DYNLL2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)5.81044194
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.46174395
3locomotory exploration behavior (GO:0035641)5.43290950
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.23942718
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.59950603
6glutamate secretion (GO:0014047)4.47078016
7vocalization behavior (GO:0071625)4.45896217
8cerebellar granule cell differentiation (GO:0021707)4.42172937
9regulation of synaptic vesicle exocytosis (GO:2000300)4.42105561
10layer formation in cerebral cortex (GO:0021819)4.37503472
11synaptic vesicle exocytosis (GO:0016079)4.35185880
12synaptic vesicle docking involved in exocytosis (GO:0016081)4.30324080
13sodium ion export (GO:0071436)4.18159596
14neurotransmitter secretion (GO:0007269)4.17857055
15regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.14703121
16cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.05217681
17regulation of synapse structural plasticity (GO:0051823)4.00825367
18regulation of glutamate receptor signaling pathway (GO:1900449)3.99888009
19activation of protein kinase A activity (GO:0034199)3.98281980
20regulation of synaptic vesicle transport (GO:1902803)3.96610620
21gamma-aminobutyric acid transport (GO:0015812)3.95318971
22cellular potassium ion homeostasis (GO:0030007)3.94421687
23exploration behavior (GO:0035640)3.88679641
24regulation of neuronal synaptic plasticity (GO:0048168)3.82681935
25cell communication by electrical coupling (GO:0010644)3.77767148
26neuronal action potential propagation (GO:0019227)3.77326876
27regulation of long-term neuronal synaptic plasticity (GO:0048169)3.74385585
28proline transport (GO:0015824)3.70119009
29glycine transport (GO:0015816)3.66297354
30membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.66124926
31positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.65372255
32dendritic spine morphogenesis (GO:0060997)3.57486269
33protein localization to synapse (GO:0035418)3.49454449
34ionotropic glutamate receptor signaling pathway (GO:0035235)3.49322674
35neuromuscular process controlling balance (GO:0050885)3.46696246
36potassium ion import (GO:0010107)3.35876588
37adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.35277728
38neuromuscular process controlling posture (GO:0050884)3.33679615
39neurotransmitter transport (GO:0006836)3.31585180
40postsynaptic membrane organization (GO:0001941)3.25923057
41dopamine receptor signaling pathway (GO:0007212)3.22820238
42neuron cell-cell adhesion (GO:0007158)3.19696972
43L-amino acid import (GO:0043092)3.18599374
44neurotransmitter-gated ion channel clustering (GO:0072578)3.16644911
45cell communication involved in cardiac conduction (GO:0086065)3.16293636
46amino acid import (GO:0043090)3.15755577
47long-term memory (GO:0007616)3.13907878
48prepulse inhibition (GO:0060134)3.12623408
49cerebellar Purkinje cell layer development (GO:0021680)3.12215097
50regulation of neurotransmitter levels (GO:0001505)3.11618670
51negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.06899931
52positive regulation of synaptic transmission, GABAergic (GO:0032230)3.06162321
53neuronal ion channel clustering (GO:0045161)3.04156677
54synaptic transmission, glutamatergic (GO:0035249)3.03366682
55negative regulation of dendrite morphogenesis (GO:0050774)3.01393261
56regulation of ARF protein signal transduction (GO:0032012)3.00882743
57dendrite morphogenesis (GO:0048813)2.99943415
58vesicle transport along microtubule (GO:0047496)2.98172402
59regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.97876932
60response to parathyroid hormone (GO:0071107)2.97294715
61positive regulation of membrane potential (GO:0045838)2.97174335
62regulation of synapse maturation (GO:0090128)2.97029619
63mating behavior (GO:0007617)2.96928359
64membrane repolarization (GO:0086009)2.95236020
65regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.94452724
66regulation of dendritic spine morphogenesis (GO:0061001)2.94413790
67regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.94186852
68potassium ion homeostasis (GO:0055075)2.94104919
69membrane depolarization during action potential (GO:0086010)2.92682847
70cellular sodium ion homeostasis (GO:0006883)2.92161624
71glutamate receptor signaling pathway (GO:0007215)2.92113727
72positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.91779115
73cerebellar Purkinje cell differentiation (GO:0021702)2.91481304
74membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.89029452
75neuron-neuron synaptic transmission (GO:0007270)2.88225074
76regulation of excitatory postsynaptic membrane potential (GO:0060079)2.87830378
77auditory behavior (GO:0031223)2.87131553
78positive regulation of potassium ion transmembrane transport (GO:1901381)2.85569837
79regulation of synaptic plasticity (GO:0048167)2.85400183
80positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.85345191
81cytoskeletal anchoring at plasma membrane (GO:0007016)2.78590717
82transmission of nerve impulse (GO:0019226)2.77733667
83regulation of membrane repolarization (GO:0060306)2.77022188
84cellular response to catecholamine stimulus (GO:0071870)2.76823259
85cellular response to monoamine stimulus (GO:0071868)2.76823259
86response to auditory stimulus (GO:0010996)2.75104160
87positive regulation of synapse maturation (GO:0090129)2.74775552
88alanine transport (GO:0032328)2.74471977
89regulation of neurotransmitter secretion (GO:0046928)2.74103160
90regulation of postsynaptic membrane potential (GO:0060078)2.73722930
91regulation of NFAT protein import into nucleus (GO:0051532)2.73343296
92cell migration in hindbrain (GO:0021535)2.71287387
93regulation of clathrin-mediated endocytosis (GO:2000369)2.71218187
94neuromuscular process (GO:0050905)2.71000145
95positive regulation of dendritic spine development (GO:0060999)2.70060209
96synaptic vesicle endocytosis (GO:0048488)2.69581163
97regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.66221641
98establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.66036939
99mitochondrion transport along microtubule (GO:0047497)2.66036939
100establishment of mitochondrion localization (GO:0051654)2.65652176
101positive regulation of potassium ion transport (GO:0043268)2.65456592
102G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.64801307
103cell-cell junction maintenance (GO:0045217)2.64502027
104negative regulation of microtubule polymerization (GO:0031115)2.64181686
105organelle transport along microtubule (GO:0072384)2.61229293
106axon cargo transport (GO:0008088)2.60312944
107axon ensheathment in central nervous system (GO:0032291)2.59953793
108central nervous system myelination (GO:0022010)2.59953793
109negative regulation of potassium ion transmembrane transport (GO:1901380)2.58429070
110membrane repolarization during action potential (GO:0086011)2.58175894
111membrane hyperpolarization (GO:0060081)2.58068413
112adherens junction assembly (GO:0034333)2.57928746
113regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.57750093
114regulation of neurotransmitter transport (GO:0051588)2.57124554
115positive regulation of neurotransmitter transport (GO:0051590)2.56457371
116intraspecies interaction between organisms (GO:0051703)2.55573763
117social behavior (GO:0035176)2.55573763
118regulation of early endosome to late endosome transport (GO:2000641)2.55532567
119axonal fasciculation (GO:0007413)2.54939450
120plasma membrane repair (GO:0001778)2.54802877
121apical protein localization (GO:0045176)2.54746842
122regulation of vesicle fusion (GO:0031338)2.54619925
123membrane depolarization (GO:0051899)2.54107851
124focal adhesion assembly (GO:0048041)2.51754167
125cell-substrate adherens junction assembly (GO:0007045)2.51754167
126camera-type eye morphogenesis (GO:0048593)2.49045517
127* neuron recognition (GO:0008038)2.47646257
128positive regulation of dendritic spine morphogenesis (GO:0061003)2.47456360
129cell differentiation in hindbrain (GO:0021533)2.46737090
130regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.43067830
131regulation of voltage-gated calcium channel activity (GO:1901385)2.41061796
132dendritic spine organization (GO:0097061)2.39776011
133planar cell polarity pathway involved in neural tube closure (GO:0090179)2.38828552
134protein targeting to plasma membrane (GO:0072661)2.36286472
135peripheral nervous system axon ensheathment (GO:0032292)2.35923254
136myelination in peripheral nervous system (GO:0022011)2.35923254
137peptidyl-tyrosine autophosphorylation (GO:0038083)2.35485659

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.89786035
2SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.71691870
3RARB_27405468_Chip-Seq_BRAIN_Mouse2.70691789
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.64603537
5DROSHA_22980978_ChIP-Seq_HELA_Human2.59087758
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.54087282
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.54087282
8JARID2_20064375_ChIP-Seq_MESCs_Mouse2.52189079
9EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.42503936
10MTF2_20144788_ChIP-Seq_MESCs_Mouse2.40341899
11* REST_21632747_ChIP-Seq_MESCs_Mouse2.39982219
12SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.38532817
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.35329502
14MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.34241601
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.21978134
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.14699574
17EZH2_27294783_Chip-Seq_ESCs_Mouse2.14481699
18SUZ12_27294783_Chip-Seq_ESCs_Mouse2.11541782
19* REST_18959480_ChIP-ChIP_MESCs_Mouse2.10759898
20ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.10358813
21SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.06953740
22EZH2_27304074_Chip-Seq_ESCs_Mouse2.04014684
23ERG_21242973_ChIP-ChIP_JURKAT_Human1.97927364
24NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.94621845
25RNF2_27304074_Chip-Seq_ESCs_Mouse1.93307140
26NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.82010524
27EED_16625203_ChIP-ChIP_MESCs_Mouse1.80398203
28GBX2_23144817_ChIP-Seq_PC3_Human1.80048084
29IKZF1_21737484_ChIP-ChIP_HCT116_Human1.78319421
30CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.76060493
31ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.73613802
32RACK7_27058665_Chip-Seq_MCF-7_Human1.68496523
33* KDM2B_26808549_Chip-Seq_K562_Human1.62616595
34* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.61992336
35TCF7_22412390_ChIP-Seq_EML_Mouse1.59412147
36DNAJC2_21179169_ChIP-ChIP_NT2_Human1.56798835
37KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.56179583
38TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.53413632
39* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.50599218
40TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.48344005
41ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.47272561
42TP63_17297297_ChIP-ChIP_HaCaT_Human1.44892208
43WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.41879723
44AR_21572438_ChIP-Seq_LNCaP_Human1.41249370
45CLOCK_20551151_ChIP-Seq_293T_Human1.39244257
46RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.39097353
47RARG_19884340_ChIP-ChIP_MEFs_Mouse1.35739274
48RING1B_27294783_Chip-Seq_ESCs_Mouse1.34386780
49WT1_25993318_ChIP-Seq_PODOCYTE_Human1.33971900
50ESR1_21235772_ChIP-Seq_MCF-7_Human1.31237181
51UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.28465730
52GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.26072134
53P300_27058665_Chip-Seq_ZR-75-30cells_Human1.24414619
54TP53_20018659_ChIP-ChIP_R1E_Mouse1.23196116
55GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.19565543
56TRIM28_21343339_ChIP-Seq_HEK293_Human1.19069919
57KDM2B_26808549_Chip-Seq_SUP-B15_Human1.18325594
58TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.18191073
59MYC_22102868_ChIP-Seq_BL_Human1.18095019
60CTCF_27219007_Chip-Seq_Bcells_Human1.18094550
61NR3C1_23031785_ChIP-Seq_PC12_Mouse1.17665581
62ZNF274_21170338_ChIP-Seq_K562_Hela1.17492155
63* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.17350268
64AR_19668381_ChIP-Seq_PC3_Human1.16532828
65ELK3_25401928_ChIP-Seq_HUVEC_Human1.14841386
66SRY_22984422_ChIP-ChIP_TESTIS_Rat1.14687191
67SOX2_21211035_ChIP-Seq_LN229_Gbm1.14442710
68SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.13078879
69TET1_21451524_ChIP-Seq_MESCs_Mouse1.13049958
70THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.12890318
71* LXR_22292898_ChIP-Seq_THP-1_Human1.11803865
72ESR1_20079471_ChIP-ChIP_T-47D_Human1.11473409
73ESR2_21235772_ChIP-Seq_MCF-7_Human1.10309692
74* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.10150533
75PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.09852154
76P68_20966046_ChIP-Seq_HELA_Human1.09319141
77SMAD4_21799915_ChIP-Seq_A2780_Human1.09088854
78CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.08590491
79RUNX1_27514584_Chip-Seq_MCF-7_Human1.08214593
80CDX2_19796622_ChIP-Seq_MESCs_Mouse1.06939090
81DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.06828099
82* RING1B_27294783_Chip-Seq_NPCs_Mouse1.06114265
83MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.05398780
84CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.03683612
85ZNF263_19887448_ChIP-Seq_K562_Human1.02993560
86SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.02854570
87* TET1_21490601_ChIP-Seq_MESCs_Mouse1.02721439
88RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.02202939
89SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.01506734
90NFIB_24661679_ChIP-Seq_LUNG_Mouse1.01176823
91ZNF217_24962896_ChIP-Seq_MCF-7_Human1.00319942
92* SA1_27219007_Chip-Seq_ERYTHROID_Human1.00000732
93SMAD4_21741376_ChIP-Seq_HESCs_Human0.99151055
94EP300_21415370_ChIP-Seq_HL-1_Mouse0.98968668
95KDM2B_26808549_Chip-Seq_DND41_Human0.98968359
96SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.98068733
97CTBP2_25329375_ChIP-Seq_LNCAP_Human0.97837612
98POU5F1_16518401_ChIP-PET_MESCs_Mouse0.97833148
99NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.97779651
100BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.97774627
101ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.97707775
102SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.97393314
103ESR1_15608294_ChIP-ChIP_MCF-7_Human0.97358552
104CTNNB1_20460455_ChIP-Seq_HCT116_Human0.96129026
105* CTCF_27219007_Chip-Seq_ERYTHROID_Human0.96067518
106KLF4_19829295_ChIP-Seq_ESCs_Human0.95817254
107STAT6_21828071_ChIP-Seq_BEAS2B_Human0.94903185
108GATA1_26923725_Chip-Seq_HPCs_Mouse0.94458559
109NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.94454758
110SMC4_20622854_ChIP-Seq_HELA_Human0.94287829
111STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.93889406
112RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.93162082
113VDR_21846776_ChIP-Seq_THP-1_Human0.92571887
114* KDM2B_26808549_Chip-Seq_JURKAT_Human0.92427340
115CREB1_26743006_Chip-Seq_LNCaP_Human0.91519698
116TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.91439643
117PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.90301754
118SMAD3_21741376_ChIP-Seq_HESCs_Human0.89677766
119AHR_22903824_ChIP-Seq_MCF-7_Human0.89480590
120SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88789635
121TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.87609014
122STAT3_23295773_ChIP-Seq_U87_Human0.86602798
123MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.85877891
124OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.85365341
125CTBP1_25329375_ChIP-Seq_LNCAP_Human0.85238238
126PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.84058047
127* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.83963990
128CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.83818334
129SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.82618061
130SMAD3_21741376_ChIP-Seq_ESCs_Human0.82351315
131OCT4_19829295_ChIP-Seq_ESCs_Human0.82240573
132ARNT_22903824_ChIP-Seq_MCF-7_Human0.81408250
133TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.81184651
134EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.80852410
135FOXA2_19822575_ChIP-Seq_HepG2_Human0.80373905
136P53_22127205_ChIP-Seq_FIBROBLAST_Human0.77753869
137RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.77508043

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.02950433
2MP0003635_abnormal_synaptic_transmissio3.75517685
3MP0003880_abnormal_central_pattern3.45879006
4MP0004270_analgesia3.40824508
5MP0002822_catalepsy3.03772257
6MP0009745_abnormal_behavioral_response2.91900138
7MP0002063_abnormal_learning/memory/cond2.88209137
8MP0002064_seizures2.74591080
9MP0003705_abnormal_hypodermis_morpholog2.63146642
10MP0003123_paternal_imprinting2.60026551
11MP0009046_muscle_twitch2.59748959
12MP0002909_abnormal_adrenal_gland2.52468622
13MP0005423_abnormal_somatic_nervous2.46571489
14MP0001968_abnormal_touch/_nociception2.36829415
15MP0009780_abnormal_chondrocyte_physiolo2.33316450
16MP0002734_abnormal_mechanical_nocicepti2.27638221
17MP0002572_abnormal_emotion/affect_behav2.27287355
18MP0005409_darkened_coat_color2.24493074
19MP0002272_abnormal_nervous_system2.23172483
20MP0001486_abnormal_startle_reflex2.17358995
21MP0003329_amyloid_beta_deposits2.07280017
22MP0000751_myopathy2.01863623
23MP0004858_abnormal_nervous_system2.01241551
24MP0001348_abnormal_lacrimal_gland1.96478551
25MP0002733_abnormal_thermal_nociception1.90383280
26MP0001501_abnormal_sleep_pattern1.89508227
27MP0008569_lethality_at_weaning1.82825173
28MP0002837_dystrophic_cardiac_calcinosis1.80448098
29MP0001440_abnormal_grooming_behavior1.76373590
30MP0004885_abnormal_endolymph1.73532342
31MP0001970_abnormal_pain_threshold1.72587376
32MP0003283_abnormal_digestive_organ1.71931705
33MP0004811_abnormal_neuron_physiology1.65913091
34MP0002736_abnormal_nociception_after1.63224861
35MP0002067_abnormal_sensory_capabilities1.59685366
36MP0008961_abnormal_basal_metabolism1.56341162
37MP0002735_abnormal_chemical_nociception1.54817045
38MP0004924_abnormal_behavior1.50529950
39MP0005386_behavior/neurological_phenoty1.50529950
40MP0000566_synostosis1.48305194
41MP0000955_abnormal_spinal_cord1.47787902
42MP0004145_abnormal_muscle_electrophysio1.45004292
43MP0002557_abnormal_social/conspecific_i1.43517771
44MP0002184_abnormal_innervation1.42920559
45MP0003879_abnormal_hair_cell1.41995662
46MP0000013_abnormal_adipose_tissue1.40580441
47MP0003633_abnormal_nervous_system1.38161144
48MP0004130_abnormal_muscle_cell1.36161564
49MP0002089_abnormal_postnatal_growth/wei1.32892543
50MP0002066_abnormal_motor_capabilities/c1.32222030
51MP0000579_abnormal_nail_morphology1.32192968
52MP0000778_abnormal_nervous_system1.29050539
53MP0000537_abnormal_urethra_morphology1.25949307
54MP0004215_abnormal_myocardial_fiber1.25871126
55MP0009672_abnormal_birth_weight1.23498748
56MP0009379_abnormal_foot_pigmentation1.23309493
57MP0002882_abnormal_neuron_morphology1.22428634
58MP0004043_abnormal_pH_regulation1.22193304
59MP0001346_abnormal_lacrimal_gland1.21632169
60MP0005646_abnormal_pituitary_gland1.19503927
61MP0005076_abnormal_cell_differentiation1.19400953
62MP0001984_abnormal_olfaction1.19206124
63MP0003646_muscle_fatigue1.18248186
64MP0004185_abnormal_adipocyte_glucose1.18245425
65MP0006276_abnormal_autonomic_nervous1.18207766
66MP0002249_abnormal_larynx_morphology1.17050758
67MP0003690_abnormal_glial_cell1.16820116
68MP0004085_abnormal_heartbeat1.12980206
69MP0010234_abnormal_vibrissa_follicle1.12882366
70MP0005167_abnormal_blood-brain_barrier1.12372658
71MP0000534_abnormal_ureter_morphology1.11495675
72MP0005535_abnormal_body_temperature1.09395699
73MP0003137_abnormal_impulse_conducting1.08799868
74MP0003631_nervous_system_phenotype1.07507892
75MP0005623_abnormal_meninges_morphology1.07443796
76MP0001849_ear_inflammation1.06597036
77MP0000747_muscle_weakness1.06113390
78MP0004233_abnormal_muscle_weight1.05466069
79MP0004036_abnormal_muscle_relaxation1.03966097
80MP0003075_altered_response_to1.03691311
81MP0003861_abnormal_nervous_system1.01021761
82MP0004084_abnormal_cardiac_muscle0.99917324
83MP0005666_abnormal_adipose_tissue0.99917146
84MP0008874_decreased_physiological_sensi0.97656110
85MP0000604_amyloidosis0.95574296
86MP0001502_abnormal_circadian_rhythm0.94259807
87MP0002229_neurodegeneration0.94029460
88MP0002152_abnormal_brain_morphology0.93800015
89MP0002069_abnormal_eating/drinking_beha0.92757901
90MP0008872_abnormal_physiological_respon0.92000258
91MP0003942_abnormal_urinary_system0.91834020
92MP0004142_abnormal_muscle_tone0.89610134
93MP0003122_maternal_imprinting0.89482724
94MP0005187_abnormal_penis_morphology0.88143890
95MP0003634_abnormal_glial_cell0.87917370
96MP0005451_abnormal_body_composition0.87086259
97MP0005645_abnormal_hypothalamus_physiol0.84969654
98MP0000759_abnormal_skeletal_muscle0.84474512
99MP0001188_hyperpigmentation0.83330039
100MP0004087_abnormal_muscle_fiber0.82133081
101MP0005620_abnormal_muscle_contractility0.81586135
102MP0003787_abnormal_imprinting0.81218802
103MP0004484_altered_response_of0.81094579
104MP0001177_atelectasis0.79466521
105MP0005375_adipose_tissue_phenotype0.78984950
106MP0000920_abnormal_myelination0.78642700
107MP0003938_abnormal_ear_development0.78455720
108MP0010630_abnormal_cardiac_muscle0.78059433
109MP0002081_perinatal_lethality0.77293245
110MP0002090_abnormal_vision0.76985369
111MP0000003_abnormal_adipose_tissue0.75261413
112MP0005085_abnormal_gallbladder_physiolo0.75045991
113MP0002269_muscular_atrophy0.75025776
114MP0000462_abnormal_digestive_system0.74145773
115MP0003632_abnormal_nervous_system0.73334067
116MP0001943_abnormal_respiration0.72185316
117MP0005330_cardiomyopathy0.71871030
118MP0002139_abnormal_hepatobiliary_system0.71713972
119MP0010769_abnormal_survival0.70643598
120MP0002972_abnormal_cardiac_muscle0.69878213
121MP0004510_myositis0.68813641
122MP0001299_abnormal_eye_distance/0.68450014
123MP0004742_abnormal_vestibular_system0.68316056
124MP0003172_abnormal_lysosome_physiology0.68281781
125MP0002234_abnormal_pharynx_morphology0.68228671
126MP0004264_abnormal_extraembryonic_tissu0.67636045
127MP0005257_abnormal_intraocular_pressure0.66599450
128MP0002078_abnormal_glucose_homeostasis0.66498254
129MP0000749_muscle_degeneration0.66212508
130MP0010768_mortality/aging0.65195545
131MP0010770_preweaning_lethality0.64961019
132MP0002082_postnatal_lethality0.64961019
133MP0002796_impaired_skin_barrier0.64810549
134MP0005360_urolithiasis0.64149518
135MP0001485_abnormal_pinna_reflex0.60021280
136MP0005083_abnormal_biliary_tract0.59213445

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)6.03468935
2Focal motor seizures (HP:0011153)5.07822380
3Visual hallucinations (HP:0002367)4.67011414
4Focal seizures (HP:0007359)4.28612214
5Obstructive sleep apnea (HP:0002870)4.00311115
6Action tremor (HP:0002345)3.90158217
7Ventricular fibrillation (HP:0001663)3.74076530
8Supranuclear gaze palsy (HP:0000605)3.59523649
9Ankle clonus (HP:0011448)3.42351073
10Bundle branch block (HP:0011710)3.34037922
11Abnormality of the lower motor neuron (HP:0002366)3.23948905
12Depression (HP:0000716)3.23841152
13Generalized tonic-clonic seizures (HP:0002069)3.10743762
14Atonic seizures (HP:0010819)3.05951375
15Progressive cerebellar ataxia (HP:0002073)3.03727346
16Absence seizures (HP:0002121)2.98169580
17Postural instability (HP:0002172)2.97609832
18Papilledema (HP:0001085)2.94221274
19Poor eye contact (HP:0000817)2.89863491
20Impaired social interactions (HP:0000735)2.88997908
21Abnormal social behavior (HP:0012433)2.88997908
22Impaired vibration sensation in the lower limbs (HP:0002166)2.88818119
23Anxiety (HP:0000739)2.85281882
24Dysdiadochokinesis (HP:0002075)2.82933304
25Torticollis (HP:0000473)2.77679909
26Epileptic encephalopathy (HP:0200134)2.74884945
27Insomnia (HP:0100785)2.73899004
28Urinary bladder sphincter dysfunction (HP:0002839)2.71678641
29Urinary urgency (HP:0000012)2.68535578
30Pheochromocytoma (HP:0002666)2.65197084
31Dysmetric saccades (HP:0000641)2.63223632
32Abnormality of binocular vision (HP:0011514)2.60875847
33Diplopia (HP:0000651)2.60875847
34Dialeptic seizures (HP:0011146)2.59560518
35Exercise-induced myalgia (HP:0003738)2.59412577
36Febrile seizures (HP:0002373)2.58989747
37Cerebral inclusion bodies (HP:0100314)2.57761403
38Dysmetria (HP:0001310)2.56674411
39Mutism (HP:0002300)2.55844595
40Sudden death (HP:0001699)2.55170037
41Hemiplegia (HP:0002301)2.54752193
42Intention tremor (HP:0002080)2.52582548
43Termporal pattern (HP:0011008)2.50462478
44Insidious onset (HP:0003587)2.50462478
45Abnormal eating behavior (HP:0100738)2.47169514
46Neurofibrillary tangles (HP:0002185)2.46730446
47Focal dystonia (HP:0004373)2.45211071
48Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.39211892
49Bronchomalacia (HP:0002780)2.31964398
50Craniofacial dystonia (HP:0012179)2.31950221
51Spastic gait (HP:0002064)2.31948399
52Aplasia involving bones of the extremities (HP:0009825)2.31254584
53Aplasia involving bones of the upper limbs (HP:0009823)2.31254584
54Aplasia of the phalanges of the hand (HP:0009802)2.31254584
55Prolonged QT interval (HP:0001657)2.30980171
56Hyporeflexia of lower limbs (HP:0002600)2.30099313
57Resting tremor (HP:0002322)2.29122213
58Genetic anticipation (HP:0003743)2.28002000
59Foot dorsiflexor weakness (HP:0009027)2.27286366
60Annular pancreas (HP:0001734)2.25512096
61Truncal ataxia (HP:0002078)2.25308693
62Megalencephaly (HP:0001355)2.25008016
63Heart block (HP:0012722)2.24773736
64Status epilepticus (HP:0002133)2.23318969
65Broad-based gait (HP:0002136)2.22876653
66Hyperparathyroidism (HP:0000843)2.22061931
67Abnormal EKG (HP:0003115)2.20567423
68Rapidly progressive (HP:0003678)2.18742539
69Akinesia (HP:0002304)2.18395928
70Bradykinesia (HP:0002067)2.17542526
71Overriding aorta (HP:0002623)2.16908078
72Abnormality of the foot musculature (HP:0001436)2.16140704
73Shallow orbits (HP:0000586)2.14704819
74Gaze-evoked nystagmus (HP:0000640)2.14532842
75Pointed chin (HP:0000307)2.14292626
76Centrally nucleated skeletal muscle fibers (HP:0003687)2.14250419
77Agitation (HP:0000713)2.14174227
78Amblyopia (HP:0000646)2.12788304
79Neuroendocrine neoplasm (HP:0100634)2.12719761
80Syncope (HP:0001279)2.12498459
81Atrioventricular block (HP:0001678)2.09364207
82Hypercortisolism (HP:0001578)2.08528962
83Postural tremor (HP:0002174)2.06744052
84Sleep apnea (HP:0010535)2.05776818
85Lower limb muscle weakness (HP:0007340)2.04979767
86Abnormal atrioventricular conduction (HP:0005150)2.03439287
87Hyperacusis (HP:0010780)2.02819289
88Bowel incontinence (HP:0002607)2.01202427
89Scanning speech (HP:0002168)2.00945869
90Difficulty running (HP:0009046)2.00544570
91Neoplasm of the peripheral nervous system (HP:0100007)2.00260832
92Ventricular arrhythmia (HP:0004308)1.99997237
93Clonus (HP:0002169)1.99615137
94Distal lower limb muscle weakness (HP:0009053)1.99389642
95Peripheral hypomyelination (HP:0007182)1.99035940
96Impaired smooth pursuit (HP:0007772)1.98807854
97Myotonia (HP:0002486)1.98571715
98Hemiparesis (HP:0001269)1.98239220
99Hyperthyroidism (HP:0000836)1.95334945
100Elfin facies (HP:0004428)1.95177056
101Neuronal loss in central nervous system (HP:0002529)1.94252329
102Progressive inability to walk (HP:0002505)1.94105156
103Distal lower limb amyotrophy (HP:0008944)1.92485550
104Achilles tendon contracture (HP:0001771)1.91255049
105Impaired vibratory sensation (HP:0002495)1.91005315
106Germ cell neoplasia (HP:0100728)1.90964453
107Abnormality of the Achilles tendon (HP:0005109)1.89587429
108Abnormality of the corticospinal tract (HP:0002492)1.88389583
109Precocious puberty (HP:0000826)1.88334707
110Type 1 muscle fiber predominance (HP:0003803)1.88211572
111Hammertoe (HP:0001765)1.87771637
112Lower limb asymmetry (HP:0100559)1.87610946
113Macroorchidism (HP:0000053)1.86932757
114Distal upper limb amyotrophy (HP:0007149)1.84665383
115Upper limb amyotrophy (HP:0009129)1.84665383
116Myopathic facies (HP:0002058)1.83680105
117Tetraplegia (HP:0002445)1.82203836
118Renovascular hypertension (HP:0100817)1.82126552
119Exercise-induced muscle cramps (HP:0003710)1.81877603
120Limb dystonia (HP:0002451)1.81344651
121Ketoacidosis (HP:0001993)1.80756830
122Hypsarrhythmia (HP:0002521)1.80621291
123Apathy (HP:0000741)1.80164807
124Arnold-Chiari malformation (HP:0002308)1.80003666
125Stereotypic behavior (HP:0000733)1.79945542
126Lower limb amyotrophy (HP:0007210)1.79340237
127Drooling (HP:0002307)1.79235208
128Excessive salivation (HP:0003781)1.79235208
129EEG with generalized epileptiform discharges (HP:0011198)1.79146833
130Neoplasm of the heart (HP:0100544)1.78932679
131Fetal akinesia sequence (HP:0001989)1.78222508
132Turricephaly (HP:0000262)1.77962104
133Abnormality of ocular smooth pursuit (HP:0000617)1.77687789
134Abnormal large intestine physiology (HP:0012700)1.77027084
135Long palpebral fissure (HP:0000637)1.75596189
136Asymmetry of the thorax (HP:0001555)1.75331632
137Renal duplication (HP:0000075)1.74786314
138Decreased motor nerve conduction velocity (HP:0003431)1.74249261
139Abnormality of the left ventricular outflow tract (HP:0011103)1.73444003
140Subaortic stenosis (HP:0001682)1.73444003
141Increased variability in muscle fiber diameter (HP:0003557)1.73238827
142EMG: neuropathic changes (HP:0003445)1.73070244
143Partial duplication of thumb phalanx (HP:0009944)1.70540226
144Deep palmar crease (HP:0006191)1.70406661
145Hypercalcemia (HP:0003072)1.68790717
146Muscle fiber inclusion bodies (HP:0100299)1.66947167

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K93.70362911
2NTRK33.59404142
3EPHA43.24381893
4PRKD32.77261934
5MARK12.61419510
6MAP3K42.56715059
7KSR22.55316051
8PAK62.43120910
9MINK12.41293783
10DAPK22.39718294
11CAMKK12.12197411
12NTRK12.04802584
13EEF2K1.95933898
14LMTK21.92461348
15TRIB31.90768834
16SIK11.90683171
17MAP2K41.89891705
18STK381.86259516
19PHKG11.84539973
20PHKG21.84539973
21SMG11.74013586
22TYRO31.71944760
23NTRK21.70486165
24MAP3K21.60824332
25CDK121.59642575
26MAP2K71.54028631
27LATS21.52083620
28TAOK11.48056461
29RIPK11.41799141
30PINK11.40772408
31CASK1.36895203
32CDK51.36517687
33TTN1.31700489
34NEK11.29941931
35RET1.28363910
36UHMK11.28055308
37MAP3K101.27372954
38ALK1.24007201
39KSR11.21642470
40PKN21.19418065
41PRKCH1.18890341
42GRK51.15577758
43SIK21.15345873
44FGFR41.13497552
45PAK31.08829183
46WNK11.04344870
47FES1.03892237
48STK110.99670053
49MAPK120.97238536
50PRKCG0.94207519
51MAP3K10.92954756
52PDGFRA0.92950647
53DAPK10.88982086
54ICK0.88902626
55ARAF0.86551059
56SGK4940.82705464
57SGK2230.82705464
58MTOR0.82286635
59NEK60.82197560
60CAMKK20.82140881
61SCYL20.82115317
62CDC42BPA0.81945555
63PNCK0.81175546
64PDPK10.81017030
65CAMK1G0.80491375
66CAMK10.80429091
67BRAF0.79646999
68RIPK40.79269640
69SGK30.78625806
70MAP3K70.76251797
71CAMK1D0.76076231
72WNK40.75807249
73PDK10.75057797
74MAP3K120.75001200
75PDK40.74543283
76PDK30.74543283
77CAMK2A0.72112125
78CDK140.70832179
79CDK150.70727763
80DMPK0.69954454
81PIK3CA0.69846358
82TESK10.68810176
83CDK180.66788167
84MARK20.66033116
85MAPK130.65257687
86EPHA20.62851755
87PLK20.61991118
88MAP3K110.61047347
89DYRK1A0.60782346
90FGFR20.60339950
91CDK11A0.60329126
92DDR20.58893288
93MAP3K130.58478671
94CDK190.58161934
95SGK10.57372171
96PTK60.57351823
97BRD40.55719026
98FER0.55456179
99MAP2K20.55405880
100ROCK20.55164536
101RPS6KA30.54627285
102PRKCZ0.54610706
103SGK20.53104516
104MAP2K10.52870178
105PTK2B0.51658749
106CSNK1G20.51100274
107CAMK40.50798347
108PRKD10.50295141
109DYRK1B0.50079481
110BMX0.48293849
111CAMK2G0.47824945
112CAMK2D0.47660879
113CAMK2B0.47211912
114ROCK10.45088803
115MAPK100.43936638
116RAF10.43678776
117RPS6KB20.43534970
118RPS6KB10.42593485
119DAPK30.42410411
120FYN0.42281265
121RPS6KA20.41934845
122PRKAA10.41593859
123EPHB20.41230364
124PDGFRB0.40057921
125HIPK20.40003307
126PTK20.39046924
127PRPF4B0.38837609
128TNK20.38552697
129OXSR10.37835813
130AKT20.36300552

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009102.85822225
2Synaptic vesicle cycle_Homo sapiens_hsa047212.66795629
3Olfactory transduction_Homo sapiens_hsa047402.36240127
4Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.35966163
5Nicotine addiction_Homo sapiens_hsa050332.33954456
6GABAergic synapse_Homo sapiens_hsa047272.26108399
7Circadian entrainment_Homo sapiens_hsa047132.11497398
8Long-term potentiation_Homo sapiens_hsa047202.06356368
9Glutamatergic synapse_Homo sapiens_hsa047241.98650604
10Insulin secretion_Homo sapiens_hsa049111.93370331
11Amphetamine addiction_Homo sapiens_hsa050311.90580227
12Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.88012720
13Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.85902359
14Morphine addiction_Homo sapiens_hsa050321.85384482
15Gastric acid secretion_Homo sapiens_hsa049711.80209202
16Salivary secretion_Homo sapiens_hsa049701.77055046
17Dopaminergic synapse_Homo sapiens_hsa047281.76858558
18Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.75188817
19Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.70194128
20Aldosterone synthesis and secretion_Homo sapiens_hsa049251.64684649
21Cholinergic synapse_Homo sapiens_hsa047251.63878889
22Cocaine addiction_Homo sapiens_hsa050301.47833077
23* Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.43390908
24Type II diabetes mellitus_Homo sapiens_hsa049301.42991975
25Renin secretion_Homo sapiens_hsa049241.40443310
26Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.40193699
27Oxytocin signaling pathway_Homo sapiens_hsa049211.36621430
28GnRH signaling pathway_Homo sapiens_hsa049121.30031664
29Taste transduction_Homo sapiens_hsa047421.26033234
30Arginine biosynthesis_Homo sapiens_hsa002201.23055876
31Bile secretion_Homo sapiens_hsa049761.22799134
32Gap junction_Homo sapiens_hsa045401.19344398
33Long-term depression_Homo sapiens_hsa047301.17515857
34Calcium signaling pathway_Homo sapiens_hsa040201.17474118
35Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.15223525
36Estrogen signaling pathway_Homo sapiens_hsa049151.13524432
37Cardiac muscle contraction_Homo sapiens_hsa042601.12800460
38cAMP signaling pathway_Homo sapiens_hsa040241.10166048
39Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.06420323
40Glioma_Homo sapiens_hsa052141.02940448
41Butanoate metabolism_Homo sapiens_hsa006501.02801471
42Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.02019770
43Vitamin B6 metabolism_Homo sapiens_hsa007501.01394083
44Dorso-ventral axis formation_Homo sapiens_hsa043201.01307161
45Serotonergic synapse_Homo sapiens_hsa047260.99929783
46Dilated cardiomyopathy_Homo sapiens_hsa054140.99622286
472-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.98019629
48cGMP-PKG signaling pathway_Homo sapiens_hsa040220.97436048
49Chronic myeloid leukemia_Homo sapiens_hsa052200.97299066
50Thyroid cancer_Homo sapiens_hsa052160.96893548
51Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.93755852
52Carbohydrate digestion and absorption_Homo sapiens_hsa049730.91779986
53Phosphatidylinositol signaling system_Homo sapiens_hsa040700.90637329
54Thyroid hormone synthesis_Homo sapiens_hsa049180.88092788
55Melanogenesis_Homo sapiens_hsa049160.87170897
56Pancreatic secretion_Homo sapiens_hsa049720.86591672
57Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.86010346
58Adherens junction_Homo sapiens_hsa045200.85552882
59Glucagon signaling pathway_Homo sapiens_hsa049220.85020452
60Tight junction_Homo sapiens_hsa045300.84672242
61Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.84026034
62Notch signaling pathway_Homo sapiens_hsa043300.82423014
63Vascular smooth muscle contraction_Homo sapiens_hsa042700.78811243
64ErbB signaling pathway_Homo sapiens_hsa040120.78030783
65Phospholipase D signaling pathway_Homo sapiens_hsa040720.77014600
66Axon guidance_Homo sapiens_hsa043600.75451238
67Hippo signaling pathway_Homo sapiens_hsa043900.73309876
68mTOR signaling pathway_Homo sapiens_hsa041500.73246541
69Insulin signaling pathway_Homo sapiens_hsa049100.72949155
70Prolactin signaling pathway_Homo sapiens_hsa049170.72633848
71Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.69839108
72Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.68922603
73Colorectal cancer_Homo sapiens_hsa052100.66235372
74Wnt signaling pathway_Homo sapiens_hsa043100.65184003
75Thyroid hormone signaling pathway_Homo sapiens_hsa049190.65125239
76Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.64181280
77Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.62768333
78VEGF signaling pathway_Homo sapiens_hsa043700.62195904
79Collecting duct acid secretion_Homo sapiens_hsa049660.62098913
80Prion diseases_Homo sapiens_hsa050200.61612892
81Oocyte meiosis_Homo sapiens_hsa041140.61230123
82Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.61158227
83Acute myeloid leukemia_Homo sapiens_hsa052210.61101668
84AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.59737915
85Neurotrophin signaling pathway_Homo sapiens_hsa047220.59138690
86Longevity regulating pathway - mammal_Homo sapiens_hsa042110.58778673
87Proteoglycans in cancer_Homo sapiens_hsa052050.58426523
88Arginine and proline metabolism_Homo sapiens_hsa003300.58196177
89Fatty acid biosynthesis_Homo sapiens_hsa000610.58114366
90Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.57775941
91Pancreatic cancer_Homo sapiens_hsa052120.57116490
92Focal adhesion_Homo sapiens_hsa045100.55986898
93Choline metabolism in cancer_Homo sapiens_hsa052310.55284899
94Endometrial cancer_Homo sapiens_hsa052130.54411447
95Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.53860364
96Primary bile acid biosynthesis_Homo sapiens_hsa001200.53644923
97Insulin resistance_Homo sapiens_hsa049310.48950965
98Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.48860998
99Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.47989836
100MAPK signaling pathway_Homo sapiens_hsa040100.47841636
101Phenylalanine metabolism_Homo sapiens_hsa003600.47387704
102Fatty acid metabolism_Homo sapiens_hsa012120.46957916
103Propanoate metabolism_Homo sapiens_hsa006400.46111932
104Central carbon metabolism in cancer_Homo sapiens_hsa052300.46106206
105Adipocytokine signaling pathway_Homo sapiens_hsa049200.45942410
106Endocytosis_Homo sapiens_hsa041440.45807983
107Non-small cell lung cancer_Homo sapiens_hsa052230.45624176
108Fatty acid degradation_Homo sapiens_hsa000710.45604812
109Renal cell carcinoma_Homo sapiens_hsa052110.45326969
110Vibrio cholerae infection_Homo sapiens_hsa051100.44629505
111AMPK signaling pathway_Homo sapiens_hsa041520.43347680
112Rap1 signaling pathway_Homo sapiens_hsa040150.41754280
113PPAR signaling pathway_Homo sapiens_hsa033200.41163193
114Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.40824005
115Ovarian steroidogenesis_Homo sapiens_hsa049130.37952301
116Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.36861572
117Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.35118615
118Ras signaling pathway_Homo sapiens_hsa040140.35081051
119Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.34781418
120Inositol phosphate metabolism_Homo sapiens_hsa005620.34762634
121Sphingolipid signaling pathway_Homo sapiens_hsa040710.34392927

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