DCTN6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene contains an RGD (Arg-Gly-Asp) motif in the N-terminal region, which confers adhesive properties to macromolecular proteins like fibronectin. It shares a high degree of sequence similarity with the mouse homolog, which has been suggested to play a role in mitochondrial biogenesis. The exact biological function of this gene is not known. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)7.23214392
2ATP synthesis coupled proton transport (GO:0015986)6.93691431
3energy coupled proton transport, down electrochemical gradient (GO:0015985)6.93691431
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)6.37291665
5respiratory electron transport chain (GO:0022904)5.63861179
6electron transport chain (GO:0022900)5.51543395
7chaperone-mediated protein transport (GO:0072321)5.00786944
8protein neddylation (GO:0045116)4.86817464
9protein complex biogenesis (GO:0070271)4.45763590
10mitochondrial respiratory chain complex I assembly (GO:0032981)4.39630694
11NADH dehydrogenase complex assembly (GO:0010257)4.39630694
12mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.39630694
13neuron cell-cell adhesion (GO:0007158)4.06023520
14mitochondrial respiratory chain complex assembly (GO:0033108)3.90795830
15hydrogen ion transmembrane transport (GO:1902600)3.79780471
16dopamine transport (GO:0015872)3.75031018
17sequestering of actin monomers (GO:0042989)3.74970566
18platelet dense granule organization (GO:0060155)3.69402749
19establishment of protein localization to mitochondrial membrane (GO:0090151)3.66948419
20pyrimidine nucleobase catabolic process (GO:0006208)3.60580603
21ATP biosynthetic process (GO:0006754)3.57613778
22response to pheromone (GO:0019236)3.56852124
23ATP hydrolysis coupled proton transport (GO:0015991)3.55308782
24energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.55308782
25organelle disassembly (GO:1903008)3.54395525
26ribonucleoprotein complex disassembly (GO:0032988)3.52168256
27purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.50926671
28presynaptic membrane assembly (GO:0097105)3.46623663
29proton transport (GO:0015992)3.43426323
30purine nucleoside triphosphate biosynthetic process (GO:0009145)3.41760896
31inner mitochondrial membrane organization (GO:0007007)3.39680430
32intraciliary transport (GO:0042073)3.39028307
33protein polyglutamylation (GO:0018095)3.34691257
34hydrogen transport (GO:0006818)3.34581324
35presynaptic membrane organization (GO:0097090)3.29088089
36GTP biosynthetic process (GO:0006183)3.27521798
37anterograde synaptic vesicle transport (GO:0048490)3.20785922
38respiratory chain complex IV assembly (GO:0008535)3.20415136
39regulation of catecholamine metabolic process (GO:0042069)3.18512501
40regulation of dopamine metabolic process (GO:0042053)3.18512501
41positive regulation of mitochondrial fission (GO:0090141)3.17972624
42DNA double-strand break processing (GO:0000729)3.17256332
43epithelial cilium movement (GO:0003351)3.14893469
44regulation of cilium movement (GO:0003352)3.13648436
45water-soluble vitamin biosynthetic process (GO:0042364)3.13090959
46synaptic transmission, dopaminergic (GO:0001963)3.10187861
47synaptic vesicle exocytosis (GO:0016079)3.06714795
48ribonucleoside triphosphate biosynthetic process (GO:0009201)3.06499505
49nucleobase catabolic process (GO:0046113)3.05693764
50transferrin transport (GO:0033572)3.02813841
51nonmotile primary cilium assembly (GO:0035058)3.02751802
52neuronal action potential propagation (GO:0019227)3.02374325
53central nervous system myelination (GO:0022010)3.01658170
54axon ensheathment in central nervous system (GO:0032291)3.01658170
55protein localization to synapse (GO:0035418)3.01207830
56cullin deneddylation (GO:0010388)2.95370551
57long-chain fatty acid biosynthetic process (GO:0042759)2.94473486
58cilium morphogenesis (GO:0060271)2.93686096
59negative regulation of synaptic transmission, GABAergic (GO:0032229)2.93330927
60cytochrome complex assembly (GO:0017004)2.91765487
61vocalization behavior (GO:0071625)2.90303545
62catecholamine transport (GO:0051937)2.89537078
63dopamine biosynthetic process (GO:0042416)2.89512149
64oxidative phosphorylation (GO:0006119)2.88703355
65nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.87871690
66gamma-aminobutyric acid signaling pathway (GO:0007214)2.87807635
67negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.86671054
68positive regulation of synapse assembly (GO:0051965)2.86575063
69behavioral response to nicotine (GO:0035095)2.85371195
70regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.83524133
71epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.83056192
72substantia nigra development (GO:0021762)2.82802392
73cholesterol biosynthetic process (GO:0006695)2.81627505
74neurotransmitter uptake (GO:0001504)2.81472442
75proteasome assembly (GO:0043248)2.79669601
76regulation of glutamate secretion (GO:0014048)2.78909317
77regulation of oxidative phosphorylation (GO:0002082)2.78807811
78intracellular protein transmembrane import (GO:0044743)2.78620575
79sterol biosynthetic process (GO:0016126)2.76048539
80GPI anchor metabolic process (GO:0006505)2.75259320
81exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.74759678
82ferric iron transport (GO:0015682)2.73069339
