CYSTM1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.36628753
2mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.97819993
3cellular ketone body metabolic process (GO:0046950)4.74167204
4energy coupled proton transport, down electrochemical gradient (GO:0015985)4.66080429
5ATP synthesis coupled proton transport (GO:0015986)4.66080429
6respiratory electron transport chain (GO:0022904)4.57692062
7electron transport chain (GO:0022900)4.54315201
8positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003574.54312001
9L-phenylalanine metabolic process (GO:0006558)4.52690091
10erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.52690091
11respiratory chain complex IV assembly (GO:0008535)4.43819815
12erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.35190864
13L-phenylalanine catabolic process (GO:0006559)4.35190864
14regulation of type B pancreatic cell apoptotic process (GO:2000674)4.28431106
15ketone body metabolic process (GO:1902224)4.24313010
16calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)4.22697104
17negative regulation of execution phase of apoptosis (GO:1900118)4.13428477
18cytochrome complex assembly (GO:0017004)4.11155171
19peptide hormone processing (GO:0016486)3.79728893
20inositol phosphate dephosphorylation (GO:0046855)3.74159715
21phosphorylated carbohydrate dephosphorylation (GO:0046838)3.74159715
22inositol phosphate catabolic process (GO:0071545)3.72008477
23endocrine pancreas development (GO:0031018)3.67742302
24nitric oxide biosynthetic process (GO:0006809)3.66247653
25protein neddylation (GO:0045116)3.64814085
26retinol metabolic process (GO:0042572)3.64604476
27auditory receptor cell differentiation (GO:0042491)3.63510687
28insulin secretion (GO:0030073)3.59450867
29energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.54656830
30ATP hydrolysis coupled proton transport (GO:0015991)3.54656830
31hydrogen ion transmembrane transport (GO:1902600)3.48044894
32xenobiotic catabolic process (GO:0042178)3.45493152
33phenol-containing compound catabolic process (GO:0019336)3.43865878
34signal peptide processing (GO:0006465)3.40585645
35positive regulation of gluconeogenesis (GO:0045722)3.27209736
36sensory perception of smell (GO:0007608)3.24943264
37glycerophospholipid catabolic process (GO:0046475)3.21288922
38regulation of extracellular matrix disassembly (GO:0010715)3.19835428
39regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022353.19825964
40positive regulation of insulin secretion (GO:0032024)3.18153954
41intestinal epithelial cell development (GO:0060576)3.14391101
42proton transport (GO:0015992)3.12432028
43ATP biosynthetic process (GO:0006754)3.11839200
44epithelial cell fate commitment (GO:0072148)3.10804459
45regulation of hexokinase activity (GO:1903299)3.09695609
46regulation of glucokinase activity (GO:0033131)3.09695609
47sphingomyelin metabolic process (GO:0006684)3.09003592
48pteridine-containing compound biosynthetic process (GO:0042559)3.08507613
49hydrogen transport (GO:0006818)3.06537337
50GDP-mannose metabolic process (GO:0019673)3.06110427
51axon ensheathment in central nervous system (GO:0032291)3.03791035
52central nervous system myelination (GO:0022010)3.03791035
53glandular epithelial cell differentiation (GO:0002067)3.01764182
54positive regulation of calcium ion import (GO:0090280)3.00302217
55NADH metabolic process (GO:0006734)2.98174764
56glutathione derivative biosynthetic process (GO:1901687)2.96727717
57glutathione derivative metabolic process (GO:1901685)2.96727717
58polyol catabolic process (GO:0046174)2.95568403
59macroautophagy (GO:0016236)2.95452251
60bundle of His cell to Purkinje myocyte communication (GO:0086069)2.93633652
61neuronal action potential (GO:0019228)2.92321512
62negative regulation of complement activation (GO:0045916)2.90459476
63C-terminal protein lipidation (GO:0006501)2.90412144
64potassium ion export (GO:0071435)2.86793639
65protein complex biogenesis (GO:0070271)2.86587963
66purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.85862121
67purine nucleoside triphosphate biosynthetic process (GO:0009145)2.85132163
68platelet dense granule organization (GO:0060155)2.81589988
69nitric oxide mediated signal transduction (GO:0007263)2.80429291
70glutathione biosynthetic process (GO:0006750)2.79493362
71regulation of oxidative phosphorylation (GO:0002082)2.78249477
72detection of calcium ion (GO:0005513)2.78230451
733-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.76408106
74purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.76408106
75transferrin transport (GO:0033572)2.76293653
76phosphatidylserine acyl-chain remodeling (GO:0036150)2.75150460
77negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.74004702
78protein localization to cilium (GO:0061512)2.72814923
79phenylpropanoid metabolic process (GO:0009698)2.72273544
80epithelial cilium movement (GO:0003351)2.71455422
81inositol phosphate-mediated signaling (GO:0048016)2.71098236
82oxidative phosphorylation (GO:0006119)2.70115732
83dopamine biosynthetic process (GO:0042416)2.69771138
84peptide hormone secretion (GO:0030072)2.69590842
85regulation of autophagic vacuole assembly (GO:2000785)2.69448846
86inner mitochondrial membrane organization (GO:0007007)2.69083874
87aromatic amino acid family catabolic process (GO:0009074)2.68656486
88nonribosomal peptide biosynthetic process (GO:0019184)2.68332912
89phosphatidylserine metabolic process (GO:0006658)2.65286589
90peptide secretion (GO:0002790)2.64853575
91glucosamine-containing compound catabolic process (GO:1901072)2.64416934
92positive regulation of histone H3-K4 methylation (GO:0051571)2.63614401
93axoneme assembly (GO:0035082)2.62128300
