CXORF23

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1behavioral response to nicotine (GO:0035095)5.27723413
2pyrimidine nucleobase catabolic process (GO:0006208)4.37883018
3L-fucose catabolic process (GO:0042355)3.89879690
4fucose catabolic process (GO:0019317)3.89879690
5L-fucose metabolic process (GO:0042354)3.89879690
6nucleobase catabolic process (GO:0046113)3.84016882
7epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.82838384
8water-soluble vitamin biosynthetic process (GO:0042364)3.78400386
9neural tube formation (GO:0001841)3.71032029
10response to pheromone (GO:0019236)3.68823213
11presynaptic membrane organization (GO:0097090)3.49002848
12nonmotile primary cilium assembly (GO:0035058)3.32326923
13olfactory bulb development (GO:0021772)3.31725524
14regulation of cilium movement (GO:0003352)3.28924839
15cornea development in camera-type eye (GO:0061303)3.27222311
16serotonin metabolic process (GO:0042428)3.25378753
17indolalkylamine metabolic process (GO:0006586)3.23677340
18presynaptic membrane assembly (GO:0097105)3.15588487
19kidney morphogenesis (GO:0060993)3.12165546
20limb bud formation (GO:0060174)3.11150652
21gamma-aminobutyric acid transport (GO:0015812)3.09427295
22primary amino compound metabolic process (GO:1901160)3.07352876
23establishment of protein localization to Golgi (GO:0072600)3.04277092
24detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.98248387
25detection of light stimulus involved in sensory perception (GO:0050962)2.97364966
26detection of light stimulus involved in visual perception (GO:0050908)2.97364966
27epithelial cilium movement (GO:0003351)2.94757040
28negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.89403533
29negative regulation of translation, ncRNA-mediated (GO:0040033)2.89403533
30regulation of translation, ncRNA-mediated (GO:0045974)2.89403533
31neuronal action potential (GO:0019228)2.89045507
32cell proliferation in forebrain (GO:0021846)2.87799724
33G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.83410242
34single strand break repair (GO:0000012)2.83004718
35positive regulation of sodium ion transmembrane transporter activity (GO:2000651)2.81891596
36indole-containing compound metabolic process (GO:0042430)2.78436515
37tryptophan catabolic process (GO:0006569)2.78238917
38indole-containing compound catabolic process (GO:0042436)2.78238917
39indolalkylamine catabolic process (GO:0046218)2.78238917
40platelet dense granule organization (GO:0060155)2.74643017
41cilium organization (GO:0044782)2.72319993
42retinal cone cell development (GO:0046549)2.72297137
43cilium morphogenesis (GO:0060271)2.71267944
44startle response (GO:0001964)2.69185249
45head development (GO:0060322)2.69007442
46protein targeting to Golgi (GO:0000042)2.68731100
47regulation of action potential (GO:0098900)2.68454750
48intraciliary transport (GO:0042073)2.68434598
49cilium assembly (GO:0042384)2.66794674
50retinal ganglion cell axon guidance (GO:0031290)2.65875229
51negative regulation of cytosolic calcium ion concentration (GO:0051481)2.65397109
52protein localization to cilium (GO:0061512)2.64984102
53mitochondrial respiratory chain complex I assembly (GO:0032981)2.64511383
54NADH dehydrogenase complex assembly (GO:0010257)2.64511383
55mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.64511383
56regulation of acrosome reaction (GO:0060046)2.63336804
57parturition (GO:0007567)2.62342749
58axonal fasciculation (GO:0007413)2.62329696
59inositol phosphate catabolic process (GO:0071545)2.61902453
60regulation of telomere maintenance (GO:0032204)2.61566677
61protein K11-linked deubiquitination (GO:0035871)2.61171843
62somite development (GO:0061053)2.60118621
63dopamine transport (GO:0015872)2.59272205
64behavioral response to ethanol (GO:0048149)2.58466704
65dendritic spine morphogenesis (GO:0060997)2.57252089
66piRNA metabolic process (GO:0034587)2.55774537
67protein localization to Golgi apparatus (GO:0034067)2.55196292
68cyclic nucleotide catabolic process (GO:0009214)2.54426357
69photoreceptor cell development (GO:0042461)2.54307065
70postsynaptic membrane organization (GO:0001941)2.54108449
71cAMP catabolic process (GO:0006198)2.52813239
72protein polyglutamylation (GO:0018095)2.52450063
73spinal cord development (GO:0021510)2.51931608
74kynurenine metabolic process (GO:0070189)2.51680500
75auditory behavior (GO:0031223)2.51557508
76glutamate receptor signaling pathway (GO:0007215)2.51255613
77cellular ketone body metabolic process (GO:0046950)2.51110384
78transmission of nerve impulse (GO:0019226)2.50677580
79photoreceptor cell maintenance (GO:0045494)2.50575380
80respiratory chain complex IV assembly (GO:0008535)2.50051235
81synaptic transmission, cholinergic (GO:0007271)2.49581529
82mechanosensory behavior (GO:0007638)2.48873252
83regulation of microtubule-based movement (GO:0060632)2.48000316
84polyol catabolic process (GO:0046174)2.47617885
85retrograde transport, vesicle recycling within Golgi (GO:0000301)2.47223266
86cilium movement (GO:0003341)2.46520644
87membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.46295424
88adaptation of signaling pathway (GO:0023058)2.44193532
89embryonic epithelial tube formation (GO:0001838)2.43965956
90protein complex biogenesis (GO:0070271)2.43758296
91DNA methylation involved in gamete generation (GO:0043046)2.43628015
92protein K6-linked ubiquitination (GO:0085020)2.42515610
93brain morphogenesis (GO:0048854)2.42000613
94axoneme assembly (GO:0035082)2.41788569
95tryptophan metabolic process (GO:0006568)2.41326605
96negative regulation of neurotransmitter transport (GO:0051589)2.41294157
97neuronal action potential propagation (GO:0019227)2.40348124
98reflex (GO:0060004)2.39997781
99ionotropic glutamate receptor signaling pathway (GO:0035235)2.38265225
100locomotory exploration behavior (GO:0035641)2.38129489

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.51373144
2GBX2_23144817_ChIP-Seq_PC3_Human3.25180021
3ZNF274_21170338_ChIP-Seq_K562_Hela2.90462474
4VDR_22108803_ChIP-Seq_LS180_Human2.87779444
5ZFP57_27257070_Chip-Seq_ESCs_Mouse2.57197976
6GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.44478060
7CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.42735889
8POU3F2_20337985_ChIP-ChIP_501MEL_Human2.42222003
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.37280604
10IGF1R_20145208_ChIP-Seq_DFB_Human2.36425468
11CTBP2_25329375_ChIP-Seq_LNCAP_Human2.31347783
12TAF15_26573619_Chip-Seq_HEK293_Human2.13943528
13SALL1_21062744_ChIP-ChIP_HESCs_Human2.08997358
14FUS_26573619_Chip-Seq_HEK293_Human2.07252327
15CTBP1_25329375_ChIP-Seq_LNCAP_Human2.04776122
16P300_19829295_ChIP-Seq_ESCs_Human2.03929058
17FLI1_27457419_Chip-Seq_LIVER_Mouse1.97039566
18AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.94864678
19SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.91308431
20EWS_26573619_Chip-Seq_HEK293_Human1.90317179
21HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.86241908
22PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.86092383
23ER_23166858_ChIP-Seq_MCF-7_Human1.79348791
24SMAD4_21799915_ChIP-Seq_A2780_Human1.78360812
25PIAS1_25552417_ChIP-Seq_VCAP_Human1.75186203
26STAT3_23295773_ChIP-Seq_U87_Human1.63715396
27BCAT_22108803_ChIP-Seq_LS180_Human1.61836015
28UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.61705233
29MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.61147312
30TCF4_23295773_ChIP-Seq_U87_Human1.59158006
31CBX2_27304074_Chip-Seq_ESCs_Mouse1.58910844
32REST_21632747_ChIP-Seq_MESCs_Mouse1.56171241
33ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.55613366
34BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.55150104
35PCGF2_27294783_Chip-Seq_ESCs_Mouse1.55040882
36TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.54468056
37POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.54468056
38AR_25329375_ChIP-Seq_VCAP_Human1.53671751
39SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.53578504
40SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.53338537
41NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.52083298
42TOP2B_26459242_ChIP-Seq_MCF-7_Human1.51048160
43IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.47492431
44CBP_20019798_ChIP-Seq_JUKART_Human1.47492431
45OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.46536860
46RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.45123135
47SMAD3_21741376_ChIP-Seq_EPCs_Human1.45016305
48BMI1_23680149_ChIP-Seq_NPCS_Mouse1.44383635
49TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.40587959
50NANOG_18555785_Chip-Seq_ESCs_Mouse1.39753009
51RNF2_27304074_Chip-Seq_NSC_Mouse1.39670969
52SUZ12_27294783_Chip-Seq_NPCs_Mouse1.38085144
53PRDM14_20953172_ChIP-Seq_ESCs_Human1.35398846
54MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.35103535
55NR3C1_21868756_ChIP-Seq_MCF10A_Human1.34122749
56EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.33064667
57* RUNX2_22187159_ChIP-Seq_PCA_Human1.32743261
58PCGF2_27294783_Chip-Seq_NPCs_Mouse1.31356904
59* TCF4_22108803_ChIP-Seq_LS180_Human1.29848092
60EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.29016373
61EZH2_27294783_Chip-Seq_NPCs_Mouse1.29000166
62NFE2_27457419_Chip-Seq_LIVER_Mouse1.28616606
63TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.27162722
64FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.26703410
65P53_22387025_ChIP-Seq_ESCs_Mouse1.24172384
66FLI1_21867929_ChIP-Seq_TH2_Mouse1.20283982
67TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18633723
68KLF5_20875108_ChIP-Seq_MESCs_Mouse1.18132754
69SOX2_19829295_ChIP-Seq_ESCs_Human1.17376813
70NANOG_19829295_ChIP-Seq_ESCs_Human1.17376813
71TP53_22573176_ChIP-Seq_HFKS_Human1.17272063
72TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.17187873
73MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.16598669
74IRF1_19129219_ChIP-ChIP_H3396_Human1.16145386
75SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.15941573
76E2F1_18555785_Chip-Seq_ESCs_Mouse1.15524014
77SMAD4_21741376_ChIP-Seq_EPCs_Human1.14957672
78AR_21572438_ChIP-Seq_LNCaP_Human1.13938568
79TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.13813693
80EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.13559181
81GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.12489904
82CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.11966503
83EZH2_27304074_Chip-Seq_ESCs_Mouse1.11256772
84SOX2_21211035_ChIP-Seq_LN229_Gbm1.09106395
85SUZ12_18555785_Chip-Seq_ESCs_Mouse1.08917019
86CMYC_18555785_Chip-Seq_ESCs_Mouse1.07043272
87ARNT_22903824_ChIP-Seq_MCF-7_Human1.07010673
88STAT3_18555785_Chip-Seq_ESCs_Mouse1.06379618
89TP53_16413492_ChIP-PET_HCT116_Human1.05644114
90LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05512436
91JARID2_20064375_ChIP-Seq_MESCs_Mouse1.05471992
92KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.05107869
93CRX_20693478_ChIP-Seq_RETINA_Mouse1.04822093
94TAL1_26923725_Chip-Seq_HPCs_Mouse1.04652205
95CDX2_22108803_ChIP-Seq_LS180_Human1.01985599
96P300_18555785_Chip-Seq_ESCs_Mouse1.01854346
97DROSHA_22980978_ChIP-Seq_HELA_Human1.01381656
98STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.01066005
99TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.00930766
100CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00449988

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003787_abnormal_imprinting3.88122067
2MP0000569_abnormal_digit_pigmentation3.43894233
3MP0006292_abnormal_olfactory_placode2.98504856
4MP0008877_abnormal_DNA_methylation2.97685336
5MP0005551_abnormal_eye_electrophysiolog2.33626228
6MP0002638_abnormal_pupillary_reflex2.21124825
7MP0003121_genomic_imprinting2.19780027
8MP0003890_abnormal_embryonic-extraembry2.12534616
9MP0002102_abnormal_ear_morphology2.05994347
10MP0003195_calcinosis2.03959642
11MP0001968_abnormal_touch/_nociception2.00506258
12MP0006276_abnormal_autonomic_nervous1.99113263
13MP0002837_dystrophic_cardiac_calcinosis1.97799244
14MP0009046_muscle_twitch1.97260285
15MP0000778_abnormal_nervous_system1.92136262
16MP0002272_abnormal_nervous_system1.87988795
17MP0003880_abnormal_central_pattern1.86167381
18MP0004142_abnormal_muscle_tone1.84699943
19MP0009745_abnormal_behavioral_response1.82204941
20MP0001984_abnormal_olfaction1.82147681
21MP0002736_abnormal_nociception_after1.81567080
22MP0006072_abnormal_retinal_apoptosis1.78877002
23MP0001986_abnormal_taste_sensitivity1.76142339
24MP0000631_abnormal_neuroendocrine_gland1.68525721
25MP0004133_heterotaxia1.64382349
26MP0004885_abnormal_endolymph1.63752078
27MP0005253_abnormal_eye_physiology1.63551840
28MP0001501_abnormal_sleep_pattern1.61545258
29MP0003122_maternal_imprinting1.60919527
30MP0001486_abnormal_startle_reflex1.60902692
31MP0002876_abnormal_thyroid_physiology1.58396083
32MP0002572_abnormal_emotion/affect_behav1.56195550
33MP0003635_abnormal_synaptic_transmissio1.48502136
34MP0000427_abnormal_hair_cycle1.47892294
35MP0002735_abnormal_chemical_nociception1.46580932
36MP0002938_white_spotting1.45650291
37MP0002557_abnormal_social/conspecific_i1.44711116
38MP0004924_abnormal_behavior1.42759323
39MP0005386_behavior/neurological_phenoty1.42759323
40MP0004145_abnormal_muscle_electrophysio1.40642676
41MP0005645_abnormal_hypothalamus_physiol1.38501688
42MP0001529_abnormal_vocalization1.37900126
43MP0002064_seizures1.37550526
44MP0005646_abnormal_pituitary_gland1.37273617
45MP0003646_muscle_fatigue1.36528541
46MP0002653_abnormal_ependyma_morphology1.35788942
47MP0008789_abnormal_olfactory_epithelium1.35161074
48MP0002751_abnormal_autonomic_nervous1.35058369
49MP0005423_abnormal_somatic_nervous1.34496001
50MP0002063_abnormal_learning/memory/cond1.34449528
51MP0003136_yellow_coat_color1.34383814
52MP0002928_abnormal_bile_duct1.34297442
53MP0001485_abnormal_pinna_reflex1.33444683
54MP0005174_abnormal_tail_pigmentation1.32648030
55MP0002067_abnormal_sensory_capabilities1.29893853
56MP0002909_abnormal_adrenal_gland1.27637856
57MP0002734_abnormal_mechanical_nocicepti1.26644419
58MP0004043_abnormal_pH_regulation1.26238772
59MP0005394_taste/olfaction_phenotype1.24734236
60MP0005499_abnormal_olfactory_system1.24734236
61MP0008872_abnormal_physiological_respon1.23043987
62MP0001970_abnormal_pain_threshold1.22830330
63MP0005075_abnormal_melanosome_morpholog1.20825722
64MP0002234_abnormal_pharynx_morphology1.18556753
65MP0003283_abnormal_digestive_organ1.16636523
66MP0004859_abnormal_synaptic_plasticity1.15378422
67MP0002733_abnormal_thermal_nociception1.14510324
68MP0005195_abnormal_posterior_eye1.14097167
69MP0002184_abnormal_innervation1.14036451
70MP0002752_abnormal_somatic_nervous1.13834374
71MP0004147_increased_porphyrin_level1.13284651
72MP0005084_abnormal_gallbladder_morpholo1.11005444
73MP0004270_analgesia1.08588800
74MP0002882_abnormal_neuron_morphology1.07936394
75MP0000372_irregular_coat_pigmentation1.05297807
76MP0002229_neurodegeneration1.04898959
77MP0002163_abnormal_gland_morphology1.04724609
78MP0000955_abnormal_spinal_cord1.04594174
79MP0003718_maternal_effect1.04060905
80MP0010386_abnormal_urinary_bladder1.00725288
81MP0008775_abnormal_heart_ventricle0.98750929
82MP0004215_abnormal_myocardial_fiber0.94741864
83MP0001502_abnormal_circadian_rhythm0.91223892
84MP0000230_abnormal_systemic_arterial0.91013782
85MP0002160_abnormal_reproductive_system0.90617126
86MP0001905_abnormal_dopamine_level0.88769206
87MP0005379_endocrine/exocrine_gland_phen0.88248053
88MP0005367_renal/urinary_system_phenotyp0.84286406
89MP0000516_abnormal_urinary_system0.84286406
90MP0001440_abnormal_grooming_behavior0.83609924
91MP0003011_delayed_dark_adaptation0.80882535
92MP0001324_abnormal_eye_pigmentation0.78556246
93MP0000049_abnormal_middle_ear0.77926354
94MP0005389_reproductive_system_phenotype0.77347878
95MP0000026_abnormal_inner_ear0.76599988
96MP0008995_early_reproductive_senescence0.76568402
97MP0001188_hyperpigmentation0.76055235
98MP0002693_abnormal_pancreas_physiology0.76018607
99MP0002152_abnormal_brain_morphology0.75007908
100MP0004085_abnormal_heartbeat0.73901834

Predicted human phenotypes

RankGene SetZ-score
1Pancreatic cysts (HP:0001737)4.08885653
2Hyperventilation (HP:0002883)3.93643313
3Pancreatic fibrosis (HP:0100732)3.85494767
4Abnormality of midbrain morphology (HP:0002418)3.79900058
5Molar tooth sign on MRI (HP:0002419)3.79900058
6Medial flaring of the eyebrow (HP:0010747)3.75237847
7Nephronophthisis (HP:0000090)3.62775688
8True hermaphroditism (HP:0010459)3.54845806
9Gait imbalance (HP:0002141)3.30366682
10Chronic hepatic failure (HP:0100626)3.25742169
11Abnormality of the renal medulla (HP:0100957)3.25654554
12Progressive cerebellar ataxia (HP:0002073)3.15293363
13Congenital primary aphakia (HP:0007707)3.13440985
14Congenital stationary night blindness (HP:0007642)3.10443574
15Type II lissencephaly (HP:0007260)3.05445456
16Abnormality of the renal cortex (HP:0011035)3.05368480
17Nephrogenic diabetes insipidus (HP:0009806)2.92334215
18Genital tract atresia (HP:0001827)2.84308264
19Broad-based gait (HP:0002136)2.82041331
20Vaginal atresia (HP:0000148)2.74491670
21Protruding tongue (HP:0010808)2.71477326
22Gaze-evoked nystagmus (HP:0000640)2.69607450
23Abnormal hair whorl (HP:0010721)2.63342599
24Cystic liver disease (HP:0006706)2.54672097
25Genetic anticipation (HP:0003743)2.54248057
26Abnormal rod and cone electroretinograms (HP:0008323)2.49366790
27Poor coordination (HP:0002370)2.48724054
28Oligodactyly (hands) (HP:0001180)2.46741070
29Absent speech (HP:0001344)2.46369550
30Volvulus (HP:0002580)2.45914400
31Fair hair (HP:0002286)2.42564217
32Abolished electroretinogram (ERG) (HP:0000550)2.41835340
33Drooling (HP:0002307)2.41422007
34Lissencephaly (HP:0001339)2.40147905
35Renal cortical cysts (HP:0000803)2.40001267
36Progressive inability to walk (HP:0002505)2.37722899
37Optic nerve hypoplasia (HP:0000609)2.37497918
38Attenuation of retinal blood vessels (HP:0007843)2.36181626
39Tubular atrophy (HP:0000092)2.36007810
40Febrile seizures (HP:0002373)2.35190167
41Inability to walk (HP:0002540)2.33265989
42Aplasia/Hypoplasia of the tongue (HP:0010295)2.32597253
43Polydipsia (HP:0001959)2.31638659
44Abnormal drinking behavior (HP:0030082)2.31638659
45Pachygyria (HP:0001302)2.29226092
46Abnormality of alanine metabolism (HP:0010916)2.24200379
47Hyperalaninemia (HP:0003348)2.24200379
48Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.24200379
49Pendular nystagmus (HP:0012043)2.22681587
50Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.21479080
51Excessive salivation (HP:0003781)2.20344167
52Limb dystonia (HP:0002451)2.19287724
53Widely spaced teeth (HP:0000687)2.17821600
54Absent rod-and cone-mediated responses on ERG (HP:0007688)2.15622403
55Chorioretinal atrophy (HP:0000533)2.15512044
56Intestinal atresia (HP:0011100)2.15096726
57Abnormality of the labia minora (HP:0012880)2.12789875
58Hypothermia (HP:0002045)2.12684204
59Anencephaly (HP:0002323)2.08762658
60Abnormal pancreas size (HP:0012094)2.07386270
61Congenital hepatic fibrosis (HP:0002612)2.05951043
62Sclerocornea (HP:0000647)2.05684130
63Postaxial hand polydactyly (HP:0001162)2.02421733
64Absent/shortened dynein arms (HP:0200106)2.00208999
65Dynein arm defect of respiratory motile cilia (HP:0012255)2.00208999
66Hepatoblastoma (HP:0002884)1.97918712
67Clumsiness (HP:0002312)1.97851845
68Aplasia/Hypoplasia of the tibia (HP:0005772)1.94479505
69Decreased circulating renin level (HP:0003351)1.93489169
70Focal motor seizures (HP:0011153)1.91843574
71Retinal dysplasia (HP:0007973)1.90713874
72Neoplasm of the adrenal cortex (HP:0100641)1.89577852
73Keratoconus (HP:0000563)1.88349357
74Increased corneal curvature (HP:0100692)1.88349357
75Tubulointerstitial nephritis (HP:0001970)1.87321083
76Anterior segment dysgenesis (HP:0007700)1.86946683
77Generalized hypopigmentation of hair (HP:0011358)1.86393286
78Furrowed tongue (HP:0000221)1.86387615
79Focal seizures (HP:0007359)1.84103491
80Decreased central vision (HP:0007663)1.83626722
81Short foot (HP:0001773)1.82027770
82Specific learning disability (HP:0001328)1.81113691
83Dialeptic seizures (HP:0011146)1.79375831
84Bony spicule pigmentary retinopathy (HP:0007737)1.79071332
85Male pseudohermaphroditism (HP:0000037)1.76820517
86Congenital sensorineural hearing impairment (HP:0008527)1.76719795
87Agitation (HP:0000713)1.75353556
88Narrow forehead (HP:0000341)1.74997411
89Methylmalonic acidemia (HP:0002912)1.74790900
90Postaxial foot polydactyly (HP:0001830)1.73324978
91Cerebellar dysplasia (HP:0007033)1.73194628
92Polyuria (HP:0000103)1.72960025
93Hypoplastic labia majora (HP:0000059)1.71863666
94Growth hormone deficiency (HP:0000824)1.70930367
95Labial hypoplasia (HP:0000066)1.70505689
96Dandy-Walker malformation (HP:0001305)1.69204268
97Aqueductal stenosis (HP:0002410)1.69066397
98Abnormal biliary tract physiology (HP:0012439)1.69045518
99Bile duct proliferation (HP:0001408)1.69045518
100Left ventricular hypertrophy (HP:0001712)1.67962501

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.26136273
2BMPR1B4.58026883
3CASK3.87719521
4WNK33.07952216
5ACVR1B3.01943068
6MAPK132.38025259
7PINK12.16290853
8TNIK2.05195293
9MARK12.04946217
10ADRBK22.04052281
11NUAK11.95983909
12MAP4K21.95883894
13MAP3K41.72130524
14MKNK21.57663638
15TAOK31.55004875
16OXSR11.53095863
17GRK11.51864827
18NTRK31.46237967
19IRAK11.45454920
20FGFR21.44440052
21PIK3CA1.35314891
22PAK31.27643971
23ZAK1.25899157
24WNK41.22028435
25TLK11.16215594
26TRPM71.15238999
27DYRK21.13617666
28NTRK21.10927097
29CSNK1G21.06932394
30MARK31.06250814
31SGK21.05429378
32INSRR1.04907538
33STK391.03673626
34MAP2K71.03478697
35PRKCG1.03414890
36MAP3K91.03264894
37AKT30.98211130
38CSNK1G10.91110773
39PRKCE0.90642901
40PHKG20.90581571
41PHKG10.90581571
42ERBB30.89758803
43BCR0.88140942
44CSNK1G30.85767652
45CDK190.85067982
46SGK2230.81779479
47SGK4940.81779479
48SIK20.78047222
49MINK10.76867472
50PLK20.74872893
51ADRBK10.74289451
52STK38L0.72584257
53DAPK20.72313527
54TGFBR10.70949423
55EPHA40.70274709
56STK110.68896311
57MAPK150.68435791
58PRKCZ0.67045082
59OBSCN0.66734361
60MAP2K40.66712775
61TRIM280.66608772
62MKNK10.66123796
63CAMKK20.65159488
64BRSK20.64342293
65NLK0.59684111
66CSNK1A1L0.58805187
67TEC0.58426633
68PNCK0.57995756
69TNK20.56546010
70CSNK1D0.56510724
71KIT0.50725800
72CAMK2A0.50353087
73TXK0.49130075
74PRKACA0.48940593
75STK30.48489517
76YES10.47270203
77CDK30.47100767
78PIK3CG0.46436749
79PKN10.43713823
80DYRK1A0.43494825
81MAP3K120.42791735
82PRKAA10.41310817
83PRKG10.41120206
84NEK20.40522891
85PTK2B0.39658481
86PASK0.39194214
87CSNK1A10.38692466
88PRKACB0.38229576
89PRKCQ0.38089900
90MST40.37786672
91PRKAA20.36800708
92HIPK20.36189292
93CDK50.35802788
94TIE10.35437840
95SGK30.34797700
96SGK10.34225851
97MAP2K60.33415981
98CAMK10.33292209
99ERBB20.32692410
100CHUK0.31993172

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.07914439
2Phototransduction_Homo sapiens_hsa047442.94790387
3Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.61551493
4Maturity onset diabetes of the young_Homo sapiens_hsa049502.51936582
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.46644811
6Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.17881416
7Nitrogen metabolism_Homo sapiens_hsa009102.16927828
8Butanoate metabolism_Homo sapiens_hsa006502.11343634
9Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.01691975
10Linoleic acid metabolism_Homo sapiens_hsa005912.01011501
11Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.93058503
12Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.85817740
13alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.81613387
14Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.79504704
15Caffeine metabolism_Homo sapiens_hsa002321.75142708
16Selenocompound metabolism_Homo sapiens_hsa004501.65827806
17Ether lipid metabolism_Homo sapiens_hsa005651.62082128
18Morphine addiction_Homo sapiens_hsa050321.62050790
19Basal transcription factors_Homo sapiens_hsa030221.53304409
20Glutamatergic synapse_Homo sapiens_hsa047241.50985474
21Olfactory transduction_Homo sapiens_hsa047401.50420618
22Insulin secretion_Homo sapiens_hsa049111.50410675
23Taste transduction_Homo sapiens_hsa047421.50000363
24Protein export_Homo sapiens_hsa030601.49622942
25ABC transporters_Homo sapiens_hsa020101.48703082
26Circadian rhythm_Homo sapiens_hsa047101.47580352
27Cocaine addiction_Homo sapiens_hsa050301.40181148
28Circadian entrainment_Homo sapiens_hsa047131.40006688
29Oxidative phosphorylation_Homo sapiens_hsa001901.39400385
30Tryptophan metabolism_Homo sapiens_hsa003801.38344127
31Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.38337604
32GABAergic synapse_Homo sapiens_hsa047271.36685972
33Serotonergic synapse_Homo sapiens_hsa047261.34451849
34Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.32075061
35Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.31056779
36Dopaminergic synapse_Homo sapiens_hsa047281.21764184
37Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.14625831
38Amphetamine addiction_Homo sapiens_hsa050311.14080145
39Collecting duct acid secretion_Homo sapiens_hsa049661.12074035
40Fanconi anemia pathway_Homo sapiens_hsa034601.07945741
41Propanoate metabolism_Homo sapiens_hsa006401.07623929
42Dorso-ventral axis formation_Homo sapiens_hsa043201.06674618
43Long-term depression_Homo sapiens_hsa047301.05066106
44Regulation of autophagy_Homo sapiens_hsa041401.03367107
45Steroid hormone biosynthesis_Homo sapiens_hsa001401.01185428
46Cardiac muscle contraction_Homo sapiens_hsa042601.00721875
47Hedgehog signaling pathway_Homo sapiens_hsa043400.99147562
48Parkinsons disease_Homo sapiens_hsa050120.98486958
49Peroxisome_Homo sapiens_hsa041460.97410828
50Glycerolipid metabolism_Homo sapiens_hsa005610.90510597
51Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.90163914
52RNA degradation_Homo sapiens_hsa030180.88063974
53Homologous recombination_Homo sapiens_hsa034400.87641092
54Primary bile acid biosynthesis_Homo sapiens_hsa001200.84660508
55Ovarian steroidogenesis_Homo sapiens_hsa049130.84443624
56Axon guidance_Homo sapiens_hsa043600.82540043
57RNA polymerase_Homo sapiens_hsa030200.81786641
58Calcium signaling pathway_Homo sapiens_hsa040200.81570493
59Cholinergic synapse_Homo sapiens_hsa047250.81115979
60Salivary secretion_Homo sapiens_hsa049700.78431141
61cAMP signaling pathway_Homo sapiens_hsa040240.78395955
62Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.78190439
63Non-homologous end-joining_Homo sapiens_hsa034500.76881262
64Chemical carcinogenesis_Homo sapiens_hsa052040.74931143
65Oxytocin signaling pathway_Homo sapiens_hsa049210.74685004
66Synaptic vesicle cycle_Homo sapiens_hsa047210.74029354
67Retinol metabolism_Homo sapiens_hsa008300.73937197
68Renin secretion_Homo sapiens_hsa049240.72626232
69beta-Alanine metabolism_Homo sapiens_hsa004100.68297368
70Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.68099911
71Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.65438760
72Fatty acid biosynthesis_Homo sapiens_hsa000610.63318258
73Type II diabetes mellitus_Homo sapiens_hsa049300.61435786
74Mineral absorption_Homo sapiens_hsa049780.60777731
75Huntingtons disease_Homo sapiens_hsa050160.60316341
76Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.59869052
77Vascular smooth muscle contraction_Homo sapiens_hsa042700.58994686
78Alzheimers disease_Homo sapiens_hsa050100.58454448
79Steroid biosynthesis_Homo sapiens_hsa001000.58201914
80Glycerophospholipid metabolism_Homo sapiens_hsa005640.57432141
81Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.53249607
82Fat digestion and absorption_Homo sapiens_hsa049750.49762324
83Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.49587896
84Sphingolipid metabolism_Homo sapiens_hsa006000.47900019
85Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.47864656
86SNARE interactions in vesicular transport_Homo sapiens_hsa041300.47665387
87Carbohydrate digestion and absorption_Homo sapiens_hsa049730.47222057
88Arachidonic acid metabolism_Homo sapiens_hsa005900.45842971
89Basal cell carcinoma_Homo sapiens_hsa052170.43882034
90Type I diabetes mellitus_Homo sapiens_hsa049400.43829572
91Gastric acid secretion_Homo sapiens_hsa049710.43807667
92Histidine metabolism_Homo sapiens_hsa003400.39927348
93African trypanosomiasis_Homo sapiens_hsa051430.37541380
94Aldosterone synthesis and secretion_Homo sapiens_hsa049250.37265370
95Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.35988554
96TGF-beta signaling pathway_Homo sapiens_hsa043500.35289698
97Ras signaling pathway_Homo sapiens_hsa040140.34806901
98Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.34282276
99FoxO signaling pathway_Homo sapiens_hsa040680.34040181
100Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.33977798

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »