DRAXIN

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)7.20573421
2central nervous system projection neuron axonogenesis (GO:0021952)6.15734050
3behavioral response to nicotine (GO:0035095)5.88917450
4lateral sprouting from an epithelium (GO:0060601)5.83241965
5nucleobase catabolic process (GO:0046113)5.38948046
6layer formation in cerebral cortex (GO:0021819)5.28615178
7cell migration in hindbrain (GO:0021535)5.14027868
8presynaptic membrane assembly (GO:0097105)5.06379118
9cerebral cortex radially oriented cell migration (GO:0021799)4.87054060
10axonal fasciculation (GO:0007413)4.83868365
11central nervous system neuron axonogenesis (GO:0021955)4.56341345
12dendrite morphogenesis (GO:0048813)4.53071781
13spinal cord development (GO:0021510)4.52673577
14limb bud formation (GO:0060174)4.36270309
15glial cell proliferation (GO:0014009)4.32364310
16neuron recognition (GO:0008038)4.21506773
17hindbrain development (GO:0030902)4.14877858
18planar cell polarity pathway involved in neural tube closure (GO:0090179)3.99596947
19neuron cell-cell adhesion (GO:0007158)3.93850470
20cerebellum development (GO:0021549)3.86084532
21negative regulation of catenin import into nucleus (GO:0035414)3.81213845
22dendritic spine morphogenesis (GO:0060997)3.79354378
23regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.77170318
24head development (GO:0060322)3.72875375
25transmission of nerve impulse (GO:0019226)3.69465114
26regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.68162564
27neuron migration (GO:0001764)3.67085125
28proximal/distal pattern formation (GO:0009954)3.65426435
29axon extension (GO:0048675)3.57842456
30retinal ganglion cell axon guidance (GO:0031290)3.53622605
31nonmotile primary cilium assembly (GO:0035058)3.53325466
32regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.49144911
33hippocampus development (GO:0021766)3.48520101
34kidney morphogenesis (GO:0060993)3.38570918
35response to pheromone (GO:0019236)3.37038405
36establishment of nucleus localization (GO:0040023)3.35864638
37auditory behavior (GO:0031223)3.30023644
38positive regulation of dendritic spine morphogenesis (GO:0061003)3.27111504
39negative regulation of axon extension involved in axon guidance (GO:0048843)3.26660411
40regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)3.25656431
41establishment of mitochondrion localization (GO:0051654)3.24032210
42gamma-aminobutyric acid transport (GO:0015812)3.23674095
43synapse assembly (GO:0007416)3.22738674
44negative regulation of microtubule polymerization (GO:0031115)3.21228206
45presynaptic membrane organization (GO:0097090)3.20490108
46positive regulation of synapse maturation (GO:0090129)3.19787656
47epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.19001648
48regulation of neuron migration (GO:2001222)3.18467956
49mechanosensory behavior (GO:0007638)3.14131645
50negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.12762094
51negative regulation of translation, ncRNA-mediated (GO:0040033)3.12762094
52regulation of translation, ncRNA-mediated (GO:0045974)3.12762094
53neuronal stem cell maintenance (GO:0097150)3.12704160
54postsynaptic membrane organization (GO:0001941)3.12429523
55neuronal ion channel clustering (GO:0045161)3.10972498
56behavioral response to ethanol (GO:0048149)3.10154705
57cellular response to prostaglandin stimulus (GO:0071379)3.09300066
58G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.09106126
59gastrulation with mouth forming second (GO:0001702)3.08672710
60negative regulation of axon guidance (GO:1902668)3.06720408
61protein localization to synapse (GO:0035418)3.06059250
62olfactory bulb development (GO:0021772)3.05559405
63regulation of non-canonical Wnt signaling pathway (GO:2000050)3.04299608
64regulation of axon extension involved in axon guidance (GO:0048841)3.03916595
65astrocyte differentiation (GO:0048708)3.03840246
66cerebellar Purkinje cell layer development (GO:0021680)3.03048795
67cerebral cortex cell migration (GO:0021795)3.03025164
68neuron projection extension (GO:1990138)3.02301733
69neural tube formation (GO:0001841)3.01110249
70positive regulation of axon extension (GO:0045773)2.99005249
71synaptic transmission, cholinergic (GO:0007271)2.96935176
72cerebellar granule cell differentiation (GO:0021707)2.96828959
73regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.95045300
74cranial nerve morphogenesis (GO:0021602)2.94489237
75regulation of axon guidance (GO:1902667)2.93689983
76ionotropic glutamate receptor signaling pathway (GO:0035235)2.93509048
77regulation of glutamate receptor signaling pathway (GO:1900449)2.93362929
78lens morphogenesis in camera-type eye (GO:0002089)2.93081520
79cell proliferation in forebrain (GO:0021846)2.92600944
80spinal cord association neuron differentiation (GO:0021527)2.92417520
81semaphorin-plexin signaling pathway (GO:0071526)2.92181553
82dorsal/ventral axis specification (GO:0009950)2.91918443
83axonogenesis (GO:0007409)2.89238333
84positive regulation of synapse assembly (GO:0051965)2.88144862
85neurotransmitter-gated ion channel clustering (GO:0072578)2.86655548
86neuron fate determination (GO:0048664)2.85010429
87sequestering of actin monomers (GO:0042989)2.83129627
88glutamate receptor signaling pathway (GO:0007215)2.80688934
89mesenchymal-epithelial cell signaling (GO:0060638)2.80277038
90locomotory exploration behavior (GO:0035641)2.80246704
91regulation of telomere maintenance (GO:0032204)2.80054294
92* regulation of axon extension (GO:0030516)2.78990329
93negative regulation of transcription regulatory region DNA binding (GO:2000678)2.78733804
94epithelial cilium movement (GO:0003351)2.77368753
95synaptic transmission, glutamatergic (GO:0035249)2.77206109
96cochlea morphogenesis (GO:0090103)2.75970634
97neuron projection morphogenesis (GO:0048812)2.75757351
98regulation of gene silencing by RNA (GO:0060966)2.75345323
99regulation of posttranscriptional gene silencing (GO:0060147)2.75345323
100regulation of gene silencing by miRNA (GO:0060964)2.75345323
101midbrain development (GO:0030901)2.73834719
102protein polyglutamylation (GO:0018095)2.71795440
103* regulation of extent of cell growth (GO:0061387)2.70256292
104negative regulation of oligodendrocyte differentiation (GO:0048715)2.69088884
105somite development (GO:0061053)2.68939449
106mRNA splice site selection (GO:0006376)2.68644504
107Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.67288029
108central nervous system neuron development (GO:0021954)2.66570795
109* negative regulation of axon extension (GO:0030517)2.66068481
110convergent extension (GO:0060026)2.65919201
111regulation of collateral sprouting (GO:0048670)2.65246278
112negative regulation of telomere maintenance (GO:0032205)2.65000102
113neuromuscular synaptic transmission (GO:0007274)2.62806949
114cellular response to cholesterol (GO:0071397)2.62766648
115prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060522.62731207
116negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.62210452
117regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.61367261
118lung-associated mesenchyme development (GO:0060484)2.60605629
119generation of neurons (GO:0048699)2.59409284
120regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.58983048
121negative regulation of cytosolic calcium ion concentration (GO:0051481)2.58585321
122protein localization to cilium (GO:0061512)2.57971370
123regulation of smoothened signaling pathway (GO:0008589)2.57743297
124startle response (GO:0001964)2.57542794
125forebrain neuron differentiation (GO:0021879)2.57332871
126positive regulation of dendrite morphogenesis (GO:0050775)2.56406371
127short-term memory (GO:0007614)2.55291558
128dopaminergic neuron differentiation (GO:0071542)2.55238355
129vocalization behavior (GO:0071625)2.54413289
130regulation of establishment of planar polarity (GO:0090175)2.53906619
131calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.53687671
132telencephalon cell migration (GO:0022029)2.53198544
133intraciliary transport (GO:0042073)2.52835081
134positive regulation of axonogenesis (GO:0050772)2.52492902
135clathrin coat assembly (GO:0048268)2.51431886
136forebrain neuron development (GO:0021884)2.51100001
137regulation of development, heterochronic (GO:0040034)2.50747520
138* negative regulation of axonogenesis (GO:0050771)2.50683160
139substrate-independent telencephalic tangential migration (GO:0021826)2.50611778
140substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.50611778
141ganglion development (GO:0061548)2.50299323
142limb development (GO:0060173)2.50098036
143appendage development (GO:0048736)2.50098036
144establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.49413344
145mitochondrion transport along microtubule (GO:0047497)2.49413344
146neuronal action potential (GO:0019228)2.49340104
147regulation of synapse assembly (GO:0051963)2.49155365
148regulation of cilium movement (GO:0003352)2.48645549
149negative regulation of smoothened signaling pathway (GO:0045879)2.47899132
150adult walking behavior (GO:0007628)2.45371285
151synapse organization (GO:0050808)2.44288009
152detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.43542794
153negative regulation of synaptic transmission, GABAergic (GO:0032229)2.41993778
154regulation of synapse structural plasticity (GO:0051823)2.41586256
155negative regulation of glial cell differentiation (GO:0045686)2.41105826
156negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.40505828
157fucose catabolic process (GO:0019317)2.39648411
158L-fucose metabolic process (GO:0042354)2.39648411
159L-fucose catabolic process (GO:0042355)2.39648411
160neuronal action potential propagation (GO:0019227)2.39552305
161neuron-neuron synaptic transmission (GO:0007270)2.38884249
162regulation of neurotransmitter uptake (GO:0051580)2.37518673
163thalamus development (GO:0021794)2.37016249
164cilium organization (GO:0044782)2.35136513
165membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.34798878

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.95915932
2GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.40592773
3EZH2_27304074_Chip-Seq_ESCs_Mouse3.02919953
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.91407343
5RBPJ_22232070_ChIP-Seq_NCS_Mouse2.83976684
6EED_16625203_ChIP-ChIP_MESCs_Mouse2.82681111
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.72780650
8NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.71265343
9SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.68292327
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.62883757
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.62883757
12VDR_22108803_ChIP-Seq_LS180_Human2.50754997
13SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.48874495
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.46652638
15RNF2_27304074_Chip-Seq_ESCs_Mouse2.40745599
16PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.39375095
17RNF2_16625203_ChIP-ChIP_MESCs_Mouse2.35812504
18EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.34848569
19SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.33183266
20ZFP57_27257070_Chip-Seq_ESCs_Mouse2.30563047
21CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.27476492
22CBX2_27304074_Chip-Seq_ESCs_Mouse2.27172121
23EZH2_27294783_Chip-Seq_ESCs_Mouse2.24468872
24SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.23627540
25TP63_19390658_ChIP-ChIP_HaCaT_Human2.21397500
26SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.17882260
27GBX2_23144817_ChIP-Seq_PC3_Human2.17481051
28SUZ12_27294783_Chip-Seq_ESCs_Mouse2.10487756
29ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.09849205
30RING1B_27294783_Chip-Seq_NPCs_Mouse2.01806508
31TAF15_26573619_Chip-Seq_HEK293_Human2.01298704
32EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.94154098
33RING1B_27294783_Chip-Seq_ESCs_Mouse1.90401429
34POU5F1_16153702_ChIP-ChIP_HESCs_Human1.88885335
35REST_21632747_ChIP-Seq_MESCs_Mouse1.85276551
36GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.85218103
37MTF2_20144788_ChIP-Seq_MESCs_Mouse1.83538943
38POU3F2_20337985_ChIP-ChIP_501MEL_Human1.81776225
39P300_19829295_ChIP-Seq_ESCs_Human1.80509268
40EWS_26573619_Chip-Seq_HEK293_Human1.79490238
41ZFP281_18757296_ChIP-ChIP_E14_Mouse1.77036339
42TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.75050879
43WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.74527176
44SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.71148997
45TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.62672232
46POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.62672232
47DROSHA_22980978_ChIP-Seq_HELA_Human1.62020921
48OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.61509466
49PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.61236265
50HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.59134946
51ZFP281_27345836_Chip-Seq_ESCs_Mouse1.58965761
52AR_21572438_ChIP-Seq_LNCaP_Human1.58058051
53TP53_20018659_ChIP-ChIP_R1E_Mouse1.57382663
54SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.57160614
55TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.56446504
56MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.55949499
57HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.53309834
58ERG_21242973_ChIP-ChIP_JURKAT_Human1.50807994
59BMI1_23680149_ChIP-Seq_NPCS_Mouse1.49292823
60IRF1_19129219_ChIP-ChIP_H3396_Human1.47245898
61MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.44362435
62RNF2_27304074_Chip-Seq_NSC_Mouse1.41509517
63KDM2B_26808549_Chip-Seq_K562_Human1.41353347
64FLI1_27457419_Chip-Seq_LIVER_Mouse1.39960219
65SALL1_21062744_ChIP-ChIP_HESCs_Human1.38902275
66CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.37914317
67SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.37024222
68CTBP2_25329375_ChIP-Seq_LNCAP_Human1.33636997
69REST_18959480_ChIP-ChIP_MESCs_Mouse1.32793509
70MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.32026933
71STAT6_21828071_ChIP-Seq_BEAS2B_Human1.31289136
72ISL1_27105846_Chip-Seq_CPCs_Mouse1.29833198
73ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.28353815
74SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.25621063
75DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.25263202
76PIAS1_25552417_ChIP-Seq_VCAP_Human1.24349721
77ZNF274_21170338_ChIP-Seq_K562_Hela1.23897876
78UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.23807966
79YAP1_20516196_ChIP-Seq_MESCs_Mouse1.22437120
80ER_23166858_ChIP-Seq_MCF-7_Human1.22342768
81IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.22167123
82CBP_20019798_ChIP-Seq_JUKART_Human1.22167123
83AR_25329375_ChIP-Seq_VCAP_Human1.22048342
84IKZF1_21737484_ChIP-ChIP_HCT116_Human1.21991061
85GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.21398523
86PCGF2_27294783_Chip-Seq_NPCs_Mouse1.20175747
87STAT3_23295773_ChIP-Seq_U87_Human1.19573975
88KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.18711679
89PCGF2_27294783_Chip-Seq_ESCs_Mouse1.16732654
90SOX2_16153702_ChIP-ChIP_HESCs_Human1.16388306
91WT1_19549856_ChIP-ChIP_CCG9911_Human1.15281029
92WT1_25993318_ChIP-Seq_PODOCYTE_Human1.15255756
93RARB_27405468_Chip-Seq_BRAIN_Mouse1.14003353
94AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.13613571
95MYC_18940864_ChIP-ChIP_HL60_Human1.13445610
96BCAT_22108803_ChIP-Seq_LS180_Human1.11939994
97SOX2_21211035_ChIP-Seq_LN229_Gbm1.11718595
98CTBP1_25329375_ChIP-Seq_LNCAP_Human1.11613335
99TCF4_23295773_ChIP-Seq_U87_Human1.10403967
100OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.09075966
101SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.08936471
102FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.08354556
103RUNX2_22187159_ChIP-Seq_PCA_Human1.08119814
104TP53_22573176_ChIP-Seq_HFKS_Human1.07953585
105EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.05357419
106SMAD3_21741376_ChIP-Seq_EPCs_Human1.04948101
107AR_19668381_ChIP-Seq_PC3_Human1.04907488
108TBX3_20139965_ChIP-Seq_ESCs_Mouse1.04764153
109TBX3_20139965_ChIP-Seq_MESCs_Mouse1.03736238
110CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03607008
111E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.03394192
112KLF5_20875108_ChIP-Seq_MESCs_Mouse1.03207059
113FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.03140833
114SOX2_18555785_ChIP-Seq_MESCs_Mouse1.02371705
115SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.01717915
116KDM2B_26808549_Chip-Seq_JURKAT_Human1.01657473
117IGF1R_20145208_ChIP-Seq_DFB_Human1.01049699
118TOP2B_26459242_ChIP-Seq_MCF-7_Human1.00195679
119STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.99711005
120SMAD3_21741376_ChIP-Seq_ESCs_Human0.98034188
121ZNF217_24962896_ChIP-Seq_MCF-7_Human0.97483553
122GATA1_26923725_Chip-Seq_HPCs_Mouse0.97415919
123TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.97278051
124RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.97093236
125FUS_26573619_Chip-Seq_HEK293_Human0.96573457
126POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.96163837
127TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.96025061
128POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.95617956
129RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.94701114
130AHR_22903824_ChIP-Seq_MCF-7_Human0.94684340
131SMAD4_21741376_ChIP-Seq_HESCs_Human0.94497247
132ETV2_25802403_ChIP-Seq_MESCs_Mouse0.94328399
133ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.94221872
134TCF4_22108803_ChIP-Seq_LS180_Human0.93360400
135ARNT_22903824_ChIP-Seq_MCF-7_Human0.91854718
136SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.91641139
137MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91334979
138TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.89521247
139SMAD4_21799915_ChIP-Seq_A2780_Human0.89390051
140TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88148839
141NR3C1_21868756_ChIP-Seq_MCF10A_Human0.87980906

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000778_abnormal_nervous_system3.92104830
2MP0000569_abnormal_digit_pigmentation3.87859633
3MP0000537_abnormal_urethra_morphology3.26315505
4MP0005187_abnormal_penis_morphology3.20307014
5MP0005423_abnormal_somatic_nervous2.82294044
6MP0002938_white_spotting2.49180267
7MP0003136_yellow_coat_color2.38823970
8MP0004859_abnormal_synaptic_plasticity2.38114004
9MP0001529_abnormal_vocalization2.21507574
10MP0006276_abnormal_autonomic_nervous2.16467827
11MP0001299_abnormal_eye_distance/2.13226507
12MP0003938_abnormal_ear_development2.09869241
13MP0006292_abnormal_olfactory_placode2.06647008
14MP0003787_abnormal_imprinting2.05633760
15MP0000566_synostosis2.02159203
16MP0008877_abnormal_DNA_methylation2.01194715
17MP0002822_catalepsy2.01185307
18MP0002736_abnormal_nociception_after2.00350165
19MP0004885_abnormal_endolymph1.99030472
20MP0003861_abnormal_nervous_system1.97357388
21MP0002184_abnormal_innervation1.97144121
22MP0004858_abnormal_nervous_system1.92111271
23MP0004270_analgesia1.88849952
24MP0004133_heterotaxia1.86963969
25MP0008789_abnormal_olfactory_epithelium1.84693063
26MP0000631_abnormal_neuroendocrine_gland1.80794496
27MP0003880_abnormal_central_pattern1.75920572
28MP0002272_abnormal_nervous_system1.74614082
29MP0003385_abnormal_body_wall1.73125559
30MP0000955_abnormal_spinal_cord1.72978269
31MP0000049_abnormal_middle_ear1.72653269
32MP0004142_abnormal_muscle_tone1.70031947
33MP0005257_abnormal_intraocular_pressure1.68235208
34MP0001188_hyperpigmentation1.67128898
35MP0003635_abnormal_synaptic_transmissio1.66223056
36MP0000428_abnormal_craniofacial_morphol1.63709490
37MP0002102_abnormal_ear_morphology1.63602752
38MP0005394_taste/olfaction_phenotype1.63543784
39MP0005499_abnormal_olfactory_system1.63543784
40MP0005248_abnormal_Harderian_gland1.61396186
41MP0002653_abnormal_ependyma_morphology1.59687993
42MP0004811_abnormal_neuron_physiology1.56821019
43MP0002063_abnormal_learning/memory/cond1.56554264
44MP0001293_anophthalmia1.55880505
45MP0005551_abnormal_eye_electrophysiolog1.55544314
46MP0009046_muscle_twitch1.55348541
47MP0002152_abnormal_brain_morphology1.55247925
48MP0002116_abnormal_craniofacial_bone1.54900039
49MP0003755_abnormal_palate_morphology1.53458739
50MP0009250_abnormal_appendicular_skeleto1.51085875
51MP0002282_abnormal_trachea_morphology1.50282072
52MP0001984_abnormal_olfaction1.48604834
53MP0006072_abnormal_retinal_apoptosis1.47843762
54MP0003942_abnormal_urinary_system1.47425417
55MP0003890_abnormal_embryonic-extraembry1.46997519
56MP0010030_abnormal_orbit_morphology1.46620925
57MP0003937_abnormal_limbs/digits/tail_de1.45056406
58MP0002557_abnormal_social/conspecific_i1.45015606
59MP0001485_abnormal_pinna_reflex1.44180137
60MP0003119_abnormal_digestive_system1.43057660
61MP0002882_abnormal_neuron_morphology1.36169685
62MP0003935_abnormal_craniofacial_develop1.35983662
63MP0005076_abnormal_cell_differentiation1.35387829
64MP0005253_abnormal_eye_physiology1.35071965
65MP0002734_abnormal_mechanical_nocicepti1.34172319
66MP0001970_abnormal_pain_threshold1.32280194
67MP0009053_abnormal_anal_canal1.27555443
68MP0002233_abnormal_nose_morphology1.26647700
69MP0001486_abnormal_startle_reflex1.26525538
70MP0003121_genomic_imprinting1.25826505
71MP0002697_abnormal_eye_size1.25657921
72MP0002249_abnormal_larynx_morphology1.24971497
73MP0002067_abnormal_sensory_capabilities1.24008163
74MP0003115_abnormal_respiratory_system1.21781835
75MP0002092_abnormal_eye_morphology1.20326119
76MP0003283_abnormal_digestive_organ1.19970794
77MP0005646_abnormal_pituitary_gland1.18376936
78MP0002081_perinatal_lethality1.18074591
79MP0002751_abnormal_autonomic_nervous1.16320770
80MP0004134_abnormal_chest_morphology1.15156362
81MP0002177_abnormal_outer_ear1.15085958
82MP0005195_abnormal_posterior_eye1.14424740
83MP0002572_abnormal_emotion/affect_behav1.14374979
84MP0000647_abnormal_sebaceous_gland1.13579855
85MP0002234_abnormal_pharynx_morphology1.12357673
86MP0003315_abnormal_perineum_morphology1.12345626
87MP0001286_abnormal_eye_development1.11878971
88MP0000534_abnormal_ureter_morphology1.11823953
89MP0000026_abnormal_inner_ear1.08606733
90MP0009780_abnormal_chondrocyte_physiolo1.08603915
91MP0002932_abnormal_joint_morphology1.07464007
92MP0003011_delayed_dark_adaptation1.07413550
93MP0002909_abnormal_adrenal_gland1.04940337
94MP0002733_abnormal_thermal_nociception1.04197879
95MP0000432_abnormal_head_morphology0.99924892
96MP0000462_abnormal_digestive_system0.99256399
97MP0005377_hearing/vestibular/ear_phenot0.98819835
98MP0003878_abnormal_ear_physiology0.98819835
99MP0003567_abnormal_fetal_cardiomyocyte0.95413763
100MP0002735_abnormal_chemical_nociception0.94671709
101MP0001177_atelectasis0.94450139
102MP0002752_abnormal_somatic_nervous0.93289538
103MP0001502_abnormal_circadian_rhythm0.92742574
104MP0009745_abnormal_behavioral_response0.92330274
105MP0005386_behavior/neurological_phenoty0.92077529
106MP0004924_abnormal_behavior0.92077529
107MP0001963_abnormal_hearing_physiology0.90843275
108MP0001986_abnormal_taste_sensitivity0.90808088
109MP0003122_maternal_imprinting0.90130421
110MP0001905_abnormal_dopamine_level0.89383511
111MP0004742_abnormal_vestibular_system0.88967698
112MP0002114_abnormal_axial_skeleton0.86984362
113MP0001346_abnormal_lacrimal_gland0.86823897
114MP0001501_abnormal_sleep_pattern0.85095736
115MP0001968_abnormal_touch/_nociception0.84688768
116MP0008995_early_reproductive_senescence0.84087911
117MP0009379_abnormal_foot_pigmentation0.83653521
118MP0004043_abnormal_pH_regulation0.83409837
119MP0001440_abnormal_grooming_behavior0.83017564
120MP0002064_seizures0.80513636
121MP0005391_vision/eye_phenotype0.79995217
122MP0002069_abnormal_eating/drinking_beha0.79704636
123MP0001849_ear_inflammation0.79503709
124MP0002638_abnormal_pupillary_reflex0.79025592
125MP0008872_abnormal_physiological_respon0.78997626
126MP0005409_darkened_coat_color0.78368196
127MP0003195_calcinosis0.78198624
128MP0002084_abnormal_developmental_patter0.78134824
129MP0001324_abnormal_eye_pigmentation0.77743687
130MP0001340_abnormal_eyelid_morphology0.77730966
131MP0005084_abnormal_gallbladder_morpholo0.77461347
132MP0004145_abnormal_muscle_electrophysio0.77169069
133MP0005503_abnormal_tendon_morphology0.77052451
134MP0002066_abnormal_motor_capabilities/c0.76311618
135MP0002085_abnormal_embryonic_tissue0.75880838
136MP0000733_abnormal_muscle_development0.72559405
137MP0005645_abnormal_hypothalamus_physiol0.71608251

Predicted human phenotypes

RankGene SetZ-score
1Short 4th metacarpal (HP:0010044)5.33364671
2Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)5.33364671
3Abnormality of the 4th metacarpal (HP:0010012)4.17942968
4Trigonocephaly (HP:0000243)3.73744474
5Shallow orbits (HP:0000586)3.67247090
6Abnormality of the parietal bone (HP:0002696)3.51922501
7Pancreatic cysts (HP:0001737)3.50070600
8Abnormality of the diencephalon (HP:0010662)3.47458285
9Midline defect of the nose (HP:0004122)3.46014683
10Abnormality of midbrain morphology (HP:0002418)3.39134733
11Molar tooth sign on MRI (HP:0002419)3.39134733
12Type II lissencephaly (HP:0007260)3.38304626
13Overriding aorta (HP:0002623)3.27156843
14Pancreatic fibrosis (HP:0100732)3.26028159
15Nephronophthisis (HP:0000090)3.23772795
16True hermaphroditism (HP:0010459)3.20115341
17Hyperacusis (HP:0010780)3.08893240
18Hyperventilation (HP:0002883)3.06733944
19Cortical dysplasia (HP:0002539)3.05943860
20Renal duplication (HP:0000075)3.01255627
21Neoplasm of the heart (HP:0100544)2.98204417
22Septo-optic dysplasia (HP:0100842)2.94906594
23Elfin facies (HP:0004428)2.94322217
24Medial flaring of the eyebrow (HP:0010747)2.86486969
25Renovascular hypertension (HP:0100817)2.86067392
26Aqueductal stenosis (HP:0002410)2.77939054
27Hepatoblastoma (HP:0002884)2.77161139
28Abnormality of the renal medulla (HP:0100957)2.76752320
29Retinal dysplasia (HP:0007973)2.76084149
30Gait imbalance (HP:0002141)2.74311707
31Abnormality of the labia minora (HP:0012880)2.74024777
32Megalencephaly (HP:0001355)2.71095688
33Anteriorly placed anus (HP:0001545)2.68993177
34Broad-based gait (HP:0002136)2.62334774
35Optic nerve hypoplasia (HP:0000609)2.59733571
36Cerebellar dysplasia (HP:0007033)2.51609178
37Chronic hepatic failure (HP:0100626)2.50043942
38Focal motor seizures (HP:0011153)2.49278469
39Anophthalmia (HP:0000528)2.47489939
40Excessive salivation (HP:0003781)2.46331576
41Drooling (HP:0002307)2.46331576
42Insomnia (HP:0100785)2.44710801
43Pendular nystagmus (HP:0012043)2.42231373
44Protruding tongue (HP:0010808)2.40166812
45Congenital primary aphakia (HP:0007707)2.39349507
46Limb dystonia (HP:0002451)2.39304763
47Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)2.38172353
48Vaginal atresia (HP:0000148)2.37941486
49Nephrogenic diabetes insipidus (HP:0009806)2.37455749
50Congenital stationary night blindness (HP:0007642)2.37162930
51Anencephaly (HP:0002323)2.36889003
52Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.35823530
53Genital tract atresia (HP:0001827)2.35800843
54Germ cell neoplasia (HP:0100728)2.34273842
55Aplasia/Hypoplasia of the sternum (HP:0006714)2.33200061
56Colon cancer (HP:0003003)2.32562438
57Coronal craniosynostosis (HP:0004440)2.32030091
58Rib fusion (HP:0000902)2.31987215
59Medulloblastoma (HP:0002885)2.31002440
60Intestinal atresia (HP:0011100)2.30999071
61Down-sloping shoulders (HP:0200021)2.26114182
62Sclerocornea (HP:0000647)2.24969296
63Focal seizures (HP:0007359)2.23600021
64Abnormal number of incisors (HP:0011064)2.22859278
65Pachygyria (HP:0001302)2.22806403
66Flat cornea (HP:0007720)2.22481939
67Myokymia (HP:0002411)2.22140070
68Patellar aplasia (HP:0006443)2.21341391
69Short phalanx of the thumb (HP:0009660)2.19762352
70Choanal stenosis (HP:0000452)2.19444726
71Abnormality of the renal cortex (HP:0011035)2.16789358
72Obstructive sleep apnea (HP:0002870)2.16008230
73Inability to walk (HP:0002540)2.15744799
74Cystic liver disease (HP:0006706)2.15635973
75Supernumerary ribs (HP:0005815)2.15549158
76Agitation (HP:0000713)2.11506941
77Omphalocele (HP:0001539)2.11194650
78Progressive cerebellar ataxia (HP:0002073)2.09654924
79Sacral dimple (HP:0000960)2.07834001
80Aplasia/Hypoplasia of the patella (HP:0006498)2.07072978
81Inappropriate behavior (HP:0000719)2.04789498
82Glioma (HP:0009733)2.03199559
83Exostoses (HP:0100777)2.03095862
84Tubular atrophy (HP:0000092)2.02729290
85Large earlobe (HP:0009748)2.02447721
86Intellectual disability, moderate (HP:0002342)2.02447376
87Alacrima (HP:0000522)2.02042278
88Hyperglycinemia (HP:0002154)2.01631740
89Facial hemangioma (HP:0000329)2.00611932
90Spina bifida occulta (HP:0003298)2.00282259
91Postaxial hand polydactyly (HP:0001162)1.98668199
92Amyotrophic lateral sclerosis (HP:0007354)1.98443487
93Heterotopia (HP:0002282)1.97231914
94Abnormality of the corticospinal tract (HP:0002492)1.96939683
95Oligodactyly (HP:0012165)1.96470960
96Neoplasm of the oral cavity (HP:0100649)1.95824174
97Absent speech (HP:0001344)1.95265993
98Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.93571770
99Narrow forehead (HP:0000341)1.92964512
100Insidious onset (HP:0003587)1.92742744
101Termporal pattern (HP:0011008)1.92742744
102Bilateral microphthalmos (HP:0007633)1.92465700
103Polymicrogyria (HP:0002126)1.92434355
104Hypoplasia of the brainstem (HP:0002365)1.91326032
105Aplasia/Hypoplasia of the brainstem (HP:0007362)1.91326032
106Specific learning disability (HP:0001328)1.91099290
107Oligodactyly (hands) (HP:0001180)1.90471009
108Poor coordination (HP:0002370)1.90352241
109Dandy-Walker malformation (HP:0001305)1.90008714
110Leiomyosarcoma (HP:0100243)1.89910070
111Uterine leiomyosarcoma (HP:0002891)1.89910070
112Lissencephaly (HP:0001339)1.88772429
113Abnormality of the antihelix (HP:0009738)1.87819103
114Increased nuchal translucency (HP:0010880)1.87422525
115Hamartoma (HP:0010566)1.87419045
116Supernumerary spleens (HP:0009799)1.87237962
117Obsessive-compulsive behavior (HP:0000722)1.85924822
118Overgrowth (HP:0001548)1.85921581
119Micropenis (HP:0000054)1.85678384
120Epileptic encephalopathy (HP:0200134)1.84661776
121Renal hypoplasia (HP:0000089)1.83435335
122Abolished electroretinogram (ERG) (HP:0000550)1.83376807
123Supernumerary bones of the axial skeleton (HP:0009144)1.83157911
124Absent septum pellucidum (HP:0001331)1.82861680
125Abnormality of the nasal septum (HP:0000419)1.82058928
126Abnormality of the distal phalanx of the thumb (HP:0009617)1.81129724
127Growth hormone deficiency (HP:0000824)1.80856794
128Increased number of teeth (HP:0011069)1.79914909
129Preaxial hand polydactyly (HP:0001177)1.79741378
130Hemiparesis (HP:0001269)1.79249835
131Patellar dislocation (HP:0002999)1.79031307
132Vesicoureteral reflux (HP:0000076)1.77932576
133Short philtrum (HP:0000322)1.77648503
134Hemivertebrae (HP:0002937)1.77369197
135Sleep apnea (HP:0010535)1.77272386
136Postaxial foot polydactyly (HP:0001830)1.76235930
137Shoulder girdle muscle weakness (HP:0003547)1.75382774
138Astrocytoma (HP:0009592)1.75088690
139Abnormality of the astrocytes (HP:0100707)1.75088690
140Transitional cell carcinoma of the bladder (HP:0006740)1.74914212
141Aplasia/Hypoplasia of the tongue (HP:0010295)1.74713119
142Febrile seizures (HP:0002373)1.74572639
143Decreased lacrimation (HP:0000633)1.74372685
144Gastrointestinal atresia (HP:0002589)1.74190161
145Aplasia involving bones of the extremities (HP:0009825)1.74095976
146Aplasia involving bones of the upper limbs (HP:0009823)1.74095976
147Aplasia of the phalanges of the hand (HP:0009802)1.74095976
148Megalocornea (HP:0000485)1.73298731
149Macroorchidism (HP:0000053)1.73250989
150Genetic anticipation (HP:0003743)1.73216100
151Congenital hepatic fibrosis (HP:0002612)1.72822107
152Chorioretinal atrophy (HP:0000533)1.72522895
153Turricephaly (HP:0000262)1.72519570
154Deviation of the hallux (HP:0010051)1.71025844
155Esophageal atresia (HP:0002032)1.70324298
156Meningocele (HP:0002435)1.70081716
157Pointed chin (HP:0000307)1.69476786
158Anterior segment dysgenesis (HP:0007700)1.69440421
159Progressive inability to walk (HP:0002505)1.68866731
160Severe muscular hypotonia (HP:0006829)1.68525068
161Heterochromia iridis (HP:0001100)1.67493587
162Occipital encephalocele (HP:0002085)1.66223812
163Disinhibition (HP:0000734)1.66023602
164Abnormality of salivation (HP:0100755)1.65603872
165Narrow palate (HP:0000189)1.65446641
166Optic nerve coloboma (HP:0000588)1.65310899
167Thyroid-stimulating hormone excess (HP:0002925)1.65278085
168Abnormality of the incisor (HP:0000676)1.65257482
169Cutaneous finger syndactyly (HP:0010554)1.64875611
170Ankle clonus (HP:0011448)1.64497191
171Aplasia/Hypoplasia of the tibia (HP:0005772)1.63225495
172Polyphagia (HP:0002591)1.62720824
173Hallux valgus (HP:0001822)1.62336855
174Arnold-Chiari malformation (HP:0002308)1.61624250
175Labial hypoplasia (HP:0000066)1.61542197
176Aplasia/Hypoplasia of the spleen (HP:0010451)1.59365971
177Abnormality of the septum pellucidum (HP:0007375)1.59273678
178Abnormal drinking behavior (HP:0030082)1.57198666
179Polydipsia (HP:0001959)1.57198666
180Broad foot (HP:0001769)1.56548200

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK17.66289184
2DYRK23.17948508
3ERBB32.90663956
4EPHB22.73937303
5SIK22.52669687
6MAPK132.41577894
7FRK2.37682375
8FGFR22.33576339
9NTRK22.16808624
10ADRBK22.02329375
11MAP4K22.01363397
12KSR11.94383246
13TNIK1.78643862
14WNK41.67470347
15CASK1.66281240
16CSNK1A1L1.58969307
17TRIM281.53166811
18PAK61.52177417
19PINK11.49348200
20CSNK1G31.45492051
21CSNK1G21.44118529
22ZAK1.42360559
23PHKG21.42052242
24PHKG11.42052242
25TRIB31.41754224
26PDGFRA1.41005928
27NTRK31.39363925
28SIK11.38756484
29NUAK11.38265688
30INSRR1.37363400
31MKNK11.35567219
32ICK1.35432763
33PRKCG1.31904569
34GRK11.30217367
35MAP3K41.29407594
36TYRO31.26198323
37UHMK11.25306791
38LATS11.20716281
39LIMK11.20176781
40MKNK21.19602805
41MINK11.15393218
42CSNK1G11.13757424
43ERBB21.10801230
44IRAK21.08334967
45DDR21.07319315
46BCR1.05559305
47DAPK21.02062068
48CAMK1G0.98674948
49MAP2K40.97462333
50LATS20.96070064
51EEF2K0.95953163
52MARK20.95029235
53ILK0.94714340
54FGFR10.94498516
55STK390.93169778
56MAP2K70.92801382
57CDK50.84980920
58DYRK30.83794841
59TLK10.83111195
60OXSR10.82345393
61SGK2230.81876188
62SGK4940.81876188
63DYRK1A0.80898571
64RPS6KA20.80059400
65PNCK0.77847410
66NEK20.77535894
67STK38L0.77074474
68TAOK10.74350263
69VRK10.74171542
70PRKCZ0.73795625
71ACVR1B0.73678877
72BMPR1B0.72690813
73PLK20.72190900
74PKN10.71861133
75PTK60.71500563
76SGK20.71276418
77PRKCE0.70562914
78MAP3K100.70208433
79DYRK1B0.70071373
80SRPK10.68223740
81RIPK10.68156378
82STK110.67293206
83LMTK20.67235290
84CDK180.66102079
85ROCK10.65721838
86CDK150.65632710
87ERBB40.65020276
88MAP3K90.64078148
89CDK140.61356052
90MAPK150.60708358
91BCKDK0.60281318
92MAPK90.60276510
93CDK190.60196495
94PRPF4B0.59693149
95ALK0.59359758
96CDK11A0.58939706
97HIPK20.58648220
98STK160.58082748
99ROCK20.57038525
100PAK30.56754900
101SGK30.56241968
102CAMKK20.55141356
103CAMK2A0.54096594
104CDC70.53340939
105RET0.53295317
106TGFBR10.53123597
107EPHA40.52429781
108CDK60.51500473
109PDGFRB0.51412674
110NTRK10.50973522
111YES10.50117848
112PLK40.49940406
113MAPK80.49916847
114IRAK10.49495116
115CSNK1D0.48416375
116PLK30.48038881
117CAMK40.47378988
118PRKD30.46739576
119CHEK20.46724757
120NME10.45587431
121CSNK1E0.44167639
122ADRBK10.43686192
123EPHA30.42944326
124TAF10.42454131
125PRKACA0.42217540
126PASK0.40836472
127CAMK10.40699718
128CDK10.40575544
129CSNK1A10.40427773
130TIE10.40371260
131WNK30.39392060
132MTOR0.39364552
133WEE10.38900532
134PRKCI0.38734481
135PKN20.38731290
136FGR0.38328873
137CDK80.37565495
138GSK3B0.37550796
139BRD40.37543487
140PLK10.36909134
141CAMKK10.36372334
142NLK0.35644314
143CDK30.35627861
144CAMK1D0.34600341
145RPS6KA50.34504493

Predicted pathways (KEGG)

RankGene SetZ-score
1Basal cell carcinoma_Homo sapiens_hsa052173.38751304
2Axon guidance_Homo sapiens_hsa043603.03422059
3Hedgehog signaling pathway_Homo sapiens_hsa043402.85301865
4Phototransduction_Homo sapiens_hsa047442.61252065
5Colorectal cancer_Homo sapiens_hsa052102.49807093
6Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.41232135
7Oxidative phosphorylation_Homo sapiens_hsa001902.38848279
8Endometrial cancer_Homo sapiens_hsa052132.33268620
9Parkinsons disease_Homo sapiens_hsa050122.16110546
10Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.04673273
11Cardiac muscle contraction_Homo sapiens_hsa042601.91976269
12Hippo signaling pathway_Homo sapiens_hsa043901.90198110
13Butanoate metabolism_Homo sapiens_hsa006501.89450700
14alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.88185283
15Wnt signaling pathway_Homo sapiens_hsa043101.86576562
16Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.85668172
17Linoleic acid metabolism_Homo sapiens_hsa005911.82975811
18Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.80909708
19Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.79893192
20RNA polymerase_Homo sapiens_hsa030201.71042297
21Basal transcription factors_Homo sapiens_hsa030221.66146262
22ErbB signaling pathway_Homo sapiens_hsa040121.64502844
23Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.63599989
24Renal cell carcinoma_Homo sapiens_hsa052111.60811182
25Glioma_Homo sapiens_hsa052141.60761185
26Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.58724168
27Notch signaling pathway_Homo sapiens_hsa043301.58088201
28Chronic myeloid leukemia_Homo sapiens_hsa052201.57702374
29MicroRNAs in cancer_Homo sapiens_hsa052061.54795502
30Nicotine addiction_Homo sapiens_hsa050331.53652859
31Huntingtons disease_Homo sapiens_hsa050161.53019468
32Steroid biosynthesis_Homo sapiens_hsa001001.48453280
33Fanconi anemia pathway_Homo sapiens_hsa034601.47630208
34Ether lipid metabolism_Homo sapiens_hsa005651.47433649
35Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.46729341
36Viral myocarditis_Homo sapiens_hsa054161.46399880
37Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.45373066
38Gap junction_Homo sapiens_hsa045401.42412409
39Protein export_Homo sapiens_hsa030601.41730471
40Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.41652624
41Dopaminergic synapse_Homo sapiens_hsa047281.40901901
42Glutamatergic synapse_Homo sapiens_hsa047241.36169623
43Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.34759195
44Alzheimers disease_Homo sapiens_hsa050101.33450066
45Nitrogen metabolism_Homo sapiens_hsa009101.33317071
46Cholinergic synapse_Homo sapiens_hsa047251.32518563
47Selenocompound metabolism_Homo sapiens_hsa004501.32144380
48Circadian entrainment_Homo sapiens_hsa047131.29192662
49Melanoma_Homo sapiens_hsa052181.29017032
50Non-small cell lung cancer_Homo sapiens_hsa052231.28890825
51mRNA surveillance pathway_Homo sapiens_hsa030151.27294842
52Neurotrophin signaling pathway_Homo sapiens_hsa047221.24821457
53Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.20929770
54Cocaine addiction_Homo sapiens_hsa050301.19828604
55Type II diabetes mellitus_Homo sapiens_hsa049301.18452472
56Melanogenesis_Homo sapiens_hsa049161.18120461
57RNA degradation_Homo sapiens_hsa030181.17026386
58Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.16719590
59GABAergic synapse_Homo sapiens_hsa047271.14800493
60Pancreatic cancer_Homo sapiens_hsa052121.12962473
61Pathways in cancer_Homo sapiens_hsa052001.11811725
62Morphine addiction_Homo sapiens_hsa050321.11281163
63Thyroid hormone signaling pathway_Homo sapiens_hsa049191.11061952
64Insulin secretion_Homo sapiens_hsa049111.10850672
65mTOR signaling pathway_Homo sapiens_hsa041501.10041099
66Estrogen signaling pathway_Homo sapiens_hsa049151.10016185
67Ribosome_Homo sapiens_hsa030101.09676459
68Adherens junction_Homo sapiens_hsa045201.09497534
69Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.06950284
70Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.06014955
71Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.05458143
72Maturity onset diabetes of the young_Homo sapiens_hsa049501.05253122
73Olfactory transduction_Homo sapiens_hsa047401.00947402
74Prostate cancer_Homo sapiens_hsa052151.00109131
75Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.99840436
76Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.99702815
77Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.99546082
78Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.99347182
79Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.99120362
80Propanoate metabolism_Homo sapiens_hsa006400.98813441
81Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.97424657
82Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.96730131
83Homologous recombination_Homo sapiens_hsa034400.96300148
84Lysine degradation_Homo sapiens_hsa003100.94365210
85Long-term depression_Homo sapiens_hsa047300.94115578
86TGF-beta signaling pathway_Homo sapiens_hsa043500.93957932
87Proteoglycans in cancer_Homo sapiens_hsa052050.93546669
88MAPK signaling pathway_Homo sapiens_hsa040100.92831220
89Choline metabolism in cancer_Homo sapiens_hsa052310.91057044
90Rap1 signaling pathway_Homo sapiens_hsa040150.90882149
91Tryptophan metabolism_Homo sapiens_hsa003800.90683126
92Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.88986487
93Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.88895186
94Ras signaling pathway_Homo sapiens_hsa040140.88272261
95Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.87363240
96Serotonergic synapse_Homo sapiens_hsa047260.86926931
97Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.85247095
98Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.85242680
99Renin secretion_Homo sapiens_hsa049240.85022766
100Tight junction_Homo sapiens_hsa045300.84198788
101Alcoholism_Homo sapiens_hsa050340.83816246
102Prolactin signaling pathway_Homo sapiens_hsa049170.83585588
103Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.82880566
104Caffeine metabolism_Homo sapiens_hsa002320.81748785
105Oxytocin signaling pathway_Homo sapiens_hsa049210.81215618
106Synaptic vesicle cycle_Homo sapiens_hsa047210.79843183
107Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.79653538
108Collecting duct acid secretion_Homo sapiens_hsa049660.78437241
109AMPK signaling pathway_Homo sapiens_hsa041520.78157883
110Spliceosome_Homo sapiens_hsa030400.77170038
111VEGF signaling pathway_Homo sapiens_hsa043700.76966122
112cAMP signaling pathway_Homo sapiens_hsa040240.76418139
113FoxO signaling pathway_Homo sapiens_hsa040680.76149583
114Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.75784348
115Regulation of actin cytoskeleton_Homo sapiens_hsa048100.75742655
116Long-term potentiation_Homo sapiens_hsa047200.74786699
117Focal adhesion_Homo sapiens_hsa045100.74653641
118Small cell lung cancer_Homo sapiens_hsa052220.73270168
119Peroxisome_Homo sapiens_hsa041460.72624933
120Dorso-ventral axis formation_Homo sapiens_hsa043200.71491137
121Sphingolipid signaling pathway_Homo sapiens_hsa040710.70841164
122Phospholipase D signaling pathway_Homo sapiens_hsa040720.70839031
123Transcriptional misregulation in cancer_Homo sapiens_hsa052020.70401679
124Longevity regulating pathway - mammal_Homo sapiens_hsa042110.69888448
125Regulation of autophagy_Homo sapiens_hsa041400.69095355
126Amphetamine addiction_Homo sapiens_hsa050310.68951846
127Central carbon metabolism in cancer_Homo sapiens_hsa052300.68538329
128Insulin signaling pathway_Homo sapiens_hsa049100.66717466
129Taste transduction_Homo sapiens_hsa047420.65463711
130AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.65066397
131Oocyte meiosis_Homo sapiens_hsa041140.64527272
132Calcium signaling pathway_Homo sapiens_hsa040200.64054650
133GnRH signaling pathway_Homo sapiens_hsa049120.63703826
134Aldosterone synthesis and secretion_Homo sapiens_hsa049250.63017860
135Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.61892133
136Salivary secretion_Homo sapiens_hsa049700.60244735
137Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.59752430
138PI3K-Akt signaling pathway_Homo sapiens_hsa041510.59732938
139Ovarian steroidogenesis_Homo sapiens_hsa049130.57884844
140Bladder cancer_Homo sapiens_hsa052190.57207287
141Retinol metabolism_Homo sapiens_hsa008300.56608764
142HTLV-I infection_Homo sapiens_hsa051660.55899939
143Endocytosis_Homo sapiens_hsa041440.55373012
144Primary bile acid biosynthesis_Homo sapiens_hsa001200.54475409
145Dilated cardiomyopathy_Homo sapiens_hsa054140.53145245
146Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.52386368
147Steroid hormone biosynthesis_Homo sapiens_hsa001400.52361521
148beta-Alanine metabolism_Homo sapiens_hsa004100.47995408
149Purine metabolism_Homo sapiens_hsa002300.45149049
150Metabolic pathways_Homo sapiens_hsa011000.42018331
151Fat digestion and absorption_Homo sapiens_hsa049750.41145780
152Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.41015103
153Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.38418525
154RNA transport_Homo sapiens_hsa030130.38213306
155Glycerolipid metabolism_Homo sapiens_hsa005610.37942647
156Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.37623481
157Gastric acid secretion_Homo sapiens_hsa049710.34410319
158Chemical carcinogenesis_Homo sapiens_hsa052040.32685855
159Arachidonic acid metabolism_Homo sapiens_hsa005900.30506666

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