94C-terminal protein amino acid modification (GO:0018410)2.61781909
95positive regulation of peptide hormone secretion (GO:0090277)2.60559198
96trivalent inorganic cation transport (GO:0072512)2.60183544
97ferric iron transport (GO:0015682)2.60183544
98regulation of insulin secretion involved in cellular response to glucose stimulus (GO:0061178)2.57830326
99succinate metabolic process (GO:0006105)2.56804732
100response to water (GO:0009415)2.56580361
101primary alcohol metabolic process (GO:0034308)2.54223167
102negative regulation of protein activation cascade (GO:2000258)2.54097629
103lactate metabolic process (GO:0006089)2.53322532
104regulation of guanylate cyclase activity (GO:0031282)2.52448411
105chaperone-mediated protein transport (GO:0072321)2.51600766
106neurotransmitter catabolic process (GO:0042135)2.51244985
107sensory perception of chemical stimulus (GO:0007606)2.50948083
108regulation of execution phase of apoptosis (GO:1900117)2.50941245
109keratinocyte development (GO:0003334)2.50237380
110preassembly of GPI anchor in ER membrane (GO:0016254)2.49387402
111mitochondrial respiratory chain complex assembly (GO:0033108)2.49184539
112positive regulation of peptide secretion (GO:0002793)2.48766355
113nodal signaling pathway (GO:0038092)2.47437565
114regulation of vacuole organization (GO:0044088)2.47328837
115negative regulation of microtubule polymerization (GO:0031115)2.47199192
116adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.46483056
117membrane repolarization during action potential (GO:0086011)2.46061654
118mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.45813630
119mitochondrial respiratory chain complex I assembly (GO:0032981)2.45813630
120NADH dehydrogenase complex assembly (GO:0010257)2.45813630
121cytidine metabolic process (GO:0046087)2.45634751
122cytidine catabolic process (GO:0006216)2.45634751
123cytidine deamination (GO:0009972)2.45634751
124catechol-containing compound biosynthetic process (GO:0009713)2.43731229
125catecholamine biosynthetic process (GO:0042423)2.43731229
126positive regulation of TOR signaling (GO:0032008)2.43212031
127regulation of mitochondrial translation (GO:0070129)2.42293409
128regulation of cilium movement (GO:0003352)2.42071707
129regulation of protein targeting to membrane (GO:0090313)2.41623121
130alditol phosphate metabolic process (GO:0052646)2.41596525
131ribonucleoside triphosphate biosynthetic process (GO:0009201)2.41179831
132cilium movement (GO:0003341)2.41171079
133detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.40463912
134detection of temperature stimulus involved in sensory perception (GO:0050961)2.40463912
135regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.38836531
136regulation of heart rate by cardiac conduction (GO:0086091)2.38466693
137peptide transport (GO:0015833)2.38147973
138neurotransmitter biosynthetic process (GO:0042136)2.37284912
139regulation of insulin secretion (GO:0050796)2.36530235
140ER overload response (GO:0006983)2.36240866
141L-alpha-amino acid transmembrane transport (GO:1902475)2.35789185
142peptide biosynthetic process (GO:0043043)2.35417205
143negative regulation of humoral immune response (GO:0002921)2.35090223
144peptide metabolic process (GO:0006518)2.34720460
145positive regulation of glycolytic process (GO:0045821)2.34543804
146cobalamin metabolic process (GO:0009235)2.33614328
147basic amino acid transport (GO:0015802)2.33354871
148ventricular cardiac muscle cell action potential (GO:0086005)2.32973564
149establishment of melanosome localization (GO:0032401)2.32021283
150melanosome transport (GO:0032402)2.31270703
151digestion (GO:0007586)2.30491762
152pyrimidine-containing compound transmembrane transport (GO:0072531)2.30071150
153actin filament depolymerization (GO:0030042)2.29114813
154nucleoside triphosphate biosynthetic process (GO:0009142)2.28761930
155action potential (GO:0001508)2.27293446
156calcium-mediated signaling using intracellular calcium source (GO:0035584)2.26841980
157nucleotide-sugar biosynthetic process (GO:0009226)2.26433545
158regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.24299704
159phosphatidylethanolamine acyl-chain remodeling (GO:0036152)2.24115851
160cell communication involved in cardiac conduction (GO:0086065)2.21657954
161magnesium ion transport (GO:0015693)2.20774708
162establishment of pigment granule localization (GO:0051905)2.20632678
163establishment of protein localization to mitochondrial membrane (GO:0090151)2.19619792
164pigment granule transport (GO:0051904)2.19375525
165membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.18836594
166regulation of protein glycosylation (GO:0060049)2.17756460
167monovalent inorganic cation transport (GO:0015672)2.17151419
168nucleoside diphosphate phosphorylation (GO:0006165)2.16753220
169membrane budding (GO:0006900)2.16584297
170dopamine metabolic process (GO:0042417)2.16312886
171tricarboxylic acid cycle (GO:0006099)2.15547408
172neuron cell-cell adhesion (GO:0007158)2.14236546
173oligosaccharide catabolic process (GO:0009313)2.14214069
174positive regulation of protein targeting to membrane (GO:0090314)2.13966413
175water-soluble vitamin biosynthetic process (GO:0042364)2.13700469
176intraciliary transport (GO:0042073)2.13478045
177negative regulation of cation channel activity (GO:2001258)2.13103803

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.91921022
2EZH2_22144423_ChIP-Seq_EOC_Human2.76052561
3VDR_22108803_ChIP-Seq_LS180_Human2.51784670
4FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.45169780
5BMI1_23680149_ChIP-Seq_NPCS_Mouse2.13792070
6POU3F2_20337985_ChIP-ChIP_501MEL_Human2.12915963
7ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.98398045
8CDX2_19796622_ChIP-Seq_MESCs_Mouse1.94631710
9FLI1_27457419_Chip-Seq_LIVER_Mouse1.77106563
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.75543385
11ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.75361239
12SOX2_27498859_Chip-Seq_STOMACH_Mouse1.69168468
13GBX2_23144817_ChIP-Seq_PC3_Human1.65504922
14SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.61963853
15HTT_18923047_ChIP-ChIP_STHdh_Human1.60444206
16PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.60160218
17SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.57785311
18TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.56600829
19AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.55300635
20EGR1_23403033_ChIP-Seq_LIVER_Mouse1.54954014
21SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.52612334
22HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.50696010
23RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.49692014
24ESR2_21235772_ChIP-Seq_MCF-7_Human1.48584798
25SOX2_20726797_ChIP-Seq_SW620_Human1.43959178
26FOXA1_25329375_ChIP-Seq_VCAP_Human1.43707858
27FOXA1_27270436_Chip-Seq_PROSTATE_Human1.43707858
28GABP_17652178_ChIP-ChIP_JURKAT_Human1.43646949
29PCGF2_27294783_Chip-Seq_ESCs_Mouse1.43548756
30FUS_26573619_Chip-Seq_HEK293_Human1.43275235
31ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.42212107
32CDX2_22108803_ChIP-Seq_LS180_Human1.41775842
33JARID2_20075857_ChIP-Seq_MESCs_Mouse1.41627527
34MTF2_20144788_ChIP-Seq_MESCs_Mouse1.40585193
35SRY_22984422_ChIP-ChIP_TESTIS_Rat1.39238844
36BCAT_22108803_ChIP-Seq_LS180_Human1.39140611
37SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.36288365
38REST_21632747_ChIP-Seq_MESCs_Mouse1.33799855
39GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.32717779
40SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.31977056
41CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.31905514
42SRF_21415370_ChIP-Seq_HL-1_Mouse1.30678740
43SUZ12_27294783_Chip-Seq_NPCs_Mouse1.29252885
44IGF1R_20145208_ChIP-Seq_DFB_Human1.28865095
45TAF15_26573619_Chip-Seq_HEK293_Human1.28061584
46ZNF263_19887448_ChIP-Seq_K562_Human1.27388419
47AR_25329375_ChIP-Seq_VCAP_Human1.27069762
48NR3C1_23031785_ChIP-Seq_PC12_Mouse1.26232389
49PHF8_20622853_ChIP-Seq_HELA_Human1.25942705
50TP53_22573176_ChIP-Seq_HFKS_Human1.25471412
51RXR_22158963_ChIP-Seq_LIVER_Mouse1.25227174
52EZH2_27294783_Chip-Seq_ESCs_Mouse1.25107492
53NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.24670048
54LXR_22158963_ChIP-Seq_LIVER_Mouse1.24096145
55FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.23117352
56AR_20517297_ChIP-Seq_VCAP_Human1.22083734
57PIAS1_25552417_ChIP-Seq_VCAP_Human1.20938480
58FOXA1_21572438_ChIP-Seq_LNCaP_Human1.20888057
59EZH2_27304074_Chip-Seq_ESCs_Mouse1.19604591
60AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.18631856
61TOP2B_26459242_ChIP-Seq_MCF-7_Human1.18581711
62SUZ12_27294783_Chip-Seq_ESCs_Mouse1.17340111
63EZH2_18974828_ChIP-Seq_MESCs_Mouse1.17095078
64RNF2_18974828_ChIP-Seq_MESCs_Mouse1.17095078
65NFE2_27457419_Chip-Seq_LIVER_Mouse1.17077497
66AHR_22903824_ChIP-Seq_MCF-7_Human1.16140037
67SMAD3_21741376_ChIP-Seq_EPCs_Human1.16033216
68EED_16625203_ChIP-ChIP_MESCs_Mouse1.15568528
69NANOG_18555785_Chip-Seq_ESCs_Mouse1.15117286
70ER_23166858_ChIP-Seq_MCF-7_Human1.15076385
71EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.15011515
72CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.13977180
73STAT3_18555785_Chip-Seq_ESCs_Mouse1.13568171
74REST_18959480_ChIP-ChIP_MESCs_Mouse1.13139936
75EZH2_27294783_Chip-Seq_NPCs_Mouse1.12009876
76PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.11766743
77CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.11271511
78TRIM28_21343339_ChIP-Seq_HEK293_Human1.11038114
79FOXA1_25552417_ChIP-Seq_VCAP_Human1.10813308
80TCF4_22108803_ChIP-Seq_LS180_Human1.10535680
81SOX2_18555785_Chip-Seq_ESCs_Mouse1.10429047
82EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.09656118
83ERG_21242973_ChIP-ChIP_JURKAT_Human1.09453571
84CDX2_20551321_ChIP-Seq_CACO-2_Human1.08685748
85RBPJ_21746931_ChIP-Seq_IB4_Human1.08625247
86P53_22387025_ChIP-Seq_ESCs_Mouse1.08525155
87IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.08009941
88CBP_20019798_ChIP-Seq_JUKART_Human1.08009941
89ZNF217_24962896_ChIP-Seq_MCF-7_Human1.06623235
90MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.06316640
91ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.06238911
92GATA4_25053715_ChIP-Seq_YYC3_Human1.05406821
93ESR1_21235772_ChIP-Seq_MCF-7_Human1.05152252
94JARID2_20064375_ChIP-Seq_MESCs_Mouse1.05116045
95ZFP57_27257070_Chip-Seq_ESCs_Mouse1.04965391
96HNFA_21074721_ChIP-Seq_CACO-2_Human1.04789710
97PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.04419531
98FOXM1_26456572_ChIP-Seq_MCF-7_Human1.03800437
99NFYB_21822215_ChIP-Seq_K562_Human1.02661232
100SUZ12_18555785_Chip-Seq_ESCs_Mouse1.02475283
101ETV2_25802403_ChIP-Seq_MESCs_Mouse1.02147527
102BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.01786229
103CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.01779624
104TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.01139643
105SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.00908453
106SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.00904013
107CTBP1_25329375_ChIP-Seq_LNCAP_Human1.00176375
108STAT3_23295773_ChIP-Seq_U87_Human0.99856907
109FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.99539039
110STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.99485947
111KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.99378061
112CTBP2_25329375_ChIP-Seq_LNCAP_Human0.98843697
113EP300_21415370_ChIP-Seq_HL-1_Mouse0.98635489