83trivalent inorganic cation transport (GO:0072512)2.73069339
84negative regulation of neurotransmitter transport (GO:0051589)2.72898284
85axoneme assembly (GO:0035082)2.71666427
86positive regulation of protein homodimerization activity (GO:0090073)2.70485957
87regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.70203153
88protein deneddylation (GO:0000338)2.69461322
89neuron-neuron synaptic transmission (GO:0007270)2.69411969
90anterograde axon cargo transport (GO:0008089)2.69089462
91postsynaptic membrane organization (GO:0001941)2.68823962
92mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.67238314
93positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.67238314
94aerobic respiration (GO:0009060)2.66168618
95retinal ganglion cell axon guidance (GO:0031290)2.66061544
96mannosylation (GO:0097502)2.65133425
97protein targeting to mitochondrion (GO:0006626)2.65085322
98neuron fate determination (GO:0048664)2.62892033
99calcium-mediated signaling using intracellular calcium source (GO:0035584)2.62603234
100protein K11-linked ubiquitination (GO:0070979)2.62208476
101L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.61204384
102isoprenoid biosynthetic process (GO:0008299)2.61010295
103behavioral response to cocaine (GO:0048148)2.59432864
104auditory behavior (GO:0031223)2.59246682
105establishment of protein localization to mitochondrion (GO:0072655)2.59149593
106nucleoside triphosphate biosynthetic process (GO:0009142)2.58928142
107protein localization to cilium (GO:0061512)2.57391990
108phagosome maturation (GO:0090382)2.57239500
109cilium organization (GO:0044782)2.57028869
110guanosine-containing compound biosynthetic process (GO:1901070)2.55854525
111cilium assembly (GO:0042384)2.55449744
112positive regulation of neurotransmitter secretion (GO:0001956)2.53158385
113regulation of protein kinase A signaling (GO:0010738)2.52877720
114ribosomal small subunit biogenesis (GO:0042274)2.52856895
115regulation of mitochondrial translation (GO:0070129)2.52591935
116mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.52294794
117UTP biosynthetic process (GO:0006228)2.52262607
118peptidyl-histidine modification (GO:0018202)2.51664257
119glutamate receptor signaling pathway (GO:0007215)2.49818735
120regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.49729471
121regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.49729471
122ubiquinone metabolic process (GO:0006743)2.49512933
123regulation of cell communication by electrical coupling (GO:0010649)2.49254170
124preassembly of GPI anchor in ER membrane (GO:0016254)2.48914113
125regulation of voltage-gated calcium channel activity (GO:1901385)2.46102917
126termination of RNA polymerase III transcription (GO:0006386)2.45682597
127transcription elongation from RNA polymerase III promoter (GO:0006385)2.45682597
128protein-cofactor linkage (GO:0018065)2.45151556
129gamma-aminobutyric acid transport (GO:0015812)2.44879981
130negative regulation of microtubule polymerization (GO:0031115)2.43327735
131regulation of synaptic vesicle exocytosis (GO:2000300)2.42901548
132positive regulation of neurotransmitter transport (GO:0051590)2.42634804
133cotranslational protein targeting to membrane (GO:0006613)2.41319791
134retinal cone cell development (GO:0046549)2.40750639
135cilium movement (GO:0003341)2.40744613
136transmission of nerve impulse (GO:0019226)2.40224746
137regulation of hexokinase activity (GO:1903299)2.39698270
138regulation of glucokinase activity (GO:0033131)2.39698270
139maturation of 5.8S rRNA (GO:0000460)2.39514109
140neuron recognition (GO:0008038)2.38983624
141viral transcription (GO:0019083)2.38963946
142DNA damage response, detection of DNA damage (GO:0042769)2.38277915
143GPI anchor biosynthetic process (GO:0006506)2.37304314
144viral protein processing (GO:0019082)2.36829668
145CTP metabolic process (GO:0046036)2.36344450
146CTP biosynthetic process (GO:0006241)2.36344450
147detection of calcium ion (GO:0005513)2.36304596
148C-terminal protein lipidation (GO:0006501)2.36278704
149protein localization to mitochondrion (GO:0070585)2.36248352
150C-terminal protein amino acid modification (GO:0018410)2.36128973
151C4-dicarboxylate transport (GO:0015740)2.35834280
152cellular ketone body metabolic process (GO:0046950)2.34567252
153photoreceptor cell development (GO:0042461)2.32043320
154regulation of feeding behavior (GO:0060259)2.31489741
1557-methylguanosine mRNA capping (GO:0006370)2.30670190
156ubiquinone biosynthetic process (GO:0006744)2.28497266
157inner ear receptor stereocilium organization (GO:0060122)2.27859528
158DNA integration (GO:0015074)2.27172461
159negative regulation of transcription regulatory region DNA binding (GO:2000678)2.25734208
160RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.25643899
161tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.25643899
162pyrimidine dimer repair (GO:0006290)2.25441974

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.14656313
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.42650722
3GBX2_23144817_ChIP-Seq_PC3_Human3.39754513
4TAF15_26573619_Chip-Seq_HEK293_Human3.04828206
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.43159760
6ZFP57_27257070_Chip-Seq_ESCs_Mouse2.42593727
7TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.41929692
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.40600319
9GABP_17652178_ChIP-ChIP_JURKAT_Human2.37911891
10CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.37819834
11JARID2_20064375_ChIP-Seq_MESCs_Mouse2.34660328
12VDR_22108803_ChIP-Seq_LS180_Human2.30073755
13SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.25922879
14FUS_26573619_Chip-Seq_HEK293_Human2.11895381
15BMI1_23680149_ChIP-Seq_NPCS_Mouse2.10818916
16NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.06876921
17* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.02713969
18EZH2_27304074_Chip-Seq_ESCs_Mouse2.02052206
19SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.01888923
20EST1_17652178_ChIP-ChIP_JURKAT_Human2.01011896
21CTBP1_25329375_ChIP-Seq_LNCAP_Human1.99601990
22POU3F2_20337985_ChIP-ChIP_501MEL_Human1.99027611
23CTBP2_25329375_ChIP-Seq_LNCAP_Human1.98575658
24SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.97003999
25JARID2_20075857_ChIP-Seq_MESCs_Mouse1.86441822
26SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.86086975
27VDR_23849224_ChIP-Seq_CD4+_Human1.86017088
28P300_19829295_ChIP-Seq_ESCs_Human1.79929484
29EED_16625203_ChIP-ChIP_MESCs_Mouse1.79495734
30GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.78842794
31BP1_19119308_ChIP-ChIP_Hs578T_Human1.75815407
32HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.72290392
33JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.70897398
34NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.67833054
35EZH2_18974828_ChIP-Seq_MESCs_Mouse1.67048738
36RNF2_18974828_ChIP-Seq_MESCs_Mouse1.67048738
37REST_21632747_ChIP-Seq_MESCs_Mouse1.66948502
38MTF2_20144788_ChIP-Seq_MESCs_Mouse1.65311420
39SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.60635070
40IKZF1_21737484_ChIP-ChIP_HCT116_Human1.59069628
41MYC_18940864_ChIP-ChIP_HL60_Human1.58422717
42E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.57881707
43PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.57612742
44ER_23166858_ChIP-Seq_MCF-7_Human1.56474455
45CBX2_27304074_Chip-Seq_ESCs_Mouse1.55257502
46PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.54843484
47SUZ12_27294783_Chip-Seq_ESCs_Mouse1.54431620
48PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.49998410
49SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.49898237
50AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.48715068
51* MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.48023847
52OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.46882039
53FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.45602206
54IGF1R_20145208_ChIP-Seq_DFB_Human1.45577106
55CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.45054072
56EZH2_27294783_Chip-Seq_ESCs_Mouse1.43381256
57REST_18959480_ChIP-ChIP_MESCs_Mouse1.42743284
58TOP2B_26459242_ChIP-Seq_MCF-7_Human1.41578212
59ETS1_20019798_ChIP-Seq_JURKAT_Human1.39840237
60EWS_26573619_Chip-Seq_HEK293_Human1.38727028
61RNF2_27304074_Chip-Seq_NSC_Mouse1.37448242
62UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.36209514
63PADI4_21655091_ChIP-ChIP_MCF-7_Human1.35814886
64TP53_22573176_ChIP-Seq_HFKS_Human1.33301179
65SMAD4_21799915_ChIP-Seq_A2780_Human1.33214799
66* SRF_21415370_ChIP-Seq_HL-1_Mouse1.31833024
67FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.28261801
68* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.28069217
69IRF1_19129219_ChIP-ChIP_H3396_Human1.27592046
70IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.26532891
71CBP_20019798_ChIP-Seq_JUKART_Human1.26532891
72SALL1_21062744_ChIP-ChIP_HESCs_Human1.25578728
73ELF1_17652178_ChIP-ChIP_JURKAT_Human1.25203206
74ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.25188162
75SUZ12_27294783_Chip-Seq_NPCs_Mouse1.23344185
76MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.23202420
77THAP11_20581084_ChIP-Seq_MESCs_Mouse1.22062932
78CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.21950787
79EZH2_27294783_Chip-Seq_NPCs_Mouse1.21577180
80EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.21357750
81* SOX2_19829295_ChIP-Seq_ESCs_Human1.21254958
82PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.20853880
83PCGF2_27294783_Chip-Seq_ESCs_Mouse1.18402717
84TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.17768111
85JUN_21703547_ChIP-Seq_K562_Human1.17702709
86CREB1_15753290_ChIP-ChIP_HEK293T_Human1.17562902
87RNF2_27304074_Chip-Seq_ESCs_Mouse1.16208604
88GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.14253116
89FLI1_27457419_Chip-Seq_LIVER_Mouse1.13759063
90* SMAD3_21741376_ChIP-Seq_EPCs_Human1.12320235
91PRDM14_20953172_ChIP-Seq_ESCs_Human1.11770862
92* FOXP3_21729870_ChIP-Seq_TREG_Human1.10451949
93AR_21572438_ChIP-Seq_LNCaP_Human1.08237407
94FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.07736444
95ELK1_19687146_ChIP-ChIP_HELA_Human1.06808655
96GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.05830707
97PCGF2_27294783_Chip-Seq_NPCs_Mouse1.05689866
98NFE2_27457419_Chip-Seq_LIVER_Mouse1.05354315
99STAT3_23295773_ChIP-Seq_U87_Human1.05340083
100POU5F1_16153702_ChIP-ChIP_HESCs_Human1.04831069
101TCF4_22108803_ChIP-Seq_LS180_Human1.04221871
102HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.03321976
103KLF5_20875108_ChIP-Seq_MESCs_Mouse1.02984006
104NR3C1_21868756_ChIP-Seq_MCF10A_Human1.02879926
105BCAT_22108803_ChIP-Seq_LS180_Human1.02586354
106CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.02102888
107NR3C1_23031785_ChIP-Seq_PC12_Mouse1.01465884
108NANOG_18555785_Chip-Seq_ESCs_Mouse0.99813447
109HTT_18923047_ChIP-ChIP_STHdh_Human0.99739977
110RUNX2_22187159_ChIP-Seq_PCA_Human0.98981547
111CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.97567571
112FOXA1_27270436_Chip-Seq_PROSTATE_Human0.97159301
113FOXA1_25329375_ChIP-Seq_VCAP_Human0.97159301
114SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.96396279
115RARB_27405468_Chip-Seq_BRAIN_Mouse0.96342274
116ELK1_22589737_ChIP-Seq_MCF10A_Human0.96311739
117TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.95331663
118STAT3_18555785_Chip-Seq_ESCs_Mouse0.95292014
119E2F1_18555785_Chip-Seq_ESCs_Mouse0.94836163
120RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.94364343
121TAL1_26923725_Chip-Seq_HPCs_Mouse0.93686395
122PIAS1_25552417_ChIP-Seq_VCAP_Human0.93238657
123AR_25329375_ChIP-Seq_VCAP_Human0.93231485
124CRX_20693478_ChIP-Seq_RETINA_Mouse0.93037535
125SUZ12_18555785_Chip-Seq_ESCs_Mouse0.92995802
126ZNF274_21170338_ChIP-Seq_K562_Hela0.92932152
127DCP1A_22483619_ChIP-Seq_HELA_Human0.92907253
128EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.92862001
129RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.91691535
130CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.91608448
131EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.91557925
132REST_19997604_ChIP-ChIP_NEURONS_Mouse0.90602393
133CDX2_19796622_ChIP-Seq_MESCs_Mouse0.89128957
134* SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.88251805
135P53_22387025_ChIP-Seq_ESCs_Mouse0.87858540
136PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.86667583
137* NANOG_19829295_ChIP-Seq_ESCs_Human0.86381283

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.27172991
2MP0001529_abnormal_vocalization3.76631464
3MP0001905_abnormal_dopamine_level3.12300836
4MP0001968_abnormal_touch/_nociception3.01987472
5MP0004859_abnormal_synaptic_plasticity2.96806489
6MP0002736_abnormal_nociception_after2.86712629
7MP0009745_abnormal_behavioral_response2.78541606
8MP0003635_abnormal_synaptic_transmissio2.72709804
9MP0006276_abnormal_autonomic_nervous2.72123299
10MP0003011_delayed_dark_adaptation2.57187112
11MP0002102_abnormal_ear_morphology2.53013779
12MP0002064_seizures2.52593546
13MP0002837_dystrophic_cardiac_calcinosis2.50538304
14MP0002272_abnormal_nervous_system2.46603867
15MP0002822_catalepsy2.43114081
16MP0002735_abnormal_chemical_nociception2.36286872
17MP0009046_muscle_twitch2.36237273
18MP0004270_analgesia2.32097121
19MP0002572_abnormal_emotion/affect_behav2.29545317
20MP0002734_abnormal_mechanical_nocicepti2.21928912
21MP0002063_abnormal_learning/memory/cond2.18361056
22MP0001440_abnormal_grooming_behavior2.12968103
23MP0001970_abnormal_pain_threshold2.00726503
24MP0009379_abnormal_foot_pigmentation2.00642940
25MP0004133_heterotaxia1.95273644
26MP0005253_abnormal_eye_physiology1.94913774
27MP0004142_abnormal_muscle_tone1.90920419
28MP0001486_abnormal_startle_reflex1.86892692
29MP0002733_abnormal_thermal_nociception1.85003020
30MP0001501_abnormal_sleep_pattern1.78987416
31MP0002067_abnormal_sensory_capabilities1.74598606
32MP0008877_abnormal_DNA_methylation1.69822017
33MP0001188_hyperpigmentation1.66762608
34MP0001984_abnormal_olfaction1.65234615
35MP0010386_abnormal_urinary_bladder1.61867466
36MP0004924_abnormal_behavior1.61683932
37MP0005386_behavior/neurological_phenoty1.61683932
38MP0002638_abnormal_pupillary_reflex1.61026121
39MP0008995_early_reproductive_senescence1.60358749
40MP0002938_white_spotting1.58960643
41MP0002184_abnormal_innervation1.52995559
42MP0005423_abnormal_somatic_nervous1.52139900
43MP0005187_abnormal_penis_morphology1.51433299
44MP0000751_myopathy1.51273154
45MP0004147_increased_porphyrin_level1.51212441
46MP0008058_abnormal_DNA_repair1.51009716
47MP0003122_maternal_imprinting1.50649794
48MP0003121_genomic_imprinting1.49649214
49MP0005645_abnormal_hypothalamus_physiol1.48934354
50MP0000372_irregular_coat_pigmentation1.45700583
51MP0000778_abnormal_nervous_system1.43249770
52MP0005171_absent_coat_pigmentation1.39351612
53MP0005409_darkened_coat_color1.38906290
54MP0002163_abnormal_gland_morphology1.38471395
55MP0003186_abnormal_redox_activity1.38256603
56MP0004215_abnormal_myocardial_fiber1.37793165
57MP0001986_abnormal_taste_sensitivity1.37346010
58MP0004742_abnormal_vestibular_system1.34574359
59MP0002909_abnormal_adrenal_gland1.27208824
60MP0002928_abnormal_bile_duct1.27013215
61MP0002557_abnormal_social/conspecific_i1.26387474
62MP0000920_abnormal_myelination1.25572497
63MP0008875_abnormal_xenobiotic_pharmacok1.22756751
64MP0003136_yellow_coat_color1.21462408
65MP0003195_calcinosis1.19684910
66MP0004036_abnormal_muscle_relaxation1.19179052
67MP0000647_abnormal_sebaceous_gland1.18287466
68MP0002653_abnormal_ependyma_morphology1.17944085
69MP0004885_abnormal_endolymph1.17358857
70MP0004484_altered_response_of1.14958715
71MP0006036_abnormal_mitochondrial_physio1.13382185
72MP0005551_abnormal_eye_electrophysiolog1.12135551
73MP0003879_abnormal_hair_cell1.10648413
74MP0005379_endocrine/exocrine_gland_phen1.10130467
75MP0008569_lethality_at_weaning1.09767615
76MP0004145_abnormal_muscle_electrophysio1.07104386
77MP0002066_abnormal_motor_capabilities/c1.07086684
78MP0001664_abnormal_digestion1.06874936
79MP0000749_muscle_degeneration1.06660888
80MP0006035_abnormal_mitochondrial_morpho1.05558582
81MP0002882_abnormal_neuron_morphology1.05203155
82MP0002234_abnormal_pharynx_morphology1.05084475
83MP0000013_abnormal_adipose_tissue1.02330082
84MP0003329_amyloid_beta_deposits1.02256130
85MP0002160_abnormal_reproductive_system0.99636091
86MP0002876_abnormal_thyroid_physiology0.98741512
87MP0005195_abnormal_posterior_eye0.97144701
88MP0000569_abnormal_digit_pigmentation0.95227317
89MP0000427_abnormal_hair_cycle0.94841950
90MP0005646_abnormal_pituitary_gland0.94523809
91MP0002229_neurodegeneration0.94176068
92MP0001764_abnormal_homeostasis0.93682761
93MP0004085_abnormal_heartbeat0.93196809
94MP0004811_abnormal_neuron_physiology0.92668882
95MP0005389_reproductive_system_phenotype0.91760045
96MP0005391_vision/eye_phenotype0.91025463
97MP0000955_abnormal_spinal_cord0.90174787
98MP0001963_abnormal_hearing_physiology0.89365169
99MP0001502_abnormal_circadian_rhythm0.88366819
100MP0002090_abnormal_vision0.86828264
101MP0005248_abnormal_Harderian_gland0.86678707
102MP0000639_abnormal_adrenal_gland0.84706781
103MP0003718_maternal_effect0.84106668
104MP0001293_anophthalmia0.83275098
105MP0002752_abnormal_somatic_nervous0.82083672
106MP0002751_abnormal_autonomic_nervous0.82050335
107MP0006072_abnormal_retinal_apoptosis0.81478301
108MP0003786_premature_aging0.81387779
109MP0006054_spinal_hemorrhage0.81038617
110MP0003937_abnormal_limbs/digits/tail_de0.80721280
111MP0008872_abnormal_physiological_respon0.79767888
112MP0003646_muscle_fatigue0.75979068
113MP0003633_abnormal_nervous_system0.75461046
114MP0000631_abnormal_neuroendocrine_gland0.75139181
115MP0001485_abnormal_pinna_reflex0.74016620
116MP0008789_abnormal_olfactory_epithelium0.73423234
117MP0005394_taste/olfaction_phenotype0.72820151
118MP0005499_abnormal_olfactory_system0.72820151
119MP0005410_abnormal_fertilization0.72342494
120MP0009697_abnormal_copulation0.71727737
121MP0002332_abnormal_exercise_endurance0.70893166
122MP0003631_nervous_system_phenotype0.69263238
123MP0005084_abnormal_gallbladder_morpholo0.68791271
124MP0003787_abnormal_imprinting0.66955075
125MP0003137_abnormal_impulse_conducting0.66494958
126MP0000026_abnormal_inner_ear0.64773344
127MP0005671_abnormal_response_to0.64716211
128MP0003634_abnormal_glial_cell0.63059066
129MP0003183_abnormal_peptide_metabolism0.62773420
130MP0008874_decreased_physiological_sensi0.62085184
131MP0000015_abnormal_ear_pigmentation0.61866028
132MP0005535_abnormal_body_temperature0.60921583
133MP0004084_abnormal_cardiac_muscle0.60354264
134MP0006292_abnormal_olfactory_placode0.60073644

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)6.77165280
2Abnormal mitochondria in muscle tissue (HP:0008316)6.10913464
3Mitochondrial inheritance (HP:0001427)5.80166733
4Progressive macrocephaly (HP:0004481)5.69547398
5Acute encephalopathy (HP:0006846)5.13394095
6Increased CSF lactate (HP:0002490)4.76372087
7Hepatocellular necrosis (HP:0001404)4.73058013
8Focal motor seizures (HP:0011153)4.29761335
9Increased hepatocellular lipid droplets (HP:0006565)4.26713101
10Renal Fanconi syndrome (HP:0001994)3.83980695
11Increased serum pyruvate (HP:0003542)3.83130617
12Abnormality of glycolysis (HP:0004366)3.83130617
13Hepatic necrosis (HP:0002605)3.74801234
14Optic disc pallor (HP:0000543)3.69753121
15True hermaphroditism (HP:0010459)3.68239635
16Lipid accumulation in hepatocytes (HP:0006561)3.62579707
17Pancreatic fibrosis (HP:0100732)3.60677874
18Hypothermia (HP:0002045)3.44454354
19Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.41702856
20Exercise intolerance (HP:0003546)3.41079226
21Leukodystrophy (HP:0002415)3.40779566
22Pancreatic cysts (HP:0001737)3.37381643
23Neuroendocrine neoplasm (HP:0100634)3.35043353
243-Methylglutaconic aciduria (HP:0003535)3.33761774
25Increased intramyocellular lipid droplets (HP:0012240)3.27922996
26Respiratory failure (HP:0002878)3.25664583
27Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.24081614
28Myokymia (HP:0002411)3.20548484
29Atonic seizures (HP:0010819)3.17869976
30Cerebral edema (HP:0002181)3.11532451
31Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.08927296
32Epileptic encephalopathy (HP:0200134)3.06741434
33Lactic acidosis (HP:0003128)3.03868783
34Pheochromocytoma (HP:0002666)3.02393951
35Abnormality of midbrain morphology (HP:0002418)3.01535993
36Molar tooth sign on MRI (HP:0002419)3.01535993
37Nephronophthisis (HP:0000090)3.00632118
38Abnormal hair whorl (HP:0010721)2.87667151
39Hyperventilation (HP:0002883)2.72044253
40Increased serum lactate (HP:0002151)2.71654811
41Retinal dysplasia (HP:0007973)2.71282526
42Exertional dyspnea (HP:0002875)2.70082183
43Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.66060704
44Decreased activity of mitochondrial respiratory chain (HP:0008972)2.66060704
45Renal cortical cysts (HP:0000803)2.65043316
46Abnormality of cells of the erythroid lineage (HP:0012130)2.63749715
47Respiratory difficulties (HP:0002880)2.62706980
48Short tibia (HP:0005736)2.59146828
49Limb dystonia (HP:0002451)2.57825990
50Increased muscle lipid content (HP:0009058)2.57592352
51Focal seizures (HP:0007359)2.55949801
52X-linked dominant inheritance (HP:0001423)2.55884984
53Parakeratosis (HP:0001036)2.51377835
54Medial flaring of the eyebrow (HP:0010747)2.47504635
55Abnormality of the labia minora (HP:0012880)2.46199311
56Abnormality of renal resorption (HP:0011038)2.44747638
57Absence seizures (HP:0002121)2.43631077
58Abnormal number of erythroid precursors (HP:0012131)2.41602199
59Abnormality of the renal medulla (HP:0100957)2.39800651
60Aplasia/Hypoplasia of the tongue (HP:0010295)2.37838264
61Methylmalonic acidemia (HP:0002912)2.37145971
62Dialeptic seizures (HP:0011146)2.37075495
63Gait imbalance (HP:0002141)2.29505477
64Sensory axonal neuropathy (HP:0003390)2.29365462
65Abnormality of the renal cortex (HP:0011035)2.29065916
66Febrile seizures (HP:0002373)2.27245678
67Sclerocornea (HP:0000647)2.26009544
68Anxiety (HP:0000739)2.24237986
69Poor suck (HP:0002033)2.18181461
70Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.14662363
71Degeneration of the lateral corticospinal tracts (HP:0002314)2.14662363
72Congenital primary aphakia (HP:0007707)2.13206629
73Visual hallucinations (HP:0002367)2.12817292
74Abnormal pupillary function (HP:0007686)2.12082998
75Microvesicular hepatic steatosis (HP:0001414)2.10999932
76Nephrogenic diabetes insipidus (HP:0009806)2.10851700
77Occipital encephalocele (HP:0002085)2.08503946
78Hyperglycinemia (HP:0002154)2.08180317
79Emotional lability (HP:0000712)2.07121607
80Broad-based gait (HP:0002136)2.06958029
81Progressive inability to walk (HP:0002505)2.06189886
82Colon cancer (HP:0003003)2.05166600
83Postaxial hand polydactyly (HP:0001162)2.04651371
84Methylmalonic aciduria (HP:0012120)2.04484946
85Amblyopia (HP:0000646)2.03607709
86Absent/shortened dynein arms (HP:0200106)2.02109259
87Dynein arm defect of respiratory motile cilia (HP:0012255)2.02109259
88Delusions (HP:0000746)2.01779701
89Lissencephaly (HP:0001339)2.00712352
90Abnormal ciliary motility (HP:0012262)1.98831500
91Muscle hypertrophy of the lower extremities (HP:0008968)1.98771282
92Anencephaly (HP:0002323)1.98233401
93Chronic hepatic failure (HP:0100626)1.97985898
94Genital tract atresia (HP:0001827)1.96721196
95Intestinal atresia (HP:0011100)1.96482331
96Specific learning disability (HP:0001328)1.96056348
97Hemiparesis (HP:0001269)1.95077986
98Degeneration of anterior horn cells (HP:0002398)1.95011843
99Abnormality of the anterior horn cell (HP:0006802)1.95011843
100Vaginal atresia (HP:0000148)1.94734342
101Postaxial foot polydactyly (HP:0001830)1.93735967
102Male pseudohermaphroditism (HP:0000037)1.91843700
103Congenital ichthyosiform erythroderma (HP:0007431)1.90702956
104Thyroid-stimulating hormone excess (HP:0002925)1.90610539
105Cerebral hemorrhage (HP:0001342)1.90550203
106Generalized tonic-clonic seizures (HP:0002069)1.90233103
107Congenital stationary night blindness (HP:0007642)1.88356126
108Hypoglycemic coma (HP:0001325)1.88119422
109Generalized aminoaciduria (HP:0002909)1.87429699
110Abnormal respiratory motile cilium morphology (HP:0005938)1.85647963
111Abnormal respiratory epithelium morphology (HP:0012253)1.85647963
112Decreased testicular size (HP:0008734)1.84276492
113Cystic liver disease (HP:0006706)1.83840218
114Oligodactyly (hands) (HP:0001180)1.83369427
115Neonatal respiratory distress (HP:0002643)1.81445935
116Furrowed tongue (HP:0000221)1.80612751
117Abnormality of macular pigmentation (HP:0008002)1.79767874
118Calf muscle hypertrophy (HP:0008981)1.79433612
119Optic nerve hypoplasia (HP:0000609)1.79372511
120Pachygyria (HP:0001302)1.78764736
121Esotropia (HP:0000565)1.78438653
122CNS demyelination (HP:0007305)1.78108951
123Inability to walk (HP:0002540)1.77932645
124Lethargy (HP:0001254)1.75652552
125Congenital hepatic fibrosis (HP:0002612)1.75404661
126Type II lissencephaly (HP:0007260)1.73617040
127Muscular hypotonia of the trunk (HP:0008936)1.71752247
128Abnormality of urine glucose concentration (HP:0011016)1.71628243
129Glycosuria (HP:0003076)1.71628243
130Atrophy/Degeneration involving motor neurons (HP:0007373)1.71510115
131Polyphagia (HP:0002591)1.68791400
132Abnormality of alanine metabolism (HP:0010916)1.67028849
133Hyperalaninemia (HP:0003348)1.67028849
134Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.67028849
135Progressive cerebellar ataxia (HP:0002073)1.66483930
136Cerebral hypomyelination (HP:0006808)1.65809275
137Abnormality of the vocal cords (HP:0008777)1.64475496
138Aplasia/Hypoplasia of the brainstem (HP:0007362)1.63501399
139Hypoplasia of the brainstem (HP:0002365)1.63501399
140Respiratory insufficiency due to muscle weakness (HP:0002747)1.61979083
141Abnormal respiratory motile cilium physiology (HP:0012261)1.61030759
142Neurofibrillary tangles (HP:0002185)1.60339199
143Myotonia (HP:0002486)1.59719412
144Abnormal autonomic nervous system physiology (HP:0012332)1.57174919
145Hypoplastic left heart (HP:0004383)1.57061107
146Psychosis (HP:0000709)1.56489108
147Aplasia/Hypoplasia of the tibia (HP:0005772)1.55629539

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K124.30838951
2CASK3.88814950
3MAP4K23.24059490
4ERBB32.83570873
5ARAF2.76301901
6MAP2K72.53653392
7NME12.52432600
8TRIM282.45991467
9STK162.45771322
10MYLK2.41490988
11TNIK2.22179616
12PNCK2.07432679
13CDK191.98401423
14FRK1.97305860
15NTRK31.95546635
16EPHA41.94616227
17GRK71.90667411
18PINK11.88480436
19STK391.88202104
20MAPKAPK51.82063038
21MST41.81404969
22RIPK41.80805370
23NME21.73003838
24OXSR11.64354851
25GRK51.62864617
26MUSK1.62073550
27MAP3K41.59958108
28SIK31.58596065
29PLK21.55716537
30SRPK11.54029088
31LIMK11.49384718
32MINK11.46072006
33DYRK31.45344641
34ADRBK21.43247905
35NEK11.40299735
36BCR1.40146314
37PAK31.38185723
38BCKDK1.34503173
39MAPK131.33376124
40EPHA31.27809342
41BMPR1B1.26421806
42ZAK1.26400658
43MAP3K91.22151901
44MKNK21.20882704
45MKNK11.20092725
46CAMK2B1.19361443
47CAMK2A1.14972989
48BMPR21.13928841
49MARK11.11870822
50VRK11.11792998
51DAPK11.07997067
52GRK11.05230688
53PTK2B1.03214541
54UHMK11.02412624
55NUAK11.01286020
56PLK30.96890451
57MAP3K130.93862285
58MAP2K40.93508405
59CAMK2D0.91848204
60PIM20.90456856
61INSRR0.88744927
62FGR0.87010786
63WNK40.86845847
64CSNK1G30.86765189
65WEE10.86593605
66PRKCE0.85244011
67RPS6KA40.84174399
68VRK20.83518192
69FES0.81999996
70TXK0.81604418
71BRAF0.81034316
72ADRBK10.79083488
73PDK20.78879582
74CDK50.78574402
75PLK40.77230155
76CCNB10.76926895
77PRKCG0.76690195
78PIK3CG0.76540773
79NTRK20.76309647
80ROCK20.75772217
81DYRK20.74855317
82CDK140.74397085
83CDK180.74339655
84RAF10.74196461
85CSNK1G20.71476561
86PRPF4B0.71178135
87TESK10.70239240
88TLK10.70045383
89BRSK20.68626215
90DAPK20.68546981
91DAPK30.68146000
92ILK0.67366665
93OBSCN0.66854917
94PIK3CA0.66798655
95CDK150.66526735
96RPS6KA50.65705655
97NTRK10.65642092
98TSSK60.65541586
99CAMK2G0.65251609
100CDK11A0.64915058
101PKN10.62338654
102CDK30.62111319
103SYK0.60893130
104CAMK10.60176237
105YES10.59763527
106PBK0.59391630
107PLK10.58255611
108EIF2AK30.58202994
109CAMKK20.57927661
110TEC0.56926416
111FER0.54544312
112DYRK1A0.53588172
113PHKG10.50210737
114PHKG20.50210737
115TIE10.49532219
116PRKCQ0.48409817
117GRK60.47906425
118PRKACA0.47484620
119WNK30.46227734
120CSNK1A10.44797164
121MAP3K60.43328155
122KSR10.42298521
123PAK60.41883578
124PRKD30.41596153
125PDK40.41305065
126PDK30.41305065
127EIF2AK10.40455484
128STK38L0.40187442
129CDK80.39938832
130CSNK2A10.38866652
131MAPK150.38420446
132ACVR1B0.37915099
133FLT30.37904145
134TGFBR10.37597241
135CSNK1G10.37479994
136BUB10.37165572
137CSNK1A1L0.36349335
138TNK20.35524075
139MAPK40.34262454
140EPHB20.33965040

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001905.55347744
2Parkinsons disease_Homo sapiens_hsa050124.70316614
3Alzheimers disease_Homo sapiens_hsa050103.72807106
4Huntingtons disease_Homo sapiens_hsa050163.22998203
5Collecting duct acid secretion_Homo sapiens_hsa049662.76540509
6Proteasome_Homo sapiens_hsa030502.70899955
7Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.68180893
8Ribosome_Homo sapiens_hsa030102.60068918
9Nicotine addiction_Homo sapiens_hsa050332.54253146
10Cardiac muscle contraction_Homo sapiens_hsa042602.50911667
11Protein export_Homo sapiens_hsa030602.31587085
12Synaptic vesicle cycle_Homo sapiens_hsa047212.15944626
13Butanoate metabolism_Homo sapiens_hsa006501.95487470
14Vibrio cholerae infection_Homo sapiens_hsa051101.87652446
15Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.85005094
16Propanoate metabolism_Homo sapiens_hsa006401.82452661
17Serotonergic synapse_Homo sapiens_hsa047261.69238879
18RNA polymerase_Homo sapiens_hsa030201.66165833
19Morphine addiction_Homo sapiens_hsa050321.55022937
20Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.53839777
21Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.53053982
22GABAergic synapse_Homo sapiens_hsa047271.50141875
23Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.48902851
24SNARE interactions in vesicular transport_Homo sapiens_hsa041301.46292167
25Olfactory transduction_Homo sapiens_hsa047401.40275718
26Amphetamine addiction_Homo sapiens_hsa050311.38520711
27Circadian entrainment_Homo sapiens_hsa047131.37726451
28Glutamatergic synapse_Homo sapiens_hsa047241.34145668
29Taste transduction_Homo sapiens_hsa047421.32592344
30Peroxisome_Homo sapiens_hsa041461.29896493
31Dopaminergic synapse_Homo sapiens_hsa047281.29892281
32Rheumatoid arthritis_Homo sapiens_hsa053231.28286377
33Phototransduction_Homo sapiens_hsa047441.27946236
34Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.26901872
35Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.23046374
36Folate biosynthesis_Homo sapiens_hsa007901.22036575
37Long-term potentiation_Homo sapiens_hsa047201.19428235
38Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.18496202
39Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.13549966
40Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.13133611
41Primary bile acid biosynthesis_Homo sapiens_hsa001201.10614764
42Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.09806095
43Cocaine addiction_Homo sapiens_hsa050301.07935014
44Circadian rhythm_Homo sapiens_hsa047101.07599720
45Long-term depression_Homo sapiens_hsa047301.06532896
46Nitrogen metabolism_Homo sapiens_hsa009101.06268570
47Homologous recombination_Homo sapiens_hsa034401.04593771
48Fanconi anemia pathway_Homo sapiens_hsa034601.02880541
49Selenocompound metabolism_Homo sapiens_hsa004501.02522457
50Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.01471053
51Renin secretion_Homo sapiens_hsa049240.98964546
52Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.97482944
53Calcium signaling pathway_Homo sapiens_hsa040200.96246696
54Fatty acid elongation_Homo sapiens_hsa000620.95574652
55Cholinergic synapse_Homo sapiens_hsa047250.95369405
56Tryptophan metabolism_Homo sapiens_hsa003800.94708287
57Salivary secretion_Homo sapiens_hsa049700.90840536
58Maturity onset diabetes of the young_Homo sapiens_hsa049500.90806613
59Fatty acid metabolism_Homo sapiens_hsa012120.86630892
60Phagosome_Homo sapiens_hsa041450.86529332
61Non-homologous end-joining_Homo sapiens_hsa034500.86259263
62* Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.83282609
63Mismatch repair_Homo sapiens_hsa034300.82819882
64alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.79851134
65Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.79703597
66Ether lipid metabolism_Homo sapiens_hsa005650.73976708
67Oxytocin signaling pathway_Homo sapiens_hsa049210.73814812
68Cysteine and methionine metabolism_Homo sapiens_hsa002700.72784881
69Vitamin B6 metabolism_Homo sapiens_hsa007500.71531860
70Gastric acid secretion_Homo sapiens_hsa049710.68661903
71Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.66070418
72Oocyte meiosis_Homo sapiens_hsa041140.64584339
73Glutathione metabolism_Homo sapiens_hsa004800.62996636
74Insulin secretion_Homo sapiens_hsa049110.62978682
75RNA transport_Homo sapiens_hsa030130.62043687
76Purine metabolism_Homo sapiens_hsa002300.61575863
77Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.61448683
78Vascular smooth muscle contraction_Homo sapiens_hsa042700.59845475
79Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.59005746
80Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.58325607
81Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.58176466
82Gap junction_Homo sapiens_hsa045400.57935323
83Regulation of autophagy_Homo sapiens_hsa041400.56351040
84Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.56227785
85Axon guidance_Homo sapiens_hsa043600.55739624
86Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.55262585
87Autoimmune thyroid disease_Homo sapiens_hsa053200.55066559
88Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.54610397
89Sphingolipid metabolism_Homo sapiens_hsa006000.54474531
90beta-Alanine metabolism_Homo sapiens_hsa004100.53770458
91Sulfur relay system_Homo sapiens_hsa041220.53290628
92Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.52138713
93Basal transcription factors_Homo sapiens_hsa030220.51011947
94Pyrimidine metabolism_Homo sapiens_hsa002400.50900447
95Steroid hormone biosynthesis_Homo sapiens_hsa001400.50848105
96Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.49906030
97Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.49511574
98Allograft rejection_Homo sapiens_hsa053300.49398239
99Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.49360343
100Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.49036312
101Base excision repair_Homo sapiens_hsa034100.48663294
102Chemical carcinogenesis_Homo sapiens_hsa052040.48574878
103Arginine and proline metabolism_Homo sapiens_hsa003300.47322436
104Pyruvate metabolism_Homo sapiens_hsa006200.47111747
105Type I diabetes mellitus_Homo sapiens_hsa049400.46534029
1062-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.46348498
107Alcoholism_Homo sapiens_hsa050340.45671194
108Asthma_Homo sapiens_hsa053100.44953633
109Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.44579708
110Graft-versus-host disease_Homo sapiens_hsa053320.43591303
111Dilated cardiomyopathy_Homo sapiens_hsa054140.43273559
112Carbon metabolism_Homo sapiens_hsa012000.42491852
113Sulfur metabolism_Homo sapiens_hsa009200.42457158
114One carbon pool by folate_Homo sapiens_hsa006700.41912095
115Metabolic pathways_Homo sapiens_hsa011000.41858457
116Fatty acid degradation_Homo sapiens_hsa000710.41136503
117Pentose and glucuronate interconversions_Homo sapiens_hsa000400.40235788
118Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.39639000
119Retinol metabolism_Homo sapiens_hsa008300.39453896
120cAMP signaling pathway_Homo sapiens_hsa040240.39243316
121Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.38566128
122Aldosterone synthesis and secretion_Homo sapiens_hsa049250.38393772
123Caffeine metabolism_Homo sapiens_hsa002320.38058330
124African trypanosomiasis_Homo sapiens_hsa051430.38017045
125GnRH signaling pathway_Homo sapiens_hsa049120.37985125
126Arachidonic acid metabolism_Homo sapiens_hsa005900.36331259
127cGMP-PKG signaling pathway_Homo sapiens_hsa040220.36300692
128Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.35521566
129Steroid biosynthesis_Homo sapiens_hsa001000.34530137
130Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.33808240
131Ras signaling pathway_Homo sapiens_hsa040140.31403866
132Sphingolipid signaling pathway_Homo sapiens_hsa040710.30360675
133Pancreatic secretion_Homo sapiens_hsa049720.26483999
134Nucleotide excision repair_Homo sapiens_hsa034200.25624170
135Melanogenesis_Homo sapiens_hsa049160.24899260
136RNA degradation_Homo sapiens_hsa030180.18171267
137Tyrosine metabolism_Homo sapiens_hsa003500.17117703
138Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.17098651
139Primary immunodeficiency_Homo sapiens_hsa053400.16976464
140Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.16593976
141Hematopoietic cell lineage_Homo sapiens_hsa046400.16168662
142Salmonella infection_Homo sapiens_hsa051320.16051721
143Linoleic acid metabolism_Homo sapiens_hsa005910.15331887
144MAPK signaling pathway_Homo sapiens_hsa040100.15329159
145Spliceosome_Homo sapiens_hsa030400.14200359
146Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.13498457

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »