EHBP1L1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1muscle filament sliding (GO:0030049)7.53090955
2actin-myosin filament sliding (GO:0033275)7.53090955
3sarcomere organization (GO:0045214)7.21067140
4plasma membrane repair (GO:0001778)6.46022236
5actin-mediated cell contraction (GO:0070252)6.18474288
6regulation of skeletal muscle contraction (GO:0014819)6.10546967
7cardiac myofibril assembly (GO:0055003)6.02048277
8myofibril assembly (GO:0030239)5.96443283
9negative regulation of potassium ion transmembrane transporter activity (GO:1901017)5.71947043
10positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)5.05389473
11actin filament-based movement (GO:0030048)5.00491637
12negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.99377532
13negative regulation of cell killing (GO:0031342)4.99377532
14negative regulation of potassium ion transmembrane transport (GO:1901380)4.73917658
15sarcoplasmic reticulum calcium ion transport (GO:0070296)4.71072295
16actomyosin structure organization (GO:0031032)4.68730861
17skeletal muscle contraction (GO:0003009)4.54497215
18cardiac muscle contraction (GO:0060048)4.49694409
19response to peptidoglycan (GO:0032494)4.48816619
20regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)4.44530248
21cardiac muscle cell development (GO:0055013)4.42989185
22antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.36903862
23detection of other organism (GO:0098543)4.34767448
24negative regulation of erythrocyte differentiation (GO:0045647)4.34311192
25striated muscle contraction (GO:0006941)4.34251771
26antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.33818667
27antigen processing and presentation of endogenous antigen (GO:0019883)4.28981397
28regulation of relaxation of muscle (GO:1901077)4.22147695
29detection of bacterium (GO:0016045)4.19425995
30cardiac cell development (GO:0055006)4.15420909
31neutrophil activation involved in immune response (GO:0002283)4.13421694
32macrophage activation involved in immune response (GO:0002281)4.11460367
33antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.04812107
34skeletal muscle adaptation (GO:0043501)3.98651015
35carnitine shuttle (GO:0006853)3.90622353
36regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.89629630
37regulation of gamma-delta T cell activation (GO:0046643)3.86408920
38regulation of actin filament-based movement (GO:1903115)3.84367701
39negative regulation of interleukin-12 production (GO:0032695)3.83225190
40detection of external biotic stimulus (GO:0098581)3.71522506
41cardiac muscle tissue morphogenesis (GO:0055008)3.71129447
42cellular extravasation (GO:0045123)3.67772147
43regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.63380233
44cardiac muscle hypertrophy (GO:0003300)3.61856934
45germinal center formation (GO:0002467)3.61332771
46striated muscle atrophy (GO:0014891)3.57257335
47response to muramyl dipeptide (GO:0032495)3.56427116
48regulation of cell communication by electrical coupling (GO:0010649)3.56230769
49detection of molecule of bacterial origin (GO:0032490)3.54935579
50regulation of striated muscle contraction (GO:0006942)3.53600145
51adult heart development (GO:0007512)3.53064703
52tricarboxylic acid cycle (GO:0006099)3.50475014
53positive regulation of myotube differentiation (GO:0010831)3.49786319
54striated muscle hypertrophy (GO:0014897)3.48638057
55regulation of sarcomere organization (GO:0060297)3.48319084
56leukocyte aggregation (GO:0070486)3.46983884
57muscle tissue morphogenesis (GO:0060415)3.46766274
58regulation of B cell receptor signaling pathway (GO:0050855)3.45872508
59fatty acid transmembrane transport (GO:1902001)3.45571282
60heart trabecula formation (GO:0060347)3.43258391
61regulation of interferon-beta biosynthetic process (GO:0045357)3.40688870
62regulation of gamma-delta T cell differentiation (GO:0045586)3.35726764
63muscle contraction (GO:0006936)3.30920134
64regulation of sequestering of triglyceride (GO:0010889)3.29404380
65response to stimulus involved in regulation of muscle adaptation (GO:0014874)3.26425494
66muscle hypertrophy (GO:0014896)3.26189583
67immunoglobulin mediated immune response (GO:0016064)3.26158341
68heart process (GO:0003015)3.25981308
69heart contraction (GO:0060047)3.25981308
70regulation of mast cell degranulation (GO:0043304)3.23661827
71regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.23570755
72detection of biotic stimulus (GO:0009595)3.23285931
73regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.22856866
74positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.15268045
75ventricular cardiac muscle tissue morphogenesis (GO:0055010)3.14798796
76striated muscle adaptation (GO:0014888)3.14659563
77cytidine catabolic process (GO:0006216)3.14329057
78cytidine deamination (GO:0009972)3.14329057
79cytidine metabolic process (GO:0046087)3.14329057
80negative regulation of lymphocyte mediated immunity (GO:0002707)3.12636284
81response to host defenses (GO:0052200)3.10689681
82response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.10689681
83response to host (GO:0075136)3.10689681
84response to host immune response (GO:0052572)3.09435004
85response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.09435004
86regulation of leukocyte degranulation (GO:0043300)3.09211017
87muscle system process (GO:0003012)3.09105012
88positive thymic T cell selection (GO:0045059)3.08341513
89regulation of p38MAPK cascade (GO:1900744)3.08307369
90regulation of myeloid leukocyte mediated immunity (GO:0002886)3.07104214
91pyrimidine ribonucleoside catabolic process (GO:0046133)3.06979376
92carnitine transmembrane transport (GO:1902603)3.05418594
93regulation of necroptotic process (GO:0060544)3.05384528
94negative regulation of T cell mediated immunity (GO:0002710)3.04398974
95regulation of dendritic cell antigen processing and presentation (GO:0002604)3.04040104
96positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.01403924
97regulation of the force of heart contraction (GO:0002026)3.00836225
98mannose metabolic process (GO:0006013)2.99897368
99striated muscle cell development (GO:0055002)2.99761435
100muscle atrophy (GO:0014889)2.98949480
101lipopolysaccharide-mediated signaling pathway (GO:0031663)2.98268795
102neutrophil activation (GO:0042119)2.97805479
103B cell receptor signaling pathway (GO:0050853)2.97796308
104regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.97361963
105muscle adaptation (GO:0043500)2.96783397
106ventricular cardiac muscle cell action potential (GO:0086005)2.95781205
107macrophage activation (GO:0042116)2.95581129
108respiratory burst (GO:0045730)2.95390853
109negative regulation of cardiac muscle tissue growth (GO:0055022)2.94809281
110negative regulation of heart growth (GO:0061117)2.94809281
111negative regulation of leukocyte mediated immunity (GO:0002704)2.93296823
112positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.92611846
113regulation of mast cell activation involved in immune response (GO:0033006)2.91507199
114bundle of His cell to Purkinje myocyte communication (GO:0086069)2.90477664
115negative regulation of cell size (GO:0045792)2.90110438
116granulocyte activation (GO:0036230)2.87250287
117positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.86715129
118positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.84578801
119myeloid cell activation involved in immune response (GO:0002275)2.84093244
120positive regulation by symbiont of host defense response (GO:0052509)2.82519308
121modulation by symbiont of host defense response (GO:0052031)2.82519308
122modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.82519308
123modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.82519308
124positive regulation by organism of defense response of other organism involved in symbiotic interact2.82519308
125modulation by symbiont of host immune response (GO:0052553)2.82519308
126NIK/NF-kappaB signaling (GO:0038061)2.82329973
127response to muscle activity (GO:0014850)2.82149018
128positive regulation of cellular amide metabolic process (GO:0034250)2.80647841
129response to inactivity (GO:0014854)2.80044970
130response to type I interferon (GO:0034340)2.78801982
131apoptotic cell clearance (GO:0043277)2.78399345
132microglial cell activation (GO:0001774)2.77051389
133regulation of T cell tolerance induction (GO:0002664)2.76841543
134cellular response to type I interferon (GO:0071357)2.76755372
135type I interferon signaling pathway (GO:0060337)2.76755372
136antigen processing and presentation via MHC class Ib (GO:0002475)2.75135129
137skeletal muscle tissue regeneration (GO:0043403)2.75043602
138regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.74654688
139creatine metabolic process (GO:0006600)2.74471792
140regulation of tolerance induction (GO:0002643)2.74238605
141positive regulation of Cdc42 GTPase activity (GO:0043089)2.74105227
142positive regulation of B cell differentiation (GO:0045579)2.73768105
143interferon-gamma-mediated signaling pathway (GO:0060333)2.73348126
144regulation of T-helper 2 cell differentiation (GO:0045628)2.72728209
145muscle fiber development (GO:0048747)2.72686767
146positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.72459885
147defense response to protozoan (GO:0042832)2.71619673
148carnitine transport (GO:0015879)2.70989300
149amino-acid betaine transport (GO:0015838)2.70989300
150positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.69864822
151vascular endothelial growth factor signaling pathway (GO:0038084)2.68700061
152negative regulation of muscle hypertrophy (GO:0014741)2.66936072
153production of molecular mediator involved in inflammatory response (GO:0002532)2.66703491
154regulation of muscle contraction (GO:0006937)2.66572511
155negative thymic T cell selection (GO:0045060)2.66522031
156regulation of acyl-CoA biosynthetic process (GO:0050812)2.63461604
157response to laminar fluid shear stress (GO:0034616)2.62977800
158negative regulation of cytokine production involved in immune response (GO:0002719)2.62413013
159T cell selection (GO:0045058)2.59919344
160cardiac muscle hypertrophy in response to stress (GO:0014898)2.59043032
161muscle hypertrophy in response to stress (GO:0003299)2.59043032
162cardiac muscle adaptation (GO:0014887)2.59043032
163positive regulation of gamma-delta T cell activation (GO:0046645)2.58939742
164T-helper 1 type immune response (GO:0042088)2.57957531
165thymic T cell selection (GO:0045061)2.56781721
166cell-substrate junction assembly (GO:0007044)2.56139138
167muscle cell development (GO:0055001)2.55699087
168skeletal muscle fiber development (GO:0048741)2.55500504
169negative regulation of potassium ion transport (GO:0043267)2.54335513
170positive regulation of cation channel activity (GO:2001259)2.54185360
171negative regulation of cardiac muscle hypertrophy (GO:0010614)2.53943727
172regulation of antigen processing and presentation (GO:0002577)2.53876430
173regulation of fatty acid oxidation (GO:0046320)2.53111423
174response to protozoan (GO:0001562)2.52938951
175positive regulation of mast cell activation (GO:0033005)2.52907696
176regulation of macrophage cytokine production (GO:0010935)2.52516864
177negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.52106895
178negative regulation of necroptotic process (GO:0060546)2.52056630
179membrane raft organization (GO:0031579)2.52035145
180response to interleukin-15 (GO:0070672)2.51809768
181negative regulation of innate immune response (GO:0045824)2.50378158
182regulation of B cell differentiation (GO:0045577)2.50219484
183negative regulation of nitric-oxide synthase activity (GO:0051001)2.49800845
184negative regulation of toll-like receptor signaling pathway (GO:0034122)2.49577781
185negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.49164097
186positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.49036901
187negative T cell selection (GO:0043383)2.48310557
188regulation of mast cell activation (GO:0033003)2.47089613
189regulation of regulated secretory pathway (GO:1903305)2.46458911
190negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.45770469
191leukocyte migration involved in inflammatory response (GO:0002523)2.45366496
192regulation of type I interferon-mediated signaling pathway (GO:0060338)2.44656776
193T cell migration (GO:0072678)2.44529970

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human4.63082431
2PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.93754524
3RARG_19884340_ChIP-ChIP_MEFs_Mouse3.07446585
4NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.03074762
5IRF8_22096565_ChIP-ChIP_GC-B_Human2.60827277
6STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.60379329
7TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.59825291
8TBX20_22328084_ChIP-Seq_HEART_Mouse2.44805954
9TBX20_22080862_ChIP-Seq_HEART_Mouse2.44805954
10IRF8_21731497_ChIP-ChIP_J774_Mouse2.25881389
11TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.25557570
12VDR_21846776_ChIP-Seq_THP-1_Human2.20747935
13THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.19627572
14* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.17145447
15MYB_21317192_ChIP-Seq_ERMYB_Mouse2.16597440
16IRF8_27001747_Chip-Seq_BMDM_Mouse2.16536618
17* ELK3_25401928_ChIP-Seq_HUVEC_Human2.16431849
18NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.16082497
19EP300_21415370_ChIP-Seq_HL-1_Mouse2.06408678
20TRIM28_21343339_ChIP-Seq_HEK293_Human2.04786626
21MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.01583783
22* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.01130741
23* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.98394069
24VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.96427099
25SPI1_23127762_ChIP-Seq_K562_Human1.95274048
26RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.94851861
27* KDM2B_26808549_Chip-Seq_DND41_Human1.90054794
28TCF7_22412390_ChIP-Seq_EML_Mouse1.89833387
29* MAF_26560356_Chip-Seq_TH1_Human1.86452184
30Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.85881399
31NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.82729648
32* SPI1_23547873_ChIP-Seq_NB4_Human1.82724555
33* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.79500138
34* GATA1_19941826_ChIP-Seq_K562_Human1.78254092
35RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.75698553
36CLOCK_20551151_ChIP-Seq_293T_Human1.75109605
37SCL_19346495_ChIP-Seq_HPC-7_Human1.69643149
38VDR_24763502_ChIP-Seq_THP-1_Human1.69632408
39EGR1_19374776_ChIP-ChIP_THP-1_Human1.62241620
40GATA2_21666600_ChIP-Seq_HMVEC_Human1.61383746
41IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.60593332
42EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.60291250
43* GATA1_19941827_ChIP-Seq_MEL_Mouse1.59845636
44STAT6_21828071_ChIP-Seq_BEAS2B_Human1.59199744
45MYC_22102868_ChIP-Seq_BL_Human1.58772816
46* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.58031447
47TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.57118647
48GATA1_22025678_ChIP-Seq_K562_Human1.54042199
49TP63_17297297_ChIP-ChIP_HaCaT_Human1.53609271
50RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.51174638
51* UTX_26944678_Chip-Seq_JUKART_Human1.49779653
52* MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.49773080
53IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.49617239
54MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.48025134
55RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.47634940
56* GATA2_19941826_ChIP-Seq_K562_Human1.47385508
57ZNF263_19887448_ChIP-Seq_K562_Human1.45930997
58* MYB_26560356_Chip-Seq_TH1_Human1.45673180
59* LXR_22292898_ChIP-Seq_THP-1_Human1.45491828
60* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.44439556
61CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.43650440
62ESR1_20079471_ChIP-ChIP_T-47D_Human1.42784790
63* KDM2B_26808549_Chip-Seq_JURKAT_Human1.41245823
64* RUNX1_22412390_ChIP-Seq_EML_Mouse1.34816992
65* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.34222950
66CDX2_19796622_ChIP-Seq_MESCs_Mouse1.33938910
67* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.32582107
68* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.30760123
69FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.30068560
70NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.29780900
71HIF1A_21447827_ChIP-Seq_MCF-7_Human1.29065981
72ATF3_27146783_Chip-Seq_COLON_Human1.28731574
73VDR_24787735_ChIP-Seq_THP-1_Human1.28212780
74GATA4_21415370_ChIP-Seq_HL-1_Mouse1.27471115
75SMAD_19615063_ChIP-ChIP_OVARY_Human1.26702882
76PPAR_26484153_Chip-Seq_NCI-H1993_Human1.26529360
77ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.25752189
78KDM2B_26808549_Chip-Seq_K562_Human1.25735362
79KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.25589373
80CTCF_27219007_Chip-Seq_ERYTHROID_Human1.24684702
81* RACK7_27058665_Chip-Seq_MCF-7_Human1.22946937
82PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.22471070
83* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.21527369
84STAT4_19710469_ChIP-ChIP_TH1__Mouse1.21217567
85PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.20951622
86CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.20335713
87GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.18861682
88SPI1_20517297_ChIP-Seq_HL60_Human1.18332685
89* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.17605550
90LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.16141909
91RUNX_20019798_ChIP-Seq_JUKART_Human1.15430044
92MYB_26560356_Chip-Seq_TH2_Human1.15413358
93ESR2_21235772_ChIP-Seq_MCF-7_Human1.14856530
94NCOR1_26117541_ChIP-Seq_K562_Human1.14224839
95GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.12056663
96STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.11896678
97* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.11514777
98CJUN_26792858_Chip-Seq_BT549_Human1.09931847
99NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.09892692
100FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.09748855
101JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.09725020
102ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.09006227
103ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.08915589
104LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.07795196
105TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.07504872
106SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.06779061
107SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.04483543
108SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.04483543
109TP53_22127205_ChIP-Seq_IMR90_Human1.04331686
110JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.04104105
111SA1_27219007_Chip-Seq_ERYTHROID_Human1.04090782
112* MAF_26560356_Chip-Seq_TH2_Human1.03666784
113GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.03352165
114BCOR_27268052_Chip-Seq_Bcells_Human1.02757682
115PU_27001747_Chip-Seq_BMDM_Mouse1.02485462
116SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01899837
117* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.01641861
118P63_26484246_Chip-Seq_KERATINOCYTES_Human1.01561193
119* SMC1_22415368_ChIP-Seq_MEFs_Mouse1.01538225
120* PU.1_20513432_ChIP-Seq_Bcells_Mouse1.01052987
121* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.00944234
122* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.00589953
123* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.00440757
124GATA3_27048872_Chip-Seq_THYMUS_Human1.00151801
125PPARA_22158963_ChIP-Seq_LIVER_Mouse0.96788938
126CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.95048970
127* BCL6_27268052_Chip-Seq_Bcells_Human0.94873768

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis4.51315923
2MP0000751_myopathy4.36319390
3MP0003646_muscle_fatigue4.07675198
4MP0000749_muscle_degeneration4.03541602
5MP0004084_abnormal_cardiac_muscle3.86461729
6MP0004036_abnormal_muscle_relaxation3.12001962
7MP0003724_increased_susceptibility_to3.02314935
8MP0005451_abnormal_body_composition3.00301817
9MP0000750_abnormal_muscle_regeneration2.89337264
10MP0004087_abnormal_muscle_fiber2.87155888
11MP0005330_cardiomyopathy2.81742477
12MP0004215_abnormal_myocardial_fiber2.77866245
13MP0008438_abnormal_cutaneous_collagen2.68951968
14MP0004510_myositis2.59968304
15MP0002106_abnormal_muscle_physiology2.48316768
16MP0004145_abnormal_muscle_electrophysio2.37823732
17MP0004130_abnormal_muscle_cell2.35326484
18MP0002972_abnormal_cardiac_muscle2.24088848
19MP0005620_abnormal_muscle_contractility2.20541662
20MP0000759_abnormal_skeletal_muscle2.18970882
21MP0000747_muscle_weakness2.17728378
22MP0010630_abnormal_cardiac_muscle2.14895496
23MP0008775_abnormal_heart_ventricle2.13037429
24MP0003705_abnormal_hypodermis_morpholog2.09654800
25MP0008260_abnormal_autophagy2.08194609
26MP0003828_pulmonary_edema2.05257074
27MP0002269_muscular_atrophy2.05086095
28MP0006082_CNS_inflammation2.04446982
29MP0005369_muscle_phenotype1.97399191
30MP0002723_abnormal_immune_serum1.96883250
31MP0003172_abnormal_lysosome_physiology1.94941843
32MP0002420_abnormal_adaptive_immunity1.90836228
33MP0005671_abnormal_response_to1.90298306
34MP0005385_cardiovascular_system_phenoty1.89822648
35MP0001544_abnormal_cardiovascular_syste1.89822648
36MP0003279_aneurysm1.88235372
37MP0003763_abnormal_thymus_physiology1.86956305
38MP0004947_skin_inflammation1.84367848
39MP0003566_abnormal_cell_adhesion1.81788964
40MP0003303_peritoneal_inflammation1.78166205
41MP0004484_altered_response_of1.67023012
42MP0000733_abnormal_muscle_development1.65535420
43MP0010155_abnormal_intestine_physiology1.61294407
44MP0000343_altered_response_to1.59354516
45MP0005275_abnormal_skin_tensile1.54002043
46MP0002398_abnormal_bone_marrow1.48459432
47MP0003656_abnormal_erythrocyte_physiolo1.47844016
48MP0000858_altered_metastatic_potential1.46511465
49MP0003221_abnormal_cardiomyocyte_apopto1.44986859
50MP0006138_congestive_heart_failure1.44594773
51MP0000716_abnormal_immune_system1.44096404
52MP0005666_abnormal_adipose_tissue1.43769604
53MP0009333_abnormal_splenocyte_physiolog1.43033834
54MP0001845_abnormal_inflammatory_respons1.41438055
55MP0005670_abnormal_white_adipose1.40350887
56MP0009840_abnormal_foam_cell1.39635365
57MP0003137_abnormal_impulse_conducting1.39224941
58MP0003950_abnormal_plasma_membrane1.38472248
59MP0002396_abnormal_hematopoietic_system1.32934594
60MP0002332_abnormal_exercise_endurance1.30064455
61MP0004185_abnormal_adipocyte_glucose1.29939451
62MP0004233_abnormal_muscle_weight1.25036499
63MP0008469_abnormal_protein_level1.22481677
64MP0001958_emphysema1.21671787
65MP0003436_decreased_susceptibility_to1.21496478
66MP0002722_abnormal_immune_system1.20853019
67MP0005058_abnormal_lysosome_morphology1.20600085
68MP0000689_abnormal_spleen_morphology1.18746208
69MP0002429_abnormal_blood_cell1.18221431
70MP0003075_altered_response_to1.15881907
71MP0003453_abnormal_keratinocyte_physiol1.14489702
72MP0009278_abnormal_bone_marrow1.12721219
73MP0001851_eye_inflammation1.12394193
74MP0000767_abnormal_smooth_muscle1.10680454
75MP0004883_abnormal_blood_vessel1.10325281
76MP0005310_abnormal_salivary_gland1.09580142
77MP0005375_adipose_tissue_phenotype1.09300804
78MP0003300_gastrointestinal_ulcer1.08449618
79MP0001835_abnormal_antigen_presentation1.07212153
80MP0000465_gastrointestinal_hemorrhage1.06887183
81MP0000685_abnormal_immune_system1.06380632
82MP0003866_abnormal_defecation1.06059892
83MP0005166_decreased_susceptibility_to1.05601424
84MP0005164_abnormal_response_to1.04832828
85MP0009764_decreased_sensitivity_to1.02770088
86MP0000703_abnormal_thymus_morphology1.02277844
87MP0001873_stomach_inflammation1.02241973
88MP0004085_abnormal_heartbeat1.02161162
89MP0003045_fibrosis0.98626574
90MP0000266_abnormal_heart_morphology0.98589710
91MP0005623_abnormal_meninges_morphology0.98578793
92MP0003091_abnormal_cell_migration0.96475543
93MP0002132_abnormal_respiratory_system0.96240786
94MP0002108_abnormal_muscle_morphology0.95320822
95MP0006036_abnormal_mitochondrial_physio0.95235787
96MP0004381_abnormal_hair_follicle0.94336446
97MP0002419_abnormal_innate_immunity0.93640695
98MP0005387_immune_system_phenotype0.91683742
99MP0001790_abnormal_immune_system0.91683742
100MP0000604_amyloidosis0.91469011
101MP0001879_abnormal_lymphatic_vessel0.90877453
102MP0010368_abnormal_lymphatic_system0.90291562
103MP0001849_ear_inflammation0.89286279
104MP0002971_abnormal_brown_adipose0.88615697
105MP0003183_abnormal_peptide_metabolism0.88003298
106MP0002128_abnormal_blood_circulation0.87604965
107MP0001533_abnormal_skeleton_physiology0.87072502
108MP0005390_skeleton_phenotype0.84893565
109MP0005023_abnormal_wound_healing0.84449032
110MP0001853_heart_inflammation0.83493278
111MP0004147_increased_porphyrin_level0.82930879
112MP0009785_altered_susceptibility_to0.82079873
113MP0004808_abnormal_hematopoietic_stem0.81491829
114MP0002933_joint_inflammation0.81139953
115MP0003690_abnormal_glial_cell0.80438106
116MP0002127_abnormal_cardiovascular_syste0.79983464
117MP0003795_abnormal_bone_structure0.79475879
118MP0010352_gastrointestinal_tract_polyps0.79468572
119MP0005025_abnormal_response_to0.79276399
120MP0002452_abnormal_antigen_presenting0.79190275
121MP0005165_increased_susceptibility_to0.78150881
122MP0005397_hematopoietic_system_phenotyp0.77560525
123MP0001545_abnormal_hematopoietic_system0.77560525
124MP0005000_abnormal_immune_tolerance0.77076856
125MP0005076_abnormal_cell_differentiation0.76040591
126MP0005464_abnormal_platelet_physiology0.75249134
127MP0001800_abnormal_humoral_immune0.74829384
128MP0003567_abnormal_fetal_cardiomyocyte0.74776559
129MP0003448_altered_tumor_morphology0.74591568
130MP0002166_altered_tumor_susceptibility0.74479618
131MP0002877_abnormal_melanocyte_morpholog0.74457997
132MP0005503_abnormal_tendon_morphology0.73731998
133MP0000013_abnormal_adipose_tissue0.73460302
134MP0002148_abnormal_hypersensitivity_rea0.71115525
135MP0000249_abnormal_blood_vessel0.68743411
136MP0000003_abnormal_adipose_tissue0.67622829
137MP0002405_respiratory_system_inflammati0.66898707
138MP0004272_abnormal_basement_membrane0.65741073
139MP0002998_abnormal_bone_remodeling0.64326186
140MP0001819_abnormal_immune_cell0.62459538
141MP0003191_abnormal_cellular_cholesterol0.62392397
142MP0009115_abnormal_fat_cell0.62215193

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)5.62574905
2Exercise-induced muscle cramps (HP:0003710)5.52081472
3Muscle fiber splitting (HP:0003555)5.49509496
4Type 1 muscle fiber predominance (HP:0003803)5.42084924
5Exercise-induced myalgia (HP:0003738)5.37578432
6Calf muscle hypertrophy (HP:0008981)5.19203533
7Muscle fiber inclusion bodies (HP:0100299)5.16213047
8Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)5.13835371
9Muscle hypertrophy of the lower extremities (HP:0008968)4.97523491
10Increased connective tissue (HP:0009025)4.97069440
11Hyporeflexia of lower limbs (HP:0002600)4.86470996
12Ventricular tachycardia (HP:0004756)4.57526179
13Abnormality of the calf musculature (HP:0001430)4.54346207
14Nemaline bodies (HP:0003798)4.42364793
15Abnormality of the left ventricular outflow tract (HP:0011103)4.32134296
16Subaortic stenosis (HP:0001682)4.32134296
17Difficulty running (HP:0009046)4.29774211
18EMG: myopathic abnormalities (HP:0003458)4.23198353
19Recurrent bacterial skin infections (HP:0005406)4.20134208
20Asymmetric septal hypertrophy (HP:0001670)4.05465774
21Abnormality of macrophages (HP:0004311)3.96422049
22Lipoatrophy (HP:0100578)3.96209651
23Myoglobinuria (HP:0002913)3.89314402
24Difficulty climbing stairs (HP:0003551)3.86358839
25Distal arthrogryposis (HP:0005684)3.68638429
26Atrial fibrillation (HP:0005110)3.67440722
27Right ventricular cardiomyopathy (HP:0011663)3.49971734
28Myositis (HP:0100614)3.48153079
29Primary atrial arrhythmia (HP:0001692)3.43150249
30Round ear (HP:0100830)3.41159418
31Abnormality of skeletal muscle fiber size (HP:0012084)3.35414211
32Recurrent gram-negative bacterial infections (HP:0005420)3.34790713
33Rhabdomyolysis (HP:0003201)3.32933288
34Supraventricular tachycardia (HP:0004755)3.28086695
35Ulnar deviation of the wrist (HP:0003049)3.27467291
36Supraventricular arrhythmia (HP:0005115)3.25652102
37Increased variability in muscle fiber diameter (HP:0003557)3.23862944
38Orchitis (HP:0100796)3.17870514
39Dilated cardiomyopathy (HP:0001644)3.12378729
40Myotonia (HP:0002486)3.10657394
41Distal lower limb amyotrophy (HP:0008944)3.10208743
42Myopathic facies (HP:0002058)3.00900983
43Gastrointestinal infarctions (HP:0005244)2.97203967
44Mildly elevated creatine phosphokinase (HP:0008180)2.95456084
45Spontaneous hematomas (HP:0007420)2.91765021
46Recurrent fungal infections (HP:0002841)2.89125793
47Gingivitis (HP:0000230)2.87498039
48Distal lower limb muscle weakness (HP:0009053)2.87286594
49Frequent falls (HP:0002359)2.85893177
50Mediastinal lymphadenopathy (HP:0100721)2.85488873
51Increased IgE level (HP:0003212)2.82004635
52Neck muscle weakness (HP:0000467)2.80583399
53Retrobulbar optic neuritis (HP:0100654)2.80335598
54Optic neuritis (HP:0100653)2.80335598
55Cellulitis (HP:0100658)2.80118156
56Facial diplegia (HP:0001349)2.79534475
57Bundle branch block (HP:0011710)2.74289821
58Recurrent skin infections (HP:0001581)2.74255266
59Chronic obstructive pulmonary disease (HP:0006510)2.70278248
60Obstructive lung disease (HP:0006536)2.70278248
61Muscle stiffness (HP:0003552)2.70269696
62Scapular winging (HP:0003691)2.65635227
63Elevated erythrocyte sedimentation rate (HP:0003565)2.64694209
64Cerebral aneurysm (HP:0004944)2.61784105
65Meningitis (HP:0001287)2.61117383
66Premature rupture of membranes (HP:0001788)2.60595787
67Colitis (HP:0002583)2.55274695
68Abnormal delayed hypersensitivity skin test (HP:0002963)2.54868943
69Ventricular arrhythmia (HP:0004308)2.51070757
70Spinal rigidity (HP:0003306)2.51062388
71Chronic mucocutaneous candidiasis (HP:0002728)2.50716207
72Recurrent cutaneous fungal infections (HP:0011370)2.50716207
73Syncope (HP:0001279)2.49922275
74Generalized muscle weakness (HP:0003324)2.45148593
75Protrusio acetabuli (HP:0003179)2.44915650
76Prolonged QT interval (HP:0001657)2.44641541
77Centrally nucleated skeletal muscle fibers (HP:0003687)2.42430369
78Lower limb amyotrophy (HP:0007210)2.41653369
79Palpitations (HP:0001962)2.40030021
80Abnormality of glycolipid metabolism (HP:0010969)2.39542836
81Abnormality of liposaccharide metabolism (HP:0010968)2.39542836
82Abnormality of glycosphingolipid metabolism (HP:0004343)2.39542836
83Recurrent viral infections (HP:0004429)2.38999357
84Chest pain (HP:0100749)2.38315627
85Slender build (HP:0001533)2.37215567
86Inflammation of the large intestine (HP:0002037)2.37205586
87Gastrointestinal inflammation (HP:0004386)2.35701315
88Abnormal atrioventricular conduction (HP:0005150)2.34267536
89Prolonged bleeding time (HP:0003010)2.34029373
90Vasculitis (HP:0002633)2.32289024
91Urticaria (HP:0001025)2.32060110
92Stomatitis (HP:0010280)2.31356368
93Limb-girdle muscle atrophy (HP:0003797)2.31180823
94Areflexia of lower limbs (HP:0002522)2.29577781
95Increased density of long bones (HP:0006392)2.28260753
96Calcaneovalgus deformity (HP:0001848)2.27850802
97Heart block (HP:0012722)2.26403114
98Gowers sign (HP:0003391)2.21756321
99Pustule (HP:0200039)2.21741499
100Amyloidosis (HP:0011034)2.21480193
101Atrioventricular block (HP:0001678)2.21442392
102Keratoconjunctivitis sicca (HP:0001097)2.18539016
103Hypoplastic ischia (HP:0003175)2.13538369
104Malignant hyperthermia (HP:0002047)2.13161836
105Increased cerebral lipofuscin (HP:0011813)2.12969071
106EMG: neuropathic changes (HP:0003445)2.11200265
107Increased serum ferritin (HP:0003281)2.10698650
108Epistaxis (HP:0000421)2.10686194
109Malnutrition (HP:0004395)2.10253154
110Dysostosis multiplex (HP:0000943)2.07877237
111Deformed tarsal bones (HP:0008119)2.07295423
112Systemic lupus erythematosus (HP:0002725)2.07091382
113Broad metatarsal (HP:0001783)2.06132943
114Encephalitis (HP:0002383)2.05308707
115Osteomyelitis (HP:0002754)2.05129589
116Muscular dystrophy (HP:0003560)2.04621269
117Aortic aneurysm (HP:0004942)2.04040616
118Abnormality of the neuromuscular junction (HP:0003398)2.03291139
119Fatigable weakness (HP:0003473)2.03291139
120Hemoptysis (HP:0002105)2.02156139
121Pulmonary infiltrates (HP:0002113)1.97859381
122Recurrent abscess formation (HP:0002722)1.96850231
123Aortic dissection (HP:0002647)1.95324005
124Hip contracture (HP:0003273)1.95199283
125Absent phalangeal crease (HP:0006109)1.94613036
126Fatigue (HP:0012378)1.93805274
127Bulbar palsy (HP:0001283)1.93146784
128Gingival bleeding (HP:0000225)1.91394301
129Arterial thrombosis (HP:0004420)1.91257272
130Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.90996856
131Keratoconjunctivitis (HP:0001096)1.89177493
132Ankle contracture (HP:0006466)1.88822803
133Gastrointestinal stroma tumor (HP:0100723)1.88496365
134Loss of speech (HP:0002371)1.86848446
135Interstitial pulmonary disease (HP:0006530)1.86198034
136Abnormality of iron homeostasis (HP:0011031)1.84172806
137Eczematoid dermatitis (HP:0000976)1.83943542
138Wrist flexion contracture (HP:0001239)1.83692164
139Abnormality of the calcaneus (HP:0008364)1.83409275
140Abnormality of the fingertips (HP:0001211)1.83348631
141Testicular atrophy (HP:0000029)1.83336865
142Cholelithiasis (HP:0001081)1.81164276
143Spondylolisthesis (HP:0003302)1.80403398
144Restrictive lung disease (HP:0002091)1.79083455
145Abnormality of the peritoneum (HP:0002585)1.78225417
146Hypochromic anemia (HP:0001931)1.76967319
147Emphysema (HP:0002097)1.75660463
148Abnormality of the ischium (HP:0003174)1.75561467
149Weak cry (HP:0001612)1.75384543
150T lymphocytopenia (HP:0005403)1.74918588
151Reticulocytosis (HP:0001923)1.74779036
152Broad face (HP:0000283)1.74011808
153Easy fatigability (HP:0003388)1.73824852
154Segmental peripheral demyelination/remyelination (HP:0003481)1.73447538
155Proximal amyotrophy (HP:0007126)1.72641092
156Obstructive sleep apnea (HP:0002870)1.72339096
157Thin bony cortex (HP:0002753)1.72084463
158Dilatation of the ascending aorta (HP:0005111)1.71989113
159Myocardial infarction (HP:0001658)1.71772864
160Abnormality of the endocardium (HP:0004306)1.71351317
161Peritonitis (HP:0002586)1.70820599
162Limb-girdle muscle weakness (HP:0003325)1.69689099
163Abnormality of the foot musculature (HP:0001436)1.68824807
164Conjunctival hamartoma (HP:0100780)1.67132153
165Polycythemia (HP:0001901)1.66140725
166Sudden cardiac death (HP:0001645)1.64451403
167Rimmed vacuoles (HP:0003805)1.64090009
168Axonal loss (HP:0003447)1.63678910
169Abnormal EKG (HP:0003115)1.63622917
170Foot dorsiflexor weakness (HP:0009027)1.63224403

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN6.24484701
2OBSCN4.37790710
3TRIB34.05523638
4PRPF4B3.42274602
5PKN23.26008468
6DMPK2.69972018
7PHKG22.34863274
8PHKG12.34863274
9MYLK2.17022593
10MAP3K132.05769710
11MAP2K31.91275363
12PDK31.84662012
13PDK41.84662012
14PIK3CA1.83989073
15PIK3CG1.78756220
16TRPM71.74588174
17ERN11.65569403
18LMTK21.60015899
19TGFBR21.48744249
20MAP4K11.47647210
21TNK21.47330226
22MAP3K101.43340337
23RIPK11.37137889
24FES1.36578656
25TBK11.33572022
26GRK61.29650810
27TIE11.29436780
28FGR1.28547749
29TAOK21.27873214
30MAP3K11.27806632
31STK241.26753266
32TYK21.25795451
33SMG11.23607105
34EPHB11.19080870
35MARK21.18598196
36PDK21.17524420
37FGFR41.14904631
38KSR21.14084440
39EEF2K1.12583487
40CAMK1D1.11785635
41MUSK1.11649296
42JAK11.10000147
43ILK1.08925973
44PTK61.06323710
45MAPK121.04891748
46CDK121.03461520
47NEK91.03187922
48PTK2B1.01455851
49STK40.98342420
50PRKD20.97676973
51LRRK20.96343669
52KIT0.95416436
53JAK30.94618880
54BLK0.94107131
55SIK30.93966862
56MAP3K30.93469279
57MAP3K70.92873560
58MAP3K60.91519750
59MAPKAPK30.90922209
60NME20.89767380
61CAMK1G0.89304070
62MAPK70.88063403
63ZAK0.85497387
64PRKAA20.83906687
65PDGFRA0.82677762
66FLT30.82276283
67STK100.82253908
68PRKD10.81472652
69SIK10.79913146
70NEK10.79849700
71LYN0.79183864
72CSF1R0.79005173
73BMX0.77741434
74LCK0.75225556
75HCK0.74889685
76DAPK30.74713620
77KDR0.71946790
78IRAK20.71570635
79FGFR30.70879769
80TXK0.68519110
81ROCK10.66988121
82CSK0.66587974
83MATK0.66164424
84HIPK20.65265467
85ZAP700.65031161
86GRK70.63486972
87PAK20.62411394
88MOS0.62095672
89MAP3K50.61130341
90IRAK10.60701912
91MST1R0.58141364
92MAP3K140.57501902
93TESK10.57116015
94PRKAA10.56164233
95RIPK40.55490266
96SGK30.55257269
97ITK0.55207945
98RPS6KC10.53943904
99RPS6KL10.53943904
100IKBKB0.53632076
101RPS6KA60.53174416
102CDC42BPA0.52841412
103YES10.52243487
104TAOK10.51590323
105MAP3K110.50898810
106PDPK10.50775361
107BMPR20.49484263
108RPS6KA40.48521172
109PAK40.47989100
110SYK0.47902287
111MAPKAPK20.46875764
112JAK20.46760244
113MTOR0.46515762
114PRKG20.46385667
115MAP3K20.45987599
116DYRK1B0.45604616
117IRAK30.44933459
118RET0.44595415
119BCKDK0.44456159
120CDK40.43824643
121IKBKE0.43615179
122PDK10.43142851
123TESK20.42676609
124MARK30.42565264
125DDR20.42539484
126ICK0.40840237
127PIM20.40833111
128MAP2K60.40496620
129CDK60.40041078
130MAP3K80.39942869
131FYN0.39364230
132RPS6KA20.39076947
133NME10.38833027
134IRAK40.38435260
135MAPK110.38015854
136SIK20.37529104
137BTK0.36881966
138STK30.35937829
139AKT20.34505105
140MAP2K10.33855962

Predicted pathways (KEGG)

RankGene SetZ-score
1Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.75204571
2Dilated cardiomyopathy_Homo sapiens_hsa054143.58163561
3Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.51295339
4Cardiac muscle contraction_Homo sapiens_hsa042602.71245165
5Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.49076891
6Viral myocarditis_Homo sapiens_hsa054162.44496132
72-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.05990174
8Leishmaniasis_Homo sapiens_hsa051401.78334941
9Focal adhesion_Homo sapiens_hsa045101.70302265
10Allograft rejection_Homo sapiens_hsa053301.68440070
11Osteoclast differentiation_Homo sapiens_hsa043801.67401079
12Graft-versus-host disease_Homo sapiens_hsa053321.62644995
13Adipocytokine signaling pathway_Homo sapiens_hsa049201.53673151
14Autoimmune thyroid disease_Homo sapiens_hsa053201.51719455
15Insulin resistance_Homo sapiens_hsa049311.50051829
16Leukocyte transendothelial migration_Homo sapiens_hsa046701.41353281
17Malaria_Homo sapiens_hsa051441.39939102
18B cell receptor signaling pathway_Homo sapiens_hsa046621.36776945
19HIF-1 signaling pathway_Homo sapiens_hsa040661.35131968
20Toxoplasmosis_Homo sapiens_hsa051451.35086972
21T cell receptor signaling pathway_Homo sapiens_hsa046601.33830971
22ECM-receptor interaction_Homo sapiens_hsa045121.32599242
23Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.32048308
24Carbon metabolism_Homo sapiens_hsa012001.31732438
25Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.26794401
26Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.26141206
27Amoebiasis_Homo sapiens_hsa051461.26084562
28Platelet activation_Homo sapiens_hsa046111.25268325
29Primary immunodeficiency_Homo sapiens_hsa053401.25026342
30AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.23917694
31RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.22247641
32Fatty acid degradation_Homo sapiens_hsa000711.21105808
33Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.19961166
34Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.19652608
35Insulin signaling pathway_Homo sapiens_hsa049101.19130193
36Propanoate metabolism_Homo sapiens_hsa006401.18624310
37Chronic myeloid leukemia_Homo sapiens_hsa052201.13236873
38Herpes simplex infection_Homo sapiens_hsa051681.12004706
39Salmonella infection_Homo sapiens_hsa051321.11228583
40Asthma_Homo sapiens_hsa053101.09427797
41Hepatitis C_Homo sapiens_hsa051601.08932805
42Toll-like receptor signaling pathway_Homo sapiens_hsa046201.04981782
43Parkinsons disease_Homo sapiens_hsa050121.04427803
44Staphylococcus aureus infection_Homo sapiens_hsa051501.03833271
45Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.03793411
46Proteoglycans in cancer_Homo sapiens_hsa052051.03683475
47Type I diabetes mellitus_Homo sapiens_hsa049401.03607252
48Tuberculosis_Homo sapiens_hsa051521.00793622
49Legionellosis_Homo sapiens_hsa051341.00699350
50Notch signaling pathway_Homo sapiens_hsa043300.99154466
51Small cell lung cancer_Homo sapiens_hsa052220.98601462
52Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.97870890
53Regulation of actin cytoskeleton_Homo sapiens_hsa048100.97246607
54African trypanosomiasis_Homo sapiens_hsa051430.96843070
55Starch and sucrose metabolism_Homo sapiens_hsa005000.96419404
56GnRH signaling pathway_Homo sapiens_hsa049120.96138543
57Apoptosis_Homo sapiens_hsa042100.94994634
58Pertussis_Homo sapiens_hsa051330.94501130
59Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.94382438
60Acute myeloid leukemia_Homo sapiens_hsa052210.93837858
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.92937095
62AMPK signaling pathway_Homo sapiens_hsa041520.92246260
63Glucagon signaling pathway_Homo sapiens_hsa049220.91825327
64NF-kappa B signaling pathway_Homo sapiens_hsa040640.91187029
65cGMP-PKG signaling pathway_Homo sapiens_hsa040220.90583960
66Prolactin signaling pathway_Homo sapiens_hsa049170.89923774
67Measles_Homo sapiens_hsa051620.89335852
68Hematopoietic cell lineage_Homo sapiens_hsa046400.85683379
69Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.85363816
70TNF signaling pathway_Homo sapiens_hsa046680.84924762
71VEGF signaling pathway_Homo sapiens_hsa043700.84878073
72Alzheimers disease_Homo sapiens_hsa050100.83549853
73Central carbon metabolism in cancer_Homo sapiens_hsa052300.83380704
74Fatty acid metabolism_Homo sapiens_hsa012120.80922201
75Rheumatoid arthritis_Homo sapiens_hsa053230.80556082
76Adherens junction_Homo sapiens_hsa045200.80450496
77Jak-STAT signaling pathway_Homo sapiens_hsa046300.79763475
78Endometrial cancer_Homo sapiens_hsa052130.77596282
79Other glycan degradation_Homo sapiens_hsa005110.77476124
80Shigellosis_Homo sapiens_hsa051310.77196371
81Phospholipase D signaling pathway_Homo sapiens_hsa040720.76910581
82PPAR signaling pathway_Homo sapiens_hsa033200.76162716
83Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.73922726
84Oxytocin signaling pathway_Homo sapiens_hsa049210.73276057
85Phosphatidylinositol signaling system_Homo sapiens_hsa040700.71768243
86Type II diabetes mellitus_Homo sapiens_hsa049300.71595681
87Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.70814897
88Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.69540476
89Endocytosis_Homo sapiens_hsa041440.68861745
90Influenza A_Homo sapiens_hsa051640.68068340
91Longevity regulating pathway - mammal_Homo sapiens_hsa042110.67192790
92Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66451089
93Oxidative phosphorylation_Homo sapiens_hsa001900.65880129
94Glycosaminoglycan degradation_Homo sapiens_hsa005310.65488104
95Choline metabolism in cancer_Homo sapiens_hsa052310.64612456
96Galactose metabolism_Homo sapiens_hsa000520.64235081
97Pancreatic cancer_Homo sapiens_hsa052120.63747370
98Fructose and mannose metabolism_Homo sapiens_hsa000510.62790426
99Sphingolipid signaling pathway_Homo sapiens_hsa040710.62382885
100Phagosome_Homo sapiens_hsa041450.62193514
101Lysine degradation_Homo sapiens_hsa003100.61141111
102Prion diseases_Homo sapiens_hsa050200.60288625
103Epstein-Barr virus infection_Homo sapiens_hsa051690.60237823
104Intestinal immune network for IgA production_Homo sapiens_hsa046720.59987485
105Chemokine signaling pathway_Homo sapiens_hsa040620.59396787
106Glioma_Homo sapiens_hsa052140.59067869
107Vascular smooth muscle contraction_Homo sapiens_hsa042700.58870169
108Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.58548248
109Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.57618171
110Hepatitis B_Homo sapiens_hsa051610.57437607
111Neurotrophin signaling pathway_Homo sapiens_hsa047220.57365973
112Inositol phosphate metabolism_Homo sapiens_hsa005620.57110055
113Lysosome_Homo sapiens_hsa041420.56513849
114ErbB signaling pathway_Homo sapiens_hsa040120.55310629
115Renal cell carcinoma_Homo sapiens_hsa052110.55103177
116NOD-like receptor signaling pathway_Homo sapiens_hsa046210.54065038
117Pentose phosphate pathway_Homo sapiens_hsa000300.54055634
118Prostate cancer_Homo sapiens_hsa052150.53374696
119Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.53348010
120FoxO signaling pathway_Homo sapiens_hsa040680.53212723
121Estrogen signaling pathway_Homo sapiens_hsa049150.52808835
122MAPK signaling pathway_Homo sapiens_hsa040100.52308419
123Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.51719194
124mTOR signaling pathway_Homo sapiens_hsa041500.51643355
125Dorso-ventral axis formation_Homo sapiens_hsa043200.51453405
126Pyruvate metabolism_Homo sapiens_hsa006200.50774719
127Thyroid hormone signaling pathway_Homo sapiens_hsa049190.50335606
128Bladder cancer_Homo sapiens_hsa052190.50335427
129Viral carcinogenesis_Homo sapiens_hsa052030.47906003
130Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.46958338
131Antigen processing and presentation_Homo sapiens_hsa046120.46312169
132Non-small cell lung cancer_Homo sapiens_hsa052230.45669768
133HTLV-I infection_Homo sapiens_hsa051660.45213151
134Caffeine metabolism_Homo sapiens_hsa002320.44009938
135MicroRNAs in cancer_Homo sapiens_hsa052060.43582188
136Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.43184719

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