DAPP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.79869824
2neutrophil activation involved in immune response (GO:0002283)6.78702468
3definitive hemopoiesis (GO:0060216)5.11611067
4antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.01631110
5viral transcription (GO:0019083)4.95616976
6DNA deamination (GO:0045006)4.86812950
7platelet dense granule organization (GO:0060155)4.81306587
8translational termination (GO:0006415)4.77681784
9neutrophil activation (GO:0042119)4.59487601
10antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.48407630
11antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.48407630
12negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.35102753
13negative regulation of cell killing (GO:0031342)4.35102753
14positive regulation of mast cell activation (GO:0033005)4.25627507
15positive regulation of B cell differentiation (GO:0045579)4.24356972
16megakaryocyte development (GO:0035855)4.23242766
17antigen processing and presentation via MHC class Ib (GO:0002475)4.21885645
18positive regulation by symbiont of host defense response (GO:0052509)4.21843171
19modulation by symbiont of host defense response (GO:0052031)4.21843171
20modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.21843171
21modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.21843171
22positive regulation by organism of defense response of other organism involved in symbiotic interact4.21843171
23modulation by symbiont of host immune response (GO:0052553)4.21843171
24SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.17609204
25granulocyte activation (GO:0036230)4.16724828
26translational elongation (GO:0006414)4.15557592
27leukocyte migration involved in inflammatory response (GO:0002523)4.13606521
28cotranslational protein targeting to membrane (GO:0006613)4.07275454
29thrombin receptor signaling pathway (GO:0070493)4.07127253
30protein targeting to ER (GO:0045047)4.03932791
31ribosomal small subunit biogenesis (GO:0042274)4.01877904
32antigen processing and presentation of endogenous antigen (GO:0019883)3.97158264
33negative regulation of erythrocyte differentiation (GO:0045647)3.97028394
34microglial cell activation (GO:0001774)3.90390602
35establishment of protein localization to endoplasmic reticulum (GO:0072599)3.85175824
36protein localization to endoplasmic reticulum (GO:0070972)3.85126588
37regulation of platelet aggregation (GO:0090330)3.84044433
38G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)3.83301698
39telomere maintenance via semi-conservative replication (GO:0032201)3.81021179
40lymphoid progenitor cell differentiation (GO:0002320)3.80231912
41macrophage activation involved in immune response (GO:0002281)3.77835297
42positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.76729738
43nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.76454636
44myeloid cell activation involved in immune response (GO:0002275)3.73670733
45detection of other organism (GO:0098543)3.72594983
46response to interferon-beta (GO:0035456)3.72509014
47maturation of SSU-rRNA (GO:0030490)3.65855970
48viral life cycle (GO:0019058)3.65144239
49response to peptidoglycan (GO:0032494)3.63919024
50regulation of platelet activation (GO:0010543)3.56799532
51positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.55818311
52positive regulation of gamma-delta T cell activation (GO:0046645)3.55557006
53DNA strand elongation involved in DNA replication (GO:0006271)3.53740400
54detection of bacterium (GO:0016045)3.53340438
55cellular protein complex disassembly (GO:0043624)3.51192121
56mast cell activation (GO:0045576)3.49476246
57endosome to melanosome transport (GO:0035646)3.47743567
58endosome to pigment granule transport (GO:0043485)3.47743567
59regulation of mast cell activation (GO:0033003)3.47677803
60negative regulation of interleukin-12 production (GO:0032695)3.46427951
61mature B cell differentiation involved in immune response (GO:0002313)3.44870986
62DNA strand elongation (GO:0022616)3.44272737
63regulation of mast cell degranulation (GO:0043304)3.42222028
64regulation of regulatory T cell differentiation (GO:0045589)3.40197227
65negative regulation of T-helper cell differentiation (GO:0045623)3.39914996
66negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.39914996
67positive regulation of type 2 immune response (GO:0002830)3.38979431
68regulation of T-helper 1 cell differentiation (GO:0045625)3.37880694
69cellular extravasation (GO:0045123)3.37402620
70negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.35267227
71detection of molecule of bacterial origin (GO:0032490)3.34443735
72regulation of gamma-delta T cell activation (GO:0046643)3.33625085
73leukocyte degranulation (GO:0043299)3.33464535
74translational initiation (GO:0006413)3.31342587
75telomere maintenance via recombination (GO:0000722)3.31282033
76regulation of B cell differentiation (GO:0045577)3.31253469
77secretory granule organization (GO:0033363)3.30732178
78necroptotic process (GO:0070266)3.25783077
79detection of external biotic stimulus (GO:0098581)3.23698594
80interferon-gamma-mediated signaling pathway (GO:0060333)3.23684264
81response to host immune response (GO:0052572)3.23267140
82response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.23267140
83positive regulation of mast cell activation involved in immune response (GO:0033008)3.23212963
84positive regulation of mast cell degranulation (GO:0043306)3.23212963
85regulation of mast cell activation involved in immune response (GO:0033006)3.22513563
86deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.17398495
87protein complex disassembly (GO:0043241)3.17272464
88purinergic nucleotide receptor signaling pathway (GO:0035590)3.14986560
89regulation of alpha-beta T cell proliferation (GO:0046640)3.14027242
90regulation of interferon-beta biosynthetic process (GO:0045357)3.12877686
91polyketide metabolic process (GO:0030638)3.12679562
92doxorubicin metabolic process (GO:0044598)3.12679562
93daunorubicin metabolic process (GO:0044597)3.12679562
94defense response to protozoan (GO:0042832)3.12608072
95regulation of erythrocyte differentiation (GO:0045646)3.10784187
96regulation of T-helper 2 cell differentiation (GO:0045628)3.08196989
97macrophage activation (GO:0042116)3.08014982
98protein neddylation (GO:0045116)3.07870650
99positive regulation of cellular amide metabolic process (GO:0034250)3.06410776
100T cell homeostasis (GO:0043029)3.04927529
101response to interferon-alpha (GO:0035455)3.04596546
102dendritic cell chemotaxis (GO:0002407)3.04531596
103response to protozoan (GO:0001562)3.04449906
104positive regulation of B cell mediated immunity (GO:0002714)3.04262815
105positive regulation of immunoglobulin mediated immune response (GO:0002891)3.04262815
106lipoxygenase pathway (GO:0019372)3.02280103
107positive regulation of alpha-beta T cell proliferation (GO:0046641)2.99824678
108embryonic hemopoiesis (GO:0035162)2.99808157
109mast cell activation involved in immune response (GO:0002279)2.99789517
110mast cell degranulation (GO:0043303)2.99789517
111regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.99486460
112nuclear-transcribed mRNA catabolic process (GO:0000956)2.99313162
113negative regulation of interleukin-17 production (GO:0032700)2.99136608
114myeloid dendritic cell activation (GO:0001773)2.96631200
115macromolecular complex disassembly (GO:0032984)2.96418847
116dendritic cell migration (GO:0036336)2.95557901
117negative regulation of lymphocyte mediated immunity (GO:0002707)2.95428706
118DNA replication initiation (GO:0006270)2.94466320
119regulation of necroptotic process (GO:0060544)2.93842629
120positive regulation of toll-like receptor signaling pathway (GO:0034123)2.93501717
121lymph node development (GO:0048535)2.93184561
122germinal center formation (GO:0002467)2.92878794
123mature B cell differentiation (GO:0002335)2.91210742
124negative regulation of T cell mediated immunity (GO:0002710)2.91030779
125immunoglobulin mediated immune response (GO:0016064)2.90627155
126mitotic recombination (GO:0006312)2.90347314
127T cell migration (GO:0072678)2.90324283
128negative regulation of phagocytosis (GO:0050765)2.89924615
129response to host (GO:0075136)2.89342574
130response to host defenses (GO:0052200)2.89342574
131response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.89342574
132mRNA catabolic process (GO:0006402)2.87758652
133G-protein coupled purinergic receptor signaling pathway (GO:0035588)2.87480828
134regulation of MHC class II biosynthetic process (GO:0045346)2.86933180
135regulation of memory T cell differentiation (GO:0043380)2.85314619
136regulation of tolerance induction (GO:0002643)2.83523382
137regulation of myeloid leukocyte mediated immunity (GO:0002886)2.82825179
138detection of biotic stimulus (GO:0009595)2.81468456
139positive regulation of granulocyte differentiation (GO:0030854)2.78944082
140adenosine receptor signaling pathway (GO:0001973)2.78833760
141regulation of interleukin-17 production (GO:0032660)2.78726968
142fucose catabolic process (GO:0019317)2.78367176
143L-fucose metabolic process (GO:0042354)2.78367176
144L-fucose catabolic process (GO:0042355)2.78367176
145Arp2/3 complex-mediated actin nucleation (GO:0034314)2.78179675
146leukocyte aggregation (GO:0070486)2.77038687
147positive regulation of isotype switching (GO:0045830)2.76786352
148purine-containing compound salvage (GO:0043101)2.75838608
149ribosomal large subunit biogenesis (GO:0042273)2.75675965
150tolerance induction (GO:0002507)2.73579096
151RNA catabolic process (GO:0006401)2.73559997
152regulation of dendritic cell antigen processing and presentation (GO:0002604)2.73253023
153telomere maintenance via telomere lengthening (GO:0010833)2.71579787
154programmed necrotic cell death (GO:0097300)2.68269774
155positive regulation of macrophage differentiation (GO:0045651)2.67345942
156cellular response to thyroid hormone stimulus (GO:0097067)2.65043139
157angiogenesis involved in wound healing (GO:0060055)2.64183516
158regulation of B cell receptor signaling pathway (GO:0050855)2.64136971
159DNA unwinding involved in DNA replication (GO:0006268)2.62999022
160protein targeting to membrane (GO:0006612)2.58301138
161regulation of necrotic cell death (GO:0010939)2.57527984
162B cell mediated immunity (GO:0019724)2.56846512
163regulation of gamma-delta T cell differentiation (GO:0045586)2.55076231
164B cell receptor signaling pathway (GO:0050853)2.53029992
165pseudouridine synthesis (GO:0001522)2.52855165
166leukocyte homeostasis (GO:0001776)2.52379794
167cellular response to interferon-beta (GO:0035458)2.52335419
168positive regulation of T cell mediated cytotoxicity (GO:0001916)2.50548440
169Peyers patch development (GO:0048541)2.48473651
170mucosal-associated lymphoid tissue development (GO:0048537)2.48473651
171nucleotide-excision repair, DNA gap filling (GO:0006297)2.48217132
172myeloid dendritic cell differentiation (GO:0043011)2.47967511
173granulocyte differentiation (GO:0030851)2.46937683
174NIK/NF-kappaB signaling (GO:0038061)2.46609726
175response to type I interferon (GO:0034340)2.45375271
176type I interferon signaling pathway (GO:0060337)2.45280958
177cellular response to type I interferon (GO:0071357)2.45280958
178ribonucleoprotein complex biogenesis (GO:0022613)2.44862621

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.77729422
2SCL_19346495_ChIP-Seq_HPC-7_Human4.11906593
3IRF8_22096565_ChIP-ChIP_GC-B_Human3.67194444
4* MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.20259921
5* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse3.05735112
6* IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.04051789
7ELF1_17652178_ChIP-ChIP_JURKAT_Human3.02993821
8EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.02859158
9RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.93028270
10MYC_18555785_ChIP-Seq_MESCs_Mouse2.77187076
11TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.76361177
12FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.64503582
13* SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.62286300
14* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human2.61331191
15Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.59264492
16BP1_19119308_ChIP-ChIP_Hs578T_Human2.46489867
17SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.42029788
18GATA1_22025678_ChIP-Seq_K562_Human2.38420575
19MYB_21317192_ChIP-Seq_ERMYB_Mouse2.35531483
20NOTCH1_21737748_ChIP-Seq_TLL_Human2.30501728
21* SPI1_23547873_ChIP-Seq_NB4_Human2.25730493
22LYL1_20887958_ChIP-Seq_HPC-7_Mouse2.25330480
23STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.24378354
24VDR_21846776_ChIP-Seq_THP-1_Human2.17997648
25ERG_20887958_ChIP-Seq_HPC-7_Mouse2.13777956
26MYC_22102868_ChIP-Seq_BL_Human2.12876761
27SFPI1_20887958_ChIP-Seq_HPC-7_Mouse2.11721642
28HOXB4_20404135_ChIP-ChIP_EML_Mouse2.08750292
29E2F4_17652178_ChIP-ChIP_JURKAT_Human2.07606360
30EGR1_19374776_ChIP-ChIP_THP-1_Human2.06634068
31GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human2.04867619
32ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.00509742
33* IRF8_21731497_ChIP-ChIP_J774_Mouse1.99902572
34EST1_17652178_ChIP-ChIP_JURKAT_Human1.99625024
35LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.93059972
36RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.90675455
37GABP_17652178_ChIP-ChIP_JURKAT_Human1.87259775
38MYC_18358816_ChIP-ChIP_MESCs_Mouse1.86849799
39SMAD_19615063_ChIP-ChIP_OVARY_Human1.86311780
40* VDR_23849224_ChIP-Seq_CD4+_Human1.86001014
41HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.85827665
42STAT4_19710469_ChIP-ChIP_TH1__Mouse1.85359376
43MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.85117202
44* GATA1_19941826_ChIP-Seq_K562_Human1.84235903
45RUNX1_22412390_ChIP-Seq_EML_Mouse1.83519497
46NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.82456739
47IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.77593361
48MYB_26560356_Chip-Seq_TH2_Human1.77210718
49FOXP3_21729870_ChIP-Seq_TREG_Human1.75558946
50FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.72945788
51GATA2_21666600_ChIP-Seq_HMVEC_Human1.71725685
52VDR_24763502_ChIP-Seq_THP-1_Human1.70869718
53JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.70733545
54VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.70707949
55FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.69820185
56CIITA_25753668_ChIP-Seq_RAJI_Human1.68640878
57GATA1_22383799_ChIP-Seq_G1ME_Mouse1.68531641
58FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.68401534
59NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.66440454
60* GATA2_19941826_ChIP-Seq_K562_Human1.65447652
61SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.64137744
62GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.63571308
63ETS1_20019798_ChIP-Seq_JURKAT_Human1.63490306
64MYC_19030024_ChIP-ChIP_MESCs_Mouse1.62690720
65MAF_26560356_Chip-Seq_TH1_Human1.61645938
66MYB_26560356_Chip-Seq_TH1_Human1.61334521
67PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.60854424
68VDR_24787735_ChIP-Seq_THP-1_Human1.58913162
69GATA3_26560356_Chip-Seq_TH2_Human1.58737337
70GATA2_22383799_ChIP-Seq_G1ME_Mouse1.54507961
71SRF_21415370_ChIP-Seq_HL-1_Mouse1.53889943
72* IRF8_27001747_Chip-Seq_BMDM_Mouse1.52173618
73KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.52030746
74MYC_19079543_ChIP-ChIP_MESCs_Mouse1.50927984
75GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.50637294
76XRN2_22483619_ChIP-Seq_HELA_Human1.48317312
77PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.46706313
78BRD4_27068464_Chip-Seq_AML-cells_Mouse1.41565253
79UTX_26944678_Chip-Seq_JUKART_Human1.39599775
80TCF7_22412390_ChIP-Seq_EML_Mouse1.38319832
81FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.38033590
82HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.37210812
83* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.34744969
84STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.31150498
85NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.29529962
86RUNX_20019798_ChIP-Seq_JUKART_Human1.29337820
87NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.28395777
88MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.28125238
89NELFA_20434984_ChIP-Seq_ESCs_Mouse1.27626718
90E2F1_21310950_ChIP-Seq_MCF-7_Human1.27559624
91FOXM1_23109430_ChIP-Seq_U2OS_Human1.27389143
92E2F1_18555785_ChIP-Seq_MESCs_Mouse1.24516228
93GABP_19822575_ChIP-Seq_HepG2_Human1.23268203
94STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.23138299
95CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.22997736
96IKZF1_21737484_ChIP-ChIP_HCT116_Human1.21012285
97ELK1_19687146_ChIP-ChIP_HELA_Human1.20936916
98CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.20477045
99CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.16427782
100* GATA1_19941827_ChIP-Seq_MEL_Mouse1.15946971
101PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.15482755
102GATA1_19941827_ChIP-Seq_MEL86_Mouse1.15479697
103HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.13848818
104SPI1_23127762_ChIP-Seq_K562_Human1.11956265
105CREB1_15753290_ChIP-ChIP_HEK293T_Human1.11928050
106TTF2_22483619_ChIP-Seq_HELA_Human1.11754054
107E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.10535647
108CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.10313333
109DCP1A_22483619_ChIP-Seq_HELA_Human1.08104592
110* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.07045679
111MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.04578846
112ZFX_18555785_ChIP-Seq_MESCs_Mouse1.03312060
113ETS1_22383799_ChIP-Seq_G1ME_Mouse1.02567654
114STAT6_21828071_ChIP-Seq_BEAS2B_Human1.02008524
115SMRT_27268052_Chip-Seq_Bcells_Human1.01818067
116MAF_26560356_Chip-Seq_TH2_Human1.01129498
117PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.00008211
118SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.96692370
119PU_27001747_Chip-Seq_BMDM_Mouse0.96411229
120STAT1_20625510_ChIP-Seq_HELA_Human0.95486054
121CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.95108374
122RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.93914647
123THAP11_20581084_ChIP-Seq_MESCs_Mouse0.93782943
124PU.1_20513432_ChIP-Seq_Bcells_Mouse0.93535870
125FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92177041
126GATA3_27048872_Chip-Seq_THYMUS_Human0.90758998
127NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.90132959
128SPI1_20517297_ChIP-Seq_HL60_Human0.89016296
129CDX2_19796622_ChIP-Seq_MESCs_Mouse0.87786201
130CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.86983442
131SALL4_22934838_ChIP-ChIP_CD34+_Human0.85686775
132ELK4_26923725_Chip-Seq_MESODERM_Mouse0.85138344
133EGR1_23403033_ChIP-Seq_LIVER_Mouse0.84829947
134NCOR1_26117541_ChIP-Seq_K562_Human0.81840501
135GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80527184
136KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.79084485
137FOXO3_23340844_ChIP-Seq_DLD1_Human0.78506338
138VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.78046717
139GATA3_26560356_Chip-Seq_TH1_Human0.72566584
140ESR1_20079471_ChIP-ChIP_T-47D_Human0.71567877
141KDM2B_26808549_Chip-Seq_SUP-B15_Human0.67397674
142RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.67309115
143JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.66318339
144PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.65353072

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002396_abnormal_hematopoietic_system4.51257894
2MP0001835_abnormal_antigen_presentation3.72154932
3MP0005174_abnormal_tail_pigmentation3.02030855
4MP0005671_abnormal_response_to2.89927604
5MP0004808_abnormal_hematopoietic_stem2.87550215
6MP0005464_abnormal_platelet_physiology2.87244468
7MP0000685_abnormal_immune_system2.81023956
8MP0008004_abnormal_stomach_pH2.80900985
9MP0005397_hematopoietic_system_phenotyp2.80494110
10MP0001545_abnormal_hematopoietic_system2.80494110
11MP0009785_altered_susceptibility_to2.65058683
12MP0005075_abnormal_melanosome_morpholog2.52627206
13MP0000465_gastrointestinal_hemorrhage2.50606316
14MP0003763_abnormal_thymus_physiology2.47041179
15MP0004147_increased_porphyrin_level2.39974229
16* MP0002398_abnormal_bone_marrow2.37427955
17MP0002148_abnormal_hypersensitivity_rea2.31092705
18* MP0005025_abnormal_response_to2.28943657
19* MP0001800_abnormal_humoral_immune2.25209853
20* MP0002420_abnormal_adaptive_immunity2.17229770
21* MP0002452_abnormal_antigen_presenting2.15418575
22MP0000490_abnormal_crypts_of2.15004967
23* MP0001819_abnormal_immune_cell2.14735648
24MP0002095_abnormal_skin_pigmentation2.13706013
25MP0003724_increased_susceptibility_to2.12237205
26* MP0002723_abnormal_immune_serum2.10685360
27MP0005000_abnormal_immune_tolerance2.09609791
28MP0002166_altered_tumor_susceptibility2.08538652
29MP0008057_abnormal_DNA_replication2.07800459
30MP0001853_heart_inflammation2.02819811
31MP0000689_abnormal_spleen_morphology2.01461444
32MP0002419_abnormal_innate_immunity1.97577613
33* MP0000716_abnormal_immune_system1.97302153
34MP0001873_stomach_inflammation1.95111672
35MP0002722_abnormal_immune_system1.94964802
36MP0003436_decreased_susceptibility_to1.93599817
37MP0010094_abnormal_chromosome_stability1.92825544
38MP0004510_myositis1.87402040
39MP0005387_immune_system_phenotype1.86351679
40MP0001790_abnormal_immune_system1.86351679
41* MP0002429_abnormal_blood_cell1.85469244
42MP0010155_abnormal_intestine_physiology1.82668682
43MP0008007_abnormal_cellular_replicative1.80637026
44MP0003693_abnormal_embryo_hatching1.72116027
45MP0003866_abnormal_defecation1.67763310
46MP0008058_abnormal_DNA_repair1.67727384
47MP0009333_abnormal_splenocyte_physiolog1.61973992
48MP0000015_abnormal_ear_pigmentation1.59080079
49MP0002405_respiratory_system_inflammati1.58619964
50MP0001986_abnormal_taste_sensitivity1.56751411
51MP0002006_tumorigenesis1.56238816
52MP0006054_spinal_hemorrhage1.54410305
53MP0000703_abnormal_thymus_morphology1.53438726
54MP0003077_abnormal_cell_cycle1.43782712
55MP0008260_abnormal_autophagy1.39707442
56MP0001845_abnormal_inflammatory_respons1.38608981
57MP0001851_eye_inflammation1.38096757
58MP0009278_abnormal_bone_marrow1.36140560
