DPF1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1postsynaptic membrane organization (GO:0001941)6.02817834
2presynaptic membrane assembly (GO:0097105)5.71499133
3positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.47009287
4neuron cell-cell adhesion (GO:0007158)5.45235557
5presynaptic membrane organization (GO:0097090)5.08484941
6regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.06385978
7protein localization to synapse (GO:0035418)4.97983002
8vocalization behavior (GO:0071625)4.87257383
9nucleobase catabolic process (GO:0046113)4.77954577
10neuronal action potential propagation (GO:0019227)4.66190278
11ionotropic glutamate receptor signaling pathway (GO:0035235)4.59349648
12positive regulation of dendritic spine development (GO:0060999)4.51635718
13gamma-aminobutyric acid transport (GO:0015812)4.45203500
14positive regulation of dendritic spine morphogenesis (GO:0061003)4.33456387
15establishment of mitochondrion localization (GO:0051654)4.29241449
16synaptic vesicle docking involved in exocytosis (GO:0016081)4.27994338
17regulation of glutamate receptor signaling pathway (GO:1900449)4.16307075
18positive regulation of synapse assembly (GO:0051965)4.13005116
19behavioral response to nicotine (GO:0035095)4.09005823
20dendritic spine morphogenesis (GO:0060997)4.07446486
21glutamate receptor signaling pathway (GO:0007215)4.01117365
22neurotransmitter secretion (GO:0007269)4.00078418
23positive regulation of membrane potential (GO:0045838)3.99864072
24neurotransmitter-gated ion channel clustering (GO:0072578)3.88833351
25central nervous system projection neuron axonogenesis (GO:0021952)3.85091042
26facial nerve structural organization (GO:0021612)3.84744491
27positive regulation of synaptic transmission, GABAergic (GO:0032230)3.80153992
28synaptic transmission, glutamatergic (GO:0035249)3.75417059
29auditory behavior (GO:0031223)3.69476875
30regulation of short-term neuronal synaptic plasticity (GO:0048172)3.61714272
31cranial nerve morphogenesis (GO:0021602)3.60574756
32regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.58933772
33neuron recognition (GO:0008038)3.58000776
34righting reflex (GO:0060013)3.57386185
35mitochondrion transport along microtubule (GO:0047497)3.56363625
36establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.56363625
37regulation of excitatory postsynaptic membrane potential (GO:0060079)3.52643067
38short-term memory (GO:0007614)3.50339906
39transmission of nerve impulse (GO:0019226)3.48938188
40regulation of synapse assembly (GO:0051963)3.48502684
41neuron-neuron synaptic transmission (GO:0007270)3.45235048
42central nervous system neuron axonogenesis (GO:0021955)3.43142269
43regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.41376974
44regulation of pigment cell differentiation (GO:0050932)3.39918680
45positive regulation of neurotransmitter secretion (GO:0001956)3.39128443
46mechanosensory behavior (GO:0007638)3.38642487
47cerebral cortex radially oriented cell migration (GO:0021799)3.37038816
48regulation of postsynaptic membrane potential (GO:0060078)3.31587676
49regulation of respiratory system process (GO:0044065)3.31354365
50cranial nerve structural organization (GO:0021604)3.30102901
51regulation of dendritic spine development (GO:0060998)3.29988007
52synaptic vesicle exocytosis (GO:0016079)3.29253389
53negative regulation of synaptic transmission, GABAergic (GO:0032229)3.28206343
54positive regulation of synapse maturation (GO:0090129)3.24244666
55axon ensheathment in central nervous system (GO:0032291)3.24176963
56central nervous system myelination (GO:0022010)3.24176963
57neuromuscular synaptic transmission (GO:0007274)3.21525767
58regulation of dendritic spine morphogenesis (GO:0061001)3.21074804
59neurotransmitter transport (GO:0006836)3.18562231
60negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.15948936
61regulation of respiratory gaseous exchange (GO:0043576)3.12033680
62regulation of vesicle fusion (GO:0031338)3.11822653
63generation of neurons (GO:0048699)3.11367309
64regulation of neurotransmitter levels (GO:0001505)3.11240004
65regulation of synaptic vesicle exocytosis (GO:2000300)3.08015889
66pyrimidine nucleobase catabolic process (GO:0006208)3.04279100
67regulation of long-term neuronal synaptic plasticity (GO:0048169)3.03818939
68positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.03778991
69G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.02839690
70gamma-aminobutyric acid signaling pathway (GO:0007214)3.02087800
71regulation of neuronal synaptic plasticity (GO:0048168)3.01293254
72regulation of neurotransmitter secretion (GO:0046928)3.00904720
73startle response (GO:0001964)2.98756546
74exploration behavior (GO:0035640)2.97433672
75synapse assembly (GO:0007416)2.97239158
76membrane depolarization during action potential (GO:0086010)2.97160962
77regulation of synapse organization (GO:0050807)2.97107482
