EIF1AD

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein K11-linked deubiquitination (GO:0035871)5.87997343
2DNA strand elongation involved in DNA replication (GO:0006271)5.07986776
3DNA deamination (GO:0045006)4.95780793
4telomere maintenance via semi-conservative replication (GO:0032201)4.89416121
5DNA strand elongation (GO:0022616)4.79881169
6protein K6-linked ubiquitination (GO:0085020)4.78013088
7maturation of 5.8S rRNA (GO:0000460)4.72150248
8ribosomal small subunit assembly (GO:0000028)4.59745439
9DNA replication initiation (GO:0006270)4.57410563
10DNA double-strand break processing (GO:0000729)4.49914467
11maturation of SSU-rRNA (GO:0030490)4.42266116
12DNA replication checkpoint (GO:0000076)4.40458209
13DNA unwinding involved in DNA replication (GO:0006268)4.37062101
14telomere maintenance via recombination (GO:0000722)4.29191170
15formation of translation preinitiation complex (GO:0001731)4.18148239
16replication fork processing (GO:0031297)4.06786839
17viral transcription (GO:0019083)4.04793644
18mitotic recombination (GO:0006312)4.02551587
19nucleobase biosynthetic process (GO:0046112)4.01146617
20translational termination (GO:0006415)3.99315731
21proteasome assembly (GO:0043248)3.96754351
22ribosomal small subunit biogenesis (GO:0042274)3.96307091
23ribosomal large subunit biogenesis (GO:0042273)3.88940313
24telomere maintenance via telomere lengthening (GO:0010833)3.84779315
25ribosome biogenesis (GO:0042254)3.83346571
26ribonucleoprotein complex biogenesis (GO:0022613)3.82412177
27purine nucleobase biosynthetic process (GO:0009113)3.81906716
28nucleotide-excision repair, DNA gap filling (GO:0006297)3.74914849
29respiratory chain complex IV assembly (GO:0008535)3.73283923
30protein localization to kinetochore (GO:0034501)3.73011019
31negative regulation of retinoic acid receptor signaling pathway (GO:0048387)3.72680451
32regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.70842443
33translational elongation (GO:0006414)3.68360134
34CENP-A containing nucleosome assembly (GO:0034080)3.67856858
35negative regulation of DNA-dependent DNA replication (GO:2000104)3.67327316
36deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.64510046
37* translational initiation (GO:0006413)3.64087492
38chromatin remodeling at centromere (GO:0031055)3.60297573
39keratinocyte development (GO:0003334)3.59102415
40negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.58004893
41spliceosomal snRNP assembly (GO:0000387)3.56587760
42DNA replication-dependent nucleosome assembly (GO:0006335)3.55685537
43DNA replication-dependent nucleosome organization (GO:0034723)3.55685537
44SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.55255074
45RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.55199062
46rRNA processing (GO:0006364)3.55025099
47mitotic metaphase plate congression (GO:0007080)3.54817090
48mitotic nuclear envelope disassembly (GO:0007077)3.53931217
49peptidyl-histidine modification (GO:0018202)3.52040615
50ribosome assembly (GO:0042255)3.51732329
51rRNA modification (GO:0000154)3.49095131
52pseudouridine synthesis (GO:0001522)3.47525910
53folic acid-containing compound biosynthetic process (GO:0009396)3.47516034
54cotranslational protein targeting to membrane (GO:0006613)3.45024713
55protein targeting to ER (GO:0045047)3.43966282
56regulation of retinoic acid receptor signaling pathway (GO:0048385)3.42666104
57rRNA metabolic process (GO:0016072)3.42609915
58anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.42461693
59regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.40907285
60protein-cofactor linkage (GO:0018065)3.40555655
61kinetochore organization (GO:0051383)3.40094463
62nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.38568240
63IMP biosynthetic process (GO:0006188)3.37199213
64protein localization to chromosome, centromeric region (GO:0071459)3.36644605
65positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.36108760
66DNA catabolic process, exonucleolytic (GO:0000738)3.33549107
67DNA replication-independent nucleosome organization (GO:0034724)3.31636145
68DNA replication-independent nucleosome assembly (GO:0006336)3.31636145
69cytochrome complex assembly (GO:0017004)3.30661812
70dolichol-linked oligosaccharide biosynthetic process (GO:0006488)3.29713071
71negative regulation of ligase activity (GO:0051352)3.29575118
72negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.29575118
73kinetochore assembly (GO:0051382)3.28884389
74rRNA methylation (GO:0031167)3.28693957
75membrane disassembly (GO:0030397)3.28170924
76nuclear envelope disassembly (GO:0051081)3.28170924
77protein localization to endoplasmic reticulum (GO:0070972)3.25022158
78establishment of protein localization to endoplasmic reticulum (GO:0072599)3.23448993
79transcription-coupled nucleotide-excision repair (GO:0006283)3.21934131
80viral life cycle (GO:0019058)3.19948694
81translation (GO:0006412)3.18490872
82regulation of DNA endoreduplication (GO:0032875)3.17872508
83cellular protein complex disassembly (GO:0043624)3.17245082
84somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.16468511
85isotype switching (GO:0045190)3.16468511
86somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.16468511
87recombinational repair (GO:0000725)3.13729423
88double-strand break repair via homologous recombination (GO:0000724)3.13656259
89G1/S transition of mitotic cell cycle (GO:0000082)3.12641634
90cell cycle G1/S phase transition (GO:0044843)3.12641634
91maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.11639054
92synapsis (GO:0007129)3.11604244
93nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.09347917
94spliceosomal complex assembly (GO:0000245)3.07106601
95termination of RNA polymerase III transcription (GO:0006386)3.05998060
96transcription elongation from RNA polymerase III promoter (GO:0006385)3.05998060
97viral mRNA export from host cell nucleus (GO:0046784)3.05986634
98DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.04935227
99establishment of integrated proviral latency (GO:0075713)3.03322038
100protein complex biogenesis (GO:0070271)3.02590899
101cullin deneddylation (GO:0010388)3.01314640
102IMP metabolic process (GO:0046040)3.00304924
103intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.00165123
104signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.00165123
105mitochondrial respiratory chain complex assembly (GO:0033108)3.00128930
106metaphase plate congression (GO:0051310)2.99369224
107positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.99124758
108signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.98675456
109signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.98675456
110signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.98675456
111lactate metabolic process (GO:0006089)2.97043237
112cellular component biogenesis (GO:0044085)2.96869484
113protein deneddylation (GO:0000338)2.94994541
114histone exchange (GO:0043486)2.94943845
115signal transduction involved in DNA damage checkpoint (GO:0072422)2.94579859
116signal transduction involved in DNA integrity checkpoint (GO:0072401)2.94579859
117regulation of double-strand break repair via homologous recombination (GO:0010569)2.93811629
118attachment of spindle microtubules to kinetochore (GO:0008608)2.93536482
119regulation of hexokinase activity (GO:1903299)2.93520369
120regulation of glucokinase activity (GO:0033131)2.93520369
121protein complex disassembly (GO:0043241)2.91625489
122signal transduction involved in cell cycle checkpoint (GO:0072395)2.91234791
123mitotic sister chromatid segregation (GO:0000070)2.89701130
124serotonin receptor signaling pathway (GO:0007210)2.89229869
125mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.89119651
126mitochondrial respiratory chain complex I assembly (GO:0032981)2.89119651
127NADH dehydrogenase complex assembly (GO:0010257)2.89119651
128exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.87955937
129regulation of cellular amino acid metabolic process (GO:0006521)2.87521674
130somatic hypermutation of immunoglobulin genes (GO:0016446)2.87503342
131somatic diversification of immune receptors via somatic mutation (GO:0002566)2.87503342
132positive regulation of ligase activity (GO:0051351)2.86434294
133nuclear-transcribed mRNA catabolic process (GO:0000956)2.85713779
134establishment of chromosome localization (GO:0051303)2.84938516
135termination of RNA polymerase II transcription (GO:0006369)2.84889202
136RNA splicing, via transesterification reactions (GO:0000375)2.84192083
137negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.84171681
138L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.81789125
139tRNA processing (GO:0008033)2.77399559
140regulation of nuclear cell cycle DNA replication (GO:0033262)2.77116326
141mitochondrial RNA metabolic process (GO:0000959)2.76122757
142DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.73916836
143signal peptide processing (GO:0006465)2.73747365
144mannosylation (GO:0097502)2.68034265
145platelet dense granule organization (GO:0060155)2.66186294
146water-soluble vitamin biosynthetic process (GO:0042364)2.65229167
147pteridine-containing compound biosynthetic process (GO:0042559)2.64129890
148positive regulation of cell cycle arrest (GO:0071158)2.60641345
149transcription elongation from RNA polymerase I promoter (GO:0006362)2.57708402
150RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.56891008
151tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.56891008
152regulation of ubiquitin-protein transferase activity (GO:0051438)2.55943772
153protein K63-linked deubiquitination (GO:0070536)2.54516686
154tryptophan catabolic process (GO:0006569)2.53993012
155indole-containing compound catabolic process (GO:0042436)2.53993012
156indolalkylamine catabolic process (GO:0046218)2.53993012
157negative regulation of mast cell activation (GO:0033004)2.52608138
158double-strand break repair (GO:0006302)2.52441166
159rRNA catabolic process (GO:0016075)2.51884566
160somatic diversification of immunoglobulins (GO:0016445)2.50791417
161negative regulation of calcium ion transport into cytosol (GO:0010523)2.50767360
162regulation of ligase activity (GO:0051340)2.50674850
163termination of RNA polymerase I transcription (GO:0006363)2.49612685
164tRNA metabolic process (GO:0006399)2.46499057
165regulation of centriole replication (GO:0046599)2.45179027
166regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.45047495
167regulation of mitotic spindle checkpoint (GO:1903504)2.45047495

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.94353490
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.31761490
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.97327108
4FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.77171116
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.53420292
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.32869042
7FOXM1_23109430_ChIP-Seq_U2OS_Human3.30087388
8GABP_17652178_ChIP-ChIP_JURKAT_Human3.15676906
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.08972326
10EST1_17652178_ChIP-ChIP_JURKAT_Human3.08553790
11* ETS1_20019798_ChIP-Seq_JURKAT_Human2.96146176
12* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.95244701
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.95222646
14MYC_19079543_ChIP-ChIP_MESCs_Mouse2.89435209
15MYC_19030024_ChIP-ChIP_MESCs_Mouse2.85763543
16ZNF274_21170338_ChIP-Seq_K562_Hela2.85011237
17CREB1_15753290_ChIP-ChIP_HEK293T_Human2.72104307
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.60761236
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.50701714
20* XRN2_22483619_ChIP-Seq_HELA_Human2.40414301
21ELF1_17652178_ChIP-ChIP_JURKAT_Human2.35033706
22* VDR_23849224_ChIP-Seq_CD4+_Human2.33449122
23NELFA_20434984_ChIP-Seq_ESCs_Mouse2.31801307
24BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.31644206
25CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.26720552
26DCP1A_22483619_ChIP-Seq_HELA_Human2.09710726
27E2F1_18555785_ChIP-Seq_MESCs_Mouse2.08353941
28* FOXP3_21729870_ChIP-Seq_TREG_Human2.05691512
29* GABP_19822575_ChIP-Seq_HepG2_Human1.97095415
30MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.96374444
31SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.96161958
32SALL1_21062744_ChIP-ChIP_HESCs_Human1.94490343
33HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.92409659
34SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.89701220
35AR_21909140_ChIP-Seq_LNCAP_Human1.88325697
36* TTF2_22483619_ChIP-Seq_HELA_Human1.87346638
37THAP11_20581084_ChIP-Seq_MESCs_Mouse1.86988762
38FLI1_27457419_Chip-Seq_LIVER_Mouse1.81441836
39MYCN_18555785_ChIP-Seq_MESCs_Mouse1.81414145
40E2F1_21310950_ChIP-Seq_MCF-7_Human1.81029724
41MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.79429909
42VDR_22108803_ChIP-Seq_LS180_Human1.74533475
43TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.74215221
44PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.74151651
45YY1_21170310_ChIP-Seq_MESCs_Mouse1.73155451
46POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.69378654
47EWS_26573619_Chip-Seq_HEK293_Human1.65139822
48NANOG_18555785_ChIP-Seq_MESCs_Mouse1.65085436
49MYC_22102868_ChIP-Seq_BL_Human1.62715813
50* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.59775050
51E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.59589071
52CIITA_25753668_ChIP-Seq_RAJI_Human1.59334945
53ELK1_19687146_ChIP-ChIP_HELA_Human1.58793184
54ZFX_18555785_ChIP-Seq_MESCs_Mouse1.56595315
55HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.54893283
56HOXB4_20404135_ChIP-ChIP_EML_Mouse1.52800929
57SRF_21415370_ChIP-Seq_HL-1_Mouse1.50704528
58CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.48366295
59CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.48167806
60ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.47227568
61* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.46030622
62KDM5A_27292631_Chip-Seq_BREAST_Human1.43441118
63YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.41848062
64EGR1_19374776_ChIP-ChIP_THP-1_Human1.40302158
65* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.39820188
66PCGF2_27294783_Chip-Seq_ESCs_Mouse1.37835956
67POU3F2_20337985_ChIP-ChIP_501MEL_Human1.37345610
68NOTCH1_21737748_ChIP-Seq_TLL_Human1.34803697
69* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.33931067
70ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.33819891
71EGR1_23403033_ChIP-Seq_LIVER_Mouse1.33307468
72EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.31725930
73MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.31717106
74CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.30540039
75CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.24498686
76ER_23166858_ChIP-Seq_MCF-7_Human1.24129040
77VDR_21846776_ChIP-Seq_THP-1_Human1.22343677
78SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.22117465
79KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.20750303
80TP53_22573176_ChIP-Seq_HFKS_Human1.20606719
81KLF4_18555785_ChIP-Seq_MESCs_Mouse1.19427245
82POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.19249571
83PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.19042639
84ZFP57_27257070_Chip-Seq_ESCs_Mouse1.18673199
85HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.18540829
86GBX2_23144817_ChIP-Seq_PC3_Human1.18366258
87STAT3_1855785_ChIP-Seq_MESCs_Mouse1.18254240
88DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.17097755
89TFEB_21752829_ChIP-Seq_HELA_Human1.16595294
90FUS_26573619_Chip-Seq_HEK293_Human1.14528669
91EZH2_27294783_Chip-Seq_NPCs_Mouse1.12158373
92E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.11913273
93IGF1R_20145208_ChIP-Seq_DFB_Human1.08723820
94CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.07707236
95SPI1_23547873_ChIP-Seq_NB4_Human1.07131879
96TP63_19390658_ChIP-ChIP_HaCaT_Human1.05989799
97SMAD_19615063_ChIP-ChIP_OVARY_Human1.05293350
98KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.05026719
99SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.04451032
100TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.03506318
101PADI4_21655091_ChIP-ChIP_MCF-7_Human1.03305856
102* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.03275217
103P300_19829295_ChIP-Seq_ESCs_Human1.02727773
104CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.02160461
105MYC_18940864_ChIP-ChIP_HL60_Human1.01414962
106GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.00718976
107NFE2_27457419_Chip-Seq_LIVER_Mouse0.99732980
108KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.99008329
109CRX_20693478_ChIP-Seq_RETINA_Mouse0.98936785
110CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.98810056
111* ELK1_22589737_ChIP-Seq_MCF10A_Human0.97835008
112POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.95176718
113SUZ12_27294783_Chip-Seq_NPCs_Mouse0.93584916
114CDX2_22108803_ChIP-Seq_LS180_Human0.93419970
115* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.91842154
116TAF15_26573619_Chip-Seq_HEK293_Human0.91058250
117HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.91012770
118CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.90937192
119HOXB7_26014856_ChIP-Seq_BT474_Human0.90815219
120FOXA1_21572438_ChIP-Seq_LNCaP_Human0.90680985
121SOX2_19829295_ChIP-Seq_ESCs_Human0.90610569
122NANOG_19829295_ChIP-Seq_ESCs_Human0.90610569
123SOX2_18555785_ChIP-Seq_MESCs_Mouse0.89687169
124FOXA1_25329375_ChIP-Seq_VCAP_Human0.89266434
125FOXA1_27270436_Chip-Seq_PROSTATE_Human0.89266434
126* ELF5_23300383_ChIP-Seq_T47D_Human0.88686508
127GATA3_26560356_Chip-Seq_TH2_Human0.88520443
128* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.88347454
129PHF8_20622853_ChIP-Seq_HELA_Human0.88058353
130BCAT_22108803_ChIP-Seq_LS180_Human0.87135385
131CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.86044197
132TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.84986445
133POU5F1_16153702_ChIP-ChIP_HESCs_Human0.84970132
134RBPJ_21746931_ChIP-Seq_IB4_Human0.82834920
135SRY_22984422_ChIP-ChIP_TESTIS_Rat0.82723684
136GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.82095029
137CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.81934297
138IRF1_19129219_ChIP-ChIP_H3396_Human0.81731448
139CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.81322884
140IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.79687373
141GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.79617337
142* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.76406375
143SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.74556122
144OCT4_18692474_ChIP-Seq_MEFs_Mouse0.73989962
145DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.72183588
146GATA1_22383799_ChIP-Seq_G1ME_Mouse0.71777867

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.75084687
2MP0004957_abnormal_blastocyst_morpholog4.54227466
3MP0010094_abnormal_chromosome_stability4.46455872
4MP0003111_abnormal_nucleus_morphology4.23640524
5MP0003077_abnormal_cell_cycle3.84492466
6MP0008057_abnormal_DNA_replication3.78761202
7MP0003195_calcinosis3.65428595
8MP0008058_abnormal_DNA_repair3.36514048
9MP0002396_abnormal_hematopoietic_system2.87072317
10MP0008932_abnormal_embryonic_tissue2.81169019
11MP0002138_abnormal_hepatobiliary_system2.77524704
12MP0008007_abnormal_cellular_replicative2.60527123
13MP0002254_reproductive_system_inflammat2.60088623
14MP0000372_irregular_coat_pigmentation2.44782863
15MP0003786_premature_aging2.11909754
16MP0000350_abnormal_cell_proliferation2.10435035
17MP0000490_abnormal_crypts_of2.10023465
18MP0005310_abnormal_salivary_gland2.07397598
19MP0001730_embryonic_growth_arrest2.06823505
20MP0003950_abnormal_plasma_membrane2.04006614
21MP0005084_abnormal_gallbladder_morpholo2.03029441
22MP0008875_abnormal_xenobiotic_pharmacok1.85264637
23MP0002163_abnormal_gland_morphology1.80527664
24MP0003646_muscle_fatigue1.79301499
25MP0009697_abnormal_copulation1.73447616
26MP0009333_abnormal_splenocyte_physiolog1.70455199
27MP0001764_abnormal_homeostasis1.63140773
28MP0008877_abnormal_DNA_methylation1.62305949
29MP0008872_abnormal_physiological_respon1.61290857
30MP0002019_abnormal_tumor_incidence1.57574639
31MP0000516_abnormal_urinary_system1.55497263
32MP0005367_renal/urinary_system_phenotyp1.55497263
33MP0001672_abnormal_embryogenesis/_devel1.55153961
34MP0005380_embryogenesis_phenotype1.55153961
35MP0010352_gastrointestinal_tract_polyps1.54507099
36MP0001697_abnormal_embryo_size1.54446566
37MP0003718_maternal_effect1.52986697
38MP0000613_abnormal_salivary_gland1.51231552
39MP0000313_abnormal_cell_death1.50520582
40MP0005379_endocrine/exocrine_gland_phen1.50488091
41MP0005645_abnormal_hypothalamus_physiol1.49040687
42MP0003763_abnormal_thymus_physiology1.46840043
43MP0002080_prenatal_lethality1.45661878
44MP0003186_abnormal_redox_activity1.45251406
45MP0001873_stomach_inflammation1.45209816
46MP0010234_abnormal_vibrissa_follicle1.43272063
47MP0002876_abnormal_thyroid_physiology1.42851959
48MP0004808_abnormal_hematopoietic_stem1.40437648
49MP0003984_embryonic_growth_retardation1.40369800
50MP0010307_abnormal_tumor_latency1.39991047
51MP0010030_abnormal_orbit_morphology1.39081534
52MP0005397_hematopoietic_system_phenotyp1.37939391
53MP0001545_abnormal_hematopoietic_system1.37939391
54MP0002398_abnormal_bone_marrow1.37469606
55MP0003123_paternal_imprinting1.36584284
56MP0002088_abnormal_embryonic_growth/wei1.36329489
57MP0003315_abnormal_perineum_morphology1.35209028
58MP0002722_abnormal_immune_system1.29535796
59MP0000703_abnormal_thymus_morphology1.28219806
60MP0002085_abnormal_embryonic_tissue1.27720762
61MP0000689_abnormal_spleen_morphology1.26721019
62MP0003806_abnormal_nucleotide_metabolis1.25963443
63MP0004043_abnormal_pH_regulation1.25635045
64MP0000427_abnormal_hair_cycle1.23255616
65MP0010678_abnormal_skin_adnexa1.22459782
66MP0002277_abnormal_respiratory_mucosa1.18985695
67MP0002837_dystrophic_cardiac_calcinosis1.17683817
68MP0005075_abnormal_melanosome_morpholog1.15731772
69MP0006072_abnormal_retinal_apoptosis1.15138078
70MP0000015_abnormal_ear_pigmentation1.15126133
71MP0002132_abnormal_respiratory_system1.14154371
72MP0002160_abnormal_reproductive_system1.13978742
73MP0005551_abnormal_eye_electrophysiolog1.13569730
74MP0002429_abnormal_blood_cell1.12497920
75MP0005395_other_phenotype1.11495745
76MP0009053_abnormal_anal_canal1.11317554
77MP0002086_abnormal_extraembryonic_tissu1.11075323
78MP0004197_abnormal_fetal_growth/weight/1.10837940
79MP0003436_decreased_susceptibility_to1.10521662
80MP0005253_abnormal_eye_physiology1.09022422
81MP0001835_abnormal_antigen_presentation1.08271449
82MP0000858_altered_metastatic_potential1.07796310
83MP0002210_abnormal_sex_determination1.07577617
84MP0005083_abnormal_biliary_tract1.06866359
85MP0002084_abnormal_developmental_patter1.06737587
86MP0001853_heart_inflammation1.06301876
87MP0002938_white_spotting1.05085662
88MP0005647_abnormal_sex_gland1.03914711
89MP0000716_abnormal_immune_system1.00089005
90MP0003567_abnormal_fetal_cardiomyocyte0.99851728
91MP0000383_abnormal_hair_follicle0.98319366
92MP0005410_abnormal_fertilization0.98231071
93MP0008995_early_reproductive_senescence0.97836676
94MP0001145_abnormal_male_reproductive0.97713988
95MP0002693_abnormal_pancreas_physiology0.97314604
96MP0002139_abnormal_hepatobiliary_system0.96246305
97MP0001984_abnormal_olfaction0.96053342
98MP0006054_spinal_hemorrhage0.95429066
99MP0001661_extended_life_span0.94708157
100MP0002166_altered_tumor_susceptibility0.92265142
101MP0005332_abnormal_amino_acid0.91883788
102MP0001293_anophthalmia0.90709087
103MP0000358_abnormal_cell_content/0.90314751
104MP0001800_abnormal_humoral_immune0.89886071
105MP0005671_abnormal_response_to0.88107403
106MP0002420_abnormal_adaptive_immunity0.87950115
107MP0006036_abnormal_mitochondrial_physio0.87108920
108MP0009379_abnormal_foot_pigmentation0.86865691
109MP0001819_abnormal_immune_cell0.86352454
110MP0003936_abnormal_reproductive_system0.84500266
111MP0006292_abnormal_olfactory_placode0.83174848
112MP0005076_abnormal_cell_differentiation0.83125659
113MP0009785_altered_susceptibility_to0.82635165
114MP0001986_abnormal_taste_sensitivity0.82595167
115MP0005389_reproductive_system_phenotype0.82488905
116MP0002405_respiratory_system_inflammati0.81851142
117MP0002452_abnormal_antigen_presenting0.81445095
118MP0005220_abnormal_exocrine_pancreas0.80317894
119MP0005174_abnormal_tail_pigmentation0.79514064
120MP0000647_abnormal_sebaceous_gland0.79492647
121MP0000537_abnormal_urethra_morphology0.79379362
122MP0001919_abnormal_reproductive_system0.79329514
123MP0002102_abnormal_ear_morphology0.79310010
124MP0004142_abnormal_muscle_tone0.79083673
125MP0003890_abnormal_embryonic-extraembry0.78799335
126MP0002723_abnormal_immune_serum0.77455861
127MP0000685_abnormal_immune_system0.77167250
128MP0002090_abnormal_vision0.76988791
129MP0002095_abnormal_skin_pigmentation0.76797878
130MP0001929_abnormal_gametogenesis0.76535876
131MP0003943_abnormal_hepatobiliary_system0.76336190
132MP0000653_abnormal_sex_gland0.75557472
133MP0002736_abnormal_nociception_after0.75269186
134MP0001119_abnormal_female_reproductive0.75254589
135MP0006035_abnormal_mitochondrial_morpho0.72092875
136MP0003119_abnormal_digestive_system0.71813329
137MP0000477_abnormal_intestine_morphology0.71704725
138MP0005501_abnormal_skin_physiology0.71699374
139MP0005025_abnormal_response_to0.71251785
140MP0002111_abnormal_tail_morphology0.70851386
141MP0005384_cellular_phenotype0.69828799
142MP0003221_abnormal_cardiomyocyte_apopto0.68627611
143MP0003941_abnormal_skin_development0.67557598
144MP0005000_abnormal_immune_tolerance0.65895724
145MP0002928_abnormal_bile_duct0.65428194
146MP0004147_increased_porphyrin_level0.65178420
147MP0001944_abnormal_pancreas_morphology0.65048056
148MP0005621_abnormal_cell_physiology0.65006028
149MP0002148_abnormal_hypersensitivity_rea0.64789369
150MP0002006_tumorigenesis0.64302391
151MP0003656_abnormal_erythrocyte_physiolo0.64264357
152MP0004145_abnormal_muscle_electrophysio0.64226528
153MP0000566_synostosis0.63042991
154MP0000465_gastrointestinal_hemorrhage0.62562743
155MP0000538_abnormal_urinary_bladder0.60244695
156MP0003698_abnormal_male_reproductive0.59124369
157MP0005266_abnormal_metabolism0.58996476
158MP0008873_increased_physiological_sensi0.58901506
159MP0005670_abnormal_white_adipose0.58448671
160MP0005408_hypopigmentation0.58167283

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)4.66021886
2Abnormal number of erythroid precursors (HP:0012131)4.56788143
3Birth length less than 3rd percentile (HP:0003561)4.43153478
4Reticulocytopenia (HP:0001896)4.34125169
5Degeneration of anterior horn cells (HP:0002398)4.04758826
6Abnormality of the anterior horn cell (HP:0006802)4.04758826
7Oral leukoplakia (HP:0002745)3.97681574
8Carpal bone hypoplasia (HP:0001498)3.47138553
9Breast hypoplasia (HP:0003187)3.45448789
10Rough bone trabeculation (HP:0100670)3.43869986
11Aplastic anemia (HP:0001915)3.38821936
12Patellar aplasia (HP:0006443)3.19872553
13Macrocytic anemia (HP:0001972)3.11040640
14Microretrognathia (HP:0000308)3.09835696
15Chromsome breakage (HP:0040012)3.08608475
16Irregular epiphyses (HP:0010582)3.06768839
17Aplasia/Hypoplasia of the patella (HP:0006498)3.06433116
18Acute necrotizing encephalopathy (HP:0006965)3.04922147
19Pallor (HP:0000980)3.00000916
20Pancreatic cysts (HP:0001737)2.99936188
21Trismus (HP:0000211)2.98919450
22Progressive macrocephaly (HP:0004481)2.95988027
23Cerebral hypomyelination (HP:0006808)2.95075136
24Selective tooth agenesis (HP:0001592)2.87847487
25Acute encephalopathy (HP:0006846)2.86689508
26Chromosomal breakage induced by crosslinking agents (HP:0003221)2.79942232
27Aplasia/hypoplasia of the uterus (HP:0008684)2.77035751
28Abnormality of the preputium (HP:0100587)2.74221099
29Ketoacidosis (HP:0001993)2.72462769
30Premature graying of hair (HP:0002216)2.67652847
31Abnormality of chromosome stability (HP:0003220)2.62799370
32Meckel diverticulum (HP:0002245)2.61508419
33Multiple enchondromatosis (HP:0005701)2.59104475
3411 pairs of ribs (HP:0000878)2.58900745
35Thrombocytosis (HP:0001894)2.56309258
36Abnormality of the ileum (HP:0001549)2.54104481
37Glossoptosis (HP:0000162)2.54032124
38Abnormal mitochondria in muscle tissue (HP:0008316)2.52424773
39Neoplasm of the adrenal cortex (HP:0100641)2.52052826
40Type I transferrin isoform profile (HP:0003642)2.51776393
41Absent thumb (HP:0009777)2.50076412
42Hypoplasia of the uterus (HP:0000013)2.48055723
43Abnormal trabecular bone morphology (HP:0100671)2.46333800
44Large for gestational age (HP:0001520)2.46002449
45Congenital stationary night blindness (HP:0007642)2.45673727
46Attenuation of retinal blood vessels (HP:0007843)2.44671170
47Methylmalonic acidemia (HP:0002912)2.42035514
48Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.42011588
49True hermaphroditism (HP:0010459)2.40075866
50Breast carcinoma (HP:0003002)2.38745883
51Decreased activity of mitochondrial respiratory chain (HP:0008972)2.37794819
52Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.37794819
53Bone marrow hypocellularity (HP:0005528)2.36305756
54Myelodysplasia (HP:0002863)2.35812764
55Hyperinsulinemic hypoglycemia (HP:0000825)2.35462652
56Horseshoe kidney (HP:0000085)2.30185318
57Aplasia/Hypoplasia of the uvula (HP:0010293)2.28691965
58Pancreatic fibrosis (HP:0100732)2.27584784
59Colon cancer (HP:0003003)2.25621882
60Increased serum lactate (HP:0002151)2.25401148
61Hypothermia (HP:0002045)2.25199464
62Neoplasm of the pancreas (HP:0002894)2.25050283
63Abnormality of endocrine pancreas physiology (HP:0012093)2.23992582
64Abnormality of the pancreatic islet cells (HP:0006476)2.23992582
65Premature ovarian failure (HP:0008209)2.23917620
66Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.23326799
67Secondary amenorrhea (HP:0000869)2.23151976
68Cellular immunodeficiency (HP:0005374)2.22979918
69Pancreatic islet-cell hyperplasia (HP:0004510)2.22411656
70Sparse eyelashes (HP:0000653)2.22392170
71Conjunctival hamartoma (HP:0100780)2.21895343
72Agnosia (HP:0010524)2.21357116
73Abnormal number of incisors (HP:0011064)2.21356580
74Atrophy/Degeneration involving motor neurons (HP:0007373)2.20546313
75Microvesicular hepatic steatosis (HP:0001414)2.19369852
76Small intestinal stenosis (HP:0012848)2.18321390
77Duodenal stenosis (HP:0100867)2.18321390
78Petechiae (HP:0000967)2.17776696
79Reduced antithrombin III activity (HP:0001976)2.17222260
80IgM deficiency (HP:0002850)2.16703293
81Cleft eyelid (HP:0000625)2.16050779
82Clubbing of toes (HP:0100760)2.15897453
83Absent radius (HP:0003974)2.14834547
84Prominent metopic ridge (HP:0005487)2.14757136
85Pancytopenia (HP:0001876)2.14482031
86Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.14291121
87Abnormality of alanine metabolism (HP:0010916)2.14291121
88Hyperalaninemia (HP:0003348)2.14291121
89Progressive muscle weakness (HP:0003323)2.12891727
90Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.12868931
91Methylmalonic aciduria (HP:0012120)2.12633402
92Exertional dyspnea (HP:0002875)2.11818296
93Aplasia/Hypoplasia of the sacrum (HP:0008517)2.10402544
94Hyperglycemia (HP:0003074)2.09938101
95Poor head control (HP:0002421)2.09320243
96Tongue fasciculations (HP:0001308)2.08956027
97Hypoplasia of the capital femoral epiphysis (HP:0003090)2.08474372
98Impulsivity (HP:0100710)2.07627805
99Lactic acidosis (HP:0003128)2.07600393
100Increased hepatocellular lipid droplets (HP:0006565)2.07076723
101Pendular nystagmus (HP:0012043)2.07008216
102Cerebral edema (HP:0002181)2.04985413
1033-Methylglutaconic aciduria (HP:0003535)2.03942054
104Molar tooth sign on MRI (HP:0002419)2.03363956
105Abnormality of midbrain morphology (HP:0002418)2.03363956
106Hepatocellular necrosis (HP:0001404)2.03253044
107Lymphoma (HP:0002665)2.02353343
108Poikiloderma (HP:0001029)2.02327471
109Abnormality of the pons (HP:0007361)2.02136876
110Meningioma (HP:0002858)1.99513666
111Abnormality of the renal cortex (HP:0011035)1.99369186
112Hamartoma of the eye (HP:0010568)1.99189938
113Abnormality of the heme biosynthetic pathway (HP:0010472)1.99106535
114Neoplasm of the adrenal gland (HP:0100631)1.98289866
115Muscle fiber atrophy (HP:0100295)1.97050909
116Respiratory difficulties (HP:0002880)1.95366386
117Tracheoesophageal fistula (HP:0002575)1.95112015
118Abnormal pancreas size (HP:0012094)1.94994859
119Constricted visual fields (HP:0001133)1.94927585
120Triphalangeal thumb (HP:0001199)1.94922468
121Absent forearm bone (HP:0003953)1.94388625
122Aplasia involving forearm bones (HP:0009822)1.94388625
123Abnormality of DNA repair (HP:0003254)1.94245018
124Thyroiditis (HP:0100646)1.94189742
125Late onset (HP:0003584)1.94156122
126Absent epiphyses (HP:0010577)1.93908944
127Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.93908944
128CNS demyelination (HP:0007305)1.93504867
129Squamous cell carcinoma (HP:0002860)1.92070440
130Atresia of the external auditory canal (HP:0000413)1.91910437
131Increased CSF lactate (HP:0002490)1.91192703
132Decreased electroretinogram (ERG) amplitude (HP:0000654)1.90138026
133Congenital sensorineural hearing impairment (HP:0008527)1.89858120
134Abolished electroretinogram (ERG) (HP:0000550)1.89844299
135Albinism (HP:0001022)1.89327143
136Abnormality of the duodenum (HP:0002246)1.89227773
137Furrowed tongue (HP:0000221)1.88013012
138Elevated erythrocyte sedimentation rate (HP:0003565)1.87492062
139Ketosis (HP:0001946)1.87213395
140Rhabdomyosarcoma (HP:0002859)1.87192867
141Abnormal rod and cone electroretinograms (HP:0008323)1.87118443
142Aplasia/Hypoplasia of the tibia (HP:0005772)1.86976840
143Ectopic kidney (HP:0000086)1.86959675
144Aplasia/Hypoplasia involving the musculature (HP:0001460)1.86705050
145Respiratory failure (HP:0002878)1.86436112
146Duplicated collecting system (HP:0000081)1.85868413
147Abnormality of the metopic suture (HP:0005556)1.85093459
148Abnormality of the labia minora (HP:0012880)1.84788488
149Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.84568867
150Renal Fanconi syndrome (HP:0001994)1.83782889
151Sloping forehead (HP:0000340)1.82805487
152Abnormal lung lobation (HP:0002101)1.82262776
153Medulloblastoma (HP:0002885)1.82245556
154Intestinal atresia (HP:0011100)1.82187471
155Mitochondrial inheritance (HP:0001427)1.82179511
156Hypoplasia of the radius (HP:0002984)1.81665190
157Type 2 muscle fiber atrophy (HP:0003554)1.81301564
158Nephronophthisis (HP:0000090)1.80434767
159Hypoplasia of the pons (HP:0012110)1.80160176
160Lipid accumulation in hepatocytes (HP:0006561)1.79799176
161Megaloblastic anemia (HP:0001889)1.79442280
162Hypoglycemic seizures (HP:0002173)1.79294456
163Ependymoma (HP:0002888)1.79136100
164Abnormality of methionine metabolism (HP:0010901)1.79036557
165Basal cell carcinoma (HP:0002671)1.78315591
166Progressive inability to walk (HP:0002505)1.78275813
167Lethargy (HP:0001254)1.77782476
168Cutaneous melanoma (HP:0012056)1.77734639
169Hepatic necrosis (HP:0002605)1.77345810
170Muscle fibrillation (HP:0010546)1.76931394
171Abnormal protein glycosylation (HP:0012346)1.76910742
172Abnormal glycosylation (HP:0012345)1.76910742
173Abnormal protein N-linked glycosylation (HP:0012347)1.76910742
174Tinnitus (HP:0000360)1.76770412

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.43484058
2BUB15.10962220
3WEE13.87851116
4EIF2AK13.51296048
5CDC73.42341855
6TRIM283.09164513
7WNK32.93412421
8NME22.86293564
9VRK22.67594625
10STK162.65628217
11SRPK12.64731682
12ACVR1B2.43587423
13NUAK12.42039554
14VRK12.28523630
15NEK22.19446471
16MAP4K22.11526463
17TLK12.10776922
18EIF2AK32.09886784
19TESK22.07222188
20DYRK32.05841589
21BMPR1B2.04986072
22TSSK62.01326017
23NEK11.82465853
24TTK1.80326969
25PLK41.79583475
26PIM21.69034235
27PLK11.68088702
28PDK21.64224342
29TAF11.63532727
30RPS6KB21.59246045
31RPS6KA41.59136935
32BRSK21.58493476
33CDK71.57755992
34ERBB31.51959550
35PLK21.46079086
36CCNB11.43017237
37AURKB1.42935068
38GRK11.41754002
39ATR1.40630214
40MKNK11.40055960
41IRAK41.25714859
42ADRBK21.25300024
43CHEK21.24585614
44AURKA1.24340732
45CDK41.22884708
46EPHA21.19490185
47MKNK21.16388992
48STK101.16018339
49TNIK1.14733730
50BRSK11.12836193
51NME11.10828983
52MAP3K111.09126677
53PLK31.08937611
54MAP3K81.08280844
55MST41.07825300
56PASK1.07636657
57FER1.07321127
58MAP4K11.06643938
59BLK1.03110774
60MUSK1.03090721
61KDR1.01184137
62TESK11.00401856
63PAK40.98985829
64TGFBR10.97744652
65EEF2K0.97017423
66MAP3K100.91580332
67MAPKAPK30.89863798
68PIM10.89492501
69CHEK10.89316161
70CDK80.89157594
71STK40.88951619
72STK390.88595116
73INSRR0.88579065
74SCYL20.87641804
75MAP3K30.83166281
76ZAK0.82479451
77TAOK30.81988940
78LRRK20.80550519
79TEC0.78961216
80ZAP700.78897555
81EIF2AK20.75658718
82STK30.74946841
83STK240.74835410
84PINK10.74100713
85SIK30.73439013
86OXSR10.71940188
87BCKDK0.70184975
88CDK120.66100732
89CSNK2A10.65616018
90GRK60.65041710
91CDK20.63191106
92FLT30.62678917
93CSNK2A20.62559959
94PHKG10.60077451
95PHKG20.60077451
96PAK10.59678043
97PBK0.57942920
98CSNK1G10.57434789
99MAPK130.56631453
100BTK0.56604902
101BCR0.56027651
102RPS6KA50.53313133
103ATM0.53018796
104PRKCE0.52114787
105IRAK30.51829611
106TRPM70.51282856
107CLK10.50868180
108CSNK1G30.50381925
109DYRK20.48436848
110KIT0.48427582
111MAP2K30.48045692
112MAPKAPK50.47683688
113CSNK1A1L0.45765925
114CDK190.45513181
115MELK0.44701263
116BRAF0.43226018
117TAOK20.42988335
118FGFR20.41652731
119ERN10.41150908
120CDK60.40324293
121CDK10.39920817
122BMPR20.39578032
123MARK30.39487464
124AKT30.38841909
125ADRBK10.38574817
126PRKCI0.38342724
127PAK30.37923267
128YES10.37293651
129LIMK10.36582181
130WNK40.35456517
131AKT20.35025941
132STK38L0.34610160
133IKBKB0.34362649
134SYK0.33516965
135CSNK1G20.32570682
136TXK0.32332461
137IRAK10.32111792
138DAPK10.31942116
139ERBB40.31617629
140LYN0.31407264
141ILK0.31396063
142CSF1R0.31219403
143MAP3K120.30885822
144ABL20.29829313
145TBK10.29320491
146GRK70.29194457
147JAK30.27347159
148OBSCN0.27067923
149PKN10.27040968
150BRD40.26641421
151MAP2K10.25782198
152MAPKAPK20.22628215

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.04029139
2Mismatch repair_Homo sapiens_hsa034304.07382194
3Ribosome_Homo sapiens_hsa030103.86688583
4Proteasome_Homo sapiens_hsa030503.85830183
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.51893334
6RNA polymerase_Homo sapiens_hsa030203.28374175
7Spliceosome_Homo sapiens_hsa030403.28367742
8Base excision repair_Homo sapiens_hsa034103.13997394
9Homologous recombination_Homo sapiens_hsa034402.89528155
10RNA transport_Homo sapiens_hsa030132.86578651
11Nucleotide excision repair_Homo sapiens_hsa034202.74807845
12Pyrimidine metabolism_Homo sapiens_hsa002402.63537545
13Cell cycle_Homo sapiens_hsa041102.38118268
14One carbon pool by folate_Homo sapiens_hsa006702.37470350
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.26089334
16Maturity onset diabetes of the young_Homo sapiens_hsa049502.19356824
17Non-homologous end-joining_Homo sapiens_hsa034501.94721368
18Fanconi anemia pathway_Homo sapiens_hsa034601.93356148
19Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.93160513
20Propanoate metabolism_Homo sapiens_hsa006401.80818025
21RNA degradation_Homo sapiens_hsa030181.75079998
22Basal transcription factors_Homo sapiens_hsa030221.66464690
23Butanoate metabolism_Homo sapiens_hsa006501.60166423
24Sulfur metabolism_Homo sapiens_hsa009201.59546839
25Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.51748874
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.46456783
27mRNA surveillance pathway_Homo sapiens_hsa030151.41949916
28p53 signaling pathway_Homo sapiens_hsa041151.40337526
29Purine metabolism_Homo sapiens_hsa002301.32254322
30Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.32033256
31Fatty acid elongation_Homo sapiens_hsa000621.27407571
32Epstein-Barr virus infection_Homo sapiens_hsa051691.20158977
33Sulfur relay system_Homo sapiens_hsa041221.18591356
34Phototransduction_Homo sapiens_hsa047441.13979353
35Protein export_Homo sapiens_hsa030601.12704028
36Systemic lupus erythematosus_Homo sapiens_hsa053221.08830572
37Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.06869865
38Tryptophan metabolism_Homo sapiens_hsa003801.05879266
39Folate biosynthesis_Homo sapiens_hsa007901.03858656
40SNARE interactions in vesicular transport_Homo sapiens_hsa041301.03189384
41Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.01985848
42Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.99200542
43Pentose phosphate pathway_Homo sapiens_hsa000300.97012232
44Antigen processing and presentation_Homo sapiens_hsa046120.96749608
45Herpes simplex infection_Homo sapiens_hsa051680.96199974
46Cyanoamino acid metabolism_Homo sapiens_hsa004600.92376057
47Ether lipid metabolism_Homo sapiens_hsa005650.89144070
48Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.89141722
49Peroxisome_Homo sapiens_hsa041460.89126861
50Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.87111184
51Steroid biosynthesis_Homo sapiens_hsa001000.86812709
52Nitrogen metabolism_Homo sapiens_hsa009100.86408070
53Parkinsons disease_Homo sapiens_hsa050120.86237311
54Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.81822560
55Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.80692492
56Viral carcinogenesis_Homo sapiens_hsa052030.80256510
57Huntingtons disease_Homo sapiens_hsa050160.79458223
58Legionellosis_Homo sapiens_hsa051340.77895927
59Cysteine and methionine metabolism_Homo sapiens_hsa002700.77867192
60Primary immunodeficiency_Homo sapiens_hsa053400.76996378
61Drug metabolism - other enzymes_Homo sapiens_hsa009830.75475775
62Collecting duct acid secretion_Homo sapiens_hsa049660.74286027
63Vitamin B6 metabolism_Homo sapiens_hsa007500.72227207
64Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.71919367
65Oxidative phosphorylation_Homo sapiens_hsa001900.71792347
66Biosynthesis of amino acids_Homo sapiens_hsa012300.71321826
67alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.70325641
68Glycosaminoglycan degradation_Homo sapiens_hsa005310.69476701
69Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.67695287
70HTLV-I infection_Homo sapiens_hsa051660.64936988
71Linoleic acid metabolism_Homo sapiens_hsa005910.64562629
72N-Glycan biosynthesis_Homo sapiens_hsa005100.64229524
73Selenocompound metabolism_Homo sapiens_hsa004500.59124483
74Glutathione metabolism_Homo sapiens_hsa004800.58856359
75Oocyte meiosis_Homo sapiens_hsa041140.58840224
76Type I diabetes mellitus_Homo sapiens_hsa049400.54582475
77Thyroid cancer_Homo sapiens_hsa052160.53846229
78Circadian rhythm_Homo sapiens_hsa047100.52538924
79Apoptosis_Homo sapiens_hsa042100.51740466
80Pyruvate metabolism_Homo sapiens_hsa006200.51699934
81Shigellosis_Homo sapiens_hsa051310.51374646
82Fatty acid metabolism_Homo sapiens_hsa012120.51245384
83Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.50026621
84Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.49303262
85Primary bile acid biosynthesis_Homo sapiens_hsa001200.49232690
86Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.46580514
87Carbon metabolism_Homo sapiens_hsa012000.46253595
88Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.45792397
89Measles_Homo sapiens_hsa051620.44230964
90Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.43461479
91Lysine degradation_Homo sapiens_hsa003100.43063465
922-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.41735199
93NF-kappa B signaling pathway_Homo sapiens_hsa040640.41451158
94Steroid hormone biosynthesis_Homo sapiens_hsa001400.39005304
95Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.37633572
96Small cell lung cancer_Homo sapiens_hsa052220.36178775
97Fructose and mannose metabolism_Homo sapiens_hsa000510.34970482
98RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.34697337
99Hematopoietic cell lineage_Homo sapiens_hsa046400.34177809
100Galactose metabolism_Homo sapiens_hsa000520.33824011
101Hepatitis B_Homo sapiens_hsa051610.33752435
102Transcriptional misregulation in cancer_Homo sapiens_hsa052020.33657294
103beta-Alanine metabolism_Homo sapiens_hsa004100.33160222
104Sphingolipid metabolism_Homo sapiens_hsa006000.32756363
105Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.32677460
106Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.32036767
107Intestinal immune network for IgA production_Homo sapiens_hsa046720.31022733
108Bladder cancer_Homo sapiens_hsa052190.30873038
109Metabolic pathways_Homo sapiens_hsa011000.30747615
110Caffeine metabolism_Homo sapiens_hsa002320.30685307
111Alcoholism_Homo sapiens_hsa050340.29688539
112Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.29020452
113MicroRNAs in cancer_Homo sapiens_hsa052060.26168062
114Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.26109434
115Leishmaniasis_Homo sapiens_hsa051400.26022136
116Graft-versus-host disease_Homo sapiens_hsa053320.25089103
117Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.24092160
118Influenza A_Homo sapiens_hsa051640.24073773
119Notch signaling pathway_Homo sapiens_hsa043300.23676043
120Renin-angiotensin system_Homo sapiens_hsa046140.23377235
121Alzheimers disease_Homo sapiens_hsa050100.22816071
122Arachidonic acid metabolism_Homo sapiens_hsa005900.21682299
123Acute myeloid leukemia_Homo sapiens_hsa052210.21459752
124Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.21013725
125Mineral absorption_Homo sapiens_hsa049780.20938321
126Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.20618661
127Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.20442728
128Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.20135957
129NOD-like receptor signaling pathway_Homo sapiens_hsa046210.20050376
130Allograft rejection_Homo sapiens_hsa053300.19551514
131Vitamin digestion and absorption_Homo sapiens_hsa049770.18721131
132Fatty acid degradation_Homo sapiens_hsa000710.18560476
133Viral myocarditis_Homo sapiens_hsa054160.17830750
134Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.17590526
135Colorectal cancer_Homo sapiens_hsa052100.15927651
136TGF-beta signaling pathway_Homo sapiens_hsa043500.13394392
137Asthma_Homo sapiens_hsa053100.12797663
138Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.11590080
139HIF-1 signaling pathway_Homo sapiens_hsa040660.11363300
140Chronic myeloid leukemia_Homo sapiens_hsa052200.11270952
141Regulation of autophagy_Homo sapiens_hsa041400.10257470

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