DNAJA4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)9.68459028
2epithelial cilium movement (GO:0003351)8.87057662
3axoneme assembly (GO:0035082)7.44877018
4left/right pattern formation (GO:0060972)6.05831156
5regulation of cilium movement (GO:0003352)5.96555522
6left/right axis specification (GO:0070986)5.12991537
7negative regulation of potassium ion transmembrane transporter activity (GO:1901017)5.06245893
8negative regulation of potassium ion transmembrane transport (GO:1901380)4.93656262
9ventricular system development (GO:0021591)4.79052362
10plasma membrane repair (GO:0001778)4.77949999
11sarcomere organization (GO:0045214)4.77870516
12microtubule bundle formation (GO:0001578)4.77538931
13one-carbon compound transport (GO:0019755)4.55895015
14positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)4.48868242
15vitamin transmembrane transport (GO:0035461)4.39590362
16regulation of microtubule-based movement (GO:0060632)4.21846211
17cardiac myofibril assembly (GO:0055003)4.21044372
18diterpenoid biosynthetic process (GO:0016102)4.19201033
19sperm capacitation (GO:0048240)4.18728765
20primary alcohol catabolic process (GO:0034310)4.13052079
21ethanol metabolic process (GO:0006067)4.12833809
22sarcoplasmic reticulum calcium ion transport (GO:0070296)4.12469737
23regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)4.10883984
24regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO4.06693245
25regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)4.06097653
26actin-myosin filament sliding (GO:0033275)4.03782891
27muscle filament sliding (GO:0030049)4.03782891
28myofibril assembly (GO:0030239)4.00655895
29negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.89636982
30cilium organization (GO:0044782)3.86466362
31detection of calcium ion (GO:0005513)3.82266691
32cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.81640720
33regulation of skeletal muscle contraction (GO:0014819)3.80619294
34regulation of interleukin-5 production (GO:0032674)3.76428703
35cardiac muscle contraction (GO:0060048)3.75550735
36cilium assembly (GO:0042384)3.73769370
37regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.72939172
38regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.70993561
39regulation of membrane repolarization (GO:0060306)3.65217204
40* negative regulation of inclusion body assembly (GO:0090084)3.63481304
41intraciliary transport (GO:0042073)3.60688328
42regulation of germinal center formation (GO:0002634)3.53661697
43cytoplasmic microtubule organization (GO:0031122)3.49233975
44cell communication involved in cardiac conduction (GO:0086065)3.46301714
45gas transport (GO:0015669)3.42110075
46membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.40091734
47relaxation of cardiac muscle (GO:0055119)3.39096226
48regulation of interleukin-13 production (GO:0032656)3.37662285
49response to xenobiotic stimulus (GO:0009410)3.36574815
50centriole assembly (GO:0098534)3.36573599
51ventricular cardiac muscle cell action potential (GO:0086005)3.36434394
52actin-mediated cell contraction (GO:0070252)3.34881091
53regulation of cell communication by electrical coupling (GO:0010649)3.34425840
54cellular component assembly involved in morphogenesis (GO:0010927)3.32555524
55lung epithelium development (GO:0060428)3.30922818
56microtubule-based movement (GO:0007018)3.30563790
57regulation of actin filament-based movement (GO:1903115)3.28589482
58cell communication by electrical coupling (GO:0010644)3.27534191
59striated muscle contraction (GO:0006941)3.26890157
60positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.26670649
61negative regulation of B cell mediated immunity (GO:0002713)3.24750426
62negative regulation of immunoglobulin mediated immune response (GO:0002890)3.24750426
63potassium ion import (GO:0010107)3.22275910
64pyrimidine-containing compound transmembrane transport (GO:0072531)3.20469399
65tolerance induction (GO:0002507)3.19706764
66tricarboxylic acid cycle (GO:0006099)3.16729541
67carnitine shuttle (GO:0006853)3.16138230
68ethanol oxidation (GO:0006069)3.15899139
69piRNA metabolic process (GO:0034587)3.15699954
70actomyosin structure organization (GO:0031032)3.15631991
71activation of protein kinase A activity (GO:0034199)3.11742825
72regulation of calcium ion transmembrane transport (GO:1903169)3.11425482
73regulation of calcium ion transmembrane transporter activity (GO:1901019)3.11425482
74glomerular epithelial cell development (GO:0072310)3.06188414
75iron ion import (GO:0097286)3.05339593
76regulation of relaxation of muscle (GO:1901077)3.03677795
77negative regulation of potassium ion transport (GO:0043267)3.00872654
78histone H3-K9 demethylation (GO:0033169)2.98791350
79protein localization to cilium (GO:0061512)2.97453029
80regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.95669001
81positive regulation of cation channel activity (GO:2001259)2.94147389
82creatine metabolic process (GO:0006600)2.93962956
83heart trabecula formation (GO:0060347)2.93523909
84membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.92685136
85cell projection assembly (GO:0030031)2.89635668
86cardiac muscle cell development (GO:0055013)2.88698149
87male meiosis I (GO:0007141)2.87290760
88regulation of striated muscle contraction (GO:0006942)2.87191440
89skeletal muscle adaptation (GO:0043501)2.83485013
90carnitine transmembrane transport (GO:1902603)2.80922285
91regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.80815360