114NFYA_21822215_ChIP-Seq_K562_Human0.97168478
115ERG_20517297_ChIP-Seq_VCAP_Human0.96559267
116E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.96111450
117CTCF_18555785_Chip-Seq_ESCs_Mouse0.95926647
118TBL1_22424771_ChIP-Seq_293T_Human0.95727426
119CMYC_18555785_Chip-Seq_ESCs_Mouse0.95274698
120EST1_17652178_ChIP-ChIP_JURKAT_Human0.95211587
121ZNF274_21170338_ChIP-Seq_K562_Hela0.95180338
122NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.95059747
123FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.94399903
124EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.93888036
125CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.92661940
126SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.92286734
127NANOG_19829295_ChIP-Seq_ESCs_Human0.91463276
128SOX2_19829295_ChIP-Seq_ESCs_Human0.91463276
129IKZF1_21737484_ChIP-ChIP_HCT116_Human0.90399035
130CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.89601748
131PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.89388494
132ARNT_22903824_ChIP-Seq_MCF-7_Human0.89336053
133CTCF_27219007_Chip-Seq_Bcells_Human0.89137875
134DROSHA_22980978_ChIP-Seq_HELA_Human0.88679077
135HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.87842779
136SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.87767874
137PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.87696318
138CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.87229875
139JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.85456784
140OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.85454606
141FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.85115545
142NCOR_22424771_ChIP-Seq_293T_Human0.83340540
143NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.83278834
144EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.83192293
145UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.82640491
146KLF5_25053715_ChIP-Seq_YYC3_Human0.82571360
147SMAD4_21799915_ChIP-Seq_A2780_Human0.82490291
148CBX2_27304074_Chip-Seq_ESCs_Mouse0.82209884
149RARG_19884340_ChIP-ChIP_MEFs_Mouse0.81867371
150OCT4_20526341_ChIP-Seq_ESCs_Human0.81212296
151TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.81045367
152FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.80938267
153SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.80916889
154NR3C1_21868756_ChIP-Seq_MCF10A_Human0.80890192
155FOXH1_21741376_ChIP-Seq_ESCs_Human0.79742318
156SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.79109884
157P300_19829295_ChIP-Seq_ESCs_Human0.78697162
158RAD21_21589869_ChIP-Seq_MESCs_Mouse0.78695275
159GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.78212946
160RNF2_27304074_Chip-Seq_ESCs_Mouse0.76849185
161SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.76340035
162CTCF_20526341_ChIP-Seq_ESCs_Human0.76323575
163P53_22127205_ChIP-Seq_FIBROBLAST_Human0.75731684
164SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.75108280

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system4.40940873
2MP0005379_endocrine/exocrine_gland_phen3.82804575
3MP0002822_catalepsy3.30016267
4MP0004270_analgesia3.19640310
5MP0002163_abnormal_gland_morphology3.08935009
6MP0004043_abnormal_pH_regulation3.05882753
7MP0010386_abnormal_urinary_bladder2.70983090
8MP0001984_abnormal_olfaction2.64531209
9MP0002734_abnormal_mechanical_nocicepti2.44712712
10MP0001944_abnormal_pancreas_morphology2.42755160
11MP0003878_abnormal_ear_physiology2.33047490
12MP0005377_hearing/vestibular/ear_phenot2.33047490
13MP0008004_abnormal_stomach_pH2.33038055
14MP0002735_abnormal_chemical_nociception2.32217244
15MP0006276_abnormal_autonomic_nervous2.19275692
16MP0002693_abnormal_pancreas_physiology2.16366493
17MP0002254_reproductive_system_inflammat2.12578221
18MP0002837_dystrophic_cardiac_calcinosis2.07342292
19MP0003806_abnormal_nucleotide_metabolis2.06718258
20MP0005365_abnormal_bile_salt2.04712537
21MP0001664_abnormal_digestion2.03670166
22MP0001968_abnormal_touch/_nociception2.02280142
23MP0002736_abnormal_nociception_after2.00344284
24MP0010234_abnormal_vibrissa_follicle1.95930396
25MP0010329_abnormal_lipoprotein_level1.95171600
26MP0001970_abnormal_pain_threshold1.88344536
27MP0001529_abnormal_vocalization1.86093237
28MP0003011_delayed_dark_adaptation1.84964808
29MP0001905_abnormal_dopamine_level1.80243313
30MP0002733_abnormal_thermal_nociception1.79016601
31MP0008875_abnormal_xenobiotic_pharmacok1.77828608
32MP0004858_abnormal_nervous_system1.74863268
33MP0001485_abnormal_pinna_reflex1.74773527
34MP0000462_abnormal_digestive_system1.72086130
35MP0000538_abnormal_urinary_bladder1.71733313
36MP0001986_abnormal_taste_sensitivity1.70605321
37MP0005645_abnormal_hypothalamus_physiol1.69595888
38MP0001440_abnormal_grooming_behavior1.65728840
39MP0002272_abnormal_nervous_system1.64295061
40MP0000013_abnormal_adipose_tissue1.63287399
41MP0002078_abnormal_glucose_homeostasis1.58178711
42MP0005085_abnormal_gallbladder_physiolo1.56946579
43MP0001756_abnormal_urination1.56383372
44MP0003186_abnormal_redox_activity1.54006774
45MP0008260_abnormal_autophagy1.50519992
46MP0000372_irregular_coat_pigmentation1.49433044
47MP0005220_abnormal_exocrine_pancreas1.48046459
48MP0001765_abnormal_ion_homeostasis1.46810610
49MP0003195_calcinosis1.44051538
50MP0002876_abnormal_thyroid_physiology1.42908559
51MP0002909_abnormal_adrenal_gland1.42438718
52MP0003787_abnormal_imprinting1.41194220
53MP0001666_abnormal_nutrient_absorption1.40248547
54MP0003880_abnormal_central_pattern1.39457049
55MP0005084_abnormal_gallbladder_morpholo1.34497089
56MP0008789_abnormal_olfactory_epithelium1.34309758
57MP0003879_abnormal_hair_cell1.30348686
58MP0002138_abnormal_hepatobiliary_system1.29078956
59MP0001542_abnormal_bone_strength1.28537294
60MP0003172_abnormal_lysosome_physiology1.25639457
61MP0002064_seizures1.25109540
62MP0005535_abnormal_body_temperature1.24937606
63MP0009643_abnormal_urine_homeostasis1.24923520
64MP0002184_abnormal_innervation1.23655214
65MP0004264_abnormal_extraembryonic_tissu1.22792102
66MP0005551_abnormal_eye_electrophysiolog1.22765287
67MP0005448_abnormal_energy_balance1.21600120
68MP0003252_abnormal_bile_duct1.20065044
69MP0002638_abnormal_pupillary_reflex1.19062149
70MP0006036_abnormal_mitochondrial_physio1.18971501
71MP0005636_abnormal_mineral_homeostasis1.18864740
72MP0009745_abnormal_behavioral_response1.18852234
73MP0003953_abnormal_hormone_level1.18817240
74MP0005174_abnormal_tail_pigmentation1.18803442
75MP0004147_increased_porphyrin_level1.18328828
76MP0002067_abnormal_sensory_capabilities1.17989449
77MP0001764_abnormal_homeostasis1.17379350
78MP0002118_abnormal_lipid_homeostasis1.17322604
79MP0003635_abnormal_synaptic_transmissio1.17275082
80MP0005332_abnormal_amino_acid1.16162743
81MP0004885_abnormal_endolymph1.16029767
82MP0003183_abnormal_peptide_metabolism1.13015848
83MP0006082_CNS_inflammation1.11324521
84MP0004742_abnormal_vestibular_system1.11092800
85MP0008877_abnormal_DNA_methylation1.10278913
86MP0002572_abnormal_emotion/affect_behav1.09686873
87MP0002277_abnormal_respiratory_mucosa1.09586478
88MP0002090_abnormal_vision1.09515986
89MP0009046_muscle_twitch1.08610421
90MP0005499_abnormal_olfactory_system1.08222979
91MP0005394_taste/olfaction_phenotype1.08222979
92MP0003329_amyloid_beta_deposits1.07748685
93MP0003283_abnormal_digestive_organ1.07661659
94MP0009780_abnormal_chondrocyte_physiolo1.06801255
95MP0005253_abnormal_eye_physiology1.06002994
96MP0004036_abnormal_muscle_relaxation1.04200295
97MP0002229_neurodegeneration1.02373189
98MP0000751_myopathy1.01448136
99MP0002751_abnormal_autonomic_nervous1.00279068
100MP0005386_behavior/neurological_phenoty0.99509623
101MP0004924_abnormal_behavior0.99509623
102MP0005408_hypopigmentation0.99025363
103MP0003122_maternal_imprinting0.98547534
104MP0004145_abnormal_muscle_electrophysio0.98282111
105MP0003315_abnormal_perineum_morphology0.98012544
106MP0001501_abnormal_sleep_pattern0.97590161
107MP0000537_abnormal_urethra_morphology0.97156440
108MP0005646_abnormal_pituitary_gland0.96990916
109MP0010678_abnormal_skin_adnexa0.96985395
110MP0004133_heterotaxia0.96659758
111MP0005410_abnormal_fertilization0.96577145
112MP0000631_abnormal_neuroendocrine_gland0.95615259
113MP0004019_abnormal_vitamin_homeostasis0.95455037
114MP0004215_abnormal_myocardial_fiber0.95442579
115MP0008872_abnormal_physiological_respon0.95233942
116MP0000639_abnormal_adrenal_gland0.93911676
117MP0002557_abnormal_social/conspecific_i0.93865779
118MP0002928_abnormal_bile_duct0.92625706
119MP0002160_abnormal_reproductive_system0.92606246
120MP0000749_muscle_degeneration0.92277476
121MP0004484_altered_response_of0.90939291
122MP0002063_abnormal_learning/memory/cond0.90433130
123MP0006035_abnormal_mitochondrial_morpho0.89898941
124MP0005248_abnormal_Harderian_gland0.89896595
125MP0001963_abnormal_hearing_physiology0.89805580
126MP0001486_abnormal_startle_reflex0.89337208
127MP0002295_abnormal_pulmonary_circulatio0.88309051
128MP0005381_digestive/alimentary_phenotyp0.88234647
129MP0009840_abnormal_foam_cell0.87127326
130MP0000747_muscle_weakness0.87079679
131MP0003866_abnormal_defecation0.86829990
132MP0000003_abnormal_adipose_tissue0.86559757
133MP0002938_white_spotting0.86515965
134MP0000015_abnormal_ear_pigmentation0.83980655
135MP0006072_abnormal_retinal_apoptosis0.82332517
136MP0003633_abnormal_nervous_system0.81012557
137MP0000778_abnormal_nervous_system0.80878350
138MP0005058_abnormal_lysosome_morphology0.80536672
139MP0002882_abnormal_neuron_morphology0.80496260
140MP0001188_hyperpigmentation0.80432699
141MP0004142_abnormal_muscle_tone0.79714730
142MP0005075_abnormal_melanosome_morpholog0.79078282
143MP0003634_abnormal_glial_cell0.77512600
144MP0000230_abnormal_systemic_arterial0.77223959
145MP0005319_abnormal_enzyme/_coenzyme0.77057780
146MP0004085_abnormal_heartbeat0.75932088
147MP0003646_muscle_fatigue0.74651739
148MP0002971_abnormal_brown_adipose0.73642772
149MP0000427_abnormal_hair_cycle0.67350532
150MP0009642_abnormal_blood_homeostasis0.65536977
151MP0005452_abnormal_adipose_tissue0.63183833
152MP0002136_abnormal_kidney_physiology0.62734019

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)4.95972374
2Acute necrotizing encephalopathy (HP:0006965)4.68440514
3Abnormal mitochondria in muscle tissue (HP:0008316)4.28249505
4Acute encephalopathy (HP:0006846)4.08770524
5Progressive macrocephaly (HP:0004481)3.97242245
6Hypothermia (HP:0002045)3.87342560
7Mitochondrial inheritance (HP:0001427)3.78923629
8Pheochromocytoma (HP:0002666)3.56510854
9Myokymia (HP:0002411)3.53157434
10Neuroendocrine neoplasm (HP:0100634)3.28715903
11Congenital malformation of the right heart (HP:0011723)3.23047184
12Double outlet right ventricle (HP:0001719)3.23047184
13Increased CSF lactate (HP:0002490)3.22272698
14Hyperactive renin-angiotensin system (HP:0000841)3.18809776
15Gout (HP:0001997)3.17593707
16Hepatocellular necrosis (HP:0001404)3.17042685
17Increased CSF protein (HP:0002922)3.05674041
18Large for gestational age (HP:0001520)3.02159870
19Metabolic alkalosis (HP:0200114)3.01614098
20Hyperglycemia (HP:0003074)2.99229439
21Hepatic necrosis (HP:0002605)2.99145732
22Vascular calcification (HP:0004934)2.94690301
23Ketoacidosis (HP:0001993)2.91255682
24Limb dystonia (HP:0002451)2.86892487
253-Methylglutaconic aciduria (HP:0003535)2.85302612
26Palpitations (HP:0001962)2.84005139
27Progressive neurologic deterioration (HP:0002344)2.82522705
28Abnormality of vitamin metabolism (HP:0100508)2.79965949
29Hypoglycemic coma (HP:0001325)2.77537301
30Hypomagnesemia (HP:0002917)2.70992897
31Intestinal atresia (HP:0011100)2.68215775
32Respiratory failure (HP:0002878)2.66232605
33Abnormality of magnesium homeostasis (HP:0004921)2.65748391
34Ileus (HP:0002595)2.63791435
35Cerebral edema (HP:0002181)2.61779000
36Retinal dysplasia (HP:0007973)2.57117251
37Hypokinesia (HP:0002375)2.56585622
38Hyperinsulinemic hypoglycemia (HP:0000825)2.55998050
39Hypokalemic alkalosis (HP:0001949)2.49485283
40Vacuolated lymphocytes (HP:0001922)2.48988506
41Abnormality of chloride homeostasis (HP:0011422)2.45720721
42Cardiovascular calcification (HP:0011915)2.44661871
43Postural tremor (HP:0002174)2.41979985
44Increased circulating renin level (HP:0000848)2.41462001
45Lactic acidosis (HP:0003128)2.40968174
46Hyperaldosteronism (HP:0000859)2.39009854
47Late onset (HP:0003584)2.33890198
48Nuclear cataract (HP:0100018)2.31768245
49Glycosuria (HP:0003076)2.30059835
50Abnormality of urine glucose concentration (HP:0011016)2.30059835
51Ketosis (HP:0001946)2.29440900
52Abnormality of renal resorption (HP:0011038)2.27812203
53Optic disc pallor (HP:0000543)2.25832043
54Leukodystrophy (HP:0002415)2.25071746
55Abnormality of renin-angiotensin system (HP:0000847)2.24777628
56Syncope (HP:0001279)2.23923288
57Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.23383454
58Methylmalonic aciduria (HP:0012120)2.22918600
59Hypoalbuminemia (HP:0003073)2.22293159
60Abnormal albumin level (HP:0012116)2.22293159
61Renal salt wasting (HP:0000127)2.20974913
62Generalized aminoaciduria (HP:0002909)2.19060204
63Abnormality of glycolipid metabolism (HP:0010969)2.18142586
64Abnormality of liposaccharide metabolism (HP:0010968)2.18142586
65Abnormality of glycosphingolipid metabolism (HP:0004343)2.18142586
66Increased purine levels (HP:0004368)2.16624886
67Hyperuricemia (HP:0002149)2.16624886
68Pancreatic fibrosis (HP:0100732)2.16272355
69Hypokalemia (HP:0002900)2.16232694
70Exercise intolerance (HP:0003546)2.14657605
71Lethargy (HP:0001254)2.13456475
72Tubular atrophy (HP:0000092)2.11044433
73Aplasia/hypoplasia of the uterus (HP:0008684)2.10261834
74Pancreatic cysts (HP:0001737)2.08833098
75Ventricular fibrillation (HP:0001663)2.08689192
76Abnormality of vitamin B metabolism (HP:0004340)2.08457337
77Increased hepatocellular lipid droplets (HP:0006565)2.08432442
78Lipid accumulation in hepatocytes (HP:0006561)2.07057685
79Hemiparesis (HP:0001269)2.06185671
80Hypoglycemic seizures (HP:0002173)2.05063766
81Hyperphosphatemia (HP:0002905)2.04291023
82Abnormality of the renal cortex (HP:0011035)2.03887403
83Abnormality of the vitamin B12 metabolism (HP:0004341)2.03878158
84Abnormality of renal excretion (HP:0011036)2.03861488
85Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.02703429
86Abnormality of mucopolysaccharide metabolism (HP:0011020)2.02410767
87Abnormality of polysaccharide metabolism (HP:0011012)2.02410767
88Abnormality of glycosaminoglycan metabolism (HP:0004371)2.02410767
89Exocrine pancreatic insufficiency (HP:0001738)2.01585118
90True hermaphroditism (HP:0010459)2.01379491
91Chronic bronchitis (HP:0004469)2.00357251
92Rhinitis (HP:0012384)1.99817922
93Insulin-resistant diabetes mellitus (HP:0000831)1.99253842
94Conjunctival hamartoma (HP:0100780)1.98580203
95Medial flaring of the eyebrow (HP:0010747)1.98255500
96Renal Fanconi syndrome (HP:0001994)1.98016441
97Abnormality of glycolysis (HP:0004366)1.97231389
98Increased serum pyruvate (HP:0003542)1.97231389
99Genital tract atresia (HP:0001827)1.95994150
100Atonic seizures (HP:0010819)1.95891262
101Gait imbalance (HP:0002141)1.95754054
102Abnormal tarsal ossification (HP:0008369)1.95128615
103Steatorrhea (HP:0002570)1.94231908
104Hyperphosphaturia (HP:0003109)1.93694869
105Agitation (HP:0000713)1.93605687
106Autoamputation (HP:0001218)1.92272760
107Vaginal atresia (HP:0000148)1.92133819
108Abnormality of midbrain morphology (HP:0002418)1.92032975
109Molar tooth sign on MRI (HP:0002419)1.92032975
110Myotonia (HP:0002486)1.91908103
111Proximal tubulopathy (HP:0000114)1.91795530
112Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.91469700
113Congenital sensorineural hearing impairment (HP:0008527)1.91060284
114Mucopolysacchariduria (HP:0008155)1.89937485
115Urinary glycosaminoglycan excretion (HP:0003541)1.89937485
116Right ventricular cardiomyopathy (HP:0011663)1.89927590
117Congenital primary aphakia (HP:0007707)1.89390450
118Decreased circulating renin level (HP:0003351)1.88548888
119Abnormal respiratory motile cilium morphology (HP:0005938)1.87774931
120Abnormal respiratory epithelium morphology (HP:0012253)1.87774931
121Abnormal ciliary motility (HP:0012262)1.87352603
122Goiter (HP:0000853)1.86947962
123Abnormal autonomic nervous system physiology (HP:0012332)1.86827270
124Emotional lability (HP:0000712)1.86668281
125Nephrogenic diabetes insipidus (HP:0009806)1.84924004
126Decreased activity of mitochondrial respiratory chain (HP:0008972)1.84499024
127Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.84499024
128CNS demyelination (HP:0007305)1.83460428
129Polyuria (HP:0000103)1.83411639
130Muscle fiber splitting (HP:0003555)1.83342157
131Severe visual impairment (HP:0001141)1.82503589
132Dysautonomia (HP:0002459)1.82355984
133Hyperthyroidism (HP:0000836)1.82153964
134Myopathic facies (HP:0002058)1.81758836
135Exertional dyspnea (HP:0002875)1.81443991
136Hypoplasia of the fovea (HP:0007750)1.80704387
137Aplasia/Hypoplasia of the fovea (HP:0008060)1.80704387
138Nephronophthisis (HP:0000090)1.80676386
139Abnormal urine output (HP:0012590)1.80672458
140Increased serum lactate (HP:0002151)1.79619734
141Alkalosis (HP:0001948)1.79539256
142Congenital ichthyosiform erythroderma (HP:0007431)1.79306249
143Hypotension (HP:0002615)1.77369068
144Abnormal respiratory motile cilium physiology (HP:0012261)1.76779613
145Focal motor seizures (HP:0011153)1.75123748
146Increased intramyocellular lipid droplets (HP:0012240)1.74803451
147Prolonged QT interval (HP:0001657)1.74793495
148X-linked dominant inheritance (HP:0001423)1.72532073
149Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.71213019
150Ankle clonus (HP:0011448)1.70975237
151Adrenal overactivity (HP:0002717)1.70713948
152Abnormality of dicarboxylic acid metabolism (HP:0010995)1.70390272
153Dicarboxylic aciduria (HP:0003215)1.70390272
154Sudden death (HP:0001699)1.68365379
155Methylmalonic acidemia (HP:0002912)1.68290758
156Abnormality of calcium-phosphate metabolism (HP:0100530)1.67399056
157Septate vagina (HP:0001153)1.67274316
158Sensory axonal neuropathy (HP:0003390)1.65548405
159Increased muscle lipid content (HP:0009058)1.65407251
160Abnormal urine phosphate concentration (HP:0012599)1.64065673

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ARAF3.67472697
2EPHA23.33799369
3STK392.97333701
4WNK42.85169517
5NME12.76938706
6MST42.69537763
7OXSR12.68797962
8AKT32.32145548
9MAP4K22.28081070
10MAP2K22.25108691
11CASK2.22882461
12WNK32.08919319
13GRK52.04299620
14MAPK151.97234224
15MAP3K121.96805576
16BRAF1.96331482
17FGFR21.93689261
18LIMK11.84191309
19LMTK21.83662638
20NTRK11.79949241
21MAP3K21.77307347
22FRK1.71398305
23ACVR1B1.65707273
24MYLK1.63620246
25CAMK2D1.58159587
26CAMK2B1.52590175
27PHKG11.49528162
28PHKG21.49528162
29STK38L1.46636852
30MAPKAPK51.44324958
31CAMK2G1.42768082
32STK161.42379269
33TESK11.41569338
34BCR1.41418957
35TRIM281.35352123
36PNCK1.33328651
37PIK3CA1.33169310
38SGK2231.31757439
39SGK4941.31757439
40MST1R1.23895776
41KSR21.17645330
42EIF2AK31.16865639
43MAP2K11.15860671
44PDK21.15245703
45EIF2AK11.13533932
46STK31.11111845
47PIM21.10749039
48TRPM71.10580244
49OBSCN1.05840690
50PDK31.04602419
51PDK41.04602419
52PRKCI1.03958292
53PRKCE1.02835134
54NLK1.01800739
55FER0.98956497
56FGFR30.98027130
57EPHA30.96680929
58MET0.94955419
59CSNK1G30.93575524
60MAP3K90.90185090
61TNIK0.87498948
62MAP3K30.84591675
63BMPR20.83390879
64PRKG20.82954972
65TESK20.82188078
66CAMKK20.81153919
67DAPK20.79775407
68GRK70.79080732
69ZAK0.76754784
70PINK10.76715106
71PAK30.75966071
72MAPK130.75207307
73BCKDK0.74799634
74CAMK2A0.73114587
75CSNK1G20.71450609
76MINK10.71256043
77PTK2B0.71045492
78TNK20.69945153
79NTRK30.67927124
80DAPK30.65902917
81MARK10.65240522
82PRKG10.64782440
83DAPK10.64643036
84CSNK1G10.63904169
85WNK10.63835569
86MAP2K70.63483230
87STK240.62312394
88NEK10.60245218
89ERBB40.57382931
90BMPR1B0.56358051
91DYRK20.56256583
92ERBB30.55428798
93PLK20.55045463
94TAOK10.53522741
95MAP2K40.53298700
96TLK10.52860143
97RIPK10.52290819
98PRKCG0.52107842
99PRKD30.51700682
100PDPK10.50275827
101ABL20.50067529
102IRAK10.48984385
103PRKAA20.48657381
104STK40.48133248
105ADRBK20.46845878
106PRKACA0.44649200
107CDK140.43913531
108AKT20.43754190
109ROCK20.43430399
110ADRBK10.42254023
111CDK50.41423704
112MAPKAPK30.41249955
113IKBKB0.40470551
114SGK20.40395202
115MATK0.40287319
116CSNK1A1L0.39649887
117INSRR0.39446334
118YES10.39299710
119ROCK10.38999521
120RPS6KA20.38952243
121MAP2K60.38884995
122CSNK1A10.38375117
123EPHB20.38155075
124PIK3CG0.37522902
125GRK10.37403894
126MUSK0.36540029
127MAP3K40.36299617
128PRKCQ0.35898575
129STK110.35498472
130PRKAA10.35222190
131MAP3K10.35106162
132PRKCA0.34422180
133PKN10.34371525
134MKNK20.31278881
135HIPK20.31176414
136ILK0.29737530
137PAK40.28096821

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001904.48002595
2Parkinsons disease_Homo sapiens_hsa050123.66256588
3Sulfur metabolism_Homo sapiens_hsa009203.14775373
4Collecting duct acid secretion_Homo sapiens_hsa049663.03824892
5Alzheimers disease_Homo sapiens_hsa050102.82877547
6Huntingtons disease_Homo sapiens_hsa050162.47133943
7Vibrio cholerae infection_Homo sapiens_hsa051102.16100908
8Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.08253700
9Synaptic vesicle cycle_Homo sapiens_hsa047211.99493154
10Cardiac muscle contraction_Homo sapiens_hsa042601.96743026
11Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.92062540
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.85524453
13Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.82892634
14Nitrogen metabolism_Homo sapiens_hsa009101.81955036
15Protein export_Homo sapiens_hsa030601.76364119
16Olfactory transduction_Homo sapiens_hsa047401.73335970
17Maturity onset diabetes of the young_Homo sapiens_hsa049501.71806219
18Mineral absorption_Homo sapiens_hsa049781.68566015
19Proteasome_Homo sapiens_hsa030501.53568325
20Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.53206659
21Regulation of autophagy_Homo sapiens_hsa041401.46412829
22Pyruvate metabolism_Homo sapiens_hsa006201.46103544
23Histidine metabolism_Homo sapiens_hsa003401.45987883
24Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.44302015
25Insulin secretion_Homo sapiens_hsa049111.41260475
26Circadian rhythm_Homo sapiens_hsa047101.36757411
27Fatty acid elongation_Homo sapiens_hsa000621.27812567
28Pentose and glucuronate interconversions_Homo sapiens_hsa000401.26250481
29Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.26079733
30Arginine biosynthesis_Homo sapiens_hsa002201.20433398
31Fructose and mannose metabolism_Homo sapiens_hsa000511.19667414
32Sphingolipid metabolism_Homo sapiens_hsa006001.18498789
33Tryptophan metabolism_Homo sapiens_hsa003801.18226380
34Linoleic acid metabolism_Homo sapiens_hsa005911.17449613
35Selenocompound metabolism_Homo sapiens_hsa004501.16731858
36alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.16440559
37Pancreatic secretion_Homo sapiens_hsa049721.12822683
38Chemical carcinogenesis_Homo sapiens_hsa052041.12216855
39Butanoate metabolism_Homo sapiens_hsa006501.11996508
40Taste transduction_Homo sapiens_hsa047421.10641398
41Propanoate metabolism_Homo sapiens_hsa006401.09622890
42Ether lipid metabolism_Homo sapiens_hsa005651.09284354
43Gastric acid secretion_Homo sapiens_hsa049711.07244179
44Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.04954873
45Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.04237908
46Primary bile acid biosynthesis_Homo sapiens_hsa001201.03922614
47Arachidonic acid metabolism_Homo sapiens_hsa005901.02895667
48Retinol metabolism_Homo sapiens_hsa008301.02875510
49Tight junction_Homo sapiens_hsa045301.01473160
50Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.00123536
51Fat digestion and absorption_Homo sapiens_hsa049751.00096920
52Serotonergic synapse_Homo sapiens_hsa047260.99847813
53Glycosaminoglycan degradation_Homo sapiens_hsa005310.99433566
54Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.98620452
55Arginine and proline metabolism_Homo sapiens_hsa003300.97964706
56Glutathione metabolism_Homo sapiens_hsa004800.96085053
57Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.95692451
58Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.95325098
59Folate biosynthesis_Homo sapiens_hsa007900.94579732
60Dopaminergic synapse_Homo sapiens_hsa047280.93809032
61GABAergic synapse_Homo sapiens_hsa047270.91385269
62SNARE interactions in vesicular transport_Homo sapiens_hsa041300.90415555
63Caffeine metabolism_Homo sapiens_hsa002320.88602335
64Steroid biosynthesis_Homo sapiens_hsa001000.87503325
65beta-Alanine metabolism_Homo sapiens_hsa004100.86987159
66Glycerophospholipid metabolism_Homo sapiens_hsa005640.86104627
67Amphetamine addiction_Homo sapiens_hsa050310.86039081
68Vitamin digestion and absorption_Homo sapiens_hsa049770.84450992
69Type I diabetes mellitus_Homo sapiens_hsa049400.83862302
70Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.83858149
71Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.82852994
72Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.82555852
73Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.80784765
74Cocaine addiction_Homo sapiens_hsa050300.79173572
75Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.77079376
76Circadian entrainment_Homo sapiens_hsa047130.76040766
77Metabolic pathways_Homo sapiens_hsa011000.76033195
78Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.75964242
79Thyroid hormone synthesis_Homo sapiens_hsa049180.75571925
80Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.75466720
81Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.74435686
82Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.74188076
83Phototransduction_Homo sapiens_hsa047440.73442851
84Salivary secretion_Homo sapiens_hsa049700.72172234
85Tyrosine metabolism_Homo sapiens_hsa003500.72078483
86Starch and sucrose metabolism_Homo sapiens_hsa005000.71657303
87Fatty acid metabolism_Homo sapiens_hsa012120.70426719
88Phenylalanine metabolism_Homo sapiens_hsa003600.70335502
89Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.69637172
90Cholinergic synapse_Homo sapiens_hsa047250.69314908
91Renin-angiotensin system_Homo sapiens_hsa046140.66885747
92Steroid hormone biosynthesis_Homo sapiens_hsa001400.58182477
93Morphine addiction_Homo sapiens_hsa050320.57662196
94Glycerolipid metabolism_Homo sapiens_hsa005610.56014287
95Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.55787057
96Glucagon signaling pathway_Homo sapiens_hsa049220.55447038
97Vascular smooth muscle contraction_Homo sapiens_hsa042700.55170499
98Carbon metabolism_Homo sapiens_hsa012000.54849079
99Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54667661
100Bile secretion_Homo sapiens_hsa049760.53815392
101Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.51208827
102Rheumatoid arthritis_Homo sapiens_hsa053230.50904491
103Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.50606885
104Galactose metabolism_Homo sapiens_hsa000520.50075555
105Glutamatergic synapse_Homo sapiens_hsa047240.48491801
106Renin secretion_Homo sapiens_hsa049240.45537769
107Protein digestion and absorption_Homo sapiens_hsa049740.44949643
108Other glycan degradation_Homo sapiens_hsa005110.44441884
109N-Glycan biosynthesis_Homo sapiens_hsa005100.44107835
110Complement and coagulation cascades_Homo sapiens_hsa046100.43818998
111Drug metabolism - other enzymes_Homo sapiens_hsa009830.42733569
112Lysosome_Homo sapiens_hsa041420.42065403
113Vitamin B6 metabolism_Homo sapiens_hsa007500.41644080
114RNA polymerase_Homo sapiens_hsa030200.41489417
115Peroxisome_Homo sapiens_hsa041460.41362155
116Nicotine addiction_Homo sapiens_hsa050330.40928751
1172-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.40248702
118Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.39505092
119ABC transporters_Homo sapiens_hsa020100.39346726
120Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.38321898
121Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.38198279
122Long-term potentiation_Homo sapiens_hsa047200.37657777
123Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.34735939
124PPAR signaling pathway_Homo sapiens_hsa033200.34678278
125Long-term depression_Homo sapiens_hsa047300.34583059
126Gap junction_Homo sapiens_hsa045400.34377009
127Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.31117596
128Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.30447234
129Fatty acid degradation_Homo sapiens_hsa000710.30130491
130Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.29955545

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »