DEPDC1B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein localization to kinetochore (GO:0034501)6.40849313
2protein localization to chromosome, centromeric region (GO:0071459)5.72172521
3mitotic sister chromatid segregation (GO:0000070)5.59875889
4DNA unwinding involved in DNA replication (GO:0006268)5.54836494
5sister chromatid segregation (GO:0000819)5.30082341
6regulation of attachment of spindle microtubules to kinetochore (GO:0051988)5.17436643
7mitotic metaphase plate congression (GO:0007080)4.83823198
8mitotic chromosome condensation (GO:0007076)4.80648466
9DNA strand elongation involved in DNA replication (GO:0006271)4.79716085
10attachment of spindle microtubules to kinetochore (GO:0008608)4.77707222
11kinetochore organization (GO:0051383)4.66441887
12DNA strand elongation (GO:0022616)4.58153521
13regulation of spindle organization (GO:0090224)4.52553465
14telomere maintenance via semi-conservative replication (GO:0032201)4.51339390
15CENP-A containing nucleosome assembly (GO:0034080)4.43812381
16chromatin remodeling at centromere (GO:0031055)4.33628406
17metaphase plate congression (GO:0051310)4.28216310
18mitotic recombination (GO:0006312)4.26002779
19establishment of chromosome localization (GO:0051303)4.24571390
20DNA replication initiation (GO:0006270)4.22421348
21positive regulation of chromosome segregation (GO:0051984)4.16582229
22DNA replication-dependent nucleosome organization (GO:0034723)4.10937831
23DNA replication-dependent nucleosome assembly (GO:0006335)4.10937831
24DNA replication checkpoint (GO:0000076)4.09203910
25telomere maintenance via recombination (GO:0000722)4.08468147
26protein localization to chromosome (GO:0034502)3.95721723
27kinetochore assembly (GO:0051382)3.92792812
28mitotic nuclear envelope disassembly (GO:0007077)3.92299296
29DNA replication-independent nucleosome organization (GO:0034724)3.91349338
30DNA replication-independent nucleosome assembly (GO:0006336)3.91349338
31regulation of chromosome segregation (GO:0051983)3.81603192
32regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.81402849
33histone exchange (GO:0043486)3.80184075
34microtubule depolymerization (GO:0007019)3.74963462
35spindle checkpoint (GO:0031577)3.70744326
36chromosome segregation (GO:0007059)3.67389534
37nuclear pore organization (GO:0006999)3.66979141
38DNA topological change (GO:0006265)3.65395622
39membrane disassembly (GO:0030397)3.60101638
40nuclear envelope disassembly (GO:0051081)3.60101638
41meiotic chromosome segregation (GO:0045132)3.59892824
42regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.58371752
43nuclear pore complex assembly (GO:0051292)3.57975777
44regulation of mitotic spindle organization (GO:0060236)3.57474601
45mitotic G2/M transition checkpoint (GO:0044818)3.56688134
46negative regulation of mitosis (GO:0045839)3.55605186
47telomere maintenance via telomere lengthening (GO:0010833)3.55139571
48regulation of exit from mitosis (GO:0007096)3.53438221
49DNA double-strand break processing (GO:0000729)3.50833516
50chromosome condensation (GO:0030261)3.49661829
51DNA duplex unwinding (GO:0032508)3.49379856
52DNA geometric change (GO:0032392)3.49373023
53mitotic sister chromatid cohesion (GO:0007064)3.48411525
54nucleotide-excision repair, DNA gap filling (GO:0006297)3.48348096
55positive regulation of mitotic sister chromatid separation (GO:1901970)3.47833244
56positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.47833244
57positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.47833244
58replication fork processing (GO:0031297)3.44894664
59negative regulation of chromosome segregation (GO:0051985)3.43912400
60purine nucleobase biosynthetic process (GO:0009113)3.43528791
61negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.39187040
62negative regulation of sister chromatid segregation (GO:0033046)3.39187040
63negative regulation of mitotic sister chromatid separation (GO:2000816)3.39187040
64negative regulation of mitotic sister chromatid segregation (GO:0033048)3.39187040
65spindle assembly checkpoint (GO:0071173)3.38757917
66regulation of centrosome cycle (GO:0046605)3.38428919
67DNA ligation (GO:0006266)3.38222889
68non-recombinational repair (GO:0000726)3.35251385
69double-strand break repair via nonhomologous end joining (GO:0006303)3.35251385
70regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.34262783
71regulation of mitotic spindle checkpoint (GO:1903504)3.34262783
72negative regulation of DNA-dependent DNA replication (GO:2000104)3.33385100
73anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.32641002
74IMP biosynthetic process (GO:0006188)3.32111386
75establishment of viral latency (GO:0019043)3.31866299
76chromatin assembly or disassembly (GO:0006333)3.30540234
77regulation of mitotic metaphase/anaphase transition (GO:0030071)3.30440012
78heterochromatin organization (GO:0070828)3.29223139
79negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.29035353
80mitotic spindle checkpoint (GO:0071174)3.27487285
81mitotic spindle assembly checkpoint (GO:0007094)3.27311843
82regulation of histone H3-K9 methylation (GO:0051570)3.24856751
83maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.23700737
84regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.22794323
85histone-serine phosphorylation (GO:0035404)3.22274016
86regulation of mitotic sister chromatid separation (GO:0010965)3.21822203
87regulation of mitotic sister chromatid segregation (GO:0033047)3.21822203
88regulation of sister chromatid segregation (GO:0033045)3.21822203
89regulation of sister chromatid cohesion (GO:0007063)3.21684955
90regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.21410337
91regulation of telomere maintenance via telomerase (GO:0032210)3.21356389
92DNA conformation change (GO:0071103)3.20154179
93pore complex assembly (GO:0046931)3.19344151
94regulation of DNA endoreduplication (GO:0032875)3.15583219
95nucleobase biosynthetic process (GO:0046112)3.15202972
96somatic diversification of immune receptors via somatic mutation (GO:0002566)3.13894097
97somatic hypermutation of immunoglobulin genes (GO:0016446)3.13894097
98negative regulation of nuclear division (GO:0051784)3.12384718
99negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435)3.12275306
100DNA strand renaturation (GO:0000733)3.10749062
101IMP metabolic process (GO:0046040)3.09854526
102negative regulation of cell division (GO:0051782)3.09112883
103protein complex localization (GO:0031503)3.08980296
104ribosomal small subunit assembly (GO:0000028)3.08412436
105ATP-dependent chromatin remodeling (GO:0043044)3.07911958
106DNA packaging (GO:0006323)3.07256559
107folic acid-containing compound biosynthetic process (GO:0009396)3.06825802
108ventricular cardiac muscle cell development (GO:0055015)3.05287331
109mitotic cell cycle (GO:0000278)3.04347400
110viral transcription (GO:0019083)3.02916925
111translational termination (GO:0006415)2.99346890
112establishment of mitotic spindle localization (GO:0040001)2.97847754
113telomere organization (GO:0032200)2.97674902
114regulation of spindle checkpoint (GO:0090231)2.96806785
115spindle assembly involved in mitosis (GO:0090307)2.96352868
116telomere maintenance (GO:0000723)2.96301356
117establishment of integrated proviral latency (GO:0075713)2.92712582
118nuclear envelope organization (GO:0006998)2.86578697
119spindle assembly (GO:0051225)2.86423489
120translesion synthesis (GO:0019985)2.86182330
121mitotic spindle organization (GO:0007052)2.85601093
122regulation of double-strand break repair via homologous recombination (GO:0010569)2.85587206
123protein K6-linked ubiquitination (GO:0085020)2.83148227
124DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.81145491
125regulation of centriole replication (GO:0046599)2.80885999

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* FOXM1_23109430_ChIP-Seq_U2OS_Human6.97700637
2* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.65194799
3* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human4.12629740
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.39402712
5* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.26284469
6MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.62392877
7* AR_21909140_ChIP-Seq_LNCAP_Human2.56631117
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.54823066
9MYC_19079543_ChIP-ChIP_MESCs_Mouse2.51695715
10SALL1_21062744_ChIP-ChIP_HESCs_Human2.47411165
11MYC_19030024_ChIP-ChIP_MESCs_Mouse2.40194770
12SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.39741729
13EST1_17652178_ChIP-ChIP_JURKAT_Human2.39547223
14MYC_18358816_ChIP-ChIP_MESCs_Mouse2.26274056
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.26100186
16MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.19675193
17EGR1_19374776_ChIP-ChIP_THP-1_Human2.13209387
18E2F1_21310950_ChIP-Seq_MCF-7_Human2.10215075
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.10017763
20XRN2_22483619_ChIP-Seq_HELA_Human2.08634406
21FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.07941432
22NELFA_20434984_ChIP-Seq_ESCs_Mouse2.01651594
23E2F7_22180533_ChIP-Seq_HELA_Human10.2971015
24ETS1_20019798_ChIP-Seq_JURKAT_Human1.98248706
25GABP_17652178_ChIP-ChIP_JURKAT_Human1.96849012
26HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.89262986
27VDR_23849224_ChIP-Seq_CD4+_Human1.80299026
28JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.76429889
29MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.75865411
30FOXP3_21729870_ChIP-Seq_TREG_Human1.72339349
31KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.71620151
32ELF1_17652178_ChIP-ChIP_JURKAT_Human1.69470666
33* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.65578397
34* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.64363758
35MYC_22102868_ChIP-Seq_BL_Human1.61143048
36NANOG_18555785_ChIP-Seq_MESCs_Mouse1.59139395
37DCP1A_22483619_ChIP-Seq_HELA_Human1.56288753
38NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.55120860
39TTF2_22483619_ChIP-Seq_HELA_Human1.54598565
40* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.53572842
41VDR_21846776_ChIP-Seq_THP-1_Human1.51407175
42ELK1_19687146_ChIP-ChIP_HELA_Human1.50749079
43* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.48564494
44CIITA_25753668_ChIP-Seq_RAJI_Human1.42751607
45POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.42666512
46THAP11_20581084_ChIP-Seq_MESCs_Mouse1.42076037
47* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.41030687
48KDM5A_27292631_Chip-Seq_BREAST_Human1.38778162
49SOX2_16153702_ChIP-ChIP_HESCs_Human1.38732297
50GABP_19822575_ChIP-Seq_HepG2_Human1.36954665
51SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.31446851
52NANOG_16153702_ChIP-ChIP_HESCs_Human1.31398157
53SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.30755673
54E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.29633595
55HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.28934857
56YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.28344728
57CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.27627525
58POU5F1_16153702_ChIP-ChIP_HESCs_Human1.26555393
59ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.26045876
60ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.24560162
61HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.22490982
62FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.20844817
63ERG_20887958_ChIP-Seq_HPC-7_Mouse1.20027642
64SOX2_18555785_ChIP-Seq_MESCs_Mouse1.19042965
65ZFX_18555785_ChIP-Seq_MESCs_Mouse1.18625018
66PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.18039435
67EWS_26573619_Chip-Seq_HEK293_Human1.16608350
68SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.14442136
69KLF4_18555785_ChIP-Seq_MESCs_Mouse1.13920798
70PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.07968030
71TFEB_21752829_ChIP-Seq_HELA_Human1.06146488
72SPI1_23547873_ChIP-Seq_NB4_Human1.06027822
73YY1_21170310_ChIP-Seq_MESCs_Mouse1.04631166
74POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.04562077
75* PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.04218114
76CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.04060527
77PADI4_21655091_ChIP-ChIP_MCF-7_Human1.00279033
78* MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.98720074
79IRF1_19129219_ChIP-ChIP_H3396_Human0.98548106
80* FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.97441809
81MYB_21317192_ChIP-Seq_ERMYB_Mouse0.97219261
82KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.96269217
83TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94939703
84DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.93971599
85POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.92636683
86CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.92113562
87RBPJ_22232070_ChIP-Seq_NCS_Mouse0.91163868
88* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.90255110
89SOX17_20123909_ChIP-Seq_XEN_Mouse0.90227953
90CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.89251989
91FUS_26573619_Chip-Seq_HEK293_Human0.89136082
92STAT3_1855785_ChIP-Seq_MESCs_Mouse0.88901272
93E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.88199630
94MYC_18940864_ChIP-ChIP_HL60_Human0.86810837
95CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.86579803
96UTX_26944678_Chip-Seq_JUKART_Human0.85958455
97* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.85517188
98* KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.85500982
99NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.84472977
100CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.83134544
101VDR_22108803_ChIP-Seq_LS180_Human0.81983845
102DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.81738549
103* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.81141927
104BRD4_27068464_Chip-Seq_AML-cells_Mouse0.80190679
105NANOG_21062744_ChIP-ChIP_HESCs_Human0.79872102
106SRF_21415370_ChIP-Seq_HL-1_Mouse0.78863618
107HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.78810067
108GATA1_22383799_ChIP-Seq_G1ME_Mouse0.78605193
109* MYB_26560356_Chip-Seq_TH2_Human0.78331913
110MAF_26560356_Chip-Seq_TH1_Human0.78195540
111RUNX1_22412390_ChIP-Seq_EML_Mouse0.78159752
112* SCL_19346495_ChIP-Seq_HPC-7_Human0.77861697
113NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.77193252
114KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.76010746
115KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.76010746
116KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.76010746
117TCF3_18692474_ChIP-Seq_MEFs_Mouse0.75890436
118MYB_26560356_Chip-Seq_TH1_Human0.75078511
119ZNF274_21170338_ChIP-Seq_K562_Hela0.74591771
120VDR_24763502_ChIP-Seq_THP-1_Human0.73459681
121ESR1_15608294_ChIP-ChIP_MCF-7_Human0.72723225
122SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.72623060
123TP63_19390658_ChIP-ChIP_HaCaT_Human0.71547013
124HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.71081239
125NOTCH1_21737748_ChIP-Seq_TLL_Human0.68911473
126GATA1_26923725_Chip-Seq_HPCs_Mouse0.62913764
127NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.61945229

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.26117646
2MP0003111_abnormal_nucleus_morphology5.03361157
3MP0008057_abnormal_DNA_replication4.98505138
4MP0010094_abnormal_chromosome_stability4.96262997
5MP0003077_abnormal_cell_cycle4.29927183
6MP0004957_abnormal_blastocyst_morpholog4.05097957
7MP0008058_abnormal_DNA_repair2.72197249
8MP0008932_abnormal_embryonic_tissue2.62137797
9MP0002396_abnormal_hematopoietic_system2.55366655
10MP0008007_abnormal_cellular_replicative2.52072647
11MP0003941_abnormal_skin_development2.47264187
12MP0009697_abnormal_copulation2.45339809
13MP0001730_embryonic_growth_arrest2.44598173
14MP0006292_abnormal_olfactory_placode2.41825243
15MP0000350_abnormal_cell_proliferation2.28255813
16MP0010307_abnormal_tumor_latency2.05771701
17MP0003123_paternal_imprinting1.84184517
18MP0001697_abnormal_embryo_size1.77539926
19MP0000490_abnormal_crypts_of1.74570665
20MP0010352_gastrointestinal_tract_polyps1.65041867
21MP0001672_abnormal_embryogenesis/_devel1.63859552
22MP0005380_embryogenesis_phenotype1.63859552
23MP0002085_abnormal_embryonic_tissue1.58646543
24MP0008877_abnormal_DNA_methylation1.58322535
25MP0005076_abnormal_cell_differentiation1.57989160
26MP0002080_prenatal_lethality1.57510375
27MP0004808_abnormal_hematopoietic_stem1.55642366
28MP0000313_abnormal_cell_death1.55502633
29MP0002019_abnormal_tumor_incidence1.43900777
30MP0002938_white_spotting1.42463633
31MP0004147_increased_porphyrin_level1.41899431
32MP0003984_embryonic_growth_retardation1.39916513
33MP0002398_abnormal_bone_marrow1.39783170
34MP0009278_abnormal_bone_marrow1.39687555
35MP0002084_abnormal_developmental_patter1.37953470
36MP0006035_abnormal_mitochondrial_morpho1.35956156
37MP0003656_abnormal_erythrocyte_physiolo1.34735617
38MP0002086_abnormal_extraembryonic_tissu1.34590847
39MP0002088_abnormal_embryonic_growth/wei1.34504127
40MP0004197_abnormal_fetal_growth/weight/1.34270814
41MP0002697_abnormal_eye_size1.34249842
42MP0003786_premature_aging1.33720736
43MP0000703_abnormal_thymus_morphology1.33666527
44MP0003136_yellow_coat_color1.31047082
45MP0005397_hematopoietic_system_phenotyp1.30392136
46MP0001545_abnormal_hematopoietic_system1.30392136
47MP0002722_abnormal_immune_system1.29405332
48MP0001286_abnormal_eye_development1.28650447
49MP0003806_abnormal_nucleotide_metabolis1.28300617
50MP0000566_synostosis1.25804020
51MP0008789_abnormal_olfactory_epithelium1.25236565
52MP0000689_abnormal_spleen_morphology1.23769513
53MP0006072_abnormal_retinal_apoptosis1.19651516
54MP0001529_abnormal_vocalization1.17972800
55MP0002653_abnormal_ependyma_morphology1.16156839
56MP0003890_abnormal_embryonic-extraembry1.15532540
57MP0001293_anophthalmia1.14742353
58MP0001929_abnormal_gametogenesis1.14077001
59MP0002210_abnormal_sex_determination1.12424931
60MP0003121_genomic_imprinting1.11301492
61MP0003718_maternal_effect1.09761364
62MP0001145_abnormal_male_reproductive1.08078667
63MP0002429_abnormal_blood_cell1.07176642
64MP0009333_abnormal_splenocyte_physiolog1.03833462
65MP0003937_abnormal_limbs/digits/tail_de1.02522777
66MP0000537_abnormal_urethra_morphology1.01214846
67MP0003119_abnormal_digestive_system1.01055164
68MP0003763_abnormal_thymus_physiology1.00898704
69MP0003950_abnormal_plasma_membrane1.00023397
70MP0002233_abnormal_nose_morphology0.99909301
71MP0005499_abnormal_olfactory_system0.97628547
72MP0005394_taste/olfaction_phenotype0.97628547
73MP0006054_spinal_hemorrhage0.97235185
74MP0000049_abnormal_middle_ear0.95836973
75MP0000716_abnormal_immune_system0.94988230
76MP0003567_abnormal_fetal_cardiomyocyte0.94108278
77MP0000465_gastrointestinal_hemorrhage0.93549466
78MP0001346_abnormal_lacrimal_gland0.92979947
79MP0003861_abnormal_nervous_system0.89786738
80MP0003303_peritoneal_inflammation0.88981703
81MP0000358_abnormal_cell_content/0.88930426
82MP0001915_intracranial_hemorrhage0.87128247
83MP0009672_abnormal_birth_weight0.86349609
84MP0005621_abnormal_cell_physiology0.86092710
85MP0000653_abnormal_sex_gland0.85979654
86MP0002420_abnormal_adaptive_immunity0.85321600
87MP0000579_abnormal_nail_morphology0.84508298
88MP0001819_abnormal_immune_cell0.83361548
89MP0002102_abnormal_ear_morphology0.82338736
90MP0002111_abnormal_tail_morphology0.82212998
91MP0002405_respiratory_system_inflammati0.81610055
92MP0000428_abnormal_craniofacial_morphol0.81198934
93MP0005395_other_phenotype0.80930288
94MP0005023_abnormal_wound_healing0.80671187
95MP0005384_cellular_phenotype0.80336656
96MP0001188_hyperpigmentation0.80228490
97MP0005410_abnormal_fertilization0.79825497
98MP0004133_heterotaxia0.79562318
99MP0000383_abnormal_hair_follicle0.78941000
100MP0003566_abnormal_cell_adhesion0.78670362
101MP0003315_abnormal_perineum_morphology0.78109892
102MP0003755_abnormal_palate_morphology0.77792005
103MP0001800_abnormal_humoral_immune0.76260611
104MP0002132_abnormal_respiratory_system0.75672052
105MP0003186_abnormal_redox_activity0.75563364
106MP0000685_abnormal_immune_system0.74975474
107MP0002092_abnormal_eye_morphology0.74909335
108MP0002234_abnormal_pharynx_morphology0.74729102
109MP0009053_abnormal_anal_canal0.74119315
110MP0001119_abnormal_female_reproductive0.74065509
111MP0002452_abnormal_antigen_presenting0.73935211
112MP0000858_altered_metastatic_potential0.73270259
113MP0005391_vision/eye_phenotype0.72836691
114MP0010030_abnormal_orbit_morphology0.70056048
115MP0001727_abnormal_embryo_implantation0.69643938
116MP0003698_abnormal_male_reproductive0.69635432
117MP0006036_abnormal_mitochondrial_physio0.69577302
118MP0000432_abnormal_head_morphology0.69320679
119MP0000647_abnormal_sebaceous_gland0.68905231
120MP0009703_decreased_birth_body0.68094501
121MP0002161_abnormal_fertility/fecundity0.67498172
122MP0000372_irregular_coat_pigmentation0.66506863
123MP0002751_abnormal_autonomic_nervous0.66352949
124MP0005671_abnormal_response_to0.65881228
125MP0003938_abnormal_ear_development0.64575268
126MP0000477_abnormal_intestine_morphology0.64465649
127MP0005464_abnormal_platelet_physiology0.63945110
128MP0003448_altered_tumor_morphology0.63727492
129MP0003699_abnormal_female_reproductive0.62058564
130MP0000631_abnormal_neuroendocrine_gland0.61781580
131MP0002254_reproductive_system_inflammat0.61402298
132MP0002419_abnormal_innate_immunity0.61205292
133MP0001177_atelectasis0.60966806
134MP0005025_abnormal_response_to0.60910441
135MP0003436_decreased_susceptibility_to0.59697773
136MP0003935_abnormal_craniofacial_develop0.59592941
137MP0005174_abnormal_tail_pigmentation0.59492681
138MP0009785_altered_susceptibility_to0.58984566
139MP0002723_abnormal_immune_serum0.58974108
140MP0005501_abnormal_skin_physiology0.58355519
141MP0002796_impaired_skin_barrier0.58173618
142MP0001849_ear_inflammation0.57693387
143MP0002095_abnormal_skin_pigmentation0.57508767
144MP0005408_hypopigmentation0.55763282
145MP0001299_abnormal_eye_distance/0.55082268
146MP0002090_abnormal_vision0.51189009

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)5.20371886
2Chromsome breakage (HP:0040012)5.17204486
3Reticulocytopenia (HP:0001896)4.85190039
4Duplicated collecting system (HP:0000081)3.84271901
5Abnormality of chromosome stability (HP:0003220)3.66197738
6Ectopic kidney (HP:0000086)3.54703355
7Meckel diverticulum (HP:0002245)3.33034158
8Cortical dysplasia (HP:0002539)3.32133773
9Abnormality of the renal collecting system (HP:0004742)3.25179307
10Abnormality of the ileum (HP:0001549)3.23773893
11Abnormality of cells of the erythroid lineage (HP:0012130)3.22946520
12Abnormality of the preputium (HP:0100587)3.18526544
13Aplasia/Hypoplasia of the uvula (HP:0010293)3.18384179
14Duodenal stenosis (HP:0100867)3.13647470
15Small intestinal stenosis (HP:0012848)3.13647470
16Absent radius (HP:0003974)2.99882168
17Abnormal number of erythroid precursors (HP:0012131)2.97993076
18Pancreatic islet-cell hyperplasia (HP:0004510)2.93874821
19Birth length less than 3rd percentile (HP:0003561)2.93871139
20Myelodysplasia (HP:0002863)2.93258322
21Medulloblastoma (HP:0002885)2.88492300
22Abnormal lung lobation (HP:0002101)2.88395060
23Carpal bone hypoplasia (HP:0001498)2.87712624
2411 pairs of ribs (HP:0000878)2.83788271
25Aplastic anemia (HP:0001915)2.80135140
26Absent forearm bone (HP:0003953)2.76307114
27Aplasia involving forearm bones (HP:0009822)2.76307114
28Bone marrow hypocellularity (HP:0005528)2.73225983
29Impulsivity (HP:0100710)2.68905388
30Increased nuchal translucency (HP:0010880)2.64851303
31Abnormality of reticulocytes (HP:0004312)2.63342200
32Abnormality of the duodenum (HP:0002246)2.63191225
33Selective tooth agenesis (HP:0001592)2.61748154
34Breast hypoplasia (HP:0003187)2.60609110
35Sloping forehead (HP:0000340)2.57558857
36Abnormality of the heme biosynthetic pathway (HP:0010472)2.54275017
37Agnosia (HP:0010524)2.51935875
38Short 4th metacarpal (HP:0010044)2.50498512
39Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.50498512
40Embryonal neoplasm (HP:0002898)2.50290968
41Absent thumb (HP:0009777)2.46730731
42Patellar aplasia (HP:0006443)2.45946206
43Macrocytic anemia (HP:0001972)2.45397027
44Aplasia/Hypoplasia of the sternum (HP:0006714)2.44396031
45Aplasia/Hypoplasia of the sacrum (HP:0008517)2.44063458
46Volvulus (HP:0002580)2.43974540
47Nephroblastoma (Wilms tumor) (HP:0002667)2.43689647
48Aplasia/Hypoplasia of the patella (HP:0006498)2.42585630
49Ependymoma (HP:0002888)2.40396515
50Hypoplasia of the capital femoral epiphysis (HP:0003090)2.39127235
51Neoplasm of the colon (HP:0100273)2.35210803
52Septo-optic dysplasia (HP:0100842)2.34756752
53Pallor (HP:0000980)2.32061743
54Basal cell carcinoma (HP:0002671)2.28682796
55Cellulitis (HP:0100658)2.27940146
56Horseshoe kidney (HP:0000085)2.26876647
57Proximal placement of thumb (HP:0009623)2.24295644
58Abnormality of the carotid arteries (HP:0005344)2.23927863
59Colon cancer (HP:0003003)2.21639328
60Embryonal renal neoplasm (HP:0011794)2.21635481
61Poikilocytosis (HP:0004447)2.21271364
62Tracheoesophageal fistula (HP:0002575)2.20000843
63Cafe-au-lait spot (HP:0000957)2.19860774
64Intestinal atresia (HP:0011100)2.19759422
65Abnormality of DNA repair (HP:0003254)2.19467121
66Cerebral hypomyelination (HP:0006808)2.19040267
67Short thumb (HP:0009778)2.16524618
68Abnormality of chromosome segregation (HP:0002916)2.16414410
69Oral leukoplakia (HP:0002745)2.14997783
70Recurrent abscess formation (HP:0002722)2.14772069
71Triphalangeal thumb (HP:0001199)2.12639805
72Glioma (HP:0009733)2.11054114
73Abnormality of pyrimidine metabolism (HP:0004353)2.10298433
74Deviation of the thumb (HP:0009603)2.08847265
75Missing ribs (HP:0000921)2.08736613
76Hypoplastic pelvis (HP:0008839)2.08719713
77Abnormality of the labia minora (HP:0012880)2.07857750
78Abnormal number of incisors (HP:0011064)2.07580821
79Metaphyseal cupping (HP:0003021)2.05915769
80Multiple enchondromatosis (HP:0005701)2.05550841
81Supernumerary spleens (HP:0009799)2.05367131
82Clubbing of toes (HP:0100760)2.02899344
83Rough bone trabeculation (HP:0100670)2.02014747
84Choanal atresia (HP:0000453)2.01851451
85Amaurosis fugax (HP:0100576)2.01184108
86Combined immunodeficiency (HP:0005387)2.00654867
87IgM deficiency (HP:0002850)2.00463898
88Rhabdomyosarcoma (HP:0002859)2.00198808
89Small epiphyses (HP:0010585)1.99140791
90High pitched voice (HP:0001620)1.98114236
91Absent septum pellucidum (HP:0001331)1.97784760
92Abnormality of the septum pellucidum (HP:0007375)1.96938146
93Ureteral duplication (HP:0000073)1.96417751
94Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.96256051
95Abnormality of the anterior horn cell (HP:0006802)1.91637947
96Degeneration of anterior horn cells (HP:0002398)1.91637947
97High anterior hairline (HP:0009890)1.90937029
98Duplication of thumb phalanx (HP:0009942)1.90616193
99Asplenia (HP:0001746)1.90224988
100Lymphoma (HP:0002665)1.89907925
101Arteriovenous malformation (HP:0100026)1.88604733
102Cellular immunodeficiency (HP:0005374)1.88590600
103Esophageal atresia (HP:0002032)1.88243351
104Neoplasm of the pancreas (HP:0002894)1.87717922
105Premature graying of hair (HP:0002216)1.86921832
106Prominent nose (HP:0000448)1.86482013
107Irregular epiphyses (HP:0010582)1.85278182
108Ovarian neoplasm (HP:0100615)1.84303155
109Microvesicular hepatic steatosis (HP:0001414)1.84086751
110Broad distal phalanx of finger (HP:0009836)1.83750686
111Hypoplasia of the pons (HP:0012110)1.81548544
112Abnormality of cochlea (HP:0000375)1.81012881
113Squamous cell carcinoma (HP:0002860)1.80551755
114Abnormality of the pons (HP:0007361)1.79738763
115Absent epiphyses (HP:0010577)1.79170242
116Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.79170242
117Pancytopenia (HP:0001876)1.79106243
118Obstructive lung disease (HP:0006536)1.78231607
119Chronic obstructive pulmonary disease (HP:0006510)1.78231607
120Severe combined immunodeficiency (HP:0004430)1.76225388
121Abnormality of methionine metabolism (HP:0010901)1.74766203
122Dandy-Walker malformation (HP:0001305)1.74109621
123Facial hemangioma (HP:0000329)1.73755317
124Hyperglycinemia (HP:0002154)1.73410096
125Abnormality of the astrocytes (HP:0100707)1.72583387
126Astrocytoma (HP:0009592)1.72583387
127Acute encephalopathy (HP:0006846)1.70584173
128Gastrointestinal atresia (HP:0002589)1.70252517
129Abnormality of glycolysis (HP:0004366)1.70136542
130Increased serum pyruvate (HP:0003542)1.67783815
131Neoplasm of striated muscle (HP:0009728)1.66928840
132Abnormality of endocrine pancreas physiology (HP:0012093)1.65298449
133Abnormality of the pancreatic islet cells (HP:0006476)1.65298449
134Spastic diplegia (HP:0001264)1.64149554
135Holoprosencephaly (HP:0001360)1.62539823
136Acute necrotizing encephalopathy (HP:0006965)1.61764634
137Pendular nystagmus (HP:0012043)1.59146638
138Abnormality of serum amino acid levels (HP:0003112)1.57054710
139Abnormality of serine family amino acid metabolism (HP:0010894)1.54282563
140Abnormality of glycine metabolism (HP:0010895)1.54282563
141Bifid tongue (HP:0010297)1.53473202
142Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.52505379

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.42867810
2CDC74.67158061
3WEE14.27668446
4NEK23.08778238
5TESK22.65992620
6TTK2.56419823
7EIF2AK12.39073411
8BRSK22.38887004
9VRK22.23414603
10STK102.14774463
11STK42.10900453
12PLK12.02585717
13NEK11.97718711
14CLK11.96164272
15SRPK11.91883822
16CDK121.89850206
17TLK11.80742880
18AURKB1.76183951
19EEF2K1.68481693
20PBK1.65956593
21MAP3K81.62285021
22MKNK11.61574898
23PLK41.61222616
24BRSK11.58583519
25TAF11.49867533
26ATR1.49286284
27NUAK11.47116091
28CDK71.46544482
29VRK11.46323081
30CHEK21.46261294
31AURKA1.41007990
32RPS6KB21.39215409
33PLK31.38266077
34MAP3K101.37553527
35PASK1.33324743
36CCNB11.32467193
37TESK11.30828615
38CHEK11.30650415
39TRIM281.29563852
40CDK41.28599443
41TNIK1.26760203
42TSSK61.20937204
43MAP4K11.19679656
44PAK41.11988458
45DYRK31.10352209
46BRAF1.08820711
47MELK1.04751047
48EIF2AK31.03049121
49LATS10.94885314
50UHMK10.89405486
51WNK30.89292380
52EPHB10.88992055
53LIMK10.87072362
54PIM10.86996981
55CDK60.86615106
56GRK60.84776062
57BLK0.83930168
58ATM0.83082467
59PNCK0.81593419
60NME10.80189814
61LRRK20.79126287
62CDK20.78060638
63ACVR1B0.77804634
64NME20.77712576
65ALK0.76739920
66BMPR1B0.74912169
67MKNK20.74351763
68RPS6KA40.71533592
69CDK10.70573193
70MST40.69942696
71SCYL20.69721201
72PAK10.65912546
73ZAK0.64081649
74BTK0.63880176
75STK160.62529585
76TRPM70.62290588
77RPS6KA50.62130893
78STK390.61202819
79FGR0.59443761
80STK30.57789218
81IRAK40.56790020
82ICK0.54509663
83CDK80.54405388
84BCR0.54204969
85CDK150.53763455
86CDK11A0.53490623
87FLT30.53152424
88EIF2AK20.51694963
89PKN20.51357464
90BRD40.51142955
91PLK20.50831124
92CDK180.48564848
93FGFR10.48446150
94CSF1R0.46886631
95SMG10.46231091
96CSNK2A20.45743916
97OXSR10.45371591
98DYRK20.44789654
99CDK140.44291054
100KDR0.42561551
101ERBB40.41832217
102MARK30.41726325
103TGFBR10.41585583
104CSNK2A10.41168556
105PDK30.41105533
106PDK40.41105533
107EPHA20.40025546
108STK38L0.39448091
109CSNK1G10.39356624
110ERBB30.35675033
111CSNK1E0.35563847
112CDK30.33932495
113CSNK1D0.33129045
114PRKCI0.32268065
115TEC0.29120852
116CSK0.28856082
117MAPKAPK20.28548836
118TTN0.28485244
119ITK0.28461385
120LYN0.27686502
121PRKDC0.27292411
122NEK90.26765653
123CSNK1G30.26490270
124AKT20.24785803
125PDK20.24611208
126CDK90.22670351
127CDK190.20650280
128MAP3K40.19631158
129PRKCG0.17992154
130LATS20.17594668
131YES10.16922450
132CSNK1A1L0.16406962
133ADRBK20.15401986
134PKN10.15177363
135GSK3B0.14446931

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.28054736
2Mismatch repair_Homo sapiens_hsa034304.28223092
3Cell cycle_Homo sapiens_hsa041103.31948648
4Homologous recombination_Homo sapiens_hsa034403.31336658
5Spliceosome_Homo sapiens_hsa030403.13833443
6Base excision repair_Homo sapiens_hsa034103.08248922
7Ribosome_Homo sapiens_hsa030102.77669698
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.77468101
9Nucleotide excision repair_Homo sapiens_hsa034202.76286832
10RNA transport_Homo sapiens_hsa030132.75210922
11Fanconi anemia pathway_Homo sapiens_hsa034602.72529999
12Non-homologous end-joining_Homo sapiens_hsa034502.56923154
13One carbon pool by folate_Homo sapiens_hsa006702.50668591
14RNA polymerase_Homo sapiens_hsa030202.50525719
15Systemic lupus erythematosus_Homo sapiens_hsa053222.25115690
16Proteasome_Homo sapiens_hsa030502.14454530
17Pyrimidine metabolism_Homo sapiens_hsa002402.05991016
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.95385446
19Basal transcription factors_Homo sapiens_hsa030221.88263715
20mRNA surveillance pathway_Homo sapiens_hsa030151.78138714
21p53 signaling pathway_Homo sapiens_hsa041151.61923804
22RNA degradation_Homo sapiens_hsa030181.60484319
23Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.47295580
24Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.42681341
25Oocyte meiosis_Homo sapiens_hsa041141.33476801
26Viral carcinogenesis_Homo sapiens_hsa052031.32391261
27Propanoate metabolism_Homo sapiens_hsa006401.31759874
28Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.31404633
29Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.27392105
302-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.26773764
31Epstein-Barr virus infection_Homo sapiens_hsa051691.19017233
32Vitamin B6 metabolism_Homo sapiens_hsa007501.16932360
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.13338406
34Purine metabolism_Homo sapiens_hsa002301.05713530
35Steroid biosynthesis_Homo sapiens_hsa001001.04795440
36Pentose phosphate pathway_Homo sapiens_hsa000301.04234182
37Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.01984740
38Fatty acid elongation_Homo sapiens_hsa000621.00343702
39Alcoholism_Homo sapiens_hsa050341.00059823
40Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.99588735
41Parkinsons disease_Homo sapiens_hsa050120.96149292
42Herpes simplex infection_Homo sapiens_hsa051680.94980104
43Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.92370192
44MicroRNAs in cancer_Homo sapiens_hsa052060.85682531
45Primary immunodeficiency_Homo sapiens_hsa053400.85682107
46Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.84903059
47Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.82403147
48Oxidative phosphorylation_Homo sapiens_hsa001900.80347487
49Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.79505034
50HTLV-I infection_Homo sapiens_hsa051660.79478984
51Antigen processing and presentation_Homo sapiens_hsa046120.75415166
52Cyanoamino acid metabolism_Homo sapiens_hsa004600.74571941
53Transcriptional misregulation in cancer_Homo sapiens_hsa052020.71155809
54Glutathione metabolism_Homo sapiens_hsa004800.70804631
55Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.70752197
56Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.68490261
57Small cell lung cancer_Homo sapiens_hsa052220.67939777
58Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.67083797
59Biosynthesis of amino acids_Homo sapiens_hsa012300.64841923
60Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.61463421
61Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.59235564
62Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.55281211
63Selenocompound metabolism_Homo sapiens_hsa004500.54847400
64Apoptosis_Homo sapiens_hsa042100.53378192
65Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.51847804
66Leukocyte transendothelial migration_Homo sapiens_hsa046700.51746297
67Hedgehog signaling pathway_Homo sapiens_hsa043400.49184275
68Chronic myeloid leukemia_Homo sapiens_hsa052200.48536566
69Shigellosis_Homo sapiens_hsa051310.47779219
70Metabolic pathways_Homo sapiens_hsa011000.47741058
71Notch signaling pathway_Homo sapiens_hsa043300.46625924
72Cysteine and methionine metabolism_Homo sapiens_hsa002700.46516275
73Drug metabolism - other enzymes_Homo sapiens_hsa009830.46153686
74Hematopoietic cell lineage_Homo sapiens_hsa046400.46090377
75Fatty acid metabolism_Homo sapiens_hsa012120.45673991
76B cell receptor signaling pathway_Homo sapiens_hsa046620.44753470
77Wnt signaling pathway_Homo sapiens_hsa043100.44401759
78Protein export_Homo sapiens_hsa030600.43156017
79Pancreatic cancer_Homo sapiens_hsa052120.43140843
80Colorectal cancer_Homo sapiens_hsa052100.42946153
81Lysine degradation_Homo sapiens_hsa003100.42098295
82Folate biosynthesis_Homo sapiens_hsa007900.41621076
83Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.41161628
84Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.41092109
85NF-kappa B signaling pathway_Homo sapiens_hsa040640.40903343
86Alzheimers disease_Homo sapiens_hsa050100.39877780
87Hepatitis B_Homo sapiens_hsa051610.37840475
88Adherens junction_Homo sapiens_hsa045200.36217049
89N-Glycan biosynthesis_Homo sapiens_hsa005100.34225432
90Arginine and proline metabolism_Homo sapiens_hsa003300.34136721
91Carbon metabolism_Homo sapiens_hsa012000.33528503
92Pentose and glucuronate interconversions_Homo sapiens_hsa000400.32699211
93Legionellosis_Homo sapiens_hsa051340.32237606
94Viral myocarditis_Homo sapiens_hsa054160.31873921
95Measles_Homo sapiens_hsa051620.31803345
96Basal cell carcinoma_Homo sapiens_hsa052170.30249554
97Non-small cell lung cancer_Homo sapiens_hsa052230.29985469
98Thyroid cancer_Homo sapiens_hsa052160.29365194
99Leishmaniasis_Homo sapiens_hsa051400.29335059
100Pathways in cancer_Homo sapiens_hsa052000.28303657
101Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.27622865
102Intestinal immune network for IgA production_Homo sapiens_hsa046720.26805727
103Hippo signaling pathway_Homo sapiens_hsa043900.25779046
104TGF-beta signaling pathway_Homo sapiens_hsa043500.25721578
105Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.25083841
106Bladder cancer_Homo sapiens_hsa052190.24831816
107Butanoate metabolism_Homo sapiens_hsa006500.24512964
108Vitamin digestion and absorption_Homo sapiens_hsa049770.23580331
109Ether lipid metabolism_Homo sapiens_hsa005650.23124550
110Fatty acid degradation_Homo sapiens_hsa000710.22829724
111Regulation of actin cytoskeleton_Homo sapiens_hsa048100.21472382
112Sulfur relay system_Homo sapiens_hsa041220.20800224
113T cell receptor signaling pathway_Homo sapiens_hsa046600.19790788
114Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.19231913
115Prostate cancer_Homo sapiens_hsa052150.18700819
116NOD-like receptor signaling pathway_Homo sapiens_hsa046210.18663904
117Phototransduction_Homo sapiens_hsa047440.18544265
118Platelet activation_Homo sapiens_hsa046110.18323915
119Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.16683240
120Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.16389223
121Asthma_Homo sapiens_hsa053100.16197529
122Renal cell carcinoma_Homo sapiens_hsa052110.15856360
123Renin-angiotensin system_Homo sapiens_hsa046140.15585350
124Pyruvate metabolism_Homo sapiens_hsa006200.15236099
125Tight junction_Homo sapiens_hsa045300.15013862
126Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.15006152
127Huntingtons disease_Homo sapiens_hsa050160.14147842
128Peroxisome_Homo sapiens_hsa041460.13664287
129Central carbon metabolism in cancer_Homo sapiens_hsa052300.13110194
130Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.12967302
131Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.12945577
132beta-Alanine metabolism_Homo sapiens_hsa004100.10222317
133Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.09881079
134Tryptophan metabolism_Homo sapiens_hsa003800.09775317
135Olfactory transduction_Homo sapiens_hsa047400.09297638

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