.88744748
135ERG_21242973_ChIP-ChIP_JURKAT_Human0.87662226
136NANOG_18555785_Chip-Seq_ESCs_Mouse0.86552026
137RUNX2_22187159_ChIP-Seq_PCA_Human0.83346914
138POU5F1_16153702_ChIP-ChIP_HESCs_Human0.83309576
139TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.82950446
140TAL1_26923725_Chip-Seq_HPCs_Mouse0.82812746
141SOX9_26525672_Chip-Seq_HEART_Mouse0.81809691
142CTCF_18555785_ChIP-Seq_MESCs_Mouse0.81628345
143CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.81621843

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.63406787
2MP0004859_abnormal_synaptic_plasticity3.78196338
3MP0004270_analgesia3.29765822
4MP0001968_abnormal_touch/_nociception3.07768136
5MP0003635_abnormal_synaptic_transmissio2.99280104
6MP0001529_abnormal_vocalization2.95878511
7MP0006276_abnormal_autonomic_nervous2.83507588
8MP0002736_abnormal_nociception_after2.77788392
9MP0002735_abnormal_chemical_nociception2.73280338
10MP0002734_abnormal_mechanical_nocicepti2.72296593
11MP0005423_abnormal_somatic_nervous2.62738890
12MP0009745_abnormal_behavioral_response2.48725447
13MP0002063_abnormal_learning/memory/cond2.44443185
14MP0002064_seizures2.43431117
15MP0002272_abnormal_nervous_system2.36989986
16MP0002572_abnormal_emotion/affect_behav2.31303978
17MP0009046_muscle_twitch2.28856915
18MP0002733_abnormal_thermal_nociception2.27043864
19MP0001905_abnormal_dopamine_level2.19218117
20MP0001984_abnormal_olfaction2.15907310
21MP0000778_abnormal_nervous_system2.14937444
22MP0001970_abnormal_pain_threshold2.13363472
23MP0001486_abnormal_startle_reflex2.05532737
24MP0002184_abnormal_innervation2.02296775
25MP0001440_abnormal_grooming_behavior1.90237141
26MP0002067_abnormal_sensory_capabilities1.86625207
27MP0005646_abnormal_pituitary_gland1.82488995
28MP0002638_abnormal_pupillary_reflex1.75794703
29MP0003122_maternal_imprinting1.72348845
30MP0004142_abnormal_muscle_tone1.69892562
31MP0005645_abnormal_hypothalamus_physiol1.69356023
32MP0002557_abnormal_social/conspecific_i1.62581350
33MP0003011_delayed_dark_adaptation1.61356243
34MP0001986_abnormal_taste_sensitivity1.58048940
35MP0000955_abnormal_spinal_cord1.57788005
36MP0001188_hyperpigmentation1.55289695
37MP0004924_abnormal_behavior1.54286282
38MP0005386_behavior/neurological_phenoty1.54286282
39MP0006292_abnormal_olfactory_placode1.53595646
40MP0008877_abnormal_DNA_methylation1.50448004
41MP0005084_abnormal_gallbladder_morpholo1.50287003
42MP0008058_abnormal_DNA_repair1.46161631
43MP0004811_abnormal_neuron_physiology1.44141512
44MP0002882_abnormal_neuron_morphology1.44002210
45MP0009379_abnormal_foot_pigmentation1.41675199
46MP0005409_darkened_coat_color1.34782132
47MP0008569_lethality_at_weaning1.33743183
48MP0004133_heterotaxia1.32031709
49MP0003646_muscle_fatigue1.31852067
50MP0003329_amyloid_beta_deposits1.31700229
51MP0004147_increased_porphyrin_level1.30813451
52MP0001501_abnormal_sleep_pattern1.30319991
53MP0002837_dystrophic_cardiac_calcinosis1.29068465
54MP0005551_abnormal_eye_electrophysiolog1.28516679
55MP0002066_abnormal_motor_capabilities/c1.26468948
56MP0000631_abnormal_neuroendocrine_gland1.25840324
57MP0002653_abnormal_ependyma_morphology1.23417459
58MP0006072_abnormal_retinal_apoptosis1.23042113
59MP0001502_abnormal_circadian_rhythm1.22594648
60MP0010386_abnormal_urinary_bladder1.21684896
61MP0004742_abnormal_vestibular_system1.21464489
62MP0002751_abnormal_autonomic_nervous1.20556560
63MP0002752_abnormal_somatic_nervous1.19879655
64MP0003890_abnormal_embryonic-extraembry1.15450204
65MP0005410_abnormal_fertilization1.10319486
66MP0002102_abnormal_ear_morphology1.10167184
67MP0002152_abnormal_brain_morphology1.09692293
68MP0002909_abnormal_adrenal_gland1.09259351
69MP0004858_abnormal_nervous_system1.09126662
70MP0004145_abnormal_muscle_electrophysio1.08446885
71MP0000751_myopathy1.07569353
72MP0003186_abnormal_redox_activity1.05652879
73MP0005187_abnormal_penis_morphology1.04222571
74MP0002229_neurodegeneration1.03020102
75MP0003567_abnormal_fetal_cardiomyocyte1.02034111
76MP0001963_abnormal_hearing_physiology1.00460760
77MP0002822_catalepsy0.99479217
78MP0002090_abnormal_vision0.97498323
79MP0005379_endocrine/exocrine_gland_phen0.97007186
80MP0005394_taste/olfaction_phenotype0.95371642
81MP0005499_abnormal_olfactory_system0.95371642
82MP0000920_abnormal_myelination0.92701057
83MP0002163_abnormal_gland_morphology0.92598267
84MP0000015_abnormal_ear_pigmentation0.92274527
85MP0003879_abnormal_hair_cell0.92265597
86MP0000026_abnormal_inner_ear0.91620433
87MP0008789_abnormal_olfactory_epithelium0.91133864
88MP0001485_abnormal_pinna_reflex0.90824725
89MP0002234_abnormal_pharynx_morphology0.89900525
90MP0003221_abnormal_cardiomyocyte_apopto0.88880817
91MP0004885_abnormal_endolymph0.88647538
92MP0003787_abnormal_imprinting0.88516955
93MP0003634_abnormal_glial_cell0.88147400
94MP0003195_calcinosis0.87644780
95MP0004085_abnormal_heartbeat0.87567479
96MP0001293_anophthalmia0.86530535
97MP0008872_abnormal_physiological_respon0.85980179
98MP0003698_abnormal_male_reproductive0.85784270
99MP0002277_abnormal_respiratory_mucosa0.83812635
100MP0003718_maternal_effect0.82912993
101MP0005253_abnormal_eye_physiology0.82733143
102MP0000049_abnormal_middle_ear0.82570562
103MP0002210_abnormal_sex_determination0.80847619
104MP0001764_abnormal_homeostasis0.80114401
105MP0005167_abnormal_blood-brain_barrier0.79950589
106MP0003121_genomic_imprinting0.78310923
107MP0003315_abnormal_perineum_morphology0.77511020
108MP0003631_nervous_system_phenotype0.76353973
109MP0008995_early_reproductive_senescence0.76105709
110MP0003633_abnormal_nervous_system0.75682486
111MP0003861_abnormal_nervous_system0.75219406
112MP0003119_abnormal_digestive_system0.74116750
113MP0000647_abnormal_sebaceous_gland0.73894337
114MP0000013_abnormal_adipose_tissue0.73807182
115MP0004215_abnormal_myocardial_fiber0.72465802
116MP0003136_yellow_coat_color0.71420080
117MP0003137_abnormal_impulse_conducting0.70951384
118MP0002069_abnormal_eating/drinking_beha0.69994777
119MP0003938_abnormal_ear_development0.67837305
120MP0002938_white_spotting0.64582044
121MP0006036_abnormal_mitochondrial_physio0.64040152
122MP0001929_abnormal_gametogenesis0.63411819
123MP0006035_abnormal_mitochondrial_morpho0.63101813
124MP0000372_irregular_coat_pigmentation0.60851915

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.44563444
2Acute necrotizing encephalopathy (HP:0006965)4.70579409
3Focal motor seizures (HP:0011153)4.40134083
4Abnormal mitochondria in muscle tissue (HP:0008316)4.27797985
5Mitochondrial inheritance (HP:0001427)4.00673300
6Progressive macrocephaly (HP:0004481)3.94876296
7Atonic seizures (HP:0010819)3.66165209
8Acute encephalopathy (HP:0006846)3.58207250
9Epileptic encephalopathy (HP:0200134)3.46681226
10Pheochromocytoma (HP:0002666)3.27270166
11Increased hepatocellular lipid droplets (HP:0006565)3.26700998
12Increased CSF lactate (HP:0002490)3.22963542
13Neuroendocrine neoplasm (HP:0100634)3.21466796
14Focal seizures (HP:0007359)3.15795264
15Hepatocellular necrosis (HP:0001404)3.14700695
16Methylmalonic acidemia (HP:0002912)3.09616435
17Abnormality of the labia minora (HP:0012880)3.07940222
18Visual hallucinations (HP:0002367)3.01023642
19Febrile seizures (HP:0002373)2.92409575
20Abnormal hair whorl (HP:0010721)2.91905142
21Renal Fanconi syndrome (HP:0001994)2.90253880
22True hermaphroditism (HP:0010459)2.90115236
23Gait imbalance (HP:0002141)2.90045581
24Limb dystonia (HP:0002451)2.84522512
25Medial flaring of the eyebrow (HP:0010747)2.82982721
26Abnormality of glycolysis (HP:0004366)2.82409762
27Increased serum pyruvate (HP:0003542)2.82409762
28Lipid accumulation in hepatocytes (HP:0006561)2.81959725
29Pancreatic fibrosis (HP:0100732)2.78425409
30Progressive cerebellar ataxia (HP:0002073)2.78424237
31Retinal dysplasia (HP:0007973)2.77616714
32Pancreatic cysts (HP:0001737)2.76580572
33Optic disc pallor (HP:0000543)2.72896254
34Abnormality of midbrain morphology (HP:0002418)2.66790641
35Molar tooth sign on MRI (HP:0002419)2.66790641
36Polyphagia (HP:0002591)2.64178576
37Absence seizures (HP:0002121)2.62264857
38Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.58123789
39Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.57879796
40Congenital primary aphakia (HP:0007707)2.55035492
41Increased intramyocellular lipid droplets (HP:0012240)2.50177751
42Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.49398651
43Decreased activity of mitochondrial respiratory chain (HP:0008972)2.49398651
44Hyperglycinemia (HP:0002154)2.47749389
45Dialeptic seizures (HP:0011146)2.44250357
46Leukodystrophy (HP:0002415)2.41368254
47Methylmalonic aciduria (HP:0012120)2.40901674
48Nephrogenic diabetes insipidus (HP:0009806)2.40089270
49Poor suck (HP:0002033)2.37496494
50Supranuclear gaze palsy (HP:0000605)2.37368379
51Amblyopia (HP:0000646)2.36285377
52Ankle clonus (HP:0011448)2.36256990
53Hypothermia (HP:0002045)2.34946671
54Nephronophthisis (HP:0000090)2.34135049
55Anxiety (HP:0000739)2.33041784
56Cerebral edema (HP:0002181)2.31442799
57Esotropia (HP:0000565)2.30953181
58Genital tract atresia (HP:0001827)2.30460649
59Broad-based gait (HP:0002136)2.29752207
60Vaginal atresia (HP:0000148)2.29127061
61Delusions (HP:0000746)2.27452364
62Dynein arm defect of respiratory motile cilia (HP:0012255)2.25376586
63Absent/shortened dynein arms (HP:0200106)2.25376586
64Progressive inability to walk (HP:0002505)2.24637402
65Abnormal eating behavior (HP:0100738)2.24626886
66Degeneration of the lateral corticospinal tracts (HP:0002314)2.23566698
67Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.23566698
68Generalized tonic-clonic seizures (HP:0002069)2.22081266
69Hyperventilation (HP:0002883)2.21658429
70Exercise intolerance (HP:0003546)2.21638001
71Abnormal respiratory motile cilium morphology (HP:0005938)2.18858348
72Abnormal respiratory epithelium morphology (HP:0012253)2.18858348
73Aplasia/Hypoplasia of the brainstem (HP:0007362)2.16295863
74Hypoplasia of the brainstem (HP:0002365)2.16295863
75Hepatic necrosis (HP:0002605)2.15562213
76Drooling (HP:0002307)2.13088121
77Lactic acidosis (HP:0003128)2.11013882
78Neurofibrillary tangles (HP:0002185)2.10270303
79Respiratory failure (HP:0002878)2.08784056
80Poor coordination (HP:0002370)2.07726196
81Abnormality of the corticospinal tract (HP:0002492)2.07589055
82Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.07514665
83Cortical dysplasia (HP:0002539)2.05113027
84Lissencephaly (HP:0001339)2.04944248
85Hemiparesis (HP:0001269)2.04649921
86Agitation (HP:0000713)2.04308972
87Intestinal atresia (HP:0011100)2.02238137
88Specific learning disability (HP:0001328)2.02153620
89Pachygyria (HP:0001302)2.01569254
90Amyotrophic lateral sclerosis (HP:0007354)2.00004479
91Atrophy/Degeneration involving motor neurons (HP:0007373)1.99724607
923-Methylglutaconic aciduria (HP:0003535)1.99246794
93Truncal ataxia (HP:0002078)1.98818487
94Abnormal respiratory motile cilium physiology (HP:0012261)1.98409097
95Epileptiform EEG discharges (HP:0011182)1.98382931
96Failure to thrive in infancy (HP:0001531)1.95776262
97EEG with generalized epileptiform discharges (HP:0011198)1.94662141
98Abnormal ciliary motility (HP:0012262)1.93765841
99Spastic gait (HP:0002064)1.93566023
100Optic nerve hypoplasia (HP:0000609)1.93205974
101Excessive salivation (HP:0003781)1.92912459
102Increased muscle lipid content (HP:0009058)1.92764509
103Increased serum lactate (HP:0002151)1.92339476
104Abnormality of the renal medulla (HP:0100957)1.91408984
105Inability to walk (HP:0002540)1.90182257
106Abolished electroretinogram (ERG) (HP:0000550)1.88325415
107Exertional dyspnea (HP:0002875)1.87165297
108Unsteady gait (HP:0002317)1.86082584
109Termporal pattern (HP:0011008)1.86030788
110Insidious onset (HP:0003587)1.86030788
111Left ventricular hypertrophy (HP:0001712)1.85573049
112Mutism (HP:0002300)1.85534765
113Peripheral hypomyelination (HP:0007182)1.85243694
114Respiratory difficulties (HP:0002880)1.84465906
115Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.84390429
116Colon cancer (HP:0003003)1.84061104
117Renal cortical cysts (HP:0000803)1.83715511
118Postaxial hand polydactyly (HP:0001162)1.83658221
119Dysmetria (HP:0001310)1.83131937
120Emotional lability (HP:0000712)1.82672385
121Abnormality of renal resorption (HP:0011038)1.82325014
122Hypsarrhythmia (HP:0002521)1.82277864
123Broad foot (HP:0001769)1.82277069
124Neoplasm of the peripheral nervous system (HP:0100007)1.82204827
125Anencephaly (HP:0002323)1.81343958
126Action tremor (HP:0002345)1.80837774
127Severe visual impairment (HP:0001141)1.80632154
128Decreased testicular size (HP:0008734)1.79034721
129Abnormality of urine glucose concentration (HP:0011016)1.78868062
130Glycosuria (HP:0003076)1.78868062
131X-linked dominant inheritance (HP:0001423)1.78749027
132Septo-optic dysplasia (HP:0100842)1.78450465
133Abnormality of the heme biosynthetic pathway (HP:0010472)1.78362314
134Degeneration of anterior horn cells (HP:0002398)1.77927815
135Abnormality of the anterior horn cell (HP:0006802)1.77927815
136Type II lissencephaly (HP:0007260)1.76621337
137Spastic tetraplegia (HP:0002510)1.75944551
138Sclerocornea (HP:0000647)1.75525214
139Muscular hypotonia of the trunk (HP:0008936)1.75135712
140Male pseudohermaphroditism (HP:0000037)1.73732197
141Depression (HP:0000716)1.72848052
142Hyperalaninemia (HP:0003348)1.72711165
143Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.72711165
144Abnormality of alanine metabolism (HP:0010916)1.72711165
145Narrow forehead (HP:0000341)1.70691182
146Abnormality of the renal cortex (HP:0011035)1.69243215

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK13.31513599
2MAP3K123.21770511
3CASK2.87302825
4TRIM282.84740202
5MAP2K72.76456300
6NTRK32.66613117
7MAPK132.54313460
8MAP4K22.50012107
9MAP3K42.48360517
10MAP3K92.45617514
11ARAF2.42586818
12MINK12.40551468
13NME12.33517916
14GRK52.22168390
15EPHA42.20381195
16UHMK12.10089592
17CDK192.08881266
18TNIK1.93912039
19PNCK1.83519501
20DYRK21.82844155
21NTRK21.77694477
22KSR21.68776889
23ERBB31.60629362
24LIMK11.57741055
25PAK61.57592891
26FRK1.53112480
27STK161.49501455
28MUSK1.45986072
29PLK21.42485347
30NUAK11.37579284
31WEE11.36706763
32BMPR1B1.36133510
33STK391.31423884
34BMPR21.31266661
35KSR11.30598661
36MAP2K41.29447712
37NTRK11.28876097
38SRPK11.28042118
39MST41.25382010
40GRK71.22040052
41PHKG11.21779332
42PHKG21.21779332
43BCKDK1.20991054
44SIK31.18850834
45CDK51.18796232
46ACVR1B1.17559928
47MAPKAPK51.17373680
48BCR1.16690851
49BRAF1.16132582
50WNK31.15829597
51GRK11.15326931
52INSRR1.15034148
53OXSR11.12873855
54EPHA31.10081800
55PLK31.09077319
56CDK141.06475836
57CAMK2A1.04846310
58PRPF4B1.04696501
59DAPK11.02880078
60CSNK1G30.98857402
61CDK180.98732252
62CSNK1G20.97979089
63ZAK0.97066226
64PRKCG0.96752673
65FES0.95812526
66DYRK1A0.94924896
67CAMK2B0.94265608
68WNK40.94087877
69EIF2AK30.92752156
70SIK20.92749053
71CDK150.91917022
72CDK80.91830951
73DAPK20.90734887
74MKNK20.89044713
75MAP3K60.85822473
76MKNK10.85759091
77CDK11A0.85476867
78PTK2B0.84626339
79CCNB10.83052462
80VRK20.82673507
81BRSK20.82138786
82RIPK40.80162103
83PLK40.79726825
84EIF2AK10.77015596
85TSSK60.76333507
86ADRBK10.76182758
87VRK10.75215333
88PRKD30.75158726
89MAP3K50.73691471
90RPS6KA40.73035295
91ADRBK20.71901898
92DYRK1B0.70865421
93MOS0.67285285
94OBSCN0.63250202
95LATS20.63054744
96CAMK2D0.62388691
97SGK2230.62026125
98SGK4940.62026125
99RAF10.61988754
100PRKCE0.58915336
101ROCK20.58479078
102CSNK1G10.55211028
103FGR0.54600955
104CAMKK20.54542345
105NEK10.51648360
106TXK0.50457745
107CAMK2G0.49742633
108PRKG10.49723145
109PASK0.49677778
110PLK10.49036383
111PDK20.48488982
112PINK10.48202345
113CSNK1A1L0.46712946
114IRAK20.46622106
115AKT30.45181911
116AURKA0.44818675
117PAK30.44552413
118RPS6KA50.44067715
119IRAK10.42962196
120CSNK1A10.42571853
121EPHB20.42108848
122PRKACA0.41318726
123TAOK30.41149409
124DYRK30.40416395
125CAMK10.39212424
126SGK20.38943620
127MARK20.38859396
128CSNK1E0.38770318
129MYLK0.38575834
130TYRO30.36354097
131CSNK2A10.35946895
132MAPK150.35623552
133LMTK20.34383730
134PDK40.33928900
135PDK30.33928900
136TLK10.33858004
137BRSK10.33079402
138PRKCZ0.33078610
139PKN10.32883990
140CDK30.30366262
141ILK0.28798432
142CAMKK10.28080483

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001904.24644448
2Parkinsons disease_Homo sapiens_hsa050123.68650087
3Nicotine addiction_Homo sapiens_hsa050333.14177726
4Synaptic vesicle cycle_Homo sapiens_hsa047212.96467978
5Alzheimers disease_Homo sapiens_hsa050102.95624085
6Huntingtons disease_Homo sapiens_hsa050162.76306486
7Collecting duct acid secretion_Homo sapiens_hsa049662.34537589
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.29735793
9Cardiac muscle contraction_Homo sapiens_hsa042602.26042904
10GABAergic synapse_Homo sapiens_hsa047272.15882241
11Morphine addiction_Homo sapiens_hsa050321.96025243
12Circadian entrainment_Homo sapiens_hsa047131.94380315
13Glutamatergic synapse_Homo sapiens_hsa047241.93620501
14Proteasome_Homo sapiens_hsa030501.90073637
15Propanoate metabolism_Homo sapiens_hsa006401.88831093
16Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.85897050
17Serotonergic synapse_Homo sapiens_hsa047261.84462803
18Olfactory transduction_Homo sapiens_hsa047401.80535479
19Dopaminergic synapse_Homo sapiens_hsa047281.79636210
20Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.75069709
21Long-term potentiation_Homo sapiens_hsa047201.74070651
22RNA polymerase_Homo sapiens_hsa030201.68729474
23Butanoate metabolism_Homo sapiens_hsa006501.67074282
24Taste transduction_Homo sapiens_hsa047421.63702601
25Vibrio cholerae infection_Homo sapiens_hsa051101.63529429
26Amphetamine addiction_Homo sapiens_hsa050311.62993117
27Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.59585710
28Ribosome_Homo sapiens_hsa030101.57313275
29Protein export_Homo sapiens_hsa030601.56294440
30Long-term depression_Homo sapiens_hsa047301.49072284
31Cholinergic synapse_Homo sapiens_hsa047251.44078522
32Insulin secretion_Homo sapiens_hsa049111.42320177
33Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.41912089
34Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.41743191
35Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.40737520
36Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.32499645
37Maturity onset diabetes of the young_Homo sapiens_hsa049501.27147193
38Salivary secretion_Homo sapiens_hsa049701.22338728
39SNARE interactions in vesicular transport_Homo sapiens_hsa041301.21746498
40Phototransduction_Homo sapiens_hsa047441.17044479
41Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.16106384
42Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.15964816
43Cocaine addiction_Homo sapiens_hsa050301.14693283
44Renin secretion_Homo sapiens_hsa049241.14671080
45Axon guidance_Homo sapiens_hsa043601.09106173
46Oocyte meiosis_Homo sapiens_hsa041141.07035068
47Fanconi anemia pathway_Homo sapiens_hsa034601.05853181
48Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.05737230
49Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.04442624
50Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.03771347
51Oxytocin signaling pathway_Homo sapiens_hsa049211.03095095
52Gap junction_Homo sapiens_hsa045401.02945360
53Gastric acid secretion_Homo sapiens_hsa049711.02727551
54Homologous recombination_Homo sapiens_hsa034401.02368319
55Calcium signaling pathway_Homo sapiens_hsa040201.00040494
56Mismatch repair_Homo sapiens_hsa034300.99950125
57GnRH signaling pathway_Homo sapiens_hsa049120.98729071
58Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.96841279
59Non-homologous end-joining_Homo sapiens_hsa034500.92502861
60Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.87800287
61Aldosterone synthesis and secretion_Homo sapiens_hsa049250.87477425
62Peroxisome_Homo sapiens_hsa041460.84681015
63Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.78271449
64Basal transcription factors_Homo sapiens_hsa030220.77257092
65Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.76583337
66Melanogenesis_Homo sapiens_hsa049160.75934246
67Tryptophan metabolism_Homo sapiens_hsa003800.75452187
68Pyruvate metabolism_Homo sapiens_hsa006200.75021586
69Nitrogen metabolism_Homo sapiens_hsa009100.74944423
70Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.73654803
71Alcoholism_Homo sapiens_hsa050340.71969813
72Ether lipid metabolism_Homo sapiens_hsa005650.71568212
73Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.67595539
74Folate biosynthesis_Homo sapiens_hsa007900.67122548
75Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.64699935
76Cysteine and methionine metabolism_Homo sapiens_hsa002700.64507057
77Metabolic pathways_Homo sapiens_hsa011000.63715815
78Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.62720107
79Purine metabolism_Homo sapiens_hsa002300.62711906
80Rheumatoid arthritis_Homo sapiens_hsa053230.61855463
81cAMP signaling pathway_Homo sapiens_hsa040240.61547489
82* RNA transport_Homo sapiens_hsa030130.61484586
83Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.61397863
84Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.59831990
85Estrogen signaling pathway_Homo sapiens_hsa049150.59141638
86beta-Alanine metabolism_Homo sapiens_hsa004100.58170076
87Phagosome_Homo sapiens_hsa041450.56826659
88Linoleic acid metabolism_Homo sapiens_hsa005910.55565849
89Regulation of autophagy_Homo sapiens_hsa041400.55157663
90Vascular smooth muscle contraction_Homo sapiens_hsa042700.55102601
91cGMP-PKG signaling pathway_Homo sapiens_hsa040220.54760567
92Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.53514434
93Spliceosome_Homo sapiens_hsa030400.49850076
94Pyrimidine metabolism_Homo sapiens_hsa002400.49683849
95Sphingolipid signaling pathway_Homo sapiens_hsa040710.49588743
96ErbB signaling pathway_Homo sapiens_hsa040120.49133380
97VEGF signaling pathway_Homo sapiens_hsa043700.48469916
98Renal cell carcinoma_Homo sapiens_hsa052110.48309795
99Primary bile acid biosynthesis_Homo sapiens_hsa001200.47413259
100Ras signaling pathway_Homo sapiens_hsa040140.46642719
101Steroid biosynthesis_Homo sapiens_hsa001000.43265930
102Dorso-ventral axis formation_Homo sapiens_hsa043200.42787684
103Wnt signaling pathway_Homo sapiens_hsa043100.42735511
104Arginine and proline metabolism_Homo sapiens_hsa003300.42708558
105Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.42182375
106Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.41494072
107Nucleotide excision repair_Homo sapiens_hsa034200.40722023
108Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.40693877
109Glutathione metabolism_Homo sapiens_hsa004800.40532476
110Glioma_Homo sapiens_hsa052140.40483865
111Circadian rhythm_Homo sapiens_hsa047100.40351208
112Pancreatic secretion_Homo sapiens_hsa049720.38785470
113Selenocompound metabolism_Homo sapiens_hsa004500.38508099
114Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.37645793
115MAPK signaling pathway_Homo sapiens_hsa040100.36837442
116alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.35359137
117RNA degradation_Homo sapiens_hsa030180.33459831
118Type I diabetes mellitus_Homo sapiens_hsa049400.33286868
119Phospholipase D signaling pathway_Homo sapiens_hsa040720.33153397
120Ovarian steroidogenesis_Homo sapiens_hsa049130.32986301
121Phosphatidylinositol signaling system_Homo sapiens_hsa040700.32888242
122Base excision repair_Homo sapiens_hsa034100.32864912
123Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.32564766
124Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.32331450
125Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.32036717
126Caffeine metabolism_Homo sapiens_hsa002320.31247835
127Fatty acid elongation_Homo sapiens_hsa000620.31148214
128Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.30987993
129Chemical carcinogenesis_Homo sapiens_hsa052040.30801113
130Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.30166808
131Legionellosis_Homo sapiens_hsa051340.30039291
132Sphingolipid metabolism_Homo sapiens_hsa006000.29865832
133Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.29772926
134Endocytosis_Homo sapiens_hsa041440.29539406
135Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.28711102
136Choline metabolism in cancer_Homo sapiens_hsa052310.28655704
137Hedgehog signaling pathway_Homo sapiens_hsa043400.28192167
138Fatty acid metabolism_Homo sapiens_hsa012120.27654282
139Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.27128537
140mRNA surveillance pathway_Homo sapiens_hsa030150.25410817
141Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.25269836
142Colorectal cancer_Homo sapiens_hsa052100.25120939
143Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.23528799

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