DNAJC25

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)5.65525646
2L-phenylalanine catabolic process (GO:0006559)5.65525646
3aromatic amino acid family catabolic process (GO:0009074)5.59234040
4indole-containing compound catabolic process (GO:0042436)5.56083734
5indolalkylamine catabolic process (GO:0046218)5.56083734
6tryptophan catabolic process (GO:0006569)5.56083734
7L-phenylalanine metabolic process (GO:0006558)5.30510555
8erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)5.30510555
9tryptophan metabolic process (GO:0006568)5.24468369
10cellular glucuronidation (GO:0052695)4.97200646
11kynurenine metabolic process (GO:0070189)4.77028665
12triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.73191401
13uronic acid metabolic process (GO:0006063)4.64929703
14glucuronate metabolic process (GO:0019585)4.64929703
15peptidyl-glutamic acid carboxylation (GO:0017187)4.63912599
16protein carboxylation (GO:0018214)4.63912599
17glyoxylate metabolic process (GO:0046487)4.50412796
18regulation of fibrinolysis (GO:0051917)4.49947414
19amine catabolic process (GO:0009310)4.42000898
20cellular biogenic amine catabolic process (GO:0042402)4.42000898
21urea cycle (GO:0000050)4.25118246
22urea metabolic process (GO:0019627)4.25118246
23bile acid biosynthetic process (GO:0006699)4.14970788
24negative regulation of fibrinolysis (GO:0051918)4.14495887
25high-density lipoprotein particle remodeling (GO:0034375)4.12099575
26regulation of protein activation cascade (GO:2000257)4.08863638
27aromatic amino acid family metabolic process (GO:0009072)4.00409683
28nitrogen cycle metabolic process (GO:0071941)3.99325164
29serine family amino acid catabolic process (GO:0009071)3.96921966
30indolalkylamine metabolic process (GO:0006586)3.96223887
31homocysteine metabolic process (GO:0050667)3.94219395
32regulation of plasminogen activation (GO:0010755)3.93806866
33blood coagulation, intrinsic pathway (GO:0007597)3.90084343
34complement activation, alternative pathway (GO:0006957)3.90080957
35regulation of triglyceride catabolic process (GO:0010896)3.87140758
36fibrinolysis (GO:0042730)3.84346232
37acylglycerol homeostasis (GO:0055090)3.84065545
38triglyceride homeostasis (GO:0070328)3.84065545
39regulation of complement activation (GO:0030449)3.82406412
40regulation of cholesterol esterification (GO:0010872)3.75025137
41amino-acid betaine metabolic process (GO:0006577)3.73007382
42aldehyde catabolic process (GO:0046185)3.72819660
43regulation of heterotypic cell-cell adhesion (GO:0034114)3.67524008
44bile acid metabolic process (GO:0008206)3.64445080
45protein-lipid complex remodeling (GO:0034368)3.54084843
46macromolecular complex remodeling (GO:0034367)3.54084843
47plasma lipoprotein particle remodeling (GO:0034369)3.54084843
48alpha-amino acid catabolic process (GO:1901606)3.51907360
49reverse cholesterol transport (GO:0043691)3.47913246
50imidazole-containing compound metabolic process (GO:0052803)3.46704182
51proteasome assembly (GO:0043248)3.43432751
52tyrosine metabolic process (GO:0006570)3.42612643
53opsonization (GO:0008228)3.40865937
54regulation of DNA endoreduplication (GO:0032875)3.40857832
55regulation of protein polyubiquitination (GO:1902914)3.39665531
56regulation of cytokine secretion involved in immune response (GO:0002739)3.39623095
57NAD biosynthetic process (GO:0009435)3.38232460
58fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.37854070
59bile acid and bile salt transport (GO:0015721)3.36201562
60glycine metabolic process (GO:0006544)3.35891824
61phospholipid efflux (GO:0033700)3.35838671
62negative regulation of lipase activity (GO:0060192)3.34619950
63sulfur amino acid catabolic process (GO:0000098)3.34243622
64coenzyme catabolic process (GO:0009109)3.34123580
65cysteine metabolic process (GO:0006534)3.33887631
66plasma lipoprotein particle assembly (GO:0034377)3.29753558
67ribosome assembly (GO:0042255)3.27228886
68drug catabolic process (GO:0042737)3.26055324
69negative regulation of DNA-dependent DNA replication (GO:2000104)3.25739541
70phenylpropanoid metabolic process (GO:0009698)3.21756486
71cellular amino acid catabolic process (GO:0009063)3.14623408
72protein activation cascade (GO:0072376)3.13958145
73benzene-containing compound metabolic process (GO:0042537)3.12507210
74regulation of bile acid biosynthetic process (GO:0070857)3.09146359
75negative regulation of blood coagulation (GO:0030195)3.08692571
76negative regulation of hemostasis (GO:1900047)3.08692571
77copper ion homeostasis (GO:0055070)3.05249513
78cellular ketone body metabolic process (GO:0046950)3.05141398
79serine family amino acid biosynthetic process (GO:0009070)3.04282062
80exogenous drug catabolic process (GO:0042738)3.03831895
81serine family amino acid metabolic process (GO:0009069)3.03550416
82protein-lipid complex assembly (GO:0065005)3.02271772
83mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.00821427
84positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.99799868
85positive regulation of fatty acid beta-oxidation (GO:0032000)2.99649728
86mitotic sister chromatid cohesion (GO:0007064)2.98406713
87plasma lipoprotein particle clearance (GO:0034381)2.97829245
88cofactor catabolic process (GO:0051187)2.96921464
89negative regulation of wound healing (GO:0061045)2.96640906
90pyridine nucleotide biosynthetic process (GO:0019363)2.96456625
91nicotinamide nucleotide biosynthetic process (GO:0019359)2.96456625
92cholesterol efflux (GO:0033344)2.95557972
93positive regulation of lipid catabolic process (GO:0050996)2.94357107
94arginine metabolic process (GO:0006525)2.93056104
95organic acid catabolic process (GO:0016054)2.92124470
96carboxylic acid catabolic process (GO:0046395)2.92124470
97establishment of protein localization to mitochondrial membrane (GO:0090151)2.91966554
98cellular modified amino acid catabolic process (GO:0042219)2.91868443
99intestinal cholesterol absorption (GO:0030299)2.91438782
100alpha-linolenic acid metabolic process (GO:0036109)2.91353698
101carnitine metabolic process (GO:0009437)2.91138755
102negative regulation of sterol transport (GO:0032372)2.90890864
103negative regulation of cholesterol transport (GO:0032375)2.90890864
104purine ribonucleotide transport (GO:0015868)2.90733975
105low-density lipoprotein particle remodeling (GO:0034374)2.90595098
106acute-phase response (GO:0006953)2.90342649
107omega-hydroxylase P450 pathway (GO:0097267)2.90211739
108very-low-density lipoprotein particle assembly (GO:0034379)2.87455840
109negative regulation of coagulation (GO:0050819)2.84856111
110lysine catabolic process (GO:0006554)2.84102854
111lysine metabolic process (GO:0006553)2.84102854
112complement activation (GO:0006956)2.83569269
113nucleotide transmembrane transport (GO:1901679)2.82652845
114complement activation, classical pathway (GO:0006958)2.82468206
115L-methionine salvage (GO:0071267)2.81348077
116L-methionine biosynthetic process (GO:0071265)2.81348077
117amino acid salvage (GO:0043102)2.81348077
118ER overload response (GO:0006983)2.80921538
119fatty acid beta-oxidation (GO:0006635)2.80256003
120oxidative demethylation (GO:0070989)2.77993339
121L-ascorbic acid metabolic process (GO:0019852)2.77231427
122epoxygenase P450 pathway (GO:0019373)2.76858913
123water-soluble vitamin biosynthetic process (GO:0042364)2.76493478
124chromatin remodeling at centromere (GO:0031055)2.69338894
125regulation of centriole replication (GO:0046599)2.69135649
126UDP-N-acetylglucosamine metabolic process (GO:0006047)2.68407843
127negative regulation of mRNA processing (GO:0050686)2.61273077
128negative regulation of fatty acid biosynthetic process (GO:0045717)2.60299901
129regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.59997606
130ovulation from ovarian follicle (GO:0001542)2.56893972
131L-serine metabolic process (GO:0006563)2.56832104
132cholesterol biosynthetic process (GO:0006695)2.53885376
133L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.53185054
134purine nucleobase biosynthetic process (GO:0009113)2.52241241
135CENP-A containing nucleosome assembly (GO:0034080)2.51039839
136DNA synthesis involved in DNA repair (GO:0000731)2.45819282
137telomere maintenance via telomerase (GO:0007004)2.45174132
138S-adenosylmethionine metabolic process (GO:0046500)2.43770904
139nuclear pore organization (GO:0006999)2.42069923
140tetrahydrofolate metabolic process (GO:0046653)2.41749321
141sodium-independent organic anion transport (GO:0043252)2.41044178
142heme transport (GO:0015886)2.40716179
143plasma lipoprotein particle organization (GO:0071827)2.37319685
144formation of translation preinitiation complex (GO:0001731)2.36890463
145sister chromatid cohesion (GO:0007062)2.35626748
146ketone body metabolic process (GO:1902224)2.34513787
147regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.32420407
148organelle disassembly (GO:1903008)2.32285829
149drug metabolic process (GO:0017144)2.31667129
150negative regulation of mRNA metabolic process (GO:1903312)2.31611161

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse8.04513440
2EGR1_23403033_ChIP-Seq_LIVER_Mouse6.10579426
3RXR_22158963_ChIP-Seq_LIVER_Mouse5.71273726
4PPARA_22158963_ChIP-Seq_LIVER_Mouse4.76277915
5LXR_22158963_ChIP-Seq_LIVER_Mouse4.49371302
6E2F7_22180533_ChIP-Seq_HELA_Human4.39102493
7CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.26623219
8FOXO1_23066095_ChIP-Seq_LIVER_Mouse3.55415539
9GABP_17652178_ChIP-ChIP_JURKAT_Human3.50863776
10CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.17156930
11TRIM28_21343339_ChIP-Seq_HEK293_Human3.05981064
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.92743731
13NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.88570619
14PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.84560434
15E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.67232495
16MYC_18555785_ChIP-Seq_MESCs_Mouse2.63222528
17EST1_17652178_ChIP-ChIP_JURKAT_Human2.55296164
18E2F4_17652178_ChIP-ChIP_JURKAT_Human2.52807844
19ELK1_19687146_ChIP-ChIP_HELA_Human2.51161334
20PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.46129242
21TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.45130387
22AR_21909140_ChIP-Seq_LNCAP_Human2.27208273
23PRDM5_23873026_ChIP-Seq_MEFs_Mouse2.24793730
24JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.24115453
25PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.23437514
26KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.19928857
27SALL1_21062744_ChIP-ChIP_HESCs_Human2.12033565
28HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.03508769
29PADI4_21655091_ChIP-ChIP_MCF-7_Human2.01749165
30* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.00274827
31CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.94861552
32* ETS1_20019798_ChIP-Seq_JURKAT_Human1.93810974
33* DCP1A_22483619_ChIP-Seq_HELA_Human1.87262173
34FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.84338398
35MYC_19030024_ChIP-ChIP_MESCs_Mouse1.83391955
36VDR_23849224_ChIP-Seq_CD4+_Human1.82118780
37SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.80842388
38MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.79575717
39HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.78036018
40MYCN_18555785_ChIP-Seq_MESCs_Mouse1.77527267
41CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.73190457
42STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.73015462
43* NOTCH1_21737748_ChIP-Seq_TLL_Human1.70254888
44NFE2_27457419_Chip-Seq_LIVER_Mouse1.68323622
45NELFA_20434984_ChIP-Seq_ESCs_Mouse1.67960035
46E2F1_21310950_ChIP-Seq_MCF-7_Human1.64601159
47SUZ12_27294783_Chip-Seq_NPCs_Mouse1.64411065
48FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.64316740
49PCGF2_27294783_Chip-Seq_ESCs_Mouse1.62787465
50E2F1_18555785_ChIP-Seq_MESCs_Mouse1.58903109
51NRF2_20460467_ChIP-Seq_MEFs_Mouse1.58449119
52NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.58449119
53ZNF274_21170338_ChIP-Seq_K562_Hela1.58146721
54EZH2_27294783_Chip-Seq_NPCs_Mouse1.56504143
55FLI1_27457419_Chip-Seq_LIVER_Mouse1.54837811
56CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.53569901
57ELF1_17652178_ChIP-ChIP_JURKAT_Human1.52326763
58RARG_19884340_ChIP-ChIP_MEFs_Mouse1.51723639
59IRF8_22096565_ChIP-ChIP_GC-B_Human1.51391521
60KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.51052709
61PCGF2_27294783_Chip-Seq_NPCs_Mouse1.49849259
62FOXP3_21729870_ChIP-Seq_TREG_Human1.49588091
63GABP_19822575_ChIP-Seq_HepG2_Human1.47990092
64TAF15_26573619_Chip-Seq_HEK293_Human1.47933078
65HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.47897330
66EWS_26573619_Chip-Seq_HEK293_Human1.47006398
67MYC_19079543_ChIP-ChIP_MESCs_Mouse1.45378807
68TTF2_22483619_ChIP-Seq_HELA_Human1.44638299
69YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.41975542
70HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.40846743
71TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.39856401
72MYC_18358816_ChIP-ChIP_MESCs_Mouse1.39799690
73CRX_20693478_ChIP-Seq_RETINA_Mouse1.37553020
74FUS_26573619_Chip-Seq_HEK293_Human1.33049250
75POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.32202953
76SALL4_18804426_ChIP-ChIP_XEN_Mouse1.29036228
77TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.28501507
78FOXM1_23109430_ChIP-Seq_U2OS_Human1.28206127
79BP1_19119308_ChIP-ChIP_Hs578T_Human1.26886909
80HTT_18923047_ChIP-ChIP_STHdh_Human1.26777440
81CJUN_26792858_Chip-Seq_BT549_Human1.26169336
82GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.22763864
83CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.22169272
84* PIAS1_25552417_ChIP-Seq_VCAP_Human1.21041050
85POU3F2_20337985_ChIP-ChIP_501MEL_Human1.20902640
86ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.20548433
87TFEB_21752829_ChIP-Seq_HELA_Human1.19004901
88RBPJ_22232070_ChIP-Seq_NCS_Mouse1.18022284
89SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.16006345
90OCT4_21477851_ChIP-Seq_ESCs_Mouse1.15370721
91ZFX_18555785_ChIP-Seq_MESCs_Mouse1.14972140
92EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.13683164
93CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.13515055
94GATA1_22025678_ChIP-Seq_K562_Human1.12145964
95TP53_18474530_ChIP-ChIP_U2OS_Human1.11963010
96SOX17_20123909_ChIP-Seq_XEN_Mouse1.11410446
97ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.06622405
98HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.05872362
99EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.05260404
100TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.05253815
101POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.05050134
102* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.04583610
103MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.03433350
104CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.03265332
105Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.01520801
106AR_20517297_ChIP-Seq_VCAP_Human1.00775400
107P53_22387025_ChIP-Seq_ESCs_Mouse1.00245542
108ZFP57_27257070_Chip-Seq_ESCs_Mouse1.00146120
109PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.99818167
110MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.99455315
111STAT3_18555785_Chip-Seq_ESCs_Mouse0.98838637
112GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98688837
113RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.98480997
114RUNX1_27457419_Chip-Seq_LIVER_Mouse0.98204899
115HOXB4_20404135_ChIP-ChIP_EML_Mouse0.97746064
116ZFX_18555785_Chip-Seq_ESCs_Mouse0.97660366
117NANOG_16153702_ChIP-ChIP_HESCs_Human0.97180646
118ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.97105978
119MYC_18940864_ChIP-ChIP_HL60_Human0.97064399
120PU1_27457419_Chip-Seq_LIVER_Mouse0.96566421
121NMYC_18555785_Chip-Seq_ESCs_Mouse0.94607345
122EGR1_19374776_ChIP-ChIP_THP-1_Human0.93953465
123PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.93892185
124SUZ12_18555785_Chip-Seq_ESCs_Mouse0.93888262
125OCT4_18555785_Chip-Seq_ESCs_Mouse0.93337541
126SMAD1_18555785_Chip-Seq_ESCs_Mouse0.93052543
127AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.92834450
128IGF1R_20145208_ChIP-Seq_DFB_Human0.92753779
129GATA4_25053715_ChIP-Seq_YYC3_Human0.92625551
130SOX2_20726797_ChIP-Seq_SW620_Human0.92434715
131MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.92401288
132GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.92305097
133SRF_21415370_ChIP-Seq_HL-1_Mouse0.92117866
134E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.91846253
135ESRRB_18555785_Chip-Seq_ESCs_Mouse0.90106249
136KAP1_22055183_ChIP-Seq_ESCs_Mouse0.89751628
137ELK1_22589737_ChIP-Seq_MCF10A_Human0.89172980
138CDX2_22108803_ChIP-Seq_LS180_Human0.88898830
139TP63_19390658_ChIP-ChIP_HaCaT_Human0.87914980
140SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.87573420
141CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.87013317
142ESR1_21235772_ChIP-Seq_MCF-7_Human0.86909486
143NANOG_18555785_Chip-Seq_ESCs_Mouse0.86862330
144HNF4A_19822575_ChIP-Seq_HepG2_Human0.85638056
145UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.85321678
146EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.85255406
147STAT1_17558387_ChIP-Seq_HELA_Human0.84480602
148BCAT_22108803_ChIP-Seq_LS180_Human0.84056242
149ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.83910226
150EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.82543765
151E2F1_18555785_Chip-Seq_ESCs_Mouse0.82503032
152TP53_22573176_ChIP-Seq_HFKS_Human0.82261382
153SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.81992993
154THAP11_20581084_ChIP-Seq_MESCs_Mouse0.81900443
155EP300_21415370_ChIP-Seq_HL-1_Mouse0.81620758
156IRF1_19129219_ChIP-ChIP_H3396_Human0.81595666
157P300_18555785_Chip-Seq_ESCs_Mouse0.81135026
158RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.80768747
159STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.80503841
160TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.79418699
161WT1_19549856_ChIP-ChIP_CCG9911_Human0.78764289
162TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.78173972
163CDX2_19796622_ChIP-Seq_MESCs_Mouse0.77687869
164AUTS2_25519132_ChIP-Seq_293T-REX_Human0.76751981
165SOX2_18555785_Chip-Seq_ESCs_Mouse0.76383437
166P300_19829295_ChIP-Seq_ESCs_Human0.75713330
167HNFA_21074721_ChIP-Seq_CACO-2_Human0.75213172
168CLOCK_20551151_ChIP-Seq_293T_Human0.74371705
169FOXM1_26456572_ChIP-Seq_MCF-7_Human0.74338899
170TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.74247910

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system5.97030192
2MP0005360_urolithiasis4.93615503
3MP0005085_abnormal_gallbladder_physiolo4.92079780
4MP0005365_abnormal_bile_salt4.26306933
5MP0003950_abnormal_plasma_membrane3.75148357
6MP0008875_abnormal_xenobiotic_pharmacok3.70668578
7MP0003806_abnormal_nucleotide_metabolis3.43783321
8MP0008438_abnormal_cutaneous_collagen3.32905821
9MP0003252_abnormal_bile_duct3.25384353
10MP0003195_calcinosis3.23694316
11MP0003693_abnormal_embryo_hatching2.87006304
12MP0005503_abnormal_tendon_morphology2.63438317
13MP0002254_reproductive_system_inflammat2.14767538
14MP0004957_abnormal_blastocyst_morpholog2.14607906
15MP0010329_abnormal_lipoprotein_level2.11644353
16MP0008058_abnormal_DNA_repair2.09713087
17MP0005083_abnormal_biliary_tract2.02477684
18MP0003868_abnormal_feces_composition1.99569595
19MP0010094_abnormal_chromosome_stability1.99303083
20MP0008057_abnormal_DNA_replication1.96246628
21MP0009697_abnormal_copulation1.93935309
22MP0008877_abnormal_DNA_methylation1.93337818
23MP0005332_abnormal_amino_acid1.89941807
24MP0003111_abnormal_nucleus_morphology1.87467968
25MP0009379_abnormal_foot_pigmentation1.86283738
26MP0001666_abnormal_nutrient_absorption1.84694485
27MP0002138_abnormal_hepatobiliary_system1.83418953
28MP0004019_abnormal_vitamin_homeostasis1.76047305
29MP0005275_abnormal_skin_tensile1.73977731
30MP0000566_synostosis1.61172621
31MP0005084_abnormal_gallbladder_morpholo1.60431565
32MP0005220_abnormal_exocrine_pancreas1.60302091
33MP0003724_increased_susceptibility_to1.57591489
34MP0001764_abnormal_homeostasis1.57368090
35MP0008932_abnormal_embryonic_tissue1.53328069
36MP0010368_abnormal_lymphatic_system1.52396652
37MP0003941_abnormal_skin_development1.52077143
38MP0003123_paternal_imprinting1.50111868
39MP0003186_abnormal_redox_activity1.49156188
40MP0010030_abnormal_orbit_morphology1.44267775
41MP0003077_abnormal_cell_cycle1.40958199
42MP0009384_cardiac_valve_regurgitation1.39296153
43MP0006035_abnormal_mitochondrial_morpho1.38880257
44MP0005451_abnormal_body_composition1.37983510
45MP0006036_abnormal_mitochondrial_physio1.36042734
46MP0001542_abnormal_bone_strength1.35551124
47MP0000609_abnormal_liver_physiology1.33420942
48MP0003890_abnormal_embryonic-extraembry1.31035530
49MP0002060_abnormal_skin_morphology1.29734583
50MP0002933_joint_inflammation1.29553674
51MP0005319_abnormal_enzyme/_coenzyme1.26488380
52MP0003011_delayed_dark_adaptation1.24856676
53MP0002132_abnormal_respiratory_system1.24524818
54MP0003279_aneurysm1.20949545
55MP0002118_abnormal_lipid_homeostasis1.19740234
56MP0009840_abnormal_foam_cell1.19575856
57MP0009250_abnormal_appendicular_skeleto1.18947107
58MP0009764_decreased_sensitivity_to1.15389518
59MP0005551_abnormal_eye_electrophysiolog1.14893120
60MP0008007_abnormal_cellular_replicative1.11278088
61MP0001697_abnormal_embryo_size1.09235763
62MP0005508_abnormal_skeleton_morphology1.08604395
63MP0003705_abnormal_hypodermis_morpholog1.07347142
64MP0001881_abnormal_mammary_gland1.07125656
65MP0001293_anophthalmia1.00835465
66MP0001299_abnormal_eye_distance/1.00392655
67MP0001958_emphysema1.00337159
68MP0002697_abnormal_eye_size1.00278334
69MP0005266_abnormal_metabolism1.00052960
70MP0009703_decreased_birth_body0.99841493
71MP0000358_abnormal_cell_content/0.99390316
72MP0005257_abnormal_intraocular_pressure0.98465732
73MP0003937_abnormal_limbs/digits/tail_de0.97727872
74MP0005248_abnormal_Harderian_gland0.96514228
75MP0000163_abnormal_cartilage_morphology0.95807752
76MP0005670_abnormal_white_adipose0.94576161
77MP0003121_genomic_imprinting0.93269249
78MP0004381_abnormal_hair_follicle0.91976413
79MP0005408_hypopigmentation0.91814631
80MP0006292_abnormal_olfactory_placode0.91223289
81MP0002249_abnormal_larynx_morphology0.91188745
82MP0009643_abnormal_urine_homeostasis0.89832318
83MP0001730_embryonic_growth_arrest0.89821619
84MP0003567_abnormal_fetal_cardiomyocyte0.89685085
85MP0005390_skeleton_phenotype0.88734820
86MP0005647_abnormal_sex_gland0.87455512
87MP0001243_abnormal_dermal_layer0.87156804
88MP0001188_hyperpigmentation0.87054910
89MP0003136_yellow_coat_color0.86955052
90MP0001324_abnormal_eye_pigmentation0.86593727
91MP0002233_abnormal_nose_morphology0.86251521
92MP0000767_abnormal_smooth_muscle0.86227452
93MP0000350_abnormal_cell_proliferation0.86170074
94MP0006054_spinal_hemorrhage0.86138202
95MP0004782_abnormal_surfactant_physiolog0.85723075
96MP0001915_intracranial_hemorrhage0.85518968
97MP0002282_abnormal_trachea_morphology0.84900434
98MP0009763_increased_sensitivity_to0.82272213
99MP0004134_abnormal_chest_morphology0.81739975
100MP0003656_abnormal_erythrocyte_physiolo0.81551281
101MP0002084_abnormal_developmental_patter0.79975725
102MP0002115_abnormal_skeleton_extremities0.79875970
103MP0004272_abnormal_basement_membrane0.79779888
104MP0002877_abnormal_melanocyte_morpholog0.79356882
105MP0002090_abnormal_vision0.79326422
106MP0002896_abnormal_bone_mineralization0.78726920
107MP0004215_abnormal_myocardial_fiber0.78067796
108MP0005197_abnormal_uvea_morphology0.77148132
109MP0001286_abnormal_eye_development0.77075156
110MP0003828_pulmonary_edema0.76716984
111MP0001929_abnormal_gametogenesis0.76389578
112MP0008469_abnormal_protein_level0.75783736
113MP0003786_premature_aging0.75783161
114MP0001533_abnormal_skeleton_physiology0.75771954
115MP0002085_abnormal_embryonic_tissue0.73642990
116MP0003221_abnormal_cardiomyocyte_apopto0.72692006
117MP0003315_abnormal_perineum_morphology0.72605957
118MP0005379_endocrine/exocrine_gland_phen0.72147714
119MP0000598_abnormal_liver_morphology0.71884646
120MP0005395_other_phenotype0.71162364
121MP0004233_abnormal_muscle_weight0.70948704
122MP0001727_abnormal_embryo_implantation0.70501251
123MP0005376_homeostasis/metabolism_phenot0.70401872
124MP0002332_abnormal_exercise_endurance0.68965222
125MP0002108_abnormal_muscle_morphology0.68690188
126MP0002210_abnormal_sex_determination0.68505342
127MP0000653_abnormal_sex_gland0.68068260
128MP0005380_embryogenesis_phenotype0.67960041
129MP0001672_abnormal_embryogenesis/_devel0.67960041
130MP0005584_abnormal_enzyme/coenzyme_acti0.67448561
131MP0003436_decreased_susceptibility_to0.66649341
132MP0003718_maternal_effect0.66601760
133MP0003755_abnormal_palate_morphology0.66417525
134MP0002295_abnormal_pulmonary_circulatio0.66313571
135MP0009053_abnormal_anal_canal0.65426359
136MP0005334_abnormal_fat_pad0.65411086
137MP0004197_abnormal_fetal_growth/weight/0.65039291
138MP0000762_abnormal_tongue_morphology0.64956522
139MP0006072_abnormal_retinal_apoptosis0.64822746
140MP0002088_abnormal_embryonic_growth/wei0.64727440
141MP0003984_embryonic_growth_retardation0.64637450
142MP0002009_preneoplasia0.63485032
143MP0001919_abnormal_reproductive_system0.62909174
144MP0000049_abnormal_middle_ear0.62600301
145MP0005636_abnormal_mineral_homeostasis0.62431568
146MP0003795_abnormal_bone_structure0.62044640
147MP0002837_dystrophic_cardiac_calcinosis0.62008062
148MP0002998_abnormal_bone_remodeling0.61662447
149MP0009642_abnormal_blood_homeostasis0.60976167
150MP0002168_other_aberrant_phenotype0.60600087
151MP0010386_abnormal_urinary_bladder0.60531520
152MP0005164_abnormal_response_to0.59494357
153MP0001853_heart_inflammation0.58092161
154MP0000613_abnormal_salivary_gland0.57872705
155MP0005595_abnormal_vascular_smooth0.57409278
156MP0002113_abnormal_skeleton_development0.56937682
157MP0002876_abnormal_thyroid_physiology0.55314907
158MP0002938_white_spotting0.54430611
159MP0003191_abnormal_cellular_cholesterol0.53780331

Predicted human phenotypes

RankGene SetZ-score
1Prolonged partial thromboplastin time (HP:0003645)5.54324163
2Intrahepatic cholestasis (HP:0001406)4.94647590
3Abnormality of pyruvate family amino acid metabolism (HP:0010915)4.78817460
4Abnormality of alanine metabolism (HP:0010916)4.78817460
5Hyperalaninemia (HP:0003348)4.78817460
6Abnormality of aromatic amino acid family metabolism (HP:0004338)4.61761723
7Abnormality of monocarboxylic acid metabolism (HP:0010996)4.52958620
8Deep venous thrombosis (HP:0002625)4.32543712
9Hypobetalipoproteinemia (HP:0003563)4.15949205
10Xanthomatosis (HP:0000991)4.08568808
11Joint hemorrhage (HP:0005261)3.97835498
12Premature rupture of membranes (HP:0001788)3.55478171
13Abnormality of methionine metabolism (HP:0010901)3.54055226
14Renal cortical cysts (HP:0000803)3.49862996
15Complement deficiency (HP:0004431)3.41013000
16Hypolipoproteinemia (HP:0010981)3.40823778
17Increased serum pyruvate (HP:0003542)3.36774382
18Abnormality of pyrimidine metabolism (HP:0004353)3.33667531
19Hyperlipoproteinemia (HP:0010980)3.29274156
20Conjugated hyperbilirubinemia (HP:0002908)3.22150692
21Hypoalphalipoproteinemia (HP:0003233)3.21762629
22Abnormality of aspartate family amino acid metabolism (HP:0010899)3.20520717
23Fat malabsorption (HP:0002630)3.18960063
24Myocardial infarction (HP:0001658)3.18381954
25Abnormality of glutamine family amino acid metabolism (HP:0010902)3.14342524
26Hypoglycemic coma (HP:0001325)3.12268700
27Abnormality of the intrinsic pathway (HP:0010989)3.11988502
28Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.07662985
29Acute encephalopathy (HP:0006846)3.07398419
30Abnormality of the common coagulation pathway (HP:0010990)3.07098871
31Abnormality of glycolysis (HP:0004366)2.98172540
32Acute necrotizing encephalopathy (HP:0006965)2.94416229
33Metaphyseal dysplasia (HP:0100255)2.87407383
34Abnormality of complement system (HP:0005339)2.85541302
35Hyperglycinemia (HP:0002154)2.81240000
36Hyperammonemia (HP:0001987)2.77670530
37Increased serum ferritin (HP:0003281)2.75151579
38Abnormality of sulfur amino acid metabolism (HP:0004339)2.70578586
39Hyperglycinuria (HP:0003108)2.67704374
40Neonatal short-limb short stature (HP:0008921)2.63008039
41Abnormality of fatty-acid metabolism (HP:0004359)2.62305390
42Enlarged kidneys (HP:0000105)2.62205034
43Steatorrhea (HP:0002570)2.58952842
44Abnormality of serine family amino acid metabolism (HP:0010894)2.58771401
45Abnormality of glycine metabolism (HP:0010895)2.58771401
46Protrusio acetabuli (HP:0003179)2.57977496
47Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.57975472
48Epidermoid cyst (HP:0200040)2.56345605
49Vitreoretinal degeneration (HP:0000655)2.56333360
50Abnormality of serum amino acid levels (HP:0003112)2.53819560
51Increased CSF lactate (HP:0002490)2.52545805
52Ketosis (HP:0001946)2.51262536
53Progressive macrocephaly (HP:0004481)2.46961491
54Abnormal mitochondria in muscle tissue (HP:0008316)2.44697496
55Cardiovascular calcification (HP:0011915)2.40916182
56Hypophosphatemic rickets (HP:0004912)2.36533340
57Vascular calcification (HP:0004934)2.35679941
58Glomerulonephritis (HP:0000099)2.35595581
59Abnormality of dicarboxylic acid metabolism (HP:0010995)2.34019391
60Dicarboxylic aciduria (HP:0003215)2.34019391
61Abnormal delivery (HP:0001787)2.32409830
62Nausea (HP:0002018)2.30966269
63Spontaneous abortion (HP:0005268)2.30643664
64Patchy hypopigmentation of hair (HP:0011365)2.30415816
65Increased serum lactate (HP:0002151)2.28674115
66Abnormality of the labia minora (HP:0012880)2.28334150
67Generalized aminoaciduria (HP:0002909)2.27739884
68Hyperbilirubinemia (HP:0002904)2.26942800
69Abnormality of iron homeostasis (HP:0011031)2.22191916
70Abnormality of vitamin metabolism (HP:0100508)2.21883262
71Arthropathy (HP:0003040)2.21465300
72Cerebral edema (HP:0002181)2.21062070
73Systemic lupus erythematosus (HP:0002725)2.18948887
74Hepatocellular carcinoma (HP:0001402)2.18650331
75Mitral stenosis (HP:0001718)2.17985743
76Epiphyseal dysplasia (HP:0002656)2.15145695
77Chronic hepatic failure (HP:0100626)2.14200534
78Menorrhagia (HP:0000132)2.12972054
79Pulmonary artery stenosis (HP:0004415)2.11927758
80Chromsome breakage (HP:0040012)2.11707411
81Hydroxyprolinuria (HP:0003080)2.09630471
82Abnormality of proline metabolism (HP:0010907)2.09630471
83Reduced antithrombin III activity (HP:0001976)2.08832714
84Hypercholesterolemia (HP:0003124)2.07823599
85Mitochondrial inheritance (HP:0001427)2.06970340
86Bifid tongue (HP:0010297)2.05541716
87Hyperglycemia (HP:0003074)2.05473637
88Hypoglycemic seizures (HP:0002173)2.03702070
89Delayed gross motor development (HP:0002194)2.02876936
90Abnormality of transition element cation homeostasis (HP:0011030)2.02876771
91Beaking of vertebral bodies (HP:0004568)2.02612338
92Abnormality of nucleobase metabolism (HP:0010932)2.02100651
93Cupped ribs (HP:0000887)2.01943089
94Submucous cleft hard palate (HP:0000176)1.98928940
95Gingival bleeding (HP:0000225)1.98581828
96Posterior subcapsular cataract (HP:0007787)1.97898237
97Lethargy (HP:0001254)1.97756553
98Microvesicular hepatic steatosis (HP:0001414)1.95086051
99Metabolic acidosis (HP:0001942)1.93360742
100Abnormality of the renal cortex (HP:0011035)1.93120553
101Irregular epiphyses (HP:0010582)1.93006400
102Abnormal tarsal ossification (HP:0008369)1.92924784
103Biconcave vertebral bodies (HP:0004586)1.91668378
104Abnormality of chromosome stability (HP:0003220)1.89417326
105Ketoacidosis (HP:0001993)1.89222151
106Abnormal cartilage morphology (HP:0002763)1.88628043
107CNS demyelination (HP:0007305)1.88118823
108Respiratory distress (HP:0002098)1.88087379
109Cerebral palsy (HP:0100021)1.86480166
110Aplasia/Hypoplasia of the sacrum (HP:0008517)1.85866690
111Hyperinsulinemic hypoglycemia (HP:0000825)1.85772941
1123-Methylglutaconic aciduria (HP:0003535)1.84769964
113Abnormality of urine glucose concentration (HP:0011016)1.84434375
114Glycosuria (HP:0003076)1.84434375
115Pancreatitis (HP:0001733)1.83867802
116Redundant skin (HP:0001582)1.82769136
117Nuclear cataract (HP:0100018)1.82667061
118Vertebral compression fractures (HP:0002953)1.82617686
119Methylmalonic acidemia (HP:0002912)1.82163448
120Skin nodule (HP:0200036)1.81395050
121Symptomatic seizures (HP:0011145)1.80063206
122Lactic acidosis (HP:0003128)1.79605628
123Chromosomal breakage induced by crosslinking agents (HP:0003221)1.79058476
124Multiple enchondromatosis (HP:0005701)1.79036571
125Megaloblastic anemia (HP:0001889)1.78966991
126Increased hepatocellular lipid droplets (HP:0006565)1.78788092
127Flat capital femoral epiphysis (HP:0003370)1.77638739
128Peritonitis (HP:0002586)1.77530165
129Hepatic necrosis (HP:0002605)1.76549733
130Papillary thyroid carcinoma (HP:0002895)1.76547982
131Distal lower limb muscle weakness (HP:0009053)1.76480783
132Hypochromic microcytic anemia (HP:0004840)1.76369727
133Delayed CNS myelination (HP:0002188)1.76368975
134Protuberant abdomen (HP:0001538)1.75268808
135Soft skin (HP:0000977)1.75045113
136Proximal tubulopathy (HP:0000114)1.73911292
137Poor head control (HP:0002421)1.72593417
138Sensorimotor neuropathy (HP:0007141)1.71787447
139Abnormality of the pons (HP:0007361)1.71561998
140Hypoplastic ischia (HP:0003175)1.68097350
141Rickets (HP:0002748)1.67946568
142Large for gestational age (HP:0001520)1.67435161
143Hyperphosphaturia (HP:0003109)1.66786854
144Hepatocellular necrosis (HP:0001404)1.66754077
145Pancreatic fibrosis (HP:0100732)1.66381448
146Meckel diverticulum (HP:0002245)1.65505407
147Type I transferrin isoform profile (HP:0003642)1.65272221
148White forelock (HP:0002211)1.64690710
149Secondary amenorrhea (HP:0000869)1.62851231
150Blue sclerae (HP:0000592)1.62104786
151Neoplasm of the adrenal gland (HP:0100631)1.60351830
152Limb-girdle muscle atrophy (HP:0003797)1.60112000
153Type II lissencephaly (HP:0007260)1.59811785
154Renal Fanconi syndrome (HP:0001994)1.58633213
155Abnormality of vitamin B metabolism (HP:0004340)1.58563603
156Methylmalonic aciduria (HP:0012120)1.56607920
157Small hand (HP:0200055)1.56273173
158Meningioma (HP:0002858)1.54972056
159Abnormal hair whorl (HP:0010721)1.54760377
160Pancreatic cysts (HP:0001737)1.54669930
161Abnormality of midbrain morphology (HP:0002418)1.54079280

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK24.36300197
2IRAK33.79350155
3BCKDK3.13894198
4PNCK3.13058424
5INSRR3.10398542
6MAP3K122.99253589
7CDC72.74254062
8ZAK2.38318076
9STK38L2.37607374
10PBK2.35825494
11LATS12.35295811
12WNK32.34776402
13NEK92.32979010
14NME22.31380221
15MKNK22.30203173
16NUAK12.26410752
17TTK2.12501684
18SIK12.04496591
19EIF2AK11.93063531
20MAP3K141.92277626
21NEK11.91871363
22BRD41.90989063
23ERN11.89798912
24TRIM281.88482403
25CASK1.87903990
26BLK1.83552153
27TNIK1.81650948
28MAP3K31.76845985
29WEE11.73632843
30STK161.67864958
31PLK31.67638405
32TSSK61.66978623
33ERBB41.62218213
34MST41.57429153
35EIF2AK21.56430569
36PIK3CG1.52782945
37NME11.51987294
38EIF2AK31.50812640
39MKNK11.49826500
40STK241.48318826
41TAOK31.47315570
42ERBB31.33768541
43AKT31.32804307
44FRK1.32522743
45PLK11.30030112
46MAPK151.29584200
47PIK3CA1.28963824
48TLK11.28722198
49IRAK41.28660904
50PIM21.21913899
51YES11.21548064
52SCYL21.13521542
53STK31.11671005
54EPHA31.06325698
55NLK1.03319701
56TAF11.03229762
57IRAK11.03073498
58EPHA21.02339822
59AKT21.01443512
60GRK11.00484063
61LATS20.96827095
62TXK0.92390184
63MAP3K90.91598517
64CSNK1G10.90201868
65DDR20.89507822
66CHEK20.89218509
67RPS6KA40.88898547
68IKBKB0.86586045
69BUB10.86515390
70EPHB20.86430054
71ADRBK20.85769860
72FLT30.85021367
73OBSCN0.84981522
74ACVR1B0.84209327
75TEC0.84136034
76CSNK1E0.83447673
77BMPR1B0.82275589
78MST1R0.81324876
79BRSK20.79479152
80TGFBR20.78884999
81PLK20.78587213
82FGFR40.75316195
83MAPK110.72027886
84CSNK2A20.71450330
85CHEK10.71427855
86BCR0.70985693
87MYLK0.70173108
88BMPR20.70028078
89ATR0.69106536
90MOS0.68937253
91TIE10.68483432
92TRPM70.67138248
93MAP3K50.66805351
94ALK0.66172877
95AURKB0.65836550
96PAK30.65820214
97CSNK1G20.64308494
98NEK60.63639655
99CHUK0.63424448
100STK40.63341524
101ATM0.63318088
102MUSK0.62955969
103ABL20.61424695
104WNK40.60799544
105BRAF0.59638291
106PRKAA20.59405936
107PINK10.57678662
108GRK70.57563640
109DYRK30.54749434
110TYK20.54486610
111IRAK20.53813607
112PKN10.52899328
113KSR10.52828014
114CSNK1G30.51245185
115MAPK40.50662410
116PRKCE0.50224294
117TAOK20.50082801
118CDK90.48870448
119PLK40.48635380
120VRK10.47571864
121MAPKAPK50.47434827
122PRKACB0.47163695
123GSK3A0.46455089
124DMPK0.46136479
125KDR0.45522592
126FGFR10.45415960
127MAP3K40.44457080
128ROCK10.43273803
129SGK20.43082684
130SRPK10.42843218
131CDK10.42361925
132MET0.41808147
133CSK0.39597138
134MAPK70.39392724
135OXSR10.39089329
136ERBB20.38746759
137CDK30.38178257
138MARK30.36997006
139TNK20.36955899
140PIM10.36893920
141CSNK1A10.35357171
142PRKCG0.35342969
143RPS6KA50.35220822
144LYN0.35140054
145IKBKE0.34319996
146CSNK2A10.34271376
147CDK80.34140573
148FER0.34115947
149CDK70.33895935
150PRKCQ0.33639758
151BRSK10.33043228
152CDK60.32604712
153RPS6KA60.32552921
154PAK20.32478161
155CDK20.32305289
156STK390.31562965
157PRKG20.30949244
158MAPK140.30484179

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001203.57608331
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.31198801
3Pentose and glucuronate interconversions_Homo sapiens_hsa000402.79994228
4Complement and coagulation cascades_Homo sapiens_hsa046102.74262451
5Tryptophan metabolism_Homo sapiens_hsa003802.47141461
6Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.28056678
7Fatty acid degradation_Homo sapiens_hsa000712.26489691
8Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.19490224
9Steroid hormone biosynthesis_Homo sapiens_hsa001402.19151763
10Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.17621859
11Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.13839116
12Peroxisome_Homo sapiens_hsa041462.13297568
13Retinol metabolism_Homo sapiens_hsa008302.13259645
14Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.06310692
15Chemical carcinogenesis_Homo sapiens_hsa052042.05968116
16Drug metabolism - other enzymes_Homo sapiens_hsa009832.05864624
17Pantothenate and CoA biosynthesis_Homo sapiens_hsa007702.05494619
18Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.04465962
19Arginine biosynthesis_Homo sapiens_hsa002201.94064632
20Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.93483646
21Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.91008571
22Starch and sucrose metabolism_Homo sapiens_hsa005001.86189430
23Staphylococcus aureus infection_Homo sapiens_hsa051501.83635773
24Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.82389042
25Caffeine metabolism_Homo sapiens_hsa002321.82059923
26Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.82020523
27Maturity onset diabetes of the young_Homo sapiens_hsa049501.74756541
28Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.70436711
29Mismatch repair_Homo sapiens_hsa034301.63152453
30Histidine metabolism_Homo sapiens_hsa003401.62821209
31beta-Alanine metabolism_Homo sapiens_hsa004101.62569178
32Butanoate metabolism_Homo sapiens_hsa006501.61384041
33Protein export_Homo sapiens_hsa030601.60052164
34Propanoate metabolism_Homo sapiens_hsa006401.59599487
35PPAR signaling pathway_Homo sapiens_hsa033201.58119886
36Proteasome_Homo sapiens_hsa030501.56845717
37One carbon pool by folate_Homo sapiens_hsa006701.55476307
38Sulfur metabolism_Homo sapiens_hsa009201.52775497
39Folate biosynthesis_Homo sapiens_hsa007901.46854750
40Selenocompound metabolism_Homo sapiens_hsa004501.46489942
41Fatty acid elongation_Homo sapiens_hsa000621.46150722
42DNA replication_Homo sapiens_hsa030301.45745618
43Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.41805056
44Fatty acid metabolism_Homo sapiens_hsa012121.40861264
45Basal transcription factors_Homo sapiens_hsa030221.39058686
46RNA transport_Homo sapiens_hsa030131.36797978
47Non-homologous end-joining_Homo sapiens_hsa034501.30055014
48Nitrogen metabolism_Homo sapiens_hsa009101.28264209
49Phenylalanine metabolism_Homo sapiens_hsa003601.27841501
50Spliceosome_Homo sapiens_hsa030401.27074278
51Arginine and proline metabolism_Homo sapiens_hsa003301.25674707
52Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.24764200
53Nucleotide excision repair_Homo sapiens_hsa034201.20739439
54Tyrosine metabolism_Homo sapiens_hsa003501.19357795
55ABC transporters_Homo sapiens_hsa020101.14563021
56Huntingtons disease_Homo sapiens_hsa050161.10162738
57Steroid biosynthesis_Homo sapiens_hsa001001.08984257
58Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.05381058
59Vitamin digestion and absorption_Homo sapiens_hsa049771.00723194
60Sulfur relay system_Homo sapiens_hsa041220.96170633
61RNA degradation_Homo sapiens_hsa030180.96100786
62Fat digestion and absorption_Homo sapiens_hsa049750.95879083
63Phototransduction_Homo sapiens_hsa047440.91187237
64Vitamin B6 metabolism_Homo sapiens_hsa007500.88851636
65Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.88582743
66Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.88377076
67Glutathione metabolism_Homo sapiens_hsa004800.86677910
68Cysteine and methionine metabolism_Homo sapiens_hsa002700.83821708
69Circadian rhythm_Homo sapiens_hsa047100.83591768
70Cyanoamino acid metabolism_Homo sapiens_hsa004600.83529685
71Pyruvate metabolism_Homo sapiens_hsa006200.82200539
722-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.80163597
73Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.79748831
74Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.79655757
75Lysine degradation_Homo sapiens_hsa003100.74596440
76Carbon metabolism_Homo sapiens_hsa012000.73246677
77Biosynthesis of amino acids_Homo sapiens_hsa012300.71020662
78Base excision repair_Homo sapiens_hsa034100.70736214
79Purine metabolism_Homo sapiens_hsa002300.70152625
80Cell cycle_Homo sapiens_hsa041100.69604794
81Metabolic pathways_Homo sapiens_hsa011000.67976052
82Mineral absorption_Homo sapiens_hsa049780.67804095
83Alzheimers disease_Homo sapiens_hsa050100.65075615
84Ribosome_Homo sapiens_hsa030100.64042284
85Galactose metabolism_Homo sapiens_hsa000520.58392466
86Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.58193597
87Bile secretion_Homo sapiens_hsa049760.57769123
88ECM-receptor interaction_Homo sapiens_hsa045120.55294131
89mRNA surveillance pathway_Homo sapiens_hsa030150.55046226
90Protein digestion and absorption_Homo sapiens_hsa049740.54867976
91Arachidonic acid metabolism_Homo sapiens_hsa005900.54137214
92Malaria_Homo sapiens_hsa051440.52550182
93TGF-beta signaling pathway_Homo sapiens_hsa043500.48324215
94Other glycan degradation_Homo sapiens_hsa005110.46744328
95Linoleic acid metabolism_Homo sapiens_hsa005910.44424814
96Pyrimidine metabolism_Homo sapiens_hsa002400.42563734
97p53 signaling pathway_Homo sapiens_hsa041150.41807520
98Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.38186361
99Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.37567761
100Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.37324952
101alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.37180485
102Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.34659662
103Oxidative phosphorylation_Homo sapiens_hsa001900.33653040
104Legionellosis_Homo sapiens_hsa051340.30269691
105Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.29562262
106Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.27803820
107Pentose phosphate pathway_Homo sapiens_hsa000300.27035815
108Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.26984298
109Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.26519387
110Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.24122188
111NF-kappa B signaling pathway_Homo sapiens_hsa040640.23135808
112Glycerolipid metabolism_Homo sapiens_hsa005610.22733102
113Parkinsons disease_Homo sapiens_hsa050120.21644446
114Sphingolipid metabolism_Homo sapiens_hsa006000.19998420
115Glycosaminoglycan degradation_Homo sapiens_hsa005310.19767915
116Prion diseases_Homo sapiens_hsa050200.18653040
117Graft-versus-host disease_Homo sapiens_hsa053320.17982636
118Hematopoietic cell lineage_Homo sapiens_hsa046400.17291605
119Fanconi anemia pathway_Homo sapiens_hsa034600.14592302
120Homologous recombination_Homo sapiens_hsa034400.13211528
121RNA polymerase_Homo sapiens_hsa030200.13012578
122Intestinal immune network for IgA production_Homo sapiens_hsa046720.13002268
123Fatty acid biosynthesis_Homo sapiens_hsa000610.10878800
124Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.09590130
125Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.08622284

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