78positive regulation of neurotransmitter transport (GO:0051590)2.91402172
79positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.91013555
80regulation of synapse maturation (GO:0090128)2.90487977
81regulation of synaptic transmission, GABAergic (GO:0032228)2.90391157
82response to auditory stimulus (GO:0010996)2.87250749
83cell migration in hindbrain (GO:0021535)2.87247178
84dendrite development (GO:0016358)2.86993491
85adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.86455713
86dendritic spine organization (GO:0097061)2.86382300
87long-term memory (GO:0007616)2.85965282
88axon cargo transport (GO:0008088)2.85562604
89axonal fasciculation (GO:0007413)2.85356242
90regulation of neurotransmitter transport (GO:0051588)2.84621914
91calcium ion-dependent exocytosis (GO:0017156)2.84213123
92learning (GO:0007612)2.84202134
93synaptic vesicle maturation (GO:0016188)2.83281459
94sympathetic nervous system development (GO:0048485)2.82231365
95regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.81415365
96positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.79742047
97positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.79674942
98synaptic vesicle endocytosis (GO:0048488)2.79360284
99regulation of synapse structural plasticity (GO:0051823)2.79327387
100lymphoid progenitor cell differentiation (GO:0002320)2.78947952
101layer formation in cerebral cortex (GO:0021819)2.76219221
102behavioral defense response (GO:0002209)2.76149081
103behavioral fear response (GO:0001662)2.76149081
104adult walking behavior (GO:0007628)2.74479391
105neurofilament cytoskeleton organization (GO:0060052)2.73381405
106membrane depolarization (GO:0051899)2.72989849
107regulation of voltage-gated calcium channel activity (GO:1901385)2.72709541
108protein localization to cilium (GO:0061512)2.72540444
109regulation of glutamate secretion (GO:0014048)2.70282914
110synapse organization (GO:0050808)2.70038543
111locomotory exploration behavior (GO:0035641)2.69866805
112anterograde axon cargo transport (GO:0008089)2.69539554
113regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.68719023
114limb bud formation (GO:0060174)2.67498105
115regulation of synaptic vesicle transport (GO:1902803)2.67305896
116response to histamine (GO:0034776)2.66999610
117protein polyglutamylation (GO:0018095)2.66806729
118adult behavior (GO:0030534)2.66660863
119membrane assembly (GO:0071709)2.66502493
120synaptic transmission (GO:0007268)2.65307780
121response to pheromone (GO:0019236)2.64236713
122response to dietary excess (GO:0002021)2.64121909
123social behavior (GO:0035176)2.63290993
124intraspecies interaction between organisms (GO:0051703)2.63290993
125neuronal ion channel clustering (GO:0045161)2.62780932
126regulation of microtubule-based movement (GO:0060632)2.60548281
127regulation of synaptic transmission, glutamatergic (GO:0051966)2.59485574
128membrane hyperpolarization (GO:0060081)2.55611059
129regulation of protein kinase A signaling (GO:0010738)2.55142808
130negative regulation of neurotransmitter transport (GO:0051589)2.55037255
131fear response (GO:0042596)2.54368956
132associative learning (GO:0008306)2.52513398
133membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.51798223
134positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.49483841
135glutamate secretion (GO:0014047)2.45665972
136peptidyl-threonine dephosphorylation (GO:0035970)2.45087425
137dendrite morphogenesis (GO:0048813)2.44480516

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human7.68982524
2GBX2_23144817_ChIP-Seq_PC3_Human3.89022059
3JARID2_20064375_ChIP-Seq_MESCs_Mouse3.62416093
4EZH2_27304074_Chip-Seq_ESCs_Mouse3.19197963
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.04904492
6JARID2_20075857_ChIP-Seq_MESCs_Mouse2.87387275
7SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.79013244
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.76553017
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.76553017
10SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.68858534
11EED_16625203_ChIP-ChIP_MESCs_Mouse2.65194376
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.55440738
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.52607644
14EZH2_27294783_Chip-Seq_ESCs_Mouse2.43843542
15SUZ12_27294783_Chip-Seq_ESCs_Mouse2.43244650
16CBX2_27304074_Chip-Seq_ESCs_Mouse2.33744041
17BMI1_23680149_ChIP-Seq_NPCS_Mouse2.30143703
18RNF2_27304074_Chip-Seq_ESCs_Mouse2.26556528
19REST_21632747_ChIP-Seq_MESCs_Mouse2.24597679
20SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.21436670
21PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.17046446
22ZFP57_27257070_Chip-Seq_ESCs_Mouse2.16456695
23MTF2_20144788_ChIP-Seq_MESCs_Mouse2.16011195
24TAF15_26573619_Chip-Seq_HEK293_Human2.14074026
25TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.08288112
26CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.06192439
27NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.98436552
28RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.98327530
29GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.95712470
30RNF2_27304074_Chip-Seq_NSC_Mouse1.92967942
31IGF1R_20145208_ChIP-Seq_DFB_Human1.91705455
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.82059848
33RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.81569796
34IKZF1_21737484_ChIP-ChIP_HCT116_Human1.79561595
35CTBP2_25329375_ChIP-Seq_LNCAP_Human1.78358899
36HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.68738124
37REST_18959480_ChIP-ChIP_MESCs_Mouse1.64841412
38AR_21572438_ChIP-Seq_LNCaP_Human1.56240556
39P300_19829295_ChIP-Seq_ESCs_Human1.52296075
40PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.50021853
41DROSHA_22980978_ChIP-Seq_HELA_Human1.48844775
42EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.46177996
43TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.45967306
44CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.37495765
45* RARB_27405468_Chip-Seq_BRAIN_Mouse1.37479667
46GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.36326488
47ZNF274_21170338_ChIP-Seq_K562_Hela1.34064840
48PCGF2_27294783_Chip-Seq_ESCs_Mouse1.33855021
49SMAD3_21741376_ChIP-Seq_EPCs_Human1.33247611
50POU3F2_20337985_ChIP-ChIP_501MEL_Human1.31181548
51RING1B_27294783_Chip-Seq_ESCs_Mouse1.31103717
52RING1B_27294783_Chip-Seq_NPCs_Mouse1.30071807
53CDX2_19796622_ChIP-Seq_MESCs_Mouse1.29764279
54SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.29686389
55MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.27724891
56GATA1_26923725_Chip-Seq_HPCs_Mouse1.26257842
57FUS_26573619_Chip-Seq_HEK293_Human1.25610702
58FLI1_27457419_Chip-Seq_LIVER_Mouse1.24787409
59SMAD4_21799915_ChIP-Seq_A2780_Human1.24461135
60MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.23995307
61HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.19941520
62SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.19387480
63* SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.17279992
64FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.16071670
65NANOG_18555785_Chip-Seq_ESCs_Mouse1.14058958
66TOP2B_26459242_ChIP-Seq_MCF-7_Human1.13712969
67POU5F1_16153702_ChIP-ChIP_HESCs_Human1.11965554
68CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.11549548
69ER_23166858_ChIP-Seq_MCF-7_Human1.10816707
70PIAS1_25552417_ChIP-Seq_VCAP_Human1.10618138
71OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.09269394
72TP53_20018659_ChIP-ChIP_R1E_Mouse1.08646856
73TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.07363048
74SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07278405
75EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.07197600
76AR_25329375_ChIP-Seq_VCAP_Human1.06404589
77ERG_21242973_ChIP-ChIP_JURKAT_Human1.03711259
78SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.03556943
79* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.02616312
80E2F1_18555785_Chip-Seq_ESCs_Mouse1.01162601
81P53_22387025_ChIP-Seq_ESCs_Mouse1.01114889
82SUZ12_27294783_Chip-Seq_NPCs_Mouse0.99999611
83VDR_22108803_ChIP-Seq_LS180_Human0.99952468
84* RUNX2_22187159_ChIP-Seq_PCA_Human0.99905627
85MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.99746033
86DNAJC2_21179169_ChIP-ChIP_NT2_Human0.98184340
87TP53_22573176_ChIP-Seq_HFKS_Human0.97754766
88CMYC_18555785_Chip-Seq_ESCs_Mouse0.97012825
89EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.96538919
90TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96504995
91POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.96504995
92AR_19668381_ChIP-Seq_PC3_Human0.96494175
93SUZ12_18555785_Chip-Seq_ESCs_Mouse0.96232027
94SMAD3_21741376_ChIP-Seq_ESCs_Human0.95530782
95CBP_20019798_ChIP-Seq_JUKART_Human0.93773946
96IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.93773946
97P300_18555785_Chip-Seq_ESCs_Mouse0.93610940
98LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.93440898
99E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.93404281
100ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.93097403
101KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.93024978
102SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.91988018
103TCF4_23295773_ChIP-Seq_U87_Human0.91638661
104SMAD_19615063_ChIP-ChIP_OVARY_Human0.91394546
105NFE2_27457419_Chip-Seq_LIVER_Mouse0.90561344
106RUNX1_27457419_Chip-Seq_LIVER_Mouse0.90129715
107SOX2_21211035_ChIP-Seq_LN229_Gbm0.89970286
108TAL1_26923725_Chip-Seq_HPCs_Mouse0.89765514
109CTCF_27219007_Chip-Seq_Bcells_Human0.88992528
110JUN_21703547_ChIP-Seq_K562_Human0.88704548
111STAT3_18555785_Chip-Seq_ESCs_Mouse0.88677697
112ETV2_25802403_ChIP-Seq_MESCs_Mouse0.88579317
113TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.88362649
114NMYC_18555785_Chip-Seq_ESCs_Mouse0.88315020
115CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.88139600
116UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.88126621
117RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.88101708
118KDM2B_26808549_Chip-Seq_REH_Human0.88026585
119CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.88022452
120EWS_26573619_Chip-Seq_HEK293_Human0.87803844
121P53_22127205_ChIP-Seq_FIBROBLAST_Human0.87375249
122MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.86518152
123TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86273977
124IRF1_19129219_ChIP-ChIP_H3396_Human0.86167618
125* PRDM14_20953172_ChIP-Seq_ESCs_Human0.85034263
126STAT3_23295773_ChIP-Seq_U87_Human0.84946227
127* GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.84279071
128KLF5_20875108_ChIP-Seq_MESCs_Mouse0.82481914
129SOX9_26525672_Chip-Seq_HEART_Mouse0.82029954

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.33759952
2MP0004859_abnormal_synaptic_plasticity4.00848994
3MP0001188_hyperpigmentation3.33324470
4MP0003136_yellow_coat_color3.18029217
5MP0005409_darkened_coat_color3.13953626
6MP0003635_abnormal_synaptic_transmissio3.07187444
7MP0009379_abnormal_foot_pigmentation3.00623027
8MP0006292_abnormal_olfactory_placode2.94912860
9MP0004270_analgesia2.87047229
10MP0005423_abnormal_somatic_nervous2.86493140
11MP0009745_abnormal_behavioral_response2.70067234
12MP0001968_abnormal_touch/_nociception2.50163277
13MP0001486_abnormal_startle_reflex2.38253937
14MP0002063_abnormal_learning/memory/cond2.36212150
15MP0002064_seizures2.32947803
16MP0006276_abnormal_autonomic_nervous2.24497561
17MP0009046_muscle_twitch2.24199887
18MP0002572_abnormal_emotion/affect_behav2.18152080
19MP0002272_abnormal_nervous_system2.17081967
20MP0000778_abnormal_nervous_system2.16775521
21MP0002734_abnormal_mechanical_nocicepti2.05593195
22MP0002184_abnormal_innervation1.92212406
23MP0000015_abnormal_ear_pigmentation1.90989897
24MP0002102_abnormal_ear_morphology1.88337595
25MP0008877_abnormal_DNA_methylation1.85484818
26MP0005174_abnormal_tail_pigmentation1.85454059
27MP0002557_abnormal_social/conspecific_i1.83763368
28MP0002067_abnormal_sensory_capabilities1.80431529
29MP0002736_abnormal_nociception_after1.74212107
30MP0002735_abnormal_chemical_nociception1.73573725
31MP0003121_genomic_imprinting1.70872222
32MP0004381_abnormal_hair_follicle1.68795491
33MP0001529_abnormal_vocalization1.66954441
34MP0001970_abnormal_pain_threshold1.65144851
35MP0004142_abnormal_muscle_tone1.64130308
36MP0002733_abnormal_thermal_nociception1.59554030
37MP0001440_abnormal_grooming_behavior1.58427642
38MP0001905_abnormal_dopamine_level1.57540192
39MP0008569_lethality_at_weaning1.52016057
40MP0004742_abnormal_vestibular_system1.50989690
41MP0000631_abnormal_neuroendocrine_gland1.50111013
42MP0003938_abnormal_ear_development1.47728566
43MP0003879_abnormal_hair_cell1.47600651
44MP0003123_paternal_imprinting1.46275900
45MP0001501_abnormal_sleep_pattern1.45334122
46MP0001984_abnormal_olfaction1.44368764
47MP0005645_abnormal_hypothalamus_physiol1.43892655
48MP0002638_abnormal_pupillary_reflex1.40614165
49MP0002822_catalepsy1.40431041
50MP0000955_abnormal_spinal_cord1.37924602
51MP0002751_abnormal_autonomic_nervous1.37329850
52MP0002882_abnormal_neuron_morphology1.33743869
53MP0005646_abnormal_pituitary_gland1.31433941
54MP0002876_abnormal_thyroid_physiology1.24777144
55MP0003283_abnormal_digestive_organ1.23610538
56MP0000026_abnormal_inner_ear1.22289804
57MP0000049_abnormal_middle_ear1.21795863
58MP0002752_abnormal_somatic_nervous1.18942775
59MP0004811_abnormal_neuron_physiology1.16471944
60MP0001963_abnormal_hearing_physiology1.16414764
61MP0004885_abnormal_endolymph1.16121211
62MP0005386_behavior/neurological_phenoty1.15404149
63MP0004924_abnormal_behavior1.15404149
64MP0005499_abnormal_olfactory_system1.15238210
65MP0005394_taste/olfaction_phenotype1.15238210
66MP0005171_absent_coat_pigmentation1.12947938
67MP0001986_abnormal_taste_sensitivity1.12164855
68MP0002066_abnormal_motor_capabilities/c1.11927215
69MP0002653_abnormal_ependyma_morphology1.11722789
70MP0004145_abnormal_muscle_electrophysio1.05331988
71MP0001502_abnormal_circadian_rhythm1.04964541
72MP0008872_abnormal_physiological_respon1.04425295
73MP0005187_abnormal_penis_morphology1.03186535
74MP0002234_abnormal_pharynx_morphology1.02992090
75MP0001485_abnormal_pinna_reflex1.02365997
76MP0002152_abnormal_brain_morphology1.02219467
77MP0000372_irregular_coat_pigmentation1.01933439
78MP0002249_abnormal_larynx_morphology1.01092963
79MP0008789_abnormal_olfactory_epithelium1.00637782
80MP0005551_abnormal_eye_electrophysiolog1.00087272
81MP0002177_abnormal_outer_ear0.96919220
82MP0002095_abnormal_skin_pigmentation0.93406943
83MP0000681_abnormal_thyroid_gland0.93046213
84MP0005075_abnormal_melanosome_morpholog0.90469938
85MP0002229_neurodegeneration0.86637435
86MP0000920_abnormal_myelination0.86601014
87MP0003315_abnormal_perineum_morphology0.86136273
88MP0001664_abnormal_digestion0.85537529
89MP0001177_atelectasis0.85438693
90MP0008995_early_reproductive_senescence0.84779949
91MP0003119_abnormal_digestive_system0.83427126
92MP0004043_abnormal_pH_regulation0.82061520
93MP0002909_abnormal_adrenal_gland0.81332077
94MP0010386_abnormal_urinary_bladder0.80384122
95MP0000566_synostosis0.79115937
96MP0003787_abnormal_imprinting0.77590561
97MP0008260_abnormal_autophagy0.76856537
98MP0006072_abnormal_retinal_apoptosis0.76508805
99MP0001348_abnormal_lacrimal_gland0.75909991
100MP0003122_maternal_imprinting0.75722254
101MP0003861_abnormal_nervous_system0.75373988
102MP0002277_abnormal_respiratory_mucosa0.73899094
103MP0003646_muscle_fatigue0.71175278
104MP0004133_heterotaxia0.70752144
105MP0003329_amyloid_beta_deposits0.66735044
106MP0009780_abnormal_chondrocyte_physiolo0.65467165
107MP0002082_postnatal_lethality0.64270038
108MP0010770_preweaning_lethality0.64270038
109MP0005253_abnormal_eye_physiology0.64165560
110MP0005195_abnormal_posterior_eye0.63776386
111MP0010769_abnormal_survival0.63236457
112MP0003942_abnormal_urinary_system0.63048940
113MP0002210_abnormal_sex_determination0.62342503
114MP0002081_perinatal_lethality0.61833526
115MP0001943_abnormal_respiration0.61331257
116MP0005084_abnormal_gallbladder_morpholo0.61197225
117MP0003633_abnormal_nervous_system0.61088474
118MP0003634_abnormal_glial_cell0.60939514
119MP0002069_abnormal_eating/drinking_beha0.59093330
120MP0003698_abnormal_male_reproductive0.57234227
121MP0002938_white_spotting0.57148261
122MP0003631_nervous_system_phenotype0.55725428
123MP0009250_abnormal_appendicular_skeleto0.55242448
124MP0003385_abnormal_body_wall0.54587798

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.31019114
2Myokymia (HP:0002411)4.57150168
3Focal seizures (HP:0007359)3.59976603
4Nonprogressive disorder (HP:0003680)3.53693132
5Febrile seizures (HP:0002373)3.46234014
6Broad-based gait (HP:0002136)3.24039537
7Type I transferrin isoform profile (HP:0003642)3.19532947
8Epileptic encephalopathy (HP:0200134)3.11890745
9Progressive inability to walk (HP:0002505)2.97990733
10Progressive cerebellar ataxia (HP:0002073)2.93165889
11Absent/shortened dynein arms (HP:0200106)2.91406057
12Dynein arm defect of respiratory motile cilia (HP:0012255)2.91406057
13Hemiparesis (HP:0001269)2.88044754
14Thyroid-stimulating hormone excess (HP:0002925)2.76736569
15Atonic seizures (HP:0010819)2.76258340
16Pachygyria (HP:0001302)2.73923058
17Hypothermia (HP:0002045)2.72025656
18Type II lissencephaly (HP:0007260)2.71969826
19Abnormality of the labia minora (HP:0012880)2.70514743
20Gaze-evoked nystagmus (HP:0000640)2.68929297
21Limb dystonia (HP:0002451)2.65868515
22Epileptiform EEG discharges (HP:0011182)2.65585767
23Visual hallucinations (HP:0002367)2.58426046
24Hypsarrhythmia (HP:0002521)2.57529263
25EEG with generalized epileptiform discharges (HP:0011198)2.55999565
26Urinary bladder sphincter dysfunction (HP:0002839)2.46853434
27Abnormal ciliary motility (HP:0012262)2.46479798
28Dialeptic seizures (HP:0011146)2.45458045
29Reduced antithrombin III activity (HP:0001976)2.45437239
30Absent rod-and cone-mediated responses on ERG (HP:0007688)2.44382574
31Parakeratosis (HP:0001036)2.44117680
32Pancreatic cysts (HP:0001737)2.43068653
33Abnormality of the axillary hair (HP:0100134)2.41933677
34Abnormality of secondary sexual hair (HP:0009888)2.41933677
35Peripheral hypomyelination (HP:0007182)2.38722851
36Spastic gait (HP:0002064)2.37946883
37Abnormality of the corticospinal tract (HP:0002492)2.37484962
38Urinary urgency (HP:0000012)2.36694691
39Esotropia (HP:0000565)2.36376076
40Abnormal respiratory epithelium morphology (HP:0012253)2.35327773
41Abnormal respiratory motile cilium morphology (HP:0005938)2.35327773
42Hyperventilation (HP:0002883)2.33783163
43Cerebral hypomyelination (HP:0006808)2.33266056
44Increased hepatocellular lipid droplets (HP:0006565)2.32781142
45Hypoplasia of the brainstem (HP:0002365)2.32371723
46Aplasia/Hypoplasia of the brainstem (HP:0007362)2.32371723
47Concave nail (HP:0001598)2.29483403
48Sleep apnea (HP:0010535)2.29215862
49Inability to walk (HP:0002540)2.29170027
50True hermaphroditism (HP:0010459)2.26593944
51Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.26237482
52Absence seizures (HP:0002121)2.26222125
53Obstructive sleep apnea (HP:0002870)2.24582988
54Impaired vibration sensation in the lower limbs (HP:0002166)2.23520178
55Renal Fanconi syndrome (HP:0001994)2.23181113
56Split foot (HP:0001839)2.22594779
57Severe visual impairment (HP:0001141)2.22306317
58Nephronophthisis (HP:0000090)2.21513547
59Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.20680837
60Mutism (HP:0002300)2.19970197
61Polyphagia (HP:0002591)2.19867135
62Absent septum pellucidum (HP:0001331)2.19248558
63Abnormality of midbrain morphology (HP:0002418)2.17789212
64Molar tooth sign on MRI (HP:0002419)2.17789212
65Retinal dysplasia (HP:0007973)2.15548393
66Drooling (HP:0002307)2.14550837
67Excessive salivation (HP:0003781)2.14550837
68Absent speech (HP:0001344)2.14402476
69Abnormality of magnesium homeostasis (HP:0004921)2.13382787
70Optic disc pallor (HP:0000543)2.13024380
71Optic nerve hypoplasia (HP:0000609)2.13009710
72Agitation (HP:0000713)2.12286320
73Generalized tonic-clonic seizures (HP:0002069)2.12213882
74Status epilepticus (HP:0002133)2.12140401
75Cortical visual impairment (HP:0100704)2.11939313
76Chronic hepatic failure (HP:0100626)2.09447808
77Torticollis (HP:0000473)2.09348963
78Spastic tetraplegia (HP:0002510)2.08688587
79Attenuation of retinal blood vessels (HP:0007843)2.06219525
80Action tremor (HP:0002345)2.06098023
81Ulnar claw (HP:0001178)2.06095735
82Gait imbalance (HP:0002141)2.05133635
833-Methylglutaconic aciduria (HP:0003535)2.04721191
84Abnormal respiratory motile cilium physiology (HP:0012261)1.98191451
85Anxiety (HP:0000739)1.98012478
86Septo-optic dysplasia (HP:0100842)1.97752782
87Nephrogenic diabetes insipidus (HP:0009806)1.96379101
88Amblyopia (HP:0000646)1.96111672
89Congenital primary aphakia (HP:0007707)1.95293810
90Pendular nystagmus (HP:0012043)1.95280887
91Abnormality of the septum pellucidum (HP:0007375)1.94676096
92Genetic anticipation (HP:0003743)1.94287149
93Diplopia (HP:0000651)1.91544173
94Abnormality of binocular vision (HP:0011514)1.91544173
95CNS hypomyelination (HP:0003429)1.90891788
96Morphological abnormality of the pyramidal tract (HP:0002062)1.90874740
97Abnormality of cells of the erythroid lineage (HP:0012130)1.89779637
98Abnormal sex determination (HP:0012244)1.88353327
99Sex reversal (HP:0012245)1.88353327
100Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.87783226
101Amyotrophic lateral sclerosis (HP:0007354)1.87509709
102Abnormal eating behavior (HP:0100738)1.86785522
103Decreased central vision (HP:0007663)1.85958761
104Akinesia (HP:0002304)1.85908334
105Medial flaring of the eyebrow (HP:0010747)1.84398114
106Poor suck (HP:0002033)1.83633280
107Poor eye contact (HP:0000817)1.83294798
108Supernumerary spleens (HP:0009799)1.81987210
109Sclerocornea (HP:0000647)1.81072227
110Cerebellar dysplasia (HP:0007033)1.80325403
111Abnormal number of erythroid precursors (HP:0012131)1.80019304
112Fetal akinesia sequence (HP:0001989)1.79563227
113Methylmalonic acidemia (HP:0002912)1.78683618
114Focal dystonia (HP:0004373)1.78634138
115Ankle clonus (HP:0011448)1.77742039
116Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.77156938
117Hypoplasia of the corpus callosum (HP:0002079)1.76926654
118Dysmetria (HP:0001310)1.76692598
119Sensory axonal neuropathy (HP:0003390)1.75888965
120Genital tract atresia (HP:0001827)1.75848769
121Protruding tongue (HP:0010808)1.75299082
122Abnormal rod and cone electroretinograms (HP:0008323)1.74291113
123Oligodactyly (hands) (HP:0001180)1.74008049
124Megalencephaly (HP:0001355)1.73939891
125Type 2 muscle fiber atrophy (HP:0003554)1.73537904
126Degeneration of the lateral corticospinal tracts (HP:0002314)1.73175122
127Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.73175122
128Abnormal protein glycosylation (HP:0012346)1.72957846
129Abnormal glycosylation (HP:0012345)1.72957846
130Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.72957846
131Abnormal protein N-linked glycosylation (HP:0012347)1.72957846
132Depression (HP:0000716)1.72797334
133Pancreatic fibrosis (HP:0100732)1.72368524
134Lissencephaly (HP:0001339)1.72365243
135Scanning speech (HP:0002168)1.72206989
136Mitochondrial inheritance (HP:0001427)1.71680017
137Unsteady gait (HP:0002317)1.71507200
138Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.71146252
139Postural instability (HP:0002172)1.71073739
140Vaginal atresia (HP:0000148)1.70247302
141Acute necrotizing encephalopathy (HP:0006965)1.66926917
142Polymicrogyria (HP:0002126)1.66707589
143Patellar aplasia (HP:0006443)1.66441200
144Specific learning disability (HP:0001328)1.66262780
145Congenital stationary night blindness (HP:0007642)1.66108645
146Stereotypic behavior (HP:0000733)1.66093694
147Failure to thrive in infancy (HP:0001531)1.65985345
148Short tibia (HP:0005736)1.65844562
149Supranuclear gaze palsy (HP:0000605)1.65608768
150Optic nerve coloboma (HP:0000588)1.63298040
151Shawl scrotum (HP:0000049)1.62663797
152Abnormality of the renal medulla (HP:0100957)1.62463859
153Methylmalonic aciduria (HP:0012120)1.59318110
154Abnormal mitochondria in muscle tissue (HP:0008316)1.57396253

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.33331533
2TNIK5.32423273
3MUSK3.97490478
4MARK13.58960845
5EPHA42.85686760
6MAP2K72.57721711
7NTRK32.57016775
8MAPK132.42644390
9MKNK22.30812311
10PINK12.15442745
11CDK192.11567756
12FES1.89708521
13STK161.71614040
14NTRK21.71375601
15CCNB11.67051024
16WNK41.57841531
17SIK21.57469073
18PRPF4B1.56672867
19TYRO31.55372804
20DYRK21.55070801
21PRKD31.53001835
22UHMK11.50861313
23MKNK11.49357509
24MAP3K121.46905066
25FRK1.45116393
26MINK11.24800705
27MAP4K21.24489358
28PAK31.23152468
29TLK11.21107049
30CAMK11.17573429
31ADRBK21.17403612
32RIPK41.11214961
33MAP3K41.08772351
34OXSR11.08353488
35CAMKK21.08089865
36CDK51.04915629
37NTRK11.04565365
38ZAK1.03259456
39DAPK21.01278561
40SRPK10.99995512
41CAMK2B0.99463569
42YES10.97462110
43PRKD20.96667933
44MAP3K90.96576662
45FGR0.95946090
46CSNK1G20.93978514
47STK390.93753979
48IRAK20.93677984
49CAMK1G0.93612064
50CSNK1G30.91651981
51TRIM280.89551467
52GRK50.88933702
53MARK20.87690268
54CAMK2A0.86895558
55PHKG10.84418654
56PHKG20.84418654
57CLK10.83815121
58GRK70.83725793
59PNCK0.83213382
60DYRK1A0.81548858
61CSNK1G10.79119079
62WNK30.78603539
63PKN10.78550619
64EIF2AK20.76775528
65PRKCZ0.76455635
66PRKCH0.76153849
67NME20.75949636
68BMPR20.74286468
69PRKCG0.74068663
70PAK60.73019608
71EPHB20.71919674
72CDK30.70777418
73BMPR1B0.69810048
74NME10.69520099
75SIK30.69054788
76CSNK1A1L0.68979591
77CDC70.66991141
78CAMK1D0.66783206
79NLK0.66730235
80CAMKK10.65173258
81MAPKAPK50.59371308
82STK110.58480576
83LIMK10.57688510
84KSR10.57606303
85NEK60.57258093
86CSNK1D0.57036696
87INSRR0.56910607
88ARAF0.56656225
89CDK140.56580352
90CDK11A0.56116224
91VRK10.55446990
92CDK180.55115472
93PLK40.54478051
94BRSK10.53922463
95CSNK1E0.53691164
96PRKCI0.53465418
97BLK0.53309476
98CDK150.53200919
99DAPK10.53180347
100CHEK20.52974162
101IRAK40.52073887
102MAP2K40.51468758
103BCR0.51314705
104ALK0.49260616
105CSNK1A10.49030664
106PLK20.48833411
107GRK10.47482882
108PRKCE0.47270613
109CAMK40.47027398
110BCKDK0.46395582
111TNK20.44173617
112MAPK40.44137873
113ADRBK10.43658659
114SGK2230.42967977
115SGK4940.42967977
116PRKG10.41358645
117IRAK10.41185647
118AURKA0.40120233
119RPS6KA30.38268012
120STK380.38062809
121DYRK30.37848753
122NUAK10.36868813
123FGFR20.36799592
124PRKACA0.36228753
125MAP2K60.35823364
126GSK3B0.35241560
127MAPK120.34512943
128CAMK2G0.34450752
129MAP3K110.34258110
130CAMK2D0.34015945
131LATS20.33586156
132RAF10.33409810
133SGK10.32230760
134MAPK150.29815209
135FYN0.29810193

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.97832372
2Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.74921198
3Glutamatergic synapse_Homo sapiens_hsa047242.56853099
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.51881975
5Morphine addiction_Homo sapiens_hsa050322.43652024
6GABAergic synapse_Homo sapiens_hsa047272.26619426
7Olfactory transduction_Homo sapiens_hsa047402.21529212
8Circadian entrainment_Homo sapiens_hsa047132.17734025
9Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.10357569
10Serotonergic synapse_Homo sapiens_hsa047262.06184236
11Synaptic vesicle cycle_Homo sapiens_hsa047212.04878361
12Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.98369047
13Phototransduction_Homo sapiens_hsa047441.97288485
14Taste transduction_Homo sapiens_hsa047421.94126338
15Oxidative phosphorylation_Homo sapiens_hsa001901.80319344
16Ribosome_Homo sapiens_hsa030101.79310050
17Amphetamine addiction_Homo sapiens_hsa050311.78777263
18Long-term depression_Homo sapiens_hsa047301.77025889
19Axon guidance_Homo sapiens_hsa043601.76306571
20Long-term potentiation_Homo sapiens_hsa047201.74562171
21Dopaminergic synapse_Homo sapiens_hsa047281.72304757
22Cholinergic synapse_Homo sapiens_hsa047251.64492648
23Salivary secretion_Homo sapiens_hsa049701.62745015
24Cocaine addiction_Homo sapiens_hsa050301.50156020
25Calcium signaling pathway_Homo sapiens_hsa040201.48662998
26Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.44135066
27Alzheimers disease_Homo sapiens_hsa050101.40417969
28Parkinsons disease_Homo sapiens_hsa050121.39388382
29Aldosterone synthesis and secretion_Homo sapiens_hsa049251.32497866
30Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.31146634
31Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.25784265
32Insulin secretion_Homo sapiens_hsa049111.19189748
33Oxytocin signaling pathway_Homo sapiens_hsa049211.18405031
34Renin secretion_Homo sapiens_hsa049241.17892059
35Cardiac muscle contraction_Homo sapiens_hsa042601.17445762
36Gap junction_Homo sapiens_hsa045401.15223664
37Gastric acid secretion_Homo sapiens_hsa049711.10263058
38Melanogenesis_Homo sapiens_hsa049161.09746463
39Huntingtons disease_Homo sapiens_hsa050161.09257435
40Butanoate metabolism_Homo sapiens_hsa006501.08119907
41Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.06230750
42Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.03720830
43Collecting duct acid secretion_Homo sapiens_hsa049661.03615017
44Selenocompound metabolism_Homo sapiens_hsa004501.00968230
45Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.99601898
46cAMP signaling pathway_Homo sapiens_hsa040240.99146917
47Wnt signaling pathway_Homo sapiens_hsa043100.98781215
48Ether lipid metabolism_Homo sapiens_hsa005650.98619976
49Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.97765344
50Vitamin B6 metabolism_Homo sapiens_hsa007500.96777047
51GnRH signaling pathway_Homo sapiens_hsa049120.95975957
52Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.94092104
53Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.92100216
54Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.91289411
55Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.88641439
56Alcoholism_Homo sapiens_hsa050340.88335447
57Sphingolipid metabolism_Homo sapiens_hsa006000.87023371
58Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.85043384
59Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.84165941
60ErbB signaling pathway_Homo sapiens_hsa040120.77020913
61Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.71998506
62alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.71786253
63SNARE interactions in vesicular transport_Homo sapiens_hsa041300.71190427
64Fanconi anemia pathway_Homo sapiens_hsa034600.70172551
65Ras signaling pathway_Homo sapiens_hsa040140.69581617
66Vascular smooth muscle contraction_Homo sapiens_hsa042700.69204088
67Regulation of autophagy_Homo sapiens_hsa041400.67823419
68Hippo signaling pathway_Homo sapiens_hsa043900.67531653
69Phospholipase D signaling pathway_Homo sapiens_hsa040720.67241099
70Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.65496746
71Basal cell carcinoma_Homo sapiens_hsa052170.62052256
72Sphingolipid signaling pathway_Homo sapiens_hsa040710.58911628
73Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.58188022
74Linoleic acid metabolism_Homo sapiens_hsa005910.56449293
75Vibrio cholerae infection_Homo sapiens_hsa051100.55327737
76African trypanosomiasis_Homo sapiens_hsa051430.53113887
77MAPK signaling pathway_Homo sapiens_hsa040100.52736580
78Choline metabolism in cancer_Homo sapiens_hsa052310.52352383
79Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.52245796
80Ovarian steroidogenesis_Homo sapiens_hsa049130.52055162
81N-Glycan biosynthesis_Homo sapiens_hsa005100.51637430
82beta-Alanine metabolism_Homo sapiens_hsa004100.51605121
83Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.51273250
84Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.50842645
85Protein export_Homo sapiens_hsa030600.50627228
86Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.50501786
87Phosphatidylinositol signaling system_Homo sapiens_hsa040700.50452991
88Arginine and proline metabolism_Homo sapiens_hsa003300.49853719
89Pancreatic secretion_Homo sapiens_hsa049720.48617579
90Hedgehog signaling pathway_Homo sapiens_hsa043400.48296481
91Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.47877374
92mRNA surveillance pathway_Homo sapiens_hsa030150.47780220
93Sulfur relay system_Homo sapiens_hsa041220.47713587
94Rheumatoid arthritis_Homo sapiens_hsa053230.47680419
95Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.47513954
96cGMP-PKG signaling pathway_Homo sapiens_hsa040220.46623140
97Arachidonic acid metabolism_Homo sapiens_hsa005900.44585330
98Autoimmune thyroid disease_Homo sapiens_hsa053200.43945867
99Type II diabetes mellitus_Homo sapiens_hsa049300.43413364
100Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.42942607
101Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.42831344
102Type I diabetes mellitus_Homo sapiens_hsa049400.42275167
103Rap1 signaling pathway_Homo sapiens_hsa040150.42216377
104Purine metabolism_Homo sapiens_hsa002300.42104874
105Folate biosynthesis_Homo sapiens_hsa007900.42082292
106Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.38779210
107Nitrogen metabolism_Homo sapiens_hsa009100.38283849
108Asthma_Homo sapiens_hsa053100.37310476
109Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.36757016
110Chemokine signaling pathway_Homo sapiens_hsa040620.35934811
111Estrogen signaling pathway_Homo sapiens_hsa049150.35876255
112Steroid biosynthesis_Homo sapiens_hsa001000.35701805
113Thyroid hormone synthesis_Homo sapiens_hsa049180.35683033
114Homologous recombination_Homo sapiens_hsa034400.35277933
115Basal transcription factors_Homo sapiens_hsa030220.33810695
116Graft-versus-host disease_Homo sapiens_hsa053320.33296986
117Colorectal cancer_Homo sapiens_hsa052100.31792773
118Allograft rejection_Homo sapiens_hsa053300.31745228
119RNA degradation_Homo sapiens_hsa030180.30548348
120RNA polymerase_Homo sapiens_hsa030200.29825792
121AMPK signaling pathway_Homo sapiens_hsa041520.29390301
122Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.28671707
123Cyanoamino acid metabolism_Homo sapiens_hsa004600.28591318
124Melanoma_Homo sapiens_hsa052180.28462826
125Dilated cardiomyopathy_Homo sapiens_hsa054140.28443321
126Dorso-ventral axis formation_Homo sapiens_hsa043200.28278346
127Glioma_Homo sapiens_hsa052140.27787968
128Spliceosome_Homo sapiens_hsa030400.26514979
129Oocyte meiosis_Homo sapiens_hsa041140.26144052
130Circadian rhythm_Homo sapiens_hsa047100.25839314

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