CXORF49B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1male meiosis (GO:0007140)9.21317011
2synapsis (GO:0007129)6.64479241
3positive regulation of catecholamine secretion (GO:0033605)6.63555156
4binding of sperm to zona pellucida (GO:0007339)6.55342324
5chromosome organization involved in meiosis (GO:0070192)5.89204228
6meiotic nuclear division (GO:0007126)5.86106664
7piRNA metabolic process (GO:0034587)5.83214095
8synaptonemal complex assembly (GO:0007130)5.58905905
9male meiosis I (GO:0007141)5.57474949
10regulation of phosphoprotein phosphatase activity (GO:0043666)5.57440597
11spermatid development (GO:0007286)5.50340523
12positive regulation of synaptic transmission, dopaminergic (GO:0032226)5.49020008
13acrosome reaction (GO:0007340)5.42429721
14meiosis I (GO:0007127)5.12908156
15synaptonemal complex organization (GO:0070193)5.10290627
16multicellular organism reproduction (GO:0032504)5.02756961
17sperm-egg recognition (GO:0035036)4.97935131
18DNA synthesis involved in DNA repair (GO:0000731)4.79547122
19DNA methylation involved in gamete generation (GO:0043046)4.55868088
20negative regulation of macroautophagy (GO:0016242)4.44239264
21DNA replication initiation (GO:0006270)4.31642577
22regulation of oxidative phosphorylation (GO:0002082)4.30957098
23cell-cell recognition (GO:0009988)4.28406749
24sperm motility (GO:0030317)4.28025662
25diterpenoid biosynthetic process (GO:0016102)4.22427855
26histone H3-K9 demethylation (GO:0033169)4.03291818
27regulation of oxidative stress-induced neuron death (GO:1903203)4.02568879
28histone exchange (GO:0043486)3.99178882
29ribosome assembly (GO:0042255)3.94979333
30meiotic cell cycle process (GO:1903046)3.81749869
31regulation of interleukin-5 production (GO:0032674)3.81056578
32motile cilium assembly (GO:0044458)3.79628118
33potassium ion export (GO:0071435)3.77520105
34response to acidic pH (GO:0010447)3.74373747
35TOR signaling (GO:0031929)3.74111501
36regulation of meiosis I (GO:0060631)3.74025558
37germ cell development (GO:0007281)3.68631847
38notochord development (GO:0030903)3.66997318
39polyamine biosynthetic process (GO:0006596)3.62885300
40proteasome assembly (GO:0043248)3.62769423
41tongue development (GO:0043586)3.60713240
42rRNA methylation (GO:0031167)3.59924418
43activation of protein kinase B activity (GO:0032148)3.59699001
44rRNA modification (GO:0000154)3.58480825
45single fertilization (GO:0007338)3.57243392
46terpenoid biosynthetic process (GO:0016114)3.55179208
47N-terminal protein amino acid acetylation (GO:0006474)3.49413768
48regulation of autophagic vacuole assembly (GO:2000785)3.48573764
49regulation of cellular respiration (GO:0043457)3.44718385
50fertilization (GO:0009566)3.31245296
51regulation of hydrogen peroxide-induced cell death (GO:1903205)3.28720842
52de novo posttranslational protein folding (GO:0051084)3.27934562
53de novo protein folding (GO:0006458)3.26034243
54reproduction (GO:0000003)3.20966138
55relaxation of smooth muscle (GO:0044557)3.20270459
56sister chromatid cohesion (GO:0007062)3.18888881
57negative regulation of hydrogen peroxide-induced cell death (GO:1903206)3.18251568
58organic cation transport (GO:0015695)3.12482619
59histone H3-K36 demethylation (GO:0070544)3.12299871
60mRNA cleavage (GO:0006379)3.12165937
61negative regulation of cardiac muscle cell apoptotic process (GO:0010667)3.12014592
62oocyte development (GO:0048599)3.06291520
63oogenesis (GO:0048477)3.03357374
64negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)3.01590275
65cellular process involved in reproduction in multicellular organism (GO:0022412)2.98669219
66poly(A)+ mRNA export from nucleus (GO:0016973)2.98301287
67female gamete generation (GO:0007292)2.97661690
68morphogenesis of embryonic epithelium (GO:0016331)2.97560710
69fusion of sperm to egg plasma membrane (GO:0007342)2.93915067
70centriole assembly (GO:0098534)2.92073365
71DNA double-strand break processing (GO:0000729)2.89123630
72regulation of cardioblast differentiation (GO:0051890)2.87835340
73male sex determination (GO:0030238)2.86879920
74regulation of vacuole organization (GO:0044088)2.86770070
75negative regulation of response to reactive oxygen species (GO:1901032)2.83633370
76epithelial cilium movement (GO:0003351)2.81862942
77Leydig cell differentiation (GO:0033327)2.78760411
78regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.78554291
79ectoderm development (GO:0007398)2.74398353
80regulation of keratinocyte proliferation (GO:0010837)2.73243502
81keratinocyte development (GO:0003334)2.73235983
82genitalia morphogenesis (GO:0035112)2.71208603
83DNA replication-dependent nucleosome assembly (GO:0006335)2.66173816
84DNA replication-dependent nucleosome organization (GO:0034723)2.66173816
85protein-DNA complex disassembly (GO:0032986)2.61252826
86nucleosome disassembly (GO:0006337)2.61252826
87telomere maintenance (GO:0000723)2.61195499
88regulation of acrosome reaction (GO:0060046)2.56960928
89protein polymerization (GO:0051258)2.56781816
90chromosome organization (GO:0051276)2.56511341
91telomere organization (GO:0032200)2.56407474
92regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.55557698
93glycogen metabolic process (GO:0005977)2.54676773
94positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.51234023
95hippo signaling (GO:0035329)2.51025014
96glucan metabolic process (GO:0044042)2.49817400
97cellular glucan metabolic process (GO:0006073)2.49817400
98cellular response to pH (GO:0071467)2.46512394
99negative regulation of retinoic acid receptor signaling pathway (GO:0048387)14.5074166
100regulation of retinoic acid receptor signaling pathway (GO:0048385)12.2590505

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse8.24829757
2BP1_19119308_ChIP-ChIP_Hs578T_Human5.02524772
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.38546000
4IGF1R_20145208_ChIP-Seq_DFB_Human4.32707093
5E2F7_22180533_ChIP-Seq_HELA_Human3.74490607
6AR_21909140_ChIP-Seq_LNCAP_Human3.39486789
7ESR1_20079471_ChIP-ChIP_T-47D_Human3.09057976
8TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.72316292
9NOTCH1_21737748_ChIP-Seq_TLL_Human2.60462597
10KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.57946445
11VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human2.47355904
12CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.29661777
13FOXM1_23109430_ChIP-Seq_U2OS_Human2.27708254
14MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.26303718
15TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.16086317
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.14650198
17HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.03950850
18FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.01711207
19MYC_18555785_ChIP-Seq_MESCs_Mouse1.86312828
20CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.82700476
21GABP_17652178_ChIP-ChIP_JURKAT_Human1.77425760
22ZNF263_19887448_ChIP-Seq_K562_Human1.66963634
23ETS1_20019798_ChIP-Seq_JURKAT_Human1.59832773
24RAC3_21632823_ChIP-Seq_H3396_Human1.59585458
25GABP_19822575_ChIP-Seq_HepG2_Human1.58948992
26ELF5_23300383_ChIP-Seq_T47D_Human1.56243617
27NANOG_20526341_ChIP-Seq_ESCs_Human1.50196253
28TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.48968796
29DCP1A_22483619_ChIP-Seq_HELA_Human1.48326322
30HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.47833390
31SMC4_20622854_ChIP-Seq_HELA_Human1.46869493
32ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.44920571
33ZNF274_21170338_ChIP-Seq_K562_Hela1.41522124
34RBPJ_21746931_ChIP-Seq_IB4_Human1.40916163
35SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.40191915
36ERA_21632823_ChIP-Seq_H3396_Human1.36150038
37MYC_19829295_ChIP-Seq_ESCs_Human1.33790241
38RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.31537916
39ETV1_20927104_ChIP-Seq_GIST48_Human1.29981840
40HOXB7_26014856_ChIP-Seq_BT474_Human1.29833265
41AHR_22903824_ChIP-Seq_MCF-7_Human1.29264400
42PKCTHETA_26484144_Chip-Seq_BREAST_Human1.25661425
43LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.24613985
44OCT4_20526341_ChIP-Seq_ESCs_Human1.24428979
45PHF8_20622853_ChIP-Seq_HELA_Human1.23347251
46TBL1_22424771_ChIP-Seq_293T_Human1.22763542
47KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.20809938
48KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.20809938
49KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.20809938
50MYC_18358816_ChIP-ChIP_MESCs_Mouse1.20659603
51CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.19657130
52PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.16817854
53SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.14267532
54AR_21572438_ChIP-Seq_LNCaP_Human1.13071512
55CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.12667137
56MYC_19030024_ChIP-ChIP_MESCs_Mouse1.11844280
57CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.09937251
58GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.09787595
59CTCF_20526341_ChIP-Seq_ESCs_Human1.09221223
60KDM5A_27292631_Chip-Seq_BREAST_Human1.09037157
61SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.09027973
62E2F1_20622854_ChIP-Seq_HELA_Human1.08496813
63SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.07602860
64RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.07315196
65PHF8_20622854_ChIP-Seq_HELA_Human1.07259194
66DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.06002460
67E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.04725626
68CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.04551086
69RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.04174671
70NFYB_21822215_ChIP-Seq_K562_Human1.03651141
71GATA6_21074721_ChIP-Seq_CACO-2_Human1.03596284
72MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.02600961
73IRF1_19129219_ChIP-ChIP_H3396_Human1.00965294
74ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.00075778
75KLF5_20875108_ChIP-Seq_MESCs_Mouse0.98807743
76SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.98668522
77HNFA_21074721_ChIP-Seq_CACO-2_Human0.98298520
78CTCF_27219007_Chip-Seq_Bcells_Human0.98090687
79WDR5_24793694_ChIP-Seq_LNCAP_Human0.97573951
80P300_27268052_Chip-Seq_Bcells_Human0.95080982
81ATF3_27146783_Chip-Seq_COLON_Human0.94974777
82FOXH1_21741376_ChIP-Seq_EPCs_Human0.93691398
83KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.93303972
84TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.92572039
85THAP11_20581084_ChIP-Seq_MESCs_Mouse0.92300690
86BCOR_27268052_Chip-Seq_Bcells_Human0.90941985
87P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.89168558
88EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.89019276
89YY1_22570637_ChIP-Seq_MALME-3M_Human0.86967957
90CTBP1_25329375_ChIP-Seq_LNCAP_Human0.86558375
91KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.85674795
92VDR_23849224_ChIP-Seq_CD4+_Human0.84679708
93ARNT_22903824_ChIP-Seq_MCF-7_Human0.84367699
94PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.84292319
95P68_20966046_ChIP-Seq_HELA_Human0.84277935
96PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.83386688
97FOXH1_21741376_ChIP-Seq_ESCs_Human0.82014594
98EST1_17652178_ChIP-ChIP_JURKAT_Human0.82000466
99CBX2_22325352_ChIP-Seq_293T-Rex_Human0.80554834
100PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.80107106

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization5.35777036
2MP0003315_abnormal_perineum_morphology4.33659938
3MP0003693_abnormal_embryo_hatching3.61095185
4MP0008004_abnormal_stomach_pH3.46641946
5MP0002160_abnormal_reproductive_system3.36284474
6MP0008877_abnormal_DNA_methylation2.95876374
7MP0001929_abnormal_gametogenesis2.94610139
8MP0003718_maternal_effect2.88130541
9MP0002210_abnormal_sex_determination2.71963577
10MP0003698_abnormal_male_reproductive2.65909392
11MP0010234_abnormal_vibrissa_follicle2.64269325
12MP0002163_abnormal_gland_morphology2.41679606
13MP0002796_impaired_skin_barrier2.16999366
14MP0004381_abnormal_hair_follicle2.15609312
15MP0005360_urolithiasis2.13557355
16MP0002132_abnormal_respiratory_system2.13305525
17MP0000569_abnormal_digit_pigmentation2.11934113
18MP0003806_abnormal_nucleotide_metabolis2.06185629
19MP0008058_abnormal_DNA_repair2.06051069
20MP0000537_abnormal_urethra_morphology1.99756540
21MP0001145_abnormal_male_reproductive1.96847100
22MP0000653_abnormal_sex_gland1.95500563
23MP0003077_abnormal_cell_cycle1.95459036
24MP0005379_endocrine/exocrine_gland_phen1.95378303
25MP0001849_ear_inflammation1.85015943
26MP0010094_abnormal_chromosome_stability1.84652941
27MP0004957_abnormal_blastocyst_morpholog1.84063157
28MP0001348_abnormal_lacrimal_gland1.83717585
29MP0001188_hyperpigmentation1.64649357
30MP0002161_abnormal_fertility/fecundity1.64457628
31MP0004264_abnormal_extraembryonic_tissu1.62900345
32MP0005499_abnormal_olfactory_system1.62873494
33MP0005394_taste/olfaction_phenotype1.62873494
34MP0010678_abnormal_skin_adnexa1.59677952
35MP0003136_yellow_coat_color1.59156686
36MP0003936_abnormal_reproductive_system1.49957886
37MP0005389_reproductive_system_phenotype1.49724306
38MP0008995_early_reproductive_senescence1.44359434
39MP0005647_abnormal_sex_gland1.41682739
40MP0010368_abnormal_lymphatic_system1.40010095
41MP0001664_abnormal_digestion1.39060112
42MP0005058_abnormal_lysosome_morphology1.37048611
43MP0002233_abnormal_nose_morphology1.33111133
44MP0005501_abnormal_skin_physiology1.32047630
45MP0000762_abnormal_tongue_morphology1.29448281
46MP0002138_abnormal_hepatobiliary_system1.28307814
47MP0004272_abnormal_basement_membrane1.28272874
48MP0002254_reproductive_system_inflammat1.27685870
49MP0003111_abnormal_nucleus_morphology1.27574400
50MP0009697_abnormal_copulation1.26259869
51MP0000678_abnormal_parathyroid_gland1.26187276
52MP0005395_other_phenotype1.26108198
53MP0003045_fibrosis1.25893771
54MP0001984_abnormal_olfaction1.18894514
55MP0006036_abnormal_mitochondrial_physio1.18877088
56MP0001730_embryonic_growth_arrest1.17754991
57MP0010030_abnormal_orbit_morphology1.16882049
58MP0005187_abnormal_penis_morphology1.11220133
59MP0000627_abnormal_mammary_gland1.10126752
60MP0005171_absent_coat_pigmentation1.09335896
61MP0003699_abnormal_female_reproductive1.07600039
62MP0000462_abnormal_digestive_system1.05519432
63MP0002089_abnormal_postnatal_growth/wei1.04966505
64MP0006035_abnormal_mitochondrial_morpho1.01026612
65MP0000470_abnormal_stomach_morphology0.96990822
66MP0008789_abnormal_olfactory_epithelium0.96852643
67MP0003941_abnormal_skin_development0.95197975
68MP0003385_abnormal_body_wall0.94439923
69MP0000647_abnormal_sebaceous_gland0.94195654
70MP0005174_abnormal_tail_pigmentation0.92867517
71MP0008932_abnormal_embryonic_tissue0.91515207
72MP0001672_abnormal_embryogenesis/_devel0.91327130
73MP0005380_embryogenesis_phenotype0.91327130
74MP0005646_abnormal_pituitary_gland0.88151293
75MP0002127_abnormal_cardiovascular_syste0.87778220
76MP0003786_premature_aging0.87087778
77MP0001119_abnormal_female_reproductive0.86460883
78MP0000477_abnormal_intestine_morphology0.85691720
79MP0000015_abnormal_ear_pigmentation0.83542473
80MP0003453_abnormal_keratinocyte_physiol0.83382331
81MP0005409_darkened_coat_color0.81129248
82MP0003646_muscle_fatigue0.80563105
83MP0001905_abnormal_dopamine_level0.79990787
84MP0006138_congestive_heart_failure0.79436828
85MP0005248_abnormal_Harderian_gland0.78443814
86MP0008260_abnormal_autophagy0.78203542
87MP0001697_abnormal_embryo_size0.78076654
88MP0000579_abnormal_nail_morphology0.78056766
89MP0010771_integument_phenotype0.75374641
90MP0000566_synostosis0.72244541
91MP0002080_prenatal_lethality0.71250978
92MP0000538_abnormal_urinary_bladder0.70015848
93MP0001216_abnormal_epidermal_layer0.69658078
94MP0005330_cardiomyopathy0.69197971
95MP0002086_abnormal_extraembryonic_tissu0.69104930
96MP0000490_abnormal_crypts_of0.67167224
97MP0001986_abnormal_taste_sensitivity0.67109842
98MP0000631_abnormal_neuroendocrine_gland0.62429484
99MP0002084_abnormal_developmental_patter0.61725795
100MP0003984_embryonic_growth_retardation0.60867383

Predicted human phenotypes

RankGene SetZ-score
1Hypoplasia of the uterus (HP:0000013)6.58766508
2Aplasia/hypoplasia of the uterus (HP:0008684)5.48976884
3Facial hemangioma (HP:0000329)5.17243635
4Thoracolumbar scoliosis (HP:0002944)4.40697742
5Resting tremor (HP:0002322)4.21712594
6Reduced antithrombin III activity (HP:0001976)4.21611697
7Lip pit (HP:0100267)4.21064082
8Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)3.91567526
9Absent epiphyses (HP:0010577)3.91567526
10Abnormal tarsal ossification (HP:0008369)3.90993752
11Pili torti (HP:0003777)3.87785492
12Hypoplastic ischia (HP:0003175)3.74574496
13Thoracic kyphosis (HP:0002942)3.56280018
14Abnormal sex determination (HP:0012244)3.44867975
15Sex reversal (HP:0012245)3.44867975
16Capillary hemangiomas (HP:0005306)3.41941948
17Abnormality of the columella (HP:0009929)3.39993739
18Abnormality of the ischium (HP:0003174)3.24411062
19Vitreoretinal degeneration (HP:0000655)3.20278326
20Flattened epiphyses (HP:0003071)3.11226075
21Abnormality of the lumbar spine (HP:0100712)3.07454476
22Epiphyseal dysplasia (HP:0002656)3.06922796
23Hypotrichosis (HP:0001006)3.05883134
24Gonadotropin excess (HP:0000837)3.02357921
25Hypoplastic pelvis (HP:0008839)2.97478316
26Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.88501970
27High anterior hairline (HP:0009890)2.79346404
28Germ cell neoplasia (HP:0100728)2.78388464
29Aplasia cutis congenita (HP:0001057)2.77611001
30Gonadal dysgenesis (HP:0000133)2.75060094
31Flat acetabular roof (HP:0003180)2.74377421
32Urinary urgency (HP:0000012)2.60796704
33Abnormality of cochlea (HP:0000375)2.59445476
34Infertility (HP:0000789)2.57827387
35Vertebral clefting (HP:0008428)2.54676833
36Abnormal foot bone ossification (HP:0010675)2.54454353
37Abnormality of the thoracic spine (HP:0100711)2.53907152
38Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.53484755
39Abnormal spermatogenesis (HP:0008669)2.51925851
40Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.51790741
41Azoospermia (HP:0000027)2.48718458
42Absent thumb (HP:0009777)2.48659380
43Male infertility (HP:0003251)2.47826116
44Proximal placement of thumb (HP:0009623)2.47496591
45Abnormal pancreas size (HP:0012094)2.43425053
46Self-mutilation (HP:0000742)2.42203202
47Abnormality of the proximal phalanges of the hand (HP:0009834)2.40208786
48Deviation of the thumb (HP:0009603)2.38285645
49Glossoptosis (HP:0000162)2.37844417
50Male pseudohermaphroditism (HP:0000037)2.35087070
51Carpal bone hypoplasia (HP:0001498)2.34405974
52Onycholysis (HP:0001806)2.34119224
53Morphological abnormality of the inner ear (HP:0011390)2.33665444
54Absent radius (HP:0003974)2.32668826
55Metaphyseal cupping (HP:0003021)2.29290286
56Abnormality of the phalanges of the 2nd finger (HP:0009541)2.26682525
57Protuberant abdomen (HP:0001538)2.24715610
58Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.22638896
59Abnormal protein N-linked glycosylation (HP:0012347)2.22638896
60Abnormal protein glycosylation (HP:0012346)2.22638896
61Abnormal glycosylation (HP:0012345)2.22638896
62Postural instability (HP:0002172)2.18186051
63Aplasia involving forearm bones (HP:0009822)2.16452221
64Absent forearm bone (HP:0003953)2.16452221
65Hip contracture (HP:0003273)2.15391602
66Short thumb (HP:0009778)2.14792725
67Cervical subluxation (HP:0003308)2.13514456
68Ureteral duplication (HP:0000073)2.13060531
69Abnormal respiratory motile cilium physiology (HP:0012261)2.12080606
70Cerebral hypomyelination (HP:0006808)2.12048579
71Squamous cell carcinoma (HP:0002860)2.11212339
72Posterior subcapsular cataract (HP:0007787)2.08372915
73Abnormality of the intrinsic pathway (HP:0010989)2.03895364
74Mixed hearing impairment (HP:0000410)2.03230993
75Aplasia/Hypoplasia involving the musculature (HP:0001460)2.01915541
76Ileus (HP:0002595)2.01552734
77Flat capital femoral epiphysis (HP:0003370)2.01490032
78Chromsome breakage (HP:0040012)2.01115925
79Cerebellar dysplasia (HP:0007033)1.96914200
80Abnormality of the salivary glands (HP:0010286)1.92649509
81Delayed epiphyseal ossification (HP:0002663)1.92128584
82Unsteady gait (HP:0002317)1.91322367
83Irregular epiphyses (HP:0010582)1.88590994
84Abnormal ciliary motility (HP:0012262)1.88169795
85Abnormality of the preputium (HP:0100587)1.83151235
86Abnormality of the ileum (HP:0001549)1.80317972
87Abnormal hair laboratory examination (HP:0003328)1.78983774
88Neonatal short-limb short stature (HP:0008921)1.78459591
89Abnormality of DNA repair (HP:0003254)1.77050545
90Difficulty climbing stairs (HP:0003551)1.75523529
91Aplasia/Hypoplasia of the ulna (HP:0006495)1.74737132
92Palpitations (HP:0001962)1.74310157
93Slow-growing hair (HP:0002217)1.73153224
94Abnormality of hair growth rate (HP:0011363)1.73153224
95Chronic bronchitis (HP:0004469)1.71506726
96Premature ovarian failure (HP:0008209)1.69475135
97Chromosomal breakage induced by crosslinking agents (HP:0003221)1.68992396
98Sensory axonal neuropathy (HP:0003390)1.68589811
99Brittle hair (HP:0002299)1.68393283
100Type II lissencephaly (HP:0007260)1.66920514

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS17.01403928
2PINK15.90765915
3MST44.55334439
4MARK33.81960671
5MST1R3.44066686
6STK38L2.86331533
7ZAK2.72423915
8TLK12.54513704
9NME22.26530704
10NUAK12.26137924
11PLK42.18861671
12MET2.12008862
13MYLK2.10516907
14BUB12.08174397
15LATS21.96631536
16EPHA21.94896524
17NEK21.91281497
18LMTK21.90787074
19MAP3K91.87134951
20DDR21.69332117
21MAPK151.68115745
22STK31.58830363
23PBK1.34346740
24RPS6KA51.28428007
25CSNK1A1L1.25704575
26PNCK1.23468467
27EIF2AK31.20342194
28CSNK1G31.18228488
29RPS6KA41.12408770
30VRK11.11234541
31SRPK11.08488110
32STK381.07539599
33ARAF1.05018686
34STK240.96722658
35WEE10.89813710
36CDK30.89162182
37CSNK1G10.87579900
38FGR0.83902520
39PLK10.83184877
40MAP3K130.77760753
41CSNK1G20.75035928
42PTK2B0.69652708
43ILK0.66987993
44PRKCI0.64841672
45STK100.64213471
46TESK20.64136674
47PLK20.62807974
48PKN20.61499338
49BRSK10.56276315
50STK160.54628754
51AURKB0.54075718
52MAP2K70.50120153
53MAP3K80.50028918
54AKT20.47838505
55PRKG20.43467731
56TRPM70.43149868
57AURKA0.42997541
58KDR0.42217994
59MTOR0.42110842
60MELK0.40863504
61ROCK10.40030308
62PLK30.40023962
63NEK60.39993474
64PAK10.39736046
65BMX0.39044260
66NME10.38124076
67NEK10.38103041
68CDK120.35617363
69PDGFRB0.34948527
70PRKCQ0.34227680
71PDK20.33845446
72PTK20.33595920
73WNK40.33441690
74CDK140.33216118
75DYRK30.32636714
76CHEK10.32469166
77CDC42BPA0.32300966
78MAP3K10.30832719
79VRK20.30057848
80RPS6KB20.29663371
81TSSK60.29371875
82CDC70.28335617
83EGFR0.28223259
84PKN10.27665440
85ATM0.26857177
86PAK40.25104295
87CSNK1E0.23638425
88OXSR10.22620014
89MOS0.22400476
90WNK10.21821616
91RET0.20709861
92CDK70.20313248
93CSNK2A10.20158379
94CDK90.18798724
95ATR0.17899355
96DAPK30.17432174
97CSNK1A10.16787590
98TRIM280.15952636
99MAP3K100.15554491
100TESK10.15308326

Predicted pathways (KEGG)

RankGene SetZ-score
1Pathogenic Escherichia coli infection_Homo sapiens_hsa051305.98820627
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.55956615
3Gap junction_Homo sapiens_hsa045403.05033822
4Basal transcription factors_Homo sapiens_hsa030222.91746920
5Proteasome_Homo sapiens_hsa030502.89509850
6DNA replication_Homo sapiens_hsa030302.66930527
7Systemic lupus erythematosus_Homo sapiens_hsa053222.55693516
8Oocyte meiosis_Homo sapiens_hsa041142.45107293
9RNA transport_Homo sapiens_hsa030132.41864529
10Cell cycle_Homo sapiens_hsa041102.13231588
11mRNA surveillance pathway_Homo sapiens_hsa030152.12582574
12Apoptosis_Homo sapiens_hsa042102.09861019
13Olfactory transduction_Homo sapiens_hsa047401.99470365
14RNA polymerase_Homo sapiens_hsa030201.96870512
15Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.96532740
16Hedgehog signaling pathway_Homo sapiens_hsa043401.96347525
17Homologous recombination_Homo sapiens_hsa034401.94460565
18Alcoholism_Homo sapiens_hsa050341.84658022
19Fanconi anemia pathway_Homo sapiens_hsa034601.83776676
20Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.77057187
21Nitrogen metabolism_Homo sapiens_hsa009101.57809000
22Pyrimidine metabolism_Homo sapiens_hsa002401.56566378
23Cysteine and methionine metabolism_Homo sapiens_hsa002701.52475464
24Mismatch repair_Homo sapiens_hsa034301.52383407
25Phototransduction_Homo sapiens_hsa047441.50667240
26RNA degradation_Homo sapiens_hsa030181.44368332
27Sulfur relay system_Homo sapiens_hsa041221.44334606
28Regulation of autophagy_Homo sapiens_hsa041401.43112430
29Phagosome_Homo sapiens_hsa041451.19412380
30Spliceosome_Homo sapiens_hsa030401.17999465
31Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.14514614
32Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.10394767
33Pyruvate metabolism_Homo sapiens_hsa006201.10154219
34Purine metabolism_Homo sapiens_hsa002301.07903779
35Asthma_Homo sapiens_hsa053101.03292743
36Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.02951912
37Dorso-ventral axis formation_Homo sapiens_hsa043200.97122657
38Base excision repair_Homo sapiens_hsa034100.94765533
39Propanoate metabolism_Homo sapiens_hsa006400.93319683
40ECM-receptor interaction_Homo sapiens_hsa045120.92781359
41Phenylalanine metabolism_Homo sapiens_hsa003600.90149078
42Pentose phosphate pathway_Homo sapiens_hsa000300.84739301
43Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.84538841
44Arginine biosynthesis_Homo sapiens_hsa002200.83928222
45Viral carcinogenesis_Homo sapiens_hsa052030.82499357
46Protein digestion and absorption_Homo sapiens_hsa049740.81977724
47Nucleotide excision repair_Homo sapiens_hsa034200.80410312
48Glutathione metabolism_Homo sapiens_hsa004800.80103045
49Steroid hormone biosynthesis_Homo sapiens_hsa001400.79702025
50Tight junction_Homo sapiens_hsa045300.77696378
51Taste transduction_Homo sapiens_hsa047420.74886244
52Wnt signaling pathway_Homo sapiens_hsa043100.74826007
53p53 signaling pathway_Homo sapiens_hsa041150.69579361
54Prostate cancer_Homo sapiens_hsa052150.68802415
55Parkinsons disease_Homo sapiens_hsa050120.68391043
56Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.68299657
57Folate biosynthesis_Homo sapiens_hsa007900.65968890
58Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.64896163
59N-Glycan biosynthesis_Homo sapiens_hsa005100.64807587
60cGMP-PKG signaling pathway_Homo sapiens_hsa040220.64511689
61Ribosome_Homo sapiens_hsa030100.62524270
62Gastric acid secretion_Homo sapiens_hsa049710.57786045
63Small cell lung cancer_Homo sapiens_hsa052220.57356218
64Fructose and mannose metabolism_Homo sapiens_hsa000510.57198405
65Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.55923881
66Chemical carcinogenesis_Homo sapiens_hsa052040.55667357
67Lysine degradation_Homo sapiens_hsa003100.55472034
68Huntingtons disease_Homo sapiens_hsa050160.54960852
69Thyroid cancer_Homo sapiens_hsa052160.53193317
70Vitamin B6 metabolism_Homo sapiens_hsa007500.52112775
71Hippo signaling pathway_Homo sapiens_hsa043900.52045204
72Vascular smooth muscle contraction_Homo sapiens_hsa042700.51549830
73Steroid biosynthesis_Homo sapiens_hsa001000.50790730
74Longevity regulating pathway - mammal_Homo sapiens_hsa042110.46465603
75beta-Alanine metabolism_Homo sapiens_hsa004100.46460293
76Tyrosine metabolism_Homo sapiens_hsa003500.45727738
77Focal adhesion_Homo sapiens_hsa045100.43924758
78Glucagon signaling pathway_Homo sapiens_hsa049220.43840775
79Adherens junction_Homo sapiens_hsa045200.43111790
80Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.42926964
81Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.41417249
82Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.35858952
83Herpes simplex infection_Homo sapiens_hsa051680.32022477
84Metabolic pathways_Homo sapiens_hsa011000.30885281
85Transcriptional misregulation in cancer_Homo sapiens_hsa052020.29876244
86T cell receptor signaling pathway_Homo sapiens_hsa046600.29779913
87Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.28370072
88Legionellosis_Homo sapiens_hsa051340.25354977
89TGF-beta signaling pathway_Homo sapiens_hsa043500.22998008
90Ovarian steroidogenesis_Homo sapiens_hsa049130.22808242
91Melanogenesis_Homo sapiens_hsa049160.20943919
92HTLV-I infection_Homo sapiens_hsa051660.20666902
93Drug metabolism - other enzymes_Homo sapiens_hsa009830.19982181
94Oxytocin signaling pathway_Homo sapiens_hsa049210.18265921
95Carbon metabolism_Homo sapiens_hsa012000.17947011
96Glycerophospholipid metabolism_Homo sapiens_hsa005640.17929386
97Sphingolipid metabolism_Homo sapiens_hsa006000.14453023
98Glioma_Homo sapiens_hsa052140.14438032
99Epstein-Barr virus infection_Homo sapiens_hsa051690.14091740
100Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.13805442

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »