DYNLRB2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ventricular system development (GO:0021591)9.96883647
2UTP metabolic process (GO:0046051)9.79711092
3motile cilium assembly (GO:0044458)9.31659272
4left/right axis specification (GO:0070986)8.49451879
5CTP metabolic process (GO:0046036)8.09656376
6CTP biosynthetic process (GO:0006241)8.09656376
7guanosine-containing compound biosynthetic process (GO:1901070)8.04606703
8pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)7.43405859
9pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)7.05677575
10intraciliary transport (GO:0042073)6.87003441
11microtubule bundle formation (GO:0001578)6.39611960
12cilium organization (GO:0044782)6.22592849
13pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)6.16882157
14primary alcohol catabolic process (GO:0034310)5.94574268
15nucleotide phosphorylation (GO:0046939)5.93537798
16cilium assembly (GO:0042384)5.73966276
17pyrimidine nucleoside triphosphate metabolic process (GO:0009147)5.49633529
18vitamin transmembrane transport (GO:0035461)5.38836241
19nucleoside diphosphate metabolic process (GO:0009132)5.24920872
20ethanol metabolic process (GO:0006067)5.07125625
21centriole assembly (GO:0098534)5.02846777
22cellular component assembly involved in morphogenesis (GO:0010927)4.97002848
23regulation of cilium movement (GO:0003352)4.93863993
24cilium morphogenesis (GO:0060271)4.85146387
25diterpenoid biosynthetic process (GO:0016102)4.81471424
26pyrimidine ribonucleoside biosynthetic process (GO:0046132)4.69066880
27sperm capacitation (GO:0048240)4.57767995
28one-carbon compound transport (GO:0019755)4.52571132
29pyrimidine ribonucleotide biosynthetic process (GO:0009220)4.46653987
30* microtubule-based movement (GO:0007018)4.32677538
31regulation of glucose import in response to insulin stimulus (GO:2001273)4.22466085
32cell projection assembly (GO:0030031)4.19013239
33regulation of macrophage chemotaxis (GO:0010758)4.09903568
34pyrimidine-containing compound transmembrane transport (GO:0072531)4.07760307
35pyrimidine ribonucleotide metabolic process (GO:0009218)4.05403842
36lung epithelium development (GO:0060428)3.90150788
37ethanol oxidation (GO:0006069)3.87881247
38negative regulation of T cell differentiation in thymus (GO:0033085)3.86131001
39regulation of mononuclear cell migration (GO:0071675)3.82341438
40purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.82167321
41response to xenobiotic stimulus (GO:0009410)3.82064428
42centriole replication (GO:0007099)3.81061382
43brain morphogenesis (GO:0048854)3.79770931
44deoxyribonucleoside diphosphate metabolic process (GO:0009186)3.77326914
45purine nucleoside triphosphate biosynthetic process (GO:0009145)3.72949493
46tolerance induction (GO:0002507)3.64242101
47establishment of apical/basal cell polarity (GO:0035089)3.60892008
48glutathione derivative biosynthetic process (GO:1901687)3.58626882
49glutathione derivative metabolic process (GO:1901685)3.58626882
50retinoic acid metabolic process (GO:0042573)3.58595397
51negative regulation of inclusion body assembly (GO:0090084)3.55889534
52pyrimidine ribonucleoside metabolic process (GO:0046131)3.55844786
53regulation of interleukin-5 production (GO:0032674)3.53200627
54otic vesicle formation (GO:0030916)3.50382770
55ADP metabolic process (GO:0046031)3.46978123
56determination of left/right symmetry (GO:0007368)3.44205289
57pyrimidine nucleotide biosynthetic process (GO:0006221)3.43663051
58terpenoid biosynthetic process (GO:0016114)3.41672594
59establishment of monopolar cell polarity (GO:0061162)3.40915029
60establishment or maintenance of monopolar cell polarity (GO:0061339)3.40915029
61multicellular organismal aging (GO:0010259)3.40654664
62retinol metabolic process (GO:0042572)3.36197597
63negative regulation of B cell mediated immunity (GO:0002713)3.34735727
64negative regulation of immunoglobulin mediated immune response (GO:0002890)3.34735727
65ribonucleoside triphosphate biosynthetic process (GO:0009201)3.30954723
66determination of bilateral symmetry (GO:0009855)3.30451263
67nucleoside triphosphate biosynthetic process (GO:0009142)3.29392276
68specification of symmetry (GO:0009799)3.25311209
69cytoplasmic microtubule organization (GO:0031122)3.23412398
70microtubule depolymerization (GO:0007019)3.20715252
71sperm motility (GO:0030317)3.19571666
72positive regulation of cellular response to insulin stimulus (GO:1900078)3.18297932
73male meiosis I (GO:0007141)3.14324577
74primary alcohol metabolic process (GO:0034308)3.12920752
75regulation of microtubule-based movement (GO:0060632)3.12885843
76protein localization to cilium (GO:0061512)3.12379712
77exogenous drug catabolic process (GO:0042738)3.11547095
78pyrimidine nucleoside biosynthetic process (GO:0046134)3.07330260
79regulation of interleukin-13 production (GO:0032656)3.04517770
80negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.04174632
81regulation of germinal center formation (GO:0002634)3.03682097
82central nervous system myelination (GO:0022010)3.02591051
83axon ensheathment in central nervous system (GO:0032291)3.02591051
84oxygen transport (GO:0015671)3.02503770
85spermatid development (GO:0007286)3.01514207
86regulation of autophagic vacuole assembly (GO:2000785)2.99991027
87establishment of tissue polarity (GO:0007164)2.94512998
88establishment of planar polarity (GO:0001736)2.94512998
89protein polyglutamylation (GO:0018095)2.94380148
90protein refolding (GO:0042026)2.94276423
91microtubule severing (GO:0051013)2.90002688
92left/right pattern formation (GO:0060972)2.87917892
93aldehyde catabolic process (GO:0046185)2.87804392
94positive regulation of tolerance induction (GO:0002645)2.87692692
95single fertilization (GO:0007338)2.86674475
96O-glycan processing (GO:0016266)2.84212980
97retinal rod cell development (GO:0046548)2.83941897
98positive regulation of smoothened signaling pathway (GO:0045880)2.81894822
99eye photoreceptor cell differentiation (GO:0001754)2.80134525
100photoreceptor cell differentiation (GO:0046530)2.80134525
101microtubule polymerization or depolymerization (GO:0031109)2.74710981
102meiotic cell cycle (GO:0051321)2.74155517
103gas transport (GO:0015669)2.74136477
104carnitine metabolic process (GO:0009437)2.72028956
105embryonic camera-type eye development (GO:0031076)2.70083969
106lateral sprouting from an epithelium (GO:0060601)2.69482777
107lateral ventricle development (GO:0021670)2.68951056
108regulation of inclusion body assembly (GO:0090083)2.68906842
109regulation of vacuole organization (GO:0044088)2.67783986
110nonmotile primary cilium assembly (GO:0035058)2.67139222
111positive regulation of meiosis (GO:0045836)2.58512525
112regulation of pigment cell differentiation (GO:0050932)2.57669038
113regulation of mesenchymal cell apoptotic process (GO:2001053)2.57218109
114apical protein localization (GO:0045176)2.55157391
115pyrimidine-containing compound biosynthetic process (GO:0072528)2.53987835
116photoreceptor cell maintenance (GO:0045494)2.50240963
117intra-S DNA damage checkpoint (GO:0031573)2.49276307
118phenol-containing compound catabolic process (GO:0019336)2.47879191
119embryonic digestive tract development (GO:0048566)2.47726849
120hydrogen peroxide biosynthetic process (GO:0050665)2.47161707
121purine ribonucleoside diphosphate metabolic process (GO:0009179)2.47125062
122purine nucleoside diphosphate metabolic process (GO:0009135)2.47125062
123positive regulation of meiotic cell cycle (GO:0051446)2.46257870
124smoothened signaling pathway (GO:0007224)2.43137719
125glomerular epithelial cell development (GO:0072310)2.41470113
126organelle assembly (GO:0070925)2.41281390
127negative regulation of humoral immune response (GO:0002921)2.41146950
128fertilization (GO:0009566)2.40453467
129drug catabolic process (GO:0042737)2.40408692
130meiosis I (GO:0007127)2.39335209
131heart looping (GO:0001947)2.38852562
132excretion (GO:0007588)2.38552196
133multicellular organismal water homeostasis (GO:0050891)2.36854783
134phosphatidylcholine biosynthetic process (GO:0006656)2.36497362
135* microtubule-based process (GO:0007017)2.33225213
136pyrimidine nucleotide metabolic process (GO:0006220)2.32104078
137fusion of sperm to egg plasma membrane (GO:0007342)2.31524080
138heart valve formation (GO:0003188)2.31404073
139regulation of collateral sprouting (GO:0048670)2.31394767
140cellular response to nicotine (GO:0071316)2.31276759
141regulation of microtubule depolymerization (GO:0031114)2.30333607
142hydrogen peroxide catabolic process (GO:0042744)2.29243472
143purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.28830159
144epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.28556729
145positive regulation of extracellular matrix organization (GO:1903055)2.27350720
146glutathione metabolic process (GO:0006749)2.26654631
147regulation of smoothened signaling pathway (GO:0008589)2.24194221
148phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.23351242
149cilium movement (GO:0003341)17.5514992
150axonemal dynein complex assembly (GO:0070286)15.9636375
151axoneme assembly (GO:0035082)14.7406523
152cilium or flagellum-dependent cell motility (GO:0001539)13.4736703
153epithelial cilium movement (GO:0003351)13.0516083
154GTP biosynthetic process (GO:0006183)11.8008811
155epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)10.7915085
156nucleoside diphosphate phosphorylation (GO:0006165)10.6284843
157UTP biosynthetic process (GO:0006228)10.5607089

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.54423125
2RBPJ_22232070_ChIP-Seq_NCS_Mouse4.21946251
3CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human3.77081590
4CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.59415831
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.07251905
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.92676259
7FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.86615057
8TRIM28_21343339_ChIP-Seq_HEK293_Human2.32164244
9CTBP2_25329375_ChIP-Seq_LNCAP_Human2.21047978
10GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.03528921
11TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.94948999
12AR_21572438_ChIP-Seq_LNCaP_Human1.84161203
13EZH2_22144423_ChIP-Seq_EOC_Human1.78060679
14STAT1_20625510_ChIP-Seq_HELA_Human1.74724815
15CDX2_19796622_ChIP-Seq_MESCs_Mouse1.73715478
16* SMAD4_21799915_ChIP-Seq_A2780_Human1.70008195
17* RNF2_27304074_Chip-Seq_NSC_Mouse1.68312948
18SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.68253387
19FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.65487683
20* P300_19829295_ChIP-Seq_ESCs_Human1.62764131
21BCAT_22108803_ChIP-Seq_LS180_Human1.61023677
22ESR1_20079471_ChIP-ChIP_T-47D_Human1.60620189
23DROSHA_22980978_ChIP-Seq_HELA_Human1.57387044
24BMI1_23680149_ChIP-Seq_NPCS_Mouse1.54383333
25TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.53155428
26EZH2_27294783_Chip-Seq_ESCs_Mouse1.52023732
27* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.50482266
28CBX2_27304074_Chip-Seq_ESCs_Mouse1.50403304
29FOXA1_25552417_ChIP-Seq_VCAP_Human1.47489175
30* TP63_23658742_ChIP-Seq_EP156T_Human1.46570262
31CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.45554652
32PIAS1_25552417_ChIP-Seq_VCAP_Human1.45470116
33TOP2B_26459242_ChIP-Seq_MCF-7_Human1.44481805
34NR3C1_21868756_ChIP-Seq_MCF10A_Human1.44038977
35SUZ12_27294783_Chip-Seq_ESCs_Mouse1.43744603
36CTBP1_25329375_ChIP-Seq_LNCAP_Human1.43547424
37* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.42728230
38PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.41522867
39SUZ12_27294783_Chip-Seq_NPCs_Mouse1.41492268
40ETV1_20927104_ChIP-Seq_GIST48_Human1.38707607
41EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.38475679
42AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.38107468
43POU3F2_20337985_ChIP-ChIP_501MEL_Human1.36487212
44CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.36422503
45SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.35906971
46* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.34875480
47CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.34226436
48* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.34053158
49SMAD3_21741376_ChIP-Seq_EPCs_Human1.33738401
50HNFA_21074721_ChIP-Seq_CACO-2_Human1.32566256
51PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.31965746
52CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.31588711
53TCF4_22108803_ChIP-Seq_LS180_Human1.31449535
54FLI1_27457419_Chip-Seq_LIVER_Mouse1.31356746
55* RUNX1_27514584_Chip-Seq_MCF-7_Human1.30659544
56CTNNB1_20460455_ChIP-Seq_HCT116_Human1.30480027
57SMRT_27268052_Chip-Seq_Bcells_Human1.28850863
58TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.28409967
59PCGF2_27294783_Chip-Seq_ESCs_Mouse1.27538066
60LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.27498612
61E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.27496692
62EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.27028173
63SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.25070127
64SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.24173591
65PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.22813595
66JARID2_20075857_ChIP-Seq_MESCs_Mouse1.21954592
67EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.21765347
68SMAD4_21741376_ChIP-Seq_EPCs_Human1.21113313
69TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.20277644
70ARNT_22903824_ChIP-Seq_MCF-7_Human1.20248453
71PCGF2_27294783_Chip-Seq_NPCs_Mouse1.20156894
72* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.19990782
73ZFP57_27257070_Chip-Seq_ESCs_Mouse1.19311310
74TDRD3_21172665_ChIP-Seq_MCF-7_Human1.19107541
75RBPJ_21746931_ChIP-Seq_IB4_Human1.18886389
76SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.18708805
77SOX2_27498859_Chip-Seq_STOMACH_Mouse1.18558468
78NFYA_21822215_ChIP-Seq_K562_Human1.17651708
79PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.17506142
80SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.17040414
81CBP_20019798_ChIP-Seq_JUKART_Human1.16925142
82IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.16925142
83RAD21_21589869_ChIP-Seq_MESCs_Mouse1.16411302
84ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.15497322
85SMC4_20622854_ChIP-Seq_HELA_Human1.14397221
86EZH2_27304074_Chip-Seq_ESCs_Mouse1.14385709
87* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.13323485
88* ER_23166858_ChIP-Seq_MCF-7_Human1.13183427
89AUTS2_25519132_ChIP-Seq_293T-REX_Human1.12796113
90FLI1_21867929_ChIP-Seq_TH2_Mouse1.12633520
91NFE2_27457419_Chip-Seq_LIVER_Mouse1.12585158
92CJUN_26792858_Chip-Seq_BT549_Human1.12122677
93PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.12083623
94STAT3_23295773_ChIP-Seq_U87_Human1.12037689
95NANOG_18555785_Chip-Seq_ESCs_Mouse1.12007326
96* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.11459074
97GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.11360839
98MTF2_20144788_ChIP-Seq_MESCs_Mouse1.10971081
99GBX2_23144817_ChIP-Seq_PC3_Human1.10572154
100LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.10344149
101TBL1_22424771_ChIP-Seq_293T_Human1.10198337
102* GATA1_26923725_Chip-Seq_HPCs_Mouse1.09672726
103AR_20517297_ChIP-Seq_VCAP_Human1.09347181
104JARID2_20064375_ChIP-Seq_MESCs_Mouse1.09287327
105GATA6_21074721_ChIP-Seq_CACO-2_Human1.08885304
106SOX2_20726797_ChIP-Seq_SW620_Human1.08860398
107GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.08559037
108CBX2_22325352_ChIP-Seq_293T-Rex_Human1.08511379
109SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.08344022
110MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.07883624
111TAF15_26573619_Chip-Seq_HEK293_Human1.07883167
112* TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07599393
113* POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.07599393
114KLF5_25053715_ChIP-Seq_YYC3_Human1.07439076
115ZNF217_24962896_ChIP-Seq_MCF-7_Human1.07348831
116GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.07087866
117SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.06421625
118ESR1_21235772_ChIP-Seq_MCF-7_Human1.06370242
119* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.06015721
120* SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.05780750
121TAL1_26923725_Chip-Seq_HPCs_Mouse1.05709507
122ZFX_18555785_Chip-Seq_ESCs_Mouse1.05591668
123TP53_18474530_ChIP-ChIP_U2OS_Human1.05405213
124ERG_20517297_ChIP-Seq_VCAP_Human1.05256137
125TP53_16413492_ChIP-PET_HCT116_Human1.05085685
126* TP63_22573176_ChIP-Seq_HFKS_Human1.04883338
127FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.04312191
128EZH2_18974828_ChIP-Seq_MESCs_Mouse1.02223256
129RNF2_18974828_ChIP-Seq_MESCs_Mouse1.02223256
130STAT3_18555785_Chip-Seq_ESCs_Mouse1.02013766
131CDX2_20551321_ChIP-Seq_CACO-2_Human1.01938359
132FOXA1_25329375_ChIP-Seq_VCAP_Human1.01834400
133FOXA1_27270436_Chip-Seq_PROSTATE_Human1.01834400
134VDR_22108803_ChIP-Seq_LS180_Human1.01651275
135SOX2_18555785_Chip-Seq_ESCs_Mouse1.01219989
136AHR_22903824_ChIP-Seq_MCF-7_Human1.00730660
137SUZ12_18555785_Chip-Seq_ESCs_Mouse1.00257358
138NFYB_21822215_ChIP-Seq_K562_Human0.99988232
139FUS_26573619_Chip-Seq_HEK293_Human0.99818345
140TCF4_23295773_ChIP-Seq_U87_Human0.99432065
141EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.99267532
142PHF8_20622853_ChIP-Seq_HELA_Human0.99002456
143MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98955513
144CRX_20693478_ChIP-Seq_RETINA_Mouse0.97720197
145TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.96746675
146WDR5_24793694_ChIP-Seq_LNCAP_Human0.95064024
147ELF1_20517297_ChIP-Seq_JURKAT_Human0.94763590
148CBP_21632823_ChIP-Seq_H3396_Human0.94350187
149AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.94330004
150CEBPB_22108803_ChIP-Seq_LS180_Human0.92869845
151GATA4_25053715_ChIP-Seq_YYC3_Human0.92455464
152ESR2_21235772_ChIP-Seq_MCF-7_Human0.92093845
153SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.91752548
154CTCF_20526341_ChIP-Seq_ESCs_Human0.90713994
155SMAD3_21741376_ChIP-Seq_HESCs_Human0.89756996
156CDX2_22108803_ChIP-Seq_LS180_Human0.89591015
157* RUNX2_22187159_ChIP-Seq_PCA_Human0.88769402

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color7.25442822
2MP0002653_abnormal_ependyma_morphology5.01484465
3MP0008004_abnormal_stomach_pH4.64762238
4MP0005623_abnormal_meninges_morphology4.27330594
5MP0000566_synostosis4.22155325
6MP0004043_abnormal_pH_regulation3.53994573
7MP0004133_heterotaxia3.25106161
8MP0001984_abnormal_olfaction3.20485692
9MP0005646_abnormal_pituitary_gland3.12895130
10MP0009780_abnormal_chondrocyte_physiolo3.11466915
11MP0005410_abnormal_fertilization2.78480316
12MP0004019_abnormal_vitamin_homeostasis2.53583383
13MP0001440_abnormal_grooming_behavior2.30555462
14MP0003878_abnormal_ear_physiology2.23686081
15MP0005377_hearing/vestibular/ear_phenot2.23686081
16MP0000383_abnormal_hair_follicle2.22915271
17MP0002282_abnormal_trachea_morphology2.21781604
18MP0002928_abnormal_bile_duct2.06772742
19MP0002160_abnormal_reproductive_system2.05716149
20MP0004782_abnormal_surfactant_physiolog2.03637354
21MP0002249_abnormal_larynx_morphology2.00908092
22MP0010678_abnormal_skin_adnexa1.88430558
23MP0009046_muscle_twitch1.85743780
24MP0003698_abnormal_male_reproductive1.76488037
25MP0002822_catalepsy1.76450424
26MP0004858_abnormal_nervous_system1.69679309
27MP0003806_abnormal_nucleotide_metabolis1.67408421
28MP0001177_atelectasis1.65145257
29MP0003937_abnormal_limbs/digits/tail_de1.61118402
30MP0005388_respiratory_system_phenotype1.58212537
31MP0002133_abnormal_respiratory_system1.58212537
32MP0003690_abnormal_glial_cell1.50581614
33MP0010030_abnormal_orbit_morphology1.50443039
34MP0001929_abnormal_gametogenesis1.50156249
35MP0004381_abnormal_hair_follicle1.43479604
36MP0000778_abnormal_nervous_system1.41856490
37MP0000049_abnormal_middle_ear1.41586703
38MP0001485_abnormal_pinna_reflex1.39413178
39MP0005083_abnormal_biliary_tract1.38886908
40MP0003656_abnormal_erythrocyte_physiolo1.37113444
41MP0002132_abnormal_respiratory_system1.36013864
42MP0003634_abnormal_glial_cell1.35626553
43MP0002938_white_spotting1.34626383
44MP0003938_abnormal_ear_development1.34357035
45MP0005389_reproductive_system_phenotype1.32959423
46MP0005551_abnormal_eye_electrophysiolog1.29456458
47MP0008789_abnormal_olfactory_epithelium1.25902086
48MP0009250_abnormal_appendicular_skeleto1.25697199
49MP0000428_abnormal_craniofacial_morphol1.25518350
50MP0002734_abnormal_mechanical_nocicepti1.18712951
51MP0002557_abnormal_social/conspecific_i1.17287233
52MP0001851_eye_inflammation1.15674127
53MP0001958_emphysema1.12877978
54MP0000631_abnormal_neuroendocrine_gland1.12331352
55MP0005408_hypopigmentation1.10101766
56MP0001270_distended_abdomen1.10036636
57MP0003950_abnormal_plasma_membrane1.09206412
58MP0001346_abnormal_lacrimal_gland1.08141292
59MP0002234_abnormal_pharynx_morphology1.07137927
60MP0005365_abnormal_bile_salt1.06356476
61MP0002736_abnormal_nociception_after1.01495400
62MP0005248_abnormal_Harderian_gland1.01008062
63MP0005394_taste/olfaction_phenotype0.99582457
64MP0005499_abnormal_olfactory_system0.99582457
65MP0008875_abnormal_xenobiotic_pharmacok0.99534537
66MP0005423_abnormal_somatic_nervous0.99310722
67MP0002210_abnormal_sex_determination0.98625082
68MP0002735_abnormal_chemical_nociception0.98486974
69MP0000613_abnormal_salivary_gland0.97852468
70MP0005636_abnormal_mineral_homeostasis0.96859099
71MP0001879_abnormal_lymphatic_vessel0.96858106
72MP0005220_abnormal_exocrine_pancreas0.96516370
73MP0001501_abnormal_sleep_pattern0.96373743
74MP0003283_abnormal_digestive_organ0.95330832
75MP0002233_abnormal_nose_morphology0.95195633
76MP0001968_abnormal_touch/_nociception0.94370068
77MP0002277_abnormal_respiratory_mucosa0.93008590
78MP0000470_abnormal_stomach_morphology0.91208110
79MP0003879_abnormal_hair_cell0.90540968
80MP0002139_abnormal_hepatobiliary_system0.90439473
81MP0003186_abnormal_redox_activity0.90206905
82MP0002168_other_aberrant_phenotype0.89393923
83MP0005379_endocrine/exocrine_gland_phen0.88314699
84MP0001293_anophthalmia0.87944142
85MP0003880_abnormal_central_pattern0.85926397
86MP0001324_abnormal_eye_pigmentation0.85174438
87MP0003942_abnormal_urinary_system0.84655082
88MP0002405_respiratory_system_inflammati0.83586531
89MP0004142_abnormal_muscle_tone0.83312761
90MP0002161_abnormal_fertility/fecundity0.82911058
91MP0002064_seizures0.82496414
92MP0001765_abnormal_ion_homeostasis0.82029226
93MP0005391_vision/eye_phenotype0.80648315
94MP0002572_abnormal_emotion/affect_behav0.80617356
95MP0005167_abnormal_blood-brain_barrier0.79415491
96MP0001986_abnormal_taste_sensitivity0.79220637
97MP0003861_abnormal_nervous_system0.78896839
98MP0009745_abnormal_behavioral_response0.78721500
99MP0005085_abnormal_gallbladder_physiolo0.78524274
100MP0001286_abnormal_eye_development0.78344169
101MP0002332_abnormal_exercise_endurance0.78265768
102MP0005253_abnormal_eye_physiology0.77925410
103MP0002152_abnormal_brain_morphology0.77855704
104MP0002638_abnormal_pupillary_reflex0.76724106
105MP0000026_abnormal_inner_ear0.76356444
106MP0005503_abnormal_tendon_morphology0.75863727
107MP0005647_abnormal_sex_gland0.75616185
108MP0002116_abnormal_craniofacial_bone0.75144189
109MP0010234_abnormal_vibrissa_follicle0.74449354
110MP0006292_abnormal_olfactory_placode0.74307666
111MP0009379_abnormal_foot_pigmentation0.73966514
112MP0002752_abnormal_somatic_nervous0.73872040
113MP0001529_abnormal_vocalization0.73808192
114MP0009384_cardiac_valve_regurgitation0.73085732
115MP0002909_abnormal_adrenal_gland0.72148346
116MP0008995_early_reproductive_senescence0.72071644
117MP0005187_abnormal_penis_morphology0.71911745
118MP0004883_abnormal_blood_vessel0.71552545
119MP0008961_abnormal_basal_metabolism0.71217447
120MP0006276_abnormal_autonomic_nervous0.70714911
121MP0005195_abnormal_posterior_eye0.70549527
122MP0002092_abnormal_eye_morphology0.69694890
123MP0002272_abnormal_nervous_system0.69040682
124MP0002896_abnormal_bone_mineralization0.68709912
125MP0001905_abnormal_dopamine_level0.66568061
126MP0006072_abnormal_retinal_apoptosis0.66512214
127MP0004270_analgesia0.65963816
128MP0001944_abnormal_pancreas_morphology0.65699317
129MP0004272_abnormal_basement_membrane0.65465379
130MP0001486_abnormal_startle_reflex0.64489178
131MP0001340_abnormal_eyelid_morphology0.63342273
132MP0004145_abnormal_muscle_electrophysio0.62870517
133MP0004742_abnormal_vestibular_system0.62278647
134MP0002876_abnormal_thyroid_physiology0.61798480
135MP0001970_abnormal_pain_threshold0.61613422
136MP0009643_abnormal_urine_homeostasis0.61518649
137MP0000678_abnormal_parathyroid_gland0.61067929
138MP0005395_other_phenotype0.60434392
139MP0009703_decreased_birth_body0.59107428
140MP0000013_abnormal_adipose_tissue0.58167570
141MP0002098_abnormal_vibrissa_morphology0.57997547
142MP0001963_abnormal_hearing_physiology0.57739804
143MP0003890_abnormal_embryonic-extraembry0.57526616
144MP0005165_increased_susceptibility_to0.55495198
145MP0005164_abnormal_response_to0.55182459
146MP0001502_abnormal_circadian_rhythm0.55093646
147MP0009765_abnormal_xenobiotic_induced0.52848872
148MP0006036_abnormal_mitochondrial_physio0.52200108
149MP0000681_abnormal_thyroid_gland0.51655616
150MP0000955_abnormal_spinal_cord0.50881854
151MP0008872_abnormal_physiological_respon0.50218012

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium morphology (HP:0005938)9.79595511
2Abnormal respiratory epithelium morphology (HP:0012253)9.79595511
3Absent/shortened dynein arms (HP:0200106)7.99933714
4Dynein arm defect of respiratory motile cilia (HP:0012255)7.99933714
5Chronic bronchitis (HP:0004469)7.54708597
6Bronchiectasis (HP:0002110)6.28113844
7Pancreatic fibrosis (HP:0100732)4.78208724
8True hermaphroditism (HP:0010459)4.41381298
9Nasal polyposis (HP:0100582)4.30450302
10Chronic sinusitis (HP:0011109)4.27739438
11Recurrent sinusitis (HP:0011108)3.88079197
12Bronchitis (HP:0012387)3.70918541
13Abnormality of the nasal mucosa (HP:0000433)3.59110210
14Nephronophthisis (HP:0000090)3.42197488
15Occipital encephalocele (HP:0002085)3.25394689
16Pancreatic cysts (HP:0001737)3.23541972
17Median cleft lip (HP:0000161)3.15271191
18Molar tooth sign on MRI (HP:0002419)3.10360717
19Abnormality of midbrain morphology (HP:0002418)3.10360717
20Tubulointerstitial nephritis (HP:0001970)3.04497047
21Supernumerary spleens (HP:0009799)3.03498494
22Abnormality of dentin (HP:0010299)3.02737715
23Infertility (HP:0000789)2.97957060
24Chronic otitis media (HP:0000389)2.91405639
25Cystic liver disease (HP:0006706)2.91026660
26Medial flaring of the eyebrow (HP:0010747)2.87880643
27Congenital hepatic fibrosis (HP:0002612)2.76231591
28Chronic hepatic failure (HP:0100626)2.72715994
29Gait imbalance (HP:0002141)2.68760617
30Abnormal biliary tract physiology (HP:0012439)2.66303137
31Bile duct proliferation (HP:0001408)2.66303137
32Congenital primary aphakia (HP:0007707)2.66164752
33Abnormality of the renal medulla (HP:0100957)2.64947360
34Recurrent otitis media (HP:0000403)2.63931028
35Postaxial foot polydactyly (HP:0001830)2.63896103
36Aplasia/Hypoplasia of the tongue (HP:0010295)2.55796510
37Neoplasm of head and neck (HP:0012288)2.51704751
38Esophageal neoplasm (HP:0100751)2.51704751
39Tubular atrophy (HP:0000092)2.47254661
40Hyperactive renin-angiotensin system (HP:0000841)2.47037194
41Nephrogenic diabetes insipidus (HP:0009806)2.36806637
42Genital tract atresia (HP:0001827)2.20932341
43Anencephaly (HP:0002323)2.16861183
44Abnormality of the dental root (HP:0006486)2.13174775
45Taurodontia (HP:0000679)2.13174775
46Abnormality of permanent molar morphology (HP:0011071)2.13174775
47Preaxial hand polydactyly (HP:0001177)2.03229590
48Abnormal respiratory motile cilium physiology (HP:0012261)13.1380389
49Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.9815781
50Abnormal ciliary motility (HP:0012262)12.7230236
51Rhinitis (HP:0012384)11.0318517
52Vaginal atresia (HP:0000148)1.99616610
53Facial cleft (HP:0002006)1.99337321
54Stage 5 chronic kidney disease (HP:0003774)1.98449063
55Abnormality of molar (HP:0011077)1.97157949
56Abnormality of molar morphology (HP:0011070)1.97157949
57Sclerocornea (HP:0000647)1.97037479
58Abnormality of the dental pulp (HP:0006479)1.95810377
59Postaxial hand polydactyly (HP:0001162)1.94851447
60Male pseudohermaphroditism (HP:0000037)1.92421269
61Tubulointerstitial abnormality (HP:0001969)1.91100313
62Atelectasis (HP:0100750)1.90613388
63Fibular hypoplasia (HP:0003038)1.89367089
64Poor coordination (HP:0002370)1.87228241
65Abnormality of abdominal situs (HP:0011620)1.82862340
66Abdominal situs inversus (HP:0003363)1.82862340
67Furrowed tongue (HP:0000221)1.80040662
68Abnormal sex determination (HP:0012244)1.74453756
69Sex reversal (HP:0012245)1.74453756
70Aplasia/Hypoplasia of the spleen (HP:0010451)1.67637935
71Asplenia (HP:0001746)1.66841688
72Concave nail (HP:0001598)1.66380697
73Decreased circulating renin level (HP:0003351)1.64556726
74Oculomotor apraxia (HP:0000657)1.64485490
75Absent frontal sinuses (HP:0002688)1.62788051
76Aplasia/Hypoplasia of the lens (HP:0008063)1.60522631
77Bifid tongue (HP:0010297)1.50439852
78Abnormal drinking behavior (HP:0030082)1.48823745
79Polydipsia (HP:0001959)1.48823745
80Abnormality of the renal cortex (HP:0011035)1.44690534
81Renal salt wasting (HP:0000127)1.41823358
82Absent rod-and cone-mediated responses on ERG (HP:0007688)1.32805733
83Broad distal phalanx of finger (HP:0009836)1.31720392
84Nephropathy (HP:0000112)1.31651564
85Neonatal short-limb short stature (HP:0008921)1.31465309
86Short nail (HP:0001799)1.31309464
87Hypodontia (HP:0000668)1.31160690
88Ectopic anus (HP:0004397)1.29765182
89Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.29408268
90Bronchomalacia (HP:0002780)1.28406340
91Hypotelorism (HP:0000601)1.26968117
92Hyperkalemia (HP:0002153)1.26320994
93Polycystic kidney dysplasia (HP:0000113)1.25312189
94Bell-shaped thorax (HP:0001591)1.24698746
95Tubulointerstitial fibrosis (HP:0005576)1.23314414
96Central scotoma (HP:0000603)1.22948252
97Abnormality of renin-angiotensin system (HP:0000847)1.22196920
98Male infertility (HP:0003251)1.22033835
99Narrow forehead (HP:0000341)1.19337261
100Abnormality of macular pigmentation (HP:0008002)1.18596041
101Hyperaldosteronism (HP:0000859)1.17265183
102Broad foot (HP:0001769)1.17165777
103Specific learning disability (HP:0001328)1.16914413
104Polycystic ovaries (HP:0000147)1.16436478
105Decreased central vision (HP:0007663)1.15881602
106Retinitis pigmentosa (HP:0000510)1.15193605
107Recurrent bronchitis (HP:0002837)1.15058505
108Back pain (HP:0003418)1.14662797
109Aplasia/Hypoplasia of the fibula (HP:0006492)1.12704322
110Optic nerve coloboma (HP:0000588)1.11995036
111Short thorax (HP:0010306)1.11982242
112Abnormality of chloride homeostasis (HP:0011422)1.11575831
113Abnormality of the frontal sinuses (HP:0002687)1.10869535
114Abnormal rod and cone electroretinograms (HP:0008323)1.09551744
115Bifid scrotum (HP:0000048)1.09108958
11611 pairs of ribs (HP:0000878)1.08259207
117Retinal dysplasia (HP:0007973)1.05955701
118Aganglionic megacolon (HP:0002251)1.05892709
119Omphalocele (HP:0001539)1.05747881
120Prominent nasal bridge (HP:0000426)1.05690076
121Multicystic kidney dysplasia (HP:0000003)1.02930333
122Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.02720787
123Glucose intolerance (HP:0000833)0.97204473
124Highly arched eyebrow (HP:0002553)0.95915316
125Hypokalemic alkalosis (HP:0001949)0.94940190

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PNCK7.63216050
2EPHA23.48226434
3MST43.15746003
4MAPKAPK32.58354871
5GRK12.19220387
6WEE12.04727107
7VRK12.02627362
8MAPK1510.3966186
9STK241.96981905
10SIK11.86408685
11NME11.64461536
12MKNK21.58720422
13TLK11.58543005
14STK161.56889343
15FRK1.48634566
16EPHA31.45807002
17INSRR1.44694114
18NTRK21.44548282
19LMTK21.41552891
20DAPK21.35433107
21STK38L1.29537222
22PHKG21.24536717
23PHKG11.24536717
24STK101.23584548
25PDK41.23304275
26PDK31.23304275
27EPHB11.19891888
28PAK21.14816606
29MAP3K31.13708914
30PTK2B1.10339396
31FGFR21.07169432
32DYRK31.04674062
33TTK1.03775652
34CDK31.01673576
35PAK30.95364405
36MAP4K20.95204381
37STK380.94806391
38PRKCG0.94200122
39ERBB30.93288321
40CCNB10.92296533
41GRK50.91125370
42PASK0.89664965
43IRAK10.84425920
44CAMKK10.80826221
45ROCK20.80321665
46STK390.79854422
47CAMKK20.78825890
48LATS10.78579906
49GSK3A0.77932685
50MAP3K70.77627707
51GRK70.76680416
52PINK10.76156402
53DMPK0.75063105
54RPS6KA20.74950716
55WNK30.74817385
56AURKA0.74785821
57MKNK10.73483874
58PLK20.71607299
59TAOK10.71364860
60NEK90.71288055
61CASK0.71019843
62PIK3CG0.69500860
63ROCK10.68408297
64MAP3K20.67728422
65PRKCI0.67627961
66BCR0.67183280
67MAP2K40.67038860
68EEF2K0.66093599
69TRIM280.63843233
70TGFBR20.63692486
71ERBB20.63635917
72PDK20.63519688
73MAP2K70.63302246
74MYLK0.62409011
75SMG10.61324191
76ITK0.60909559
77MAP2K20.60769897
78BMPR1B0.60533611
79PRKCE0.59549961
80MAPKAPK50.58183506
81MOS0.56421831
82SGK4940.56331728
83SGK2230.56331728
84PRKD30.56087224
85DYRK20.54370399
86MAPKAPK20.52325348
87TEC0.51755146
88CDK80.51070089
89TESK10.47687301
90MST1R0.47300638
91BRSK20.47094413
92WNK40.46709262
93MARK20.46572740
94TRPM70.46571056
95CAMK2B0.46268409
96RPS6KA40.45585407
97PRKG10.45382943
98MAP3K120.44864151
99LRRK20.44236517
100MUSK0.43949818
101DYRK1A0.43805772
102IRAK20.43395855
103RPS6KA50.43154287
104PRKACA0.42562569
105CAMK2A0.42165907
106EPHA40.40721615
107PTK20.40467118
108HIPK20.39706488
109FER0.39454074
110CDK190.39318604
111MARK10.39305258
112RPS6KB20.38243940
113CSK0.38138725
114NLK0.38044938
115CAMK1G0.37698097
116PRKCQ0.37571091
117TIE10.36103347
118MAP3K60.35794882
119PRKAA20.35585596
120SGK10.35485926
121PRKCD0.35032272
122MAPK130.34231136
123NTRK30.33400466
124BMPR20.33213197
125CAMK2D0.33122356
126PRKACG0.33044115
127ADRBK10.32337593
128OXSR10.32331454
129ADRBK20.32209197
130MINK10.32043794
131TSSK60.32034249
132SRC0.30532038
133DYRK1B0.30482049
134RPS6KL10.30309015
135RPS6KC10.30309015
136WNK10.29919912
137AKT20.29641150
138YES10.29641041
139SGK20.29553371
140TBK10.29319693
141MAP3K40.28692368
142PRKCH0.27944824
143NEK60.27894721
144CSNK1G10.27604714
145PKN10.27576853
146PLK40.27088285
147GRK60.26393935
148CSNK1G20.26329029
149CAMK2G0.26229422
150ACVR1B0.24821010
151MAPK70.24583278
152PRKG20.23453675
153PRKDC0.23393686
154PLK30.23241063
155PRKCA0.22788408
156FGFR30.22260708
157STK110.20326696
158CHUK0.19308970

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000725.05515030
2Phenylalanine metabolism_Homo sapiens_hsa003603.96783826
3Huntingtons disease_Homo sapiens_hsa050163.77377380
4Olfactory transduction_Homo sapiens_hsa047402.92211075
5Vitamin B6 metabolism_Homo sapiens_hsa007502.81399942
6beta-Alanine metabolism_Homo sapiens_hsa004102.70080943
7Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.32803491
8Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.27151089
9Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.26997026
10Caffeine metabolism_Homo sapiens_hsa002322.07854079
11Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.77684576
12Butanoate metabolism_Homo sapiens_hsa006501.72733836
13Oxidative phosphorylation_Homo sapiens_hsa001901.65145568
14Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.63550224
15Phototransduction_Homo sapiens_hsa047441.62008905
16PPAR signaling pathway_Homo sapiens_hsa033201.60105089
17Glutathione metabolism_Homo sapiens_hsa004801.59462901
18Amphetamine addiction_Homo sapiens_hsa050311.57962274
19Gastric acid secretion_Homo sapiens_hsa049711.57171378
20Sulfur metabolism_Homo sapiens_hsa009201.56584289
21Steroid hormone biosynthesis_Homo sapiens_hsa001401.56254172
22Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.56122281
23Histidine metabolism_Homo sapiens_hsa003401.54050582
24Pyruvate metabolism_Homo sapiens_hsa006201.50002277
25Chemical carcinogenesis_Homo sapiens_hsa052041.39135963
26Ether lipid metabolism_Homo sapiens_hsa005651.38851354
27Taste transduction_Homo sapiens_hsa047421.37087129
28Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.35918956
29GABAergic synapse_Homo sapiens_hsa047271.33611030
30ABC transporters_Homo sapiens_hsa020101.31555295
31Insulin secretion_Homo sapiens_hsa049111.31198797
32Arachidonic acid metabolism_Homo sapiens_hsa005901.30760445
33Alzheimers disease_Homo sapiens_hsa050101.28806513
34Hedgehog signaling pathway_Homo sapiens_hsa043401.25220197
35Parkinsons disease_Homo sapiens_hsa050121.20574150
36Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.19052939
37Basal cell carcinoma_Homo sapiens_hsa052171.15039620
38Circadian entrainment_Homo sapiens_hsa047131.14027013
39Estrogen signaling pathway_Homo sapiens_hsa049151.12463495
40Protein export_Homo sapiens_hsa030601.11930068
41Glutamatergic synapse_Homo sapiens_hsa047241.11094203
42Circadian rhythm_Homo sapiens_hsa047101.10808577
43Cocaine addiction_Homo sapiens_hsa050301.09638777
44Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.07097446
45Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.06637106
46Retinol metabolism_Homo sapiens_hsa008301.06232236
47Purine metabolism_Homo sapiens_hsa002301.04595818
48Nicotine addiction_Homo sapiens_hsa050331.03276756
49Calcium signaling pathway_Homo sapiens_hsa040201.03106248
50Peroxisome_Homo sapiens_hsa041461.02524660
51Fatty acid degradation_Homo sapiens_hsa000711.01385794
52Cardiac muscle contraction_Homo sapiens_hsa042601.01105973
53Propanoate metabolism_Homo sapiens_hsa006401.00879397
54Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.00519687
55Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.98716757
56Mineral absorption_Homo sapiens_hsa049780.96788775
57Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.93473721
58Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.93371452
59Renin secretion_Homo sapiens_hsa049240.93188337
60Thyroid hormone synthesis_Homo sapiens_hsa049180.92432812
61Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.92129844
62Ovarian steroidogenesis_Homo sapiens_hsa049130.88403389
63Dorso-ventral axis formation_Homo sapiens_hsa043200.87391810
64Sphingolipid metabolism_Homo sapiens_hsa006000.86047058
65cAMP signaling pathway_Homo sapiens_hsa040240.85502132
66Wnt signaling pathway_Homo sapiens_hsa043100.84641806
67Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.82448077
68Salivary secretion_Homo sapiens_hsa049700.80960150
69Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.79754890
70Fatty acid elongation_Homo sapiens_hsa000620.79288604
71Carbohydrate digestion and absorption_Homo sapiens_hsa049730.75212606
72Linoleic acid metabolism_Homo sapiens_hsa005910.75198560
73Morphine addiction_Homo sapiens_hsa050320.74853803
74Melanogenesis_Homo sapiens_hsa049160.73476322
75Hippo signaling pathway_Homo sapiens_hsa043900.73265754
76Dopaminergic synapse_Homo sapiens_hsa047280.73084692
77Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.70201986
78alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.66825621
79Vascular smooth muscle contraction_Homo sapiens_hsa042700.66778802
80Prion diseases_Homo sapiens_hsa050200.66646171
81Bile secretion_Homo sapiens_hsa049760.66553178
82Starch and sucrose metabolism_Homo sapiens_hsa005000.64397060
83Nitrogen metabolism_Homo sapiens_hsa009100.64319398
84Glucagon signaling pathway_Homo sapiens_hsa049220.63881848
85cGMP-PKG signaling pathway_Homo sapiens_hsa040220.61710047
86Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.59846450
87Fatty acid biosynthesis_Homo sapiens_hsa000610.59623603
88Glycerophospholipid metabolism_Homo sapiens_hsa005640.59250880
89Serotonergic synapse_Homo sapiens_hsa047260.59096846
90Pentose and glucuronate interconversions_Homo sapiens_hsa000400.59053376
91Aldosterone synthesis and secretion_Homo sapiens_hsa049250.58412261
92Drug metabolism - other enzymes_Homo sapiens_hsa009830.57597931
93Primary bile acid biosynthesis_Homo sapiens_hsa001200.57550196
94Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.56871355
95Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.56741932
96SNARE interactions in vesicular transport_Homo sapiens_hsa041300.56076536
97Alcoholism_Homo sapiens_hsa050340.55793833
98Maturity onset diabetes of the young_Homo sapiens_hsa049500.54127817
99Notch signaling pathway_Homo sapiens_hsa043300.53687021
100Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.52268735
101Collecting duct acid secretion_Homo sapiens_hsa049660.51737131
102Glycerolipid metabolism_Homo sapiens_hsa005610.50050517
103Tight junction_Homo sapiens_hsa045300.49896267
104Nucleotide excision repair_Homo sapiens_hsa034200.45102134
105Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.44987608
106Phagosome_Homo sapiens_hsa041450.44669728
107Tryptophan metabolism_Homo sapiens_hsa003800.44490000
108Gap junction_Homo sapiens_hsa045400.43932068
109Regulation of autophagy_Homo sapiens_hsa041400.43126750
110Pyrimidine metabolism_Homo sapiens_hsa002400.43056406
111Vitamin digestion and absorption_Homo sapiens_hsa049770.40921092
112Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.40865758
113Metabolic pathways_Homo sapiens_hsa011000.40440102
114Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.40368568
115GnRH signaling pathway_Homo sapiens_hsa049120.39525940
116Pancreatic secretion_Homo sapiens_hsa049720.39472507
117Steroid biosynthesis_Homo sapiens_hsa001000.39328939
118Cholinergic synapse_Homo sapiens_hsa047250.39168203
119Tyrosine metabolism_Homo sapiens_hsa003500.38271123
120Vibrio cholerae infection_Homo sapiens_hsa051100.37564079
121Antigen processing and presentation_Homo sapiens_hsa046120.37484525
122Systemic lupus erythematosus_Homo sapiens_hsa053220.37449181
123Synaptic vesicle cycle_Homo sapiens_hsa047210.37136354
124Arginine and proline metabolism_Homo sapiens_hsa003300.35927132
125Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.33982235
126Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.33599128
127Complement and coagulation cascades_Homo sapiens_hsa046100.24437640
128N-Glycan biosynthesis_Homo sapiens_hsa005100.23422844
129Choline metabolism in cancer_Homo sapiens_hsa052310.22482468
130Glycosaminoglycan degradation_Homo sapiens_hsa005310.20974093
131Arginine biosynthesis_Homo sapiens_hsa002200.19819857
132Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.15543739

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