92regulation of response to osmotic stress (GO:0047484)2.79337263
93positive regulation of potassium ion transport (GO:0043268)2.79323433
94negative regulation of humoral immune response (GO:0002921)2.79051546
95sperm motility (GO:0030317)2.79026013
96protein targeting to Golgi (GO:0000042)2.76072066
97synapsis (GO:0007129)2.75540029
98cardiac conduction (GO:0061337)2.73933429
99regulation of ARF protein signal transduction (GO:0032012)2.73204317
100positive regulation of tolerance induction (GO:0002645)2.72430901
101macroautophagy (GO:0016236)2.71965892
102skeletal muscle contraction (GO:0003009)2.68494222
103membrane repolarization during action potential (GO:0086011)2.68002757
104membrane depolarization during action potential (GO:0086010)2.67856623
105amino-acid betaine transport (GO:0015838)2.66986381
106carnitine transport (GO:0015879)2.66986381
107cardiac cell development (GO:0055006)2.66861588
108fatty acid transmembrane transport (GO:1902001)2.66390780
109regulation of heart rate by cardiac conduction (GO:0086091)2.65302971
110positive regulation of potassium ion transmembrane transport (GO:1901381)2.64913188
111cardiac muscle hypertrophy (GO:0003300)2.63054286
112regulation of acyl-CoA biosynthetic process (GO:0050812)2.62288297
113microtubule polymerization or depolymerization (GO:0031109)2.62254818
114actin filament-based movement (GO:0030048)2.62230515
115phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.61357500
116cardiac muscle cell action potential involved in contraction (GO:0086002)2.61227574
117bundle of His cell to Purkinje myocyte communication (GO:0086069)2.61151461
118DNA methylation involved in gamete generation (GO:0043046)2.60010516
119relaxation of muscle (GO:0090075)2.59661563
120positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.59376650
121striated muscle hypertrophy (GO:0014897)2.58438009
122sodium ion homeostasis (GO:0055078)2.57030863
123cytoskeletal anchoring at plasma membrane (GO:0007016)2.56856260
124regulation of potassium ion transmembrane transport (GO:1901379)2.56688125
125cerebellar granule cell differentiation (GO:0021707)2.56316243
126cardiac muscle cell action potential (GO:0086001)2.55724691
127negative regulation of T cell differentiation in thymus (GO:0033085)2.55225011
128neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.55173217
129regulation of cation channel activity (GO:2001257)2.55145515
130membrane repolarization (GO:0086009)2.54594379
131negative regulation of calcium ion transmembrane transporter activity (GO:1901020)2.54447128
132negative regulation of calcium ion transmembrane transport (GO:1903170)2.54447128
133apical protein localization (GO:0045176)2.54399783
134establishment of protein localization to Golgi (GO:0072600)2.53599661
135regulation of p38MAPK cascade (GO:1900744)2.53137824
136synaptic vesicle maturation (GO:0016188)2.53103346
137* regulation of inclusion body assembly (GO:0090083)2.52884112
138regulation of the force of heart contraction (GO:0002026)2.52078888
139sodium ion export (GO:0071436)2.51534088
140striated muscle atrophy (GO:0014891)2.51135965
141positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.49780956
142multicellular organismal water homeostasis (GO:0050891)2.49231666
143phosphatidylcholine biosynthetic process (GO:0006656)2.48596257
144retrograde transport, vesicle recycling within Golgi (GO:0000301)2.47706276
145muscle contraction (GO:0006936)2.47637269
146negative regulation of cytosolic calcium ion concentration (GO:0051481)2.46574329
147regulation of cardiac muscle cell contraction (GO:0086004)2.45919811
148cilium morphogenesis (GO:0060271)2.45705151
149regulation of cardiac muscle contraction (GO:0055117)2.45362178
150negative regulation of protein localization to cell surface (GO:2000009)2.43636893
151regulation of potassium ion transmembrane transporter activity (GO:1901016)2.43538433
152retinoic acid metabolic process (GO:0042573)2.42942264
153quaternary ammonium group transport (GO:0015697)2.42938048
154histone H3-K36 demethylation (GO:0070544)2.42487524
155potassium ion homeostasis (GO:0055075)2.42263789
156mitochondrion degradation (GO:0000422)2.40827059
157regulation of heart rate (GO:0002027)2.40650311
158cellular potassium ion homeostasis (GO:0030007)2.39211339
159regulation of synapse structural plasticity (GO:0051823)2.37957829
160oxygen transport (GO:0015671)2.37872211
161regulation of heart contraction (GO:0008016)2.36786081
162negative regulation of ion transmembrane transporter activity (GO:0032413)2.36623411
163adult heart development (GO:0007512)2.36475353
164positive regulation of ion transmembrane transporter activity (GO:0032414)2.35370253
165COPI coating of Golgi vesicle (GO:0048205)2.33581130
166Golgi transport vesicle coating (GO:0048200)2.33581130
167regulation of sodium ion transmembrane transport (GO:1902305)2.33236004
168cardiac muscle tissue morphogenesis (GO:0055008)2.32569506
169regulation of microtubule depolymerization (GO:0031114)2.30751863
170carnitine metabolic process (GO:0009437)2.29534448
171establishment of apical/basal cell polarity (GO:0035089)2.25833741
172axonemal dynein complex assembly (GO:0070286)15.0093263
173cilium or flagellum-dependent cell motility (GO:0001539)13.4005511
174cilium movement (GO:0003341)10.8851527
175motile cilium assembly (GO:0044458)10.8110168

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.21164342
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.64365000
3EP300_21415370_ChIP-Seq_HL-1_Mouse2.25215304
4FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.96412749
5DROSHA_22980978_ChIP-Seq_HELA_Human1.90737270
6TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.85630628
7PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.80309813
8RARB_27405468_Chip-Seq_BRAIN_Mouse1.76387802
9STAT6_21828071_ChIP-Seq_BEAS2B_Human1.76040468
10TBX20_22080862_ChIP-Seq_HEART_Mouse1.75400163
11TBX20_22328084_ChIP-Seq_HEART_Mouse1.75400163
12* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.75272258
13* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.74419449
14SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.69850968
15CDX2_19796622_ChIP-Seq_MESCs_Mouse1.69357477
16ESR1_20079471_ChIP-ChIP_T-47D_Human1.66984691
17* SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.64546966
18* SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.56568852
19EZH2_27294783_Chip-Seq_ESCs_Mouse1.55013531
20ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.53488217
21SMC4_20622854_ChIP-Seq_HELA_Human1.53214342
22* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.49472003
23TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.47339904
24REST_21632747_ChIP-Seq_MESCs_Mouse1.41482322
25TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.40437189
26* RNF2_18974828_ChIP-Seq_MESCs_Mouse1.39747173
27* EZH2_18974828_ChIP-Seq_MESCs_Mouse1.39747173
28ESR2_21235772_ChIP-Seq_MCF-7_Human1.38022542
29BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.38022280
30ZNF263_19887448_ChIP-Seq_K562_Human1.37212648
31CTNNB1_20460455_ChIP-Seq_HCT116_Human1.36019121
32SOX2_27498859_Chip-Seq_STOMACH_Mouse1.33396573
33ZNF217_24962896_ChIP-Seq_MCF-7_Human1.31326579
34FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.29899757
35AR_21572438_ChIP-Seq_LNCaP_Human1.29166743
36THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.26503524
37NR3C1_23031785_ChIP-Seq_PC12_Mouse1.26302700
38* SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.25775991
39EZH2_27304074_Chip-Seq_ESCs_Mouse1.24278198
40RNF2_27304074_Chip-Seq_ESCs_Mouse1.23529012
41ZNF274_21170338_ChIP-Seq_K562_Hela1.22893206
42* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.21738345
43ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.21572976
44* JARID2_20064375_ChIP-Seq_MESCs_Mouse1.21145378
45* JARID2_20075857_ChIP-Seq_MESCs_Mouse1.20519099
46KDM2B_26808549_Chip-Seq_K562_Human1.18772906
47REST_18959480_ChIP-ChIP_MESCs_Mouse1.18178924
48EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.17887473
49WT1_25993318_ChIP-Seq_PODOCYTE_Human1.17453964
50FOXM1_26456572_ChIP-Seq_MCF-7_Human1.15640640
51GATA1_19941826_ChIP-Seq_K562_Human1.14534061
52GATA2_19941826_ChIP-Seq_K562_Human1.14151076
53TP63_23658742_ChIP-Seq_EP156T_Human1.13553786
54* SMAD4_21799915_ChIP-Seq_A2780_Human1.13196671
55GATA1_22025678_ChIP-Seq_K562_Human1.12342563
56AHR_22903824_ChIP-Seq_MCF-7_Human1.11712959
57PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.11692088
58TP63_22573176_ChIP-Seq_HFKS_Human1.11504475
59KLF5_25053715_ChIP-Seq_YYC3_Human1.10617401
60GBX2_23144817_ChIP-Seq_PC3_Human1.08776441
61ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.06108257
62TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.05715513
63SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05618113
64ARNT_22903824_ChIP-Seq_MCF-7_Human1.05337322
65SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.04730541
66NR3C1_21868756_ChIP-Seq_MCF10A_Human1.04065793
67EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.03865069
68* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.03554826
69KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.03399366
70* CTCF_27219007_Chip-Seq_Bcells_Human1.03126740
71TRIM28_21343339_ChIP-Seq_HEK293_Human1.02577503
72RAD21_21589869_ChIP-Seq_MESCs_Mouse1.02245199
73SOX2_21211035_ChIP-Seq_LN229_Gbm1.01853732
74CREB1_26743006_Chip-Seq_LNCaP_Human1.00156162
75STAT1_20625510_ChIP-Seq_HELA_Human0.99119420
76EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.97701235
77SMRT_27268052_Chip-Seq_Bcells_Human0.97664096
78BCAT_22108803_ChIP-Seq_LS180_Human0.96948118
79SMAD3_21741376_ChIP-Seq_HESCs_Human0.96034337
80PIAS1_25552417_ChIP-Seq_VCAP_Human0.95492601
81SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.95472060
82ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.95360664
83FOXA1_25552417_ChIP-Seq_VCAP_Human0.94660087
84SMAD4_21741376_ChIP-Seq_HESCs_Human0.94243507
85GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92304455
86EED_16625203_ChIP-ChIP_MESCs_Mouse0.91281526
87RUNX1_27514584_Chip-Seq_MCF-7_Human0.90997088
88ESR1_21235772_ChIP-Seq_MCF-7_Human0.90925872
89TOP2B_26459242_ChIP-Seq_MCF-7_Human0.90820703
90NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.89691662
91FOXA2_19822575_ChIP-Seq_HepG2_Human0.89578516
92* GATA1_19941827_ChIP-Seq_MEL_Mouse0.88935538
93PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.88744345
94ETV1_20927104_ChIP-Seq_GIST48_Human0.88516604
95RACK7_27058665_Chip-Seq_MCF-7_Human0.88381748
96P68_20966046_ChIP-Seq_HELA_Human0.88194936
97PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.88122802
98PHF8_20622853_ChIP-Seq_HELA_Human0.88118450
99FOXO3_23340844_ChIP-Seq_DLD1_Human0.87876490
100MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.87873837
101HNFA_21074721_ChIP-Seq_CACO-2_Human0.87242625
102AR_19668381_ChIP-Seq_PC3_Human0.86822211
103SMAD3_21741376_ChIP-Seq_ESCs_Human0.86671523
104SOX9_24532713_ChIP-Seq_HFSC_Mouse0.86612273
105CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.86412182
106CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.86294191
107MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.86184164
108TBL1_22424771_ChIP-Seq_293T_Human0.86091169
109GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85779388
110WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.85456163
111* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.85366330
112FOXH1_21741376_ChIP-Seq_ESCs_Human0.85119343
113DNAJC2_21179169_ChIP-ChIP_NT2_Human0.84642595
114STAT3_23295773_ChIP-Seq_U87_Human0.84271046
115TDRD3_21172665_ChIP-Seq_MCF-7_Human0.84159551
116VDR_22108803_ChIP-Seq_LS180_Human0.83259089
117RING1B_27294783_Chip-Seq_ESCs_Mouse0.83012657
118KLF4_19829295_ChIP-Seq_ESCs_Human0.82987035
119SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.82855975
120NFIB_24661679_ChIP-Seq_LUNG_Mouse0.82829162
121* P63_26484246_Chip-Seq_KERATINOCYTES_Human0.82412425
122RARG_19884340_ChIP-ChIP_MEFs_Mouse0.82387152
123MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.82254280
124ERG_21242973_ChIP-ChIP_JURKAT_Human0.82236708
125AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.82165552
126TET1_21490601_ChIP-Seq_MESCs_Mouse0.81969946
127GATA2_21666600_ChIP-Seq_HMVEC_Human0.81964253
128PPAR_26484153_Chip-Seq_NCI-H1993_Human0.81902693
129KDM2B_26808549_Chip-Seq_SUP-B15_Human0.81778995
130MYC_27129775_Chip-Seq_CORNEA_Mouse0.81752437
131TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.81646501
132SMAD3_21741376_ChIP-Seq_EPCs_Human0.81423973
133GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81382262
134SMAD4_21741376_ChIP-Seq_EPCs_Human0.81352617
135LXR_22292898_ChIP-Seq_THP-1_Human0.81196444
136TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.81151609
137AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.81071295
138YAP1_20516196_ChIP-Seq_MESCs_Mouse0.81032018
139TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.80412693
140CTBP2_25329375_ChIP-Seq_LNCAP_Human0.80175237
141RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.79964836
142PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.79532196
143TP53_18474530_ChIP-ChIP_U2OS_Human0.79342327
144EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.78558634
145NFYB_21822215_ChIP-Seq_K562_Human0.78442082
146CBX2_22325352_ChIP-Seq_293T-Rex_Human0.77859470

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis5.51958897
2MP0000751_myopathy4.03282451
3MP0003646_muscle_fatigue3.77216167
4MP0004084_abnormal_cardiac_muscle3.68924282
5MP0002653_abnormal_ependyma_morphology3.66919034
6MP0004036_abnormal_muscle_relaxation3.47131836
7MP0008875_abnormal_xenobiotic_pharmacok3.36361311
8MP0000749_muscle_degeneration3.27423932
9MP0004215_abnormal_myocardial_fiber3.11735043
10MP0004145_abnormal_muscle_electrophysio3.11192933
11MP0002132_abnormal_respiratory_system2.98163591
12MP0002909_abnormal_adrenal_gland2.61645490
13MP0005330_cardiomyopathy2.44011746
14MP0004087_abnormal_muscle_fiber2.41351782
15MP0004130_abnormal_muscle_cell2.38776968
16MP0000013_abnormal_adipose_tissue2.33961656
17MP0005620_abnormal_muscle_contractility2.30083282
18MP0004043_abnormal_pH_regulation2.22809575
19MP0004859_abnormal_synaptic_plasticity2.21259682
20MP0000747_muscle_weakness2.17425173
21MP0002972_abnormal_cardiac_muscle2.17340024
22MP0004270_analgesia2.12379768
23MP0009780_abnormal_chondrocyte_physiolo2.05941613
24MP0002106_abnormal_muscle_physiology2.01538780
25MP0000383_abnormal_hair_follicle1.98366390
26MP0005083_abnormal_biliary_tract1.91280898
27MP0002277_abnormal_respiratory_mucosa1.91274828
28MP0005410_abnormal_fertilization1.90988303
29MP0004484_altered_response_of1.90411266
30MP0002269_muscular_atrophy1.89914861
31MP0003137_abnormal_impulse_conducting1.89615688
32MP0002877_abnormal_melanocyte_morpholog1.87483979
33MP0010678_abnormal_skin_adnexa1.79537119
34MP0002234_abnormal_pharynx_morphology1.78652281
35MP0004085_abnormal_heartbeat1.78117683
36MP0000759_abnormal_skeletal_muscle1.76521641
37MP0008775_abnormal_heart_ventricle1.74243995
38MP0008961_abnormal_basal_metabolism1.71524223
39MP0000750_abnormal_muscle_regeneration1.69052060
40MP0005369_muscle_phenotype1.68352308
41MP0010630_abnormal_cardiac_muscle1.54199615
42MP0005385_cardiovascular_system_phenoty1.53751699
43MP0001544_abnormal_cardiovascular_syste1.53751699
44MP0006138_congestive_heart_failure1.51870511
45MP0002160_abnormal_reproductive_system1.47807160
46MP0000678_abnormal_parathyroid_gland1.45463957
47MP0000003_abnormal_adipose_tissue1.44109675
48MP0004233_abnormal_muscle_weight1.42938220
49MP0003635_abnormal_synaptic_transmissio1.41818113
50MP0004510_myositis1.40321752
51MP0002822_catalepsy1.38111046
52MP0005666_abnormal_adipose_tissue1.33199250
53MP0005423_abnormal_somatic_nervous1.31901228
54MP0005375_adipose_tissue_phenotype1.29802097
55MP0005409_darkened_coat_color1.28725717
56MP0003698_abnormal_male_reproductive1.26644952
57MP0002168_other_aberrant_phenotype1.25032226
58MP0005670_abnormal_white_adipose1.21627705
59MP0001765_abnormal_ion_homeostasis1.21119257
60MP0001929_abnormal_gametogenesis1.20390387
61MP0003303_peritoneal_inflammation1.20356153
62MP0004185_abnormal_adipocyte_glucose1.19209666
63MP0003329_amyloid_beta_deposits1.17508326
64MP0005310_abnormal_salivary_gland1.16447578
65MP0005636_abnormal_mineral_homeostasis1.16257835
66MP0004019_abnormal_vitamin_homeostasis1.11893828
67MP0006036_abnormal_mitochondrial_physio1.10502265
68MP0004147_increased_porphyrin_level1.10467135
69MP0002735_abnormal_chemical_nociception1.10428776
70MP0002638_abnormal_pupillary_reflex1.10402315
71MP0002693_abnormal_pancreas_physiology1.09638046
72MP0005623_abnormal_meninges_morphology1.09167282
73MP0005377_hearing/vestibular/ear_phenot1.07143347
74MP0003878_abnormal_ear_physiology1.07143347
75MP0002078_abnormal_glucose_homeostasis1.04936405
76MP0008569_lethality_at_weaning1.03375581
77MP0003221_abnormal_cardiomyocyte_apopto1.01355751
78MP0005535_abnormal_body_temperature1.00388442
79MP0001346_abnormal_lacrimal_gland1.00210959
80MP0002272_abnormal_nervous_system0.99454834
81MP0003045_fibrosis0.99097665
82MP0003828_pulmonary_edema0.98668160
83MP0003283_abnormal_digestive_organ0.98128188
84MP0009745_abnormal_behavioral_response0.97392733
85MP0004133_heterotaxia0.97304962
86MP0005646_abnormal_pituitary_gland0.95885889
87MP0001664_abnormal_digestion0.95878888
88MP0010386_abnormal_urinary_bladder0.95344561
89MP0002249_abnormal_larynx_morphology0.95268329
90MP0002063_abnormal_learning/memory/cond0.95219506
91MP0008877_abnormal_DNA_methylation0.95215927
92MP0001944_abnormal_pancreas_morphology0.93415713
93MP0002064_seizures0.93104815
94MP0002734_abnormal_mechanical_nocicepti0.92338931
95MP0010234_abnormal_vibrissa_follicle0.91509771
96MP0000230_abnormal_systemic_arterial0.89665479
97MP0002067_abnormal_sensory_capabilities0.89615191
98MP0002108_abnormal_muscle_morphology0.89140517
99MP0004742_abnormal_vestibular_system0.88957684
100MP0003075_altered_response_to0.88809601
101MP0002229_neurodegeneration0.88606800
102MP0001299_abnormal_eye_distance/0.87261899
103MP0005166_decreased_susceptibility_to0.85740013
104MP0003950_abnormal_plasma_membrane0.83646080
105MP0003453_abnormal_keratinocyte_physiol0.82831170
106MP0001501_abnormal_sleep_pattern0.82688713
107MP0000566_synostosis0.82259099
108MP0008789_abnormal_olfactory_epithelium0.78978612
109MP0002127_abnormal_cardiovascular_syste0.78648053
110MP0003633_abnormal_nervous_system0.78620806
111MP0001440_abnormal_grooming_behavior0.78568951
112MP0009046_muscle_twitch0.77305383
113MP0005165_increased_susceptibility_to0.76893956
114MP0005187_abnormal_penis_morphology0.75516563
115MP0002971_abnormal_brown_adipose0.75434311
116MP0004858_abnormal_nervous_system0.75276502
117MP0002332_abnormal_exercise_endurance0.74691461
118MP0010368_abnormal_lymphatic_system0.74349667
119MP0003880_abnormal_central_pattern0.73922931
120MP0004924_abnormal_behavior0.72614630
121MP0005386_behavior/neurological_phenoty0.72614630
122MP0003195_calcinosis0.71991496
123MP0003690_abnormal_glial_cell0.71586515
124MP0003656_abnormal_erythrocyte_physiolo0.71293354
125MP0004885_abnormal_endolymph0.68342191
126MP0002066_abnormal_motor_capabilities/c0.68195852
127MP0009278_abnormal_bone_marrow0.67331678
128MP0003300_gastrointestinal_ulcer0.65913744
129MP0002572_abnormal_emotion/affect_behav0.65876964
130MP0001984_abnormal_olfaction0.64255146
131MP0002896_abnormal_bone_mineralization0.62930840
132MP0001502_abnormal_circadian_rhythm0.62756727
133MP0000266_abnormal_heart_morphology0.62286780
134MP0001970_abnormal_pain_threshold0.61755387
135MP0005167_abnormal_blood-brain_barrier0.61461963
136MP0003879_abnormal_hair_cell0.60563573
137MP0002295_abnormal_pulmonary_circulatio0.59114630
138MP0001486_abnormal_startle_reflex0.59047952
139MP0006072_abnormal_retinal_apoptosis0.58561467

Predicted human phenotypes

RankGene SetZ-score
1Bronchiectasis (HP:0002110)6.50626993
2Nasal polyposis (HP:0100582)6.34431364
3Exercise-induced myalgia (HP:0003738)5.78388298
4Abnormality of the nasal mucosa (HP:0000433)5.40670288
5Sudden death (HP:0001699)5.34678271
6Calf muscle hypertrophy (HP:0008981)4.98978075
7Hyporeflexia of lower limbs (HP:0002600)4.90619624
8Muscle hypertrophy of the lower extremities (HP:0008968)4.78846789
9Exercise-induced muscle cramps (HP:0003710)4.78401860
10Muscle fiber splitting (HP:0003555)4.56957342
11Bundle branch block (HP:0011710)4.13319628
12Myoglobinuria (HP:0002913)4.10279514
13Ventricular tachycardia (HP:0004756)3.94990254
14Abnormality of the calf musculature (HP:0001430)3.93874105
15Infertility (HP:0000789)3.93836907
16Recurrent sinusitis (HP:0011108)3.82128064
17Difficulty running (HP:0009046)3.81967691
18Bronchitis (HP:0012387)3.70537494
19Atrial fibrillation (HP:0005110)3.66708575
20Prolonged QT interval (HP:0001657)3.63357309
21Muscle fiber inclusion bodies (HP:0100299)3.63170935
22Subaortic stenosis (HP:0001682)3.54432540
23Abnormality of the left ventricular outflow tract (HP:0011103)3.54432540
24EMG: myopathic abnormalities (HP:0003458)3.53512870
25Ventricular fibrillation (HP:0001663)3.51131440
26Male infertility (HP:0003251)3.50482714
27Primary atrial arrhythmia (HP:0001692)3.44507424
28Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)3.43661591
29Syncope (HP:0001279)3.39921024
30Recurrent otitis media (HP:0000403)3.32643235
31Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.32282692
32Chronic sinusitis (HP:0011109)3.32077108
33Asymmetric septal hypertrophy (HP:0001670)3.27064546
34Supraventricular tachycardia (HP:0004755)3.23236890
35Chronic bronchitis (HP:0004469)3.21671842
36Hyperinsulinemic hypoglycemia (HP:0000825)3.20171355
37Supraventricular arrhythmia (HP:0005115)3.17128210
38Type 1 muscle fiber predominance (HP:0003803)3.12322605
39Right ventricular cardiomyopathy (HP:0011663)3.11466096
40Heart block (HP:0012722)3.05411337
41Ketoacidosis (HP:0001993)3.01078569
42Hyperkalemia (HP:0002153)2.94901163
43Increased variability in muscle fiber diameter (HP:0003557)2.92894394
44Myotonia (HP:0002486)2.92538975
45Abnormal atrioventricular conduction (HP:0005150)2.92529194
46Hyperactive renin-angiotensin system (HP:0000841)2.90268785
47Nemaline bodies (HP:0003798)2.89728521
48Difficulty climbing stairs (HP:0003551)2.87153248
49Ventricular arrhythmia (HP:0004308)2.86879768
50Increased connective tissue (HP:0009025)2.85856113
51Atelectasis (HP:0100750)2.82909834
52Atrioventricular block (HP:0001678)2.82167195
53Lipoatrophy (HP:0100578)2.78039597
54Occipital encephalocele (HP:0002085)2.77832880
55Abnormality of skeletal muscle fiber size (HP:0012084)2.71501098
56Palpitations (HP:0001962)2.67687727
57Absent/shortened dynein arms (HP:0200106)2.65464159
58Dynein arm defect of respiratory motile cilia (HP:0012255)2.65464159
59Dilated cardiomyopathy (HP:0001644)2.63504956
60Abnormal EKG (HP:0003115)2.62791061
61Large for gestational age (HP:0001520)2.61817847
62Chronic otitis media (HP:0000389)2.59030907
63Hypoglycemic coma (HP:0001325)2.58126473
64Abnormal respiratory motile cilium physiology (HP:0012261)2.58103536
65Insulin-resistant diabetes mellitus (HP:0000831)2.53867308
66Hyperglycemia (HP:0003074)2.46062229
67Central scotoma (HP:0000603)2.45874137
68Muscle stiffness (HP:0003552)2.43554608
69Rhabdomyolysis (HP:0003201)2.38596474
70Myopathic facies (HP:0002058)2.38508251
71EMG: neuropathic changes (HP:0003445)2.38185791
72Mildly elevated creatine phosphokinase (HP:0008180)2.31292396
73Distal arthrogryposis (HP:0005684)2.26927128
74Neck muscle weakness (HP:0000467)2.24090136
75Tubulointerstitial nephritis (HP:0001970)2.24028219
76Pheochromocytoma (HP:0002666)2.23116251
77True hermaphroditism (HP:0010459)2.20302738
78Pancreatic fibrosis (HP:0100732)2.19556840
79Decreased circulating renin level (HP:0003351)2.19429952
80Rhinitis (HP:0012384)2.18096419
81Round ear (HP:0100830)2.17611639
82Left ventricular hypertrophy (HP:0001712)2.17283095
83Bell-shaped thorax (HP:0001591)2.16410422
84Diaphragmatic weakness (HP:0009113)2.15559706
85Gowers sign (HP:0003391)2.14096628
86Testicular atrophy (HP:0000029)2.11259124
87Nephronophthisis (HP:0000090)2.09045771
88Abnormal ciliary motility (HP:0012262)2.08775329
89Fetal akinesia sequence (HP:0001989)2.06605382
90Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.06326810
91Rapidly progressive (HP:0003678)2.05867577
92Cystic liver disease (HP:0006706)2.03865388
93Areflexia of lower limbs (HP:0002522)2.03134971
94Visual hallucinations (HP:0002367)1.98644862
95Scapular winging (HP:0003691)1.95025505
96Hypoglycemic seizures (HP:0002173)1.94835467
97Ketosis (HP:0001946)1.93782375
98Dysmetric saccades (HP:0000641)1.93639401
99Pancreatic islet-cell hyperplasia (HP:0004510)1.93256724
100Foot dorsiflexor weakness (HP:0009027)1.91172018
101Limb-girdle muscle atrophy (HP:0003797)1.90244949
102Obstructive sleep apnea (HP:0002870)1.89628428
103Abnormality of the foot musculature (HP:0001436)1.87070566
104Facial diplegia (HP:0001349)1.86478932
105Proximal amyotrophy (HP:0007126)1.86419718
106Abnormality of potassium homeostasis (HP:0011042)1.85229882
107Fatigable weakness (HP:0003473)1.81884608
108Abnormality of the neuromuscular junction (HP:0003398)1.81884608
109Frequent falls (HP:0002359)1.81660268
110Neuroendocrine neoplasm (HP:0100634)1.80962558
111Muscular dystrophy (HP:0003560)1.77532159
112Hypokalemia (HP:0002900)1.75902624
113Recurrent bronchitis (HP:0002837)1.75500735
114Distal lower limb amyotrophy (HP:0008944)1.75125077
115Lower limb amyotrophy (HP:0007210)1.74109238
116Depression (HP:0000716)1.72984807
117Rimmed vacuoles (HP:0003805)1.72123125
118Abnormal respiratory motile cilium morphology (HP:0005938)1.71087399
119Abnormal respiratory epithelium morphology (HP:0012253)1.71087399
120Gout (HP:0001997)1.69015770
121Distal lower limb muscle weakness (HP:0009053)1.68814295
122Cholelithiasis (HP:0001081)1.68492893
123Renal salt wasting (HP:0000127)1.68207443
124Abnormality of the renal medulla (HP:0100957)1.67400236
125Atonic seizures (HP:0010819)1.66964044
126Abnormality of midbrain morphology (HP:0002418)1.66578991
127Molar tooth sign on MRI (HP:0002419)1.66578991
128Hypoplastic ischia (HP:0003175)1.65734169
129Abnormality of chloride homeostasis (HP:0011422)1.61452621
130Chronic hepatic failure (HP:0100626)1.58834609
131Nonprogressive disorder (HP:0003680)1.56293355
132Hyperaldosteronism (HP:0000859)1.55724046
133Ankle clonus (HP:0011448)1.54370376
134Hyponatremia (HP:0002902)1.53380947
135Postaxial foot polydactyly (HP:0001830)1.52944706
136Congenital hepatic fibrosis (HP:0002612)1.52139612
137Pancreatic cysts (HP:0001737)1.49061256
138Abnormality of renin-angiotensin system (HP:0000847)1.43200728
139Abnormality of permanent molar morphology (HP:0011071)1.40810706
140Abnormality of the dental root (HP:0006486)1.40810706
141Taurodontia (HP:0000679)1.40810706
142Postural instability (HP:0002172)1.40125060
143Tubular atrophy (HP:0000092)1.39764219
144Lip pit (HP:0100267)1.37779556
145Cone-rod dystrophy (HP:0000548)1.37153089
146Gait imbalance (HP:0002141)1.35578698
147Absent speech (HP:0001344)1.34756920
148Focal motor seizures (HP:0011153)1.32682744
149Dysdiadochokinesis (HP:0002075)1.30627007
150Abnormality of sodium homeostasis (HP:0010931)1.30276336
151Medial flaring of the eyebrow (HP:0010747)1.30237451
152Popliteal pterygium (HP:0009756)1.29673295
153Anencephaly (HP:0002323)1.28022566
154Hypokalemic alkalosis (HP:0001949)1.27849483
155Abnormality of the dental pulp (HP:0006479)1.27592517
156Abnormality of molar morphology (HP:0011070)1.27340777
157Abnormality of molar (HP:0011077)1.27340777
158Hand muscle atrophy (HP:0009130)1.26726430
159Febrile seizures (HP:0002373)1.26117406
160Male pseudohermaphroditism (HP:0000037)1.25326449
161Congenital primary aphakia (HP:0007707)1.22744357

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN3.40535011
2PDK33.38893596
3PDK43.38893596
4MST43.22670634
5OBSCN3.15005803
6EPHA22.93594461
7PHKG12.88599406
8PHKG22.88599406
9PRKD32.86467729
10LMTK22.56393992
11DMPK2.54863101
12TRIB32.51815100
13INSRR2.12434921
14MAPK152.07585364
15PDK22.06306299
16PINK12.03874304
17WNK41.93641237
18TSSK61.64865036
19MUSK1.53302053
20MAP3K21.50915863
21KSR21.39825431
22NTRK31.36860807
23TIE11.34562504
24RIPK41.34453474
25TRPM71.30936575
26PAK31.28195475
27STK391.26434105
28NEK61.25986523
29STK381.25310617
30EPHA41.24770626
31PKN21.23652269
32MAP3K11.23176658
33MAP3K91.23067329
34MYLK1.19226305
35EEF2K1.15281016
36MAPKAPK51.14940898
37MAP3K131.14920251
38WNK11.14771121
39PRKCH1.11910142
40MAP3K41.08967505
41CAMK1G1.08588339
42PRPF4B1.07438170
43MAP3K71.06846781
44TAOK11.06512101
45TAOK31.05556275
46PRKD11.02741483
47PAK61.01947273
48RIPK11.00205557
49HIPK20.97359305
50MAPKAPK30.96266893
51CAMK2D0.93151732
52DAPK20.91513144
53RET0.90924787
54PTK2B0.90161163
55PDPK10.89615055
56ICK0.89200584
57CDC42BPA0.88793372
58NTRK10.87904746
59EPHB10.86437060
60MAP2K40.86192711
61CDK190.85981604
62STK240.85736445
63FER0.85632416
64PDK10.83152015
65MET0.82700118
66PRKAA10.82278910
67SGK30.81165971
68PNCK0.79713134
69PDGFRA0.78718447
70MST1R0.77396322
71OXSR10.76781492
72CAMKK10.76399193
73STK110.72735588
74WEE10.71865778
75TBK10.68813068
76CAMK2A0.68697456
77NME10.68240187
78GRK50.68190339
79ROCK10.67158150
80CSK0.66844944
81UHMK10.66274759
82CDK50.65272563
83BCKDK0.65226364
84PIK3CG0.64895381
85SGK2230.64307062
86SGK4940.64307062
87PIK3CA0.64064209
88MARK20.63957142
89LATS10.63271820
90FGFR30.63198589
91NEK10.60459131
92MAP2K20.58932591
93PRKCI0.57206831
94MAP3K110.56924643
95TYRO30.56677296
96PRKD20.54626677
97EPHA30.54024037
98PTK60.53928908
99MAP2K30.53437658
100CAMK2G0.52315601
101NLK0.51929230
102RPS6KA20.51918364
103MAPK120.51817002
104MARK10.51099949
105PKN10.49089431
106SMG10.48152235
107MAP2K60.47567439
108MAPK100.47277671
109PRKCE0.47185214
110PRKAA20.46903484
111NEK90.46606724
112MAP3K30.46263188
113CAMK40.45617167
114SGK20.45504934
115DYRK1A0.45270791
116TESK10.45070430
117TAOK20.45026564
118MAP2K10.44542317
119SGK10.44403506
120MINK10.43617786
121CAMKK20.43531001
122DYRK1B0.43287705
123IRAK10.42977951
124CAMK10.41826058
125MAP3K120.41541117
126MAPK130.41194981
127MAPK70.38268464
128ERBB20.37976202
129STK38L0.37650613
130CAMK2B0.37185532
131RPS6KA30.37177338
132JAK10.37004471
133FRK0.36933825
134ARAF0.36302373
135PRKACA0.36124672
136LRRK20.35809964
137PRKACG0.35515198
138AKT20.35292382
139LATS20.34877066
140PRKG10.33407442

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine metabolism_Homo sapiens_hsa003602.99819486
2Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.80927519
3Histidine metabolism_Homo sapiens_hsa003402.77179630
4Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.31004240
5Dilated cardiomyopathy_Homo sapiens_hsa054142.28906311
6Insulin secretion_Homo sapiens_hsa049112.25823091
7Cardiac muscle contraction_Homo sapiens_hsa042602.24847855
8Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.03775171
9Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.88918057
10Tyrosine metabolism_Homo sapiens_hsa003501.88414828
11beta-Alanine metabolism_Homo sapiens_hsa004101.87426360
12Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.68594044
13Chemical carcinogenesis_Homo sapiens_hsa052041.68585267
14Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.67939653
15Gastric acid secretion_Homo sapiens_hsa049711.63723128
16Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.63114304
17Maturity onset diabetes of the young_Homo sapiens_hsa049501.62670148
18Type II diabetes mellitus_Homo sapiens_hsa049301.57803352
19Propanoate metabolism_Homo sapiens_hsa006401.56857230
20Amphetamine addiction_Homo sapiens_hsa050311.56346168
21Circadian entrainment_Homo sapiens_hsa047131.55171425
22ABC transporters_Homo sapiens_hsa020101.54638794
23Olfactory transduction_Homo sapiens_hsa047401.52181556
24Glucagon signaling pathway_Homo sapiens_hsa049221.46489099
25Renin secretion_Homo sapiens_hsa049241.45387514
26cGMP-PKG signaling pathway_Homo sapiens_hsa040221.44307181
27Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.43816583
28Long-term potentiation_Homo sapiens_hsa047201.41392286
29Aldosterone synthesis and secretion_Homo sapiens_hsa049251.37885289
30Pancreatic secretion_Homo sapiens_hsa049721.30112671
31Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.28768123
32Oxytocin signaling pathway_Homo sapiens_hsa049211.28522953
33Salivary secretion_Homo sapiens_hsa049701.27748741
34Calcium signaling pathway_Homo sapiens_hsa040201.23521913
35Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.22835550
36Vascular smooth muscle contraction_Homo sapiens_hsa042701.22707841
37Fatty acid degradation_Homo sapiens_hsa000711.21770633
38Circadian rhythm_Homo sapiens_hsa047101.20410958
39Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.19825073
40Cholinergic synapse_Homo sapiens_hsa047251.19049051
41Cocaine addiction_Homo sapiens_hsa050301.17914419
42GABAergic synapse_Homo sapiens_hsa047271.16860849
432-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.15903496
44Dorso-ventral axis formation_Homo sapiens_hsa043201.15584504
45Taste transduction_Homo sapiens_hsa047421.14686759
46Synaptic vesicle cycle_Homo sapiens_hsa047211.13730781
47Insulin resistance_Homo sapiens_hsa049311.13369336
48Dopaminergic synapse_Homo sapiens_hsa047281.12685120
49Estrogen signaling pathway_Homo sapiens_hsa049151.11006714
50cAMP signaling pathway_Homo sapiens_hsa040241.10592330
51Glutamatergic synapse_Homo sapiens_hsa047241.10270957
52Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.10263397
53Choline metabolism in cancer_Homo sapiens_hsa052311.07473077
54Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.06160135
55Morphine addiction_Homo sapiens_hsa050321.05297342
56Adipocytokine signaling pathway_Homo sapiens_hsa049201.03118652
57Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.02951385
58Carbohydrate digestion and absorption_Homo sapiens_hsa049731.02497566
59GnRH signaling pathway_Homo sapiens_hsa049121.01193593
60Sphingolipid metabolism_Homo sapiens_hsa006000.95838661
61Insulin signaling pathway_Homo sapiens_hsa049100.93560775
62Thyroid hormone synthesis_Homo sapiens_hsa049180.93097037
63Glycerophospholipid metabolism_Homo sapiens_hsa005640.93032209
64Nitrogen metabolism_Homo sapiens_hsa009100.92036328
65Linoleic acid metabolism_Homo sapiens_hsa005910.91576353
66Alzheimers disease_Homo sapiens_hsa050100.89729663
67Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.87981624
68Fatty acid metabolism_Homo sapiens_hsa012120.86859925
69Phosphatidylinositol signaling system_Homo sapiens_hsa040700.86770031
70Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.86129512
71Pyruvate metabolism_Homo sapiens_hsa006200.82257557
72Parkinsons disease_Homo sapiens_hsa050120.78519078
73Gap junction_Homo sapiens_hsa045400.77012892
74Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.76222497
75AMPK signaling pathway_Homo sapiens_hsa041520.76126754
76Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.75654677
77Longevity regulating pathway - mammal_Homo sapiens_hsa042110.75428720
78Butanoate metabolism_Homo sapiens_hsa006500.72964680
79Carbon metabolism_Homo sapiens_hsa012000.71874163
80Glutathione metabolism_Homo sapiens_hsa004800.70598260
81Thyroid hormone signaling pathway_Homo sapiens_hsa049190.69876585
82Oxidative phosphorylation_Homo sapiens_hsa001900.69684672
83Tight junction_Homo sapiens_hsa045300.64400104
84Serotonergic synapse_Homo sapiens_hsa047260.63383534
85Leukocyte transendothelial migration_Homo sapiens_hsa046700.63297447
86Bile secretion_Homo sapiens_hsa049760.63065500
87Vibrio cholerae infection_Homo sapiens_hsa051100.62946755
88Collecting duct acid secretion_Homo sapiens_hsa049660.61462675
89ErbB signaling pathway_Homo sapiens_hsa040120.60837551
90Melanogenesis_Homo sapiens_hsa049160.60009409
91Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.59953542
92Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.59374295
93Focal adhesion_Homo sapiens_hsa045100.57289446
94VEGF signaling pathway_Homo sapiens_hsa043700.56675809
95PPAR signaling pathway_Homo sapiens_hsa033200.56199290
96Mineral absorption_Homo sapiens_hsa049780.55638323
97Long-term depression_Homo sapiens_hsa047300.55608628
98Ovarian steroidogenesis_Homo sapiens_hsa049130.55604153
99Arginine and proline metabolism_Homo sapiens_hsa003300.55367573
100Renal cell carcinoma_Homo sapiens_hsa052110.54487696
101MAPK signaling pathway_Homo sapiens_hsa040100.53970335
102Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.53280008
103Fatty acid biosynthesis_Homo sapiens_hsa000610.52959506
104Notch signaling pathway_Homo sapiens_hsa043300.52438948
105mTOR signaling pathway_Homo sapiens_hsa041500.52350761
106Inositol phosphate metabolism_Homo sapiens_hsa005620.51457581
107Sulfur metabolism_Homo sapiens_hsa009200.51119584
108Phospholipase D signaling pathway_Homo sapiens_hsa040720.50441548
109Sphingolipid signaling pathway_Homo sapiens_hsa040710.50188225
110Nicotine addiction_Homo sapiens_hsa050330.49863998
111Hepatitis C_Homo sapiens_hsa051600.48293164
112Glycerolipid metabolism_Homo sapiens_hsa005610.47530731
113Prion diseases_Homo sapiens_hsa050200.47154115
114Arginine biosynthesis_Homo sapiens_hsa002200.46689325
115Starch and sucrose metabolism_Homo sapiens_hsa005000.46643046
116Amoebiasis_Homo sapiens_hsa051460.46243686
117Glioma_Homo sapiens_hsa052140.45976170
118Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.45335035
119Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.43539560
120Regulation of autophagy_Homo sapiens_hsa041400.42864180
121Protein digestion and absorption_Homo sapiens_hsa049740.42721217
122Huntingtons disease_Homo sapiens_hsa050160.42518528
123Retinol metabolism_Homo sapiens_hsa008300.42302301
124Caffeine metabolism_Homo sapiens_hsa002320.41430825
125Endocytosis_Homo sapiens_hsa041440.41236579
126Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.41066435
127Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.37707406
128alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.36631275
129Fatty acid elongation_Homo sapiens_hsa000620.35337063

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