59MP0009379_abnormal_foot_pigmentation1.23902990
60MP0002019_abnormal_tumor_incidence1.23649479
61MP0002877_abnormal_melanocyte_morpholog1.21804222
62MP0003075_altered_response_to1.21206528
63MP0004381_abnormal_hair_follicle1.20474522
64MP0008469_abnormal_protein_level1.19771640
65MP0003172_abnormal_lysosome_physiology1.18196356
66MP0006292_abnormal_olfactory_placode1.15359213
67MP0004883_abnormal_blood_vessel1.13095529
68MP0004957_abnormal_blastocyst_morpholog1.12275046
69MP0003111_abnormal_nucleus_morphology1.11972350
70MP0002132_abnormal_respiratory_system1.11864169
71MP0002998_abnormal_bone_remodeling1.10345100
72MP0003943_abnormal_hepatobiliary_system1.06133211
73MP0000249_abnormal_blood_vessel1.04325535
74MP0003656_abnormal_erythrocyte_physiolo1.01606559
75MP0000313_abnormal_cell_death1.00601678
76MP0005167_abnormal_blood-brain_barrier0.98764449
77MP0005166_decreased_susceptibility_to0.97824609
78MP0004947_skin_inflammation0.95318291
79MP0005083_abnormal_biliary_tract0.93128776
80MP0003448_altered_tumor_morphology0.92405365
81MP0006082_CNS_inflammation0.88281042
82MP0003300_gastrointestinal_ulcer0.86916481
83MP0005164_abnormal_response_to0.86023390
84MP0000858_altered_metastatic_potential0.85825417
85MP0005058_abnormal_lysosome_morphology0.85161633
86MP0003186_abnormal_redox_activity0.84533649
87MP0003566_abnormal_cell_adhesion0.84127799
88MP0005310_abnormal_salivary_gland0.84120203
89MP0000343_altered_response_to0.83623799
90MP0001533_abnormal_skeleton_physiology0.83070956
91MP0003806_abnormal_nucleotide_metabolis0.82389785
92MP0008874_decreased_physiological_sensi0.82371893
93MP0003191_abnormal_cellular_cholesterol0.80558449
94MP0003045_fibrosis0.79877614
95MP0001188_hyperpigmentation0.79714293
96MP0000569_abnormal_digit_pigmentation0.78192112
97MP0005409_darkened_coat_color0.78114675
98MP0003828_pulmonary_edema0.77991526
99MP0005084_abnormal_gallbladder_morpholo0.77936799
100MP0000230_abnormal_systemic_arterial0.77795108
101MP0000371_diluted_coat_color0.77773654
102MP0005451_abnormal_body_composition0.77644331
103MP0002075_abnormal_coat/hair_pigmentati0.77163988
104MP0010352_gastrointestinal_tract_polyps0.76641201
105MP0009764_decreased_sensitivity_to0.75459512
106MP0003453_abnormal_keratinocyte_physiol0.73299492
107MP0001663_abnormal_digestive_system0.73095025
108MP0001348_abnormal_lacrimal_gland0.71505219
109MP0004130_abnormal_muscle_cell0.71329371
110MP0002933_joint_inflammation0.70825088
111MP0001764_abnormal_homeostasis0.69405006
112MP0009763_increased_sensitivity_to0.69115915
113MP0003786_premature_aging0.68527027
114MP0000681_abnormal_thyroid_gland0.68074090
115MP0003183_abnormal_peptide_metabolism0.66987005
116MP0004484_altered_response_of0.64907901
117MP0009697_abnormal_copulation0.64378109
118MP0000477_abnormal_intestine_morphology0.63855272
119MP0002332_abnormal_exercise_endurance0.63806193
120MP0009765_abnormal_xenobiotic_induced0.63690443
121MP0006036_abnormal_mitochondrial_physio0.63173929
122MP0003638_abnormal_response/metabolism_0.62918914
123MP0003091_abnormal_cell_migration0.62530788
124MP0003303_peritoneal_inflammation0.62079148
125MP0002009_preneoplasia0.60837419
126MP0005390_skeleton_phenotype0.60277355
127MP0001765_abnormal_ion_homeostasis0.58720955
128MP0008872_abnormal_physiological_respon0.58666672
129MP0003795_abnormal_bone_structure0.58527082
130MP0010307_abnormal_tumor_latency0.58063076
131MP0009642_abnormal_blood_homeostasis0.57391216
132MP0005381_digestive/alimentary_phenotyp0.57093717
133MP0005165_increased_susceptibility_to0.56607748
134MP0000350_abnormal_cell_proliferation0.56598250
135MP0005410_abnormal_fertilization0.55060193

Predicted human phenotypes

RankGene SetZ-score
1Increased mean platelet volume (HP:0011877)5.65435853
2Aplastic anemia (HP:0001915)5.33289879
3Thrombocytosis (HP:0001894)5.32198103
4Petechiae (HP:0000967)4.85470364
5Abnormal number of erythroid precursors (HP:0012131)4.66508115
6Abnormality of cells of the erythroid lineage (HP:0012130)4.65579117
7IgM deficiency (HP:0002850)4.47521652
8Prolonged bleeding time (HP:0003010)4.44182111
9Chronic otitis media (HP:0000389)4.28315097
10Stomatitis (HP:0010280)4.13988257
11Reticulocytopenia (HP:0001896)3.90649648
12Elevated erythrocyte sedimentation rate (HP:0003565)3.86389657
13Myositis (HP:0100614)3.62212852
14Recurrent abscess formation (HP:0002722)3.57260871
15Chronic obstructive pulmonary disease (HP:0006510)3.47387712
16Obstructive lung disease (HP:0006536)3.47387712
17Panhypogammaglobulinemia (HP:0003139)3.46148873
18Abnormality of the heme biosynthetic pathway (HP:0010472)3.44147410
19Epistaxis (HP:0000421)3.42364904
20Abnormal platelet function (HP:0011869)3.31354327
21Impaired platelet aggregation (HP:0003540)3.31354327
22Recurrent bacterial skin infections (HP:0005406)3.30254250
23Abnormality of T cell physiology (HP:0011840)3.22348973
24Recurrent viral infections (HP:0004429)3.22203810
25Pallor (HP:0000980)3.16646459
26Abnormal delayed hypersensitivity skin test (HP:0002963)3.10201400
27Reduced antithrombin III activity (HP:0001976)3.06754280
28Acute myeloid leukemia (HP:0004808)3.04994320
29Gastrointestinal infarctions (HP:0005244)3.04588319
30Increased IgM level (HP:0003496)3.04375610
31Keratoconjunctivitis sicca (HP:0001097)3.02214126
32Recurrent bronchitis (HP:0002837)3.01008860
33Hyperlipoproteinemia (HP:0010980)2.99378050
34Type I transferrin isoform profile (HP:0003642)2.97986561
35T lymphocytopenia (HP:0005403)2.97819120
36Recurrent gram-negative bacterial infections (HP:0005420)2.93640986
37Abnormality of T cell number (HP:0011839)2.92665558
38Autoimmune hemolytic anemia (HP:0001890)2.82508851
39Keratoconjunctivitis (HP:0001096)2.82102333
40Acute lymphatic leukemia (HP:0006721)2.81295654
41Recurrent fungal infections (HP:0002841)2.79285430
42Type 2 muscle fiber atrophy (HP:0003554)2.78398091
43Muscle fiber atrophy (HP:0100295)2.78322875
44Myelodysplasia (HP:0002863)2.77557349
45Abnormality of the prostate (HP:0008775)2.69148412
46Poikiloderma (HP:0001029)2.68946883
47Gingival bleeding (HP:0000225)2.67319582
48Albinism (HP:0001022)2.64077630
49Cellulitis (HP:0100658)2.61614858
50Dyschromatopsia (HP:0007641)2.60064860
51Urticaria (HP:0001025)2.58578985
52Pancytopenia (HP:0001876)2.58437076
53Joint swelling (HP:0001386)2.58143158
54Inflammation of the large intestine (HP:0002037)2.55617076
55Macrocytic anemia (HP:0001972)2.55451264
56Meningitis (HP:0001287)2.55244394
57Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.55236465
58Abnormal protein N-linked glycosylation (HP:0012347)2.55236465
59Abnormal protein glycosylation (HP:0012346)2.55236465
60Abnormal glycosylation (HP:0012345)2.55236465
61Gastrointestinal inflammation (HP:0004386)2.54272762
62Agammaglobulinemia (HP:0004432)2.53795702
63Conjunctival telangiectasia (HP:0000524)2.53426895
64Abnormality of the vasculature of the conjunctiva (HP:0008054)2.52923098
65Abnormality of B cell number (HP:0010975)2.52901484
66B lymphocytopenia (HP:0010976)2.52901484
67Gangrene (HP:0100758)2.52217565
6811 pairs of ribs (HP:0000878)2.52130086
69Amaurosis fugax (HP:0100576)2.51341864
70Purpura (HP:0000979)2.50096944
71Pulmonary infiltrates (HP:0002113)2.49681918
72Abnormality of the nasal mucosa (HP:0000433)2.47840909
73Bruising susceptibility (HP:0000978)2.47180125
74Abnormality of T cells (HP:0002843)2.44448442
75Lymphopenia (HP:0001888)2.38793634
76Hemoptysis (HP:0002105)2.38596659
77Recurrent skin infections (HP:0001581)2.35968386
78Nasal polyposis (HP:0100582)2.35939846
79Pulmonary embolism (HP:0002204)2.35876160
80Lymphoma (HP:0002665)2.34180466
81Fatigue (HP:0012378)2.33484268
82Episodic fever (HP:0001954)2.33368868
83Poikilocytosis (HP:0004447)2.32494526
84Gingivitis (HP:0000230)2.32183752
85Gastrointestinal stroma tumor (HP:0100723)2.32066489
86Abnormality of cells of the lymphoid lineage (HP:0012140)2.31086566
87Abnormality of iron homeostasis (HP:0011031)2.26599397
88Hepatosplenomegaly (HP:0001433)2.26303216
89Encephalitis (HP:0002383)2.25535824
90IgG deficiency (HP:0004315)2.24894695
91Vertigo (HP:0002321)2.24608596
92Abnormality of the common coagulation pathway (HP:0010990)2.24455299
93Entropion (HP:0000621)2.23180705
94Eosinophilia (HP:0001880)2.22821660
95Birth length less than 3rd percentile (HP:0003561)2.19813959
96Microcytic anemia (HP:0001935)2.17870811
97Neutropenia (HP:0001875)2.17516959
98Acanthocytosis (HP:0001927)2.16592385
99Increased serum ferritin (HP:0003281)2.16583961
100Hypoplasia of the thymus (HP:0000778)2.15820639
101Abnormal platelet volume (HP:0011876)2.15467428
102Orchitis (HP:0100796)2.15374486
103Vasculitis (HP:0002633)2.15274100
104Abnormality of the columella (HP:0009929)2.15150182
105Vacuolated lymphocytes (HP:0001922)2.14605810
106Recurrent sinusitis (HP:0011108)2.14533870
107Anorexia (HP:0002039)2.14408579
108Eczematoid dermatitis (HP:0000976)2.14285487
109Pustule (HP:0200039)2.13533963
110Osteomyelitis (HP:0002754)2.11728893
111Recurrent cutaneous fungal infections (HP:0011370)2.10898935
112Chronic mucocutaneous candidiasis (HP:0002728)2.10898935
113Granulocytopenia (HP:0001913)2.10824864
114Hypoproteinemia (HP:0003075)2.08405865
115Hypergammaglobulinemia (HP:0010702)2.08246327
116Basal ganglia calcification (HP:0002135)2.06995048
117Abnormality of macrophages (HP:0004311)2.06860582
118Interstitial pulmonary disease (HP:0006530)2.05168338
119Leukocytosis (HP:0001974)2.02758211
120Autoimmune thrombocytopenia (HP:0001973)2.01603793
121Thrombophlebitis (HP:0004418)2.01293262
122Mediastinal lymphadenopathy (HP:0100721)2.00435015
123Erythema (HP:0010783)1.99921095
124Paralysis (HP:0003470)1.98045799
125Colitis (HP:0002583)1.98016041
126Optic neuritis (HP:0100653)1.97980698
127Retrobulbar optic neuritis (HP:0100654)1.97980698
128Spontaneous hematomas (HP:0007420)1.96332576
129Thyroiditis (HP:0100646)1.95857969
130Aplasia/Hypoplasia of the sacrum (HP:0008517)1.94625179
131Abnormality of transition element cation homeostasis (HP:0011030)1.93462278
132Menorrhagia (HP:0000132)1.93316864
133Increased IgE level (HP:0003212)1.93035282
134Acute hepatic failure (HP:0006554)1.93009524
135Polyneuropathy (HP:0001271)1.92710868
136Arthralgia (HP:0002829)1.91660724
137Chest pain (HP:0100749)1.91331404
138Severe visual impairment (HP:0001141)1.91025067
139Abnormality of DNA repair (HP:0003254)1.88859474
140Arterial thrombosis (HP:0004420)1.88392002
141Glomerulopathy (HP:0100820)1.87911517
142Patchy hypopigmentation of hair (HP:0011365)1.86361687
143Chronic sinusitis (HP:0011109)1.86262359
144Broad face (HP:0000283)1.84813396
145Abnormality of eosinophils (HP:0001879)1.82028472
146Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.81581294
147Decreased activity of mitochondrial respiratory chain (HP:0008972)1.81581294

Predicted kinase interactions (KEA)

RankGene SetZ-score
1KIT3.74126022
2MST43.27057304
3MAP4K13.16335906
4FLT32.97112198
5STK162.88162982
6BMPR22.60717690
7TEC2.53000185
8NME22.46468626
9WEE12.42241131
10CSF1R2.19893661
11TNIK2.19019370
12CSK2.18713753
13EEF2K2.18059582
14TGFBR12.06136438
15FGR1.99292595
16MAP3K121.97373699
17PIM21.95623117
18TXK1.91785458
19ACVR1B1.89892391
20MAP2K31.88711968
21MATK1.85532423
22* BTK1.84220680
23JAK31.84117978
24BMX1.83835859
25ZAP701.73199755
26VRK11.72111751
27TGFBR21.67239998
28CDK191.66320549
29TAOK31.65738948
30BRSK21.59921225
31JAK11.57816250
32IRAK41.53805833
33PTK2B1.51721293
34TBK11.51660838
35SYK1.48021756
36RPS6KB21.47357187
37MAPKAPK51.43219818
38IRAK11.38482267
39IKBKE1.36472564
40IKBKB1.36256544
41TYK21.33395228
42MUSK1.31654532
43BLK1.25207352
44MKNK11.22093230
45DYRK31.17591021
46JAK21.17379711
47STK241.14665709
48TIE11.14336212
49CCNB11.13284523
50MAP3K31.12485600
51PIM11.07240498
52GRK51.05548114
53CDC71.05166388
54PRPF4B1.01502999
55SCYL21.00290842
56MARK31.00014875
57MAPKAPK30.98758054
58CDK80.97172496
59FES0.95495394
60PASK0.95449040
61ATR0.93744493
62EPHB10.92944810
63MAP3K140.92044023
64BCKDK0.91503325
65NLK0.90706487
66CDK70.89424273
67MAP3K130.89314066
68TAOK10.88944116
69LRRK20.88930015
70* LYN0.87025174
71KDR0.86237931
72MAP3K60.85989247
73MAP3K50.85510947
74PDK10.84764059
75* LCK0.80359200
76RPS6KA40.80222027
77MAP2K60.79348419
78IRAK20.78127654
79MAP3K10.77831926
80CAMKK20.77774794
81BUB10.76867154
82STK100.75806870
83CLK10.75649795
84TLK10.75058860
85YES10.73130629
86IRAK30.72824753
87SRPK10.71075642
88EPHA30.70359193
89EIF2AK10.70148802
90NEK20.69962462
91ADRBK20.69506893
92HCK0.68400793
93CDK40.66892575
94DAPK10.64906655
95PRKG20.64876349
96PIK3CG0.64569122
97PRKCQ0.63974314
98TSSK60.63159831
99STK30.62919641
100CHUK0.61872747
101ITK0.61715660
102GRK70.61168097
103EIF2AK30.60021251
104ERN10.59960543
105GRK60.59189488
106CAMK10.58931418
107MAP3K110.58720261
108SIK30.58525303
109FYN0.58503492
110PDPK10.58391492
111STK40.58307349
112PAK40.56435363
113MAPK40.56250719
114MYLK0.54473406
115HIPK20.53083875
116FGFR30.52030693
117MAPK120.51770022
118MAP3K20.51595515
119BRSK10.49761686
120MKNK20.48963630
121RPS6KA60.47462505
122MAPK110.47158475
123PAK10.46979234
124TRPM70.45071145
125RIPK40.44209813
126RET0.43068331
127TAOK20.42782166
128TNK20.41287929
129AURKB0.40738722
130SGK20.40385352
131PRKD10.39675556
132ADRBK10.38859934
133ABL10.38277548
134SGK30.38136412
135RPS6KA50.37072321
136PRKCD0.36785069
137PKN20.36750586
138PIK3CA0.35971691
139ILK0.35470144
140RAF10.35194034
141CDK60.34573444
142DAPK20.34063336
143CDC42BPA0.33749365
144FGFR40.32920496
145TESK20.32737774
146MAPK70.30263191
147ERBB20.30057586
148FRK0.28265079
149IGF1R0.27524830
150DAPK30.27268919
151MAPKAPK20.27080219
152FER0.25343653

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.39665988
2Ribosome_Homo sapiens_hsa030104.11770149
3Mismatch repair_Homo sapiens_hsa034303.15250929
4Graft-versus-host disease_Homo sapiens_hsa053322.95942273
5Staphylococcus aureus infection_Homo sapiens_hsa051502.65302096
6Base excision repair_Homo sapiens_hsa034102.62419917
7Caffeine metabolism_Homo sapiens_hsa002322.52302660
8Primary immunodeficiency_Homo sapiens_hsa053402.49539590
9Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.41615168
10Homologous recombination_Homo sapiens_hsa034402.29398937
11Type I diabetes mellitus_Homo sapiens_hsa049402.21557004
12Non-homologous end-joining_Homo sapiens_hsa034502.03056455
13Pyrimidine metabolism_Homo sapiens_hsa002401.97890099
14Nucleotide excision repair_Homo sapiens_hsa034201.97150207
15Spliceosome_Homo sapiens_hsa030401.85003401
16Leishmaniasis_Homo sapiens_hsa051401.80471952
17Hematopoietic cell lineage_Homo sapiens_hsa046401.79139020
18RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.78160613
19Viral myocarditis_Homo sapiens_hsa054161.70285719
20RNA polymerase_Homo sapiens_hsa030201.69198675
21Herpes simplex infection_Homo sapiens_hsa051681.67282669
22Measles_Homo sapiens_hsa051621.61466683
23NF-kappa B signaling pathway_Homo sapiens_hsa040641.61441585
24Other glycan degradation_Homo sapiens_hsa005111.57970185
25Antigen processing and presentation_Homo sapiens_hsa046121.56664940
26Intestinal immune network for IgA production_Homo sapiens_hsa046721.52356402
27Rheumatoid arthritis_Homo sapiens_hsa053231.50066854
28Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.49836172
29Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.49471370
30Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.46146988
31Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.41474362
32Transcriptional misregulation in cancer_Homo sapiens_hsa052021.39698627
33Cell cycle_Homo sapiens_hsa041101.35369726
34Phagosome_Homo sapiens_hsa041451.34333409
35Fanconi anemia pathway_Homo sapiens_hsa034601.32525393
36* B cell receptor signaling pathway_Homo sapiens_hsa046621.32235089
37RNA degradation_Homo sapiens_hsa030181.28193358
38Toll-like receptor signaling pathway_Homo sapiens_hsa046201.26203872
39Jak-STAT signaling pathway_Homo sapiens_hsa046301.25896120
40Platelet activation_Homo sapiens_hsa046111.23344966
41N-Glycan biosynthesis_Homo sapiens_hsa005101.21882414
42Legionellosis_Homo sapiens_hsa051341.21435426
43Proteasome_Homo sapiens_hsa030501.20677584
44Acute myeloid leukemia_Homo sapiens_hsa052211.17067712
45NOD-like receptor signaling pathway_Homo sapiens_hsa046211.11586072
46Osteoclast differentiation_Homo sapiens_hsa043801.10998757
47RNA transport_Homo sapiens_hsa030131.06945038
48Shigellosis_Homo sapiens_hsa051311.06552388
49p53 signaling pathway_Homo sapiens_hsa041151.05646264
50Allograft rejection_Homo sapiens_hsa053301.04305570
51Purine metabolism_Homo sapiens_hsa002301.03560639
52SNARE interactions in vesicular transport_Homo sapiens_hsa041301.01333058
53Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.99452404
54Pertussis_Homo sapiens_hsa051330.99309025
55Asthma_Homo sapiens_hsa053100.99046523
56Influenza A_Homo sapiens_hsa051640.98804749
57Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.98225757
58Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.98186554
59Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.96865035
60Protein export_Homo sapiens_hsa030600.96480926
61Epstein-Barr virus infection_Homo sapiens_hsa051690.96249581
62One carbon pool by folate_Homo sapiens_hsa006700.95939399
63Hepatitis B_Homo sapiens_hsa051610.93409911
64Basal transcription factors_Homo sapiens_hsa030220.93208079
65Toxoplasmosis_Homo sapiens_hsa051450.89988871
66Folate biosynthesis_Homo sapiens_hsa007900.87061347
67Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.84618885
68Apoptosis_Homo sapiens_hsa042100.83928506
69Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.80481453
70Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.79845262
71Systemic lupus erythematosus_Homo sapiens_hsa053220.78007868
72Endocytosis_Homo sapiens_hsa041440.77386593
73Pentose phosphate pathway_Homo sapiens_hsa000300.76671580
74Malaria_Homo sapiens_hsa051440.75805479
75Thyroid cancer_Homo sapiens_hsa052160.73130238
76Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71702362
77Drug metabolism - other enzymes_Homo sapiens_hsa009830.71561584
78Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.70981286
79Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.69443390
80Viral carcinogenesis_Homo sapiens_hsa052030.67470509
81TNF signaling pathway_Homo sapiens_hsa046680.66121289
82Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.65415222
83Glycosaminoglycan degradation_Homo sapiens_hsa005310.64887763
84Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.64813465
85Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.63427484
86Tuberculosis_Homo sapiens_hsa051520.63285394
87Collecting duct acid secretion_Homo sapiens_hsa049660.62066220
88Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.60641920
89Cyanoamino acid metabolism_Homo sapiens_hsa004600.60628137
90Chronic myeloid leukemia_Homo sapiens_hsa052200.57300974
91Phospholipase D signaling pathway_Homo sapiens_hsa040720.57214138
92VEGF signaling pathway_Homo sapiens_hsa043700.57152996
93Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.55333563
94Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.55252030
95Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.54835404
96Sulfur relay system_Homo sapiens_hsa041220.54646397
97Lysosome_Homo sapiens_hsa041420.54408949
98alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.54015620
99Galactose metabolism_Homo sapiens_hsa000520.53379037
100Small cell lung cancer_Homo sapiens_hsa052220.53097323
101HTLV-I infection_Homo sapiens_hsa051660.51081964
102T cell receptor signaling pathway_Homo sapiens_hsa046600.51019498
103Salmonella infection_Homo sapiens_hsa051320.49427058
104Renal cell carcinoma_Homo sapiens_hsa052110.48414568
105Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.48295143
106Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.48262414
107Arachidonic acid metabolism_Homo sapiens_hsa005900.47856046
108Phosphatidylinositol signaling system_Homo sapiens_hsa040700.47810292
109Amoebiasis_Homo sapiens_hsa051460.47658705
110Leukocyte transendothelial migration_Homo sapiens_hsa046700.46073099
111Regulation of actin cytoskeleton_Homo sapiens_hsa048100.45655400
112Vascular smooth muscle contraction_Homo sapiens_hsa042700.45465714
113Sphingolipid signaling pathway_Homo sapiens_hsa040710.44070080
114Choline metabolism in cancer_Homo sapiens_hsa052310.43383873
115Adipocytokine signaling pathway_Homo sapiens_hsa049200.42296499
116Hepatitis C_Homo sapiens_hsa051600.41207458
117Chemokine signaling pathway_Homo sapiens_hsa040620.40194694
118Prolactin signaling pathway_Homo sapiens_hsa049170.39880778
119Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.39808824
120Serotonergic synapse_Homo sapiens_hsa047260.38900573
121Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.36569444
122AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.36141691
123African trypanosomiasis_Homo sapiens_hsa051430.34092583
124FoxO signaling pathway_Homo sapiens_hsa040680.33396723
125Non-small cell lung cancer_Homo sapiens_hsa052230.31987092
126Nitrogen metabolism_Homo sapiens_hsa009100.31934584
127Endometrial cancer_Homo sapiens_hsa052130.30979947
128Autoimmune thyroid disease_Homo sapiens_hsa053200.30818257
129Glycerophospholipid metabolism_Homo sapiens_hsa005640.30791201
130Pancreatic cancer_Homo sapiens_hsa052120.30779467
131mRNA surveillance pathway_Homo sapiens_hsa030150.30000217
132Gap junction_Homo sapiens_hsa045400.29931413
133Pancreatic secretion_Homo sapiens_hsa049720.29304009
134Dorso-ventral axis formation_Homo sapiens_hsa043200.28135489
135Rap1 signaling pathway_Homo sapiens_hsa040150.28061776
136Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.27481550
137Carbohydrate digestion and absorption_Homo sapiens_hsa049730.27262696
138Alcoholism_Homo sapiens_hsa050340.27022917
139HIF-1 signaling pathway_Homo sapiens_hsa040660.26498904
140Linoleic acid metabolism_Homo sapiens_hsa005910.25913476
141Regulation of autophagy_Homo sapiens_hsa041400.25862551
142Pentose and glucuronate interconversions_Homo sapiens_hsa000400.25505980
143Neurotrophin signaling pathway_Homo sapiens_hsa047220.25232598
144MAPK signaling pathway_Homo sapiens_hsa040100.25216621

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